Aliases & Classifications for Corneal Edema

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Corneal Edema, Aliases & Descriptions:

Name: Corneal Edema 9 11 60
Corneal Edema, Unspecified 9
Unspecified Corneal Edema 9
 
Corneal Edema Nos 9
Corneal Oedema 9
Cornea Edema 9


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Disease Ontology9 DOID:11030
MeSH33 D015715
ICD9CM27 371.2, 371.20
NCIt38 C50508

Summaries for Corneal Edema

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MalaCards based summary: Corneal Edema, also known as corneal edema, unspecified, is related to corneal dystrophy, posterior polymorphous, 1 and corneal dystrophy. An important gene associated with Corneal Edema is KRT8 (keratin 8), and among its related pathways are Matrix Metalloproteinases and Cell adhesion Cell matrix glycoconjugates. The drugs sodium chloride and sodium chloride granules and the compounds uva 1 and ilomastat have been mentioned in the context of this disorder. Affiliated tissues include eye and endothelial, and related mouse phenotypes are vision/eye and immune system.

Related Diseases for Corneal Edema

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Diseases in the Corneal Edema family:

Secondary Corneal Edema

Diseases related to Corneal Edema via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 62)
idRelated DiseaseScoreTop Affiliating Genes
1corneal dystrophy, posterior polymorphous, 130.7VSX1
2corneal dystrophy30.2SLC4A11, VSX1, FBXO7
3keratopathy30.2FBXO7, PBK
4keratoconus30.2FBXO7, MMP3, MMP1, VSX1
5cataract10.7
6endotheliitis10.6
7idiopathic corneal edema10.5
8contact lens corneal edema10.4
9secondary corneal edema10.4
10uveitis10.3
11intervertebral disc disease10.3IL1B
12periodontitis10.3IL1B
13keratitis10.3
14hypoxia10.3
15irregular astigmatism10.3VSX1, FBXO7
16fuchs' endothelial dystrophy10.2
17retinitis10.2
18anterior uveitis10.2
19interstitial keratitis10.1
20tularemia10.1
21corneal dystrophy, fuchs endothelial, 510.0
22corneal dystrophy, fuchs endothelial, 610.0
23corneal dystrophy, fuchs endothelial, 810.0
24corneal dystrophy, fuchs endothelial, 410.0
25glaucoma 3a, primary open angle, congenital, juvenile, or adult onset10.0
26pearson syndrome10.0
27rubella10.0
28exophthalmos10.0
29recurrent corneal erosion10.0
30coloboma10.0
31bullous keratopathy10.0
32allergic conjunctivitis10.0
33conjunctivitis10.0
34herpes simplex10.0
35keratoconjunctivitis10.0
36melanoma10.0
37neuropathy10.0
38retinal detachment10.0
39congenital rubella10.0
40pellucid marginal degeneration10.0
41stromal keratitis10.0
42essential iris atrophy10.0
43epidermolysis bullosa dystrophica10.0MMP1, MMP3
44conjunctivochalasis10.0MMP1, MMP3
45gingivitis9.9MMP1, IL1B
46abdominal aortic aneurysm9.9MMP1, MMP3
47basal cell carcinoma9.9KRT8, MMP1, MMP3
48pulmonary fibrosis9.9MMP1, IL1B, KRT8
49pulmonary fibrosis, idiopathic9.9MMP1, IL1B
50fibrosarcoma9.8KRT8, MMP1, MMP3

Graphical network of the top 20 diseases related to Corneal Edema:



Diseases related to corneal edema

Symptoms for Corneal Edema

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Drugs & Therapeutics for Corneal Edema

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Drug clinical trials:

Search ClinicalTrials for Corneal Edema

Search NIH Clinical Center for Corneal Edema

Inferred drug relations via UMLS60/NDF-RT39:

Genetic Tests for Corneal Edema

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Anatomical Context for Corneal Edema

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MalaCards organs/tissues related to Corneal Edema:

31
Eye, Endothelial

Animal Models for Corneal Edema or affiliated genes

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MGI Mouse Phenotypes related to Corneal Edema:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.6SLC4A11, VSX1, OVOL2, FBXO7
2MP:00053877.6KRT8, FBXO7, MMP3, MMP1, PBK, IL1B

Publications for Corneal Edema

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Articles related to Corneal Edema:

(show top 50)    (show all 236)
idTitleAuthorsYear
1
Transient corneal edema is a predictive factor for pseudophakic cystoid macular edema after uncomplicated cataract surgery. (25646056)
2015
2
Acute corneal edema with subsequent thinning and hyperopic shift following selective laser trabeculoplasty. (25263043)
2014
3
Amantadine induced corneal edema in a patient with primary progressive freezing of gait. (24868424)
2013
4
Pseudophakic/aphakic corneal edema--morphometric predisposing factors analysis based on the fellow eye examination. (23461150)
2012
5
Histological and confocal microscopy changes in chronic corneal edema: implications for endothelial transplantation. (21896863)
2011
6
Determinants of postoperative corneal edema and impact on goldmann intraocular pressure. (21505325)
2011
7
Is excimer laser corneal surgery appropriate after resolution of corneal edema in fuchs dystrophy by descemet membrane endothelial keratoplasty? (20540467)
2011
8
Amantadine-associated corneal edema treated with descemet's stripping automated endothelial keratoplasty. (21158374)
2010
9
Corneal graft detachment without corneal edema after descemet stripping automated endothelial keratoplasty. (20164759)
2010
10
Effect of incident light wavelength and corneal edema on light scattering and penetration: laboratory study of human corneas. (20954687)
2010
11
Amantadine-associated corneal edema. (19486806)
2009
12
Late corneal edema due to retained foldable lens fragment. (19384021)
2009
13
Reversible corneal edema associated with amantadine use: an unrecognized problem. (18785231)
2008
14
Corneal edema after aqueous drainage device implantation. (17571002)
2007
15
Postmarketing surveillance of corneal edema, Fuchs dystrophy, and amantadine use in the Veterans Health Administration. (17893540)
2007
16
The effect of contact lens induced corneal edema on Goldmann applanation tonometry measurements. (17224766)
2007
17
Time to resolution of corneal edema after long-term contact lens wear. (17011862)
2006
18
Permanent corneal edema resulting from the treatment of PTK corneal haze with mitomycin: a case report. (15448508)
2004
19
Corneal edema resolution after "descemetorhexis". (12900257)
2003
20
A case of noninflammatory corneal edema following anterior-posterior radial keratotomy (Sato's operation) successfully treated by topical corticosteroid. (11033131)
2000
21
Effect of diclofenac sodium (Voltaren) on hypoxia-induced corneal edema in humans. (7712610)
1995
22
Corneal edema due to Asclepias curassavica. (7639668)
1995
23
Clinical and pathologic findings of aphakic peripheral corneal edema: Brown-McLean syndrome. (1468222)
1992
24
Therapeutic response of herpes simplex virus-induced corneal edema to trifluridine in combination with immunosuppressive agents. (1907950)
1991
25
Corneal edema after overnight lid closure of rabbits wearing silicone rubber contact lenses. (2019121)
1991
26
Loss of stromal glycosaminoglycans during corneal edema. (2210995)
1990
27
Results of anterior segment reconstruction for aphakic and pseudophakic corneal edema. (3211488)
1988
28
Corneal edema related to accidental Hibiclens exposure. (3400765)
1988
29
Acute corneal edema in pellucid marginal degeneration or acute marginal keratoconus. (3315452)
1987
30
Topical hyperosmolar solutions in the reduction of corneal edema. (3449294)
1987
31
Effect of soft lens power on peripheral corneal edema. (3740206)
1986
32
Fuchs' corneal dystrophy. A clinicopathologic study of the variation in corneal edema. (3526227)
1986
33
Peripheral corneal edema after cataract extraction. (4025488)
1985
34
Critical oxygen levels to avoid corneal edema for daily and extended wear contact lenses. (6592160)
1984
35
The minimum precorneal oxygen tension to avoid corneal edema. (6706510)
1984
36
Corneal edema as a result of ischemic endothelial damage: a case report. (7092039)
1982
37
Corneal edema. (7239818)
1981
38
Corneal edema with hydrogel lenses and eye closure: time course. (7212011)
1981
39
Temporal sequence study of the factors affecting corneal edema associated with soft contact lens wear. (7223850)
1981
40
Vision through an abnormal cornea: a pilot study of the relationship between visual loss from corneal distortion, corneal edema, keratoconus, and some allied corneal pathology. (437949)
1979
41
Acute unilateral central corneal edema. (910866)
1977
42
The effect of corneal edema on visual function. (832964)
1977
43
Anterior chamber scroll and corneal edema. (921153)
1977
44
Corneal edema: iris-clip lens implantation and simple intracapsular extraction compared. (904877)
1977
45
Persistent pupillary membranes and spontaneous corneal edema in a dog. (584602)
1977
46
Corneal edema from hard and hydrogel contact lenses. (1027791)
1976
47
Treatment of chronic corneal edema: summary. (5739741)
1968
48
Corneal edema from a cotton foreign body in the anterior chamber. (5642919)
1968
49
Corneal edema. (15418617)
1949
50
CORNEAL edema; unusual toxic reaction to atabrine. (21007548)
1946

Variations for Corneal Edema

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Expression for genes affiliated with Corneal Edema

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Search GEO for disease gene expression data for Corneal Edema.

Pathways for genes affiliated with Corneal Edema

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Pathways related to Corneal Edema according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6MMP1, MMP3
29.6MMP1, MMP3
39.1IL1B, MMP1, MMP3

Compounds for genes affiliated with Corneal Edema

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Compounds related to Corneal Edema according to GeneCards Suite gene sharing:

(show top 50)    (show all 62)
idCompoundScoreTop Affiliating Genes
1uva 14310.0MMP3, MMP1
2ilomastat4310.0MMP3, MMP1
3latanoprost43 1211.0MMP1, MMP3
4nimesulide43 1211.0MMP1, MMP3
5(4-aminophenyl)mercuric acetate4310.0MMP1, MMP3
6thermolysin4310.0MMP1, MMP3
7uk 3833675910.0MMP3, MMP1
8gi 254023x5910.0MMP3, MMP1
9gm 60015910.0MMP3, MMP1
10sulfonamide4310.0MMP3, MMP1
11hydroxamate439.9MMP3, MMP1
12piroxicam43 1210.9IL1B, MMP3
13levonorgestrel43 59 28 1212.9MMP3, MMP1
14marimastat43 59 1211.9MMP1, MMP3
15clodronate43 49 1211.9MMP1, IL1B
16ethidium bromide439.9MMP3, MMP1
17alendronate43 49 1211.8MMP3, MMP1
18quinacrine43 1210.8MMP1, MMP3
19triptolide439.8MMP3, IL1B
20hematoxylin439.8MMP3, MMP1, KRT8
211,10-phenanthroline43 210.7MMP1, MMP3
22sulfasalazine28 43 49 1212.7MMP3, IL1B
23matrigel439.6KRT8, MMP1, MMP3
24alginate439.6IL1B, MMP3
25lxa4439.5IL1B, MMP1, MMP3
26leflunomide43 49 1211.5IL1B, MMP1, MMP3
27etanercept43 49 1211.5MMP3, MMP1, IL1B
28infliximab43 49 1211.5IL1B, MMP1, MMP3
29ibuprofen43 28 49 24 1213.5MMP3, MMP1, IL1B
30celecoxib43 59 28 49 24 1214.5IL1B, MMP1, MMP3
31pravastatin43 49 28 24 1213.5MMP3, MMP1, IL1B
32mifepristone43 28 59 1212.5IL1B, MMP1, MMP3
33troglitazone43 28 59 1212.5IL1B, MMP1, MMP3
34tgf beta1439.5MMP3, MMP1, IL1B
35ns 39843 5910.5IL1B, MMP1
36hyaluronic acid43 2410.5MMP3, MMP1, IL1B
37curcumin439.5IL1B, MMP1, MMP3
38prostaglandin439.5MMP3, MMP1, IL1B
39methotrexate49 43 1211.5IL1B, MMP1, MMP3
40rantes439.4MMP3, MMP1, IL1B
41ribonucleic acid439.4IL1B, MMP1, MMP3
42n acetylcysteine439.4MMP3, MMP1, IL1B
43indomethacin43 28 59 1212.4IL1B, MMP1, MMP3
44sb 20358043 5910.3MMP3, MMP1, IL1B
45ndga439.2IL1B, MMP3
46genistein43 28 59 2 24 1214.2MMP3, MMP1, IL1B, KRT8
47cycloheximide439.2KRT8, IL1B, MMP1, MMP3
48vegf439.1KRT8, IL1B, MMP1, MMP3
49pd 98,059439.1IL1B, MMP1, MMP3
50retinoic acid43 249.7MMP3, MMP1, IL1B, KRT8

GO Terms for genes affiliated with Corneal Edema

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Biological processes related to Corneal Edema according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1collagen catabolic processGO:00305749.6MMP1, MMP3

Products for genes affiliated with Corneal Edema

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Sources for Corneal Edema

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet