Aliases & Classifications for Corneal Ulcer

MalaCards integrated aliases for Corneal Ulcer:

Name: Corneal Ulcer 12 52 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:8463
ICD10 33 H16.0 H16.00
ICD9CM 35 370.0 370.00
MeSH 42 D003320
NCIt 47 C50515
UMLS 69 C0010043

Summaries for Corneal Ulcer

MalaCards based summary : Corneal Ulcer is related to ectropion and keloids. An important gene associated with Corneal Ulcer is NGF (Nerve Growth Factor), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Miconazole and Natamycin have been mentioned in the context of this disorder. Affiliated tissues include eye, thyroid and testes, and related phenotypes are hematopoietic system and immune system

Wikipedia : 72 Corneal ulcer, or ulcerative keratitis, is an inflammatory or more seriously, infective condition of the... more...

Related Diseases for Corneal Ulcer

Diseases in the Corneal Ulcer family:

Central Corneal Ulcer

Diseases related to Corneal Ulcer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 145)
id Related Disease Score Top Affiliating Genes
1 ectropion 30.3 CCR1 MMP9
2 keloids 29.5 IL1B MMP3
3 influenza 25.1 CCL11 CCR1 CCR3 DHX9 IL1B MMP2
4 perforated corneal ulcer 12.1
5 central corneal ulcer 12.1
6 mycotic corneal ulcer 12.0
7 marginal corneal ulcer 12.0
8 ring corneal ulcer 12.0
9 dacryocystitis 11.1
10 corneal dystrophy, lattice type i 10.8
11 tyrosinemia, type ii 10.8
12 lymphedema-distichiasis syndrome 10.8
13 barre-lieou syndrome 10.8
14 ichthyosis follicularis atrichia photophobia syndrome 10.8
15 neurotrophic keratopathy 10.8
16 facial arteriovenous malformation 10.6 MMP2 MMP9
17 familial short qt syndrome 10.6 MMP2 MMP9
18 leucocyte adhesion defect 10.6 MMP2 MMP9
19 acquired hemangioma 10.6 MMP2 MMP9
20 transitional meningioma 10.6 MMP2 MMP9
21 drug rash with eosinophilia and systemic symptoms 10.6 MMP2 MMP9
22 tinea profunda 10.6 MMP2 MMP9
23 xanthogranulomatous cholecystitis 10.6 MMP2 MMP9
24 collagenous colitis 10.6 MMP2 MMP9
25 sialadenitis 10.6 MMP2 MMP9
26 toxic optic neuropathy 10.6 IL1B MMP9
27 corneal staphyloma 10.6 MMP2 MMP9
28 limbic encephalitis 10.6 MMP2 MMP9
29 spindle epithelial tumor with thymus-like differentiation tumor 10.6 MMP2 MMP9
30 nasal cavity adenocarcinoma 10.6 MMP2 MMP9
31 ulnar neuropathy 10.6 MMP2 MMP9
32 colon squamous cell carcinoma 10.5 MMP2 MMP9
33 oligomeganephronic renal hypoplasia 10.5 MMP2 MMP9
34 tricho onychic dysplasia 10.5 MMP2 MMP9
35 lower clivus meningioma 10.5 IL1B MMP9
36 lung papillary adenocarcinoma 10.5 MMP2 MMP9
37 tinea favosa 10.5 IL1B NGF
38 ileocolitis 10.5 IL1B NGF
39 solitary cyst of breast 10.5 CCL11 MMP9
40 breast adenomyoepithelioma 10.5 IL1B MMP9
41 dioctophymiasis 10.5 CCL11 MMP9
42 keratomalacia 10.4
43 epididymis adenocarcinoma 10.4 CCL11 MMP9
44 chronic cholangitis 10.4 CCL11 MMP9
45 rare endometriosis 10.4 MMP2 MMP9
46 ribbing disease 10.4 MMP3 MMP9
47 laryngostenosis 10.4 MMP2 MMP9
48 childhood endodermal sinus tumor 10.4 MMP3 MMP9
49 benign familial infantile epilepsy 10.4 IL1B NGF
50 viljoen kallis voges syndrome 10.4 CCL11 MMP9

Comorbidity relations with Corneal Ulcer via Phenotypic Disease Network (PDN):


Bullous Keratopathy Cicatricial Pemphigoid
Hypertension, Essential Hypopyon Ulcer
Perforated Corneal Ulcer Purulent Endophthalmitis

Graphical network of the top 20 diseases related to Corneal Ulcer:



Diseases related to Corneal Ulcer

Symptoms & Phenotypes for Corneal Ulcer

MGI Mouse Phenotypes related to Corneal Ulcer:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.76 CCL11 CCR1 CCR3 DHX9 IL1B MMP2
2 immune system MP:0005387 9.56 MMP9 CCL11 CCR1 CCR3 DHX9 IL1B
3 respiratory system MP:0005388 9.02 CCL11 CCR1 CCR3 MMP2 MMP9

Drugs & Therapeutics for Corneal Ulcer

Drugs for Corneal Ulcer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 177)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 22916-47-8 4189
2
Natamycin Approved Phase 4,Phase 3,Phase 1,Phase 2 7681-93-8 5281099
3
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
4
Moxifloxacin Approved, Investigational Phase 4,Phase 3,Phase 2 354812-41-2, 151096-09-2 152946
5
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
6
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
7
Ephedrine Approved Phase 4,Phase 3,Phase 1,Phase 2 299-42-3 9294
8
Pseudoephedrine Approved Phase 4,Phase 3,Phase 1,Phase 2 90-82-4 7028
9
Amphotericin B Approved, Investigational Phase 4 1397-89-3 14956 5280965
10
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741 24759
11
Riboflavin Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 83-88-5 493570
12 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1
13 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 1
14 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1
15 Antifungal Agents Phase 4,Phase 3,Phase 1,Phase 2
16 Autonomic Agents Phase 4,Phase 3,Phase 1,Phase 2
17 Hormone Antagonists Phase 4,Phase 3,Phase 1,Phase 2
18 Hormones Phase 4,Phase 3,Phase 1,Phase 2
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 1,Phase 2
20 Ophthalmic Solutions Phase 4,Phase 3,Phase 2,Phase 1
21 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2
22 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
23 Respiratory System Agents Phase 4,Phase 3,Phase 1,Phase 2
24 Tetrahydrozoline Phase 4,Phase 3,Phase 2,Phase 1
25 Vasoconstrictor Agents Phase 4,Phase 3,Phase 1,Phase 2
26 Anti-Infective Agents, Local Phase 4,Phase 3,Phase 2,Phase 1
27 Antiparasitic Agents Phase 4,Phase 2,Phase 3
28 Antiprotozoal Agents Phase 4,Phase 2,Phase 3
29 Anesthetics Phase 4,Phase 3,Phase 1
30 Anesthetics, Local Phase 4,Phase 3
31 Central Nervous System Depressants Phase 4,Phase 3
32 Protective Agents Phase 4,Phase 3,Phase 2
33 Mitogens Phase 4,Phase 2,Phase 1
34 Methylprednisolone acetate Phase 4,Phase 3
35 Methylprednisolone Hemisuccinate Phase 4,Phase 3
36 Norgestimate, ethinyl estradiol drug combination Phase 4,Phase 3,Phase 2
37 Prednisolone acetate Phase 4,Phase 3
38 Prednisolone hemisuccinate Phase 4,Phase 3
39 Prednisolone phosphate Phase 4,Phase 3
40 Antiemetics Phase 4,Phase 3
41 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
42 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
43 Antirheumatic Agents Phase 4,Phase 2,Phase 1
44 BB 1101 Phase 4
45 Calcineurin Inhibitors Phase 4
46 Cyclosporins Phase 4,Phase 1
47 Dermatologic Agents Phase 4,Phase 1,Phase 2
48 Dexamethasone acetate Phase 4 1177-87-3
49 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
50 glucocorticoids Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 66)

id Name Status NCT ID Phase Drugs
1 Steroids for Corneal Ulcers Trial Completed NCT00324168 Phase 4 Antibiotics;Topical corticosteroid;Placebo
2 Topical Cyclosporine for Vernal Keratoconjunctivitis (VKC) in Rwanda Completed NCT01211327 Phase 4 Cyclosporine A;Dexamethasone
3 Cross-linking for Corneal Ulcers Treatment Trial Recruiting NCT02570321 Phase 4
4 Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease Recruiting NCT01738243 Phase 4 Hyaluronic Acid Gel injection;Saline injection
5 Efficacy and Safety of Plasma Rich in Growth Factors (PRGF-Endoret) Eye-drops in the Treatment of Neurotrophic Keratitis Not yet recruiting NCT02707120 Phase 4 PRGF-Endoret;Artificial tears eye-drops
6 Low Dose Doxycycline in the Treatment of Corneal Burn Unknown status NCT01886560 Phase 2, Phase 3 Doxycycline;Placebo
7 Mycotic Ulcer Treatment Trial I Completed NCT00996736 Phase 3 Natamycin;Voriconazole
8 The Mycotic Ulcer Treatment Trial II: A Randomized Trial Comparing Oral Voriconazole vs Placebo Completed NCT00997035 Phase 3 Voriconazole;Placebo
9 Comparison Between Bandage Contact Lens and Pressure Patching for The Erosion Area and Pain Scale in Corneal Erosion Patients Completed NCT01809483 Phase 3
10 Efficacy and Safety Assessment of T4020 Versus Vehicule in Patients With Chronic Neurotrophic Keratitis or Corneal Ulcer Recruiting NCT01794312 Phase 3
11 Swiss PACK-CXL Multicenter Trial for the Treatment of Infectious Keratitis Recruiting NCT02717871 Phase 3 Cefazolin in combination with either tobramycin or gentamicin;Cycloplegic agents (cyclopentolate 1% eye drops);Fluoroquinolones (Besifloxacin ; ciprofloxacin ; gatifloxacin ; levofloxacin ; moxifloxacin ; ofloxacin );Corticosteroids (prednisolone acetate 0.5% or 1% eye drops)
12 Effectiveness of Corneal Accelerated Crosslinking for Infectious Keratitis Recruiting NCT02865876 Phase 3
13 Treating Dry Eyes and Corneal Ulcers With Fingerprick Autologous Blood Enrolling by invitation NCT02153515 Phase 3
14 Mycotic Antimicrobial Localized Injection for Treatment of Corneal Ulcers Enrolling by invitation NCT02731638 Phase 3 Intrastromal voriconazole;Natamycin
15 A Clinical Trial of the Treatment of Fungal Corneal Ulcers With Povidone-Iodine Terminated NCT00516399 Phase 3 povidone-iodine 1.25% ophthalmic solution;natamycin ophthalmic suspension, USP 5%
16 Effect of Tetracaine on Pain Management and Corneal Healing in Patients With Acute Corneal Abrasion Terminated NCT02483897 Phase 3 Tetracaine 0.5% ophthalmic drops;Normal Saline placebo drops
17 Assessment of Tear Film Thickness by Optical Coherence Tomography in Healthy Subjects and Subjects With Dry Eye Disease Withdrawn NCT01753596 Phase 3
18 Evaluation of Efficacy of 20 µg/ml rhNGF New Formulation (With Anti-oxidant) in Patients With Stage 2 and 3 Neurotrophic Keratitis Unknown status NCT02227147 Phase 2 rhNGF 20µg/ml;Placebo Vehicle
19 A Clinical Trial of Povidone-Iodine for the Treatment of Bacterial Corneal Ulcers Completed NCT00386958 Phase 2 Povidone-Iodine
20 Safety and Efficacy Study of Gatifloxacin Compared With Ciprofloxacin in Patients With Acute Bacterial Corneal Ulcers Completed NCT00651586 Phase 2 Gatifloxacin 0.3% ophthalmic solution;Ciprofloxacin 0.3% ophthalmic solution
21 Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis. Completed NCT01756456 Phase 1, Phase 2 rhNGF 10 µg/ml eye drops solution;rhNGF 20 µg/ml eye drops solution;Placebo
22 Therapeutic Exploratory Study of Comparing Natamycin and Voriconazole to Treat Fungal Corneal Ulcer Completed NCT00557362 Phase 1, Phase 2 Natamycin 5%;Voriconazole
23 Collagen Cross-linking in Infectious Keratitis Trial Completed NCT01831206 Phase 2
24 Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye Completed NCT01393132 Phase 2 Thymosin Beta 4 eye drops;Vehicle Control
25 Use of Cross-linked Donor Corneas as Carriers for the Boston Keratoprosthesis Completed NCT01582880 Phase 1, Phase 2 Riboflavin
26 Evaluation and Treatment of Eye Complications of Vaccinia Vaccination Completed NCT00081835 Phase 2 NP-016 Vaccine Immune Globulin (IV-VIG)
27 NSAID Phase II for Non-central Involved Diabetic Macular Edema (DME) Completed NCT01331005 Phase 2 nepafenac 0.1% drops
28 Allogeneic Tissue Engineering (Nanostructured Artificial Human Cornea) in Patients With Corneal Trophic Ulcers in Advanced Stages, Refractory to Conventional (Ophthalmic) Treatment Recruiting NCT01765244 Phase 1, Phase 2
29 Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting Recruiting NCT03041883 Phase 1, Phase 2
30 Autologous Platelet Lysate in Corneal Epithelial Defects Recruiting NCT02979912 Phase 1, Phase 2
31 Cyclophosphamide vs. Infliximab for Refractory Idiopathic Scleritis (CIRIS) Not yet recruiting NCT03088293 Phase 2 Infliximab;Cyclophosphamide
32 A Comparison of Three Fluoroquinolone Topical Eyedrops in the Treatment of Infectious Corneal Ulcers. Terminated NCT01928693 Phase 2 Besivance 0.6% Ophthalmic Suspension;Zymaxid 0.5% Ophthalmic Solution;Vigamox 0.5% Ophthalmic Solution
33 Infliximab to Improve Retention of the Boston Keratoprosthesis in Patients After Stevens Johnson Syndrome/ Toxic Epidermal Necrolysis (SJS/TENS) Withdrawn NCT01256489 Phase 1, Phase 2 Infliximab
34 Safety and Effectiveness of the UV-X System for Corneal Collagen Cross-Linking in Eyes With Refractory Corneal Infection Completed NCT02068430 Phase 1 Riboflavin 0.1%
35 Topical Autologous Serum Application for the Treatment of Corneal Epithelium Defect After Ocular Surgeries Completed NCT01075347 Phase 1
36 Topical Autologous Insulin Application for the Treatment of Corneal Epithelium Defect After Ocular Surgeries Completed NCT01031888 Phase 1 Topical insulin eye drops;Conventional postoperative eye drops
37 Screening Aid to Identify Corneas That May Have Pathologies or Other Conditions Completed NCT00396188 Phase 1
38 Topical Infliximab for Sterile Corneal Melt Recruiting NCT02987686 Phase 1 Topical Infliximab
39 Stem Cells for Corneal Haze Recruiting NCT03295292 Phase 1
40 Xenogenic Keratoplasty From Porcine Cornea Suspended NCT01443559 Phase 1
41 The Application of Fibrin Glue in Ocular Surface Diseases Withdrawn NCT00155402 Phase 1 tissue fibrin glue application (Tisseel)
42 Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory Conditions Withdrawn NCT02042027 Phase 1 Gamunex-C
43 Transplantation of Acellular Corneal Matrix to Treat Corneal Ulcer Unknown status NCT01244776
44 Painless Subconjunctival Antibiotic and Antifungal Injection in Corneal Ulcer Patients Unknown status NCT00789646
45 Clinical & Visual Outcomes of Collagen Cross Linking for Fungal Keratitis Unknown status NCT02328053 Topical anti-fungal therapy
46 The Asia Cornea Society Infectious Keratitis Study Unknown status NCT01560208
47 Prevalence of Decreased Corneal Sensation in Patients With Chronic Inflammatory Demyelinating Polyneuropathy Unknown status NCT01379833
48 Pascal Pascal Dynamic Contour Tonometer (DCT) Intraocular Pressure and Ocular Pulse Amplitude in Patients With Thyroid Related Orbitopathy: A Comparison to Goldmann Tonometer and to Muscles Characteristics on CT Scan Unknown status NCT00646295
49 Safety and Effectiveness of Collagen-phosphorylcholine Bioengineered Cornea in Patients Requiring Lamellar Keratoplasty Completed NCT02277054
50 Randomized Double Blinded Study Evaluating CACICOL20 Efficiency Versus Placebo Corneal Chronic Ulcers Healing Completed NCT01242839

Search NIH Clinical Center for Corneal Ulcer

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: corneal ulcer

Genetic Tests for Corneal Ulcer

Anatomical Context for Corneal Ulcer

MalaCards organs/tissues related to Corneal Ulcer:

39
Eye, Thyroid, Testes, Liver, Bone

Publications for Corneal Ulcer

Articles related to Corneal Ulcer:

(show top 50) (show all 356)
id Title Authors Year
1
Management of a Nonhealing, Superficial Corneal Ulcer in a Hyacinth Macaw (Anodorhynchus hyacinthinus). ( 28891697 )
2017
2
Treatment Results of Corneal Collagen Cross-Linking Combined with Riboflavin and 440 Nm Blue Light for Bacterial Corneal Ulcer in Rabbits. ( 28644681 )
2017
3
Corneal ulcer due to a rare coelomycetes fungus Chaetomium strumarium: Case report and global review of Chaetomium keratomycosis. ( 28905835 )
2017
4
Treatment of a Perforated Corneal Ulcer with Tectonic DSAEK: a Case Report. ( 28282693 )
2017
5
Risk of corneal ulcer in patients with end-stage renal disease: a retrospective large-scale cohort study. ( 28855193 )
2017
6
CYP1B1 Cytopathy: Uncommon Phenotype of a Homozygous CYP1B1 Deletion as Internal Corneal Ulcer of Von Hippel. ( 28644236 )
2017
7
An unusual case of spontaneous Mycobacterium chelonae corneal ulcer in a healthy middle-aged adult [Retraction]. ( 28769591 )
2017
8
The Utility of Repeat Culture in Fungal Corneal Ulcer Management: A Secondary Analysis of the MUTT-I Randomized Clinical Trial. ( 28385473 )
2017
9
Corneal ulcer due to a rare pleosporalean member of the genus Bipolaris following cow tail injury to the eye: A case report and review of literature. ( 28573998 )
2017
10
Painful Acute Corneal Ulceration and Anterior Stromal Keratitis in an Adolescent With Reactive Arthritis. ( 27977029 )
2016
11
An unusual case of spontaneous Mycobacterium chelonae corneal ulcer in a healthy middle-aged adult. ( 27274315 )
2016
12
Management of Infective Corneal Ulcer: Epidemiology Needs To Be Evaluated As Priority Basis. ( 27612884 )
2016
13
Acacia honey accelerates in vitro corneal ulcer wound healing model. ( 27473120 )
2016
14
Outcome of Urgent Penetrating Keratoplasty for Corneal Ulcer at Thammasat University Hospital. ( 27455827 )
2016
15
Spontaneous Corneal Hydrops in a Patient with a Corneal Ulcer. ( 26889160 )
2016
16
Orbital cellulitis and corneal ulcer due to Cedecea: First reported case and review of the literature. ( 27070554 )
2016
17
Corneal Ulcer Leading to Evisceration or Enucleation in a Tertiary Eye Care Center in Thailand: Clinical and Microbiological Characteristics. ( 27266225 )
2016
18
Bacterial corneal ulcer associated with common variable immune deficiency. ( 27491761 )
2016
19
Acquired anterior staphyloma after corneal ulcer associated with the use of crack. ( 27626156 )
2016
20
Fungal keratitis in patients with corneal ulcer attending Minilik II Memorial Hospital, Addis Ababa, Ethiopia. ( 27576913 )
2016
21
Diagnosis and Treatment of Pythium Insidiosum Corneal Ulcer in a Chinese Child: A Case Report and Literature Review. ( 28025573 )
2016
22
Microbiological profile of corneal ulcer cases diagnosed in a tertiary care ophthalmological institute in Nepal. ( 27899093 )
2016
23
A Novel Tectonic Keratoplasty with Femtosecond Laser Intrastromal Lenticule for Corneal Ulcer and Perforation. ( 27453231 )
2016
24
Rare case of bilateral perforated corneal ulcer due to gonococcal infection, managed with temporary periosteal graft. ( 26907819 )
2016
25
Corneal ulcer? Think beyond only a bacterial etiology. ( 25609872 )
2015
26
Treatment of Acanthamoeba neurotrophic corneal ulcer with topical matrix therapy. ( 26101555 )
2015
27
Long-term efficacy of glycerine-processed amniotic membrane transplantation in patients with corneal ulcer. ( 25773445 )
2015
28
Community practice patterns for bacterial corneal ulcer evaluation and treatment. ( 25536529 )
2015
29
Pink hypopyon in a patient with Serratia marcescens corneal ulceration. ( 25861400 )
2015
30
Bilateral sterile perforated corneal ulcer in an HIV case. ( 26265852 )
2015
31
Alpha-1-antitrypsin associated panniculitis and corneal ulcer with a rare allelic variant (PiFZ): a case report. ( 26474730 )
2015
32
Night market contact lens-related corneal ulcer: Should we increase public awareness? ( 26425295 )
2015
33
Epidemiological Aspect and common Bacterial and Fungal isolates from Suppurative Corneal Ulcer in Mymensingh Region. ( 26007250 )
2015
34
Experimental study on cryotherapy for fungal corneal ulcer. ( 25880872 )
2015
35
In vitro susceptibility of filamentous fungal isolates from a corneal ulcer clinical trial. ( 24439440 )
2014
36
Simultaneous study of matrix metalloproteinases, proinflammatory cytokines, and soluble cytokine receptors in the tears of noninfectious corneal ulcer patients. ( 25005620 )
2014
37
Cunninghamella spinosum fungal corneal ulcer- first case report. ( 24722275 )
2014
38
The corneal ulcer one-touch study: a simplified microbiological specimen collection method. ( 25244977 )
2014
39
Complementary treatment of contact lens-induced corneal ulcer using honey: A case report. ( 25278429 )
2014
40
In Vitro Antibiotic Susceptibility of Pseudomonas aeruginosa Corneal Ulcer Isolates. ( 24564536 )
2014
41
Antibiotic susceptibility pattern of bacteria isolated from corneal ulcer in a tertiary level eye hospital. ( 26402978 )
2014
42
Corneal ulcer caused by nocardia brasiliensis in a patient with diabetes. ( 24790888 )
2014
43
Acinetobacter junii as an aetiological agent of corneal ulcer. ( 25056128 )
2014
44
Repositioning of pedicle conjunctival flap performed for refractory corneal ulcer. ( 24669154 )
2014
45
Ultraviolet A and riboflavin therapy as an adjunct in corneal ulcer refractory to medical treatment. ( 24172067 )
2013
46
Bilateral corneal ulceration in ocular graft-versus-host disease. ( 24204119 )
2013
47
A clinical microbiological study of corneal ulcer patients at western Gujarat, India. ( 23852845 )
2013
48
Fungal corneal ulcer and bacterial orbital cellulitis occur as complications of bacterial endophthalmitis after cataract surgery in an immunocompetent patient. ( 23448560 )
2013
49
Evaluation of risk factors for development of corneal ulcer after nonocular surgery in dogs: 14 cases (2009-2011). ( 23683020 )
2013
50
An environmental Sporothrix as a cause of corneal ulcer. ( 24432225 )
2013

Variations for Corneal Ulcer

Expression for Corneal Ulcer

Search GEO for disease gene expression data for Corneal Ulcer.

Pathways for Corneal Ulcer

Pathways related to Corneal Ulcer according to GeneCards Suite gene sharing:

(show all 25)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.74 CCL11 CCR1 DHX9 IL1B MMP2 MMP3
2
Show member pathways
13.14 CCL11 CCR1 CCR3 IL1B NGF
3
Show member pathways
13.05 CCL11 CCR1 CCR3 MMP2 MMP3 MMP9
4
Show member pathways
13.01 CCL11 CCR1 CCR3 IL1B NGF
5
Show member pathways
12.99 CCL11 CCR1 IL1B MMP2 MMP3 MMP9
6
Show member pathways
11.96 CCL11 IL1B MMP3 MMP9
7 11.86 IL1B MMP2 MMP9
8
Show member pathways
11.79 CCL11 CCR1 CCR3
9 11.73 MMP2 MMP3 MMP9
10 11.7 IL1B MMP3 MMP9
11
Show member pathways
11.65 MMP2 MMP3 MMP9
12 11.57 MMP2 MMP3 MMP9
13 11.41 CCL11 IL1B MMP2 MMP3 MMP9
14 11.33 MMP2 MMP3 MMP9
15 11.31 CCR1 IL1B
16 11.3 MMP2 MMP9
17
Show member pathways
11.26 MMP2 MMP9
18
Show member pathways
11.26 IL1B MMP2 MMP3 MMP9
19 11.2 MMP3 MMP9
20 11.12 MMP2 MMP9
21 11.12 MMP2 MMP9
22 10.98 MMP2 MMP9
23 10.97 MMP2 MMP9
24 10.83 CCR3 IL1B MMP9
25 10.82 CCL11 CCR3 IL1B MMP2 MMP9

GO Terms for Corneal Ulcer

Cellular components related to Corneal Ulcer according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 CCL11 IL1B MMP2 MMP3 MMP9 NGF

Biological processes related to Corneal Ulcer according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 chemotaxis GO:0006935 9.63 CCL11 CCR1 CCR3
2 positive regulation of angiogenesis GO:0045766 9.61 CCL11 CCR3 IL1B
3 extracellular matrix disassembly GO:0022617 9.54 MMP2 MMP3 MMP9
4 endodermal cell differentiation GO:0035987 9.52 MMP2 MMP9
5 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.51 MMP2 MMP9
6 chemokine-mediated signaling pathway GO:0070098 9.5 CCL11 CCR1 CCR3
7 collagen catabolic process GO:0030574 9.43 MMP2 MMP3 MMP9
8 positive regulation of cell migration GO:0030335 9.33 CCL11 CCR1 MMP9
9 positive regulation of interleukin-6 secretion GO:2000778 9.19 IL1B
10 positive regulation of innate immune response GO:0045089 9.18 MMP2
11 embryo implantation GO:0007566 9.13 IL1B MMP2 MMP9
12 regulation of defense response to virus by host GO:0050691 9.1 IL1B
13 inflammatory response GO:0006954 8.92 CCL11 CCR1 CCR3 IL1B

Molecular functions related to Corneal Ulcer according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 9.54 MMP2 MMP3 MMP9
2 metallopeptidase activity GO:0008237 9.5 MMP2 MMP3 MMP9
3 metalloendopeptidase activity GO:0004222 9.33 MMP2 MMP3 MMP9
4 chemokine receptor activity GO:0004950 9.26 CCR1 CCR3
5 C-C chemokine receptor activity GO:0016493 8.96 CCR1 CCR3
6 C-C chemokine binding GO:0019957 8.62 CCR1 CCR3

Sources for Corneal Ulcer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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