MCID: CNS002
MIFTS: 37

Constrictive Pericarditis

Categories: Cardiovascular diseases

Aliases & Classifications for Constrictive Pericarditis

MalaCards integrated aliases for Constrictive Pericarditis:

Name: Constrictive Pericarditis 12 14
Pericarditis, Constrictive 41 69
Constrictive Pericarditis Nos 12
Pericarditis Constrictive 51

Classifications:



External Ids:

Disease Ontology 12 DOID:11481
ICD9CM 34 423.2
MeSH 41 D010494
NCIt 46 C78246
UMLS 69 C0031048

Summaries for Constrictive Pericarditis

MalaCards based summary : Constrictive Pericarditis, also known as pericarditis, constrictive, is related to pericarditis and pericardial effusion. An important gene associated with Constrictive Pericarditis is NPPB (Natriuretic Peptide B). The drugs Coal tar and Colchicine have been mentioned in the context of this disorder. Affiliated tissues include heart, liver and lung.

Wikipedia : 72 Constrictive pericarditis is a medical condition characterized by a thickened, fibrotic pericardium,... more...

Related Diseases for Constrictive Pericarditis

Diseases related to Constrictive Pericarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 145)
# Related Disease Score Top Affiliating Genes
1 pericarditis 31.6 ADA NPPB PRG4
2 pericardial effusion 30.8 ADA NPPB
3 protein-losing enteropathy 30.1 ALB SERPINA1
4 arteries, anomalies of 29.7 ALB NPPB
5 peritonitis 29.4 ADA ALB
6 mulibrey nanism 11.6
7 restrictive cardiomyopathy 10.6
8 hemopericardium 10.4
9 ascites, chylous 10.2
10 rheumatoid arthritis 10.2
11 mycobacterium tuberculosis 1 10.2
12 arthritis 10.2
13 cardiac tamponade 10.2
14 pericardial mesothelioma 10.2
15 aneurysm 10.2
16 myocardial infarction 10.1
17 lymphoma 10.1
18 viral meningitis 10.1 ADA SERPINA1
19 fibrosis of extraocular muscles, congenital, 1 10.1
20 ventricular septal defect 10.1
21 atrial heart septal defect 10.1
22 amyloidosis 10.1
23 synovitis 10.0 IL1RN PRG4
24 histidine metabolism disease 10.0 SERPINA1 TRIM37
25 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 10.0
26 hydrops, lactic acidosis, and sideroblastic anemia 10.0
27 coronary artery anomaly 10.0
28 hepatitis 10.0
29 atrial fibrillation 10.0
30 thrombosis 10.0
31 heart disease 10.0
32 hypertrophic cardiomyopathy 10.0
33 porphyria 10.0
34 mediastinitis 10.0
35 diastolic heart failure 10.0
36 syncope 10.0
37 syndrome of inappropriate antidiuretic hormone 10.0 ALB NPPB
38 histidinemia 10.0 SERPINA1 TRIM37
39 tricuspid valve insufficiency 10.0 ALB NPPB
40 gastrointestinal tuberculosis 10.0 ADA ALB
41 abdominal tuberculosis 10.0 ADA ALB
42 renal hypertension 10.0 ALB NPPB
43 tuberculous peritonitis 10.0 ADA ALB
44 omenn syndrome 9.9 ADA IL1RN
45 pleural disease 9.9 ADA ALB
46 pulmonary embolism 9.9 ALB NPPB
47 pick disease of brain 9.9
48 porphyria cutanea tarda 9.9
49 tetralogy of fallot 9.9
50 thrombophilia due to thrombin defect 9.9

Comorbidity relations with Constrictive Pericarditis via Phenotypic Disease Network (PDN):


Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Intermediate Coronary Syndrome
Ischemic Heart Disease Mitral Valve Disease

Graphical network of the top 20 diseases related to Constrictive Pericarditis:



Diseases related to Constrictive Pericarditis

Symptoms & Phenotypes for Constrictive Pericarditis

Drugs & Therapeutics for Constrictive Pericarditis

Drugs for Constrictive Pericarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Coal tar Approved Phase 4,Phase 3 8007-45-2
2
Colchicine Approved Phase 4,Phase 3 64-86-8 2833 6167
3 Antimitotic Agents Phase 4,Phase 3
4 Antirheumatic Agents Phase 4,Phase 3
5 Fibrinolytic Agents Phase 3
6 Plasminogen Phase 3
7 Tissue Plasminogen Activator Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of Colchicine to Treat and Prevent Recurrent Pericarditis After Failure of Conventional Treatment. Completed NCT00235079 Phase 4 Colchicine;Placebo
2 Study of Colchicine to Prevent the Postpericardiotomy Syndrome Completed NCT00128427 Phase 3 Colchicine (for 1 month)
3 Study of Colchicine to Treat and Prevent Recurrent Pericarditis (First Episode) Completed NCT00128414 Phase 3 Colchicine (for 6 months);Placebo
4 Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences Completed NCT00128453 Phase 3 Colchicine (for 3 months);Placebo
5 IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion Recruiting NCT02673879 Phase 3
6 Septal Shift for the Diagnosis of COnstrictive Pericarditis: The Impact of Inspiratory Effort Quantification on Deep Breathing Manoeuvres Unknown status NCT02685371
7 Prognostic Biomarkers in Patients With Acute Pericarditis Recruiting NCT02754713
8 Management of Pericarditis in Children. Not yet recruiting NCT03253315
9 Constrictive Pericarditis in the Adult Congenital Cardiac Population Terminated NCT00268086
10 New Methods to Diagnose Constrictive Pericarditis Withdrawn NCT02027350

Search NIH Clinical Center for Constrictive Pericarditis

Cochrane evidence based reviews: pericarditis, constrictive

Genetic Tests for Constrictive Pericarditis

Anatomical Context for Constrictive Pericarditis

MalaCards organs/tissues related to Constrictive Pericarditis:

38
Heart, Liver, Lung, Bone, B Cells, Bone Marrow, Brain

Publications for Constrictive Pericarditis

Articles related to Constrictive Pericarditis:

(show top 50) (show all 691)
# Title Authors Year
1
Constrictive Pericarditis as a Long-term Undetermined Etiology of Ascites and Edema. ( 29321423 )
2018
2
Implantable epicardial cardioverter-defibrillator-induced localized constrictive pericarditis. ( 29049636 )
2018
3
Clinical features, management and outcome of patients with constrictive pericarditis - Experience from a third world country. ( 29296059 )
2018
4
Pericardiectomy for Constrictive Pericarditis: An Institution's 21 Years Experience. ( 28780766 )
2017
5
A case report of combined radical pericardiectomy and beating heart coronary artery bypass grafting in a patient with tubercular chronic constrictive pericarditis with coronary artery disease. ( 28994689 )
2017
6
Constrictive pericarditis from an endocardial pacemaker lead. ( 28710300 )
2017
7
Pericardial interstitial cell senescence responsible for pericardial structural remodeling in idiopathic and postsurgical constrictive pericarditis. ( 28456362 )
2017
8
Constrictive pericarditis-induced shunting through a PFO: Persistence despite pericardiectomy. ( 28649486 )
2017
9
A mysterious cause of constrictive pericarditis: unfolding of the missing link. ( 29293944 )
2017
10
Constrictive pericarditis caused by Cutibacterium (Propionibacterium) acnes: A case report and review of literature. ( 29021959 )
2017
11
Constrictive Pericarditis ( 29083701 )
2017
12
Effectiveness and long-term outcomes of surgical intervention for constrictive epicardium in constrictive pericarditis. ( 29080093 )
2017
13
Constrictive Pericarditis 5 Months after Radiation Therapy in a 62-Year-Old Woman with Esophageal Cancer. ( 29276442 )
2017
14
Purulent constrictive pericarditis caused by Salmonella enteritidis in a patient with adult-onset Still's disease: A case report. ( 29390286 )
2017
15
Importance of Clinical and Laboratory Findings in the Diagnosis and Surgical Prognosis of Patients with Constrictive Pericarditis. ( 28977057 )
2017
16
Transitory effusive-constrictive pericarditis. ( 29169889 )
2017
17
Constrictive Pericarditis: A Practical Clinical Approach. ( 28062267 )
2017
18
Constrictive Pericarditis. ( 29025545 )
2017
19
Uremic pericarditis, pericardial effusion, and constrictive pericarditis in end-stage renal disease: Insights and pathophysiology. ( 28873222 )
2017
20
Effusive-Constrictive Pericarditis. ( 29025546 )
2017
21
A Rare Case of Pneumopericardium in the Setting of Tuberculous Constrictive Pericarditis. ( 28634555 )
2017
22
New Cardiac Imaging Algorithms to Diagnose Constrictive Pericarditis Versus Restrictive Cardiomyopathy. ( 28405937 )
2017
23
Surgical Treatment of Constrictive Pericarditis. ( 28461794 )
2017
24
Constrictive pericarditis: diagnosis, management and clinical outcomes. ( 29175978 )
2017
25
Effusive constrictive pericarditis diagnosed with PET/CT and treated medically. ( 29256890 )
2017
26
A Case of Severe Adult-onset Still Disease with Constrictive pericarditis and Pleuritis that Was Successfully Treated with Tocilizumab in Addition to Corticosteroids and Cyclosporin A. ( 29269680 )
2017
27
Progressive Constrictive Pericarditis Shortly after Purulent Pericarditis. ( 29021457 )
2017
28
Experience With Pericardiectomy for Constrictive Pericarditis Over Eight Decades. ( 28760468 )
2017
29
Restrictive Cardiomyopathy or Constrictive Pericarditis: An Unresolved Conundrum. ( 29187041 )
2017
30
Chylous Ascites and Chylothorax Caused by Constrictive Pericarditis. ( 29052575 )
2017
31
Serial semi-invasive hemodynamic assessment following pericardiectomy for chronic constrictive pericarditis. ( 28393776 )
2017
32
Effusive-Constrictive Pericarditis After Pericardiocentesis: Incidence, Associated Findings, and Natural History. ( 28917680 )
2017
33
Localized constrictive pericarditis compressing and obstructing the right ventricular inflow tract due to a giant anterior calcified cardiac mass. A case report. ( 28886389 )
2017
34
Visualization of suppressed intraventricular flow by constrictive pericarditis. ( 28800477 )
2017
35
Transient constrictive pericarditis following acute idiopathic pericarditis. AA case report. ( 28827145 )
2017
36
A clinical enigma of ongoing constrictive pericarditis. ( 28572226 )
2017
37
Major vessel venous thrombosis in patients of posttubercular chronic constrictive pericarditis undergoing pericardectomy: A rare scenario. ( 28701604 )
2017
38
Large ventricular septal defect and coexisting chronic constrictive pericarditis: "reversible Eisenmenger syndrome"-5 years after corrective surgery. ( 28303664 )
2017
39
Multidrug Resistant Invasive Nontyphoidal Salmonella Isolated from and Masquerading Healed Tubercular Constrictive Pericarditis and Study of Virulence Markers. ( 28560124 )
2017
40
Right-Sided Heart Failure and Extracorporeal Life Support in Patients Undergoing Pericardiectomy for Constrictive Pericarditis: A Risk Factor Analysis for Adverse Outcome. ( 27855469 )
2016
41
Ascites: it is not all alcohol-a case of constrictive pericarditis. ( 27758795 )
2016
42
Late presentation of constrictive pericarditis after limited epicardial ablation for inappropriate sinus tachycardia. ( 28491729 )
2016
43
Long-Term Effects of Pericardiectomy on Left Ventricular Mechanics Evaluated by Using Speckle Tracking Echocardiography in Patients with Constrictive Pericarditis. ( 26653938 )
2016
44
Sticking points in magnetic resonance diagnosis of constrictive pericarditis. ( 27085615 )
2016
45
Constrictive Pericarditis and Protein-Losing Enteropathy: Is Extremely Severe Hypoalbuminemia Reversible by Pericardiectomy? ( 27864304 )
2016
46
Long-Term Clinical Outcomes and Prognostic Factors After Pericardiectomy for Constrictive Pericarditis in a Japanese Population. ( 27928144 )
2016
47
Effect of Right Heart Systolic Function on Outcomes in Patients with Constrictive Pericarditis Undergoing Pericardiectomy. ( 26830985 )
2016
48
IgG4-related effusive constrictive pericarditis. ( 27044912 )
2016
49
Transient Constrictive Pericarditis: Current Diagnostic and Therapeutic Strategies. ( 26995404 )
2016
50
Constrictive pericarditis following open-heart surgery in a child. ( 27011697 )
2016

Variations for Constrictive Pericarditis

Expression for Constrictive Pericarditis

Search GEO for disease gene expression data for Constrictive Pericarditis.

Pathways for Constrictive Pericarditis

GO Terms for Constrictive Pericarditis

Cellular components related to Constrictive Pericarditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.55 ALB IL1RN NPPB PRG4 SERPINA1
2 extracellular space GO:0005615 9.02 ADA ALB IL1RN NPPB SERPINA1
3 platelet alpha granule lumen GO:0031093 8.96 ALB SERPINA1

Sources for Constrictive Pericarditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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