MCID: CRN025
MIFTS: 41

Corneal Dystrophy

Categories: Genetic diseases, Eye diseases

Aliases & Classifications for Corneal Dystrophy

MalaCards integrated aliases for Corneal Dystrophy:

Name: Corneal Dystrophy 12 24 29 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2566
ICD10 33 H18.5 H18.50
ICD9CM 35 371.5 371.50
MeSH 42 D003317

Summaries for Corneal Dystrophy

MalaCards based summary : Corneal Dystrophy is related to corneal dystrophy, avellino type and corneal dystrophy, reis-bucklers type. An important gene associated with Corneal Dystrophy is ZEB1 (Zinc Finger E-Box Binding Homeobox 1). The drugs Loteprednol and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include endothelial, eye and testes, and related phenotype is vision/eye.

Wikipedia : 72 Corneal dystrophy is a group of rare hereditary disorders characterised by bilateral abnormal deposition... more...

Related Diseases for Corneal Dystrophy

Diseases related to Corneal Dystrophy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 124)
id Related Disease Score Top Affiliating Genes
1 corneal dystrophy, avellino type 34.5 TACSTD2 TGFBI
2 corneal dystrophy, reis-bucklers type 34.4 GSN TGFBI
3 corneal dystrophy, fuchs endothelial, 4 34.1 COL8A2 SLC4A11 TGFBI
4 corneal dystrophy, lattice type iiia 34.0 CHST6 TGFBI
5 corneal dystrophy, posterior polymorphous 2 33.9 COL8A2 SLC4A11 VSX1 ZEB1
6 corneal dystrophy, gelatinous drop-like 33.9 CHST6 GSN KRT12 TACSTD2 TGFBI
7 corneal dystrophy, fuchs endothelial, 6 33.5 COL8A2 OVOL2 SLC4A11 VSX1 ZEB1
8 corneal dystrophy, epithelial basement membrane 33.0 CHST6 COL8A2 GSN KRT12 KRT3 SLC4A11
9 epithelial basement membrane dystrophy 32.5 CHST6 GSN KRT12 TACSTD2 TGFBI
10 macular corneal dystrophy 12.6
11 meesmann corneal dystrophy 12.5
12 corneal dystrophy, thiel-behnke type 12.4
13 corneal dystrophy, posterior polymorphous, 1 12.4
14 corneal dystrophy, lattice type i 12.4
15 corneal dystrophy, congenital stromal 12.4
16 corneal dystrophy, groenouw type i 12.3
17 corneal dystrophy, schnyder type 12.3
18 lattice corneal dystrophy 12.3
19 corneal dystrophy, fuchs endothelial, 3 12.2
20 fuchs' endothelial dystrophy 12.2
21 corneal dystrophy, posterior polymorphous, 3 12.2
22 lattice corneal dystrophy type ii 12.2
23 corneal dystrophy, fuchs endothelial, 1 12.1
24 corneal dystrophy, fuchs endothelial, 8 12.1
25 spinocerebellar degeneration and corneal dystrophy 12.1
26 corneal dystrophy, fuchs endothelial, 5 12.1
27 corneal dystrophy, fuchs endothelial, 2 12.1
28 corneal dystrophy, lisch epithelial 12.1
29 corneal dystrophy, endothelial, x-linked 12.1
30 corneal dystrophy, subepithelial mucinous 12.0
31 corneal dystrophy, posterior amorphous 12.0
32 spinocerebellar degeneration with macular corneal dystrophy, congenital cataracts, and myopia 12.0
33 pre-descemet corneal dystrophy 12.0
34 corneal fleck dystrophy 11.9
35 grayson-wilbrandt corneal dystrophy 11.9
36 honey-droplet corneal dystrophy 11.9
37 corneal endothelial dystrophy and perceptive deafness 11.8
38 corneal dystrophy, fuchs endothelial, 7 11.8
39 corneal dystrophy ichthyosis microcephaly mental retardation 11.8
40 corneal dystrophy pigmentary anomaly malabsorption 11.8
41 corneal granular dystrophy 11.7
42 corneal endothelial dystrophy, autosomal recessive 11.7
43 corneodermatoosseous syndrome 11.6
44 corneal endothelial dystrophy type 2 11.5
45 bietti crystalline corneoretinal dystrophy 11.5
46 rutherfurd syndrome 11.5
47 amyloidosis, finnish type 11.4
48 mousa al din al nassar syndrome 11.4
49 central cloudy dystrophy of francois 11.1
50 epithelial recurrent erosion dystrophy 11.1

Graphical network of the top 20 diseases related to Corneal Dystrophy:



Diseases related to Corneal Dystrophy

Symptoms & Phenotypes for Corneal Dystrophy

MGI Mouse Phenotypes related to Corneal Dystrophy:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 vision/eye MP:0005391 9.44 COL8A2 CYP4V2 DCN KRT12 MBNL1 OVOL2

Drugs & Therapeutics for Corneal Dystrophy

Drugs for Corneal Dystrophy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 53)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Loteprednol Approved Phase 4 82034-46-6, 129260-79-3 444025 9865442
2
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 4,Phase 2 50-24-8 5755
4 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1,Phase 2
5 Anti-Allergic Agents Phase 4,Phase 2
6 Antiemetics Phase 4,Phase 2
7 Anti-Inflammatory Agents Phase 4,Phase 2
8 Antineoplastic Agents, Hormonal Phase 4,Phase 2
9 Autonomic Agents Phase 4,Phase 1,Phase 2
10 Gastrointestinal Agents Phase 4,Phase 2
11 glucocorticoids Phase 4,Phase 2
12 Hormone Antagonists Phase 4,Phase 2
13 Hormones Phase 4,Phase 2
14 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2
15 Methylprednisolone acetate Phase 4,Phase 2
16 Methylprednisolone Hemisuccinate Phase 4,Phase 2
17 Neuroprotective Agents Phase 4,Phase 2
18 Ophthalmic Solutions Phase 4,Phase 3,Phase 1,Phase 2
19 Peripheral Nervous System Agents Phase 4,Phase 1,Phase 2
20 Prednisolone acetate Phase 4,Phase 2
21 Prednisolone hemisuccinate Phase 4,Phase 2
22 Prednisolone phosphate Phase 4,Phase 2
23 Protective Agents Phase 4,Phase 2,Phase 1
24 Tetrahydrozoline Phase 4,Phase 3,Phase 1,Phase 2
25
Riboflavin Approved, Nutraceutical, Vet_approved Phase 3 83-88-5 493570
26 Vitamin B2 Nutraceutical Phase 3
27
Ephedrine Approved Phase 1, Phase 2 299-42-3 9294
28
Pseudoephedrine Approved Phase 1, Phase 2 90-82-4 7028
29
Fluorometholone Approved Phase 2 426-13-1 9878
30
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
31 Nasal Decongestants Phase 1, Phase 2
32 Respiratory System Agents Phase 1, Phase 2
33 Vasoconstrictor Agents Phase 1, Phase 2
34 HIV Protease Inhibitors Phase 2
35
protease inhibitors Phase 2
36 BB 1101 Phase 2
37 Dexamethasone acetate Phase 2 1177-87-3
38
Fomepizole Approved, Vet_approved Phase 1 7554-65-6 3406
39 Antidotes Phase 1
40
Hyaluronic acid Approved, Vet_approved 9004-61-9 53477741 24759
41 Matrix Metalloproteinase Inhibitors
42 Superoxide Dismutase
43 TIMP1 protein, human
44 TIMP3 protein, human
45 Tissue Inhibitor of Metalloproteinase-1
46 Tissue Inhibitor of Metalloproteinase-3
47 Tissue Inhibitor of Metalloproteinases
48 Adjuvants, Immunologic
49 Viscosupplements
50 Anti-Bacterial Agents

Interventional clinical trials:

(show top 50) (show all 61)

id Name Status NCT ID Phase Drugs
1 Evaluating Results of Neusidl Corneal Inserter in Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) Unknown status NCT01357122 Phase 4
2 Fuchs' Torsional Phaco Study Completed NCT00781027 Phase 4
3 Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty Completed NCT01853696 Phase 4 loteprednol etabonate;prednisolone acetate 1%
4 Intrastromal Corneal Ring for High Astigmatism on Postkeratoplasty Completed NCT01018797 Phase 4
5 Glanatec(R) for Descemet Stripping in Fuch's Endothelial Dystrophy Not yet recruiting NCT03249337 Phase 4 Ripasudil hydrochloride hydrate 0.4% ophthalmic solution
6 Cacicol20® in Corneal Wound Healing and Nerve Regeneration After Phototherapeutic Keratectomy Terminated NCT02373397 Phase 4
7 The Effects of Corneal Collagen Cross-linking Recruiting NCT01708538 Phase 3 CXL
8 Trial of Netarsudil for Prevention of Corticosteroid-induced Intraocular Pressure Elevation Not yet recruiting NCT03248037 Phase 3 Netarsudil;Placebo
9 Utilization of Amniotic Membrane Extract Eye Drop (AMEED) on Human Corneal Healing Completed NCT02746848 Phase 1, Phase 2
10 Comparison of Two Steroid Regimens to Prevent Transplant Rejection After Corneal Transplant (DMEK) Completed NCT01448213 Phase 2 Prednisolone acetate;Fluorometholone
11 A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial Dystrophy (FCED) Recruiting NCT02653391 Phase 1, Phase 2 Elamipretide 1.0% Ophthalmic Solution;Elamipretide 3.0% Ophthalmic Solution
12 Immunosuppression During Penetrating Keratoplasty, Using a Subconjunctival Implant Releasing Dexamethasone : Tolerance and Safety Pilot Study Recruiting NCT02834260 Phase 2 Dexamethasone implant OZURDEX
13 Phase 1 Pilot Study of 4-MP to Treat Stargardt Macular Dystrophy Completed NCT00346853 Phase 1 4-Methylpyrazole
14 Corneal Endothelium Morphology and Central Thickness in Type II Diabetes Mellitus and Normal Subjects Unknown status NCT01084850
15 Early Experience With Descemet's Stripping Automated Endothelial Keratoplasty Unknown status NCT00744796
16 Comparison of Corneal Grafts Cultured in Serum-free Versus Corneal Grafts Cultured in Serum Supplemented Culture Media Unknown status NCT00623584
17 Hyper-CL™ Lens (Hyper Osmotic Contact Lens) In Subjects Suffering From Corneal Edema Unknown status NCT01890252 saline solution
18 Outcome After Descemet Membrane Endothelial Keratoplasty (DMEK) and Ultra-thin Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) Unknown status NCT02020044
19 Cornea Donor Study Unknown status NCT00006411
20 Comparing Endoglide to Endoserter for DSAEK Graft Insertion Unknown status NCT01791075
21 Observational Study of Corneal Opacities in Adults Unknown status NCT02109471
22 Transplantation of Tissue Cultured Human Amniotic Epithelial Cells Onto Damaged Ocular Surfaces Unknown status NCT00344708
23 Studies in Families With Corneal Dystrophy or Other Inherited Corneal Diseases Completed NCT00357435
24 Combined Cataract Surgery and Planned Descemetorhexis Completed NCT02206594
25 Fuchs' Endothelial Dystrophy: Clinical Characteristics, Treatment Outcome, and Pathology Completed NCT01979250
26 Optimizing the Ocular Surface Prior to Cataract Surgery Completed NCT02766907
27 Evaluation of Tomographic and Genetic Aspects of Keratoconus Patients Compared to Sounds Corneas Completed NCT03071302
28 Laser Assisted Procedures in Penetrating Keratoplasty Completed NCT02173847
29 ODM 5 in the Treatment of Corneal Edematous Fuchs' Endothelial Dystrophy Completed NCT02332109
30 Comparison of Two Techniques in Achieving Corneal Graft Completed NCT01610973
31 Study of Eye Bank Pre-cut Donor Grafts for Endothelial Keratoplasty Completed NCT00624221
32 A Comparison Between Full Thickness and Partial Thickness Corneal Transplantation for Corneal Edema Completed NCT00346138
33 Impact of Cataract Surgery on Keratoplasty Graft Survival Completed NCT02875145
34 Influence of Cosmetic Color Tinted Contact Lenses on the Ocular Surface Completed NCT01441648
35 The Molecular Pathogenesis of Late-onset Fuchs' Endothelial Corneal Dystrophy Recruiting NCT01795001
36 Descemet Membrane Endothelial Keratoplasty (DMEK) Recruiting NCT00521898
37 Descemet Stripping (Automated) Endothelial Keratoplasty (DSEK or DSAEK) Recruiting NCT00543660
38 Autologous Adipose-Derived Adult Stem Cell Transplantation for Corneal Diseases Recruiting NCT02932852 Early Phase 1
39 DMEK Versus DSAEK Study Recruiting NCT02793310
40 DSAEK- Postoperative Positioning and Transplant Dislocation Recruiting NCT01206127
41 Study of Using the Hyper-CL™ Lens (Hyper Osmotic Contact Lens) in Subjects Suffering From Corneal Edema Recruiting NCT02660151 Salt solution
42 Clinical Efficacy of the Pinhole Soft Contact Lenses for Correcting Presbyopia Recruiting NCT02612584
43 Topical Anesthesia for Closed PKP vs Retrobulbar Anesthesia for Open-sky PKP Recruiting NCT02826174 Anti-Rejection Agents;Anti-Inflammatory Agents
44 Study of Endothelial Keratoplasty Outcomes Recruiting NCT00800111
45 Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford Recruiting NCT01793168
46 Spectral-domain Optical Coherence Tomography of the Eye Recruiting NCT02614625
47 Evaluation of the Efficacy of Descemet Membrane Transplantation for the Treatment of Fuchs' Endothelial Dystrophy Recruiting NCT03275896 Early Phase 1
48 Long Term Cornea Graft Survival Study Recruiting NCT02849808
49 Technique And Results In Endothelial Keratoplasty Recruiting NCT02470793
50 DISCOVER Study: Microscope-integrated Intraoperative OCT Study Recruiting NCT02423213

Search NIH Clinical Center for Corneal Dystrophy

Genetic Tests for Corneal Dystrophy

Genetic tests related to Corneal Dystrophy:

id Genetic test Affiliating Genes
1 Corneal Dystrophy 29 24 CYP4V2

Anatomical Context for Corneal Dystrophy

MalaCards organs/tissues related to Corneal Dystrophy:

39
Endothelial, Eye, Testes, Kidney, Cerebellum, Skin

Publications for Corneal Dystrophy

Articles related to Corneal Dystrophy:

(show top 50) (show all 839)
id Title Authors Year
1
Posterior Amorphous Corneal Dystrophy Associated With Keratoglobus: A Case Report. ( 28902010 )
2017
2
Trinucleotide Repeat Expansion in the Transcription Factor 4 (TCF4) Gene Leads to Widespread mRNA Splicing Changes in Fuchs' Endothelial Corneal Dystrophy. ( 28118661 )
2017
3
Ex vivo 3D human corneal stroma model for Schnyder corneal dystrophy - role of autophagy in its pathogenesis and resolution. ( 28872183 )
2017
4
Fuchs' Endothelial Corneal Dystrophy and RNA Foci in Patients With Myotonic Dystrophy. ( 28886202 )
2017
5
Activation of mitophagy leads to decline in Mfn2 and loss of mitochondrial mass in Fuchs endothelial corneal dystrophy. ( 28751712 )
2017
6
Recurrence of Granular Corneal Dystrophy Type 1 After Phototherapeutic Keratectomy, Lamellar Keratoplasty, and Penetrating Keratoplasty in a Single Population. ( 28749898 )
2017
7
Extracellular Matrix and Integrin Expression Profiles in Fuchs Endothelial Corneal Dystrophy Cells and Tissue Model. ( 28726551 )
2017
8
Activation of TGF-I^ signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy. ( 28754918 )
2017
9
Thick keratoconic cornea associated with posterior polymorphous corneal dystrophy. ( 28089285 )
2017
10
Meretoja's Syndrome: Lattice Corneal Dystrophy, Gelsolin Type. ( 28250773 )
2017
11
Proteomic Analysis of Amyloid Corneal Aggregates from TGFBI-H626R Lattice Corneal Dystrophy Patient Implicates Serine-Protease HTRA1 in Mutation-Specific Pathogenesis of TGFBIp. ( 28689406 )
2017
12
Melatonin reduces endoplasmic reticulum stress and corneal dystrophy-associated TGFBIp through activation of endoplasmic reticulum-associated protein degradation. ( 28580641 )
2017
13
Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy. ( 28654985 )
2017
14
Corneal Backscatters as an Objective Index for Assessing Fuchs' Endothelial Corneal Dystrophy: A Pilot Study. ( 28751984 )
2017
15
Effect of position-specific single-point mutations and biophysical characterization of amyloidogenic peptide fragments identified from lattice corneal dystrophy patients. ( 28381645 )
2017
16
Vortex Pattern of Corneal Deposits in Granular Corneal Dystrophy Associated With the p.(Arg555Trp) Mutation in TGFBI. ( 28060069 )
2017
17
Automated Retroillumination Photography Analysis for Objective Assessment of Fuchs Corneal Dystrophy. ( 27811565 )
2017
18
CTG18.1 Expansion in TCF4 Increases Likelihood of Transplantation in Fuchs Corneal Dystrophy. ( 27755191 )
2017
19
Gelatinous drop-like corneal dystrophy: a review. ( 27913443 )
2017
20
Agenesis of the corpus callosum, developmental delay, autism spectrum disorder, facial dysmorphism, and posterior polymorphous corneal dystrophy associated with ZEB1 gene deletion. ( 28742278 )
2017
21
Posterior Polymorphous Corneal Dystrophy ( 28613630 )
2017
22
Vps35-deficiency impairs SLC4A11 trafficking and promotes corneal dystrophy. ( 28934248 )
2017
23
Confirmation of the OVOL2 Promoter Mutation c.-307T>C in Posterior Polymorphous Corneal Dystrophy 1. ( 28046031 )
2017
24
TGC repeat expansion in the TCF4 gene increases the risk of Fuchs' endothelial corneal dystrophy in Australian cases. ( 28832669 )
2017
25
The Changing Face of Aging: Highly Sulfated Glycosaminoglycans Induce Amyloid Formation in a Lattice Corneal Dystrophy Model Protein. ( 28739480 )
2017
26
Mutation analysis of TGFBI and KRT12 in a case of concomitant keratoconus and granular corneal dystrophy. ( 28567551 )
2017
27
Photorefractive Keratectomy With Mitomycin C in Meesmann's Epithelial Corneal Dystrophy. ( 28068448 )
2017
28
Two mutations in the transforming growth factor beta-induced gene associated with familial Lattice corneal dystrophy. ( 28393022 )
2017
29
Peripheral Endothelial Cell Count Is a Predictor of Disease Severity in Advanced Fuchs Endothelial Corneal Dystrophy. ( 28731879 )
2017
30
Intracorneal melatonin delivery using 2-hydroxypropyl-I^-cyclodextrin ophthalmic solution for granular corneal dystrophy type 2. ( 28694094 )
2017
31
In vivo confocal microscopy of pre-Descemet corneal dystrophy associated with X-linked ichthyosis: a case report. ( 28302098 )
2017
32
Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy. ( 28727885 )
2017
33
TGFBI Gene Mutation Analysis in Chinese Families with Corneal Dystrophies. ( 27348782 )
2016
34
SLC4A11 Three-Dimensional Homology Model Rationalizes Corneal Dystrophy-Causing Mutations. ( 27925686 )
2016
35
Posterior amorphous corneal dystrophy caused by a de novo deletion. ( 27096414 )
2016
36
Variant lattice corneal dystrophy associated with compound heterozygous mutations in the TGFBI gene. ( 27402970 )
2016
37
In Vivo Imaging of Corneal Endothelial Dystrophy in Boston Terriers: A Spontaneous, Canine Model for Fuchs' Endothelial Corneal Dystrophy. ( 27454658 )
2016
38
Racial/Ethnic Differences in Rates of Penetrating or Endothelial Keratoplasty for Fuchs Endothelial Corneal Dystrophy Among US Medicare Beneficiaries. ( 27533017 )
2016
39
Familial Gelatinous Drop-Like Corneal Dystrophy Caused by a Novel Nonsense TACSTD2 Mutation. ( 27149532 )
2016
40
Fuchs' endothelial corneal dystrophy: a controlled prospective study on visual recovery after endothelial keratoplasty. ( 27273977 )
2016
41
Clinical characterization of posterior polymorphous corneal dystrophy in patients of Indian ethnicity. ( 27658681 )
2016
42
Microcephaly, dysmorphic features, corneal dystrophy, hairy nipples, underdeveloped labioscrotal folds, and small cerebellum in four patients. ( 27075597 )
2016
43
Corneal Astigmatism Stability in Descemet Membrane Endothelial Keratoplasty for Fuchs Corneal Dystrophy. ( 27191667 )
2016
44
[TGC Repeats in Intron 2 of the TCF4 Gene have a Good Predictive Power Regarding to Fuchs Endothelial Corneal Dystrophy]. ( 26280645 )
2016
45
Sensitive Surface Enhanced Raman Scattering-Based Detection of a BIGH3 Point Mutation Associated with Avellino Corneal Dystrophy. ( 27934116 )
2016
46
Contact lens fitting in a patient with Alport syndrome and posterior polymorphous corneal dystrophy: a case report. ( 26840166 )
2016
47
4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2. ( 27373828 )
2016
48
Small-incision lenticule extraction in posterior polymorphic corneal dystrophy. ( 27255258 )
2016
49
Delayed Onset of Lattice Corneal Dystrophy Type IIIA Due to a Novel T621P Mutation in TGFBI. ( 27163623 )
2016
50
A Case of Transforming Growth Factor-I^-Induced Gene-Related Oculorenal Syndrome: Granular Corneal Dystrophy Type II with a Unique Nephropathy. ( 27781206 )
2016

Variations for Corneal Dystrophy

ClinVar genetic disease variations for Corneal Dystrophy:

6
id Gene Variation Type Significance SNP ID Assembly Location
1 ZEB1 NM_030751.5(ZEB1): c.1576dup (p.Val526Glyfs) duplication Pathogenic GRCh37 Chromosome 10, 31809839: 31809839

Expression for Corneal Dystrophy

Search GEO for disease gene expression data for Corneal Dystrophy.

Pathways for Corneal Dystrophy

GO Terms for Corneal Dystrophy

Cellular components related to Corneal Dystrophy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 proteinaceous extracellular matrix GO:0005578 9.46 COL8A1 COL8A2 DCN TGFBI
2 extracellular matrix GO:0031012 9.26 COL8A1 COL8A2 DCN TGFBI
3 basement membrane GO:0005604 8.8 COL8A1 COL8A2 TGFBI

Biological processes related to Corneal Dystrophy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 angiogenesis GO:0001525 9.46 COL8A1 COL8A2 OVOL2 TGFBI
2 camera-type eye morphogenesis GO:0048593 9.32 COL8A1 COL8A2
3 epithelial cell proliferation GO:0050673 9.26 COL8A1 COL8A2
4 extracellular matrix organization GO:0030198 9.26 COL8A1 COL8A2 DCN TGFBI
5 visual perception GO:0007601 9.02 CYP4V2 KRT12 TACSTD2 TGFBI VSX1

Molecular functions related to Corneal Dystrophy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular matrix binding GO:0050840 8.62 DCN TGFBI

Sources for Corneal Dystrophy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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