MCID: CNG033
MIFTS: 39

Congenital Syphilis malady

Categories: Infectious diseases, Neuronal diseases, Bone diseases

Aliases & Classifications for Congenital Syphilis

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Aliases & Descriptions for Congenital Syphilis:

Name: Congenital Syphilis 11 13
Syphilis, Congenital 39 68
 
Syphilis Congenital 50

Classifications:



External Ids:

Disease Ontology11 DOID:9856
ICD1030 A50, A50.9
ICD9CM32 090, 090.9
MeSH39 D013590
NCIt45 C84649

Summaries for Congenital Syphilis

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Wikipedia:71 Congenital syphilis is syphilis present in utero and at birth, and occurs when a child is born to a... more...

MalaCards based summary: Congenital Syphilis, also known as syphilis, congenital, is related to syphilis and late congenital syphilis, and has symptoms including syphilitic chancre An important gene associated with Congenital Syphilis is CD40LG (CD40 Ligand), and among its related pathways is Primary immunodeficiency. Affiliated tissues include bone, eye and brain.

Disease Ontology:11 A syphilis that results in a multisystem infection in the fetus via the placenta.

Related Diseases for Congenital Syphilis

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Diseases in the Syphilis family:

Early Congenital Syphilis Late Congenital Syphilis
Primary Syphilis Secondary Syphilis
congenital syphilis

Diseases related to Congenital Syphilis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 203)
idRelated DiseaseScoreTop Affiliating Genes
1syphilis31.4CD40LG, CD79A, EXTL3
2late congenital syphilis12.3
3early congenital syphilis12.2
4alcoholic neuropathy10.2CD40LG, CD79A
5camptodactyly vertebral fusion10.2CD40LG, CD79A
6spinal polio10.2CD40LG, CD79A
7rabies10.2CD40LG, CD79A
8unilateral retinoblastoma10.2CD40LG, CD79A
9mesangial proliferative glomerulonephritis10.2CD40LG, CD79A
10delta chain disease10.2CD40LG, CD79A
11discitis10.2CD40LG, CD79A
12spinal canal and spinal cord meningioma10.2CD40LG, CD79A
13trichostrongyloidiasis10.2CD40LG, CD79A
14colloid adenoma10.2CD40LG, CD79A
15heart septal defect10.2CD40LG, CD79A
16cutaneous polyarteritis nodosa10.2CD40LG, CD79A
17retinal microaneurysm10.2CD40LG, CD79A
18pediatric meningioma10.2CD40LG, CD79A
19tonsil cancer10.2CD40LG, CD79A
20indomethacin antenatal infection10.2CD40LG, CD79A
21postcricoid region cancer10.2CD40LG, CD79A
22beach ear10.2CD40LG, CD79A
23acute kidney tubular necrosis10.2CD40LG, CD79A
24atheroembolism of kidney10.2CD40LG, CD79A
25partial sensory epilepsy10.2CD40LG, CD79A
26ritscher-schinzel syndrome 110.2CD40LG, CD79A
27diabetic angiopathy10.2CD40LG, CD79A
28endocarditis10.2CD40LG, CD79A
29dumping syndrome10.2CD40LG, CD79A
30striatonigral degeneration10.2CD40LG, CD79A
31ciliary body spindle cell melanoma10.2CD40LG, CD79A
32purulent endophthalmitis10.2CD40LG, CD79A
33mu chain disease10.2CD40LG, CD79A
34generalized atherosclerosis10.2CD40LG, CD79A
35bursitis10.2CD40LG, CD79A
36homocystinuria10.2CD40LG, CD79A
37mental retardation, autosomal dominant 1910.2CD40LG, CD79A
38hemangioma of orbit10.2CD40LG, CD79A
39leiomyosarcoma10.2CD40LG, CD79A
40immunoglobulin beta deficiency10.2CD40LG, CD79A
41gestational diabetes10.2CD40LG, CD79A
42odontogenic myxoma10.2CD40LG, CD79A
43chronic mucocutaneous candidiasis10.2CD40LG, CD79A
44alkhurma hemorrhagic fever10.2CD40LG, CD79A
45pedophilia10.2CD40LG, CD79A
46polyneuropathy due to drug10.2CD40LG, CD79A
47colonic benign neoplasm10.2CD40LG, CD79A
48cutaneous ganglioneuroma10.2CD40LG, CD79A
49ovarian serous cystadenocarcinoma10.2CD40LG, CD79A
50coronary artery dissection, spontaneous10.2CD40LG, CD79A

Graphical network of the top 20 diseases related to Congenital Syphilis:



Diseases related to congenital syphilis

Symptoms & Phenotypes for Congenital Syphilis

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UMLS symptoms related to Congenital Syphilis:


syphilitic chancre

Drugs & Therapeutics for Congenital Syphilis

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Drugs for Congenital Syphilis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
chloroquineapproved, vet_approvedPhase 314954-05-72719
Synonyms:
( -)-Chloroquine
(+)-Chloroquine
(-)-Chloroquine
(R)-(-)-Chloroquine
3377 RP opalate
3545-67-3
50-63-5
54-05-7
56598-66-4
58175-86-3
58175-87-4
7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline
7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline
AB00053436
AC1L1EB8
AC1Q2ZA7
AC1Q2ZA8
Amokin
Aralen
Aralen HCl
Arechin
Arechine
Arequin
Arolen
Arthrochin
Artrichin
Avlochlor
Avloclor
BPBio1_000655
BRD-A91699651-065-01-1
BRN 0482809
BSPBio_000595
BSPBio_002001
Bemaco
Bemaphate
Bemasulph
Benaquin
Bipiquin
C07625
C18H26ClN3
CCRIS 3439
CHEBI:3638
CHEMBL76
CID2719
CQ
CU-01000012392-2
Capquin
Chemochin
Chingamin
Chloraquine
Chlorochin
Chlorochine
Chlorochinum
Chloroin
Chloroquin
Chloroquina
Chloroquine
Chloroquine (USP/INN)
Chloroquine (VAN)
Chloroquine Bis-Phosphoric Acid
Chloroquine Phosphate
Chloroquine [USAN:INN:BAN]
Chloroquine phosphate
Chloroquinium
Chloroquinum
Chloroquinum [INN-Latin]
Chlorquin
Cidanchin
Clorochina
Clorochina [DCIT]
Cloroquina
Cloroquina [INN-Spanish]
Cocartrit
D02366
DB00608
Dawaquin
Delagil
Dichinalex
DivK1c_000404
EINECS 200-191-2
Elestol
Gontochin
Gontochin phosphate
HMS2090O03
HSDB 3029
Heliopar
Hydroxychloroquine Sulfate
IDI1_000404
Imagon
 
Ipsen 225
Iroquine
KBio1_000404
KBio2_000592
KBio2_003160
KBio2_005728
KBio3_001221
KBioGR_000778
KBioSS_000592
Khingamin
Klorokin
LS-141726
Lapaquin
Lopac0_000296
Malaquin
Malaquin (*Diphosphate*)
Malaren
Malarex
Mesylith
Miniquine
MolMap_000009
MolPort-001-783-623
N(4)-(7-chloro-4-Quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine
N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
N4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine
NCGC00015256-04
NCGC00162120-01
NCI60_000894
NINDS_000404
NSC 187208
NSC14050
NSC187208
Neochin
Nivachine
Nivaquine
Nivaquine B
Pfizerquine
Plaquenil
Prestwick0_000548
Prestwick1_000548
Prestwick2_000548
Prestwick3_000548
Quinachlor
Quinagamin
Quinagamine
Quinercyl
Quingamine
Quinilon
Quinoscan
RP 3377
RP-3377
Resochen
Resochin
Resoquina
Resoquine
Reumachlor
Reumaquin
Rivoquine
Ro 01-6014/N2
Ronaquine
Roquine
SMP2_000034
SN 6718
SN-7618
SPBio_000174
SPBio_002516
ST 21
ST 21 (pharmaceutical)
Sanoquin
Silbesan
Siragan
Solprina
Sopaquin
Spectrum2_000127
Spectrum3_000341
Spectrum4_000279
Spectrum5_000707
Spectrum_000132
Tanakan
Tanakene
Tresochin
Trochin
UNII-886U3H6UFF
W 7618
WIN 244
WLN: T66 BNJ EMY1&3N2&2 IG
chloroquine
nchembio.215-comp4
nchembio.368-comp8
nchembio.87-comp17
{4-[(7-chloroquinolin-4-yl)amino]pentyl}diethylamine
2
AzithromycinapprovedPhase 334683905-01-555185, 53477736, 447043
Synonyms:
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*
121470-24-4
75199_FLUKA
83905-01-5
9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A
AC-16014
AC1L9KEG
Aritromicina
Azasite
Azenil
Azifast
Azigram
Azimakrol
Azithramycine
Azithromycin
Azithromycin & Tumor Necrosis Factor
Azithromycin (AIDS Initiative)
Azithromycin (anhydrous)
Azithromycin Dihydrate
Azithromycin Monohydrate
Azithromycin Sterile
Azithromycin dihydrate
Azithromycin plus Tumor Necrosis Factor
Azithromycine
Azithromycine [French]
Azithromycinum
Azithromycinum [Latin]
Azitrocin
Azitromax
Azitromicina
Azitromicina [Spanish]
Azitromin
Azythromycin
BIDD:GT0792
BRN 5387583
BSPBio_002285
Bio-0676
C38H72N2O12
CCRIS 1961
CHEBI:2955
CHEMBL529
CID447043
CP-62993
CP62,993
CPD000471864
DCH3
DRG-0104
 
DivK1c_000233
HMS1922G12
HMS2094M11
HMS500L15
HSDB 7205
Hemomycin
IDI1_000233
KBio1_000233
KBio2_000787
KBio2_003355
KBio2_005923
KBio3_001505
KBioGR_000731
KBioSS_000787
LS-1834
MLS001055353
MLS001066331
MLS001201763
MLS001304005
MLS001332499
MLS001332500
Misultina
MolPort-002-507-426
N,N-Dimethyl-4-amino-benzaldehyde
NCGC00090753-01
NCGC00090753-02
NINDS_000233
NSC643732
SAM002589961
SMR000471864
SPBio_001544
SPECTRUM1503679
Spectrum2_001582
Spectrum3_000653
Spectrum4_000186
Spectrum5_001867
Spectrum_000307
Sumamed
Tromix
UNII-JTE4MNN1MD
XZ-450
Z-Pak
ZIT
Zentavion
Zithromac
Zithromax
Zithromax IV
Zithromycin
Zitromax
Zitromax Avium 600
Zmas
Zmax
azithromycin
3
SulfadoxineapprovedPhase 31322447-57-617134
Synonyms:
2447-57-6
4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
4-Sulfanilamido-5,6-dimethoxypyrimidine
4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
4-amino-N-[5,6-bis(methyloxy)pyrimidin-4-yl]benzenesulfonamide
46810_RIEDEL
5-25-13-00306 (Beilstein Handbook Reference)
6-(4-Aminobenzenesulfonamido)-4,5-dimethoxypyrimidine
AB00514044
AC-11921
AC1L29DT
AC1Q46GG
Ambap2447-57-6
BPBio1_001286
BRD-K55250441-001-03-1
BRN 0625453
BSPBio_001168
C07630
CAS-2447-57-6
CHEBI:9329
CHEMBL1539
CID17134
D00580
DB01299
EINECS 219-504-9
Fanasil
Fanzil
HMS1571K10
HMS2090P07
HMS2094C19
I09-0529
LS-31247
MLS002154150
MolPort-003-850-341
N'-(5,6-Dimethoxy-4-pyrimidyl)sulfanilamide
N(sup 1)-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
 
N1-(5,6-Dimethoxy-4-pyrimidinyl)sulfanilamide
NCGC00016612-01
NCGC00016612-02
Orthosulfin
Prestwick0_001094
Prestwick1_001094
Prestwick2_001094
Prestwick3_001094
Ro 4-4393
Ro-4-4393
S2511_Selleck
S7821_SIGMA
SMR000857259
SPBio_003054
SULFADOXINE
Sanasil: Sulfadoxine: Sulformetoxin
Solfadossina
Solfadossina [DCIT]
Sulfadoxin
Sulfadoxina
Sulfadoxina [INN-Spanish]
Sulfadoxine
Sulfadoxine (JAN/USP/INN)
Sulfadoxine [USAN:INN:BAN:JAN]
Sulfadoxinum
Sulfadoxinum [INN-Latin]
Sulformethoxine
Sulformetoxine
Sulforthomidine
Sulphadoxine
Sulphormethoxine
Sulphormetoxin
Sulphorthodimethoxine
UNII-88463U4SM5
WR 4073
WR 4873
ZINC00002094
4
Pyrimethamineapproved, vet_approvedPhase 315758-14-04993
Synonyms:
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
46706_FLUKA
46706_RIEDEL
4753 R.P.
4753 r.p
5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE
5-(4-CHLOROPHENYL)-6-ETHYL-2,4-PYRIMIDINEDIAMINE
5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidi nediamine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
5-(4-chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
5-(p-chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-[4-Chlorophenyl]-6-ethyl-2,4-pyrimidinediamine
58-14-0
AB00052084
AC-7879
AC1L1JDI
AI3-25005
AZT + Pyrimethamine combination
Aventis Brand of Pyrimethamine
BIDD:GT0149
BIDD:PXR0173
BPBio1_000147
BRD-K88429204-001-05-4
BRN 0219864
BSPBio_000133
BSPBio_003282
BW 50-63
BW 5063
C07391
C12H13ClN4
CAS-58-14-0
CCRIS 546
CD
CHEBI:8673
CHEMBL36
CID4993
CP6
CPD000058714
CRL-8131 & Pyrimethamine
CRL-8142 & Pyrimethamine
Chloridin
Chloridine
Chloridyn
D00488
D011739
DB00205
Darachlor
Daraclor
Darapram
Daraprim
Daraprim (TN)
Daraprime
Daraprin
Diaminopyritamin
Disulone
DivK1c_000652
EINECS 200-364-2
EXR-101
Erbaprelina
Ethylpyrimidine
Fansidar
Fansidar (Pyrimethamine/Sulfadoxine)
Glaxo Wellcome Brand of Pyrimethamine
GlaxoSmithKline Brand of Pyrimethamine
HMS1568G15
HMS1920N12
HMS2092E13
HMS502A14
IDI1_000652
KBio1_000652
KBio2_001386
KBio2_003954
 
KBio2_006522
KBio3_002502
KBioGR_001007
KBioSS_001386
Khloridin
L000713
LS-238
Lactoferrin B & Pyrimethamine
Lactoferrin H & Pyrimethamine
MCB-3837
MLS000028606
MLS001148621
MLS002454446
MLS002701881
Malacid
Malocid
Malocide
Maloprim
MolPort-001-783-655
NCGC00016256-01
NCGC00016256-02
NCGC00023188-03
NCGC00023188-04
NCGC00023188-05
NCGC00023188-06
NCGC00023188-07
NCI-C01683
NCI60_002604
NCIOpen2_008313
NINDS_000652
NSC 3061
NSC-3061
NSC3061
Oxaquin
Pirimecidan
Pirimetamin
Pirimetamina
Pirimetamina [INN-Spanish]
Pirimetamina [Spanish]
Prestwick0_000037
Prestwick1_000037
Prestwick2_000037
Prestwick3_000037
Prestwick_504
Primethamine
Pyremethamine
Pyrimethamin
Pyrimethamine (JAN/USP/INN)
Pyrimethamine (Pyr)
Pyrimethamine Hcl
Pyrimethamine [USAN:INN:BAN:JAN]
Pyrimethaminum
Pyrimethaminum [INN-Latin]
RP 4753
S2006_Selleck
SAM002554921
SMR000058714
SPBio_000672
SPBio_002054
SPECTRUM1500520
Spectrum2_000886
Spectrum3_001701
Spectrum4_000494
Spectrum5_001447
Spectrum_000906
TCMDC-123831
TCMDC-125860
Tindurin
Tindurine
Tinduring
UNII-Z3614QOX8W
WLN: T6N CNJ BZ DZ ER DG& F2
WR 2978
Wellcome Brand of Pyrimethamine
ZINC00057464
m alocid
nchembio.215-comp13
nchembio.87-comp22
pyrimethamine
5
Folic Acidapproved, nutraceutical, vet_approvedPhase 3439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
6
leucovorinapproved, NutraceuticalPhase 3323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
7VaccinesPhase 36611
8Heptavalent Pneumococcal Conjugate VaccinePhase 3465
9mometasone furoatePhase 317883919-23-7
10Fanasil, pyrimethamine drug combinationPhase 3122
11Folic Acid AntagonistsPhase 32257
12Peripheral Nervous System AgentsPhase 323689
13Vitamin B ComplexPhase 34337
14Renal AgentsPhase 3754
15Chloroquine diphosphatePhase 314950-63-5
16Antirheumatic AgentsPhase 310956
17AnthelminticsPhase 3446
18Analgesics, Non-NarcoticPhase 36501
19AnalgesicsPhase 311733
20Anti-Inflammatory AgentsPhase 310729
21Anti-Infective AgentsPhase 322062
22Anti-Inflammatory Agents, Non-SteroidalPhase 34443
23Antiparasitic AgentsPhase 32199
24Antiprotozoal AgentsPhase 32051
25AntimalarialsPhase 31246
26Vitamin B9NutraceuticalPhase 34392
27FolateNutraceuticalPhase 34392
28
Penicillin Gapproved, vet_approved3161-33-65904
Synonyms:
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(5R,6R)-Benzylpenicillin
(Phenylmethyl)penicillin
(Phenylmethyl)penicillinic acid
113-98-4 (mono-potassium salt)
2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylate
2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylic acid
4-27-00-05861 (Beilstein Handbook Reference)
46609_FLUKA
46609_RIEDEL
6-(2-Phenylacetamido)penicillanic acid
6-(2-phenylacetamido)penicillanic acid
61-33-6
69-57-8 (mono-hydrochloride salt)
AB00384263
AC-14408
AC1L1LDX
AC1LD0NQ
AC1Q2CBJ
AR-1K9813
Abbocillin
Ayercillin
BPBio1_001206
BRD-K55191674-236-03-7
BRD-K55191674-237-02-7
BRN 0044740
BSPBio_001096
BSPBio_002183
Bencilpenicilina
Bencilpenicilina [Spanish]
Benzopenicillin
Benzyl penicillin
Benzyl-6-aminopenicillinic acid
Benzylpenicillin
Benzylpenicillin (INN)
Benzylpenicillin G
Benzylpenicillin [INN:BAN]
Benzylpenicillin potassium
Benzylpenicillin potassium (JP15)
Benzylpenicillin potassium salt
Benzylpenicilline
Benzylpenicilline [French]
Benzylpenicillinic acid
Benzylpenicillinum
Benzylpenicillinum [Latin]
BenzylpƩnicilline
Bicillin
Bicillin (*Benzathine Salt, Tetrahydrate*)
Bio-0602
C05551
C16H18N2O4S
CHEBI:18208
CHEBI:51354
CHEBI:7963
CHEMBL1223
CHEMBL29
CID443084
CID5904
CID640429
Cillora
Cilloral
Cilopen
Compocillin G
Cosmopen
Crysticillin 300 A.S.
D01053
D02336
DB01053
DivK1c_000316
Dropcillin
EINECS 200-506-3
Free benzylpenicillin
Free penicillin G
Free penicillin II
Galofak
Gelacillin
HMS1920F12
HMS2091N12
 
HMS500P18
HSDB 3166
I06-1083
IDI1_000316
KBio1_000316
KBio2_001413
KBio2_003981
KBio2_006549
KBio3_001683
KBioGR_000942
KBioSS_001413
LS-149836
LS-195224
Liquacillin
MLS000069426
MLS000766897
MLS001032123
MLS001076462
MLS001173382
Megacillin
MolPort-002-511-679
MolPort-003-666-255
NCGC00021679-03
NCGC00021679-04
NCGC00159348-02
NChemBio.2007.21-comp4
NINDS_000316
NSC 193396
P1772
P7794_SIGMA
P8721_SIAL
PCG
PENICILLIN-G
PENK_SIAL
PENK_SIGMA
PG
PNN
Pencillin G
Penicillin
Penicillin G
Penicillin G potassium
Penicillin G potassium (USP)
Penicillin G potassium salt
Penicillin potassium G, crystalline
Penicillin-G potassium
Pfizerpen
Pfizerpen (TN)
Pharmacillin
Phenylacetamidopenicillanic acid
Phenylacetyl-6-aminopenicillanic acid
Pradupen
Prestwick0_001078
Prestwick1_001078
Prestwick2_001078
Prestwick3_001078
SMR000059004
SMR000538912
SPBio_000475
SPBio_002998
SPECTRUM1500465
ST51052951
Sodium benzylpenicillin
Sodium penicillin
Specilline G
Spectrum2_000518
Spectrum3_000542
Spectrum4_000471
Spectrum5_001108
Spectrum_000933
UNII-Q42T66VG0C
Ursopen
ZINC03871701
bensylpenicillin
benzyl benicillin
benzylpenicilline potassique
nchembio.177-comp1
nchembio.252-comp1
penicillin g
potassium 2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylate
29penicillins114
30Penicillin G Procaine31
31Penicillin G Benzathine31

Interventional clinical trials:

idNameStatusNCT IDPhase
1Protecting From Pneumococcus in Early Life (The PROPEL Trial)RecruitingNCT02628886Phase 3
2Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In AfricaTerminatedNCT01103063Phase 3
3Preventing Congenital SyphilisRecruitingNCT02353117

Search NIH Clinical Center for Congenital Syphilis


Cochrane evidence based reviews: syphilis, congenital

Genetic Tests for Congenital Syphilis

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Anatomical Context for Congenital Syphilis

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MalaCards organs/tissues related to Congenital Syphilis:

36
Bone, Eye, Brain, Placenta, Testes, Skin, Liver

Publications for Congenital Syphilis

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Articles related to Congenital Syphilis:

(show top 50)    (show all 575)
idTitleAuthorsYear
1
Infectious and congenital syphilis notifications associated with an ongoing outbreak in northern Australia. (27080030)
2016
2
Infant Deaths Due To Herpes Simplex Virus, Congenital Syphilis, and HIV in New York City. (26933212)
2016
3
Evaluation of the management of pregnancies and infants at risk for congenital syphilis: La RAcunion, 2008 to 2014. (27711044)
2016
4
Cuba Validated as the First Country to Eliminate Mother-to-Child Transmission of Human Immunodeficiency Virus and Congenital Syphilis: Lessons Learned from the Implementation of the Global Validation Methodology. (27835624)
2016
5
Syphilis in Pregnancy and Congenital Syphilis: Why Can We not yet Face This Problem? (27756083)
2016
6
The sins of the fathers will be visited upon the children": Congenital syphilis and leg braces pictorial depiction in eighteenth century Britain. (27421914)
2016
7
Characterization and six-month follow-up on a cohort of newborns with congenital syphilis. (27622443)
2016
8
Global burden of maternal and congenital syphilis in 2008 and 2012: a health systems modelling study. (27443780)
2016
9
Skin rash: a manifestation of early congenital syphilis. (27268292)
2016
10
The Cuban Experience in the Elimination of Mother-to-Child Transmission of Congenital Syphilis. (27715301)
2016
11
In time: the persistence of congenital syphilis in Brazil - More progress needed! (27521453)
2016
12
Congenital syphilis in the era of decreasing seroprevalence. (26776135)
2016
13
Diagnosing congenital syphilis using Hutchinson's method: Differentiating between syphilitic, mercurial, and syphilitic-mercurial dental defects. (26696588)
2016
14
Early Postnatal Diagnosis of Congenital Syphilis: Contribution of a Comparative Western Blot Method. (26961856)
2016
15
Eliminating congenital syphilis-lessons learnt in the United Kingdom should inform global strategy. (27102071)
2016
16
A Case Report and Review of Early Symptomatic Congenital Syphilis Clinical Variations. (26976805)
2016
17
Underreporting of Congenital Syphilis as a Cause of Fetal and Infant Deaths in Northeastern Brazil. (27941983)
2016
18
Dental Stigmata of Congenital Syphilis: A Historic Review With Present Day Relevance. (26897633)
2016
19
The incidence of congenital syphilis in the United Kingdom: February 2010 to January 2015. (26931054)
2016
20
Maternal and congenital syphilis, underreported and difficult to control. (27167649)
2016
21
Wimberger Sign in Congenital Syphilis. (26427966)
2015
22
31-Week Premature Male with Congenital Syphilis. (26689031)
2015
23
Increase in Incidence of Congenital Syphilis - United States, 2012-2014. (26562206)
2015
24
Canadian Public Health Laboratory Network laboratory guidelines for congenital syphilis and syphilis screening in pregnant women in Canada. (25798162)
2015
25
Dental stigmata and enamel thickness in a probable case of congenital syphilis from XVI century Croatia. (26263543)
2015
26
A tryst with a dysmorphic parturient with congenital syphilis. (25838595)
2015
27
Symptomatic Early Congenital Syphilis: ACommon but Forgotten Disease. (26522203)
2015
28
Congenital Syphilis: Trends in Mortality and Morbidity in the United States, 1999-2013. (26470826)
2015
29
Maternal and congenital syphilis in selected Latin America and Caribbean countries: a multi-country analysis using data from the Perinatal Information System. (25725563)
2015
30
Recent change in congenital syphilis in Korea: A retrospective study of 10a88years. (25916174)
2015
31
A review of the guidelines for the evaluation and treatment of congenital syphilis. (25996197)
2015
32
Notification and management of congenital syphilis in the Northern Territory 2009 to 2014. (26620345)
2015
33
Over reporting of congenital syphilis in Guangzhou, China. (25587890)
2015
34
Congenital syphilis presenting as Jarisch-Herxheimer reaction at birth. (25868945)
2015
35
Recurrent Fever, Anemia, Arthralgia, and Genu Varum as Late Manifestations of Congenital Syphilis. (26587855)
2015
36
Congenital syphilis: Marching toward elimination. (26392646)
2015
37
A probable case of congenital syphilis from pre-Columbian Austria. (26482430)
2015
38
Prenatal diagnosis of congenital syphilis presenting with transient pleural effusion in the fetus: a case report and rising incidence of congenital syphilis in South Korea. (26753496)
2015
39
Republication: Two Premature Neonates of Congenital Syphilis with Severe Clinical Manifestations. (26543391)
2015
40
Syphilis in pregnancy and congenital syphilis in Amazonas State, Brazil: an evaluation using database linkage. (24896047)
2014
41
Finding a needle in the haystack: the costs and cost-effectiveness of syphilis diagnosis and treatment during pregnancy to prevent congenital syphilis in Kalomo District of Zambia. (25478877)
2014
42
Early detection of congenital syphilis. (25231043)
2014
43
Incidence of congenital syphilis in the South Region of Brazil. (24861290)
2014
44
Coexistence of congenital syphilis and cytomegalovirus infection: a case report. (25230065)
2014
45
Risk factors for congenital syphilis and adverse pregnancy outcomes in offspring of women with syphilis in Shenzhen, China: a prospective nested case-control study. (24326577)
2014
46
Maternal and congenital syphilis in Karnataka, India. (24968685)
2014
47
50 years ago in the journal of pediatrics: congenital syphilis: a laid ghost walks. (24359901)
2014
48
Evaluation of preventative and control measures for congenital syphilis in State of Mato Grosso. (25075485)
2014
49
Synthesized prevention and control of one decade for mother-to-child transmission of syphilis and determinants associated with congenital syphilis and adverse pregnancy outcomes in Shenzhen, South China. (24973132)
2014
50
Congenital syphilis investigation processes and timing in Louisiana. (25118972)
2014

Variations for Congenital Syphilis

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Expression for genes affiliated with Congenital Syphilis

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Search GEO for disease gene expression data for Congenital Syphilis.

Pathways for genes affiliated with Congenital Syphilis

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Pathways related to Congenital Syphilis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.6CD40LG, CD79A

GO Terms for genes affiliated with Congenital Syphilis

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Biological processes related to Congenital Syphilis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1B cell differentiationGO:003018310.0CD40LG, CD79A
2B cell proliferationGO:00421009.6CD40LG, CD79A

Sources for Congenital Syphilis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet