Aliases & Classifications for Congestive Heart Failure

MalaCards integrated aliases for Congestive Heart Failure:

Name: Congestive Heart Failure 37 12 72 28 14 69
Heart Failure 41 69
Cardiac Failure Congestive 12
Congestive Heart Disease 12
Heart Failure Congestive 51
Weak Heart 12
Chf 12

Classifications:



Summaries for Congestive Heart Failure

Disease Ontology : 12 A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.

MalaCards based summary : Congestive Heart Failure, also known as heart failure, is related to pulmonary edema and congenital hepatic fibrosis, and has symptoms including syncope, edema and equilibration disorder. An important gene associated with Congestive Heart Failure is NPPA (Natriuretic Peptide A), and among its related pathways/superpathways are Cardiac conduction and Aldosterone synthesis and secretion. The drugs Alogliptin and Linagliptin have been mentioned in the context of this disorder. Affiliated tissues include Adipose and Lateral Plate Mesoderm, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : 72 Heart failure (HF), often referred to as congestive heart failure (CHF), occurs when the heart is unable... more...

Related Diseases for Congestive Heart Failure

Diseases related to Congestive Heart Failure via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 361)
# Related Disease Score Top Affiliating Genes
1 pulmonary edema 32.6 ACE EDN1 NPPB REN
2 congenital hepatic fibrosis 32.4 AGTR1 REN
3 orthostatic intolerance 31.8 ADRB1 ADRB2 AGTR1 EDN1
4 sleep apnea 31.4 ACE EDN1 NPPB REN
5 mitral valve disease 31.2 ACE AGTR1 NPPA
6 atrial fibrillation 31.2 ACE ADRB1 AGTR1 NPPA NPPB
7 central sleep apnea 30.8 NPPA NPPB
8 acute myocardial infarction 30.8 ACE ADRB1 EDN1 NPPA NPPB
9 diastolic heart failure 30.7 ACE AGTR1 NPPB
10 hypertensive heart disease 30.5 ACE AGTR1 NPPB NPR1 NR3C2
11 hypertrophic cardiomyopathy 30.5 ACE MYH6 MYH7 NPPB
12 syndrome of inappropriate antidiuretic hormone 30.5 ACE NPPA NPPB
13 mitral valve insufficiency 30.5 ACE NPPA NPPB
14 chronic kidney failure 30.5 ACE AGTR1 EDN1 EPO NPPB REN
15 aortic valve disease 1 30.4 ACE NPPB REN
16 postural hypotension 30.4 NPPA REN
17 arteries, anomalies of 30.4 ACE AGTR1 EDN1 KNG1 NPPB REN
18 kidney disease 30.3 ACE AGTR1 EDN1 EPO NPPA NPPB
19 chagas disease 30.3 ACE ADRB1 NPPB
20 tetralogy of fallot 30.2 EDN1 NPPA NPPB REN
21 end stage renal failure 30.2 ACE AGTR1 EPO
22 liver cirrhosis 30.2 EDN1 NPPA REN UTS2
23 ischemia 30.2 ACE EDN1 EPO KNG1
24 pulmonary hypertension 30.2 ACE ADM EDN1 NPPA NPPB REN
25 aortic valve disease 2 30.2 ACE MYH7 NPPA NPPB REN
26 hypokalemia 30.1 ACE NR3C2 REN
27 coronary artery anomaly 30.1 ACE ADRB1 AGTR1 EDN1 KNG1 NPPA
28 cerebrovascular disease 30.1 ACE ADM AGTR1 REN
29 systolic heart failure 30.1 ACE ADRB1 NPPB NR3C2
30 renovascular hypertension 30.1 ACE ADM AGTR1 EDN1 NPPA REN
31 left ventricular noncompaction 30.0 AMPD1 MYH6 MYH7
32 heart disease 30.0 ACE ADM ADRB1 ADRB2 AGTR1 EDN1
33 aortic coarctation 30.0 ACE ADRB1 ADRB2 AGTR1 EDN1
34 dilated cardiomyopathy 29.9 ACE ADRB1 ADRB2 AGTR1 EDN1 MYH6
35 myocardial infarction 28.8 ACE ADM ADRB1 ADRB2 AGTR1 EDN1
36 hypertension, essential 27.2 ACE ADM ADRB1 ADRB2 AGTR1 EDN1
37 polycystic kidney disease 4 with or without hepatic disease 11.7
38 rheumatic heart disease 11.5
39 mental retardation, x-linked, syndromic 32 11.3
40 peripartum cardiomyopathy 11.2
41 ventricular septal defect 1 11.1
42 ventricular septal defect 2 11.1
43 ventricular septal defect 3 11.1
44 pleural disease 11.1
45 crimean-congo hemorrhagic fever 11.0
46 cardiomyopathy, dilated, 1a 10.9
47 kyrle disease 10.9
48 mitral valve prolapse 1 10.9
49 pulmonary atresia with ventricular septal defect 10.9
50 cardiomyopathy, familial hypertrophic, 1 10.9

Graphical network of the top 20 diseases related to Congestive Heart Failure:



Diseases related to Congestive Heart Failure

Symptoms & Phenotypes for Congestive Heart Failure

UMLS symptoms related to Congestive Heart Failure:


syncope, edema, equilibration disorder, tremor, chest pain, angina pectoris

MGI Mouse Phenotypes related to Congestive Heart Failure:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.2 VCL MYH6 ADM MYH7 ADRB1 NPPA
2 homeostasis/metabolism MP:0005376 10.13 UTS2 MME MYH6 ADM ADRB1 NPPA
3 mortality/aging MP:0010768 9.97 REN VCL MYH6 ADM ADRB1 NPPC
4 muscle MP:0005369 9.73 VCL MYH6 ADM MYH7 ADRB1 NPPA
5 renal/urinary system MP:0005367 9.17 REN ACE ADM NPPA AGTR1 NR3C2

Drugs & Therapeutics for Congestive Heart Failure

Drugs for Congestive Heart Failure (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 993)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Alogliptin Approved Phase 4 850649-61-5 11450633
2
Linagliptin Approved Phase 4,Phase 3 668270-12-0 10096344
3
Saxagliptin Approved Phase 4,Phase 3 361442-04-8 11243969
4
Vildagliptin Approved, Investigational Phase 4 274901-16-5 6918537
5
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 54-31-9 3440
6
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-93-5 3639
7
Metolazone Approved Phase 4,Phase 2,Phase 1 17560-51-9 4170
8
Dobutamine Approved Phase 4,Phase 3,Phase 2,Phase 1 34368-04-2 36811
9
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-61-6, 62-31-7 681
10
Digoxin Approved Phase 4,Phase 2,Phase 3,Phase 1 20830-75-5 2724385 30322
11
Spironolactone Approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 1952-01-7, 52-01-7 5833
12
Carvedilol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 72956-09-3 2585
13
Verapamil Approved Phase 4,Phase 3 52-53-9 2520
14
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 10102-43-9 145068
15
Nitroprusside Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 15078-28-1 11963622
16
Amiodarone Approved, Investigational Phase 4,Phase 3,Phase 2 1951-25-3 2157
17
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
18
Menthol Approved Phase 4,Phase 2,Phase 1,Early Phase 1 2216-51-5 16666
19
Budesonide Approved Phase 4 51333-22-3 5281004 63006
20
Ipratropium Approved Phase 4,Phase 3 22254-24-6, 60205-81-4 43232
21
Terbutaline Approved Phase 4 23031-25-6 5403
22
Enalapril Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 75847-73-3 40466924 5362032
23
Enalaprilat Approved Phase 4,Phase 2,Phase 3,Phase 1 76420-72-9 6917719
24
Metoprolol Approved, Investigational Phase 4,Phase 3,Phase 2 51384-51-1, 37350-58-6 4171
25
Enfuvirtide Approved, Investigational Phase 4 159519-65-0 16130199
26
Bisoprolol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 66722-44-9 2405
27
Captopril Approved Phase 4,Phase 3,Phase 1,Early Phase 1 62571-86-2 44093
28
Eplerenone Approved Phase 4,Phase 2,Phase 3,Phase 1 107724-20-9 443872 150310
29
Lisinopril Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 83915-83-7, 76547-98-3 5362119
30
Nebivolol Approved, Investigational Phase 4,Phase 2,Phase 3 152520-56-4, 118457-14-0, 99200-09-6 71301
31
Ramipril Approved Phase 4,Phase 3,Phase 2 87333-19-5 5362129
32
Valsartan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137862-53-4 60846
33
Angiotensin II Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
34
Dalteparin Approved Phase 4,Phase 3,Phase 2 9005-49-6
35
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 46507594 772
36
Bivalirudin Approved, Investigational Phase 4,Phase 3 128270-60-0 16129704
37
Tenecteplase Approved Phase 4,Phase 3,Phase 2 191588-94-0
38
Tirofiban Approved Phase 4 144494-65-5 60947
39
Acarbose Approved, Investigational Phase 4,Phase 3 56180-94-0 441184
40
Pravastatin Approved Phase 4,Phase 3 81093-37-0 54687
41
Pioglitazone Approved, Investigational Phase 4,Phase 3,Phase 2 111025-46-8 4829
42
Tadalafil Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 171596-29-5 110635
43
Amlodipine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 88150-42-9 2162
44
Everolimus Approved Phase 4,Phase 3,Phase 1,Phase 2 159351-69-6 6442177
45
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
46
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 53123-88-9 46835353 6436030 5284616
47
Cyclophosphamide Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 50-18-0, 6055-19-2 2907
48
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2 23214-92-8 31703
49
Epirubicin Approved Phase 4,Phase 2 56420-45-2 41867
50
Fluorouracil Approved Phase 4,Phase 2,Phase 1 51-21-8 3385

Interventional clinical trials:

(show top 50) (show all 5175)

# Name Status NCT ID Phase Drugs
1 DPP-4 Inhibitor and Serum BNP Level of Diabetic Patients With Congestive Heart Failure Unknown status NCT02312427 Phase 4 Suspending DPP-4 inhibitor, in outpatient service;Starting DPP-4 inhibitor after treatment of heart failure
2 Evaluation of Sildenafil for the Treatment of Moderate Congestive Heart Failure Unknown status NCT00793338 Phase 4 Sildenafil
3 Long-Term Intermittent Administration of Levosimendan in Patients With Advanced Heart Failure Unknown status NCT00988806 Phase 4 Levosimendan;Placebo
4 Add-on Aliskiren Treatment in Patients With Chronic Congestive Heart Failure Unknown status NCT01040494 Phase 4 Aliskiren;Placebo
5 A Comparison of Hydrochlorothiazide and Metolazone in Combination With Furosemide in Congestive Heart Failure Patients Unknown status NCT00690521 Phase 4 metolazone or hydrochlorothiazide
6 THalidomide on Left ventricUlar Morphology aND Function in congEstive heaRt Failure Unknown status NCT01640639 Phase 4 Thalidomide;Placebo
7 PREVENT-HF: Prevention of Heart Failure Events With Impedance Cardiography Testing Unknown status NCT00409916 Phase 4
8 Outcome and Safety of Intermittent Dobutamine Infusion at a Day-Care Center in Advanced Heart Failure Patients Unknown status NCT01930734 Phase 4 Dobutamine;Normal Saline
9 Dopamine in Acute Decompensated Heart Failure (DAD-HF) Trial Unknown status NCT00937092 Phase 4 Furosemide;low-dose dopamine + low-dose furosemide
10 A Strategy of Home Telehealth for Management of Congestive Heart Failure(STARTEL) Unknown status NCT00247000 Phase 4
11 Digoxin Versus Ivabradine in Heart Failure With Reduced Ejection Fraction Unknown status NCT02046044 Phase 4 Digoxin;Ivabradine
12 Improvement of Patients With Chronic Heart Failure Using NT-proBNP Unknown status NCT00601679 Phase 4
13 Quadripolar Leads for the Management of Heart Failure Patients in the Middle East Unknown status NCT02195843 Phase 4
14 Effects of Levothyroxine Supplementation in Patients With Systolic Heart Failure and Subclinical Hypothyroidism Unknown status NCT02316743 Phase 4 Levothyroxine supplementation
15 Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure Unknown status NCT00527059 Phase 4 Levosimendan in addition to standard therapy;spironolactone, beta-blockers,ecc
16 Effects of Atrial Rate-adaptive Pacing on Exercise Capacity in Patients With Chronic Heart Failure Complicated by Chronotropic Incompetence Unknown status NCT01016431 Phase 4
17 Carvedilol Versus Verapamil in Chronic Heart Failure Secondary to Non-Ischemic Cardiomyopathy Unknown status NCT00348530 Phase 4 Verapamil
18 Significance of Regional Ventriculo-arterial Coupling in Patients With Chronic Heart Failure Unknown status NCT01156207 Phase 4 Aliskiren
19 VAccination to Improve Clinical outComes in Heart Failure Trial: a Feasibility Study (VACC-HeFT) Unknown status NCT02268500 Phase 4
20 Investigator Initiated Randomized Open-label Comparative Study of Britomar (Prolonged Release Torasemide) and Diuver (Torasemide) to Assess Effects on Natriuresis and Central Hemodynamics. Unknown status NCT02087332 Phase 4 Prolonged release Torasemide (Britomar);Torasemide (Diuver)
21 Intravenous Vasodilator vs. Inotropic Therapy in Patients With Heart Failure Reduced Ejection Fraction and Acute Decompensation With Low Cardiac Output (PRIORITY-ADHF Study) Unknown status NCT02767024 Phase 4 Sodium nitroprusside;Dobutamine;Furosemide
22 Therapy With Verapamil or Carvedilol in Chronic Heart Failure Unknown status NCT00374465 Phase 4 Verapamil;Carvedilol
23 Shensong Yangxin Capsule in the Treatment of Heart Failure Complicated With Ventricular Premature Beat Unknown status NCT01612260 Phase 4 Shensong Yangxin capsule;placebo Capsule
24 N-3 Fatty Acids for the Prevention of Atrial Fibrillation in Patients With Acute Heart Failure Unknown status NCT00692718 Phase 4 Epadel, Eicosapentaenoic acid
25 Danish ICD Study in Patients With Dilated Cardiomyopathy Unknown status NCT00542945 Phase 4
26 CARE-HF LTFU: CArdiac REsynchronization in Heart Failure Long-Term Follow-up Unknown status NCT00318357 Phase 4
27 Resynchronization in Paced Heart Failure Patients With Implantable Cardioverter Defibrillator (ICD) Indication Unknown status NCT01415024 Phase 4
28 Treatment of Cheyne Stocks Respiration With Adaptive Servo Ventilation and Bilevel Ventilators in Patients With Chronic Heart Failure Unknown status NCT00725595 Phase 4
29 Cardiac Resynchronization in Atrial Fibrillation Trial - a Pilot Study Unknown status NCT01850277 Phase 4 Amiodarone;Pharmacotherapy to slow and control ventricular rate
30 Body Composition Measurements in Chronic Heart Failure Unknown status NCT02686866 Phase 4
31 LTOT in COPD Patients With Moderate Chronic Hypoxemia and Chronic Heart Failure Unknown status NCT00668408 Phase 4
32 St. Vincent's Screening To Prevent Heart Failure Study Unknown status NCT00921960 Phase 4
33 Atrial Fibrillation Ablation Compared to Rate Control Strategy in Patients With Impaired Left Ventricular Function Unknown status NCT02509754 Phase 4
34 Anti-Hypertensive Agent (ACEi) and Heart Function Improvement in Association With Rho Kinase Activity Changes in Human Unknown status NCT01069042 Phase 4 Enalapril
35 The Angiotensin Converting Enzyme (ACE) Inhibitor SwitchBack Study Unknown status NCT01162980 Phase 4
36 Surgical Treatment of Ischemic Mitral Regurgitation Unknown status NCT01368575 Phase 4
37 Ability of Metoprolol to Alter the Exercise Induced Elevation of Catecholamines Unknown status NCT00885651 Phase 4 Metoprolole (Selo-Zok ®);Placebo
38 Effects of Atorvastatin Treatment on Left Ventricular Diastolic Function in Peritoneal Dialysis Patients Unknown status NCT01503671 Phase 4 Atorvastatin
39 Latin America Cardiac Resynchronization Therapy Study Unknown status NCT01238874 Phase 4
40 Ivabradine in Patients With an Unsatisfactory Percentage of Cardiac Resynchronization Therapy Unknown status NCT02166060 Phase 4 Ivabradine
41 Mode Evaluation in Sick Sinus Syndrome Trial (MODEST) Unknown status NCT00161551 Phase 4
42 Ventricular Pacing Site Selection (V-PASS) Unknown status NCT00292383 Phase 4
43 Study Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise Capacity Unknown status NCT00326690 Phase 4
44 Systematic Withdrawal of Neurohumoral Blocker Therapy in Optimally Responding CRT Patients Unknown status NCT02200822 Phase 4 beta blockers;RAAS blockers
45 Revascularization in Heart Failure Trial – REHEAT 2 Unknown status NCT00388245 Phase 4
46 Erythropoietin Treatment in Patients With Systolic Left Ventricular Dysfunction, Mild Anemia and Normal Renal Function Unknown status NCT00418119 Phase 4 erythropoietin
47 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4 valsartan
48 Changes of Left Ventricular Mass and Cardiac Function in Patients With Active Acromegaly During Treatment With the Growth Hormone Receptor Antagonist Pegvisomant Unknown status NCT00552851 Phase 4 pegvisomant
49 Comparison of Thrombgolytic and Anticoagulation Therapy in Submassive Pulmonary Embolism Unknown status NCT02132689 Phase 4 Actilyse (Thrombolytic therapy);Heparine (Standard anticoagulation therapy)
50 Effect of Conditioning on Myocardial Damage in STEMI Unknown status NCT02158468 Phase 4

Search NIH Clinical Center for Congestive Heart Failure

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Congestive Heart Failure cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Congestive Heart Failure:
ACP-01, autologous angiogenic precursor cells for cardiac diseases
Adipose-derived stem cells for treatment of congestive heart failure
BMAC
Bone marrow-derived adult mononuclear cells for heart diseases
Cardiac progenitor cells for single-ventricle anomalies
Cardiosphere-derived autologous stem cells for reverse ventricular dysfunction
C-Cure
CD133+ bone marrow-derived stem cells in conjuction with coronary artery bypass grafting
CD34+ stem cells for treatment of congestive heart failure
Enriched bone marrow-derived progenitor cells for heart diseases
ERCs, endometrial regenerative cells for congestive heart failure
Human cardiac-derived stem cell for the treatment of congestive heart failure
itMSC, bone marrow-derived mesenchymal stem cells for cardiovascular diseases
Mesenchymal precursor cells for cardiovascular diseases
MyoCell
Peripheral or bone marrow-derived stem cells for chronic heart failure
Embryonic/Adult Cultured Cells Related to Congestive Heart Failure:
Angiogenic cell precursors
Adipose-derived mesenchymal stem cells (family)
Bone Marrow Aspirate Concentrated Nucleated Cells (BMAC) PMIDs: 15995108 23788089 18351022
Bone marrow-derived mononuclear cells PMIDs: 22137069 19699857 20445812 20524773
Cardiac stem cells PMIDs: 18754813 17502484 14530411
Cardiac progenitor cells PMIDs: 18754813 17502484 14530411
Cardiosphere-derived cells PMIDs: 22336189
Cardiomyocyte-like cells PMIDs: 23583247 18835562
Bone marrow-derived CD133+ cells PMIDs: 17320570
Bone marrow-derived hematopoietic stem cells (family) PMIDs: 22163120
Bone marrow-derived progenitor cells PMIDs: 23362308 22936827 18794392 16990384 16990385 22651868
Endometrial regenerative cells PMIDs: 18005405 23510656 20398245 19232091
Human cardiac stem cells PMIDs: 17502484 19038683 17150190
Mesenchymal Precursor Cells (STRO-3 selected) PMIDs: 20850099 21155976
Skeletal myoblasts (MyoCell PMIDs: 19051139 15615560 16446778
Bone marrow-derived mononuclear cells PMIDs: 20668107 21596713 19761394 22834565

Cochrane evidence based reviews: heart failure

Genetic Tests for Congestive Heart Failure

Genetic tests related to Congestive Heart Failure:

# Genetic test Affiliating Genes
1 Congestive Heart Failure 28

Anatomical Context for Congestive Heart Failure

MalaCards organs/tissues related to Congestive Heart Failure:

38
Heart, Kidney, Breast, Lung, Bone, Testes, Endothelial
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Congestive Heart Failure:
# Tissue Anatomical CompartmentCell Relevance
1 Adipose Subcutaneous White Adipose Mesenchymal Stem Cells Potential therapeutic candidate
2 Lateral Plate Mesoderm Splanchnic Mesoderm Pericytes Potential therapeutic candidate
3 Adipose Subcutaneous White Adipose Stromal Cells Potential therapeutic candidate

Publications for Congestive Heart Failure

Articles related to Congestive Heart Failure:

(show top 50) (show all 1409)
# Title Authors Year
1
Dietary Sodium Interventions to Prevent Hospitalization and Readmission in Adults with Congestive Heart Failure. ( 29307539 )
2018
2
Percutaneous Occlusion of Patent Ductus Arteriosus for an Elderly Patient With Refractory Congestive Heart Failure. ( 29367269 )
2018
3
White blood cell differentials in dogs with congestive heart failure (CHF) in comparison to those in dogs without cardiac disease. ( 29314019 )
2018
4
Genome-wide sequencing and quantification of circulating microRNAs for dogs with congestive heart failure secondary to myxomatous mitral valve degeneration. ( 29359980 )
2018
5
Myocardial oedema and congestive heart failure: one piece of the puzzle? Reply. ( 29319924 )
2018
6
Usefulness of a Telemedicine Program in Refractory Older Congestive Heart Failure Patients. ( 29361704 )
2018
7
Oscillatory behavior of P wave duration and PR interval in experimental congestive heart failure: a preliminary study. ( 29393857 )
2018
8
Increased risk of congestive heart failure in patients with acetaminophen poisoning: A nationwide cohort study. ( 29327353 )
2018
9
Factors associated with health-related quality of life in stable ambulatory congestive heart failure patients: Systematic review. ( 29384392 )
2018
10
Myocardial oedema and congestive heart failure: one piece of the puzzle? ( 29327803 )
2018
11
Associations between ambient air pollution and daily mortality in a cohort of congestive heart failure: Case-crossover and nested case-control analyses using a distributed lag nonlinear model. ( 29361317 )
2018
12
A New Secretory Peptide of Natriuretic Peptide Family, Osteocrin, Suppresses the Progression of Congestive Heart Failure After Myocardial Infarction. ( 29326144 )
2018
13
Determining the role of intravenous hydration on hospital readmissions for acute congestive heart failure. ( 29383227 )
2018
14
It's Time to Talk: Challenges in Providing Integrated Palliative Care in Advanced Congestive Heart Failure. ( 29366424 )
2018
15
Clinical Outcomes of Metformin Use in Populations With Chronic Kidney Disease, Congestive Heart Failure, or Chronic Liver Disease: A Systematic Review. ( 28055049 )
2017
16
Investigation of the link between fluid shift and airway collapsibility as a mechanism for obstructive sleep apnea in congestive heart failure. ( 28057850 )
2017
17
Gender-adjusted and age-adjusted economic inpatient burden of congestive heart failure: cost and disability-adjusted life-year analysis. ( 28772046 )
2017
18
Central Sleep Apnea in Patients with Congestive Heart Failure. ( 28477776 )
2017
19
Effects and safety of oral tolvaptan in patients with congestive heart failure: A systematic review and network meta-analysis. ( 28898297 )
2017
20
The evaluation of I^-adrenoceptor blocking agents in patients with COPD and congestive heart failure: a nationwide study. ( 28894360 )
2017
21
Risk factors for 30-day readmission in patients with congestive heart failure. ( 28801110 )
2017
22
Sleep-Disordered Breathing During Congestive Heart Failure: To Intervene or Not to Intervene? ( 29387467 )
2017
23
A Case of Fulminant Hepatic Failure Secondary to Congestive Heart Failure Without Evidence of Acute Cardiac Decompensation. ( 28813731 )
2017
24
Processes and Outcomes of Congestive Heart Failure Care by Different Types of Primary Care Models. ( 28870732 )
2017
25
Prognostic Value of Different Allelic Polymorphism of Aldosterone Synthase Receptor in a Congestive Heart Failure European Continental Ancestry Population. ( 28625318 )
2017
26
Impact of right ventricular distensibility on congestive heart failure with preserved left ventricular ejection fraction in the elderly. ( 29234860 )
2017
27
Veterans' Voice Through the Lens of Their Medical Records: What It Reveals About Congestive Heart Failure Readmissions. ( 27902575 )
2017
28
Diffuse neonatal hemangiomatosis presenting as congestive heart failure. ( 29085724 )
2017
29
Poor acute outcome in congestive heart failure is associated with increases in the plasma static oxidation-reduction potentials (sORP) in men but not in women. ( 28845739 )
2017
30
Association Between C1q/TNF-Related Protein-1 Levels in Human Plasma and Epicardial Adipose Tissues and Congestive Heart Failure. ( 28810263 )
2017
31
Long Noncoding RNA Kcna2 Antisense RNA Contributes to Ventricular Arrhythmias via Silencing Kcna2 in Rats With Congestive Heart Failure. ( 29263036 )
2017
32
Congestive Heart Failure During Osimertinib Treatment for Epidermal Growth Factor Receptor (EGFR)-mutant Non-small Cell Lung Cancer (NSCLC). ( 28781309 )
2017
33
Use of Wavelet Transform to Detect Compensated and Decompensated Stages in the Congestive Heart Failure Patient. ( 28930184 )
2017
34
Risk of stroke in congestive heart failure with and without atrial fibrillation. ( 28826798 )
2017
35
In-hospital and long-term outcomes of congestive heart failure: Predictive value of B-type and amino-terminal pro-B-type natriuretic peptides and their ratio. ( 28810640 )
2017
36
Frequency and number of B-lines using a regionally based lung ultrasound examination in cats with radiographically normal lungs compared to cats with left-sided congestive heart failure. ( 28763158 )
2017
37
Unusual cardiac involvement in granulomatosis with polyangiitis manifesting as acute congestive heart failure. ( 28766511 )
2017
38
The NF-kB regulates the SHP-1 expression in monocytes in congestive heart failure. ( 27814644 )
2017
39
Pathological alterations in liver injury following congestive heart failure induced by volume overload in rats. ( 28934226 )
2017
40
High-Intensity Training Improves Global and Segmental Strains in Severe Congestive Heart Failure. ( 28069473 )
2017
41
Diffuse alveolar haemorrhage with predominant upper lung lobe involvement associated with congestive heart failure: a case series. ( 29268406 )
2017
42
Chewable tablets for congestive heart failure in dogs. ( 28883117 )
2017
43
The SEISICAT study: a pilot study assessing efficacy and safety of spironolactone in cats with congestive heart failure secondary to cardiomyopathy. ( 29277469 )
2017
44
Congestive Heart Failure with Preserved Ejection Fraction in a Patient with Light Chain (AL) Amyloidosis and Multiple Myeloma. ( 28701686 )
2017
45
Use of Biomarkers to Predict Readmission for Congestive Heart Failure. ( 27939586 )
2017
46
Kyoto Congestive Heart Failure (KCHF) study: rationale and design. ( 28772047 )
2017
47
Epidemiological profile and obstetric outcomes of patients with peripartum congestive heart failure in Taiwan: a retrospective nationwide study. ( 28899350 )
2017
48
Chilaiditi syndrome mimicking congestive heart failure. ( 28710199 )
2017
49
Serum C-Reactive Protein and Congestive Heart Failure as Significant Predictors of Herpes Zoster Vaccine Response in Elderly Nursing Home Residents. ( 28838148 )
2017
50
Correction to: Good response to tolvaptan shortens hospitalization in patients with congestive heart failure. ( 29234859 )
2017

Variations for Congestive Heart Failure

ClinVar genetic disease variations for Congestive Heart Failure:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 PSEN1 NM_000021.3(PSEN1): c.998A> G (p.Asp333Gly) single nucleotide variant Pathogenic/Likely pathogenic rs121917809 GRCh37 Chromosome 14, 73678519: 73678519

Expression for Congestive Heart Failure

Search GEO for disease gene expression data for Congestive Heart Failure.

Pathways for Congestive Heart Failure

Pathways related to Congestive Heart Failure according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.6 MYH6 NPPA NPPC NPR1 VCL
2
Show member pathways
12.52 ADRB1 ADRB2 AGTR1 MYH6 MYH7 NPR1
3
Show member pathways
12.44 ADRB1 ADRB2 AGTR1 MYH7 NPPB NPR1
4
Show member pathways
11.94 ACE ADRB1 MYH6 MYH7
5 11.67 EDN1 EPO NPPA
6 11.45 ADM EDN1 EPO
7 11.34 ADRB1 ADRB2 NPR1
8
Show member pathways
11.34 ACE AGTR1 KNG1 MME NR3C2 REN
9 10.91 ACE ADRB1 ADRB2 AGTR1 NPR1 REN
10 10.79 ADM ADRB1 ADRB2
11 10.67 MYH7 NPPA NPPB

GO Terms for Congestive Heart Failure

Cellular components related to Congestive Heart Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 ACE ADM EDN1 EPO KNG1 NPPA
2 extracellular space GO:0005615 9.32 ACE ADM EDN1 EPO KNG1 NPPA
3 myosin filament GO:0032982 9.16 MYH6 MYH7

Biological processes related to Congestive Heart Failure according to GeneCards Suite gene sharing:

(show all 38)
# Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 9.97 ADRB2 EDN1 NPPB NPR1
2 response to lipopolysaccharide GO:0032496 9.93 ADM EDN1 EPO REN
3 positive regulation of cytosolic calcium ion concentration GO:0007204 9.91 ADM AGTR1 EDN1 KNG1
4 response to hypoxia GO:0001666 9.91 ADM EDN1 EPO NPPA NPPC
5 regulation of receptor activity GO:0010469 9.91 ADM EDN1 EPO NPPA NPPB NPPC
6 muscle contraction GO:0006936 9.88 MYH6 MYH7 UTS2 VCL
7 kidney development GO:0001822 9.87 ACE AGTR1 MME REN
8 response to organic substance GO:0010033 9.84 ADM AMPD1 REN
9 adenylate cyclase-activating G-protein coupled receptor signaling pathway GO:0007189 9.81 ADM ADRB1 ADRB2
10 regulation of cardiac conduction GO:1903779 9.8 NPPA NPPC NPR1
11 response to cold GO:0009409 9.79 ADM ADRB1 ADRB2
12 regulation of vasoconstriction GO:0019229 9.73 ACE AGTR1 EDN1
13 positive regulation of heart rate GO:0010460 9.72 ADM EDN1 NPPA
14 regulation of the force of heart contraction GO:0002026 9.71 ADM MYH6 MYH7
15 cardiac muscle hypertrophy in response to stress GO:0014898 9.7 MYH6 MYH7 NPPA
16 response to muscle stretch GO:0035994 9.68 EDN1 NPPA
17 negative regulation of blood coagulation GO:0030195 9.67 EDN1 KNG1
18 adult heart development GO:0007512 9.67 MYH6 MYH7
19 amyloid-beta metabolic process GO:0050435 9.67 ACE MME REN
20 response to dexamethasone GO:0071548 9.66 EDN1 EPO
21 negative regulation of multicellular organism growth GO:0040015 9.65 ADRB1 ADRB2
22 positive regulation of cGMP biosynthetic process GO:0030828 9.65 NPPC NPR1
23 regulation of vascular permeability GO:0043114 9.65 NPPB NPR1
24 positive regulation of renal sodium excretion GO:0035815 9.65 EDN1 NPPB NPR1
25 diet induced thermogenesis GO:0002024 9.64 ADRB1 ADRB2
26 positive regulation of urine volume GO:0035810 9.63 EDN1 NPPB NPR1
27 regulation of blood vessel size GO:0050880 9.63 EDN1 KNG1 NPPA NPPB NPPC NPR1
28 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.62 ACE AGTR1
29 cGMP biosynthetic process GO:0006182 9.62 NPPA NPPB NPPC NPR1
30 renin-angiotensin regulation of aldosterone production GO:0002018 9.61 AGTR1 REN
31 angiotensin maturation GO:0002003 9.61 ACE MME REN
32 heat generation GO:0031649 9.6 ADRB1 ADRB2
33 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure GO:0002025 9.59 ADRB1 ADRB2
34 body fluid secretion GO:0007589 9.58 EDN1 NPPB NPR1
35 receptor guanylyl cyclase signaling pathway GO:0007168 9.56 NPPA NPPB NPPC NPR1
36 regulation of blood vessel diameter GO:0097746 9.43 ACE ADRB2 AGTR1 NPPB NPR1 UTS2
37 regulation of blood pressure GO:0008217 9.23 ACE EDN1 MYH6 NPPA NPPB NPR1
38 G-protein coupled receptor signaling pathway GO:0007186 10.19 ADM ADRB1 ADRB2 AGTR1 EDN1 KNG1

Molecular functions related to Congestive Heart Failure according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 endopeptidase activity GO:0004175 9.63 ACE MME REN
2 receptor binding GO:0005102 9.56 ADM