MCID: CNG022
MIFTS: 22

Congenital Granular Cell Tumor malady

Cancer category

Summaries for Congenital Granular Cell Tumor

Sources:
33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Congenital Granular Cell Tumor is related to granular cell tumor and congenital epulis. An important gene associated with Congenital Granular Cell Tumor is S100B (S100 calcium binding protein B). The compounds glutamine and heparin have been mentioned in the context of this disorder. Affiliated tissues include tongue.

Aliases & Classifications for Congenital Granular Cell Tumor

Sources:
8Disease Ontology, 61UMLS
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer


Aliases & Descriptions:

congenital granular cell tumor 8


External Ids:

Disease Ontology8 DOID:8303

Related Diseases for Congenital Granular Cell Tumor

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the granular cell tumor family:

congenital granular cell tumor

Diseases related to Congenital Granular Cell Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 70)
idRelated DiseaseScoreTop Affiliating Genes
1granular cell tumor31.1ENO2, CD68, S100B, VIM
2congenital epulis10.5
3osteoarthritis10.0CD68
4cutaneous fibrous histiocytoma10.0CD68
5hemangioma10.0CD68
6angiomyolipoma10.0VIM
7rhabdoid tumor10.0VIM
8angiosarcoma10.0VIM
9encephalitis10.0CD68
10syringoma10.0S100B
11glomus tumor10.0VIM
12hepatitis10.0SERPINA1
13epulis10.0ENO2
14subependymal giant cell astrocytoma10.0ENO2
15schizophrenia10.0S100B
16merkel cell carcinoma10.0ENO2
17cerebral primitive neuroectodermal tumor10.0ENO2
18rhabdoid cancer10.0ENO2
19anaplastic large cell lymphoma10.0ENO2
20neurilemmoma10.0ENO2
21peripheral primitive neuroectodermal tumor10.0ENO2
22adenoma10.0ENO2
23histiocytosis10.0S100B, CD68
24colorectal cancer10.0SERPINA1
25letterer-siwe disease10.0S100B, CD68
26dermatofibrosarcoma protuberans10.0S100B, VIM
27spindle cell sarcoma10.0VIM, S100B
28astrocytoma10.0S100B, VIM
29fibrous histiocytoma10.0VIM, S100B
30malignant glioma10.0ENO2
31psoriasis10.0SERPINA1
32sex cord-gonadal stromal tumor10.0S100B, VIM
33perineurioma10.0VIM, S100B
34myoepithelioma10.0VIM, S100B
35malignant peripheral nerve sheath tumor10.0VIM, S100B
36giant cell tumor10.0VIM, S100B
37pleomorphic adenoma10.0S100B, VIM
38adenoid cystic carcinoma10.0S100B, VIM
39synovial sarcoma10.0S100B, VIM
40hemangiopericytoma10.0S100B, VIM
41smooth muscle tumor10.0VIM, S100B
42rheumatoid arthritis10.0SERPINA1, CD68
43hemangioblastoma10.0S100B, ENO2
44paraganglioma10.0ENO2, S100B
45olfactory neuroblastoma10.0ENO2, S100B
46alveolar soft part sarcoma10.0VIM, ENO2
47neurofibroma10.0S100B, VIM
48pineocytoma10.0S100B, ENO2
49retinoblastoma10.0ENO2
50stomach cancer10.0SERPINA1

Graphical network of the top 20 diseases related to Congenital Granular Cell Tumor:



Diseases related to congenital granular cell tumor

Clinical Features for Congenital Granular Cell Tumor

Drugs & Therapeutics for Congenital Granular Cell Tumor

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Congenital Granular Cell Tumor

Drug clinical trials:

Search ClinicalTrials for Congenital Granular Cell Tumor

Search NIH Clinical Center for Congenital Granular Cell Tumor

Search CenterWatch for Congenital Granular Cell Tumor

Genetic Tests for Congenital Granular Cell Tumor

Anatomical Context for Congenital Granular Cell Tumor

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Congenital Granular Cell Tumor:

33
Tongue

Animal Models for Congenital Granular Cell Tumor or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Congenital Granular Cell Tumor

Sources:
51PubMed
See all sources

Articles related to Congenital Granular Cell Tumor:

(show all 28)
idTitleAuthorsYear
1
Congenital granular cell tumor with uncommon clinical behavior. (23917999)
2013
2
Solitary S-100-Positive Congenital Granular Cell Tumor of the Tongue: A Case Report and Literature Review. (23241807)
2012
3
Congenital granular cell tumor of the alveolar ridge. (20551547)
2010
4
Congenital granular cell epulis presents an immunohistochemical profile that distinguishes it from the granular cell tumor of the adult. (19205730)
2009
5
Congenital granular cell tumor. (19461349)
2009
6
A newborn baby with a tumor protruding from the mouth. Diagnosis: congenital gingival granular cell tumor. (17994174)
2007
7
Congenital granular cell tumor (congenital epulis): a lesion of multidisciplinary interest. (17909507)
2007
8
Prenatal diagnosis and multidisciplinary approach to the congenital gingival granular cell tumor. (17011257)
2006
9
Pathology quiz case. Gingival granular cell tumor of the newborn (GGCTN) (congenital epulis). (16847196)
2006
10
Congenital granular cell tumor (epulis): postnatal imaging appearances. (16012311)
2005
11
Pathologic quiz case: a newborn with a midline buccal mucosa mass. Congenital gingival granular cell tumor (congenital epulis). (15086295)
2004
12
Obstructive congenital gingival granular cell tumor. (12731638)
2003
13
Congenital granular-cell tumor of the gingiva. (9799384)
1998
14
Congenital gingival granular cell tumor--a case report. (10635140)
1998
15
Congenital granular cell tumor in the newborn. (9627266)
1998
16
Congenital granular cell tumor (congenital epulis) in the fetus: a case report. (9371136)
1997
17
Immunoreactivity of S100 protein, alpha-1-antitrypsin, and CD68 in adult and congenital granular cell tumors. (8878020)
1996
18
Congenital epulis and granular cell tumor: a histologic and immunohistochemical study. (8680977)
1995
19
In utero diagnosis of a congenital gingival granular cell tumor and immediate postnatal surgical management. (8169714)
1994
20
Congenital gingival granular cell tumor of newborn. (7883337)
1994
21
Congenital gingival granular cell tumor. A case report. (7692016)
1993
22
Congenital granular cell tumor with systemic involvement. Immunohistochemical and ultrastructural study. (1929790)
1991
23
Immunohistochemical study of congenital gingival granular cell tumor (congenital epulis). (1962817)
1990
24
Congenital granular cell tumor of the tongue. (3667301)
1987
25
Gingival granular cell tumor of the newborn (congenital "epulis"): ultrastructural observations relating to histogenesis. (6282735)
1982
26
Congenital epulis (gingival granular cell tumor): ultrastructural evidence of origin from pericytes. (6948253)
1982
27
Congenital granular-cell tumor of alveolar ridge and tongue. Report of two cases. (168531)
1975
28
Ultrastructural observations on a gingival granular cell tumor (congenital epulis). (4323614)
1971

Genetic Variations for Congenital Granular Cell Tumor

Expression for genes affiliated with Congenital Granular Cell Tumor

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Congenital Granular Cell Tumor

Search GEO for disease gene expression data for Congenital Granular Cell Tumor.

Pathways for genes affiliated with Congenital Granular Cell Tumor

Compounds for genes affiliated with Congenital Granular Cell Tumor

Sources:
45Novoseek, 29IUPHAR, 11DrugBank, 24HMDB, 50PharmGKB, 60Tocris Bioscience, 2BitterDB
See all sources

Compounds related to Congenital Granular Cell Tumor according to GeneCards/GeneDecks:

(show all 40)
idCompoundScoreTop Affiliating Genes
1glutamine4510.2ENO2
2heparin45 29 11 2412.9S100B, SERPINA1
3edss459.9ENO2, S100B
4l-amino acid459.8S100B, ENO2
5orcein459.8VIM, S100B
6eosin459.8S100B, VIM
7reticulin459.7S100B, VIM
8mucicarmine459.7S100B, VIM
9toluidine459.7VIM, ENO2
10b 723459.7S100B, VIM
11alpha-naphthyl acetate459.5CD68, ENO2
12hydroxyapatite459.5S100B, VIM
134-hydroxytamoxifen459.4S100B, VIM
14acth459.3ENO2, SERPINA1, S100B
15s 100459.3VIM, S100B, ENO2
16hematoxylin459.3ENO2, S100B, VIM
17dbc-amp459.3VIM, S100B, ENO2
18catecholamine459.3ENO2, S100B, VIM
19bromodeoxyuridine459.2ENO2, S100B, VIM
20choline45 11 2411.2ENO2, S100B, VIM
21formaldehyde45 2410.2VIM, S100B, ENO2
22ganglioside459.2VIM, ENO2
23gaba459.2VIM, S100B, ENO2
24etoposide45 50 60 1112.2VIM, S100B, ENO2
25methionine459.2SERPINA1, S100B, VIM
26thymidine45 2410.2S100B, SERPINA1, ENO2
27acetylcholine45 50 29 11 2413.2VIM, S100B, ENO2
28forskolin45 50 1111.1VIM, S100B, ENO2
29colchicine60 45 2 29 1113.1S100B, VIM
30lactate459.1ENO2, S100B, VIM
31aspartate459.1ENO2, S100B, VIM
32leucine459.0ENO2, S100B, VIM
33adenylate459.0VIM, S100B, ENO2
34testosterone45 60 11 2411.9ENO2, S100B, VIM
35iron45 249.8ENO2, SERPINA1, S100B, VIM
36creatinine458.8ENO2, SERPINA1, S100B, VIM
37progesterone45 60 29 11 2412.7ENO2, SERPINA1, S100B, VIM
38estrogen458.7ENO2, SERPINA1, S100B, VIM
39paraffin458.0ENO2, SERPINA1, CD68, S100B, VIM
40lipid457.9VIM, S100B, CD68, SERPINA1, ENO2

GO Terms for genes affiliated with Congenital Granular Cell Tumor

Sources:
16Gene Ontology
See all sources

Molecular functions related to Congenital Granular Cell Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:0428028.9SERPINA1, S100B, VIM

Products for genes affiliated with Congenital Granular Cell Tumor

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Congenital Granular Cell Tumor

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet