MCID: CNG033
MIFTS: 34

Congenital Syphilis malady

Infectious diseases, Bone diseases, Neuronal diseases categories

Summaries for Congenital Syphilis

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Wikipedia:63 Congenital syphilis is syphilis present in utero and at birth, and occurs when a child is born to a... more...

MalaCards based summary: Congenital Syphilis, also known as syphilis, congenital, is related to thrombocytopenia and hepatitis. An important gene associated with Congenital Syphilis is ABCB7 (ATP-binding cassette, sub-family B (MDR/TAP), member 7). The compounds ursodeoxycholic acid and pravastatin have been mentioned in the context of this disorder. Affiliated tissues include bone, eye and brain.

Disease Ontology:9 A syphilis that results in a multisystem infection in the fetus via the placenta.

Aliases & Classifications for Congenital Syphilis

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Sources:
9Disease Ontology, 43Novoseek, 60UMLS, 55SNOMED-CT, 33MeSH, 27ICD9CM, 38NCIt, 25ICD10
See all sources

Congenital Syphilis, Aliases & Descriptions:

Name: Congenital Syphilis 9
Syphilis, Congenital 60
 
Syphilis Congenital 43


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Bone diseases, Neuronal diseases


External Ids:

Disease Ontology9 DOID:9856
MeSH33 D013590
ICD9CM27 090.9, 090
NCIt38 C84649
ICD1025 A50

Related Diseases for Congenital Syphilis

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Graphical network of the top 20 diseases related to Congenital Syphilis:



Diseases related to congenital syphilis

Symptoms for Congenital Syphilis

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Drugs & Therapeutics for Congenital Syphilis

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Drug clinical trials:

Search ClinicalTrials for Congenital Syphilis

Search NIH Clinical Center for Congenital Syphilis

Genetic Tests for Congenital Syphilis

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Anatomical Context for Congenital Syphilis

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MalaCards organs/tissues related to Congenital Syphilis:

31
Bone, Eye, Brain, Placenta, Testes, Skin, Liver, Tongue, Pituitary

Animal Models for Congenital Syphilis or affiliated genes

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Publications for Congenital Syphilis

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Articles related to Congenital Syphilis:

(show top 50)    (show all 532)
idTitleAuthorsYear
1
Congenital syphilis investigation processes and timing in Louisiana. (25118972)
2014
2
Congenital syphilis, still a reality. (23919058)
2013
3
Incidence of congenital syphilis in Brazil and its relationship with the Family Health Strategy. (22635036)
2012
4
Disseminated intravascular coagulation with intracranial haematoma in neonatal congenital syphilis. (20889622)
2011
5
Congenital syphilis, RAcunion Island, 2010. (22099109)
2011
6
Congenital syphilis: still a serious, under-diagnosed threat for children in resource-poor countries. (20490768)
2010
7
Cost-effectiveness of on-site antenatal screening to prevent congenital syphilis in rural eastern Cape Province, Republic of South Africa. (17308502)
2007
8
Managing congenital syphilis again? The more things change ... (17471033)
2007
9
Is congenital syphilis really congenital syphilis? (17485812)
2006
10
Detection and follow up of infants at risk of congenital syphilis. (16790724)
2006
11
Congenital syphilis--United States, 2002. (15306757)
2004
12
The prevention and management of congenital syphilis: an overview and recommendations. (15356934)
2004
13
Survival with hypopituitarism from congenital syphilis. (11927736)
2002
14
Congenital syphilis after maternal treatment for syphilis during pregnancy. (11904625)
2002
15
Unusual presentation of congenital syphilis. (10945059)
2000
16
Haemophagocytosis in early congenital syphilis. (10412813)
1999
17
Congenital syphilis: subtle presentation of fulminant disease. (9039217)
1997
18
New approaches to syphilis control. Finding opportunities for syphilis treatment and congenital syphilis prevention in a women's correctional setting. (9101633)
1997
19
Immune abnormalities in guinea pigs with asymptomatic congenital syphilis. (9396560)
1997
20
Congenital syphilis: still a reality in 1996. (8890847)
1996
21
Diagnosis of congenital syphilis from placental examination: comparison of histopathology, Steiner stain, and polymerase chain reaction for Treponema pallidum DNA. (8617480)
1996
22
A blood-result turn-around time survey to improve congenital syphilis prevention in a rural area. (8685786)
1996
23
Congenital syphilis and STD surveillance. (7809784)
1994
24
Neonatal hypoglycemia caused by hypopituitarism in infants with congenital syphilis. (8229534)
1993
25
Diagnosis of congenital syphilis by combining Treponema pallidum-specific IgM detection with immunofluorescent antigen detection for T. pallidum. (8515119)
1993
26
The diagnosis and management of maternal and congenital syphilis. (1538267)
1992
27
Radiologic case study. Congenital syphilis. (1508775)
1992
28
Characteristics of mothers of live infants with congenital syphilis in Florida, 1987-1989. (1442732)
1992
29
Congenital syphilis criteria. (1983907)
1991
30
Relative placental weight in congenital syphilis. (2326235)
1990
31
Congenital syphilis. (2274080)
1990
32
Congenital syphilis--breaking through the safety net. (2215621)
1990
33
Early and congenital syphilis. (2687743)
1989
34
Unusual bone changes and laboratory features in congenital syphilis. (2583817)
1989
35
Congenital syphilis and necrotizing funisitis. (2754789)
1989
36
Congenital syphilis in Mocambique: the diagnostic complementary role of laboratory and radiological investigations. (2485711)
1989
37
Congenital syphilis and necrotizing funisitis. (2918676)
1989
38
Leads from the MMWR. Syphilis and congenital syphilis--United States, 1985-1988. (3411729)
1988
39
Repair of a palatal defect associated with late congenital syphilis using a tongue flap. (3276855)
1988
40
Congenital syphilis--a plea for prevention. (3420474)
1988
41
Congenital syphilis. Why is it still occurring? (6471297)
1984
42
Marshall syndrome: a condition resembling congenital syphilis. (7214117)
1981
43
Membranous glomerulonephritis in congenital syphilis. (383337)
1979
44
Congenital syphilis of the eye with lens involvement. (350202)
1978
45
Transplacental transmission of spirochetes in congenital syphilis: a new perspective. (725705)
1978
46
Value of bone roentgenograms in diagnosis. Congenital syphilis with unusual clinical presentations. (16848)
1977
47
Some aspects of congenital syphilis. (1228134)
1975
48
Congenital syphilis. (4489969)
1973
49
Glomerulopathy of congenital syphilis. (4702912)
1973
50
Nephropathy of congenital syphilis. (4270175)
1973

Variations for Congenital Syphilis

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Expression for genes affiliated with Congenital Syphilis

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Search GEO for disease gene expression data for Congenital Syphilis.

Pathways for genes affiliated with Congenital Syphilis

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Compounds for genes affiliated with Congenital Syphilis

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Compounds related to Congenital Syphilis according to GeneCards Suite gene sharing:

(show all 11)
idCompoundScoreTop Affiliating Genes
1ursodeoxycholic acid43 24 1211.4CD40LG, ABCB7
2pravastatin43 49 28 24 1213.4CD40LG, ABCB7
3thyroxine43 2410.3ABCB7, CD40LG
4fibrinogen439.3CD40LG, ABCB7
5lactate439.3CD40LG, ABCB7
6creatinine439.2ABCB7, CD40LG
7aspartate439.2CD40LG, ABCB7
8heparin43 28 24 1212.1CD40LG, ABCB7
9alanine439.1CD40LG, ABCB7
10testosterone43 59 24 1212.0ABCB7, CD40LG
11glutamate438.8CD40LG, ABCB7

GO Terms for genes affiliated with Congenital Syphilis

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Products for genes affiliated with Congenital Syphilis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Congenital Syphilis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet