MCID: CNG022
MIFTS: 29

Congenital Granular Cell Tumor malady

Cancer diseases category

Summaries for Congenital Granular Cell Tumor

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32MalaCards
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MalaCards: Congenital Granular Cell Tumor is related to granular cell tumor and epulis. An important gene associated with Congenital Granular Cell Tumor is S100B (S100 calcium binding protein B). The compounds glutamine and heparin have been mentioned in the context of this disorder. Affiliated tissues include tongue.

Aliases & Classifications for Congenital Granular Cell Tumor

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8Disease Ontology, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

congenital granular cell tumor 8


External Ids:

Disease Ontology8 DOID:8303

Related Diseases for Congenital Granular Cell Tumor

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17GeneCards, 18GeneDecks
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Diseases in the Granular Cell Tumor family:

congenital granular cell tumor

Diseases related to Congenital Granular Cell Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 70)
idRelated DiseaseScoreTop Affiliating Genes
1granular cell tumor31.0ENO2, CD68, S100B, VIM
2epulis30.6ENO2
3congenital epulis10.5
4osteoarthritis10.0CD68
5cutaneous fibrous histiocytoma10.0CD68
6hemangioma10.0CD68
7angiomyolipoma10.0VIM
8rhabdoid tumor10.0VIM
9angiosarcoma10.0VIM
10encephalitis10.0CD68
11syringoma10.0S100B
12glomus tumor10.0VIM
13hepatitis10.0SERPINA1
14subependymal giant cell astrocytoma10.0ENO2
15schizophrenia10.0S100B
16merkel cell carcinoma10.0ENO2
17cerebral primitive neuroectodermal tumor10.0ENO2
18rhabdoid cancer10.0ENO2
19anaplastic large cell lymphoma10.0ENO2
20neurilemmoma10.0ENO2
21peripheral primitive neuroectodermal tumor10.0ENO2
22adenoma10.0ENO2
23histiocytosis10.0S100B, CD68
24colorectal cancer10.0SERPINA1
25letterer-siwe disease10.0S100B, CD68
26dermatofibrosarcoma protuberans10.0S100B, VIM
27spindle cell sarcoma10.0VIM, S100B
28astrocytoma10.0S100B, VIM
29fibrous histiocytoma10.0VIM, S100B
30malignant glioma10.0ENO2
31psoriasis10.0SERPINA1
32sex cord-gonadal stromal tumor10.0S100B, VIM
33perineurioma10.0VIM, S100B
34myoepithelioma10.0VIM, S100B
35malignant peripheral nerve sheath tumor10.0VIM, S100B
36giant cell tumor10.0VIM, S100B
37pleomorphic adenoma10.0S100B, VIM
38adenoid cystic carcinoma10.0S100B, VIM
39synovial sarcoma10.0S100B, VIM
40hemangiopericytoma10.0S100B, VIM
41smooth muscle tumor10.0VIM, S100B
42rheumatoid arthritis10.0SERPINA1, CD68
43hemangioblastoma10.0S100B, ENO2
44paraganglioma10.0ENO2, S100B
45olfactory neuroblastoma10.0ENO2, S100B
46alveolar soft part sarcoma10.0VIM, ENO2
47neurofibroma10.0S100B, VIM
48pineocytoma10.0S100B, ENO2
49retinoblastoma10.0ENO2
50stomach cancer10.0SERPINA1

Graphical network of the top 20 diseases related to Congenital Granular Cell Tumor:



Diseases related to congenital granular cell tumor

Clinical Features for Congenital Granular Cell Tumor

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Drugs & Therapeutics for Congenital Granular Cell Tumor

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Congenital Granular Cell Tumor

Drug clinical trials:

Search ClinicalTrials for Congenital Granular Cell Tumor

Search NIH Clinical Center for Congenital Granular Cell Tumor

Search CenterWatch for Congenital Granular Cell Tumor

Genetic Tests for Congenital Granular Cell Tumor

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Anatomical Context for Congenital Granular Cell Tumor

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32MalaCards
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MalaCards organs/tissues related to Congenital Granular Cell Tumor:

32
Tongue

Animal Models for Congenital Granular Cell Tumor or affiliated genes

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Publications for Congenital Granular Cell Tumor

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50PubMed
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Articles related to Congenital Granular Cell Tumor:

(show all 28)
idTitleAuthorsYear
1
Congenital granular cell tumor with uncommon clinical behavior. (23917999)
2013
2
Solitary S-100-Positive Congenital Granular Cell Tumor of the Tongue: A Case Report and Literature Review. (23241807)
2012
3
Congenital granular cell tumor of the alveolar ridge. (20551547)
2010
4
Congenital granular cell epulis presents an immunohistochemical profile that distinguishes it from the granular cell tumor of the adult. (19205730)
2009
5
Congenital granular cell tumor. (19461349)
2009
6
A newborn baby with a tumor protruding from the mouth. Diagnosis: congenital gingival granular cell tumor. (17994174)
2007
7
Congenital granular cell tumor (congenital epulis): a lesion of multidisciplinary interest. (17909507)
2007
8
Prenatal diagnosis and multidisciplinary approach to the congenital gingival granular cell tumor. (17011257)
2006
9
Pathology quiz case. Gingival granular cell tumor of the newborn (GGCTN) (congenital epulis). (16847196)
2006
10
Congenital granular cell tumor (epulis): postnatal imaging appearances. (16012311)
2005
11
Pathologic quiz case: a newborn with a midline buccal mucosa mass. Congenital gingival granular cell tumor (congenital epulis). (15086295)
2004
12
Obstructive congenital gingival granular cell tumor. (12731638)
2003
13
Congenital granular-cell tumor of the gingiva. (9799384)
1998
14
Congenital gingival granular cell tumor--a case report. (10635140)
1998
15
Congenital granular cell tumor in the newborn. (9627266)
1998
16
Congenital granular cell tumor (congenital epulis) in the fetus: a case report. (9371136)
1997
17
Immunoreactivity of S100 protein, alpha-1-antitrypsin, and CD68 in adult and congenital granular cell tumors. (8878020)
1996
18
Congenital epulis and granular cell tumor: a histologic and immunohistochemical study. (8680977)
1995
19
In utero diagnosis of a congenital gingival granular cell tumor and immediate postnatal surgical management. (8169714)
1994
20
Congenital gingival granular cell tumor of newborn. (7883337)
1994
21
Congenital gingival granular cell tumor. A case report. (7692016)
1993
22
Congenital granular cell tumor with systemic involvement. Immunohistochemical and ultrastructural study. (1929790)
1991
23
Immunohistochemical study of congenital gingival granular cell tumor (congenital epulis). (1962817)
1990
24
Congenital granular cell tumor of the tongue. (3667301)
1987
25
Gingival granular cell tumor of the newborn (congenital "epulis"): ultrastructural observations relating to histogenesis. (6282735)
1982
26
Congenital epulis (gingival granular cell tumor): ultrastructural evidence of origin from pericytes. (6948253)
1982
27
Congenital granular-cell tumor of alveolar ridge and tongue. Report of two cases. (168531)
1975
28
Ultrastructural observations on a gingival granular cell tumor (congenital epulis). (4323614)
1971

Genetic Variations for Congenital Granular Cell Tumor

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Expression for genes affiliated with Congenital Granular Cell Tumor

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Congenital Granular Cell Tumor

Search GEO for disease gene expression data for Congenital Granular Cell Tumor.

Pathways for genes affiliated with Congenital Granular Cell Tumor

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Compounds for genes affiliated with Congenital Granular Cell Tumor

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Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 24HMDB, 49PharmGKB, 59Tocris Bioscience, 2BitterDB
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Compounds related to Congenital Granular Cell Tumor according to GeneCards/GeneDecks:

(show all 40)
idCompoundScoreTop Affiliating Genes
1glutamine4410.2ENO2
2heparin44 28 11 2412.9S100B, SERPINA1
3edss449.9ENO2, S100B
4l-amino acid449.8S100B, ENO2
5orcein449.8VIM, S100B
6eosin449.8S100B, VIM
7reticulin449.7S100B, VIM
8mucicarmine449.7S100B, VIM
9toluidine449.7VIM, ENO2
10b 723449.7S100B, VIM
11alpha-naphthyl acetate449.5CD68, ENO2
12hydroxyapatite449.5S100B, VIM
134-hydroxytamoxifen449.4S100B, VIM
14acth449.3ENO2, SERPINA1, S100B
15s 100449.3VIM, S100B, ENO2
16hematoxylin449.3ENO2, S100B, VIM
17dbc-amp449.3VIM, S100B, ENO2
18catecholamine449.3ENO2, S100B, VIM
19bromodeoxyuridine449.2ENO2, S100B, VIM
20choline44 11 2411.2ENO2, S100B, VIM
21formaldehyde44 2410.2VIM, S100B, ENO2
22ganglioside449.2VIM, ENO2
23gaba449.2VIM, S100B, ENO2
24etoposide44 49 59 1112.2VIM, S100B, ENO2
25methionine449.2SERPINA1, S100B, VIM
26thymidine44 2410.2S100B, SERPINA1, ENO2
27acetylcholine44 49 28 11 2413.2VIM, S100B, ENO2
28forskolin44 49 1111.1VIM, S100B, ENO2
29colchicine59 44 2 28 1113.1S100B, VIM
30lactate449.1ENO2, S100B, VIM
31aspartate449.1ENO2, S100B, VIM
32leucine449.0ENO2, S100B, VIM
33adenylate449.0VIM, S100B, ENO2
34testosterone44 59 11 2411.9ENO2, S100B, VIM
35iron44 249.8ENO2, SERPINA1, S100B, VIM
36creatinine448.8ENO2, SERPINA1, S100B, VIM
37progesterone44 59 28 11 2412.7ENO2, SERPINA1, S100B, VIM
38estrogen448.7ENO2, SERPINA1, S100B, VIM
39paraffin448.0ENO2, SERPINA1, CD68, S100B, VIM
40lipid447.9VIM, S100B, CD68, SERPINA1, ENO2

GO Terms for genes affiliated with Congenital Granular Cell Tumor

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16Gene Ontology
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Molecular functions related to Congenital Granular Cell Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:0428028.9SERPINA1, S100B, VIM

Products for genes affiliated with Congenital Granular Cell Tumor

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Congenital Granular Cell Tumor

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet