MCID: CNG021
MIFTS: 46

Congenital Toxoplasmosis malady

Categories: Fetal diseases, Neuronal diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Congenital Toxoplasmosis

About this section
Sources:
11Disease Ontology, 46NIH Rare Diseases, 13DISEASES, 52Orphanet, 48Novoseek, 37MeSH, 66UMLS, 28ICD10, 43NCIt, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Congenital Toxoplasmosis:

Name: Congenital Toxoplasmosis 11 46 13 52
Toxoplasmosis, Congenital 37 66
Toxoplasma Embryofetopathy 52
 
Toxoplasmosis Congenital 48
Toxoplasmosis - Congen. 11
Toxoplasma Embryopathy 52

Characteristics:

Orphanet epidemiological data:

52
congenital toxoplasmosis:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe),1-5/10000 (United States); Age of onset: Adolescent,Adult,Antenatal,Childhood,Infancy,Neonatal

Classifications:



External Ids:

Disease Ontology11 DOID:13336
ICD1028 P37.1
MeSH37 D014125
NCIt43 C50503
Orphanet52 ORPHA858
ICD10 via Orphanet29 P37.1
MESH via Orphanet38 D014125
UMLS via Orphanet67 C0040560

Summaries for Congenital Toxoplasmosis

About this section
Disease Ontology:11 A toxoplasmosis that involves a reactivated infection of the mother transmitted to the fetus during pregnancy. spontaneous abortion and stillbirth may occur.

MalaCards based summary: Congenital Toxoplasmosis, also known as toxoplasmosis, congenital, is related to toxoplasmosis and stickler sydrome, type i, nonsyndromic ocular, and has symptoms including premature birth, abnormality of retinal pigmentation and visual impairment. An important gene associated with Congenital Toxoplasmosis is CD40LG (CD40 Ligand), and among its related pathways are Primary immunodeficiency and T Cell Co-Signaling Pathway: Ligand-Receptor Interactions. Affiliated tissues include testes, eye and brain.

Related Diseases for Congenital Toxoplasmosis

About this section

Diseases in the Toxoplasmosis family:

congenital toxoplasmosis

Diseases related to Congenital Toxoplasmosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 194)
idRelated DiseaseScoreTop Affiliating Genes
1toxoplasmosis11.4
2stickler sydrome, type i, nonsyndromic ocular10.4CD40LG, COL2A1
3calcific tendinitis10.3CD40LG, CD79A
4medullary sponge kidney10.3CD40LG, CD79A
5variola major10.3CD40LG, CD79A
6mu chain disease10.3CD40LG, CD79A
7calcium metabolism disease10.3CD40LG, CD79A
8retinal cancer10.3CD40LG, CD79A
9focal embolic glomerulonephritis10.3CD40LG, CD79A
10membranous glomerulonephritis10.3CD40LG, CD79A
11heart disease10.3CD40LG, CD79A
12endometrial stromal nodule10.3CD40LG, CD79A
13chronic cystitis10.3CD40LG, CD79A
14van benthem-driessen-hanveld syndrome10.3CD40LG, CD79A
15hemolytic-uremic syndrome10.3CD40LG, CD79A
16partial motor epilepsy10.3CD40LG, CD79A
17benign meningioma10.3CD40LG, CD79A
18parasitic helminthiasis infectious disease10.2CD40LG, CD79A
19occlusion of gallbladder10.2CD40LG, CD79A
20viral meningitis10.2CD40LG, CD79A
21substance-induced psychosis10.2CD40LG, CD79A
22gamma heavy chain disease10.2CD40LG, CD79A
23regional ureteric cancer10.2CD40LG, CD79A
24arteriosclerosis10.2CD40LG, CD79A
25pompholyx10.2CD40LG, CD79A
26bacterial conjunctivitis10.2CD40LG, CD79A
27deep keratitis10.2CD40LG, CD79A
28monoclonal paraproteinemia10.2CD40LG, CD79A
29cockayne syndrome10.2CD40LG, CD79A
30juvenile type testicular granulosa cell tumor10.2CD40LG, CD79A
31testicular brenner tumor10.2CD40LG, CD79A
32oculo cerebro osseous syndrome10.2CD40LG, CD79A
33diabetic angiopathy10.2CD40LG, CD79A
34fallopian tube leiomyosarcoma10.2CD40LG, CD79A
35adult extraosseous chondrosarcoma10.2CD40LG, CD79A
36brucella abortus brucellosis10.2CD40LG, CD79A
37ganglioneuroblastoma10.2CD40LG, CD79A
38small intestinal vasoactive intestinal peptide producing tumor10.2CD40LG, CD79A
39aniseikonia10.2CD40LG, CD79A
40b cell linker protein deficiency10.2CD40LG, CD79A
41post-traumatic stress disorder10.2CD40LG, CD79A
42granular cell tumor10.2CD40LG, CD79A
43psoriasis10.2CD40LG, CD79A
44spinocerebellar ataxia, autosomal recessive 1010.2CD40LG, CD79A
45adie pupil10.2CD40LG, CD79A
46lambda 5 deficiency10.2CD40LG, CD79A
47lung abscess10.2CD40LG, CD79A
48hypoparathyroidism, x-linked10.2CD40LG, CD79A
49ileocolitis10.2CD40LG, CD79A
50glanders10.2CD40LG, CD79A

Graphical network of the top 20 diseases related to Congenital Toxoplasmosis:



Diseases related to congenital toxoplasmosis

Symptoms for Congenital Toxoplasmosis

About this section

Symptoms:

 52 (show all 26)
  • hydrocephalus
  • microcephaly
  • hearing impairment
  • visual impairment
  • microphthalmos
  • nystagmus
  • jaundice
  • seizures
  • muscular hypotonia
  • global developmental delay
  • intrauterine growth retardation
  • failure to thrive in infancy
  • ascites
  • premature birth
  • cardiomegaly
  • thrombocytopenia
  • anemia
  • diarrhea
  • ventriculomegaly
  • hepatomegaly
  • cerebral calcification
  • lymphadenopathy
  • elevated hepatic transaminases
  • abnormal retinal pigmentation
  • macule
  • cognitive impairment

HPO human phenotypes related to Congenital Toxoplasmosis:

(show all 24)
id Description Frequency HPO Source Accession
1 premature birth hallmark (90%) HP:0001622
2 abnormality of retinal pigmentation hallmark (90%) HP:0007703
3 visual impairment typical (50%) HP:0000505
4 hydrocephalus occasional (7.5%) HP:0000238
5 microcephaly occasional (7.5%) HP:0000252
6 hearing impairment occasional (7.5%) HP:0000365
7 visual impairment occasional (7.5%) HP:0000505
8 nystagmus occasional (7.5%) HP:0000639
9 hypermelanotic macule occasional (7.5%) HP:0001034
10 seizures occasional (7.5%) HP:0001250
11 muscular hypotonia occasional (7.5%) HP:0001252
12 intrauterine growth retardation occasional (7.5%) HP:0001511
13 ascites occasional (7.5%) HP:0001541
14 cardiomegaly occasional (7.5%) HP:0001640
15 thrombocytopenia occasional (7.5%) HP:0001873
16 anemia occasional (7.5%) HP:0001903
17 diarrhea occasional (7.5%) HP:0002014
18 ventriculomegaly occasional (7.5%) HP:0002119
19 hepatomegaly occasional (7.5%) HP:0002240
20 cerebral calcification occasional (7.5%) HP:0002514
21 lymphadenopathy occasional (7.5%) HP:0002716
22 elevated hepatic transaminases occasional (7.5%) HP:0002910
23 aplasia/hypoplasia affecting the eye occasional (7.5%) HP:0008056
24 cognitive impairment occasional (7.5%) HP:0100543

Drugs & Therapeutics for Congenital Toxoplasmosis

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Drugs for Congenital Toxoplasmosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
PyrimethaminePhase 4, Phase 315158-14-04993
Synonyms:
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine
2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine
46706_FLUKA
46706_RIEDEL
4753 R.P.
4753 r.p
5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE
5-(4-CHLOROPHENYL)-6-ETHYL-2,4-PYRIMIDINEDIAMINE
5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidi nediamine
5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
5-(4-chlorophenyl)-2,4-diamino-6-ethylpyrimidine
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
5-(p-chlorophenyl)-6-ethyl-2,4-diaminopyrimidine
5-[4-Chlorophenyl]-6-ethyl-2,4-pyrimidinediamine
58-14-0
AB00052084
AC-7879
AC1L1JDI
AI3-25005
AZT + Pyrimethamine combination
Aventis Brand of Pyrimethamine
BIDD:GT0149
BIDD:PXR0173
BPBio1_000147
BRD-K88429204-001-05-4
BRN 0219864
BSPBio_000133
BSPBio_003282
BW 50-63
BW 5063
C07391
C12H13ClN4
CAS-58-14-0
CCRIS 546
CD
CHEBI:8673
CHEMBL36
CID4993
CP6
CPD000058714
CRL-8131 & Pyrimethamine
CRL-8142 & Pyrimethamine
Chloridin
Chloridine
Chloridyn
D00488
D011739
DB00205
Darachlor
Daraclor
Darapram
Daraprim
Daraprim (TN)
Daraprime
Daraprin
Diaminopyritamin
Disulone
DivK1c_000652
EINECS 200-364-2
EXR-101
Erbaprelina
Ethylpyrimidine
Fansidar
Fansidar (Pyrimethamine/Sulfadoxine)
Glaxo Wellcome Brand of Pyrimethamine
GlaxoSmithKline Brand of Pyrimethamine
HMS1568G15
HMS1920N12
HMS2092E13
HMS502A14
IDI1_000652
KBio1_000652
KBio2_001386
KBio2_003954
 
KBio2_006522
KBio3_002502
KBioGR_001007
KBioSS_001386
Khloridin
L000713
LS-238
Lactoferrin B & Pyrimethamine
Lactoferrin H & Pyrimethamine
MCB-3837
MLS000028606
MLS001148621
MLS002454446
MLS002701881
Malacid
Malocid
Malocide
Maloprim
MolPort-001-783-655
NCGC00016256-01
NCGC00016256-02
NCGC00023188-03
NCGC00023188-04
NCGC00023188-05
NCGC00023188-06
NCGC00023188-07
NCI-C01683
NCI60_002604
NCIOpen2_008313
NINDS_000652
NSC 3061
NSC-3061
NSC3061
Oxaquin
Pirimecidan
Pirimetamin
Pirimetamina
Pirimetamina [INN-Spanish]
Pirimetamina [Spanish]
Prestwick0_000037
Prestwick1_000037
Prestwick2_000037
Prestwick3_000037
Prestwick_504
Primethamine
Pyremethamine
Pyrimethamin
Pyrimethamine (JAN/USP/INN)
Pyrimethamine (Pyr)
Pyrimethamine Hcl
Pyrimethamine [USAN:INN:BAN:JAN]
Pyrimethaminum
Pyrimethaminum [INN-Latin]
RP 4753
S2006_Selleck
SAM002554921
SMR000058714
SPBio_000672
SPBio_002054
SPECTRUM1500520
Spectrum2_000886
Spectrum3_001701
Spectrum4_000494
Spectrum5_001447
Spectrum_000906
TCMDC-123831
TCMDC-125860
Tindurin
Tindurine
Tinduring
UNII-Z3614QOX8W
WLN: T6N CNJ BZ DZ ER DG& F2
WR 2978
Wellcome Brand of Pyrimethamine
ZINC00057464
m alocid
nchembio.215-comp13
nchembio.87-comp22
pyrimethamine
2
SulfadiazinePhase 4, Phase 33368-35-95215
Synonyms:
141582-64-1
2-Sulfanilamido-pyrimidine
2-Sulfanilamidopyrimidin
2-Sulfanilamidopyrimidin [German]
2-Sulfanilamidopyrimidine
2-Sulfanilylaminopyrimidine
2-Sulfapyrimidine
2-sulfanilamidopyrimidine
2-sulfanilylaminopyrimidine
35033_FLUKA
35033_RIEDEL
4-AMINO-N-2-PYRIMIDINYLBENZENESULFONAMIDE
4-Amino-N-(2-pyrimidinyl)benzenesulfonamide
4-Amino-N-2-pyrimidinyl- benzenesulfonamide
4-Amino-N-2-pyrimidinyl-benzenesulfonamide
4-amino-N-(pyrimidin-2-yl)benzenesulfonamide
4-amino-N-2-pyrimidinylbenzenesulfonamide
4-amino-N-pyrimidin-2-ylbenzenesulfonamide
5-25-10-00067 (Beilstein Handbook Reference)
68-35-9
A 306
A-306
A-306 (VAN)
AB00052095
AC-12001
AC1L1JUR
AC1Q51XM
AC1Q6W1E
AI3-01047
AKOS000119073
AR-1L4215
Adiazin
Adiazin, Adiazine, Debenal, Liquadiazine, Microsulfon, Sulfazine, Sulfolex, Sulfadiazine
Adiazine
BB_SC-0628
BPBio1_000095
BRD-K32273377-001-05-4
BRN 0235192
BSPBio_000085
BSPBio_002884
C07658
C10H10N4O2S
CAS-68-35-9
CHEBI:9328
CHEMBL439
CID5215
CRL-8131 & Sulfadiazine
Coco-Diazine
CocoDiazine
Cocodiazine
Codiazine
Cremodiazine
Cremotres
D00587
D013411
DB00359
Debenal
Deltazina
Di-Azo-Mul
Diazin
Diazolone
Diazovit
Diazyl
DivK1c_000543
EINECS 200-685-8
Eskadiazine
HMS1568E07
HMS1921A13
HMS2090P09
HMS2092I15
HMS501L05
Honey Diazine
Honey diazine
IDI1_000543
KBio1_000543
KBio2_001466
KBio2_004034
KBio2_006602
KBio3_002104
KBioGR_000743
KBioSS_001466
LS-147838
Lantrisul
Lipo-Diazine
Lipo-Levazine
Liquadiazine
MLS000069423
Metha-Meridiazine
Microsulfon
Mixture of sulfadiazine, sulfamerazine, and sulfamethazine
MolPort-000-629-738
N(1)-2-Pyrimidinylsulfanilamide
N(1)-2-Pyrimidylsulfanilamide
N(1)-2-pyrimidinylsulfanilamide
N(1)-2-pyrimidylsulfanilamide
N(sup 1)-2-Pyrimidinylsulfanilamide
N(sup1)-2-Pyrimidinylsulfanilamide
N(sup1)-2-Pyrimidylsulfanilamide
N-(2-Pyrimidinyl)sulfanilamide
 
N1-(Pyrimidin-2-yl)sulfanilamide
N1-2-pyrimidinylsulfanilamide
N1-2-pyrimidylsulfanilamide
NCGC00016305-01
NCGC00016305-02
NCGC00023291-03
NCGC00023291-04
NINDS_000543
NSC 35600
NSC117870
NSC35600
Neazine
Neotrizine
Oprea1_081078
Palatrize
Pecta-Diazine
Pecta-diazine, suspension
Piridisir
Pirimal
Prestwick0_000023
Prestwick1_000023
Prestwick2_000023
Prestwick3_000023
Prestwick_428
Pyrimal
Quadetts
Quadramoid
RP 2616
Recombinant bactericidal/permeability-increasing protein & Sulfadiazine
S. N. 112
S.N. 112
S0579
S1770_Selleck
S8626_SIGMA
SDA
SMR000059113
SPBio_001417
SPBio_002006
SPECTRUM1500546
SSD
STK317797
Sanodiazine
Sildaflo
Silvadene
Solfadiazina
Solfadiazina [DCIT]
Spectrum2_001319
Spectrum3_001362
Spectrum4_000342
Spectrum5_000992
Spectrum_000986
Spofadrizine
Sterazine
Sulfa-Triple #2
Sulfacombin
Sulfadiazene
Sulfadiazin
Sulfadiazina
Sulfadiazina [INN-Spanish]
Sulfadiazine
Sulfadiazine (JAN/USP/INN)
Sulfadiazine (TN)
Sulfadiazine [USAN:INN:JAN]
Sulfadiazine, Zinc
Sulfadiazinum
Sulfadiazinum [INN-Latin]
Sulfaloid
Sulfanilamide, N1-2-pyrimidinyl- (8CI)
Sulfanilamidopyrimidine
Sulfapirimidin
Sulfapyrimidin
Sulfapyrimidin [German]
Sulfapyrimidine
Sulfatryl
Sulfazine
Sulfolex
Sulfonamides Duplex
Sulfonsol
Sulfose
Sulphadiazine
Sulphadiazine E
TL80073596
Terfonyl
Theradiazine
Thermazene
Thi-Di-Mer
Tri-Sulfameth
Trifonamide
Triple Sulfa
Triple Sulfas
Triple Sulfoid
Trisem
Trisulfapyrimidine, oral suspension
Truozine
UNII-0N7609K889
WLN: T6N CNJ BMSWR DZ
ZINC00120319
Zinc Sulfadiazine
rBPI21 & Sulfa
sulfadiazine
3
LevoleucovorinPhase 4, Phase 369668538-85-2
Synonyms:
(6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid
(6S)-5-formyltetrahydrofolic acid
(6S)-Folinic acid
(6S)-Leucovorin
 
(S)-Leucovorin
Citrovorum factor
L-Folinic acid
Levofolene
Levofolinic acid
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
4
leucovorinPhase 4104758-05-9143, 54575
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
5
Folic AcidNutraceuticalPhase 4, Phase 3414359-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
6FolateNutraceuticalPhase 4, Phase 34143

Interventional clinical trials:

idNameStatusNCT IDPhase
1Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital ToxoplasmosisRecruitingNCT00004317Phase 4
2Prevention of Congenital Toxoplasmosis With Pyrimethamine + Sulfadiazine Versus Spiramycine During PregnancyCompletedNCT01189448Phase 3
3Assessment of Two Therapeutic Strategies in the Treatment of Children With Congenital ToxoplasmosisRecruitingNCT01202500Phase 3
4Expanded Noninvasive Genomic Medical Assessment: The Enigma StudyRecruitingNCT02787486

Search NIH Clinical Center for Congenital Toxoplasmosis


Cochrane evidence based reviews: toxoplasmosis, congenital

Genetic Tests for Congenital Toxoplasmosis

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Anatomical Context for Congenital Toxoplasmosis

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MalaCards organs/tissues related to Congenital Toxoplasmosis:

34
Testes, Eye, Brain, Placenta, Temporal lobe, Pituitary, Fetal brain

Animal Models for Congenital Toxoplasmosis or affiliated genes

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Publications for Congenital Toxoplasmosis

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Articles related to Congenital Toxoplasmosis:

(show top 50)    (show all 552)
idTitleAuthorsYear
1
Incidence of Symptomatic Congenital Toxoplasmosis During 10 Years in a Brazilian Hospital. (27455439)
2016
2
Incidence of congenital toxoplasmosis among infants born to HIV-coinfected mothers: case series and literature review. (25017666)
2014
3
A dedicated surveillance network for congenital toxoplasmosis in Greece, 2006-2009: assessment of the results. (23173875)
2012
4
Toxoplasma gondii antibody profile in HIV-1-infected and uninfected pregnant women and the impact on congenital toxoplasmosis diagnosis in Rio de Janeiro, Brazil. (22552460)
2012
5
Spinal Cord Lesions in Congenital Toxoplasmosis Demonstrated with Neuroimaging, Including Their Successful Treatment in an Adult. (23487348)
2012
6
Congenital toxoplasmosis in a neonate with significant neurologic manifestations. (22526213)
2012
7
Geographic difference in outcomes of congenital toxoplasmosis. (21849862)
2011
8
Congenital toxoplasmosis treatment (21434486)
2011
9
Congenital toxoplasmosis--a report on the Danish neonatal screening programme 1999-2007. (20585987)
2010
10
Congenital toxoplasmosis from a chronically infected woman with reactivation of retinochoroiditis during pregnancy. (19918624)
2010
11
In utero and at birth diagnosis of congenital toxoplasmosis: use of likelihood ratios for clinical management. (19952858)
2010
12
Survey of European programmes for the epidemiological surveillance of congenital toxoplasmosis. (18445459)
2008
13
Hearing loss in congenital toxoplasmosis detected by newborn screening. (18392497)
2008
14
Genetic and epigenetic factors at COL2A1 and ABCA4 influence clinical outcome in congenital toxoplasmosis. (18523590)
2008
15
Congenital toxoplasmosis: priorities for further health promotion action. (17964621)
2008
16
Disease burden of congenital toxoplasmosis. (17479945)
2007
17
Risk factors for Toxoplasma gondii infection in mothers of infants with congenital toxoplasmosis: implications for prenatal management and screening. (16458668)
2006
18
Congenital toxoplasmosis complicated with central diabetes insipidus in the first week of life. (16492446)
2006
19
Prenatal diagnosis of congenital toxoplasmosis: is there a chance for the pregnancies in settings without surveillance programs? (16260894)
2005
20
Toxopain-1 is critical for infection in a novel chicken embryo model of congenital toxoplasmosis. (15102804)
2004
21
Sulfadiazine and pyrimethamine in the postnatal treatment of congenital toxoplasmosis: what are the options? (15482110)
2003
22
Vaccination with Toxoplasma gondii SAG-1 protein is protective against congenital toxoplasmosis in BALB/c mice but not in CBA/J mice. (14573684)
2003
23
Prospective study of pregnants and babies with risk of congenital toxoplasmosis in municipal district of Rio Grande do Sul]. (12937726)
2003
24
Congenital toxoplasmosis with unusual retinal findings. (12912703)
2003
25
Congenital toxoplasmosis in Israel: to screen or not to screen. (11875985)
2002
26
Preconception seroconversion and maternal seronegativity at delivery do not rule out the risk of congenital toxoplasmosis. (11874899)
2002
27
Congenital toxoplasmosis: eye manifestations in infants and children. (12369484)
2002
28
Strategy for diagnosis of congenital toxoplasmosis: evaluation of methods comparing mothers and newborns and standard methods for postnatal detection of immunoglobulin G, M, and A antibodies. (11376068)
2001
29
Bax-induced apoptosis not demonstrated in the congenital toxoplasmosis in mice. (11226731)
2001
30
Congenital toxoplasmosis, later relapses and treatment. (10419236)
1999
31
Congenital toxoplasmosis: prenatal diagnosis, treatment and postnatal outcome. (10327137)
1999
32
Prenatal diagnosis of congenital toxoplasmosis by PCR: extended experience. (9602492)
1998
33
The role of IL-4 in adult acquired and congenital toxoplasmosis. (9504339)
1998
34
Evaluation of the possibilities for preventing congenital toxoplasmosis. (8155214)
1994
35
Rat model of congenital toxoplasmosis: rate of transmission of three Toxoplasma gondii strains to fetuses and protective effect of a chronic infection. (8418062)
1993
36
Ultrastructural immunocytochemistry of the intact tissue cyst of Toxoplasma in the brains of mice with congenital toxoplasmosis. (2383094)
1990
37
Congenital toxoplasmosis in Abyssinian cats. (2773276)
1989
38
An electron microscope and immunohistochemical study of the intracellular location of Toxoplasma tissue cysts within the brains of mice with congenital toxoplasmosis. (2504268)
1989
39
Host-parasite relationship in the brains of mice with congenital toxoplasmosis. (3204455)
1988
40
Prophylaxis of congenital toxoplasmosis. Effects of spiramycin on placental infection. (3182443)
1988
41
Prenatal management and congenital toxoplasmosis. (3393202)
1988
42
Congenital toxoplasmosis: epidemiologic features and control. (3756692)
1986
43
Meningo-encephalitis accompanying retinochoroiditis in a murine model of congenital toxoplasmosis. (3985703)
1985
44
Congenital toxoplasmosis associated with acquired oculomotor nerve (CN III) palsy. (7175624)
1982
45
In vitro lymphocyte stimulation with specific antigen in congenital toxoplasmosis. (7031854)
1981
46
Congenital toxoplasmosis. (6103223)
1980
47
Congenital toxoplasmosis. (7395823)
1980
48
Congenital toxoplasmosis in Tasmania. (651703)
1978
49
An estimation of the incidence of congenital toxoplasmosis in SALo Paulo city, Brasil. (951563)
1976
50
Cholelithiasis in the newborn infant in association with congenital toxoplasmosis and hereditary elliptocytosis. (5946658)
1966

Variations for Congenital Toxoplasmosis

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Expression for genes affiliated with Congenital Toxoplasmosis

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Search GEO for disease gene expression data for Congenital Toxoplasmosis.

Pathways for genes affiliated with Congenital Toxoplasmosis

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Pathways related to Congenital Toxoplasmosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7CD40LG, CD79A
29.6CD40LG, COL2A1
39.1CD40LG, CD79A, NLRP1

GO Terms for genes affiliated with Congenital Toxoplasmosis

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Cellular components related to Congenital Toxoplasmosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098978.9CD40LG, CD79A, CD9

Biological processes related to Congenital Toxoplasmosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1B cell differentiationGO:00301839.7CD40LG, CD79A
2B cell proliferationGO:00421009.6CD40LG, CD79A

Sources for Congenital Toxoplasmosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet