MCID: CNG023
MIFTS: 31

Congenital Fibrosarcoma malady

Cancer diseases, Rare diseases, Bone diseases categories
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Summaries for Congenital Fibrosarcoma

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MalaCards based summary: Congenital Fibrosarcoma, also known as infantile fibrosarcoma, is related to fibrosarcoma and congenital mesoblastic nephroma. An important gene associated with Congenital Fibrosarcoma is NTRK3 (neurotrophic tyrosine kinase, receptor, type 3). The compounds vegf and imatinib have been mentioned in the context of this disorder. Affiliated tissues include tongue and heart.

Aliases & Classifications for Congenital Fibrosarcoma

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Congenital Fibrosarcoma, Aliases & Descriptions:

Name: Congenital Fibrosarcoma 8 10 62
 
Infantile Fibrosarcoma 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Bone diseases


External Ids:

Disease Ontology8 DOID:8418
SNOMED-CT57 403996004, 52040006
NCIt39 C4244

Related Diseases for Congenital Fibrosarcoma

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Diseases in the Fibrosarcoma family:

congenital fibrosarcoma Adult Fibrosarcoma

Diseases related to Congenital Fibrosarcoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 32)
idRelated DiseaseScoreTop Affiliating Genes
1fibrosarcoma31.5NTRK3, ETV6
2congenital mesoblastic nephroma30.5ETV6, NTRK3
3hemangioma10.2
4mesoblastic nephroma10.2
5sacrococcygeal teratoma10.1
6wilms tumor10.1
7fibroma10.1
8spindle cell lipoma10.1
9myofibroma10.1
10urticaria pigmentosa10.1
11cellular congenital mesoblastic nephroma10.1
12fasciitis10.1
13lipoma10.1
14rhabdomyosarcoma10.1
15sarcoma10.1
16urticaria10.1
17teratoma10.1
18calcified aponeurotic fibroma10.1
19bone marrow cancer10.0NTRK3, ETV6
20leukemia10.0
21fibrous histiocytoma10.0
22choroiditis10.0
23chondroma10.0
24histiocytoma10.0
25intestinal obstruction10.0
26peritonitis10.0
27enchondroma10.0
28infantile myofibromatosis10.0
29chronic myeloid leukemia10.0NTRK3, ETV6
30breast cancer10.0NTRK3, ETV6
31acute leukemia10.0NTRK3, ETV6
32myeloid leukemia9.9NTRK3, ETV6

Graphical network of the top 20 diseases related to Congenital Fibrosarcoma:



Diseases related to congenital fibrosarcoma

Symptoms for Congenital Fibrosarcoma

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Drugs & Therapeutics for Congenital Fibrosarcoma

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Drug clinical trials:

Search ClinicalTrials for Congenital Fibrosarcoma

Search NIH Clinical Center for Congenital Fibrosarcoma

Genetic Tests for Congenital Fibrosarcoma

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Anatomical Context for Congenital Fibrosarcoma

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MalaCards organs/tissues related to Congenital Fibrosarcoma:

32
Tongue, Heart

Animal Models for Congenital Fibrosarcoma or affiliated genes

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Publications for Congenital Fibrosarcoma

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Articles related to Congenital Fibrosarcoma:

(show top 50)    (show all 58)
idTitleAuthorsYear
1
Congenital fibrosarcoma of the bowel: Sonographic description of a rare case of neonatal intestinal obstruction. (24281989)
2013
2
Congenital fibrosarcoma and history of prenatal exposure to petroleum derivatives. (22945410)
2012
3
Congenital fibrosarcoma of the ileum: case report with molecular confirmation and literature review. (21355680)
2011
4
A giant congenital fibrosarcoma of the leg. (20442675)
2010
5
Congenital fibrosarcoma of the chest wall: report of a case. (21430833)
2010
6
Congenital fibrosarcoma with a novel complex 3-way translocation t(12;15;19) and unusual histologic features. (18657299)
2008
7
Unilateral mosaic cutaneous vascular lesions, enchondroma, multiple soft tissue chondromas and congenital fibrosarcoma--a variant of Maffucci syndrome? (18429781)
2008
8
Congenital fibrosarcoma as cause for fetal anemia: prenatal diagnosis and in utero treatment. (19018145)
2008
9
Congenital fibrosarcoma simulating congenital hemangioma. (18304187)
2008
10
Congenital fibrosarcoma of the upper extremity--a case report and review of literature. (16366098)
2005
11
Combined prenatal ultrasound and magnetic resonance imaging in an extensive congenital fibrosarcoma: a case report and review of the literature. (15980638)
2005
12
Congenital fibrosarcoma with metastasis in a fetus. (15022058)
2004
13
Management of extensive congenital fibrosarcoma with preoperative chemotherapy. (15456453)
2004
14
Congenital fibrosarcoma of the jejunum in a premature infant with meconium peritonitis. (12776248)
2003
15
Chemotherapy alone for the treatment of congenital fibrosarcoma: is surgery always needed? (12555264)
2003
16
Cellular mesoblastic nephroma: morphologic, cytogenetic and molecular links with congenital fibrosarcoma. (12650516)
2003
17
Regression of congenital fibrosarcoma to hemangiomatous remnant with histological and genetic findings. (12406191)
2002
18
The detection of Tel-TrkC chimeric transcripts is more specific than TrkC immunoreactivity for the diagnosis of congenital fibrosarcoma. (11169520)
2001
19
Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia. (10775267)
2000
20
Molecular detection of the ETV6-NTRK3 gene fusion differentiates congenital fibrosarcoma from other childhood spindle cell tumors. (10895816)
2000
21
Prenatal sonographic appearance of congenital fibrosarcoma. (9608374)
1998
22
Congenital fibrosarcoma of the upper extremity. (9734437)
1998
23
A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma. (9462753)
1998
24
Congenital palmar nodule in an infant. Congenital fibrosarcoma. (9192424)
1997
25
Intrathoracic congenital fibrosarcoma. A case report. (7608883)
1995
26
Congenital fibrosarcoma masquerading as lymphatic malformation: report of two cases. (7722837)
1995
27
Are infantile myofibromatosis, congenital fibrosarcoma and congenital haemangiopericytoma histogenetically related? (7713484)
1995
28
Congenital fibrosarcoma. Report of three cases. (8772821)
1995
29
Pediatric case of the day. Congenital fibrosarcoma (CFS). (7899610)
1995
30
Limb congenital fibrosarcoma: report of two cases and review of the literature. (8292522)
1993
31
Consistent numerical chromosome aberrations in congenital fibrosarcoma. (8453601)
1993
32
Ultrastructural, immunocytochemical, and cytogenetic characterization of a large congenital fibrosarcoma. (1524466)
1992
33
Deletion of part of the short arm of chromosome 17 in a congenital fibrosarcoma. (2204476)
1990
34
Cytogenetic investigation of a case of congenital fibrosarcoma. (2731143)
1989
35
Congenital fibrosarcoma. (3612464)
1987
36
Congenital fibrosarcoma of the forearm. A case report. (3957990)
1986
37
Congenital fibrosarcoma: a congenital fibrous histiocytoma. (3035524)
1986
38
Complete response of congenital fibrosarcoma to chemotherapy. (2878294)
1986
39
Congenital fibrosarcoma. Preoperative chemotherapy and conservative surgery. (3755646)
1986
40
Congenital fibrosarcoma of the tongue. A case report. (6674897)
1983
41
Congenital fibrosarcoma of the axilla in an infant. (6675544)
1983
42
Congenital fibrosarcoma of the tongue. (7064583)
1982
43
Case report 149. Infantile congenital fibrosarcoma of humerus. (7268465)
1981
44
Congenital fibrosarcoma: presence of a histiocytic component. (7388769)
1980
45
Congenital fibrosarcoma metastatic to the choroid. (443333)
1979
46
Pancreaticoduodenectomy in the treatment of congenital fibrosarcoma of the duodenum. (1185470)
1975
47
Congenital fibrosarcoma of the thoracolumbar region. (4607996)
1974
48
Ultrastructure of congenital fibrosarcoma. (5483658)
1970
49
Congenital fibrosarcoma. (13095275)
1953
50
Congenital fibrosarcoma; report of a case in a newborn infant. (14818531)
1951

Variations for Congenital Fibrosarcoma

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Expression for genes affiliated with Congenital Fibrosarcoma

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Expression patterns in normal tissues for genes affiliated with Congenital Fibrosarcoma

Search GEO for disease gene expression data for Congenital Fibrosarcoma.

Pathways for genes affiliated with Congenital Fibrosarcoma

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Compounds for genes affiliated with Congenital Fibrosarcoma

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Sources:
44Novoseek, 50PharmGKB, 11DrugBank
See all sources

Compounds related to Congenital Fibrosarcoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1vegf449.3NTRK3, ETV6
2imatinib44 50 1111.0NTRK3, ETV6

GO Terms for genes affiliated with Congenital Fibrosarcoma

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Cellular components related to Congenital Fibrosarcoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi apparatusGO:0057949.1GOLGA6B, GOLGA6A

Products for genes affiliated with Congenital Fibrosarcoma

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  • Antibodies
  • Proteins
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Sources for Congenital Fibrosarcoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet