MCID: CNG171
MIFTS: 14

Congenital Plasminogen Deficiency malady

Summaries for Congenital Plasminogen Deficiency

Sources:
21Genetics Home Reference, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Genetics Home Reference:21 Congenital plasminogen deficiency is a disorder that results in inflamed growths on the mucous membranes, which are the moist tissues that line body openings such as the eyelids and the inside of the mouth. Development of the growths are usually triggered by infections or injury, but they may also occur spontaneously in the absence of known triggers. The growths may recur after being removed.

MalaCards: Congenital Plasminogen Deficiency, also known as hypoplasminogenemia, is related to conjunctivitis ligneous and plasminogen deficiency, types i and ii. An important gene associated with Congenital Plasminogen Deficiency is PLG (plasminogen).

Aliases & Classifications for Congenital Plasminogen Deficiency

Sources:
21Genetics Home Reference, 61UMLS
See all sources

Aliases & Descriptions:

congenital plasminogen deficiency 21
hypoplasminogenemia 21 61
plasminogen deficiency, type i 21


Related Diseases for Congenital Plasminogen Deficiency

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Congenital Plasminogen Deficiency via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1conjunctivitis ligneous10.4
2plasminogen deficiency, types i and ii10.3
3type 1 plasminogen deficiency10.2
4primary pulmonary hypertension10.1
5coats disease10.1
6thromboembolism10.1
7venous thromboembolism10.1

Graphical network of diseases related to Congenital Plasminogen Deficiency:



Diseases related to congenital plasminogen deficiency

Clinical Features for Congenital Plasminogen Deficiency

Drugs & Therapeutics for Congenital Plasminogen Deficiency

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Congenital Plasminogen Deficiency

Drug clinical trials:

Search ClinicalTrials for Congenital Plasminogen Deficiency

Search NIH Clinical Center for Congenital Plasminogen Deficiency

Search CenterWatch for Congenital Plasminogen Deficiency

Genetic Tests for Congenital Plasminogen Deficiency

Anatomical Context for Congenital Plasminogen Deficiency

Animal Models for Congenital Plasminogen Deficiency or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Congenital Plasminogen Deficiency

Sources:
51PubMed
See all sources

Articles related to Congenital Plasminogen Deficiency:

(show all 15)
idTitleAuthorsYear
1
Laryngeal obstruction in congenital plasminogen deficiency. (22328462)
2012
2
The first two Japanese cases of severe type I congenital plasminogen deficiency with ligneous conjunctivitis: successful treatment with direct thrombin inhibitor and fresh plasma. (19373890)
2009
3
Ligneous conjunctivitis secondary to a congenital plasminogen deficiency in a dog. (18312178)
2008
4
Haemostatic management of intraoral bleeding in patients with congenital deficiency of alpha2-plasmin inhibitor or plasminogen activator inhibitor-1. (15357795)
2004
5
Report of a case of congenital plasminogen activator inhibitor-1 deficiency]. (15182577)
2004
6
Anesthetic management of a patient with congenital plasminogen activator inhibitor-1 deficiency]. (12632627)
2003
7
Successful arthroscopic treatment of pigmented villonodular synovitis of the knee in a patient with congenital deficiency of plasminogen activator inhibitor-1 and recurrent haemarthrosis. (11684866)
2001
8
Four cases of bleeding diathesis in children due to congenital plasminogen activator inhibitor-1 deficiency. (10754381)
1999
9
Molecular pathogenesis of type I congenital plasminogen deficiency: expression of recombinant human mutant plasminogens in mammalian cells. (8978291)
1997
10
A novel missense mutation in two families with congenital plasminogen deficiency: identification of an Ala675 to Thr675 substitution. (8713786)
1996
11
A patient with congenital plasminogen deficiency manifesting primary pulmonary hypertension. (8358126)
1993
12
Congenital plasminogen deficiency caused by a Ser-572 to Pro mutation. (8392398)
1993
13
Unusual thrombotic-like retinopathy (Coats' disease) associated with congenital plasminogen deficiency type I. (8258756)
1993
14
Type I congenital plasminogen deficiency is not a risk factor for thrombosis. (1621238)
1992
15
Congenital plasminogen deficiency associated with venous thromboembolism: therapeutic trial with stanozolol. (3730296)
1986

Genetic Variations for Congenital Plasminogen Deficiency

Expression for genes affiliated with Congenital Plasminogen Deficiency

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Congenital Plasminogen Deficiency

Search GEO for disease gene expression data for Congenital Plasminogen Deficiency.

Pathways for genes affiliated with Congenital Plasminogen Deficiency

Compounds for genes affiliated with Congenital Plasminogen Deficiency

GO Terms for genes affiliated with Congenital Plasminogen Deficiency

Products for genes affiliated with Congenital Plasminogen Deficiency

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Congenital Plasminogen Deficiency

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet