MCID: CNG015
MIFTS: 58

Congenital Diaphragmatic Hernia malady

Categories: Genetic diseases, Rare diseases, Gastrointestinal diseases, Respiratory diseases, Fetal diseases, Muscle diseases

Aliases & Classifications for Congenital Diaphragmatic Hernia

About this section
Sources:
11Disease Ontology, 22GeneReviews, 46NIH Rare Diseases, 23GeneTests, 24Genetics Home Reference, 13DISEASES, 52Orphanet, 25GTR, 48Novoseek, 37MeSH, 28ICD10, 43NCIt, 66UMLS, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 60SNOMED-CT, 62The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Congenital Diaphragmatic Hernia:

Name: Congenital Diaphragmatic Hernia 11 22 46 23 24 13 52 25
Cdh 46 23 52
Congenital Diaphragmatic Defect 46 24
Unilateral Agenesis of Diaphragm 46
Hernia Diaphragmatic Congenital 48
 
Agenesis of Hemidiaphragm 46
Hernia, Diaphragmatic 37
Diaphragmatic Hernia 11
Hernia Diaphragmatic 48

Characteristics:

Orphanet epidemiological data:

52
congenital diaphragmatic hernia:
Inheritance: Multigenic/multifactorial,Not applicable; Prevalence: 1-5/10000 (Worldwide),1-5/10000 (Europe),1-5/10000 (Austria),1-5/10000 (Belgium),1-5/10000 (Croatia),1-5/10000 (Denmark),1-5/10000 (France),1-9/100000 (Germany),1-5/10000 (Hungary),1-5/10000 (Ireland),1-5/10000 (Italy),1-5/10000 (Malta),1-5/10000 (Netherlands),1-5/10000 (Norway),1-9/100000 (Poland),1-5/10000 (Portugal),1-9/100000 (Spain),1-5/10000 (Switzerland),1-5/10000 (United Kingdom),1-5/10000 (Ukraine); Age of onset: Neonatal; Age of death: early childhood

HPO:

62


Classifications:



External Ids:

Disease Ontology11 DOID:3827
MeSH37 D006548
NCIt43 C34687
Orphanet52 ORPHA2140
ICD10 via Orphanet29 Q79.0
MESH via Orphanet38 C538080
UMLS via Orphanet67 C0235833

Summaries for Congenital Diaphragmatic Hernia

About this section
NIH Rare Diseases:46 Congenital diaphragmatic hernia (cdh) is the lack of development before birth of all or part of the diaphragm, which normally separates the organs in the abdomen from those in the chest cavity. it can range in severity from a thinned area in the diaphragm to its complete absence. cdh may allow the stomach and intestines to move into the chest cavity, crowding the heart and lungs. this can then lead to underdevelopment of the lungs (pulmonary hypoplasia), potentially causing life-threatening complications. cdh has many different causes and occurs with other malformations in some cases. treatment options depend on the severity of the defect. last updated: 11/27/2012

MalaCards based summary: Congenital Diaphragmatic Hernia, also known as cdh, is related to esophageal atresia and dih1-related congenital diaphragmatic hernia, and has symptoms including congenital diaphragmatic hernia, congenital diaphragmatic hernia and Array. An important gene associated with Congenital Diaphragmatic Hernia is ZFPM2 (Zinc Finger Protein, FOG Family Member 2), and among its related pathways is Surfactant metabolism. Affiliated tissues include lung, heart and liver, and related mouse phenotypes are muscle and digestive/alimentary.

Disease Ontology:11 A diaphragm disease characterized by the lack of development of all or part of the diaphragm, which results in an abnormal opening that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs.

Genetics Home Reference:24 Congenital diaphragmatic hernia is a defect in the diaphragm. The diaphragm, which is composed of muscle and other fibrous tissue, separates the organs in the abdomen from those in the chest. Abnormal development of the diaphragm before birth leads to defects ranging from a thinned area in the diaphragm to its complete absence. An absent or partially formed diaphragm results in an abnormal opening (hernia) that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs. This crowding can lead to underdevelopment of the lungs (pulmonary hypoplasia), potentially resulting in life-threatening breathing difficulties that are apparent from birth.

Wikipedia:69 Congenital diaphragmatic hernia (CDH) is a birth defect of the diaphragm. The most common type of CDH is... more...

GeneReviews summary for NBK1359

Related Diseases for Congenital Diaphragmatic Hernia

About this section

Diseases in the Congenital Diaphragmatic Hernia family:

Diaphragmatic Hernia 3 Dih1-Related Congenital Diaphragmatic Hernia

Diseases related to Congenital Diaphragmatic Hernia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 138)
idRelated DiseaseScoreTop Affiliating Genes
1esophageal atresia31.3STRA6, ZFPM2
2dih1-related congenital diaphragmatic hernia12.1
3hiatus hernia11.4
4craniofacial-deafness-hand syndrome11.3
5fryns syndrome10.8
6straddling and/or overriding mitral valve10.8GATA4, GATA6
7drug-induced vasculitis10.7GATA4, ZFPM2
8childhood teratoma of the ovary10.7SFTPC, WT1
9large cell keratinizing variant squamous cell breast carcinoma10.7ELN, NKX2-1, WT1
10neovascular glaucoma10.6GATA4, GATA6, ZFPM2
11partial duplication of the short arm of chromosome x10.6GATA4, GATA6, NR2F2
12melanotic neuroectodermal tumor10.6GATA4, GATA6, ZFPM2
13esophagus adenocarcinoma10.6SFTPC, WT1
14photokeratitis10.6GATA4, GATA6, NKX2-1
15surfactant metabolism dysfunction, pulmonary, 210.5GATA4, GATA6, ZFPM2
16pulmonary hypertension10.5
17uniparental disomy of chromosome 1110.5EDN1, GATA6, NR2F2
18apoa1-related familial visceral amyloidosis10.5FREM1, STRA6
19fetal alcohol syndrome10.5EDN1, GATA4, GATA6
20malignant peritoneal solitary fibrous tumor10.5NKX2-1, WT1
21esophagitis10.5
22dhdds-cdg10.5GATA4, GATA6, NR2F2, ZFPM2
23anonychia with flexural pigmentation10.4SFTPB, SFTPC
24urethra adenocarcinoma10.4NKX2-1, SFTPB
25pancreatic serous cystadenocarcinoma10.3GATA4, GATA6
26pseudounicornuate uterus10.3NKX2-1, SFTPB
27slowed nerve conduction velocity, ad10.3EDN1, GATA4, GATA6, ZFPM2
28band keratopathy10.3SFTPB, SFTPC
29endotheliitis10.3
30osteoarthritis10.3NKX2-1, SFTPB, SFTPC
31omphalocele10.2
32aids - neurological complications10.2SFTPB, SFTPC
33hepatitis10.2
34gastroschisis10.2
35thyroiditis10.2
36pulmonary sequestration10.2
37tracheoesophageal fistula10.2
38hartnup disorder10.2NKX2-1, SFTPB, SFTPC
39wolf-hirschhorn syndrome10.2
40diaphragmatic eventration10.2
41polyhydramnios10.2
42lung disease10.2
43donnai-barrow syndrome10.1
44pulmonary hypertension, neonatal10.1
45diaphragmatic hernia 310.1
46gastroesophageal reflux10.1
47intestinal obstruction10.1
48transposition of the great arteries10.1
49wandering spleen10.1
50gingivitis10.1EDN1, SFTPB, SFTPC

Graphical network of the top 20 diseases related to Congenital Diaphragmatic Hernia:



Diseases related to congenital diaphragmatic hernia

Symptoms for Congenital Diaphragmatic Hernia

About this section

Symptoms:

 52
  • congenital diaphragmatic hernia

HPO human phenotypes related to Congenital Diaphragmatic Hernia:

id Description Frequency HPO Source Accession
1 congenital diaphragmatic hernia hallmark (90%) HP:0000776
2 congenital diaphragmatic hernia HP:0000776

Drugs & Therapeutics for Congenital Diaphragmatic Hernia

About this section

Drugs for Congenital Diaphragmatic Hernia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Nitric OxidePhase 458510102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
2Sildenafil citratePhase 4315171599-83-0
3
Citric AcidPhase 4106377-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
4CitrateNutraceuticalPhase 41063
5
Proton pump inhibitorsPhase 31057
Synonyms:
 
PPIs
6
OmeprazolePhase 333173590-58-64594
Synonyms:
( -)-Omeprazole
(-)-Omeprazole
(S)-(-)-Omeprazole
(S)-Omeprazole
119141-89-8
131959-78-9
172964-80-6
2,3,5-Trimethylpyridine/Omeprazole
2-(((3,5-Dimethyl-4-methoxy-2-pyridyl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole
2-({[3,5-dimethyl-4-(methyloxy)pyridin-2-yl]methyl}sulfinyl)-5-(methyloxy)-1H-benzimidazole
5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
73590-58-6
AC-401
AC1L1IIJ
AGI-010
AKOS005066653
AULCER
Antra
Antra MUPS
Audazol
Aulcer
Axagon
BIDD:GT0189
BPBio1_000425
BRD-A55962179-001-04-9
BSPBio_000385
Belmazol
Bio-0888
C07324
CAS-73590-58-6
CCRIS 7099
CHEBI:519601
CHEBI:7772
CHEMBL1503
CID4594
CPD000058847
Ceprandal
D00455
DB00338
DB00736
DM-3458
Danlox
Demeprazol
Desec
Dizprazol
Dudencer
Elgam
Emeproton
Emilok
Epirazole
Erbolin
Esomeprazole
Esomperazole
Esopral
Exter
Gasec
Gastrimut
Gastroloc
Gibancer
H 168-68
H 168/68
H-168/68
H168/68
HMS1528I05
HMS1569D07
HMS2052G17
HMS2090E16
HMS2090F11
HSDB 3575
I06-0705
IDI1_032523
Indurgan
Inhibitron
Inhipump
LS-7629
Lensor
Logastric
Lomac
Losec
Losec, Omesec, Prilosec, Zegerid, Omeprazole
Lucen
MLS000069373
MLS001076112
MLS001424148
Maybridge4_002645
Mepral
Miol
Miracid
MolPort-003-666-741
MolPort-003-807-515
MolPort-003-849-702
Mopral
Morecon
NCGC00016925-01
 
NCGC00016925-02
NCGC00021522-03
NCGC00021522-04
NCGC00021522-05
Nexiam
Nexium
Nexium IV
Nilsec
Nopramin
Nuclosina
O0359
O104_SIGMA
OMEP
OMP
OMZ
Ocid
Olexin
Olit
Omapren
Omebeta
Omebeta 20
Omed
Omegast
Omepradex
Omepral
Omeprazol
Omeprazol [INN-Spanish]
Omeprazole
Omeprazole (JAN/USP/INN)
Omeprazole Pellets
Omeprazole [USAN:INN:BAN:JAN]
Omeprazole delayed-release
Omeprazole magnesium
Omeprazolum
Omeprazolum [INN-Latin]
Omeprazon
Omeprazone
Omeprol
Omesek
Omez
Omezol
Omezolan
Omid
Omisec
Omizac
Ompanyt
Ortanol
Osiren
Ozoken
Paprazol
Parizac
Pepticum
Pepticus
Peptilcer
Prazentol
Prazidec
Prazolit
Prestwick0_000493
Prestwick1_000493
Prestwick2_000493
Prestwick3_000493
Prestwick_808
Prilosec
Prilosec (TN)
Prilosec OTC
Procelac
Proclor
Prysma
Ramezol
Regulacid
Result
S1389_Selleck
SAM001246900
SAN-15
SMR000058847
SPBio_002306
STK623746
Sanamidol
Secrepina
TL8005099
Tedec Ulceral
UNII-KG60484QX9
UPCMLD-DP075
UPCMLD-DP075:001
Ulceral
Ulcesep
Ulcometion
Ulcozol
Ulcsep
Ulsen
Ultop
Ulzol
Victrix
Zefxon
Zegerid
Zepral
Zimor
Zoltum
esomeprazol
omeprazole
7
Pentobarbital1076-74-44737
Synonyms:
(+-)-5-Ethyl-5-(1-methylbutyl)barbituric acid
5-24-09-00168 (Beilstein Handbook Reference)
5-Ethyl-5-(1-methyl-butyl)-pyrimidine-2,4,6-trione
5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
5-Ethyl-5-(1-methylbutyl)barbituric acid
5-Ethyl-5-(1-methylbutyl)malonylurea
5-Ethyl-5-(sec-pentyl)barbituric acid
5-ethyl-2-hydroxy-5-(1-methylbutyl)pyrimidine-4,6(1H,5H)-dione
5-ethyl-5-(1-methylbutyl)barbituric acid
5-ethyl-5-(pentan-2-yl)pyrimidine-2,4,6(1H,3H,5H)-trione
5-ethyl-5-(sec-pentyl)barbituric acid
5-ethyl-5-pentan-2-yl-1,3-diazinane-2,4,6-trione
57-33-0 (mono-hydrochloride salt)
76-74-4
AC1L1IUE
AC1Q2UJM
AKOS000277861
Aethaminalum
BRN 0087067
BSPBio_003305
C07422
CCRIS 7089
CHEBI:7983
CHEMBL448
CID4737
D00499
DB00312
DEA No. 2270
DivK1c_000992
Dorsital
EINECS 200-983-8
Etaminal
Ethaminal
Ethyl-propylmethylcarbinylbarbituric acid
HMS2094E21
HMS503G05
HSDB 3151
IDI1_000992
KBio1_000992
KBio2_002266
KBio2_004834
KBio2_007402
KBio3_002807
KBioGR_001008
KBioSS_002267
LS-24385
 
Mebubarbital
Mebumal
MolPort-001-785-697
MolPort-003-666-760
NCGC00096074-01
NCGC00096074-02
NINDS_000992
NSC 28708
NSC28708
Nebralin
Nembutal
Nembutal (TN)
Nembutal (VAN)
Neodorm
Neodorm (VAN)
Neodorm (new)
Oprea1_143902
Oprea1_775730
Pentabarbital
Pentabarbitone
Pentobarbital
Pentobarbital (USP/INN)
Pentobarbital (VAN)
Pentobarbital [USP:INN]
Pentobarbital calcium
Pentobarbital suppository dosage form
Pentobarbital, Monosodium Salt
Pentobarbitale
Pentobarbitale [DCIT]
Pentobarbitalum
Pentobarbitalum [INN-Latin]
Pentobarbitone
Pentobarbitone (VAN)
Pentobarbiturate
Pentobarbituric acid
Rivadorm
SPBio_002201
SPECTRUM1900006
Sodium Pentobarbital
Spectrum2_001991
Spectrum3_001783
Spectrum4_000574
Spectrum5_001705
Spectrum_001783
UNII-I4744080IR
WLN: T6VMVMV FHJ FY3&1 F2
pentobarbital
8
Ethanol197164-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
9lysineNutraceutical81
10threonineNutraceutical17

Interventional clinical trials:

(show top 50)    (show all 71)
idNameStatusNCT IDPhase
1Nissen and Gastroplasty in Gastroesophageal Reflux Disease (GERD)CompletedNCT00872755Phase 4
2Biologic Versus Synthetic Mesh for Treatment of Paraesophageal HerniaRecruitingNCT02242526Phase 4
3Transoral Incisionless Fundoplication (TIF) Registry Study for Treatment of Gastroesophageal Reflux Disease (GERD)Active, not recruitingNCT01118585Phase 4
4Transoral Incisionless Fundoplication (TIF) Versus Sham for Treatment of Gastroesophageal Reflux Disease (GERD)Active, not recruitingNCT01110811Phase 4
5Chronic Sildenafil for Severe Diaphragmatic HerniaTerminatedNCT00133679Phase 4
6Tracheal Occlusion To Accelerate Lung Growth (TOTAL) Trial for Severe Pulmonary HypoplasiaRecruitingNCT01240057Phase 2, Phase 3
7Rectal and Oral Omeprazole Treatment of Reflux Disease in Infants.RecruitingNCT00226044Phase 3
8Laparoscopic Repair of Giant Hiatal Hernias With Nitinol-framed Lightweight Polytetrafluoroethylene MeshActive, not recruitingNCT01780285Phase 3
9Laparoscopic Lightweight Mesh Repair of Large Hiatal HerniasActive, not recruitingNCT01408108Phase 3
10Usage of Biological Patch Versus Plastic in the Laparoscopic Repair of Hiatal HerniasActive, not recruitingNCT02328248Phase 2, Phase 3
11Randomized EsophyX Versus Sham / Placebo Controlled TIF Trial: The RESPECT StudyActive, not recruitingNCT01136980Phase 3
12Type of Material in Repair of Congenital Diaphragmatic HerniaTerminatedNCT00257946Phase 3
13Fetal Tracheal Occlusion in Severe Diaphragmatic Hernia: a Randomized TrialRecruitingNCT01302977Phase 2
14Fetoscopic Tracheal Balloon Occlusion in Left Diaphragmatic HerniaRecruitingNCT00373438Phase 2
15Percutaneous Endoscopic Tracheal Plug/Unplug for CDHActive, not recruitingNCT00768703Phase 1, Phase 2
16"Nanotechnologies Applied to General Surgery and Emergency Surgery: Buckypaper as a New Fixing Method for Prosthetic Materials for the Treatment of Hernia and Incisional Hernia in Laparotomy and LaparoscopicActive, not recruitingNCT02137018Phase 1, Phase 2
17Early FETO for Severe Congenital Diaphragmatic HerniaNot yet recruitingNCT01731509Phase 2
18Fetal Tracheal Balloon Study in Diaphragmatic HerniaTerminatedNCT00966823Phase 2
19Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)RecruitingNCT02710968Phase 1
20Airway Inflammation in Congenital Diaphragmatic Hernia PatientsCompletedNCT02453750
21Early Childhood Follow-up of Congenital Diaphragmatic Hernia SurvivorsCompletedNCT01029665
22Inflammatory Cytokine Quantification in InfantsCompletedNCT01155830
23Study in Children With the Diagnosis of Congenital Diaphragmatic Hernia (CDH) and Oesophageal Atresia (EA)CompletedNCT02466451
24Genetic Basis of Non Syndromic Congenital Diaphragmatic HerniaCompletedNCT02175264
25Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMOCompletedNCT00371241
26Anesthetic Management in Fetoscopic Surgery and Incidence of ComplicationsCompletedNCT02434926
27Genetic Analysis of Fraser Syndrome and Fryns SyndromeCompletedNCT00032877
28Evaluation of the Follow Me Mode of the AutoLap System - A Feasibility StudyCompletedNCT02326870
29Determination of Lysine Requirement in the Parenterally Fed NeonateCompletedNCT00779753
30PREMAPIV : Intravesical Pressure Variation at Different Bladder Instillation Volumes in Newborn ChildrenCompletedNCT01296724
31Short Esophagus in Type II-IV Hiatus HerniaCompletedNCT01587859
32Use of Strattice Mesh in Paraesophageal Hernia SurgeryCompletedNCT01678157
33Randomized, Prospective Controlled Trial of Paraesophageal Hernia Repair With Small Intestinal Submucosa (SIS)CompletedNCT00272922
34Long-term Outcome of Laparoscopic Hiatal Hernia Repair With or Without Alloderm Mesh at a University HospitalCompletedNCT01776827
35Follow-up of Patients Operated Upon for Type II-IV Hiatal HerniaCompletedNCT01606449
36Necessity of Esophageal Dissection During Laparoscopic FundoplicationCompletedNCT00287612
37Laparoscopy Versus Clinical Follow up to Detect Diaphragm InjuryCompletedNCT01044550
38Prospective Study of Ventral Hernia RepairCompletedNCT00894582
39Diaphragmatic Hernia Research & Exploration, Advancing Molecular ScienceRecruitingNCT00950118
40Gene Mutations and Rescue in Human Congenital Diaphragmatic HerniaRecruitingNCT01098929
41Fetal Endotracheal Occlusion (FETO) in Severe and Extremely Severe Congenital Diaphragmatic HerniaRecruitingNCT00881660
42Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood GasesRecruitingNCT01467245
43Randomized Control Trial of Fetoscopic Endoluminal Tracheal Occlusion With a Balloon Versus Expectant Management During Pregnancy in Fetuses With Left Sided Congenital Diaphragmatic Hernia and Moderate Pulmonary Hypoplasia.RecruitingNCT00763737
44Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic HerniaRecruitingNCT02549820
45Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO)RecruitingNCT02530073
46Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Congenital Diaphragm HerniaRecruitingNCT02596802
47CDH - Optimisation of Neonatal VentilationRecruitingNCT02849054
48Genetic Analysis of Congenital Diaphragmatic DisordersRecruitingNCT01243229
49Pregnancy Environment and Newborn MalformationsRecruitingNCT01613638
50Circulatory Changes During Venovenous (VV)- and Venoarterial (VA) Extracorporeal Membrane Oxygenation (ECMO)RecruitingNCT00622492

Search NIH Clinical Center for Congenital Diaphragmatic Hernia


Cochrane evidence based reviews: hernia, diaphragmatic

Genetic Tests for Congenital Diaphragmatic Hernia

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Genetic tests related to Congenital Diaphragmatic Hernia:

id Genetic test Affiliating Genes
1 Congenital Diaphragmatic Hernia25 23

Anatomical Context for Congenital Diaphragmatic Hernia

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MalaCards organs/tissues related to Congenital Diaphragmatic Hernia:

34
Lung, Heart, Liver, Fetal lung, Small intestine, Testes, Endothelial

Animal Models for Congenital Diaphragmatic Hernia or affiliated genes

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MGI Mouse Phenotypes related to Congenital Diaphragmatic Hernia:

39 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.1ALDH1A2, EDN1, FREM1, GATA4, GATA6, NR2F2
2MP:00053819.0EDN1, EFNB1, FREM1, GATA4, LRP2, NKX2-1
3MP:00053829.0ALDH1A2, EDN1, EFNB1, FREM1, LRP2, NIPBL
4MP:00030129.0EFNB1, GATA4, LRP2, NKX2-1, NR2F2, SFTPC
5MP:00053918.9ALDH1A2, EFNB1, FREM1, LRP2, NIPBL, NR2F2
6MP:00053678.6ALDH1A2, EDN1, FGF7, FREM1, LRP2, PORCN
7MP:00053848.6ALDH1A2, EFNB1, GATA4, GATA6, LRP2, NIPBL
8MP:00053888.5ALDH1A2, EFNB1, FREM1, GATA4, GATA6, LRP2
9MP:00053718.4ALDH1A2, EFNB1, FREM1, GATA4, GATA6, LRP2
10MP:00028738.2ALDH1A2, EDN1, FREM1, GATA4, GATA6, NIPBL
11MP:00053808.2ALDH1A2, EDN1, EFNB1, GATA4, GATA6, LRP2
12MP:00053908.1ALDH1A2, EDN1, EFNB1, FREM1, GATA4, LRP2
13MP:00053857.9ALDH1A2, EDN1, GATA4, GATA6, LRP2, NIPBL
14MP:00053897.9EFNB1, FGF7, FREM1, GATA4, GATA6, LRP2
15MP:00053797.6ALDH1A2, EDN1, EFNB1, FREM1, GATA4, HOMER2
16MP:00036317.5ALDH1A2, EDN1, EFNB1, FGF7, FREM1, GATA4
17MP:00053767.4ALDH1A2, EDN1, EFNB1, FGF7, GATA4, GATA6
18MP:00053787.2ALDH1A2, EDN1, EFNB1, FREM1, GATA4, GATA6
19MP:00107687.1ALDH1A2, EDN1, EFNB1, FREM1, GATA4, GATA6

Publications for Congenital Diaphragmatic Hernia

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Articles related to Congenital Diaphragmatic Hernia:

(show top 50)    (show all 716)
idTitleAuthorsYear
1
Addressing the causes of late mortality in infants with congenital diaphragmatic hernia. (27624564)
2016
2
Sphingolipids in Congenital Diaphragmatic Hernia; Results from an International Multicenter Study. (27159222)
2016
3
Improving the Prediction of Neonatal Outcomes in Isolated Left-Sided Congenital Diaphragmatic Hernia by Direct and Indirect Sonographic Assessment of Liver Herniation. (27208195)
2016
4
Growth Patterns of Fetal Lung Volumes in Healthy Fetuses and Fetuses With Isolated Left-Sided Congenital Diaphragmatic Hernia. (27091916)
2016
5
Fetal stomach and gallbladder in contact with the bladder wall is a common ultrasound sign of stomach-down left congenital diaphragmatic hernia. (27663268)
2016
6
Polygenic Causes of Congenital Diaphragmatic Hernia Produce Common Lung Pathologies. (27565037)
2016
7
Pulmonary capillary hemangiomatosis in a neonate with congenital diaphragmatic hernia. (25678439)
2015
8
Short-Term Outcomes and Medical and Surgical Interventions in Infants with Congenital Diaphragmatic Hernia. (25825963)
2015
9
Improved mortality rate for congenital diaphragmatic hernia in the modern era of management: 15year experience in a single institution. (25840055)
2015
10
Minimally invasive surgery for congenital diaphragmatic hernia: a meta-analysis. (26438082)
2015
11
Making Meaning of Pumping for Mothers of Infants With Congenital Diaphragmatic Hernia. (25851118)
2015
12
Growth Assessment and the Risk of Growth Retardation in Congenital Diaphragmatic Hernia: A Long-Term Follow-Up Study from the Japanese Congenital Diaphragmatic Hernia Study Group. (26509310)
2015
13
Expanded intrathoracic space in fetal cases of isolated congenital diaphragmatic hernia contributes to disparity between percent predicted lung volume and observed to expected total lung volume. (25297651)
2014
14
Atypical presentation of congenital diaphragmatic hernia. (25378787)
2014
15
Prenatal imaging of a fetus with the rare combination of a right congenital diaphragmatic hernia and a giant omphalocele. (25059273)
2014
16
B-type natriuretic peptide: prognostic marker in congenital diaphragmatic hernia. (25188741)
2014
17
Splenic torsion after congenital diaphragmatic hernia repair: case report and review of the literature. (23480945)
2013
18
Fetal production of growth factors and inflammatory mediators predicts pulmonary hypertension in congenital diaphragmatic hernia. (23770923)
2013
19
Long-term maturation of congenital diaphragmatic hernia treatment results: toward development of a severity-specific treatment algorithm. (23989050)
2013
20
Late-presenting congenital diaphragmatic hernia in children: the experience of single institution in Korea. (23918563)
2013
21
Antenatally diagnosed congenital diaphragmatic hernia in Singapore: a five-year series. (24005449)
2013
22
Functional residual capacity (FRC) and lung clearance index (LCI) in mechanically ventilated infants: application in the newborn with congenital diaphragmatic hernia (CDH). (23895954)
2013
23
Timing and expression of the angiopoietin-1-Tie-2 pathway in murine lung development and congenital diaphragmatic hernia. (22917924)
2013
24
Increased contractility and impaired relaxation of the left pulmonary artery in a rabbit model of congenital diaphragmatic hernia. (23269641)
2013
25
Decreased pulmonary c-Cbl expression and tyrosine phosphorylation in the nitrofen-induced rat model of congenital diaphragmatic hernia. (23143077)
2013
26
Congenital diaphragmatic hernia. (23114974)
2012
27
Stabilisation of cardiopulmonary function in newborns with congenital diaphragmatic hernia using lung function parameters and hemodynamic management. (22782443)
2012
28
Recent advances in the management of congenital diaphragmatic hernia. (22491491)
2012
29
Regenerative medicine for congenital diaphragmatic hernia: regeneration for repair. (23114980)
2012
30
Using serial oxygenation index as an objective predictor of survival for antenatally diagnosed congenital diaphragmatic hernia. (23163987)
2012
31
Perinatal outcome of congenital diaphragmatic hernia in an Australian tertiary hospital. (22145569)
2012
32
Influence of fetal stabilization on postnatal status of patients with congenital diaphragmatic hernia. (20842386)
2011
33
Evaluation of esophageal motility and reflux in children treated for congenital diaphragmatic hernia with the use of combined multichannel intraluminal impedance and pH monitoring. (22008321)
2011
34
Congenital diaphragmatic hernia: still a moving target. (21463974)
2011
35
Congenital diaphragmatic hernia in Smith-Magenis syndrome: a possible locus at chromosome 17p11.2. (21965155)
2011
36
Physical activity, fitness, and dyspnea perception in children with congenital diaphragmatic hernia. (21520442)
2011
37
Patch repair is an independent predictor of morbidity and mortality in congenital diaphragmatic hernia. (21590477)
2011
38
Learning curve for lung area to head circumference ratio measurement in fetuses with congenital diaphragmatic hernia. (20131334)
2010
39
Mortality in infants with congenital diaphragmatic hernia: a study of the United States National Database. (20147959)
2010
40
Congenital diaphragmatic hernia in Lowe syndrome: a rare association? (20823704)
2010
41
Management of prenatally diagnosed congenital diaphragmatic hernia. (19884051)
2010
42
Perforated ulcer mimicking a spontaneous pneumothorax in a patient with congenital diaphragmatic hernia. (19385305)
2009
43
Congenital diaphragmatic hernia: outcome review of 2,173 surgical repairs in US infants. (19727769)
2009
44
Impaired somatic growth and delayed lung development in infants with congenital diaphragmatic hernia--evidence from a 10-year, single center prospective follow-up study. (19573653)
2009
45
Pulmonary hypertension in human newborns with congenital diaphragmatic hernia is associated with decreased vascular expression of nitric-oxide synthase. (16456243)
2006
46
Congenital diaphragmatic hernia: is 15q26.1-26.2 a candidate locus? (15057983)
2004
47
Upregulated expression of EGF and TGF-alpha in the proximal respiratory epithelium in the human hypoplastic lung in congenital diaphragmatic hernia. (14714133)
2004
48
Wandering spleen presenting as duodenal obstruction after repair of congenital diaphragmatic hernia. (9434030)
1997
49
Coexisting left congenital diaphragmatic hernia and esophageal atresia with tracheoesophageal fistula: successful management in a premature neonate. (8811578)
1996
50
Congenital diaphragmatic hernia and intrathoracic intestinal volvulus. (8292583)
1993

Variations for Congenital Diaphragmatic Hernia

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Copy number variations for Congenital Diaphragmatic Hernia from CNVD:

6 (show top 50)    (show all 94)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1158571119957963119994447DeletionHSD3B2Congenital diaphragmatic hernia
2235971171936289171970634InDNM3Congenital diaphragmatic hernia
3277401212100000222100000DeletionDISP1Congenital diaphragmatic hernia
4277441212100000222100000DeletionHLXCongenital diaphragmatic hernia
5277541212100000225100000DeletionCongenital diaphragmatic hernia
6285221223073839225318623DeletionC1orf65Congenital diaphragmatic hernia
7285231223073839225318623DeletionCAPN2Congenital diaphragmatic hernia
8285241223073839225318623DeletionCAPN8Congenital diaphragmatic hernia
9285251223073839225318623DeletionDEGS1Congenital diaphragmatic hernia
10285261223073839225318623DeletionDISP1Congenital diaphragmatic hernia
11285271223073839225318623DeletionDNAH14Congenital diaphragmatic hernia
12285281223073839225318623DeletionFBXO28Congenital diaphragmatic hernia
13285291223073839225318623DeletionMIR320B2Congenital diaphragmatic hernia
14285301223073839225318623DeletionNVLCongenital diaphragmatic hernia
15285311223073839225318623DeletionSUSD4Congenital diaphragmatic hernia
16285321223073839225318623DeletionTLR5Congenital diaphragmatic hernia
17285331223073839225318623DeletionTP53BP2Congenital diaphragmatic hernia
18285341223073839225318623DeletionWDR26Congenital diaphragmatic hernia
193558816513734565218480InCACHD1Congenital diaphragmatic hernia
203558916513734565218480InRAVER2Congenital diaphragmatic hernia
214997811112347267134927114DerCongenital diaphragmatic hernia
2252746111916801232271202DerCongenital diaphragmatic hernia
2359704117727054077431584InAQP11Congenital diaphragmatic hernia
2459705117727054077431584InCLNS1ACongenital diaphragmatic hernia
2559706117727054077431584InRSF1Congenital diaphragmatic hernia
2664289121260000014800000DeletionRAIG1Congenital diaphragmatic hernia
276907612530000010000000DeletionRBP5Congenital diaphragmatic hernia
2879371137066649171594524InATXN8OSCongenital diaphragmatic hernia
2979372137066649171594524InKLHL1Congenital diaphragmatic hernia
3079373137066649171594524InSCA8Congenital diaphragmatic hernia
3185160143987520640301762DeletionFBXO33Congenital diaphragmatic hernia
3293300155079175850833347DeletionUSP50Congenital diaphragmatic hernia
3393301155079175850833347DeletionUSP8Congenital diaphragmatic hernia
3493579155580000065300000DeletionCongenital diaphragmatic hernia
3594339156530000076100000DeletionCongenital diaphragmatic hernia
3694505156754004268049656DeletionAAGABCongenital diaphragmatic hernia
3794506156754004268049656DeletionC15orf61Congenital diaphragmatic hernia
3894507156754004268049656DeletionIQCHCongenital diaphragmatic hernia
3994508156754004268049656DeletionMAP2K5Congenital diaphragmatic hernia
4095359157560010875648132InCOMMD4Congenital diaphragmatic hernia
4195360157560010875648132InNEIL1Congenital diaphragmatic hernia
4295413157610000079500000DeletionCRABP1Congenital diaphragmatic hernia
4395695157950000083000000DeletionCongenital diaphragmatic hernia
4495710157950000083000000MicrodeletionsAP3B2Congenital diaphragmatic hernia
4595711157950000083000000MicrodeletionsCPEB1Congenital diaphragmatic hernia
4695712157950000083000000MicrodeletionsHDGFRP3Congenital diaphragmatic hernia
4795713157950000083000000MicrodeletionsHOMER2Congenital diaphragmatic hernia
4896233158690000096300000DeletionCongenital diaphragmatic hernia
4996719159210000096300000DeletionCongenital diaphragmatic hernia
50973501616300000GainCongenital diaphragmatic hernia

Expression for genes affiliated with Congenital Diaphragmatic Hernia

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Search GEO for disease gene expression data for Congenital Diaphragmatic Hernia.

Pathways for genes affiliated with Congenital Diaphragmatic Hernia

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Pathways related to Congenital Diaphragmatic Hernia according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.8GATA6, SFTPB, SFTPC

GO Terms for genes affiliated with Congenital Diaphragmatic Hernia

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Cellular components related to Congenital Diaphragmatic Hernia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lamellar bodyGO:004259910.1SFTPB, SFTPC
2clathrin-coated endocytic vesicleGO:004533410.0SFTPB, SFTPC
3multivesicular body lumenGO:00974869.7SFTPB, SFTPC

Biological processes related to Congenital Diaphragmatic Hernia according to GeneCards Suite gene sharing:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of cardioblast differentiationGO:005189110.8GATA4, GATA6
2Type II pneumocyte differentiationGO:006051010.8GATA6, NKX2-1
3Clara cell differentiationGO:006048610.8GATA6, NKX2-1
4outflow tract septum morphogenesisGO:000314810.8GATA6, ZFPM2
5positive regulation of cardiac muscle cell proliferationGO:006004510.8GATA6, ZFPM2
6intestinal epithelial cell differentiationGO:006057510.8GATA4, GATA6
7lung saccule developmentGO:006043010.7GATA6, NKX2-1
8negative regulation of female gonad developmentGO:200019510.7WT1, ZFPM2
9embryonic digestive tract developmentGO:004856610.6ALDH1A2, STRA6
10uterus morphogenesisGO:006103810.6NIPBL, STRA6
11cardiac muscle tissue developmentGO:004873810.5ALDH1A2, GATA6, ZFPM2
12cellular response to gonadotropin stimulusGO:007137110.5GATA6, WT1
13anatomical structure formation involved in morphogenesisGO:004864610.4GATA4, NKX2-1
14neural crest cell developmentGO:001403210.4ALDH1A2, EDN1
15adrenal gland developmentGO:003032510.4STRA6, WT1
16diaphragm developmentGO:006053910.4STRA6, WT1
17ventricular septum developmentGO:000328110.3GATA4, LRP2, STRA6
18response to vitamin AGO:003318910.3ALDH1A2, GATA4
19cellular protein metabolic processGO:004426710.3GATA6, SFTPB, SFTPC
20positive regulation of male gonad developmentGO:200002010.3WT1, ZFPM2
21animal organ morphogenesisGO:000988710.2ELN, NKX2-1, SFTPB
22in utero embryonic developmentGO:000170110.2EDN1, GATA6, NR2F2, ZFPM2
23kidney developmentGO:000182210.2ALDH1A2, STRA6, WT1
24lung developmentGO:003032410.1ALDH1A2, NKX2-1, STRA6, ZFPM2
25male gonad developmentGO:000858410.1GATA4, GATA6, WT1
26respiratory gaseous exchangeGO:000758510.0EDN1, ELN, SFTPB, SFTPC
27forebrain developmentGO:00309009.8ALDH1A2, LRP2, NKX2-1, NR2F2
28negative regulation of transcription, DNA-templatedGO:00458929.2GATA6, NIPBL, NKX2-1, NR2F2, WT1, ZFPM2
29positive regulation of transcription, DNA-templatedGO:00458939.2FGF7, GATA4, GATA6, NKX2-1, NR2F2, WT1
30heart developmentGO:00075079.1EDN1, LRP2, NIPBL, STRA6, WT1, ZFPM2
31positive regulation of transcription from RNA polymerase II promoterGO:00459448.7EDN1, GATA4, GATA6, NIPBL, NKX2-1, WT1
32negative regulation of transcription from RNA polymerase II promoterGO:00001228.4EDN1, GATA6, NIPBL, NKX2-1, NR2F2, WT1

Molecular functions related to Congenital Diaphragmatic Hernia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II transcription factor bindingGO:000108510.3GATA4, GATA6, ZFPM2
2transcription regulatory region DNA bindingGO:00442129.7GATA4, GATA6, NKX2-1, WT1
3sequence-specific DNA bindingGO:00435659.4GATA4, GATA6, NKX2-1, NR2F2, WT1

Sources for Congenital Diaphragmatic Hernia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet