Congenital Fibrosarcoma disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Summaries for Congenital Fibrosarcoma

MalaCards based summary: Congenital Fibrosarcoma, also known as infantile fibrosarcoma, is related to fibrosarcoma and congenital mesoblastic nephroma. An important gene associated with Congenital Fibrosarcoma is NTRK3 (neurotrophic tyrosine kinase, receptor, type 3). The compounds vegf and imatinib have been mentioned in the context of this disorder. Affiliated tissues include tongue and heart.

Aliases & Classifications for Congenital Fibrosarcoma

Sources:
⁹Disease Ontology, ¹¹DISEASES, ⁶¹UMLS, ⁵⁶SNOMED-CT, ³⁹NCIt
See all sources

Congenital Fibrosarcoma, Aliases & Descriptions:

Name: Congenital Fibrosarcoma ⁹ ¹¹ ⁶¹

Infantile Fibrosarcoma ⁹ ⁶¹

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Bone diseases

External Ids:

Disease Ontology⁹ DOID:8418

SNOMED-CT⁵⁶ 403996004, 52040006

NCIt³⁹ C4244

UMLS⁶¹ C0334459

Related Diseases for Congenital Fibrosarcoma

Sources:
¹⁸GeneCards, ¹⁹GeneDecks
See all sources

Diseases in the Fibrosarcoma family:

congenital fibrosarcoma	Adult Fibrosarcoma

Diseases related to Congenital Fibrosarcoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 32)

id	Related Disease	Score	Top Affiliating Genes
1	fibrosarcoma	31.5	NTRK3, ETV6
2	congenital mesoblastic nephroma	30.5	ETV6, NTRK3
3	hemangioma	10.2
4	mesoblastic nephroma	10.2
5	sacrococcygeal teratoma	10.1
6	wilms tumor	10.1
7	fibroma	10.1
8	spindle cell lipoma	10.1
9	myofibroma	10.1
10	urticaria pigmentosa	10.1
11	cellular congenital mesoblastic nephroma	10.1
12	fasciitis	10.1
13	lipoma	10.1
14	rhabdomyosarcoma	10.1
15	sarcoma	10.1
16	urticaria	10.1
17	teratoma	10.1
18	calcified aponeurotic fibroma	10.1
19	bone marrow cancer	10.0	NTRK3, ETV6
20	leukemia	10.0
21	fibrous histiocytoma	10.0
22	choroiditis	10.0
23	chondroma	10.0
24	histiocytoma	10.0
25	intestinal obstruction	10.0
26	peritonitis	10.0
27	enchondroma	10.0
28	infantile myofibromatosis	10.0
29	chronic myeloid leukemia	10.0	NTRK3, ETV6
30	breast cancer	10.0	NTRK3, ETV6
31	acute leukemia	10.0	NTRK3, ETV6
32	myeloid leukemia	9.9	NTRK3, ETV6

Graphical network of the top 20 diseases related to Congenital Fibrosarcoma:

Symptoms for Congenital Fibrosarcoma

Drugs & Therapeutics for Congenital Fibrosarcoma

Sources:
⁴¹NIH Clinical Center, ⁶ClinicalTrials
See all sources

Drug clinical trials:

Search ClinicalTrials for Congenital Fibrosarcoma

Search NIH Clinical Center for Congenital Fibrosarcoma

Genetic Tests for Congenital Fibrosarcoma

Anatomical Context for Congenital Fibrosarcoma

Sources:
³²MalaCards
See all sources

MalaCards organs/tissues related to Congenital Fibrosarcoma:

³²

Tongue, Heart

Animal Models for Congenital Fibrosarcoma or affiliated genes

Publications for Congenital Fibrosarcoma

Sources:
⁵¹PubMed
See all sources

Articles related to Congenital Fibrosarcoma:

(show top 50) (show all 58)

id	Title	Authors	Year
1	Congenital fibrosarcoma of the bowel: Sonographic description of a rare case of neonatal intestinal obstruction. (24281989)	Bruno C.... Pozzi-Mucelli R.	2013
2	Congenital fibrosarcoma and history of prenatal exposure to petroleum derivatives. (22945410)	Ortega-GarcA-a J.A.... FerrA-s-Tortajada J.	2012
3	Congenital fibrosarcoma of the ileum: case report with molecular confirmation and literature review. (21355680)	Rizkalla H.... O'Sullivan M.J.	2011
4	A giant congenital fibrosarcoma of the leg. (20442675)	ErtA1rk C.... OzsaraAs M.C.	2010
5	Congenital fibrosarcoma of the chest wall: report of a case. (21430833)	Gupta S.S.... Mathur R.K.	2010
6	Congenital fibrosarcoma with a novel complex 3-way translocation t(12;15;19) and unusual histologic features. (18657299)	MariA+o-EnrA-quez A.... Reyes-MA_gica M.	2008
7	Unilateral mosaic cutaneous vascular lesions, enchondroma, multiple soft tissue chondromas and congenital fibrosarcoma--a variant of Maffucci syndrome? (18429781)	Katz P.... Drolet B.	2008
8	Congenital fibrosarcoma as cause for fetal anemia: prenatal diagnosis and in utero treatment. (19018145)	Scheier M.... Marth C.	2008
9	Congenital fibrosarcoma simulating congenital hemangioma. (18304187)	Requena C.... GuillAcn C.	2008
10	Congenital fibrosarcoma of the upper extremity--a case report and review of literature. (16366098)	Sachdev R.... Mandal A.K.	2005
11	Combined prenatal ultrasound and magnetic resonance imaging in an extensive congenital fibrosarcoma: a case report and review of the literature. (15980638)	Huang S.Y.... Chao A.S.	2005
12	Congenital fibrosarcoma with metastasis in a fetus. (15022058)	Nonaka D.... Sun C.C.	2004
13	Management of extensive congenital fibrosarcoma with preoperative chemotherapy. (15456453)	Grohn M.L.... Suppiah R.	2004
14	Congenital fibrosarcoma of the jejunum in a premature infant with meconium peritonitis. (12776248)	Shima Y.... Hashizume K.	2003
15	Chemotherapy alone for the treatment of congenital fibrosarcoma: is surgery always needed? (12555264)	Surico G.... Minervini C.	2003
16	Cellular mesoblastic nephroma: morphologic, cytogenetic and molecular links with congenital fibrosarcoma. (12650516)	Henno S.... Dubus P.	2003
17	Regression of congenital fibrosarcoma to hemangiomatous remnant with histological and genetic findings. (12406191)	Miura K.... Tsutsui Y.	2002
18	The detection of Tel-TrkC chimeric transcripts is more specific than TrkC immunoreactivity for the diagnosis of congenital fibrosarcoma. (11169520)	Dubus P.... Merlio J.P.	2001
19	Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia. (10775267)	Liu Q.... Gilliland D.G.	2000
20	Molecular detection of the ETV6-NTRK3 gene fusion differentiates congenital fibrosarcoma from other childhood spindle cell tumors. (10895816)	Bourgeois J.M.... Sorensen P.H.	2000
21	Prenatal sonographic appearance of congenital fibrosarcoma. (9608374)	Tadmor O.P.... Diamant Y.Z.	1998
22	Congenital fibrosarcoma of the upper extremity. (9734437)	Pousti T.J.... Grier H.	1998
23	A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma. (9462753)	Knezevich S.R.... Sorensen P.H.	1998
24	Congenital palmar nodule in an infant. Congenital fibrosarcoma. (9192424)	Tay Y.K.... Weston W.L.	1997
25	Intrathoracic congenital fibrosarcoma. A case report. (7608883)	Dolkart L.A.... Kuonen C.A.	1995
26	Congenital fibrosarcoma masquerading as lymphatic malformation: report of two cases. (7722837)	Hayward P.G.... Perez-Atayde A.R.	1995
27	Are infantile myofibromatosis, congenital fibrosarcoma and congenital haemangiopericytoma histogenetically related? (7713484)	Variend S.... van Gorp J.	1995
28	Congenital fibrosarcoma. Report of three cases. (8772821)	Singh V.P.... Lakhtakia R.	1995
29	Pediatric case of the day. Congenital fibrosarcoma (CFS). (7899610)	Fink A.M.... Magee J.F.	1995
30	Limb congenital fibrosarcoma: report of two cases and review of the literature. (8292522)	Ben Arush M.W.... Meller I.	1993
31	Consistent numerical chromosome aberrations in congenital fibrosarcoma. (8453601)	Sankary S.... Gollin S.M.	1993
32	Ultrastructural, immunocytochemical, and cytogenetic characterization of a large congenital fibrosarcoma. (1524466)	Argyle J.C.... Schneider N.R.	1992
33	Deletion of part of the short arm of chromosome 17 in a congenital fibrosarcoma. (2204476)	Gorman P.A.... Sheer D.	1990
34	Cytogenetic investigation of a case of congenital fibrosarcoma. (2731143)	Speleman F.... van den Berghe H.	1989
35	Congenital fibrosarcoma. (3612464)	Blocker S.... Ternberg J.	1987
36	Congenital fibrosarcoma of the forearm. A case report. (3957990)	Martell J.R.... Barja R.H.	1986
37	Congenital fibrosarcoma: a congenital fibrous histiocytoma. (3035524)	Drut R.	1986
38	Complete response of congenital fibrosarcoma to chemotherapy. (2878294)	Delepine N.... Voisin M.C.	1986
39	Congenital fibrosarcoma. Preoperative chemotherapy and conservative surgery. (3755646)	Ninane J.... Cornu G.	1986
40	Congenital fibrosarcoma of the tongue. A case report. (6674897)	Iannucci A.M.... Menestrina F.	1983
41	Congenital fibrosarcoma of the axilla in an infant. (6675544)	Chiba T.	1983
42	Congenital fibrosarcoma of the tongue. (7064583)	Zanetti B.... Ottolenghi A.	1982
43	Case report 149. Infantile congenital fibrosarcoma of humerus. (7268465)	FaurAc C.... Boccon-Gibod L.	1981
44	Congenital fibrosarcoma: presence of a histiocytic component. (7388769)	Gonzalez-Crussi F.... Sotelo-Avila C.	1980
45	Congenital fibrosarcoma metastatic to the choroid. (443333)	Rootman J.... Dimmick J.E.	1979
46	Pancreaticoduodenectomy in the treatment of congenital fibrosarcoma of the duodenum. (1185470)	Shearburn E.W.... Shaw A.	1975
47	Congenital fibrosarcoma of the thoracolumbar region. (4607996)	Grubb R.L.... Dehner L.P.	1974
48	Ultrastructure of congenital fibrosarcoma. (5483658)	Gonzalez-Crussi F.	1970
49	Congenital fibrosarcoma. (13095275)	HARTZ P.H.... GUERRERO TABLANTE T.	1953
50	Congenital fibrosarcoma; report of a case in a newborn infant. (14818531)	WILLIAMS J.O.... SCHRUM D.	1951

Genes related to Congenital Fibrosarcoma

Sources:
¹⁸GeneCards, ¹antibodies-online, ⁴⁵Novus Biologicals
See all sources

Genes related to Congenital Fibrosarcoma:

- Elite gene

id	Symbol	Description	Score	Implication
1	NTRK3	neurotrophic tyrosine kinase, receptor, type 3	22.35	GeneCards inferred via : Publications, Functions (show sections)
2	ETV6	ets variant 6	17.92	GeneCards inferred via : Publications, Disorders, Functions, Summaries (show sections)
3	GOLGA6A	golgin A6 family, member A	12.35	GeneCards inferred via : Disorders (show sections)
4	GOLGA6B	golgin A6 family, member B	7.35	GeneCards inferred via : Disorders (show sections)