MCID: CNG021
MIFTS: 42

Congenital Toxoplasmosis malady

Categories: Rare diseases, Fetal diseases, Neuronal diseases, Infectious diseases

Aliases & Classifications for Congenital Toxoplasmosis

About this section
Sources:
10Disease Ontology, 45NIH Rare Diseases, 12DISEASES, 51Orphanet, 47Novoseek, 36MeSH, 65UMLS, 27ICD10, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Congenital Toxoplasmosis:

Name: Congenital Toxoplasmosis 10 45 12 51
Toxoplasmosis, Congenital 36 65
Toxoplasma Embryofetopathy 51
 
Toxoplasmosis Congenital 47
Toxoplasmosis - Congen. 10
Toxoplasma Embryopathy 51

Characteristics:

Orphanet epidemiological data:

51
congenital toxoplasmosis:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe),1-5/10000 (United States); Age of onset: Adolescent,Adult,Antenatal,Childhood,Infancy,Neonatal

Classifications:



External Ids:

Disease Ontology10 DOID:13336
ICD1027 P37.1
MeSH36 D014125
NCIt42 C50503
Orphanet51 858
ICD10 via Orphanet28 P37.1
MESH via Orphanet37 D014125
UMLS via Orphanet66 C0040560
UMLS65 C0040560

Summaries for Congenital Toxoplasmosis

About this section
Disease Ontology:10 A toxoplasmosis that involves a reactivated infection of the mother transmitted to the fetus during pregnancy. Spontaneous abortion and stillbirth may occur.

MalaCards based summary: Congenital Toxoplasmosis, also known as toxoplasmosis, congenital, is related to purpura and cryoglobulinemia, and has symptoms including premature birth, abnormality of retinal pigmentation and visual impairment. An important gene associated with Congenital Toxoplasmosis is CD40LG (CD40 Ligand), and among its related pathways are Primary immunodeficiency and T Cell Co-Signaling Pathway: Ligand-Receptor Interactions. Affiliated tissues include breast, liver and eye.

Related Diseases for Congenital Toxoplasmosis

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Diseases in the Toxoplasmosis family:

congenital toxoplasmosis

Diseases related to Congenital Toxoplasmosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 449)
idRelated DiseaseScoreTop Affiliating Genes
1purpura30.4CD40LG, CD79A
2cryoglobulinemia30.1CD40LG, CD79A
3cystitis30.0CD40LG, CD79A
4angioedema30.0CD40LG, CD79A
5adenocarcinoma30.0CD40LG, CD79A
6hepatitis10.4
7toxoplasmosis10.4
8endotheliitis10.3
9prostatitis10.3
10cerebritis10.3
11pancreatitis10.3
12thyroiditis10.3
13neuronitis10.3
14prostate cancer10.2
15breast cancer10.2
16leukemia10.2
17lymphoma10.2
18typhus10.2CD40LG, CD79A
19pulmonary edema10.2CD40LG, CD79A
20congenital hypogammaglobulinemia10.2CD40LG, CD79A
21calabro syndrome10.2CD40LG, CD79A
22gamma heavy chain disease10.2CD40LG, CD79A
23exanthema subitum10.2CD40LG, CD79A
24osteomalacia10.2CD40LG, CD79A
25epidermolysis bullosa simplex10.2CD40LG, CD79A
26proliferative glomerulonephritis10.2CD40LG, CD79A
27cryopyrin-associated periodic syndrome10.2CD40LG, CD79A
28acute salpingitis10.2CD40LG, CD79A
29beriberi10.2CD40LG, CD79A
30arthritis10.2
31ovarian cancer10.2
32adenoma10.2
33neuropathy10.2
34choroid plexus meningioma10.2CD40LG, CD79A
35immunotactoid glomerulopathy10.2CD40LG, CD79A
36subacute delirium10.2CD40LG, CD79A
37alpha chain disease10.2CD40LG, CD79A
38dysgammaglobulinemia10.2CD40LG, CD79A
39generalized atherosclerosis10.2CD40LG, CD79A
40central sleep apnea10.2CD40LG, CD79A
41sialadenitis10.2CD40LG, CD79A
42ureteral lymphoma10.2CD40LG, CD79A
43mixed lacrimal gland cancer10.2CD40LG, CD79A
44somatoform disorder10.2CD40LG, CD79A
45aids phobia10.2CD40LG, CD79A
46ocular hypotension10.2CD40LG, CD79A
47differentiating neuroblastoma10.2CD40LG, CD79A
48tenosynovitis10.2CD40LG, CD79A
49brucella melitensis brucellosis10.2CD40LG, CD79A
50fallopian tube carcinoma10.2CD40LG, CD79A

Graphical network of the top 20 diseases related to Congenital Toxoplasmosis:



Diseases related to congenital toxoplasmosis

Symptoms for Congenital Toxoplasmosis

About this section

Symptoms:

 51 (show all 27)
  • retinitis pigmentosa/retinal pigmentary changes
  • prematurity
  • antenatal exposure : toxoplasmosis
  • mild visual loss/impaired visual acuity
  • microcephaly
  • anophthalmos/anophthalmia/microphthalmos/microphthalmia
  • visual loss/blindness/amblyopia
  • nystagmus
  • hearing loss/hypoacusia/deafness
  • macules
  • ascitis
  • acute diarrhea
  • hepatitis/icterus/cholestasis
  • hepatomegaly/liver enlargement (excluding storage disease)
  • abnormal hepatic enzymes/transaminases
  • cardiomegaly
  • lymphadenopathy/polyadenopathies
  • dilated cerebral ventricles without hydrocephaly
  • hydrocephaly
  • intracranial/cerebral calcifications
  • hypotonia
  • seizures/epilepsy/absences/spasms/status epilepticus
  • intellectual deficit/mental/psychomotor retardation/learning disability
  • anaemia
  • thrombocytopenia/thrombopenia
  • failure to thrive/difficulties for feeding in infancy/growth delay
  • intrauterine growth retardation

HPO human phenotypes related to Congenital Toxoplasmosis:

(show all 24)
id Description Frequency HPO Source Accession
1 premature birth hallmark (90%) HP:0001622
2 abnormality of retinal pigmentation hallmark (90%) HP:0007703
3 visual impairment typical (50%) HP:0000505
4 hydrocephalus occasional (7.5%) HP:0000238
5 microcephaly occasional (7.5%) HP:0000252
6 hearing impairment occasional (7.5%) HP:0000365
7 visual impairment occasional (7.5%) HP:0000505
8 nystagmus occasional (7.5%) HP:0000639
9 hypermelanotic macule occasional (7.5%) HP:0001034
10 seizures occasional (7.5%) HP:0001250
11 muscular hypotonia occasional (7.5%) HP:0001252
12 intrauterine growth retardation occasional (7.5%) HP:0001511
13 ascites occasional (7.5%) HP:0001541
14 cardiomegaly occasional (7.5%) HP:0001640
15 thrombocytopenia occasional (7.5%) HP:0001873
16 anemia occasional (7.5%) HP:0001903
17 diarrhea occasional (7.5%) HP:0002014
18 ventriculomegaly occasional (7.5%) HP:0002119
19 hepatomegaly occasional (7.5%) HP:0002240
20 cerebral calcification occasional (7.5%) HP:0002514
21 lymphadenopathy occasional (7.5%) HP:0002716
22 elevated hepatic transaminases occasional (7.5%) HP:0002910
23 aplasia/hypoplasia affecting the eye occasional (7.5%) HP:0008056
24 cognitive impairment occasional (7.5%) HP:0100543

Drugs & Therapeutics for Congenital Toxoplasmosis

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Drugs for Congenital Toxoplasmosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
SulfadiazineapprovedPhase 4, Phase 33268-35-95215
Synonyms:
141582-64-1
2-Sulfanilamido-pyrimidine
2-Sulfanilamidopyrimidin
2-Sulfanilamidopyrimidin [German]
2-Sulfanilamidopyrimidine
2-Sulfanilylaminopyrimidine
2-Sulfapyrimidine
2-sulfanilamidopyrimidine
2-sulfanilylaminopyrimidine
35033_FLUKA
35033_RIEDEL
4-AMINO-N-2-PYRIMIDINYLBENZENESULFONAMIDE
4-Amino-N-(2-pyrimidinyl)benzenesulfonamide
4-Amino-N-2-pyrimidinyl- benzenesulfonamide
4-Amino-N-2-pyrimidinyl-benzenesulfonamide
4-amino-N-(pyrimidin-2-yl)benzenesulfonamide
4-amino-N-2-pyrimidinylbenzenesulfonamide
4-amino-N-pyrimidin-2-ylbenzenesulfonamide
5-25-10-00067 (Beilstein Handbook Reference)
68-35-9
A 306
A-306
A-306 (VAN)
AB00052095
AC-12001
AC1L1JUR
AC1Q51XM
AC1Q6W1E
AI3-01047
AKOS000119073
AR-1L4215
Adiazin
Adiazin, Adiazine, Debenal, Liquadiazine, Microsulfon, Sulfazine, Sulfolex, Sulfadiazine
Adiazine
BB_SC-0628
BPBio1_000095
BRD-K32273377-001-05-4
BRN 0235192
BSPBio_000085
BSPBio_002884
C07658
C10H10N4O2S
CAS-68-35-9
CHEBI:9328
CHEMBL439
CID5215
CRL-8131 & Sulfadiazine
Coco-Diazine
CocoDiazine
Cocodiazine
Codiazine
Cremodiazine
Cremotres
D00587
D013411
DB00359
Debenal
Deltazina
Di-Azo-Mul
Diazin
Diazolone
Diazovit
Diazyl
DivK1c_000543
EINECS 200-685-8
Eskadiazine
HMS1568E07
HMS1921A13
HMS2090P09
HMS2092I15
HMS501L05
Honey Diazine
Honey diazine
IDI1_000543
KBio1_000543
KBio2_001466
KBio2_004034
KBio2_006602
KBio3_002104
KBioGR_000743
KBioSS_001466
LS-147838
Lantrisul
Lipo-Diazine
Lipo-Levazine
Liquadiazine
MLS000069423
Metha-Meridiazine
Microsulfon
Mixture of sulfadiazine, sulfamerazine, and sulfamethazine
MolPort-000-629-738
N(1)-2-Pyrimidinylsulfanilamide
N(1)-2-Pyrimidylsulfanilamide
N(1)-2-pyrimidinylsulfanilamide
N(1)-2-pyrimidylsulfanilamide
N(sup 1)-2-Pyrimidinylsulfanilamide
N(sup1)-2-Pyrimidinylsulfanilamide
N(sup1)-2-Pyrimidylsulfanilamide
N-(2-Pyrimidinyl)sulfanilamide
 
N1-(Pyrimidin-2-yl)sulfanilamide
N1-2-pyrimidinylsulfanilamide
N1-2-pyrimidylsulfanilamide
NCGC00016305-01
NCGC00016305-02
NCGC00023291-03
NCGC00023291-04
NINDS_000543
NSC 35600
NSC117870
NSC35600
Neazine
Neotrizine
Oprea1_081078
Palatrize
Pecta-Diazine
Pecta-diazine, suspension
Piridisir
Pirimal
Prestwick0_000023
Prestwick1_000023
Prestwick2_000023
Prestwick3_000023
Prestwick_428
Pyrimal
Quadetts
Quadramoid
RP 2616
Recombinant bactericidal/permeability-increasing protein & Sulfadiazine
S. N. 112
S.N. 112
S0579
S1770_Selleck
S8626_SIGMA
SDA
SMR000059113
SPBio_001417
SPBio_002006
SPECTRUM1500546
SSD
STK317797
Sanodiazine
Sildaflo
Silvadene
Solfadiazina
Solfadiazina [DCIT]
Spectrum2_001319
Spectrum3_001362
Spectrum4_000342
Spectrum5_000992
Spectrum_000986
Spofadrizine
Sterazine
Sulfa-Triple #2
Sulfacombin
Sulfadiazene
Sulfadiazin
Sulfadiazina
Sulfadiazina [INN-Spanish]
Sulfadiazine
Sulfadiazine (JAN/USP/INN)
Sulfadiazine (TN)
Sulfadiazine [USAN:INN:JAN]
Sulfadiazine, Zinc
Sulfadiazinum
Sulfadiazinum [INN-Latin]
Sulfaloid
Sulfanilamide, N1-2-pyrimidinyl- (8CI)
Sulfanilamidopyrimidine
Sulfapirimidin
Sulfapyrimidin
Sulfapyrimidin [German]
Sulfapyrimidine
Sulfatryl
Sulfazine
Sulfolex
Sulfonamides Duplex
Sulfonsol
Sulfose
Sulphadiazine
Sulphadiazine E
TL80073596
Terfonyl
Theradiazine
Thermazene
Thi-Di-Mer
Tri-Sulfameth
Trifonamide
Triple Sulfa
Triple Sulfas
Triple Sulfoid
Trisem
Trisulfapyrimidine, oral suspension
Truozine
UNII-0N7609K889
WLN: T6N CNJ BMSWR DZ
ZINC00120319
Zinc Sulfadiazine
rBPI21 & Sulfa
sulfadiazine
2
PyrimethamineapprovedPhase 4, Phase 314658-14-04993
Synonyms:
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
46706_FLUKA
46706_RIEDEL
4753 R.P.
4753 r.p
5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE
5-(4-CHLOROPHENYL)-6-ETHYL-2,4-PYRIMIDINEDIAMINE
5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidi nediamine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
5-(4-chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
5-(p-chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-[4-Chlorophenyl]-6-ethyl-2,4-pyrimidinediamine
58-14-0
AB00052084
AC-7879
AC1L1JDI
AI3-25005
AZT + Pyrimethamine combination
Aventis Brand of Pyrimethamine
BIDD:GT0149
BIDD:PXR0173
BPBio1_000147
BRD-K88429204-001-05-4
BRN 0219864
BSPBio_000133
BSPBio_003282
BW 50-63
BW 5063
C07391
C12H13ClN4
CAS-58-14-0
CCRIS 546
CD
CHEBI:8673
CHEMBL36
CID4993
CP6
CPD000058714
CRL-8131 & Pyrimethamine
CRL-8142 & Pyrimethamine
Chloridin
Chloridine
Chloridyn
D00488
D011739
DB00205
Darachlor
Daraclor
Darapram
Daraprim
Daraprim (TN)
Daraprime
Daraprin
Diaminopyritamin
Disulone
DivK1c_000652
EINECS 200-364-2
EXR-101
Erbaprelina
Ethylpyrimidine
Fansidar
Fansidar (Pyrimethamine/Sulfadoxine)
Glaxo Wellcome Brand of Pyrimethamine
GlaxoSmithKline Brand of Pyrimethamine
HMS1568G15
HMS1920N12
HMS2092E13
HMS502A14
IDI1_000652
KBio1_000652
KBio2_001386
KBio2_003954
 
KBio2_006522
KBio3_002502
KBioGR_001007
KBioSS_001386
Khloridin
L000713
LS-238
Lactoferrin B & Pyrimethamine
Lactoferrin H & Pyrimethamine
MCB-3837
MLS000028606
MLS001148621
MLS002454446
MLS002701881
Malacid
Malocid
Malocide
Maloprim
MolPort-001-783-655
NCGC00016256-01
NCGC00016256-02
NCGC00023188-03
NCGC00023188-04
NCGC00023188-05
NCGC00023188-06
NCGC00023188-07
NCI-C01683
NCI60_002604
NCIOpen2_008313
NINDS_000652
NSC 3061
NSC-3061
NSC3061
Oxaquin
Pirimecidan
Pirimetamin
Pirimetamina
Pirimetamina [INN-Spanish]
Pirimetamina [Spanish]
Prestwick0_000037
Prestwick1_000037
Prestwick2_000037
Prestwick3_000037
Prestwick_504
Primethamine
Pyremethamine
Pyrimethamin
Pyrimethamine (JAN/USP/INN)
Pyrimethamine (Pyr)
Pyrimethamine Hcl
Pyrimethamine Hydrochloride
Pyrimethamine [USAN:INN:BAN:JAN]
Pyrimethaminum
Pyrimethaminum [INN-Latin]
RP 4753
S2006_Selleck
SAM002554921
SMR000058714
SPBio_000672
SPBio_002054
SPECTRUM1500520
Spectrum2_000886
Spectrum3_001701
Spectrum4_000494
Spectrum5_001447
Spectrum_000906
TCMDC-123831
TCMDC-125860
Tindurin
Tindurine
Tinduring
UNII-Z3614QOX8W
WLN: T6N CNJ BZ DZ ER DG& F2
WR 2978
Wellcome Brand of Pyrimethamine
ZINC00057464
m alocid
nchembio.215-comp13
nchembio.87-comp22
pyrimethamine
3
leucovorinapprovedPhase 49521492-18-854575
Synonyms:
(6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid
(6S)-Folinic acid
(6S)-Leucovorin
(S)-Leucovorin
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinic acid
Folinic acid calcium salt
Folinic acid calcium salt USP27
Folinic acid-SF
Fusilev
 
L-Folinic acid
L-leucovorin
Leucal
Leucovorin
Leucovorin Calcium
Leucovorin calcium
Leucovorin folinic acid
Leucovorin sodium
Leukovorin
Levofolene
Levofolinic acid
Levoleucovorin
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
Wellcovorin
4
Folic Acidapproved, nutraceuticalPhase 4, Phase 3292459-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic Acid
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
 
Folsaeure
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
5SpiramycinPhase 4, Phase 34
6AntimalarialsPhase 4, Phase 31058
7Protective AgentsPhase 45651
8Anti-Infective AgentsPhase 4, Phase 317220
9MicronutrientsPhase 43901
10Vitamin B ComplexPhase 4, Phase 32847
11Trace ElementsPhase 43900
12VitaminsPhase 43857
13LevoleucovorinPhase 4, Phase 3676
14Calcium, DietaryPhase 44678
15Antiprotozoal AgentsPhase 4, Phase 31730
16Antiparasitic AgentsPhase 4, Phase 31854
17Folic Acid AntagonistsPhase 4, Phase 31643
18Anti-Bacterial AgentsPhase 4, Phase 39140
19Vitamin B9NutraceuticalPhase 4, Phase 32924
20Folinic AcidNutraceuticalPhase 4, Phase 32604
21FolateNutraceuticalPhase 4, Phase 32924

Interventional clinical trials:

idNameStatusNCT IDPhase
1Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital ToxoplasmosisRecruitingNCT00004317Phase 4
2Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital ToxoplasmosisRecruitingNCT01202500Phase 3
3Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During PregnancyRecruitingNCT01189448Phase 3

Search NIH Clinical Center for Congenital Toxoplasmosis


Cochrane evidence based reviews: toxoplasmosis, congenital

Genetic Tests for Congenital Toxoplasmosis

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Anatomical Context for Congenital Toxoplasmosis

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MalaCards organs/tissues related to Congenital Toxoplasmosis:

33
Breast, Liver, Eye, Endothelial, B cells, Brain, Lung

Animal Models for Congenital Toxoplasmosis or affiliated genes

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Publications for Congenital Toxoplasmosis

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Articles related to Congenital Toxoplasmosis:

(show top 50)    (show all 533)
idTitleAuthorsYear
1
N-myc downstream-regulated gene 2 (NDRG2) suppresses the epithelial-mesenchymal transition (EMT) in breast cancer cells via STAT3/Snail signaling. (25153349)
2014
2
Optimal and variant metal-ion routes in DNA polymerase I^'s conformational pathways. (24511902)
2014
3
Treatment of symptomatic carotid stenosis: carotid stent placement versus endarterectomy. (23873312)
2013
4
Congenital cholesteatoma in identical twins. (23217274)
2013
5
Body mass index and the development of amiodarone-induced thyrotoxicosis in adults with congenital heart disease--a cohort study. (22386642)
2013
6
MEFV gene mutations and their clinical significance in Korean patients with adult-onset Still's disease. (24064016)
2013
7
Expressions of EZH2 and RUNX3 in renal cell carcinoma and their clinical significance]. (23294722)
2013
8
KLF10, transforming growth factor-I^-inducible early gene 1, acts as a tumor suppressor. (22349513)
2012
9
miR-21 is targeted by omega-3 polyunsaturated fatty acid to regulate breast tumor CSF-1 expression. (22678116)
2012
10
Umbilical artery chemokine CCL16 is associated with preterm preeclampsia and fetal growth restriction. (22857868)
2012
11
Novel chromosomal translocation (17;22)(q12;q12) in a case of myelodisplastic syndrome characterized with signs of hemolytic anemia at presentation. (22138479)
2012
12
B cell depletion therapy for new-onset opsoclonus-myoclonus. (20063398)
2010
13
SUMOylation of human peroxisome proliferator-activated receptor alpha inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR. (19955185)
2010
14
The anatomy of extended limbic pathways in Asperger syndrome: a preliminary diffusion tensor imaging tractography study. (19446642)
2009
15
On the nosology and pathogenesis of Wolf-Hirschhorn syndrome: genotype-phenotype correlation analysis of 80 patients and literature review. (18932124)
2008
16
Use of multicellular tumor spheroids to dissect endothelial cell-tumor cell interactions: a role for T-cadherin in tumor angiogenesis. (17765896)
2007
17
Pulmonary alveolar proteinosis--is host defense awry? (17287475)
2007
18
Galectin-8 and galectin-9 are novel substrates for thrombin. (16868247)
2006
19
Two way communication between neutrophils and dendritic cells. (16750420)
2006
20
Inhibitory anti-FLT3 antibodies are capable of mediating antibody-dependent cell-mediated cytotoxicity and reducing engraftment of acute myelogenous leukemia blasts in nonobese diabetic/severe combined immunodeficient mice. (15735040)
2005
21
Regulation of cyclin expression and cell cycle progression in breast epithelial cells by the helix-loop-helix protein Id1. (15489884)
2005
22
CXCR3 polymorphisms associated with risk of asthma. (16043121)
2005
23
Gene interactions and stroke risk in children with sickle cell anemia. (14615367)
2004
24
Migration and differentiation of Langerhans cell precursors. (15679124)
2004
25
Expression of GLUT-1 glucose transfer, cellular proliferation activity and grade of tumor correlate with [F-18]-fluorodeoxyglucose uptake by positron emission tomography in epithelial tumors of the ovary. (15027127)
2004
26
Plasma leptin levels in patients with primary biliary cirrhosis and their relationship with degree of fibrosis]. (14733878)
2004
27
Possible association between -G308A tumour necrosis factor-alpha gene polymorphism and major depressive disorder in the Korean population. (12960751)
2003
28
Mitral and aortic valve thickening associated with galactosialidosis: echocardiographic features of a lysosomal storage disease. (14536008)
2003
29
Parathyroid hormone-related protein regulates the growth of orthotopic human lung tumors in athymic mice. (11745216)
2001
30
Joint effect of G1691A factor V point mutation and factor VII Arg/Gln(353) gene polymorphism on the risk of premature coronary artery disease. (11334615)
2001
31
Treatment of fluid overload and kidney failure with periotoneal dialysis after heart surgery]. (11227359)
2000
32
Molecular cloning of a cDNA encoding alpha-glucosidase in the digestive gland of the shrimp, Litopenaeus vannamei. (10961350)
2000
33
Usefulness of selected circulating biochemical markers in diagnosis and monitoring of endometriosis]. (10390920)
1999
34
Impairment of the blood-brain barrier: a potential surrogate delineating the determinants of cerebral bleeding caused by fibrinolytic drugs. (10474793)
1999
35
Severe laryngomalacia: surgical indications and results. (9443320)
1997
36
Levels of serum 1,25(OH)2D in patients with pre-dialysis chronic renal failure. (8933671)
1996
37
Effects of intraperitoneal cyclooxygenase inhibition on inflammatory mediators in dialysate and peritoneal membrane characteristics during peritonitis in continuous ambulatory peritoneal dialysis. (7636393)
1995
38
Local synthesis of apolipoprotein J in the eye. (7615015)
1995
39
Co-existent renal replacement lipomatosis and pyelitis glandularis. (7959988)
1994
40
Targeting of the Gi2 alpha gene in ES cells with replacement and insertion vectors. (8450507)
1993
41
Evidence against depletion of the growth hormone (GH)-releasable pool in human primary hypothyroidism: studies with GH-releasing hormone, pyridostigmine, and arginine. (8103770)
1993
42
Effects of tolerance induction on early cell cycle progression by Th1 clones. (1374289)
1992
43
Arterial thrombosis and protein S deficiency. (1447661)
1992
44
Activation of human monocytes by granulocyte-macrophage colony-stimulating factor: increased urokinase-type plasminogen activator activity. (1899623)
1991
45
Glucocorticoids inhibit cytokine-mediated eosinophil survival. (1940348)
1991
46
Molecular operations of the sodium-calcium exchanger revealed by conformation currents. (2000135)
1991
47
A possible direct precursor of thyrotropin-releasing hormone, pGlu-His-Pro-Gly, stimulates prolactin secretion in anorexia nervosa. (2115046)
1990
48
Olfactory neuroblastoma: report of a case and review of the literature. (2651629)
1989
49
Nephrogenic adenoma. Reports of two cases. (2922583)
1989
50
Epithelioid sarcoma: an analysis of 22 cases indicating the prognostic significance of vascular invasion and regional lymph node metastasis. (639005)
1978

Variations for Congenital Toxoplasmosis

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Expression for genes affiliated with Congenital Toxoplasmosis

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Search GEO for disease gene expression data for Congenital Toxoplasmosis.

Pathways for genes affiliated with Congenital Toxoplasmosis

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Pathways related to Congenital Toxoplasmosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7CD40LG, CD79A
29.6CD40LG, COL2A1

GO Terms for genes affiliated with Congenital Toxoplasmosis

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Sources for Congenital Toxoplasmosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet