MCID: CNG021
MIFTS: 47

Congenital Toxoplasmosis malady

Categories: Rare diseases, Fetal diseases, Neuronal diseases, Infectious diseases

Aliases & Classifications for Congenital Toxoplasmosis

About this section
Sources:
10Disease Ontology, 45NIH Rare Diseases, 12DISEASES, 51Orphanet, 47Novoseek, 36MeSH, 65UMLS, 27ICD10, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Congenital Toxoplasmosis:

Name: Congenital Toxoplasmosis 10 45 12 51
Toxoplasmosis, Congenital 36 65
Toxoplasma Embryofetopathy 51
 
Toxoplasmosis Congenital 47
Toxoplasmosis - Congen. 10
Toxoplasma Embryopathy 51

Characteristics:

Orphanet epidemiological data:

51
congenital toxoplasmosis:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe),1-5/10000 (United States); Age of onset: Adolescent,Adult,Antenatal,Childhood,Infancy,Neonatal

Classifications:



External Ids:

Disease Ontology10 DOID:13336
ICD1027 P37.1
MeSH36 D014125
NCIt42 C50503
Orphanet51 858
ICD10 via Orphanet28 P37.1
MESH via Orphanet37 D014125
UMLS via Orphanet66 C0040560
UMLS65 C0040560

Summaries for Congenital Toxoplasmosis

About this section
Disease Ontology:10 A toxoplasmosis that involves a reactivated infection of the mother transmitted to the fetus during pregnancy. Spontaneous abortion and stillbirth may occur.

MalaCards based summary: Congenital Toxoplasmosis, also known as toxoplasmosis, congenital, is related to toxoplasmosis and typhus, and has symptoms including premature birth, abnormality of retinal pigmentation and visual impairment. An important gene associated with Congenital Toxoplasmosis is CD40LG (CD40 Ligand), and among its related pathways are Primary immunodeficiency and T Cell Co-Signaling Pathway: Ligand-Receptor Interactions. Affiliated tissues include liver, heart and b cells.

Related Diseases for Congenital Toxoplasmosis

About this section

Diseases in the Toxoplasmosis family:

congenital toxoplasmosis

Diseases related to Congenital Toxoplasmosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 174)
idRelated DiseaseScoreTop Affiliating Genes
1toxoplasmosis11.4
2typhus10.3CD40LG, CD79A
3pulmonary edema10.3CD40LG, CD79A
4congenital hypogammaglobulinemia10.3CD40LG, CD79A
5calabro syndrome10.3CD40LG, CD79A
6gamma heavy chain disease10.3CD40LG, CD79A
7exanthema subitum10.3CD40LG, CD79A
8osteomalacia10.3CD40LG, CD79A
9epidermolysis bullosa simplex10.3CD40LG, CD79A
10proliferative glomerulonephritis10.3CD40LG, CD79A
11cryopyrin-associated periodic syndrome10.3CD40LG, CD79A
12acute salpingitis10.3CD40LG, CD79A
13beriberi10.3CD40LG, CD79A
14cystitis10.3CD40LG, CD79A
15purpura10.3CD40LG, CD79A
16choroid plexus meningioma10.3CD40LG, CD79A
17immunotactoid glomerulopathy10.2CD40LG, CD79A
18subacute delirium10.2CD40LG, CD79A
19alpha chain disease10.2CD40LG, CD79A
20dysgammaglobulinemia10.2CD40LG, CD79A
21generalized atherosclerosis10.2CD40LG, CD79A
22central sleep apnea10.2CD40LG, CD79A
23sialadenitis10.2CD40LG, CD79A
24ureteral lymphoma10.2CD40LG, CD79A
25mixed lacrimal gland cancer10.2CD40LG, CD79A
26somatoform disorder10.2CD40LG, CD79A
27aids phobia10.2CD40LG, CD79A
28ocular hypotension10.2CD40LG, CD79A
29differentiating neuroblastoma10.2CD40LG, CD79A
30tenosynovitis10.2CD40LG, CD79A
31brucella melitensis brucellosis10.2CD40LG, CD79A
32fallopian tube carcinoma10.2CD40LG, CD79A
33maxillary sinusitis10.2CD40LG, CD79A
34plasma protein metabolism disease10.2CD40LG, CD79A
35peripheral nervous system disease10.2CD40LG, CD79A
36primary systemic mycosis10.2CD40LG, CD79A
37impaired renal function disease10.2CD40LG, CD79A
38calcific tendinitis10.2CD40LG, CD79A
39skin granular cell tumor10.2CD40LG, CD79A
40spinocerebellar ataxia, autosomal recessive 1010.2CD40LG, CD79A
41weill-marchesani syndrome10.2CD40LG, CD79A
42late congenital syphilis10.2CD40LG, CD79A
43pityriasis rosea10.2CD40LG, CD79A
44indolent myeloma10.2CD40LG, CD79A
45isodicentric 1510.2CD40LG, CD79A
46craniofacioskeletal syndrome10.2CD40LG, CD79A
47cd40 deficiency10.2CD40LG, CD79A
48acute necrotizing encephalitis10.2CD40LG, CD79A
49bejel10.2CD40LG, CD79A
50subacute glomerulonephritis10.2CD40LG, CD79A

Graphical network of the top 20 diseases related to Congenital Toxoplasmosis:



Diseases related to congenital toxoplasmosis

Symptoms for Congenital Toxoplasmosis

About this section

Symptoms:

 51 (show all 27)
  • retinitis pigmentosa/retinal pigmentary changes
  • prematurity
  • antenatal exposure : toxoplasmosis
  • mild visual loss/impaired visual acuity
  • microcephaly
  • anophthalmos/anophthalmia/microphthalmos/microphthalmia
  • visual loss/blindness/amblyopia
  • nystagmus
  • hearing loss/hypoacusia/deafness
  • macules
  • ascitis
  • acute diarrhea
  • hepatitis/icterus/cholestasis
  • hepatomegaly/liver enlargement (excluding storage disease)
  • abnormal hepatic enzymes/transaminases
  • cardiomegaly
  • lymphadenopathy/polyadenopathies
  • dilated cerebral ventricles without hydrocephaly
  • hydrocephaly
  • intracranial/cerebral calcifications
  • hypotonia
  • seizures/epilepsy/absences/spasms/status epilepticus
  • intellectual deficit/mental/psychomotor retardation/learning disability
  • anaemia
  • thrombocytopenia/thrombopenia
  • failure to thrive/difficulties for feeding in infancy/growth delay
  • intrauterine growth retardation

HPO human phenotypes related to Congenital Toxoplasmosis:

(show all 24)
id Description Frequency HPO Source Accession
1 premature birth hallmark (90%) HP:0001622
2 abnormality of retinal pigmentation hallmark (90%) HP:0007703
3 visual impairment typical (50%) HP:0000505
4 hydrocephalus occasional (7.5%) HP:0000238
5 microcephaly occasional (7.5%) HP:0000252
6 hearing impairment occasional (7.5%) HP:0000365
7 visual impairment occasional (7.5%) HP:0000505
8 nystagmus occasional (7.5%) HP:0000639
9 hypermelanotic macule occasional (7.5%) HP:0001034
10 seizures occasional (7.5%) HP:0001250
11 muscular hypotonia occasional (7.5%) HP:0001252
12 intrauterine growth retardation occasional (7.5%) HP:0001511
13 ascites occasional (7.5%) HP:0001541
14 cardiomegaly occasional (7.5%) HP:0001640
15 thrombocytopenia occasional (7.5%) HP:0001873
16 anemia occasional (7.5%) HP:0001903
17 diarrhea occasional (7.5%) HP:0002014
18 ventriculomegaly occasional (7.5%) HP:0002119
19 hepatomegaly occasional (7.5%) HP:0002240
20 cerebral calcification occasional (7.5%) HP:0002514
21 lymphadenopathy occasional (7.5%) HP:0002716
22 elevated hepatic transaminases occasional (7.5%) HP:0002910
23 aplasia/hypoplasia affecting the eye occasional (7.5%) HP:0008056
24 cognitive impairment occasional (7.5%) HP:0100543

Drugs & Therapeutics for Congenital Toxoplasmosis

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Drugs for Congenital Toxoplasmosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
SulfadiazineapprovedPhase 4, Phase 33268-35-95215
Synonyms:
141582-64-1
2-Sulfanilamido-pyrimidine
2-Sulfanilamidopyrimidin
2-Sulfanilamidopyrimidin [German]
2-Sulfanilamidopyrimidine
2-Sulfanilylaminopyrimidine
2-Sulfapyrimidine
2-sulfanilamidopyrimidine
2-sulfanilylaminopyrimidine
35033_FLUKA
35033_RIEDEL
4-AMINO-N-2-PYRIMIDINYLBENZENESULFONAMIDE
4-Amino-N-(2-pyrimidinyl)benzenesulfonamide
4-Amino-N-2-pyrimidinyl- benzenesulfonamide
4-Amino-N-2-pyrimidinyl-benzenesulfonamide
4-amino-N-(pyrimidin-2-yl)benzenesulfonamide
4-amino-N-2-pyrimidinylbenzenesulfonamide
4-amino-N-pyrimidin-2-ylbenzenesulfonamide
5-25-10-00067 (Beilstein Handbook Reference)
68-35-9
A 306
A-306
A-306 (VAN)
AB00052095
AC-12001
AC1L1JUR
AC1Q51XM
AC1Q6W1E
AI3-01047
AKOS000119073
AR-1L4215
Adiazin
Adiazin, Adiazine, Debenal, Liquadiazine, Microsulfon, Sulfazine, Sulfolex, Sulfadiazine
Adiazine
BB_SC-0628
BPBio1_000095
BRD-K32273377-001-05-4
BRN 0235192
BSPBio_000085
BSPBio_002884
C07658
C10H10N4O2S
CAS-68-35-9
CHEBI:9328
CHEMBL439
CID5215
CRL-8131 & Sulfadiazine
Coco-Diazine
CocoDiazine
Cocodiazine
Codiazine
Cremodiazine
Cremotres
D00587
D013411
DB00359
Debenal
Deltazina
Di-Azo-Mul
Diazin
Diazolone
Diazovit
Diazyl
DivK1c_000543
EINECS 200-685-8
Eskadiazine
HMS1568E07
HMS1921A13
HMS2090P09
HMS2092I15
HMS501L05
Honey Diazine
Honey diazine
IDI1_000543
KBio1_000543
KBio2_001466
KBio2_004034
KBio2_006602
KBio3_002104
KBioGR_000743
KBioSS_001466
LS-147838
Lantrisul
Lipo-Diazine
Lipo-Levazine
Liquadiazine
MLS000069423
Metha-Meridiazine
Microsulfon
Mixture of sulfadiazine, sulfamerazine, and sulfamethazine
MolPort-000-629-738
N(1)-2-Pyrimidinylsulfanilamide
N(1)-2-Pyrimidylsulfanilamide
N(1)-2-pyrimidinylsulfanilamide
N(1)-2-pyrimidylsulfanilamide
N(sup 1)-2-Pyrimidinylsulfanilamide
N(sup1)-2-Pyrimidinylsulfanilamide
N(sup1)-2-Pyrimidylsulfanilamide
N-(2-Pyrimidinyl)sulfanilamide
 
N1-(Pyrimidin-2-yl)sulfanilamide
N1-2-pyrimidinylsulfanilamide
N1-2-pyrimidylsulfanilamide
NCGC00016305-01
NCGC00016305-02
NCGC00023291-03
NCGC00023291-04
NINDS_000543
NSC 35600
NSC117870
NSC35600
Neazine
Neotrizine
Oprea1_081078
Palatrize
Pecta-Diazine
Pecta-diazine, suspension
Piridisir
Pirimal
Prestwick0_000023
Prestwick1_000023
Prestwick2_000023
Prestwick3_000023
Prestwick_428
Pyrimal
Quadetts
Quadramoid
RP 2616
Recombinant bactericidal/permeability-increasing protein & Sulfadiazine
S. N. 112
S.N. 112
S0579
S1770_Selleck
S8626_SIGMA
SDA
SMR000059113
SPBio_001417
SPBio_002006
SPECTRUM1500546
SSD
STK317797
Sanodiazine
Sildaflo
Silvadene
Solfadiazina
Solfadiazina [DCIT]
Spectrum2_001319
Spectrum3_001362
Spectrum4_000342
Spectrum5_000992
Spectrum_000986
Spofadrizine
Sterazine
Sulfa-Triple #2
Sulfacombin
Sulfadiazene
Sulfadiazin
Sulfadiazina
Sulfadiazina [INN-Spanish]
Sulfadiazine
Sulfadiazine (JAN/USP/INN)
Sulfadiazine (TN)
Sulfadiazine [USAN:INN:JAN]
Sulfadiazine, Zinc
Sulfadiazinum
Sulfadiazinum [INN-Latin]
Sulfaloid
Sulfanilamide, N1-2-pyrimidinyl- (8CI)
Sulfanilamidopyrimidine
Sulfapirimidin
Sulfapyrimidin
Sulfapyrimidin [German]
Sulfapyrimidine
Sulfatryl
Sulfazine
Sulfolex
Sulfonamides Duplex
Sulfonsol
Sulfose
Sulphadiazine
Sulphadiazine E
TL80073596
Terfonyl
Theradiazine
Thermazene
Thi-Di-Mer
Tri-Sulfameth
Trifonamide
Triple Sulfa
Triple Sulfas
Triple Sulfoid
Trisem
Trisulfapyrimidine, oral suspension
Truozine
UNII-0N7609K889
WLN: T6N CNJ BMSWR DZ
ZINC00120319
Zinc Sulfadiazine
rBPI21 & Sulfa
sulfadiazine
2
PyrimethamineapprovedPhase 4, Phase 314658-14-04993
Synonyms:
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
46706_FLUKA
46706_RIEDEL
4753 R.P.
4753 r.p
5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE
5-(4-CHLOROPHENYL)-6-ETHYL-2,4-PYRIMIDINEDIAMINE
5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidi nediamine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
5-(4-chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
5-(p-chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-[4-Chlorophenyl]-6-ethyl-2,4-pyrimidinediamine
58-14-0
AB00052084
AC-7879
AC1L1JDI
AI3-25005
AZT + Pyrimethamine combination
Aventis Brand of Pyrimethamine
BIDD:GT0149
BIDD:PXR0173
BPBio1_000147
BRD-K88429204-001-05-4
BRN 0219864
BSPBio_000133
BSPBio_003282
BW 50-63
BW 5063
C07391
C12H13ClN4
CAS-58-14-0
CCRIS 546
CD
CHEBI:8673
CHEMBL36
CID4993
CP6
CPD000058714
CRL-8131 & Pyrimethamine
CRL-8142 & Pyrimethamine
Chloridin
Chloridine
Chloridyn
D00488
D011739
DB00205
Darachlor
Daraclor
Darapram
Daraprim
Daraprim (TN)
Daraprime
Daraprin
Diaminopyritamin
Disulone
DivK1c_000652
EINECS 200-364-2
EXR-101
Erbaprelina
Ethylpyrimidine
Fansidar
Fansidar (Pyrimethamine/Sulfadoxine)
Glaxo Wellcome Brand of Pyrimethamine
GlaxoSmithKline Brand of Pyrimethamine
HMS1568G15
HMS1920N12
HMS2092E13
HMS502A14
IDI1_000652
KBio1_000652
KBio2_001386
KBio2_003954
 
KBio2_006522
KBio3_002502
KBioGR_001007
KBioSS_001386
Khloridin
L000713
LS-238
Lactoferrin B & Pyrimethamine
Lactoferrin H & Pyrimethamine
MCB-3837
MLS000028606
MLS001148621
MLS002454446
MLS002701881
Malacid
Malocid
Malocide
Maloprim
MolPort-001-783-655
NCGC00016256-01
NCGC00016256-02
NCGC00023188-03
NCGC00023188-04
NCGC00023188-05
NCGC00023188-06
NCGC00023188-07
NCI-C01683
NCI60_002604
NCIOpen2_008313
NINDS_000652
NSC 3061
NSC-3061
NSC3061
Oxaquin
Pirimecidan
Pirimetamin
Pirimetamina
Pirimetamina [INN-Spanish]
Pirimetamina [Spanish]
Prestwick0_000037
Prestwick1_000037
Prestwick2_000037
Prestwick3_000037
Prestwick_504
Primethamine
Pyremethamine
Pyrimethamin
Pyrimethamine (JAN/USP/INN)
Pyrimethamine (Pyr)
Pyrimethamine Hcl
Pyrimethamine Hydrochloride
Pyrimethamine [USAN:INN:BAN:JAN]
Pyrimethaminum
Pyrimethaminum [INN-Latin]
RP 4753
S2006_Selleck
SAM002554921
SMR000058714
SPBio_000672
SPBio_002054
SPECTRUM1500520
Spectrum2_000886
Spectrum3_001701
Spectrum4_000494
Spectrum5_001447
Spectrum_000906
TCMDC-123831
TCMDC-125860
Tindurin
Tindurine
Tinduring
UNII-Z3614QOX8W
WLN: T6N CNJ BZ DZ ER DG& F2
WR 2978
Wellcome Brand of Pyrimethamine
ZINC00057464
m alocid
nchembio.215-comp13
nchembio.87-comp22
pyrimethamine
3
leucovorinapprovedPhase 49521492-18-854575
Synonyms:
(6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid
(6S)-Folinic acid
(6S)-Leucovorin
(S)-Leucovorin
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinic acid
Folinic acid calcium salt
Folinic acid calcium salt USP27
Folinic acid-SF
Fusilev
 
L-Folinic acid
L-leucovorin
Leucal
Leucovorin
Leucovorin Calcium
Leucovorin calcium
Leucovorin folinic acid
Leucovorin sodium
Leukovorin
Levofolene
Levofolinic acid
Levoleucovorin
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
Wellcovorin
4
Folic Acidapproved, nutraceuticalPhase 4, Phase 3292459-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic Acid
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
 
Folsaeure
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
5SpiramycinPhase 4, Phase 34
6AntimalarialsPhase 4, Phase 31058
7Protective AgentsPhase 45651
8Anti-Infective AgentsPhase 4, Phase 317220
9MicronutrientsPhase 43901
10Vitamin B ComplexPhase 4, Phase 32847
11Trace ElementsPhase 43900
12VitaminsPhase 43857
13LevoleucovorinPhase 4, Phase 3676
14Calcium, DietaryPhase 44678
15Antiprotozoal AgentsPhase 4, Phase 31730
16Antiparasitic AgentsPhase 4, Phase 31854
17Folic Acid AntagonistsPhase 4, Phase 31643
18Anti-Bacterial AgentsPhase 4, Phase 39140
19Vitamin B9NutraceuticalPhase 4, Phase 32924
20Folinic AcidNutraceuticalPhase 4, Phase 32604
21FolateNutraceuticalPhase 4, Phase 32924

Interventional clinical trials:

idNameStatusNCT IDPhase
1Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital ToxoplasmosisRecruitingNCT00004317Phase 4
2Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital ToxoplasmosisRecruitingNCT01202500Phase 3
3Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During PregnancyRecruitingNCT01189448Phase 3

Search NIH Clinical Center for Congenital Toxoplasmosis


Cochrane evidence based reviews: toxoplasmosis, congenital

Genetic Tests for Congenital Toxoplasmosis

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Anatomical Context for Congenital Toxoplasmosis

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MalaCards organs/tissues related to Congenital Toxoplasmosis:

33
Liver, Heart, B cells, Testes, Brain, Pituitary, Thyroid

Animal Models for Congenital Toxoplasmosis or affiliated genes

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Publications for Congenital Toxoplasmosis

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Articles related to Congenital Toxoplasmosis:

(show top 50)    (show all 548)
idTitleAuthorsYear
1
Prognosis of Fetal Parenchymal Cerebral Lesions without Ventriculomegaly in Congenital Toxoplasmosis Infection. (27093552)
2016
2
Mesial Temporal Lobe Epilepsy in Congenital Toxoplasmosis: A Case Report. (26157672)
2015
3
Incidence of congenital toxoplasmosis among infants born to HIV-coinfected mothers: case series and literature review. (25017666)
2014
4
The global burden of congenital toxoplasmosis: a systematic review. (23825877)
2013
5
Congenital toxoplasmosis. (23987732)
2013
6
A dedicated surveillance network for congenital toxoplasmosis in Greece, 2006-2009: assessment of the results. (23173875)
2012
7
Toxoplasma gondii antibody profile in HIV-1-infected and uninfected pregnant women and the impact on congenital toxoplasmosis diagnosis in Rio de Janeiro, Brazil. (22552460)
2012
8
Spinal Cord Lesions in Congenital Toxoplasmosis Demonstrated with Neuroimaging, Including Their Successful Treatment in an Adult. (23487348)
2012
9
Congenital toxoplasmosis--a report on the Danish neonatal screening programme 1999-2007. (20585987)
2010
10
Congenital toxoplasmosis from a chronically infected woman with reactivation of retinochoroiditis during pregnancy. (19918624)
2010
11
In utero and at birth diagnosis of congenital toxoplasmosis: use of likelihood ratios for clinical management. (19952858)
2010
12
Clinical relevance of placenta examination for the diagnosis of congenital toxoplasmosis. (19858771)
2010
13
Survey of European programmes for the epidemiological surveillance of congenital toxoplasmosis. (18445459)
2008
14
Hearing loss in congenital toxoplasmosis detected by newborn screening. (18392497)
2008
15
Genetic and epigenetic factors at COL2A1 and ABCA4 influence clinical outcome in congenital toxoplasmosis. (18523590)
2008
16
Disease burden of congenital toxoplasmosis. (17479945)
2007
17
Congenital toxoplasmosis: late pregnancy infections detected by neonatal screening and maternal serological testing at delivery. (17937738)
2007
18
Risk factors for Toxoplasma gondii infection in mothers of infants with congenital toxoplasmosis: implications for prenatal management and screening. (16458668)
2006
19
Globe calcification in congenital toxoplasmosis. (16816517)
2006
20
Congenital toxoplasmosis complicated with central diabetes insipidus in the first week of life. (16492446)
2006
21
Cord blood screening for congenital toxoplasmosis in northwestern Switzerland, 1982-1999. (16462288)
2006
22
Prenatal diagnosis of congenital toxoplasmosis: is there a chance for the pregnancies in settings without surveillance programs? (16260894)
2005
23
Association between congenital toxoplasmosis and preterm birth, low birthweight and small for gestational age birth. (15663394)
2005
24
Prediction of congenital toxoplasmosis by polymerase chain reaction analysis of amniotic fluid. (15842278)
2005
25
Sulfadiazine and pyrimethamine in the postnatal treatment of congenital toxoplasmosis: what are the options? (15482110)
2003
26
Evaluation of a commercial IgG/IgM Western blot assay for early postnatal diagnosis of congenital toxoplasmosis. (12649715)
2003
27
Vaccination with Toxoplasma gondii SAG-1 protein is protective against congenital toxoplasmosis in BALB/c mice but not in CBA/J mice. (14573684)
2003
28
Prenatal diagnosis of congenital toxoplasmosis. (12454967)
2002
29
Congenital toxoplasmosis in Israel: to screen or not to screen. (11875985)
2002
30
Preconception seroconversion and maternal seronegativity at delivery do not rule out the risk of congenital toxoplasmosis. (11874899)
2002
31
Serological rebound in congenital toxoplasmosis: long-term follow-up of 133 children. (11585075)
2001
32
Strategy for diagnosis of congenital toxoplasmosis: evaluation of methods comparing mothers and newborns and standard methods for postnatal detection of immunoglobulin G, M, and A antibodies. (11376068)
2001
33
Ecological comparison of the risks of mother-to-child transmission and clinical manifestations of congenital toxoplasmosis according to prenatal treatment protocol. (11561963)
2001
34
Diagnostic testing for congenital toxoplasmosis. (11176568)
2001
35
Congenital toxoplasmosis, later relapses and treatment. (10419236)
1999
36
Congenital toxoplasmosis: efficacy of maternal treatment with spiramycin alone. (9602252)
1998
37
Prevention of congenital toxoplasmosis in Szeged, Hungary. (9169181)
1997
38
Congenital toxoplasmosis: specific IgM in fetal blood, cord blood and in the newborn. (8881363)
1996
39
Evaluation of the possibilities for preventing congenital toxoplasmosis. (8155214)
1994
40
Comparative value of polymerase chain reaction and conventional biological tests for the prenatal diagnosis of congenital toxoplasmosis. (1485688)
1992
41
Rat model of congenital toxoplasmosis. (1879945)
1991
42
Hypothalamo-pituitary dysfunction in congenital toxoplasmosis. (2792124)
1989
43
Congenital toxoplasmosis in Abyssinian cats. (2773276)
1989
44
Congenital toxoplasmosis: epidemiologic features and control. (3756692)
1986
45
Oral self-mutilation in a child with congenital toxoplasmosis: a clinical report. (6592553)
1984
46
Congenital toxoplasmosis associated with acquired oculomotor nerve (CN III) palsy. (7175624)
1982
47
In vitro lymphocyte stimulation with specific antigen in congenital toxoplasmosis. (7031854)
1981
48
Toxoplasmosis and pregnancy: the prevention of congenital toxoplasmosis. (7333697)
1981
49
Hydrops fetales and congenital toxoplasmosis. Value of direct immunofluorescence test. (337198)
1978
50
An estimation of the incidence of congenital toxoplasmosis in SALo Paulo city, Brasil. (951563)
1976

Variations for Congenital Toxoplasmosis

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Expression for genes affiliated with Congenital Toxoplasmosis

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Search GEO for disease gene expression data for Congenital Toxoplasmosis.

Pathways for genes affiliated with Congenital Toxoplasmosis

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Pathways related to Congenital Toxoplasmosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7CD40LG, CD79A
29.6CD40LG, COL2A1

GO Terms for genes affiliated with Congenital Toxoplasmosis

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Sources for Congenital Toxoplasmosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet