MCID: CNG023
MIFTS: 34

Congenital Fibrosarcoma malady

Categories: Cancer diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways Drugs

Aliases & Classifications for Congenital Fibrosarcoma

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Aliases & Descriptions for Congenital Fibrosarcoma:

Name: Congenital Fibrosarcoma 11 13
 
Infantile Fibrosarcoma 11 68

Classifications:

MalaCards categories:
Global: Cancer diseases, Rare diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology11 DOID:8418
SNOMED-CT62 403996004, 52040006
NCIt45 C4244

Summaries for Congenital Fibrosarcoma

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MalaCards based summary: Congenital Fibrosarcoma, also known as infantile fibrosarcoma, is related to fibrosarcoma and ceroid lipofuscinosis, neuronal, 9. An important gene associated with Congenital Fibrosarcoma is ETV6 (ETS Variant 6), and among its related pathways are Neurotrophic factor-mediated Trk receptor signaling and Aurora B signaling. Affiliated tissues include tongue and heart, and related mouse phenotypes are cardiovascular system and mortality/aging.

Related Diseases for Congenital Fibrosarcoma

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Diseases in the Fibrosarcoma family:

Adult Fibrosarcoma congenital fibrosarcoma

Diseases related to Congenital Fibrosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 82)
idRelated DiseaseScoreTop Affiliating Genes
1fibrosarcoma10.5
2ceroid lipofuscinosis, neuronal, 910.4ETV6, NTRK3
3cocaine abuse10.4ETV6, NTRK3
4exudative glomerulonephritis10.3ETV6, NTRK3
5xq12-q13.3 duplication syndrome10.3ACTC1, DES
6bronchiolo-alveolar adenocarcinoma10.3ETV6, NTRK3
7intravascular fasciitis10.2ACTC1, DES
8pura syndrome10.2ACTC1, DES
9pleuropulmonary blastoma type 210.2ACTC1, DES
10lymphangiomatosis10.2ACTC1, VIM
11myxoid liposarcoma of the ovary10.2ACTC1, VIM
12iridogoniodysgenesis and skeletal anomalies10.1ACTC1, VIM
13parovarian cyst10.1ACTC1, DES
14skin sarcoma10.1ACTC1, VIM
15vulvar alveolar soft part sarcoma10.1ACTC1, VIM
16eccrine papillary adenoma10.1ACTC1, VIM
17malignant peritoneal solitary fibrous tumor10.1ACTC1, VIM
18harding ataxia10.1DES, VIM
19absence of fingerprints congenital milia10.1DES, VIM
20lymphocytic vasculitis10.1DES, VIM
21pineal parenchymal tumor of intermediate differenciation10.1ACTC1, VIM
22pancreatic delta cell neoplasm10.1DES, VIM
23ovarian cystadenocarcinoma10.1ACTC1, VIM
24anterograde amnesia10.1DES, VIM
25monophasic synovial sarcoma10.1DES, VIM
26vascular hemostatic disease10.1ACTC1, VIM
27orbit rhabdomyosarcoma10.1ACTC1, DES
28bartholin's gland benign neoplasm10.1DES, VIM
29malignant adenofibroma10.1DES, VIM
30sclerosing liposarcoma10.1DES, VIM
31focal chorioretinitis10.0DES, VIM
32paranasal sinus cancer, adult10.0ACTC1, VIM
33longitudinal vaginal septum10.0ACTC1, DES
34extraosseous osteosarcoma10.0ETV6, NTRK3
35angora hair nevus10.0DES, VIM
36dens in dente and palatal invaginations10.0ACTC1, VIM
37gangliocytoma10.0DES, VIM
38glioma susceptibility 110.0ACTC1, VIM
39emerinopathy10.0DES, VIM
40meige syndrome10.0ACTC1, DES
41atrial standstill9.9ETV6, NTRK3
42fibrosing mediastinitis9.9DES, VIM
43lipoatrophy with diabetes, leukomelanodermic papules, liver steatosis, and hypertrophic cardiomyopathy9.9ACTC1, VIM
44renal tubular acidosis, distal, autosomal recessive9.9DES, VIM
45polyomavirus allograft nephropathy9.8ACTC1, NTRK3, VIM
46advanced sleep-phase syndrome, familial, 29.8DES, VIM
47adult astrocytic tumour9.8ACTC1, VIM
48hemangioma9.7
49skin lipoma9.7ACTC1, DES, VIM
50lymphangiosarcoma9.7ACTC1, DES, VIM

Graphical network of the top 20 diseases related to Congenital Fibrosarcoma:



Diseases related to congenital fibrosarcoma

Symptoms & Phenotypes for Congenital Fibrosarcoma

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MGI Mouse Phenotypes related to Congenital Fibrosarcoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053858.4ACTC1, DES, ETV6, NTF3, NTRK3, VIM
2MP:00107686.7ACTC1, DES, ETV6, NTF3, NTRK3, UBE2I

Drugs & Therapeutics for Congenital Fibrosarcoma

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Drugs for Congenital Fibrosarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
IfosfamideapprovedPhase 23913778-73-23690
Synonyms:
(+-)-Ifosfamid
(+-)-Ifosphamide
(+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
(D,L)-Ifosfamide
(R,S)-Ifosphamide
(R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd
2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis( 2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI)
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
3,} 2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2- oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
36341-88-5
3778-73-2
84711-20-6
A 4942
AB00513932
AC-2113
AC1L1GHW
ASTA Z 4942
Ambap3778-73-2
Asta Z 4942
BPBio1_000865
BRN 0611835
BSPBio_000785
C07047
CAS-3778-73-2
CCRIS 352
CHEBI:5864
CHEMBL1024
CID3690
Cyfos
D00343
D007069
DB01181
EINECS 223-237-3
HMS1570H07
HMS2090M12
HMS2093N07
HSDB 7023
Holoxan
Holoxan 1000
I-Phosphamide
I06-0494
IFEX (TN)
Ifex
Ifosfamid
Ifosfamida
Ifosfamida [INN-Spanish]
Ifosfamide (JAN/USP/INN)
 
Ifosfamide Sterile
Ifosfamide [USAN:INN:BAN:JAN]
Ifosfamidum
Ifosfamidum [INN-Latin]
Ifosphamide
Ifsofamide
Iphosphamid
Iphosphamid(e)
Iphosphamide
Iso Endoxan
Iso-Endoxan
Isoendoxan
Isofosfamide
Isophosphamide
Isosfamide
LS-102
LS-99799
MJF 9325
MJF-9325
MLS002154021
Mitoxana
Mitoxana, Ifex, Ifosfamide
MolPort-003-666-704
N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide
N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine
NCGC00016639-01
NCGC00179435-01
NCI-C01638
NCI60_000233
NPFAPI-04
NSC 109,724
NSC 109724
NSC-109,724
NSC-109724
NSC109,724
NSC109724
Naxamide
Prestwick0_000833
Prestwick1_000833
Prestwick2_000833
Prestwick3_000833
S1302_Selleck
SMR001233348
SPBio_002706
STL058690
UNII-UM20QQM95Y
WLN: T6NPOTJ AM2G BO B2G
Z 4942
Z-4942
Z4942
ifosfamide
isosfamide
{3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,
2
DactinomycinapprovedPhase 24850-76-02019, 457193
Synonyms:
(- )-actinomycin d
(-)-actinomycin d
-pentone
01815_FLUKA
1H-Pyrrolo(2,1-1)-(1,4,7,10,13)oxatetraazacyclohexadecine
2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-I)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
50-76-0
A1410_SIGMA
A4262_SIGMA
A9415_SIGMA
AC1L1CQX
AC1L9W52
ACT
ACT D
ACTINOMYCIN D
ACTINOMYCIN D AMP
ACTINOMYCIN-D
ACTO-D
ACon0_000471
ACon1_001004
AD
AD (VAN)
AI3-26374
ActD
Actactinomycin A IV
Actactinomycin a Iv
Actinomycin 11 Cosmegen
Actinomycin 11 cosmegen
Actinomycin 7
Actinomycin A IV
Actinomycin Aiv
Actinomycin C (sub1)
Actinomycin C(sub1)
Actinomycin C1
Actinomycin D
Actinomycin D (JP15)
Actinomycin D deriv. of 3H-phenoxaocardazine
Actinomycin D, sodium deoxyribonucleic acid complex
Actinomycin I
Actinomycin I (sub1)
Actinomycin I(sub 1)
Actinomycin I(sub1)
Actinomycin I1
Actinomycin IV
Actinomycin Iv
Actinomycin X 1
Actinomycin X1
Actinomycin iv
Actinomycin-(threo-val-pro-sar-meval)
Actinomycin-?IV
Actinomycin-[threo-val-pro-sar-meval]
Actinomycindioic D Acid, Dilactone
Actinomycindioic D acid, dilactone
Acto-D
Antibiotic From Streptomyces Parvullus
Antibiotic from Streptomyces parvullus
BCBcMAP01_000155
BRD-A42383464-001-02-2
Bio1_000342
Bio1_000831
Bio1_001320
C06770
C1
C62H86N12O16
CBiol_002056
CCRIS 9
CHEBI:123721
CHEBI:27666
CHEMBL1554
CHEMBL427947
CID2019
 
CID457193
COSMEGEN (TN)
CPD000469227
Chounghwamycin B
Cosmegen
D Actinomycin
D00214
DACTINOMYCIN
DB00970
DVA-DPR-SAR-MVA-(c1)DTH-PXZ-(c11)DTH-DVA-DPR-SAR-MVA
Dactinomicina
Dactinomicina [INN-Spanish]
Dactinomycin
Dactinomycin (USP)
Dactinomycin D
Dactinomycin [USAN:BAN]
Dactinomycine
Dactinomycine [INN-French]
Dactinomycinum
Dactinomycinum [INN-Latin]
Dilactone Actinomycin D Acid
Dilactone Actinomycindioic D Acid
Dilactone actin omycindioic D acid
Dilactone actinomycin D acid
Dilactone actinomycindioic D acid
EINECS 200-063-6
FT-0080366
GNF-PF-1977
HBF 386
HBF 386 Meractinomycin
HBF 386 meractinomycin
HMS2052O17
HSDB 3220
LMPK14000005
LS-142
Lyovac Cosmegen
Lyovac cosmegen
MEGxm0_000350
MLS001424196
Meractinomycin
MolPort-001-739-741
MolPort-003-925-177
NCGC00025059-02
NCGC00090796-01
NCGC00161622-01
NCGC00161622-02
NCGC00169767-01
NCI-C04682
NCI60_030539
NP-005932
NSC 3053
NSC-3053
NSC191297
NSC3053
Neuro_000003
Oncostatin K
Oxamide
PXZ-THR-DVA-PRO-SAR-MVA-THR-DVA-PRO-SAR-MVA
SAM001246846
SMP1_000005
SMR000469227
UNII-1CC1JFE158
UPCMLD-DP055
UPCMLD-DP055:001
UPCMLD-DP055:002
WLN: 16- AN FVN IVN LVO PVM SVTJ G1 J1 KY1&1 N1 RY1&1
X 97
actd
actinomycin D
actinomycin cl
actinomycin x i
actinomyein-theo-val-pro-sar-meval
dactinomyein d
o)-(1-oxo-1,2-ethanediyl)]bis(N-methyl)L-valine
3
LenograstimapprovedPhase 21202135968-09-1
Synonyms:
G-CSF (CHO cell derived)
Glycosylated recombinant G-CSF
Glycosylated recombinant granulocyte colony stimulating factor
 
Granulocyte colony stimulating factor 3 (CHO cell derived)
Granulocyte colony-stimulating factor lenograstim
Lenograstim (genetical recombination)
Lenograstim rDNA
4
MechlorethamineapprovedPhase 237751-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
 
KBioGR_001448
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
β,β'-dichlorodiethyl-N-methylamine
5
Vincristineapproved, investigationalPhase 29042068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
6
MesnaapprovedPhase 225819767-45-4, 3375-50-6598
Synonyms:
2-Mercaptoethanesulfonate
2-Mercaptoethanesulfonic acid
 
2-mercaptoethane sulfonate Na
CoM
Coenzyme M
HS-CoM
7
Cyclophosphamideapproved, investigationalPhase 2282950-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Anhydrous cyclophosphamide
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
 
DB00531
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
8
EtoposideapprovedPhase 2123233419-42-036462
Synonyms:
(-)-Etoposide
121471-01-0
136598-18-0
201594-04-9
33419-42-0
35317-32-9
4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside
4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin ethylidene-.beta.-D-glucoside
4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin
4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside
4-Demethylepipodophyllotoxin-.beta.-D-ethylideneglucoside
51854-34-3
76576-58-4
9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-D)-1,3-dioxol-6(5ah)-one
AB00438905
AC1L1FN8
AC1L1VT3
AC1L6246
AC1NR4OG
AC1O4WGG
AC1O7M1N
AC1Q47JJ
Ambap33419-42-0
BPBio1_000673
BRD-K37798499-001-02-5
BSPBio_000611
Bio1_000489
Bio1_000978
Bio1_001467
C01576
CCRIS 2392
CHEBI:4911
CHEBI:588795
CHEMBL44657
CID11758093
CID284997
CID3310
CID36462
CID5284558
CID6419930
CID6610299
CPD000112002
D00125
DB00773
DEMETHY-EPIPODOPHYLLOTOXIN,ETHYLIDENE GLUCOSIDE,
Demethyl Epipodophyllotoxin Ethylidine Glucoside
Demethyl-epiodophyllotoxin ethylidene glucoside
Demethylepipodophyllotoxin-beta-D-ethylideneglucoside
E0675
E1383_SIGMA
EINECS 251-509-1
EPE
EPEG
ETOP
Epipodophyllotoxin
Epipodophyllotoxin VP-16213
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-.beta.-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-.beta.-D-glucopyranoside)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
Eposide
Eposin
 
Eposin, Vepesid, VP-16, Toposar, Etoposide
Etopol
Etopophos
Etopophos (phosphate salt)
Etoposid
Etoposide
Etoposide (JP15/USP/INN)
Etoposide (VP16)
Etoposide [USAN:INN:BAN:JAN]
Etoposido
Etoposido [INN-Spanish]
Etoposidum
Etoposidum [INN-Latin]
Etosid
HMS1569O13
HMS2052N05
HMS2089F14
HSDB 6517
I06-0248
KBioSS_002410
LS-1214
Lastet
MLS000049957
MLS001074951
MLS001424283
MLS002153463
MLS002207239
MLS002222184
MolPort-003-983-431
MolPort-004-905-001
MolPort-004-955-161
NCGC00025056-02
NChemBio.2007.10-comp19
NK 171
NSC 141540
NSC-141540
NSC141540
Prestwick0_000396
Prestwick1_000396
Prestwick2_000396
Prestwick3_000396
Prestwick_211
S1225_Selleck
SAM001246880
SMR000112002
SPBio_002532
ST056353
Toposar
UNII-6PLQ3CP4P3
VP 16
VP 16 (pharmaceutical)
VP 16-213
VP 16213
VP-16
VP-16-213
VePESID (TN)
VePesid
Vepesid
Vepesid J
Vepeside
ZINC03830818
ZINC03938684
Zuyeyidal
etoposide
nchembio.573-comp8
nchembio873-comp2
trans-Etoposide
9Anti-Bacterial AgentsPhase 210884
10Antibiotics, AntitubercularPhase 26972
11Nucleic Acid Synthesis InhibitorsPhase 24855
12Protective AgentsPhase 27190
13Alkylating AgentsPhase 24694
14Topoisomerase InhibitorsPhase 24945
15Anti-Infective AgentsPhase 221402
16Isophosphamide mustardPhase 2391
17Antineoplastic Agents, AlkylatingPhase 24474
18Antineoplastic Agents, PhytogenicPhase 25420
19Adjuvants, ImmunologicPhase 22484
20Etoposide phosphatePhase 21232
21Immunosuppressive AgentsPhase 212770
22Antimitotic AgentsPhase 25498
23Antirheumatic AgentsPhase 210627
24tyrosineNutraceuticalPhase 1659

Interventional clinical trials:

idNameStatusNCT IDPhase
1Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood FibrosarcomaTerminatedNCT00072280Phase 2
2Oral TRK Inhibitor LOXO-101 for Treatment of Advanced Pediatric Solid or Primary Central Nervous System TumorsRecruitingNCT02637687Phase 1
3Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK FusionsRecruitingNCT02650401Phase 1

Search NIH Clinical Center for Congenital Fibrosarcoma

Genetic Tests for Congenital Fibrosarcoma

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Anatomical Context for Congenital Fibrosarcoma

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MalaCards organs/tissues related to Congenital Fibrosarcoma:

36
Tongue, Heart

Publications for Congenital Fibrosarcoma

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Articles related to Congenital Fibrosarcoma:

(show top 50)    (show all 63)
idTitleAuthorsYear
1
Fetal paravertebral congenital fibrosarcoma: MR imaging findings. (26711551)
2016
2
Fetal presentation of congenital fibrosarcoma of the meninges: case report and literature review. (25492889)
2015
3
Characterization of a novel fusion gene EML4-NTRK3 in a case of recurrent congenital fibrosarcoma. (27148571)
2015
4
Congenital fibrosarcoma in complete remission with Somatostatin, Bromocriptine, Retinoids, Vitamin D3, Vitamin E, Vitamin C, Melatonin, Calcium, Chondroitin sulfate associated with low doses of Cyclophosphamide in a 14-year Follow up. (26921571)
2015
5
Congenital fibrosarcoma of the bowel: Sonographic description of a rare case of neonatal intestinal obstruction. (24281989)
2013
6
Congenital fibrosarcoma and history of prenatal exposure to petroleum derivatives. (22945410)
2012
7
Recurrent congenital fibrosarcoma with heart metastases. (22217490)
2012
8
Congenital fibrosarcoma of the ileum: case report with molecular confirmation and literature review. (21355680)
2011
9
A giant congenital fibrosarcoma of the leg. (20442675)
2010
10
Congenital fibrosarcoma of the chest wall: report of a case. (21430833)
2010
11
Congenital fibrosarcoma as cause for fetal anemia: prenatal diagnosis and in utero treatment. (19018145)
2008
12
Congenital fibrosarcoma with a novel complex 3-way translocation t(12;15;19) and unusual histologic features. (18657299)
2008
13
Unilateral mosaic cutaneous vascular lesions, enchondroma, multiple soft tissue chondromas and congenital fibrosarcoma--a variant of Maffucci syndrome? (18429781)
2008
14
Congenital fibrosarcoma simulating congenital hemangioma. (18304187)
2008
15
Congenital fibrosarcoma of the upper extremity--a case report and review of literature. (16366098)
2005
16
Combined prenatal ultrasound and magnetic resonance imaging in an extensive congenital fibrosarcoma: a case report and review of the literature. (15980638)
2005
17
Congenital fibrosarcoma with metastasis in a fetus. (15022058)
2004
18
Management of extensive congenital fibrosarcoma with preoperative chemotherapy. (15456453)
2004
19
Differential diagnosis of congenital fibrosarcoma. (15262440)
2004
20
Congenital fibrosarcoma of the jejunum in a premature infant with meconium peritonitis. (12776248)
2003
21
Chemotherapy alone for the treatment of congenital fibrosarcoma: is surgery always needed? (12555264)
2003
22
Cellular mesoblastic nephroma: morphologic, cytogenetic and molecular links with congenital fibrosarcoma. (12650516)
2003
23
Regression of congenital fibrosarcoma to hemangiomatous remnant with histological and genetic findings. (12406191)
2002
24
The detection of Tel-TrkC chimeric transcripts is more specific than TrkC immunoreactivity for the diagnosis of congenital fibrosarcoma. (11169520)
2001
25
ETV6-NTRK3 gene fusion in metastasizing congenital fibrosarcoma. (10918240)
2000
26
Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia. (10775267)
2000
27
Molecular detection of the ETV6-NTRK3 gene fusion differentiates congenital fibrosarcoma from other childhood spindle cell tumors. (10895816)
2000
28
Prenatal sonographic appearance of congenital fibrosarcoma. (9608374)
1998
29
Congenital fibrosarcoma of the upper extremity. (9734437)
1998
30
A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma. (9462753)
1998
31
ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma. (9823307)
1998
32
Congenital palmar nodule in an infant. Congenital fibrosarcoma. (9192424)
1997
33
Are infantile myofibromatosis, congenital fibrosarcoma and congenital haemangiopericytoma histogenetically related? (7713484)
1995
34
Congenital fibrosarcoma. Report of three cases. (8772821)
1995
35
Congenital fibrosarcoma masquerading as congenital hemangioma: report of two cases. (8523253)
1995
36
Intrathoracic congenital fibrosarcoma. A case report. (7608883)
1995
37
Congenital fibrosarcoma masquerading as lymphatic malformation: report of two cases. (7722837)
1995
38
Pediatric case of the day. Congenital fibrosarcoma (CFS). (7899610)
1995
39
Trisomy 11 and other nonrandom trisomies in congenital fibrosarcoma. (7987812)
1994
40
Consistent numerical chromosome aberrations in congenital fibrosarcoma. (8453601)
1993
41
Limb congenital fibrosarcoma: report of two cases and review of the literature. (8292522)
1993
42
Ultrastructural, immunocytochemical, and cytogenetic characterization of a large congenital fibrosarcoma. (1524466)
1992
43
Cytogenetic analysis of a congenital fibrosarcoma. (2009510)
1991
44
Deletion of part of the short arm of chromosome 17 in a congenital fibrosarcoma. (2204476)
1990
45
Cytogenetic investigation of a case of congenital fibrosarcoma. (2731143)
1989
46
Congenital fibrosarcoma. (3612464)
1987
47
Congenital fibrosarcoma of the forearm. A case report. (3957990)
1986
48
Congenital fibrosarcoma: a congenital fibrous histiocytoma. (3035524)
1986
49
Complete response of congenital fibrosarcoma to chemotherapy. (2878294)
1986
50
Congenital fibrosarcoma. Preoperative chemotherapy and conservative surgery. (3755646)
1986

Variations for Congenital Fibrosarcoma

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Expression for genes affiliated with Congenital Fibrosarcoma

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Search GEO for disease gene expression data for Congenital Fibrosarcoma.

Pathways for genes affiliated with Congenital Fibrosarcoma

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Pathways related to Congenital Fibrosarcoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Neurotrophic factor-mediated Trk receptor signaling42
Show member pathways
9.5NTF3, NTRK3
2
Aurora B signaling42
Show member pathways
9.3DES, VIM
3
Neural Stem Cell Differentiation Pathways and Lineage-specific Markers59
9.3NTF3, VIM
4
Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases65
Show member pathways
9.1ACTC1, NTF3, NTRK3
5
Cytoskeletal Signaling3
8.9ACTC1, DES, VIM
6
Striated Muscle Contraction42 60
8.9ACTC1, DES, VIM

GO Terms for genes affiliated with Congenital Fibrosarcoma

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Cellular components related to Congenital Fibrosarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.3DES, VIM

Biological processes related to Congenital Fibrosarcoma according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1activation of GTPase activityGO:009063010.2NTF3, NTRK3
2activation of protein kinase B activityGO:003214810.2NTF3, NTRK3
3positive regulation of actin cytoskeleton reorganizationGO:200025110.2NTF3, NTRK3
4intermediate filament organizationGO:004510910.0DES, VIM
5positive regulation of peptidyl-serine phosphorylationGO:00331389.5NTF3, NTRK3
6muscle filament slidingGO:00300499.5ACTC1, DES, VIM
7positive regulation of gene expressionGO:00106289.5ACTC1, NTRK3, VIM

Sources for Congenital Fibrosarcoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z