MCID: CRN006
MIFTS: 47

Coronary Aneurysm malady

Summaries for Coronary Aneurysm

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63Wikipedia, 32MalaCards
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Wikipedia:63 Coronary artery aneurysm is an abnormal dilatation of part of the coronary artery. more...

MalaCards: Coronary Aneurysm, also known as arteriovenous aneurysm of coronary vessels, is related to kawasaki disease and myocardial infarction. An important gene associated with Coronary Aneurysm is LTA (lymphotoxin alpha), and among its related pathways are RIP-mediated NFkB activation via ZBP1 and Transcription NF-kB signaling pathway. The compounds prednisolone and pentoxifylline have been mentioned in the context of this disorder. Affiliated tissues include heart, lymph node and kidney, and related mouse phenotype respiratory system.

Aliases & Classifications for Coronary Aneurysm

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH, 27ICD9CM
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Aliases & Descriptions:

coronary aneurysm 8 10 60
arteriovenous aneurysm of coronary vessels 8
aneurysmal lesion of coronary artery 8
aneurysm of coronary vessels 8


External Ids:

Disease Ontology8 DOID:3362
MeSH34 D003323
SNOMED-CT56 373139003, 50570003
ICD9CM27 414.11

Related Diseases for Coronary Aneurysm

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Coronary Aneurysm:



Diseases related to coronary aneurysm

Clinical Features for Coronary Aneurysm

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Drugs & Therapeutics for Coronary Aneurysm

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Coronary Aneurysm

Drug clinical trials:

Search ClinicalTrials for Coronary Aneurysm

Search NIH Clinical Center for Coronary Aneurysm

Search CenterWatch for Coronary Aneurysm

Genetic Tests for Coronary Aneurysm

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Anatomical Context for Coronary Aneurysm

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32MalaCards
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MalaCards organs/tissues related to Coronary Aneurysm:

32
Heart, Lymph node, Kidney, T cells, Endothelial, Lung, Prostate, Trachea

Animal Models for Coronary Aneurysm or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Coronary Aneurysm:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.4LDB3, IL10, LTA, TNF

Publications for Coronary Aneurysm

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50PubMed
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Articles related to Coronary Aneurysm:

(show top 50)    (show all 756)
idTitleAuthorsYear
1
Giant coronary artery aneurysm after takeuchi repair for anomalous left coronary artery from the pulmonary artery. (24169018)
2014
2
Coronary aneurysm mimicking a five chamber heart. (23733440)
2014
3
Giant coronary artery aneurysm. (23230818)
2013
4
Combined transdiaphragmatic off-pump and minimally invasive coronary artery bypass with right gastroepiploic artery and abdominal aortic aneurysm repair. (23997852)
2013
5
Aortic aneurysm: an independent predictor of a looped brachiocephalic trunk in patients undergoing transradial coronary angiography. (23921234)
2013
6
Myocardial infarction in a 17-year-old patient due to neurofibromatosis-associated coronary aneurysm. (22813835)
2013
7
An extremely large coronary aneurysm associated with a quadricuspid aortic valve in an adult patient. (23318855)
2013
8
Ruptured aneurysm of the right coronary sinus of Valsalva in a child with Down syndrome. (23594487)
2013
9
Sudden death as a late sequel of Kawasaki disease: postmortem CT demonstration of coronary artery aneurysm. (22673706)
2013
10
Congenital left main coronary artery aneurysm. (21803604)
2012
11
Polyarteritis nodosa complicated by chronic total occlusion accompanying aneurysms on all coronary arteries. (22977455)
2012
12
Combination therapy involving stenting and coil embolization for atherosclerotic narrowing complicated by a coronary aneurysm. (21805560)
2012
13
Giant coronary artery aneurysm with coronary arteriovenous fistula draining into the coronary sinus. (21678126)
2011
14
Myocardial bridging with a coronary artery aneurysm and left ventricular stunning. (21613937)
2011
15
Case images: noninvasive evaluation of a giant circumflex coronary artery aneurysm fistulized into the coronary sinus by multislice computed tomography. (21358241)
2011
16
Histopathologic Characteristics of a Coronary-pulmonary Artery Fistula with a Coronary Artery Aneurysm. (23555427)
2011
17
Long-term prognosis of patients with Kawasaki disease complicated by giant coronary aneurysms: a single-institution experience. (21502578)
2011
18
Covered stents in giant coronary artery aneurysm. (20675659)
2010
19
Drug eluting stent induced coronary artery aneurysm repair by exclusion. Where are we headed? (19464920)
2009
20
Giant left anterior descending coronary artery aneurysm. (17395300)
2008
21
Coronary artery aneurysm: a review and hypothesis regarding etiology. (18466032)
2008
22
Dense smoke in the operating room: epivascular ultrasonography in a large right coronary artery aneurysm. (18422660)
2008
23
Metabolic syndrome and the risk of new vascular events and all-cause mortality in patients with coronary artery disease, cerebrovascular disease, peripheral arterial disease or abdominal aortic aneurysm. (18199567)
2008
24
Giant right coronary artery aneurysm presenting as a paracardiac mass. (18402794)
2008
25
Cardiac tamponade due to rupture of coronary artery fistulas with a giant aneurysm containing a free floating ball thrombus: a case report. (17685030)
2007
26
Surgical treatment of a giant coronary artery aneurysm: a modified approach. (17889012)
2007
27
Successful surgical treatment of an infected right coronary artery aneurysm-to-right ventricle fistula after sirolimus-eluting stent implantation. (17575380)
2007
28
Unruptured left main coronary artery aneurysm presented with acute cerebral infarction. (17307764)
2007
29
Giant coronary artery aneurysm in Behcet's disease. (17933996)
2007
30
Ruptured cerebral aneurysm and acute coronary artery dissection in the setting of multivascular fibromuscular dysplasia: a case report. (18216385)
2007
31
Incidental echocardiographic detection of coronary artery aneurysm in a patient with multiple vascular aneurysms. (15053789)
2004
32
Left main coronary artery aneurysm associated with severe atherosclerosis: a case report from Pakistan. (16104496)
2004
33
Percutaneous sealing of coronary aneurysm by grafted stent implantation. (15486128)
2004
34
Coronary artery aneurysm and type-A aortic dissection demonstrated by retrospectively ECG-gated multislice spiral CT. (11868099)
2002
35
Clinical features and outcome of coronary artery aneurysm in patients with acute myocardial infarction undergoing a primary percutaneous coronary intervention. (12417812)
2002
36
New stent design for autologous venous graft-covered stent preparation: first human application for sealing of a coronary aneurysm. (11835652)
2002
37
One-stage thoracic aortic aneurysm treatment and coronary artery bypass grafting. (11355257)
2001
38
Coronary artery aneurysm after stent implantation. (10481393)
1999
39
Sealing of coronary artery aneurysm by using a new stent graft. (10467081)
1999
40
High incidence of angiotensin I converting enzyme genotype II in Kawasaki disease patients with coronary aneurysm. (9128808)
1997
41
Percutaneous transcatheter repair of a coronary aneurysm using a composite autologous cephalic vein-coated Palmaz-Schatz biliary stent. (7484850)
1995
42
Congenital coronary artery fistula--surgical results and late changes in coronary artery aneurysm. (8788369)
1995
43
Detection of Epstein-Barr virus DNA in cardiac and aortic tissues from chronic, active Epstein-Barr virus infection associated with Kawasaki disease-like coronary artery aneurysms. (8391571)
1993
44
Coronary artery aneurysm formation following directional coronary atherectomy. (1446330)
1992
45
Vasospasm in a coronary artery aneurysm. (1901244)
1991
46
Giant coronary aneurysm associated with aortic mucoid medionecrosis. (2054303)
1991
47
Coronary artery aneurysm formation following percutaneous transluminal coronary angioplasty: treatment of associated restenosis with repeat percutaneous transluminal coronary angioplasty. (2354519)
1990
48
Surgical treatment of coronary aneurysm developed after PTCA. (2967559)
1988
49
Immobile right aortic leaflet in a case of the aortitis syndrome complicated by a left coronary sinus aneurysm. (3841908)
1985
50
Mucocutaneous lymph node syndrome with coronary artery aneurysm. (7133)
1976

Genetic Variations for Coronary Aneurysm

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Expression for genes affiliated with Coronary Aneurysm

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Coronary Aneurysm

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Pathways for genes affiliated with Coronary Aneurysm

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Sources:
53Reactome, 51QIAGEN, 12EMD Millipore, 37NCBI BioSystems Database, 29KEGG, 52R&D Systems
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Compounds for genes affiliated with Coronary Aneurysm

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44Novoseek, 28IUPHAR, 11DrugBank, 49PharmGKB, 59Tocris Bioscience, 24HMDB
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Compounds related to Coronary Aneurysm according to GeneCards/GeneDecks:

(show all 49)
idCompoundScoreTop Affiliating Genes
1prednisolone44 28 1112.5LTA
2pentoxifylline44 1111.5LTA
3ivig4410.5GPT
4d-galactosamine449.9TNF, GPT
5nash449.9GPT, TNF
6cdp571449.7IL10, TNF
7interferon gamma449.7TNF, IL10
86 mercaptopurine449.7IL10, GPT
9blys449.7IL10, TNF
10mip 1alpha449.7TNF, IL10
11natalizumab44 1110.7IL10, TNF
12adalimumab44 49 1111.7TNF, IL10
135 aminosalicylic acid449.7IL10, TNF
14il-12449.7IL10, TNF
15fenofibrate44 49 1111.6TNF, GPT
16imiquimod44 28 59 1112.6TNF, IL10
17polymyxin b449.6IL10, TNF
18risperidone28 44 49 59 11 2414.6GPT, IL10
19groalpha449.6TNF, IL10
20gm-csf44 2810.6IL10, TNF
21mycophenolate mofetil44 49 1111.6GPT, IL10
228-isoprostane449.6IL10, TNF
23polyinosinic-polycytidylic acid449.6TNF, IL10
24tarc449.5TNF, IL10
25carbamazepine44 49 1111.4LTA, TNF
26ribavirin44 49 1111.4IL10, GPT
27peptidoglycan44 2810.4IL10, TNF
28ifn-alpha449.4GPT, IL10
29thyroxine44 2410.4GPT, IL10, LTA
30toxin-1449.4IL10, LTA, TNF
31okt3449.4IL10, LTA, TNF
32lipoteichoic acid449.4IL10, LTA, TNF
33etanercept44 49 1111.4IL10, LTA, TNF
34il 10449.4TNF, LTA, IL10
35infliximab44 49 1111.3IL10, LTA, TNF
36tgf beta1449.3IL10, LTA, TNF
372,5-oligoadenylate449.3TNF, IL10, GPT
38ionomycin449.3TNF, LTA, IL10
39calcitriol44 59 11 2412.3IL10, LTA, TNF
40vitamin d449.3GPT, IL10, LTA
41atorvastatin44 49 28 11 2413.3GPT, IL10, TNF
42simvastatin44 49 59 28 11 2414.3TNF, IL10, GPT
43rantes449.3IL10, LTA, TNF
44tacrolimus44 49 1111.3GPT, IL10, TNF
45methotrexate44 49 1111.2TNF, IL10, GPT
46lactate449.2GPT, LTA, TNF
47ccl344 2810.0IL10, TNF
48neopterin448.9GPT, IL10, LTA, TNF
49cyclosporin a44 28 5910.9TNF, LTA, IL10, GPT

GO Terms for genes affiliated with Coronary Aneurysm

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16Gene Ontology
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Biological processes related to Coronary Aneurysm according to GeneCards/GeneDecks:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chronic inflammatory response to antigenic stimulusGO:0028769.8LTA, TNF
2positive regulation of humoral immune response mediated by circulating immunoglobulinGO:0029259.7LTA, TNF
3receptor biosynthetic processGO:0328009.6IL10, TNF
4negative regulation of cytokine secretion involved in immune responseGO:0027409.6TNF, IL10
5positive regulation of interferon-gamma productionGO:0327299.5TNF, LTA
6negative regulation of interleukin-6 productionGO:0327159.5IL10, TNF
7response to activityGO:0148239.5TNF, IL10
8defense response to Gram-positive bacteriumGO:0508309.4LTA, TNF
9positive regulation of cytokine secretionGO:0507159.4IL10, TNF
10response to glucocorticoid stimulusGO:0513849.3IL10, TNF
11humoral immune responseGO:0069599.2LTA, TNF
12negative regulation of growth of symbiont in hostGO:0441309.2IL10, LTA, TNF
13response to drugGO:0424939.0IL10, LTA, TNF

Molecular functions related to Coronary Aneurysm according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:0051649.5LTA, TNF
2cytokine activityGO:0051258.6IL10, LTA, TNF

Products for genes affiliated with Coronary Aneurysm

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  • Antibodies
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  • Antibodies

Sources for Coronary Aneurysm

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet