Aliases & Classifications for Corneal Disease

MalaCards integrated aliases for Corneal Disease:

Name: Corneal Disease 12 14
Corneal Diseases 51 41 69
Corneal Disorders 40

Classifications:



External Ids:

Disease Ontology 12 DOID:10124
ICD10 32 H18.9 H17.9
ICD9CM 34 371.9
MeSH 41 D003316
NCIt 46 C26731
UMLS 69 C0010034

Summaries for Corneal Disease

MedlinePlus : 40 Your cornea is the outermost layer of your eye. It is clear and shaped like a dome. The cornea helps to shield the rest of the eye from germs, dust, and other harmful matter. It also helps your eye to focus. If you wear contact lenses, they float on top of your corneas. Problems with the cornea include Refractive errors Allergies Infections Injuries Dystrophies - conditions in which parts of the cornea lose clarity due to a buildup of cloudy material Treatments of corneal disorders include medicines, corneal transplantation, and corneal laser surgery. NIH: National Eye Institute

MalaCards based summary : Corneal Disease, also known as corneal diseases, is related to keratitis, hereditary and corneal dystrophy, meesmann, and has symptoms including eye manifestations An important gene associated with Corneal Disease is TGFBI (Transforming Growth Factor Beta Induced), and among its related pathways/superpathways is Hypertrophy Model. The drugs Epinephrine and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and skin, and related phenotypes are homeostasis/metabolism and immune system

Related Diseases for Corneal Disease

Diseases related to Corneal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 71)
# Related Disease Score Top Affiliating Genes
1 keratitis, hereditary 31.9 GJB2 GJB6 TLR9
2 corneal dystrophy, meesmann 31.4 CHST6 COL8A2 KRT12 KRT3 TGFBI
3 corneal dystrophy, posterior polymorphous, 1 31.4 COL8A2 SLC4A11 VSX1 ZEB1
4 corneal dystrophy, avellino type 31.3 CHST6 TGFBI
5 keratoconus 30.6 COL8A2 GSN IL1A KERA KRT12 KRT3
6 limbal stem cell deficiency 30.3 IL1A KRT12 KRT3
7 kid syndrome 30.1 GJB2 GJB6
8 keratoconjunctivitis sicca 29.9 IL1A NGF TLR9
9 corneal dystrophy, fuchs endothelial, 1 10.7
10 megalocornea 10.7
11 peters-plus syndrome 10.7
12 corneal dystrophy, fuchs endothelial, 4 10.7
13 corneal dystrophy, fuchs endothelial, 6 10.7
14 corneal dystrophy, fuchs endothelial, 8 10.7
15 sclerocornea 10.7
16 corneal dystrophy and perceptive deafness 10.6
17 corneal dystrophy, fuchs endothelial, 2 10.6
18 corneal dystrophy, fuchs endothelial, 3 10.6
19 corneal dystrophy, lattice type i 10.5 GSN TGFBI
20 corneal dystrophy, endothelial, x-linked 10.5 SLC4A11 VSX1
21 deafness, autosomal recessive 1b 10.5 GJB2 GJB6
22 deafness, autosomal dominant 24 10.4 GJB2 GJB6
23 epithelial basement membrane dystrophy 10.4 COL8A2 IL1A TGFBI
24 algoneurodystrophy 10.4 LCAT NGF
25 deafness, x-linked 2 10.4 GJB2 GJB6
26 pseudoainhum 10.4 GJB2 GJB6
27 knuckle pads, leukonychia, and sensorineural deafness 10.4 GJB2 GJB6
28 deafness, autosomal recessive 1a 10.4 GJB2 GJB6
29 epithelial and subepithelial dystrophy 10.4 CHST6 KRT12 KRT3 TGFBI
30 congenital cytomegalovirus 10.4 GJB2 GJB6
31 hodgkin's lymphoma, nodular sclerosis 10.3 GJB2 GJB6
32 epithelial-stromal tgfbi dystrophy 10.3 CHST6 GSN KRT12 TGFBI
33 corneal ectasia 10.3 KERA VSX1
34 corneal dystrophy, gelatinous drop-like 10.3 CHST6 GSN KRT12 TGFBI
35 dfnb1 10.3 GJB2 GJB6
36 corneal dystrophy, posterior polymorphous, 2 10.3 COL8A2 SLC4A11 VSX1 ZEB1
37 auditory system disease 10.3 GJB2 GJB6 TLR9
38 vohwinkel syndrome 10.3 GJB2 GJB6
39 corneal granular dystrophy 10.3 KRT12 KRT3 TGFBI UBIAD1
40 corneal degeneration 10.2 KRT12 LCAT TGFBI VSX1
41 macular dystrophy, corneal 10.2 CHST6 KRT12 TGFBI UBIAD1
42 knuckle pads 10.2 GJB2 GJB6
43 corneal endothelial dystrophy 10.1 CHST6 COL8A2 KRT12 KRT3 SLC4A11 TGFBI
44 nervous system disease 10.1 GJB2 NGF TLR9
45 corneal dystrophy, posterior polymorphous, 3 10.1 COL8A2 SLC4A11 TGFB2 VSX1 ZEB1
46 stromal dystrophy 10.1 CHST6 KERA TGFBI UBIAD1
47 rheumatic myocarditis 10.0 GSN IL1A
48 herpes simplex 10.0
49 cataract 9.9
50 corneal dystrophy, thiel-behnke type 9.8 CHST6 COL8A2 GSN KRT12 KRT3 LCAT

Graphical network of the top 20 diseases related to Corneal Disease:



Diseases related to Corneal Disease

Symptoms & Phenotypes for Corneal Disease

UMLS symptoms related to Corneal Disease:


eye manifestations

MGI Mouse Phenotypes related to Corneal Disease:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.93 LCAT NGF SLC4A11 TGFB2 TGFBI TLR9
2 immune system MP:0005387 9.65 TGFB2 TGFBI TLR9 AGBL1 ZEB1 GJB2
3 vision/eye MP:0005391 9.4 NGF SLC4A11 TGFB2 TGFBI CHST6 VSX1

Drugs & Therapeutics for Corneal Disease

Drugs for Corneal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 485)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
2
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3 137-58-6 3676
3 Racepinephrine Approved Phase 4 329-65-7
4
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3,Phase 2 9004-61-9 53477741 24759
5
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2 104987-11-3 445643 439492
6
Ranibizumab Approved Phase 4,Phase 1 347396-82-1 459903
7
Povidone Approved Phase 4,Phase 3,Phase 2 9003-39-8
8
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
9
Loteprednol Approved Phase 4,Phase 3,Phase 2 129260-79-3, 82034-46-6 9865442 444025
10
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
11
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
12
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 299-42-3 9294
13
Latanoprost Approved, Investigational Phase 4,Phase 3 130209-82-4 5311221 5282380
14
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 90-82-4 7028
15
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 100986-85-4 149096
16
Ofloxacin Approved Phase 4,Phase 3,Phase 1,Phase 2 82419-36-1 4583
17
Bevacizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 216974-75-3
18
Glycerol Approved, Investigational Phase 4,Phase 3,Phase 2 56-81-5 753
19
Dipivefrin Approved Phase 4,Phase 3 52365-63-6 3105
20
Iodine Approved, Investigational Phase 4,Phase 3,Phase 2 7553-56-2 807
21
Povidone-iodine Approved Phase 4,Phase 3,Phase 2 25655-41-8
22
Menthol Approved Phase 4,Phase 3,Phase 2 2216-51-5 16666
23
Zinc Approved, Investigational Phase 4,Phase 2 7440-66-6 32051 23994
24
Natamycin Approved Phase 4,Phase 3,Phase 2,Phase 1 7681-93-8 5281099
25
Fluorometholone Approved, Investigational Phase 4,Phase 3,Phase 2 426-13-1 9878
26
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 564-25-0 54671203
27 Titanium dioxide Approved Phase 4 13463-67-7
28
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-28-2 5757
29
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2 57-63-6 5991
30
Moxifloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 151096-09-2, 354812-41-2 152946
31
Norgestimate Approved, Investigational Phase 4,Phase 3,Phase 2 35189-28-7 6540478
32
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
33
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
34
Azithromycin Approved Phase 4,Phase 3,Phase 2 83905-01-5 53477736 447043 55185
35
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
36
Ethanol Approved Phase 4,Phase 2 64-17-5 702
37
Difluprednate Approved Phase 4,Phase 2 23674-86-4 443936
38
Dexlansoprazole Approved, Investigational Phase 4 138530-94-6, 103577-45-3 9578005
39
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
40
Ganciclovir Approved, Investigational Phase 4,Phase 2 82410-32-0 3454
41
Isotretinoin Approved Phase 4,Phase 2 4759-48-2 5282379 5538
42
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-02-2 5743
43
Histamine Approved, Investigational Phase 4,Phase 3 51-45-6, 75614-87-8 774
44
Permethrin Approved, Investigational Phase 4 52645-53-1 40326
45
Dimenhydrinate Approved Phase 4 523-87-5 441281
46
Sorbitol Approved Phase 4 50-70-4 5780
47
Albendazole Approved, Vet_approved Phase 4 54965-21-8 2082
48
Oxymetazoline Approved, Investigational Phase 4 1491-59-4 4636
49
Phenylephrine Approved Phase 4 59-42-7 6041
50
Tropicamide Approved, Investigational Phase 4,Phase 3,Phase 1 1508-75-4 5593

Interventional clinical trials:

(show top 50) (show all 1204)

# Name Status NCT ID Phase Drugs
1 Safety and Efficacy Study of Artificial Cornea Unknown status NCT01018888 Phase 4
2 The Impact of Topical Prostaglandins on the Biomechanical Properties of the Cornea in Patients With Open Angle Glaucoma Unknown status NCT02388360 Phase 4 topical prostaglandin analogs
3 TRPV Expression in Subjects With Sensitive Skin Unknown status NCT01871883 Phase 4
4 0.3% Sodium Hyaluronate in the Treatment of Dry Eye of Diabetic Patients Unknown status NCT02595606 Phase 4 0.3% Sodium Hyaluronate
5 Evaluating Results of Neusidl Corneal Inserter in Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) Unknown status NCT01357122 Phase 4
6 Topical Tacrolimus in Vernal Keratoconjunctivitis Unknown status NCT02456025 Phase 4 Topical tacrolimus
7 Evaluation of Changes in the Parameters of Optical Coherence Tomography After Intravitreal Injection of Lucentis Unknown status NCT01669447 Phase 4
8 Oral Nutrition Impact on Tear Film Unknown status NCT01561040 Phase 4
9 Efficacy of FreshKote and Systane for the Treatment of Dry Eye and Improvement of Osmolarity Unknown status NCT01386073 Phase 4 FreshKote;Systane
10 Altaire Gel Forming Solution Versus Refresh Tears for the Treatment of Dry Eye Signs and Symptoms Unknown status NCT01382810 Phase 4 Altaire Gel forming solution;Refresh Tears
11 Comparison of Efficacy, Safety and Anti-Inflammatory Effect Between Topical 0.05%Cyclosporine A Emulsion and REFRESH® in Patients With Moderate to Severe Dry Eyes Unknown status NCT00704275 Phase 4 0.05% cyclosporin eye drop
12 Topical Cyclosporine for the Treatment of Dry Eye in Patients Infected With the Human Immunodeficiency Virus Unknown status NCT00797030 Phase 4 cyclosporine and sodium carboximethycellulose;sodium carboximethycellulose
13 A Placebo Controlled Double Masked Clinical Assessment Study of Essential Fatty Acid Supplement and Its Effect on Patients With Apparent Aqueous Deficient Dry Eye Syndrome Unknown status NCT00344721 Phase 4 Essential fatty acid supplement
14 Corneal Thickness Changes During Corneal Collagen Cross-linking With Ultraviolet-A Irradiation and Riboflavin Completed NCT01485211 Phase 4 cross-linking with hypo-osmolar riboflavin
15 Dermal Penetration of the Titanium Dioxide in Anthelios SX SPF40 Cream Completed NCT01021787 Phase 4 Titanium dioxide
16 Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty Completed NCT01853696 Phase 4 loteprednol etabonate;prednisolone acetate 1%
17 Ophthalmic Findings During 10-year Enzyme Substitution of Danish Fabry Patients. Completed NCT01997489 Phase 4 Enzyme replacement
18 Kynex Versus Refresh Plus Study in Subject With Dry Eye Completed NCT00809198 Phase 4
19 The Effects of Preservative-free Prostaglandin Eye Drops in Sign and Symptoms on the Eyes of Patients With Glaucoma Completed NCT01369771 Phase 4 Tafluprost 0.0015%
20 The Utility of in Vivo Confocal Microscopy to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With Dry Eye Disease Completed NCT02120079 Phase 4 Lotemax;Artificial Tears
21 Effect on Wound Healing of Vigamox Versus Cravit Completed NCT00840580 Phase 4 Moxifloxacin 0.5% ophthalmic solution (Vigamox);Levofloxacin 0.5% ophthalmic solution (Cravit)
22 Pain Management in Corneal Collagen Crosslinking for Keratoconus Completed NCT02867176 Phase 4 Gabapentin;Ketorolac
23 The Effect of Bevacizumab on Corneal Neovascularization Completed NCT00797303 Phase 4 Bevacizumab
24 Effect of Moisturising Creams on Skin Moisture in Atopic Dermatitis Completed NCT00846235 Phase 4
25 Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear Completed NCT01015768 Phase 4
26 Partnership for Rapid Elimination of Trachoma Completed NCT00792922 Phase 4 Azithromycin;Azithromycin
27 Role of Sub-Conjunctival Bevacizumab in Post Pterygium Excision Management Completed NCT01736449 Phase 4 Bevacizumab
28 Effects of Contact Lens Care Regimens on the Corneal Epithelium Completed NCT00349882 Phase 4 Marketed multipurpose disinfection regimen
29 Comparison of Two Multi-Purpose Solution and Lens Material Combinations on Corneal Barrier Function Completed NCT00560898 Phase 4 ProClear Lens Material soaked in ReNu Multiplus Multipurpose Solution;Acuvue Advance Lens Material soaked in ReNu Multiplus Multipurpose Solution;Acuvue Advance Lens Material soaked in Optifree RepleniSH Multipurpose Solution;ProClear Lens Material soaked in Optifree RepleniSH Multipurpose Solution
30 Anterior Stromal Changes After PRK by Using Intraoperative Mitomicin C Completed NCT00599950 Phase 4 Mitomycin C and Photorefractive keratectomy (PRK)
31 Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia Completed NCT00347776 Phase 4 azithromycin;topical tetracycline
32 Comparison of Toric IOL Implantation and Opposite Clear Corneal Incision During Cataract Surgery to Correct Corneal Astigmatism Completed NCT01763151 Phase 4
33 2-Site Safety Study of Besivance Versus Vigamox Prophylactically in Routine Cataract Surgery Completed NCT01455233 Phase 4 besivance;vigamox
34 Mechanical vs. Alcohol Separation of the Corneal Epithelium During Surface Ablation Refractive Procedures Completed NCT00366808 Phase 4
35 Dropless™ vs. Less Drops™ Pharmaceutical Regimens After Cataract Surgery Completed NCT02819908 Phase 4 Imprimis Dropless;Imprimis Less Drops
36 Comparison of Functional Vision Provided by AMO Tecnis Z9000 and Alcon SA60AT Acrysof Completed NCT00459303 Phase 4
37 Soothe Versus Refresh Completed NCT00284999 Phase 4 Soothe;Refresh Tears
38 Comparison of Ex-PRESSTM Mini Glaucoma Shunt to Trabeculectomy in Subjects With Open Angle Glaucoma Completed NCT00444080 Phase 4
39 Povidone-iodine Antisepsis for Strabismus Surgery Completed NCT00461656 Phase 4 Preoperative conjunctival irrigation with 5% or 1.25% PI
40 Corneal Endothelial Changes Associated With Phacoemulsification in Diabetes Mellitus Type II Completed NCT01078103 Phase 4
41 Effect of CACICOL20 on Corneal Epithelial Healing After Cross-linking in Patients With Keratoconus Completed NCT02119039 Phase 4
42 Comparison of DisCoVisc and Hydroxypropylmethylcellulose 2% Completed NCT01387620 Phase 4 Hyaluronic Acid and hydroxypropylmethylcellulose
43 Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision Lenses Completed NCT01268306 Phase 4
44 Intrastromal Corneal Ring Segment Implantation in 219 Keratoconic Eyes at Different Stages Completed NCT01261013 Phase 4
45 Comparison Of Trabeculectomy Versus The Ex-PRESS Miniature Glaucoma Device In The Same Patient: A Prospective Randomized Study Completed NCT00698438 Phase 4
46 Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface Completed NCT01250925 Phase 4 ReNu MultiPlus® MultiPurpose Solution;OPTI-FREE® RepleniSH®;Clear Care®
47 The Effects of BAK on the Blood Aqueous Barrier of Pseudophakic Patients Completed NCT01280110 Phase 4 Hydroxypropylmethylcellulose;Carboxymethylcellulose
48 Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery. Completed NCT01244334 Phase 4 Difluprednate ophthalmic emulsion 0.05%;Prednisolone acetate 1%
49 Relationship Between Central Corneal Thickness and Intraocular Pressure Measures Instruments. Completed NCT00347191 Phase 4
50 Safety and Efficacy of Lansoprazole in Patients With Reflux Disease Completed NCT01135368 Phase 4 Lansoprazole

Search NIH Clinical Center for Corneal Disease

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: corneal diseases

Genetic Tests for Corneal Disease

Anatomical Context for Corneal Disease

MalaCards organs/tissues related to Corneal Disease:

38
Eye, Endothelial, Skin, Testes, Thyroid, Bone, Colon

Publications for Corneal Disease

Articles related to Corneal Disease:

(show top 50) (show all 165)
# Title Authors Year
1
Mitochondrial dysfunction and oxidative stress in corneal disease. ( 28549842 )
2017
2
Umbilical cord stem cells in the treatment of corneal disease. ( 28232219 )
2017
3
State of the Art and Beyond: Anterior Segment Diagnostics Genetic Diagnostics in Corneal Disease. ( 28590278 )
2017
4
Population-based assessment of vision-related quality of life in corneal disease: results from the CORE study. ( 26917676 )
2016
5
Keratoconus; a True Corneal Disease. ( 27195077 )
2016
6
Long-Term Results of the Boston Keratoprosthesis for Unilateral Corneal Disease. ( 26114818 )
2015
7
Evaluation of a low-cost design keratoprosthesis in end-stage corneal disease: a preliminary study. ( 26271267 )
2015
8
Reinhard T, Larkin F (eds), Corneal Disease 2013, ISBN: 978-3-642-28746-6, Springer. ( 26371062 )
2015
9
Prior Corneal Scarification and Injection of Immune Serum are Not Required Before Ocular HSV-1 Infection for UV-B-Induced Virus Reactivation and Recurrent Herpetic Corneal Disease in Latently Infected Mice. ( 26398722 )
2015
10
Comparing biometry in normal eyes of children with unilateral cataract/corneal disease to age-matched controls. ( 27363955 )
2015
11
Partial lamellar keratoplasty for peripheral corneal disease using a graft from the glycerin-preserved corneoscleral rim. ( 24796771 )
2014
12
Telemedicine for corneal disease in rural Nepal. ( 24906650 )
2014
13
Equine deep stromal abscesses (51 cases - 2004-2009) - Part 1: the clinical aspects with attention to the duration of the corneal disease, treatment history, clinical appearance, and microbiology results. ( 24131726 )
2013
14
Novel therapeutic approaches for corneal disease. ( 23725602 )
2013
15
Cataract surgery in patients with corneal disease. ( 23197265 )
2013
16
Metaherpetic corneal disease in a dog associated with partial limbal stem cell deficiency and neurotrophic keratitis. ( 22958361 )
2013
17
A retrospective survey of the ocular histopathology of the pinniped eye with emphasis on corneal disease. ( 22812701 )
2013
18
Keratocyte progenitor cell transplantation: A novel therapeutic strategy for corneal disease. ( 23200457 )
2013
19
Transmembrane water-flux through SLC4A11: a route defective in genetic corneal diseases. ( 23813972 )
2013
20
Mosaic Chromosome 18q Partial Deletion Syndrome with Bilateral Full-thickness Corneal Disease: Surgical Intervention and Histopathology. ( 24024746 )
2013
21
Nerve growth factor therapy for corneal disease. ( 22543481 )
2012
22
Pilot Study for OCT Guided Design and Fit of a Prosthetic Device for Treatment of Corneal Disease. ( 23316338 )
2012
23
Corneal disease in China. ( 22858025 )
2012
24
Correlation of clinical and pathologic diagnoses of corneal disease in penetrating keratoplasties in Vancouver: a 10-year review. ( 22333843 )
2012
25
Suppression of transcription factor early growth response 1 reduces herpes simplex virus 1-induced corneal disease in mice. ( 22647700 )
2012
26
Using soybean trypsin inhibitor as an external loading control for Western blot analysis of tear proteins: application to corneal disease. ( 22498032 )
2012
27
Treatment of corneal disease with traditional Tibetan medicine: a report of four cases. ( 21505551 )
2011
28
B7 costimulation molecules encoded by replication-defective, vhs-deficient HSV-1 improve vaccine-induced protection against corneal disease. ( 21826207 )
2011
29
Penetrating keratoplasty for unilateral corneal disease: outcomes from a tertiary care hospital in Australia. ( 19927002 )
2010
30
Dystrophia Helsinglandica--corneal morphology, topography and sensitivity in a hereditary corneal disease with recurrent erosive episodes. ( 20597871 )
2010
31
Intracorneal ring segments in ectatic corneal disease - a review. ( 20398105 )
2010
32
Histopathology and treatment of corneal disease in keratitis, ichthyosis, and deafness (KID) syndrome. ( 19590522 )
2010
33
Age-related T-cell cytokine profile parallels corneal disease severity in Sjogren's syndrome-like keratoconjunctivitis sicca in CD25KO mice. ( 20007286 )
2010
34
Parachlamydia acanthamoebae in domestic cats with and without corneal disease. ( 20618801 )
2010
35
Pattern of bilateral blinding corneal disease in patients waiting for keratoplasty in a tertiary eye care centre in northern India. ( 20118783 )
2010
36
Collagen cross-linking: a new treatment paradigm in corneal disease - a review. ( 20398104 )
2010
37
[Research and development for treating devastating corneal diseases]. ( 20387535 )
2010
38
Pellucid marginal corneal disease in a case of atopic keratoconjunctivitis. ( 20482394 )
2010
39
Managing corneal disease: focus on suppurative keratitis. ( 20212926 )
2009
40
A new corneal disease with recurrent erosive episodes and autosomal-dominant inheritance. ( 18778339 )
2008
41
Disruption of CFTR-dependent lipid rafts reduces bacterial levels and corneal disease in a murine model of Pseudomonas aeruginosa keratitis. ( 18326723 )
2008
42
Apolipoprotein E alleles can contribute to the pathogenesis of numerous clinical conditions including HSV-1 corneal disease. ( 17007837 )
2007
43
Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity. ( 17905228 )
2007
44
Interleukin-10 (IL-10) ameliorates corneal disease in a mouse model of recurrent herpetic keratitis. ( 15652291 )
2005
45
Genetics of corneal disease for the ocular surface clinician. ( 17131020 )
2005
46
Feline corneal disease. ( 15948422 )
2005
47
Inherited corneal disease: the evolving molecular, genetic and imaging revolution. ( 15932539 )
2005
48
Clinical experience with butyl-2-cyanoacrylate adhesive in the management of canine and feline corneal disease. ( 15310291 )
2004
49
Two patients with severe corneal disease in KID syndrome. ( 14700667 )
2004
50
Distribution of TFF peptides in corneal disease and pterygium. ( 15177877 )
2004

Variations for Corneal Disease

Expression for Corneal Disease

Search GEO for disease gene expression data for Corneal Disease.

Pathways for Corneal Disease

Pathways related to Corneal Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.92 IL1A ZEB1

GO Terms for Corneal Disease

Cellular components related to Corneal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proteinaceous extracellular matrix GO:0005578 9.46 COL8A2 KERA TGFBI TLR9
2 extracellular region GO:0005576 9.28 COL8A2 GSN IL1A KERA LCAT NGF
3 connexin complex GO:0005922 8.96 GJB2 GJB6

Biological processes related to Corneal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 visual perception GO:0007601 9.26 KERA KRT12 TGFBI VSX1
2 inner ear development GO:0048839 8.8 GJB2 GJB6 TGFB2

Molecular functions related to Corneal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 8.62 IL1A TLR9

Sources for Corneal Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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