MCID: CRN006
MIFTS: 47

Coronary Aneurysm malady

Summaries for Coronary Aneurysm

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63Wikipedia, 32MalaCards
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Wikipedia:63 Coronary artery aneurysm is an abnormal dilatation of part of the coronary artery. more...

MalaCards: Coronary Aneurysm, also known as arteriovenous aneurysm of coronary vessels, is related to kawasaki disease and myocardial infarction. An important gene associated with Coronary Aneurysm is LTA (lymphotoxin alpha), and among its related pathways are RIP-mediated NFkB activation via ZBP1 and Transcription NF-kB signaling pathway. The compounds prednisolone and pentoxifylline have been mentioned in the context of this disorder. Affiliated tissues include heart, lymph node and kidney, and related mouse phenotype respiratory system.

Aliases & Classifications for Coronary Aneurysm

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH, 27ICD9CM
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Aliases & Descriptions:

coronary aneurysm 8 10 60
arteriovenous aneurysm of coronary vessels 8
aneurysmal lesion of coronary artery 8
aneurysm of coronary vessels 8


External Ids:

Disease Ontology8 DOID:3362
MeSH34 D003323
SNOMED-CT56 373139003, 50570003
ICD9CM27 414.11

Related Diseases for Coronary Aneurysm

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Coronary Aneurysm:



Diseases related to coronary aneurysm

Clinical Features for Coronary Aneurysm

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Drugs & Therapeutics for Coronary Aneurysm

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Coronary Aneurysm

Drug clinical trials:

Search ClinicalTrials for Coronary Aneurysm

Search NIH Clinical Center for Coronary Aneurysm

Search CenterWatch for Coronary Aneurysm

Genetic Tests for Coronary Aneurysm

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Anatomical Context for Coronary Aneurysm

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32MalaCards
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MalaCards organs/tissues related to Coronary Aneurysm:

32
Heart, Lymph node, Kidney, T cells, Endothelial, Lung, Prostate, Trachea

Animal Models for Coronary Aneurysm or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Coronary Aneurysm:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.4LDB3, IL10, LTA, TNF

Publications for Coronary Aneurysm

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50PubMed
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Articles related to Coronary Aneurysm:

(show top 50)    (show all 756)
idTitleAuthorsYear
1
Staged Hybrid Treatment for Contained Rupture of a Large Right Coronary Artery Aneurysm. (24406321)
2014
2
Excising a giant: report of a 7-cm coronary artery aneurysm. (23678216)
2013
3
Giant coronary artery aneurysm seen on blood-pool study. (23242065)
2013
4
A giant coronary artery aneurysm with coronary arteriovenous fistula in asymptomatic elderly patient. (24324914)
2013
5
The Diagnosis and Treatment of a Mycotic Coronary Artery Aneurysm: A Case Report. (23937587)
2013
6
Giant left main coronary artery aneurysm in a cocaine abuser. (23070202)
2013
7
Coronary artery aneurysm after implantation of an endothelial progenitor cell capturing stent. (22718389)
2012
8
Rapidly progressing coronary artery aneurysm and left ventricular diverticulum. (22870753)
2012
9
Coil embolization for distal left main aneurysm: a new approach to coronary artery aneurysm treatment. (21735516)
2012
10
Serum levels of IgG4 and soluble interleukin-2 receptor in patients with abdominal and thoracic aortic aneurysm who undergo coronary angiography. (22377395)
2012
11
Sinus of Valsalva aneurysm with left anterior descending coronary aneurysm. (22978839)
2012
12
A giant coronary aneurysm associated with a fractured cobalt-chromium stent. (22611141)
2012
13
Successful transcatheter patent ductus arteriosus occluder embolization of a congenital left coronary artery aneurysm and fistulas draining into the right atrium. (22673605)
2012
14
Rapidly evolving coronary aneurysm in a patient with rheumatoid arthritis. (21403892)
2011
15
Coronary aneurysm and factor V Leiden mutation: A coincidence or an association? (21501985)
2011
16
Case images: progression of coronary artery aneurysms in incomplete Kawasaki disease. (21358238)
2011
17
Left main coronary artery aneurysm. (21425744)
2011
18
Congenital left main coronary artery aneurysm. (21769824)
2011
19
Sudden cardiac death resulting from acute coronary artery aneurysm occlusion: successful resuscitation and treatment of an adolescent boy with previously unrecognized Kawasaki disease. (21441798)
2011
20
RETRACTED: Successful correction of congenital giant right coronary artery aneurysm with fistula to left ventricle: [Interact CardioVasc Thorac Surg 2011;12(4):639-641]. (21659324)
2011
21
Comparison study of echocardiography and dual-source CT in diagnosis of coronary artery aneurysm due to Kawasaki disease: coronary artery disease. (21854436)
2011
22
Kawasaki disease presenting as cardiac tamponade with ruptured giant aneurysm of the right coronary artery. (19910362)
2010
23
Giant coronary aneurysm in a patient with systemic lupus erythematosus. (19687588)
2009
24
Early stent thrombosis because of stent dislodgement in a coronary artery aneurysm. (19145039)
2009
25
A fractured sirolimus-eluting stent with a coronary aneurysm. (19632438)
2009
26
Surgical treatment of left main coronary artery aneurysm: a case report. (19075521)
2009
27
Right coronary artery aneurysm: possible relation with obesity? (17655956)
2008
28
Drug-eluting stent-induced left anterior descending coronary artery aneurysm: repair by pericardial patch--where are we headed? (17383377)
2007
29
Huge right coronary artery aneurysm in a young adult. (16956915)
2006
30
Images in cardiology: giant coronary aneurysm in the septal branch. (16287752)
2005
31
Images in cardiovascular medicine. Giant coronary aneurysm formation after sirolimus-eluting stent implantation in Kawasaki disease. (16116061)
2005
32
Usefulness of transthoracic echocardiography to detect coronary aneurysm in young adult: two cases of acute myocardial infarction due to Kawasaki disease. (14961797)
2004
33
Use of intravascular ultrasound in evaluating coronary artery aneurysm. (12381633)
2002
34
Sudden infant death caused by a ruptured coronary aneurysm during acute phase of atypical Kawasaki disease. (11774178)
2001
35
Imaging a coronary artery aneurysm. (11789823)
2001
36
Left main coronary artery aneurysm: sealing by stent graft and long-term follow-up. (11025578)
2000
37
Myocardial infarction caused by a large coronary artery aneurysm. (10881843)
2000
38
Coronary aneurysm after endovascular brachytherapy: true or false? (11056112)
2000
39
Surgical treatment of a coronary artery fistula with concomitant saccular coronary artery aneurysm: a case report. (10553926)
1999
40
Surgical management of arteriosclerotic coronary artery aneurysm. (10532212)
1999
41
Autologous vein-coated stent for exclusion of a coronary artery aneurysm: case report with postimplantation intravascular ultrasound characteristics. (10524747)
1999
42
A huge coronary aneurysm resulting from a coronary artery-to-left ventricle fistula. (9630195)
1998
43
Anticoagulant therapy during successful pregnancy and delivery in a Kawasaki disease patient with coronary aneurysm--a case report. (9070977)
1997
44
Plaque rupture as a cause of apparent coronary aneurysm formation following directional coronary atherectomy. (9143766)
1997
45
Coronary artery aneurysm associated with adult supravalvular aortic stenosis. (8823123)
1996
46
Giant coronary artery aneurysm: detection with echocardiography, computed tomography, and magnetic resonance imaging. (2017988)
1991
47
Coronary artery aneurysm without stenosis in association with Osler-Weber-Rendu disease--a case report. (1992858)
1991
48
Surgical treatment of an isolated coronary artery aneurysm: an alternative approach. (1992256)
1991
49
Large multiple coronary artery aneurysm in adult patients: a report on three patients and a review of the literature. (6103670)
1980
50
Rupture of chronic left ventricular aneurysm after acute coronary thrombosis. (5073667)
1972

Genetic Variations for Coronary Aneurysm

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Expression for genes affiliated with Coronary Aneurysm

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Coronary Aneurysm

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Pathways for genes affiliated with Coronary Aneurysm

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53Reactome, 51QIAGEN, 12EMD Millipore, 37NCBI BioSystems Database, 29KEGG, 52R&D Systems
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Compounds for genes affiliated with Coronary Aneurysm

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Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 49PharmGKB, 59Tocris Bioscience, 24HMDB
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Compounds related to Coronary Aneurysm according to GeneCards/GeneDecks:

(show all 49)
idCompoundScoreTop Affiliating Genes
1prednisolone44 28 1112.5LTA
2pentoxifylline44 1111.5LTA
3ivig4410.5GPT
4d-galactosamine449.9TNF, GPT
5nash449.9GPT, TNF
6cdp571449.7IL10, TNF
7interferon gamma449.7TNF, IL10
86 mercaptopurine449.7IL10, GPT
9blys449.7IL10, TNF
10mip 1alpha449.7TNF, IL10
11natalizumab44 1110.7IL10, TNF
12adalimumab44 49 1111.7TNF, IL10
135 aminosalicylic acid449.7IL10, TNF
14il-12449.7IL10, TNF
15fenofibrate44 49 1111.6TNF, GPT
16imiquimod44 28 59 1112.6TNF, IL10
17polymyxin b449.6IL10, TNF
18risperidone28 44 49 59 11 2414.6GPT, IL10
19groalpha449.6TNF, IL10
20gm-csf44 2810.6IL10, TNF
21mycophenolate mofetil44 49 1111.6GPT, IL10
228-isoprostane449.6IL10, TNF
23polyinosinic-polycytidylic acid449.6TNF, IL10
24tarc449.5TNF, IL10
25carbamazepine44 49 1111.4LTA, TNF
26ribavirin44 49 1111.4IL10, GPT
27peptidoglycan44 2810.4IL10, TNF
28ifn-alpha449.4GPT, IL10
29thyroxine44 2410.4GPT, IL10, LTA
30toxin-1449.4IL10, LTA, TNF
31okt3449.4IL10, LTA, TNF
32lipoteichoic acid449.4IL10, LTA, TNF
33etanercept44 49 1111.4IL10, LTA, TNF
34il 10449.4TNF, LTA, IL10
35infliximab44 49 1111.3IL10, LTA, TNF
36tgf beta1449.3IL10, LTA, TNF
372,5-oligoadenylate449.3TNF, IL10, GPT
38ionomycin449.3TNF, LTA, IL10
39calcitriol44 59 11 2412.3IL10, LTA, TNF
40vitamin d449.3GPT, IL10, LTA
41atorvastatin44 49 28 11 2413.3GPT, IL10, TNF
42simvastatin44 49 59 28 11 2414.3TNF, IL10, GPT
43rantes449.3IL10, LTA, TNF
44tacrolimus44 49 1111.3GPT, IL10, TNF
45methotrexate44 49 1111.2TNF, IL10, GPT
46lactate449.2GPT, LTA, TNF
47ccl344 2810.0IL10, TNF
48neopterin448.9GPT, IL10, LTA, TNF
49cyclosporin a44 28 5910.9TNF, LTA, IL10, GPT

GO Terms for genes affiliated with Coronary Aneurysm

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16Gene Ontology
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Biological processes related to Coronary Aneurysm according to GeneCards/GeneDecks:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chronic inflammatory response to antigenic stimulusGO:0028769.8LTA, TNF
2positive regulation of humoral immune response mediated by circulating immunoglobulinGO:0029259.7LTA, TNF
3receptor biosynthetic processGO:0328009.6IL10, TNF
4negative regulation of cytokine secretion involved in immune responseGO:0027409.6TNF, IL10
5positive regulation of interferon-gamma productionGO:0327299.5TNF, LTA
6negative regulation of interleukin-6 productionGO:0327159.5IL10, TNF
7response to activityGO:0148239.5TNF, IL10
8defense response to Gram-positive bacteriumGO:0508309.4LTA, TNF
9positive regulation of cytokine secretionGO:0507159.4IL10, TNF
10response to glucocorticoid stimulusGO:0513849.3IL10, TNF
11humoral immune responseGO:0069599.2LTA, TNF
12negative regulation of growth of symbiont in hostGO:0441309.2IL10, LTA, TNF
13response to drugGO:0424939.0IL10, LTA, TNF

Molecular functions related to Coronary Aneurysm according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:0051649.5LTA, TNF
2cytokine activityGO:0051258.6IL10, LTA, TNF

Products for genes affiliated with Coronary Aneurysm

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  • Antibodies
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  • Antibodies

Sources for Coronary Aneurysm

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet