MCID: CNG021
MIFTS: 46

Congenital Toxoplasmosis malady

Categories: Rare diseases, Fetal diseases, Neuronal diseases, Infectious diseases

Aliases & Classifications for Congenital Toxoplasmosis

About this section
Sources:
11Disease Ontology, 13DISEASES, 29ICD10, 30ICD10 via Orphanet, 38MeSH, 39MESH via Orphanet, 44NCIt, 47NIH Rare Diseases, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Congenital Toxoplasmosis:

Name: Congenital Toxoplasmosis 11 47 53 13
Toxoplasmosis, Congenital 38 67
Toxoplasma Embryofetopathy 53
 
Toxoplasmosis Congenital 49
Toxoplasmosis - Congen. 11
Toxoplasma Embryopathy 53

Characteristics:

Orphanet epidemiological data:

53
congenital toxoplasmosis:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe),1-5/10000 (United States); Age of onset: Adolescent,Adult,Antenatal,Childhood,Infancy,Neonatal

Classifications:



External Ids:

Disease Ontology11 DOID:13336
ICD1029 P37.1
MeSH38 D014125
NCIt44 C50503
Orphanet53 ORPHA858
ICD10 via Orphanet30 P37.1
MESH via Orphanet39 D014125
UMLS via Orphanet68 C0040560

Summaries for Congenital Toxoplasmosis

About this section
Disease Ontology:11 A toxoplasmosis that involves a reactivated infection of the mother transmitted to the fetus during pregnancy. Spontaneous abortion and stillbirth may occur.

MalaCards based summary: Congenital Toxoplasmosis, also known as toxoplasmosis, congenital, is related to toxoplasmosis and calcific tendinitis, and has symptoms including premature birth, abnormality of retinal pigmentation and visual impairment. An important gene associated with Congenital Toxoplasmosis is CD40LG (CD40 Ligand), and among its related pathways are Primary immunodeficiency and T Cell Co-Signaling Pathway: Ligand-Receptor Interactions. Affiliated tissues include testes, eye and brain.

Related Diseases for Congenital Toxoplasmosis

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Diseases in the Toxoplasmosis family:

congenital toxoplasmosis

Diseases related to Congenital Toxoplasmosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 184)
idRelated DiseaseScoreTop Affiliating Genes
1toxoplasmosis11.5
2calcific tendinitis10.5CD40LG, CD79A
3medullary sponge kidney10.5CD40LG, CD79A
4variola major10.5CD40LG, CD79A
5mu chain disease10.5CD40LG, CD79A
6retinal cancer10.5CD40LG, CD79A
7focal embolic glomerulonephritis10.5CD40LG, CD79A
8heart disease10.5CD40LG, CD79A
9endometrial stromal nodule10.5CD40LG, CD79A
10chronic cystitis10.5CD40LG, CD79A
11van benthem-driessen-hanveld syndrome10.5CD40LG, CD79A
12hemolytic-uremic syndrome10.5CD40LG, CD79A
13partial motor epilepsy10.5CD40LG, CD79A
14benign meningioma10.5CD40LG, CD79A
15parasitic helminthiasis infectious disease10.5CD40LG, CD79A
16occlusion of gallbladder10.5CD40LG, CD79A
17viral meningitis10.5CD40LG, CD79A
18substance-induced psychosis10.5CD40LG, CD79A
19gamma heavy chain disease10.5CD40LG, CD79A
20regional ureteric cancer10.5CD40LG, CD79A
21arteriosclerosis10.5CD40LG, CD79A
22pompholyx10.5CD40LG, CD79A
23bacterial conjunctivitis10.5CD40LG, CD79A
24deep keratitis10.5CD40LG, CD79A
25monoclonal paraproteinemia10.5CD40LG, CD79A
26cockayne syndrome10.5CD40LG, CD79A
27juvenile type testicular granulosa cell tumor10.5CD40LG, CD79A
28testicular brenner tumor10.5CD40LG, CD79A
29diabetic angiopathy10.5CD40LG, CD79A
30fallopian tube leiomyosarcoma10.5CD40LG, CD79A
31adult extraosseous chondrosarcoma10.5CD40LG, CD79A
32brucella abortus brucellosis10.5CD40LG, CD79A
33ganglioneuroblastoma10.5CD40LG, CD79A
34small intestinal vasoactive intestinal peptide producing tumor10.5CD40LG, CD79A
35aniseikonia10.5CD40LG, CD79A
36b cell linker protein deficiency10.5CD40LG, CD79A
37post-traumatic stress disorder10.5CD40LG, CD79A
38granular cell tumor10.5CD40LG, CD79A
39psoriasis10.5CD40LG, CD79A
40spinocerebellar ataxia, autosomal recessive 1010.5CD40LG, CD79A
41adie pupil10.5CD40LG, CD79A
42lambda 5 deficiency10.5CD40LG, CD79A
43lung abscess10.5CD40LG, CD79A
44hypoparathyroidism, x-linked10.5CD40LG, CD79A
45ileocolitis10.5CD40LG, CD79A
46glanders10.5CD40LG, CD79A
47peptic esophagitis10.5CD40LG, CD79A
48alcoholic neuropathy10.5CD40LG, CD79A
49mesangial proliferative glomerulonephritis10.5CD40LG, CD79A
50vestibule of mouth cancer10.5CD40LG, CD79A

Graphical network of the top 20 diseases related to Congenital Toxoplasmosis:



Diseases related to congenital toxoplasmosis

Symptoms for Congenital Toxoplasmosis

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Human phenotypes related to Congenital Toxoplasmosis:

 63 53 (show all 28)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 premature birth63 53 hallmark (90%) Very frequent (99-80%) HP:0001622
2 abnormality of retinal pigmentation63 53 hallmark (90%) Very frequent (99-80%) HP:0007703
3 visual impairment63 53 typical (50%) Occasional (29-5%) HP:0000505
4 hydrocephalus63 53 occasional (7.5%) Occasional (29-5%) HP:0000238
5 microcephaly63 53 occasional (7.5%) Occasional (29-5%) HP:0000252
6 hearing impairment63 53 occasional (7.5%) Occasional (29-5%) HP:0000365
7 nystagmus63 53 occasional (7.5%) Occasional (29-5%) HP:0000639
8 hypermelanotic macule63 occasional (7.5%) HP:0001034
9 seizures63 53 occasional (7.5%) Occasional (29-5%) HP:0001250
10 muscular hypotonia63 53 occasional (7.5%) Occasional (29-5%) HP:0001252
11 intrauterine growth retardation63 53 occasional (7.5%) Occasional (29-5%) HP:0001511
12 ascites63 53 occasional (7.5%) Occasional (29-5%) HP:0001541
13 cardiomegaly63 53 occasional (7.5%) Occasional (29-5%) HP:0001640
14 thrombocytopenia63 53 occasional (7.5%) Occasional (29-5%) HP:0001873
15 anemia63 53 occasional (7.5%) Occasional (29-5%) HP:0001903
16 diarrhea63 53 occasional (7.5%) Occasional (29-5%) HP:0002014
17 ventriculomegaly63 53 occasional (7.5%) Occasional (29-5%) HP:0002119
18 hepatomegaly63 53 occasional (7.5%) Occasional (29-5%) HP:0002240
19 cerebral calcification63 53 occasional (7.5%) Occasional (29-5%) HP:0002514
20 lymphadenopathy63 53 occasional (7.5%) Occasional (29-5%) HP:0002716
21 elevated hepatic transaminases63 53 occasional (7.5%) Occasional (29-5%) HP:0002910
22 aplasia/hypoplasia affecting the eye63 occasional (7.5%) HP:0008056
23 cognitive impairment63 53 occasional (7.5%) Occasional (29-5%) HP:0100543
24 microphthalmia53 Occasional (29-5%)
25 jaundice53 Occasional (29-5%)
26 global developmental delay53 Occasional (29-5%)
27 failure to thrive in infancy53 Occasional (29-5%)
28 macule53 Occasional (29-5%)

Drugs & Therapeutics for Congenital Toxoplasmosis

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Drugs for Congenital Toxoplasmosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 23)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
LevoleucovorinapprovedPhase 4, Phase 371168538-85-2
Synonyms:
(6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid
(6S)-5-formyltetrahydrofolic acid
(6S)-Folinic acid
(6S)-Leucovorin
 
(S)-Leucovorin
Citrovorum factor
L-Folinic acid
Levofolene
Levofolinic acid
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
2
Pyrimethamineapproved, vet_approvedPhase 4, Phase 315258-14-04993
Synonyms:
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
46706_FLUKA
46706_RIEDEL
4753 R.P.
4753 r.p
5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE
5-(4-CHLOROPHENYL)-6-ETHYL-2,4-PYRIMIDINEDIAMINE
5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidi nediamine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
5-(4-chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
5-(p-chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-[4-Chlorophenyl]-6-ethyl-2,4-pyrimidinediamine
58-14-0
AB00052084
AC-7879
AC1L1JDI
AI3-25005
AZT + Pyrimethamine combination
Aventis Brand of Pyrimethamine
BIDD:GT0149
BIDD:PXR0173
BPBio1_000147
BRD-K88429204-001-05-4
BRN 0219864
BSPBio_000133
BSPBio_003282
BW 50-63
BW 5063
C07391
C12H13ClN4
CAS-58-14-0
CCRIS 546
CD
CHEBI:8673
CHEMBL36
CID4993
CP6
CPD000058714
CRL-8131 & Pyrimethamine
CRL-8142 & Pyrimethamine
Chloridin
Chloridine
Chloridyn
D00488
D011739
DB00205
Darachlor
Daraclor
Darapram
Daraprim
Daraprim (TN)
Daraprime
Daraprin
Diaminopyritamin
Disulone
DivK1c_000652
EINECS 200-364-2
EXR-101
Erbaprelina
Ethylpyrimidine
Fansidar
Fansidar (Pyrimethamine/Sulfadoxine)
Glaxo Wellcome Brand of Pyrimethamine
GlaxoSmithKline Brand of Pyrimethamine
HMS1568G15
HMS1920N12
HMS2092E13
HMS502A14
IDI1_000652
KBio1_000652
KBio2_001386
KBio2_003954
 
KBio2_006522
KBio3_002502
KBioGR_001007
KBioSS_001386
Khloridin
L000713
LS-238
Lactoferrin B & Pyrimethamine
Lactoferrin H & Pyrimethamine
MCB-3837
MLS000028606
MLS001148621
MLS002454446
MLS002701881
Malacid
Malocid
Malocide
Maloprim
MolPort-001-783-655
NCGC00016256-01
NCGC00016256-02
NCGC00023188-03
NCGC00023188-04
NCGC00023188-05
NCGC00023188-06
NCGC00023188-07
NCI-C01683
NCI60_002604
NCIOpen2_008313
NINDS_000652
NSC 3061
NSC-3061
NSC3061
Oxaquin
Pirimecidan
Pirimetamin
Pirimetamina
Pirimetamina [INN-Spanish]
Pirimetamina [Spanish]
Prestwick0_000037
Prestwick1_000037
Prestwick2_000037
Prestwick3_000037
Prestwick_504
Primethamine
Pyremethamine
Pyrimethamin
Pyrimethamine (JAN/USP/INN)
Pyrimethamine (Pyr)
Pyrimethamine Hcl
Pyrimethamine [USAN:INN:BAN:JAN]
Pyrimethaminum
Pyrimethaminum [INN-Latin]
RP 4753
S2006_Selleck
SAM002554921
SMR000058714
SPBio_000672
SPBio_002054
SPECTRUM1500520
Spectrum2_000886
Spectrum3_001701
Spectrum4_000494
Spectrum5_001447
Spectrum_000906
TCMDC-123831
TCMDC-125860
Tindurin
Tindurine
Tinduring
UNII-Z3614QOX8W
WLN: T6N CNJ BZ DZ ER DG& F2
WR 2978
Wellcome Brand of Pyrimethamine
ZINC00057464
m alocid
nchembio.215-comp13
nchembio.87-comp22
pyrimethamine
3
SpiramycinapprovedPhase 4, Phase 3424916-50-5
Synonyms:
Demycarosylturimycin H
Foromacidine A
 
Spiramycin 1
Spiramycin A
foromacidin A
4
Sulfadiazineapproved, vet_approvedPhase 4, Phase 33268-35-95215
Synonyms:
141582-64-1
2-Sulfanilamido-pyrimidine
2-Sulfanilamidopyrimidin
2-Sulfanilamidopyrimidin [German]
2-Sulfanilamidopyrimidine
2-Sulfanilylaminopyrimidine
2-Sulfapyrimidine
2-sulfanilamidopyrimidine
2-sulfanilylaminopyrimidine
35033_FLUKA
35033_RIEDEL
4-AMINO-N-2-PYRIMIDINYLBENZENESULFONAMIDE
4-Amino-N-(2-pyrimidinyl)benzenesulfonamide
4-Amino-N-2-pyrimidinyl- benzenesulfonamide
4-Amino-N-2-pyrimidinyl-benzenesulfonamide
4-amino-N-(pyrimidin-2-yl)benzenesulfonamide
4-amino-N-2-pyrimidinylbenzenesulfonamide
4-amino-N-pyrimidin-2-ylbenzenesulfonamide
5-25-10-00067 (Beilstein Handbook Reference)
68-35-9
A 306
A-306
A-306 (VAN)
AB00052095
AC-12001
AC1L1JUR
AC1Q51XM
AC1Q6W1E
AI3-01047
AKOS000119073
AR-1L4215
Adiazin
Adiazin, Adiazine, Debenal, Liquadiazine, Microsulfon, Sulfazine, Sulfolex, Sulfadiazine
Adiazine
BB_SC-0628
BPBio1_000095
BRD-K32273377-001-05-4
BRN 0235192
BSPBio_000085
BSPBio_002884
C07658
C10H10N4O2S
CAS-68-35-9
CHEBI:9328
CHEMBL439
CID5215
CRL-8131 & Sulfadiazine
Coco-Diazine
CocoDiazine
Cocodiazine
Codiazine
Cremodiazine
Cremotres
D00587
D013411
DB00359
Debenal
Deltazina
Di-Azo-Mul
Diazin
Diazolone
Diazovit
Diazyl
DivK1c_000543
EINECS 200-685-8
Eskadiazine
HMS1568E07
HMS1921A13
HMS2090P09
HMS2092I15
HMS501L05
Honey Diazine
Honey diazine
IDI1_000543
KBio1_000543
KBio2_001466
KBio2_004034
KBio2_006602
KBio3_002104
KBioGR_000743
KBioSS_001466
LS-147838
Lantrisul
Lipo-Diazine
Lipo-Levazine
Liquadiazine
MLS000069423
Metha-Meridiazine
Microsulfon
Mixture of sulfadiazine, sulfamerazine, and sulfamethazine
MolPort-000-629-738
N(1)-2-Pyrimidinylsulfanilamide
N(1)-2-Pyrimidylsulfanilamide
N(1)-2-pyrimidinylsulfanilamide
N(1)-2-pyrimidylsulfanilamide
N(sup 1)-2-Pyrimidinylsulfanilamide
N(sup1)-2-Pyrimidinylsulfanilamide
N(sup1)-2-Pyrimidylsulfanilamide
N-(2-Pyrimidinyl)sulfanilamide
 
N1-(Pyrimidin-2-yl)sulfanilamide
N1-2-pyrimidinylsulfanilamide
N1-2-pyrimidylsulfanilamide
NCGC00016305-01
NCGC00016305-02
NCGC00023291-03
NCGC00023291-04
NINDS_000543
NSC 35600
NSC117870
NSC35600
Neazine
Neotrizine
Oprea1_081078
Palatrize
Pecta-Diazine
Pecta-diazine, suspension
Piridisir
Pirimal
Prestwick0_000023
Prestwick1_000023
Prestwick2_000023
Prestwick3_000023
Prestwick_428
Pyrimal
Quadetts
Quadramoid
RP 2616
Recombinant bactericidal/permeability-increasing protein & Sulfadiazine
S. N. 112
S.N. 112
S0579
S1770_Selleck
S8626_SIGMA
SDA
SMR000059113
SPBio_001417
SPBio_002006
SPECTRUM1500546
SSD
STK317797
Sanodiazine
Sildaflo
Silvadene
Solfadiazina
Solfadiazina [DCIT]
Spectrum2_001319
Spectrum3_001362
Spectrum4_000342
Spectrum5_000992
Spectrum_000986
Spofadrizine
Sterazine
Sulfa-Triple #2
Sulfacombin
Sulfadiazene
Sulfadiazin
Sulfadiazina
Sulfadiazina [INN-Spanish]
Sulfadiazine
Sulfadiazine (JAN/USP/INN)
Sulfadiazine (TN)
Sulfadiazine [USAN:INN:JAN]
Sulfadiazine, Zinc
Sulfadiazinum
Sulfadiazinum [INN-Latin]
Sulfaloid
Sulfanilamide, N1-2-pyrimidinyl- (8CI)
Sulfanilamidopyrimidine
Sulfapirimidin
Sulfapyrimidin
Sulfapyrimidin [German]
Sulfapyrimidine
Sulfatryl
Sulfazine
Sulfolex
Sulfonamides Duplex
Sulfonsol
Sulfose
Sulphadiazine
Sulphadiazine E
TL80073596
Terfonyl
Theradiazine
Thermazene
Thi-Di-Mer
Tri-Sulfameth
Trifonamide
Triple Sulfa
Triple Sulfas
Triple Sulfoid
Trisem
Trisulfapyrimidine, oral suspension
Truozine
UNII-0N7609K889
WLN: T6N CNJ BMSWR DZ
ZINC00120319
Zinc Sulfadiazine
rBPI21 & Sulfa
sulfadiazine
5
leucovorinapprovedPhase 4108958-05-9143, 54575
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
6
Folic Acidapproved, nutraceutical, vet_approvedPhase 4, Phase 3427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
7Anti-Bacterial AgentsPhase 4, Phase 310884
8Vitamin B ComplexPhase 4, Phase 34229
9Folic Acid AntagonistsPhase 4, Phase 32200
10Anti-Infective AgentsPhase 4, Phase 321402
11Antiparasitic AgentsPhase 4, Phase 32127
12AntimalarialsPhase 4, Phase 31216
13Antiprotozoal AgentsPhase 4, Phase 31986
14Trace ElementsPhase 45802
15AntidotesPhase 41038
16MicronutrientsPhase 45802
17Calcium, DietaryPhase 45525
18Protective AgentsPhase 47190
19Bone Density Conservation AgentsPhase 43266
20VitaminsPhase 45095
21Vitamin B9NutraceuticalPhase 4, Phase 34279
22Folinic AcidNutraceuticalPhase 4, Phase 33150
23FolateNutraceuticalPhase 4, Phase 34279

Interventional clinical trials:

idNameStatusNCT IDPhase
1Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital ToxoplasmosisRecruitingNCT00004317Phase 4
2Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital ToxoplasmosisUnknown statusNCT01202500Phase 3
3Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During PregnancyCompletedNCT01189448Phase 3
4Lyon Cohort of Maternal and Congenital Toxoplasma InfectionsRecruitingNCT02936921
5Expanded Noninvasive Genomic Medical Assessment: The Enigma StudyRecruitingNCT02787486

Search NIH Clinical Center for Congenital Toxoplasmosis


Cochrane evidence based reviews: toxoplasmosis, congenital

Genetic Tests for Congenital Toxoplasmosis

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Anatomical Context for Congenital Toxoplasmosis

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MalaCards organs/tissues related to Congenital Toxoplasmosis:

35
Testes, Eye, Brain, Bone, Placenta, Temporal lobe, Pituitary

Animal Models for Congenital Toxoplasmosis or affiliated genes

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Publications for Congenital Toxoplasmosis

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Articles related to Congenital Toxoplasmosis:

(show top 50)    (show all 555)
idTitleAuthorsYear
1
Congenital Toxoplasmosis in Chronically Infected and Subsequently Challenged Ewes. (27788185)
2016
2
Incidence of Symptomatic Congenital Toxoplasmosis During 10 Years in a Brazilian Hospital. (27455439)
2016
3
Incidence of congenital toxoplasmosis among infants born to HIV-coinfected mothers: case series and literature review. (25017666)
2014
4
A dedicated surveillance network for congenital toxoplasmosis in Greece, 2006-2009: assessment of the results. (23173875)
2012
5
Toxoplasma gondii antibody profile in HIV-1-infected and uninfected pregnant women and the impact on congenital toxoplasmosis diagnosis in Rio de Janeiro, Brazil. (22552460)
2012
6
Spinal Cord Lesions in Congenital Toxoplasmosis Demonstrated with Neuroimaging, Including Their Successful Treatment in an Adult. (23487348)
2012
7
Congenital toxoplasmosis in a neonate with significant neurologic manifestations. (22526213)
2012
8
Geographic difference in outcomes of congenital toxoplasmosis. (21849862)
2011
9
Congenital toxoplasmosis treatment (21434486)
2011
10
Congenital toxoplasmosis--a report on the Danish neonatal screening programme 1999-2007. (20585987)
2010
11
Congenital toxoplasmosis from a chronically infected woman with reactivation of retinochoroiditis during pregnancy. (19918624)
2010
12
In utero and at birth diagnosis of congenital toxoplasmosis: use of likelihood ratios for clinical management. (19952858)
2010
13
Survey of European programmes for the epidemiological surveillance of congenital toxoplasmosis. (18445459)
2008
14
Hearing loss in congenital toxoplasmosis detected by newborn screening. (18392497)
2008
15
Genetic and epigenetic factors at COL2A1 and ABCA4 influence clinical outcome in congenital toxoplasmosis. (18523590)
2008
16
Congenital toxoplasmosis: priorities for further health promotion action. (17964621)
2008
17
Disease burden of congenital toxoplasmosis. (17479945)
2007
18
Risk factors for Toxoplasma gondii infection in mothers of infants with congenital toxoplasmosis: implications for prenatal management and screening. (16458668)
2006
19
Congenital toxoplasmosis complicated with central diabetes insipidus in the first week of life. (16492446)
2006
20
Prenatal diagnosis of congenital toxoplasmosis: is there a chance for the pregnancies in settings without surveillance programs? (16260894)
2005
21
Toxopain-1 is critical for infection in a novel chicken embryo model of congenital toxoplasmosis. (15102804)
2004
22
Sulfadiazine and pyrimethamine in the postnatal treatment of congenital toxoplasmosis: what are the options? (15482110)
2003
23
Vaccination with Toxoplasma gondii SAG-1 protein is protective against congenital toxoplasmosis in BALB/c mice but not in CBA/J mice. (14573684)
2003
24
Prospective study of pregnants and babies with risk of congenital toxoplasmosis in municipal district of Rio Grande do Sul]. (12937726)
2003
25
Congenital toxoplasmosis in Israel: to screen or not to screen. (11875985)
2002
26
Preconception seroconversion and maternal seronegativity at delivery do not rule out the risk of congenital toxoplasmosis. (11874899)
2002
27
Congenital toxoplasmosis: eye manifestations in infants and children. (12369484)
2002
28
Strategy for diagnosis of congenital toxoplasmosis: evaluation of methods comparing mothers and newborns and standard methods for postnatal detection of immunoglobulin G, M, and A antibodies. (11376068)
2001
29
Bax-induced apoptosis not demonstrated in the congenital toxoplasmosis in mice. (11226731)
2001
30
Congenital toxoplasmosis, later relapses and treatment. (10419236)
1999
31
Congenital toxoplasmosis: prenatal diagnosis, treatment and postnatal outcome. (10327137)
1999
32
Prenatal diagnosis of congenital toxoplasmosis by PCR: extended experience. (9602492)
1998
33
The role of IL-4 in adult acquired and congenital toxoplasmosis. (9504339)
1998
34
Evaluation of the possibilities for preventing congenital toxoplasmosis. (8155214)
1994
35
Rat model of congenital toxoplasmosis: rate of transmission of three Toxoplasma gondii strains to fetuses and protective effect of a chronic infection. (8418062)
1993
36
Ultrastructural immunocytochemistry of the intact tissue cyst of Toxoplasma in the brains of mice with congenital toxoplasmosis. (2383094)
1990
37
Congenital toxoplasmosis in Abyssinian cats. (2773276)
1989
38
An electron microscope and immunohistochemical study of the intracellular location of Toxoplasma tissue cysts within the brains of mice with congenital toxoplasmosis. (2504268)
1989
39
Host-parasite relationship in the brains of mice with congenital toxoplasmosis. (3204455)
1988
40
Prophylaxis of congenital toxoplasmosis. Effects of spiramycin on placental infection. (3182443)
1988
41
Prenatal management and congenital toxoplasmosis. (3393202)
1988
42
Congenital toxoplasmosis: epidemiologic features and control. (3756692)
1986
43
Meningo-encephalitis accompanying retinochoroiditis in a murine model of congenital toxoplasmosis. (3985703)
1985
44
Congenital toxoplasmosis associated with acquired oculomotor nerve (CN III) palsy. (7175624)
1982
45
In vitro lymphocyte stimulation with specific antigen in congenital toxoplasmosis. (7031854)
1981
46
Congenital toxoplasmosis. (6103223)
1980
47
Congenital toxoplasmosis. (7395823)
1980
48
Congenital toxoplasmosis in Tasmania. (651703)
1978
49
An estimation of the incidence of congenital toxoplasmosis in SALo Paulo city, Brasil. (951563)
1976
50
Cholelithiasis in the newborn infant in association with congenital toxoplasmosis and hereditary elliptocytosis. (5946658)
1966

Variations for Congenital Toxoplasmosis

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Expression for genes affiliated with Congenital Toxoplasmosis

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Search GEO for disease gene expression data for Congenital Toxoplasmosis.

Pathways for genes affiliated with Congenital Toxoplasmosis

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Pathways related to Congenital Toxoplasmosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7CD40LG, CD79A
29.6CD40LG, COL2A1
39.1CD40LG, CD79A, NLRP1

GO Terms for genes affiliated with Congenital Toxoplasmosis

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Biological processes related to Congenital Toxoplasmosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1B cell proliferationGO:00421009.9CD40LG, CD79A
2B cell differentiationGO:00301839.8CD40LG, CD79A
3visual perceptionGO:00076019.0ABCA4, COL2A1, NRL

Sources for Congenital Toxoplasmosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet