MCID: CRN006
MIFTS: 40

Coronary Aneurysm malady

Summaries for Coronary Aneurysm

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MalaCards based summary: Coronary Aneurysm, also known as arteriovenous aneurysm of coronary vessels, is related to systemic lupus erythematosus and pneumonia. An important gene associated with Coronary Aneurysm is LDB3 (LIM domain binding 3), and among its related pathways are TRAF Pathway and Cellular Transformation by HTLV1. The compounds rantes and d-galactosamine have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and endothelial, and related mouse phenotypes are limbs/digits/tail and liver/biliary system.

Aliases & Classifications for Coronary Aneurysm

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Coronary Aneurysm, Aliases & Descriptions:

Name: Coronary Aneurysm 9 11 60
Arteriovenous Aneurysm of Coronary Vessels 9
 
Aneurysmal Lesion of Coronary Artery 9
Aneurysm of Coronary Vessels 9


External Ids:

Disease Ontology9 DOID:3362
ICD9CM27 414.11
SNOMED-CT55 373139003, 50570003
MeSH33 D003323

Related Diseases for Coronary Aneurysm

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Diseases related to Coronary Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 84)
idRelated DiseaseScoreTop Affiliating Genes
1systemic lupus erythematosus30.2LTA, IL10, TNF
2pneumonia29.8IL10, TNF
3arthritis29.8LTA, IL10, TNF
4rheumatoid arthritis29.7TNF, IL10, LTA
5aneurysm11.2
6kawasaki disease10.9
7myocardial infarction10.7
8acute myocardial infarction10.6
9blau syndrome10.4TNF
10psoriatic arthritis10.4TNF
11polyarteritis nodosa10.3
12lupus erythematosus10.3
13leishmaniasis10.3IL10
14arteriovenous fistula10.2
15neurofibromatosis10.2
16polycystic kidney disease10.2
17churg-strauss syndrome10.2
18atrial fibrillation10.2
19kidney disease10.2
20hypereosinophilic syndrome10.2
21toxic shock syndrome10.2TNF, LTA
22pulmonary sarcoidosis10.2LTA, TNF
23juvenile rheumatoid arthritis10.2TNF, LTA
24acute respiratory distress syndrome10.2TNF, LTA
25behcet's disease10.2TNF, LTA
26alcoholic hepatitis10.1GPT, TNF
27sarcoidosis 110.1LTA, TNF
28hypertriglyceridemia10.1GPT, LTA
29primary biliary cirrhosis10.1LTA, GPT
30liver disease10.1TNF, IL10
31selective iga deficiency disease10.1LTA, IL10
32lepromatous leprosy10.1IL10, LTA
33visceral leishmaniasis10.1IL10, LTA
34malaria10.0TNF, IL10
35demyelinating disease10.0TNF, IL10
36coronary artery disease10.0LTA, LDB3
37pregnancy loss, recurrent 110.0IL10, LTA
38marfan syndrome10.0
39neurofibromatosis, type 110.0
40melioidosis10.0
41takayasu's arteritis10.0
42cardiac tamponade10.0
43lyme disease10.0
44coronary thrombosis10.0
45hemopericardium10.0
46silent myocardial infarction10.0
47intracranial aneurysm10.0
48mediastinitis10.0
49pericardial effusion10.0
50pericarditis10.0

Graphical network of the top 20 diseases related to Coronary Aneurysm:



Diseases related to coronary aneurysm

Symptoms for Coronary Aneurysm

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Drugs & Therapeutics for Coronary Aneurysm

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Drug clinical trials:

Search ClinicalTrials for Coronary Aneurysm

Search NIH Clinical Center for Coronary Aneurysm

Genetic Tests for Coronary Aneurysm

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Anatomical Context for Coronary Aneurysm

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MalaCards organs/tissues related to Coronary Aneurysm:

31
Heart, Kidney, Endothelial, Neutrophil

Animal Models for Coronary Aneurysm or affiliated genes

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MGI Mouse Phenotypes related to Coronary Aneurysm:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.6LTA, IL10, TNF
2MP:00053708.3LTA, IL10, TNF
3MP:00053888.3LTA, IL10, LDB3, TNF
4MP:00053858.2TNF, LDB3, IL10, LTA
5MP:00053788.2LTA, IL10, LDB3, TNF
6MP:00053868.1TNF, LDB3, IL10, LTA

Publications for Coronary Aneurysm

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Articles related to Coronary Aneurysm:

(show top 50)    (show all 240)
idTitleAuthorsYear
1
Massive coronary aneurysm after multiple percutaneous interventions: an iatrogenic or unpreventable disaster? (24456720)
2014
2
Coronary aneurysm after paclitaxel-eluting balloon angioplasty. (25443816)
2014
3
Acute coronary thrombosis and multiple coronary aneurysms in a 22-year-old man with the human immunodeficiency virus. (24808786)
2014
4
Coronary Aneurysm After Paclitaxel-eluting Balloon Angioplasty. (24841291)
2014
5
A Case of Kawasaki Disease with Coronary Aneurysm Responding to the 4th IVIG Treatment. (25161773)
2014
6
Bilateral giant coronary aneurysms in Kawasaki disease: how difficult can it be? (24218442)
2013
7
Bentall procedure for an adult patient with supravalvular aortic stenosis and coronary aneurysms. (23879341)
2013
8
Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction in a Pediatric Patient with Giant Coronary Aneurysm Due to Kawasaki Disease. (23601472)
2013
9
Coronary Artery Bypass Grafting in a Patient with Polyarteritis Nodosa Presenting with Acute Myocardial Infarction and Multiple Coronary Aneurysms. (23995351)
2013
10
National Japanese survey of thrombolytic therapy selection for coronary aneurysm: Intracoronary thrombolysis or intravenous coronary thrombolysis in patients with Kawasaki disease. (23919576)
2013
11
Intracoronary thrombus in an infant with Kawasaki disease and giant coronary aneurysm. (23368954)
2013
12
Rare insight into the rapid evolution of a coronary aneurysm and fistula. (24076292)
2013
13
Reversible stenosis of the saphenous vein graft compressed by giant coronary aneurysm in Kawasaki disease. (23660427)
2013
14
Coronary aneurysm formation following biodegradable polymer drug-eluting stent implantation. (22257689)
2012
15
Rapidly evolving coronary aneurysm in a patient with rheumatoid arthritis. (21403892)
2011
16
Myocardial infarction in a youngster due to giant coronary aneurysm. (21351229)
2011
17
Coronary aneurysm with double right coronary artery and fistula. (21241866)
2011
18
Very late coronary aneurysm formation with subsequent stent thrombosis secondary to drug-eluting stent. (22088549)
2011
19
Case images: giant coronary aneurysm accompanied by a coronary artery fistula. (20935441)
2010
20
Impressive combination of multiple sinus valsalvae and coronary aneurysms due to hypereosinophilic syndrome. (20971227)
2010
21
Natural history of a giant coronary aneurysm with spontaneous dissection. (20014206)
2009
22
Giant coronary aneurysm in a patient with systemic lupus erythematosus. (19687588)
2009
23
Left anterior descending coronary aneurysm. (19515889)
2009
24
Cardiovascular images. Giant right coronary aneurysm to left ventricular fistula. (19808583)
2009
25
Case report: Giant coronary aneurysm caused by Kawasaki disease: follow-up with echocardiography and multidetector CT angiography. (18344266)
2008
26
Coronary aneurysm in Lyme Disease: treatment by covered stent. (17692941)
2008
27
Coronary aneurysm formation in a patient early after everolimus-eluting stent implantation. (18460723)
2008
28
Rapid development of late stent malappositon and coronary aneurysm following implantation of a paclitaxel-eluting coronary stent. (17442215)
2007
29
Late stent thrombosis associated with coronary aneurysm formation after sirolimus-eluting stent implantation. (17404416)
2007
30
Development of coronary aneurysm after drug-eluting stent implantation. (17283357)
2007
31
Giant coronary aneurysm following drug-eluting stent implantation presenting as fever of unknown origin. (17620677)
2007
32
Noninvasive evaluation of left circumflex coronary aneurysm by real-time three-dimensional echocardiography. (15908280)
2006
33
Images in cardiology: giant coronary aneurysm in the septal branch. (16287752)
2005
34
Polytetrafluoroethylene stent deployment for a left anterior descending coronary aneurysm complicated by late acute anterior myocardial infarction. (16061748)
2005
35
Percutaneous treatment of a large coronary aneurysm using the self-expandable Symbiot PTFE-covered stent. (15302758)
2004
36
Elevated levels of matrix metalloprotein-3 in patients with coronary aneurysm: A case control study. (15482602)
2004
37
Stent implantation for coronary aneurysm with edge stenosis: angiographic and intravascular analysis. (15152166)
2004
38
Treatment of coronary aneurysm in acute myocardial infarction with AngioJet thrombectomy and JoStent coronary stent graft. (15152122)
2004
39
Surgical treatment of annuloaortic ectasia with coronary aneurysm and fistula. (11426789)
2001
40
Large atherosclerotic left main coronary aneurysm--a case report and review of the literature. (11515991)
2001
41
Intraseptal coronary aneurysm. (10969706)
2000
42
Transthoracic ultrasonic visualisation of coronary aneurysm, stenosis, and occlusion in Kawasaki disease. (10722537)
2000
43
Morphologic and functional assessment of coronary aneurysm after Kawasaki disease by repeated dipyridamole-loading coronary angiography. (9708673)
1998
44
Recurrent myocardial infarction caused by a giant coronary aneurysm. (9578359)
1998
45
Coronary aneurysm after bailout stent implantation: diagnosis of a false lumen with intravascular ultrasound. (9258484)
1997
46
Anticoagulant therapy during successful pregnancy and delivery in a Kawasaki disease patient with coronary aneurysm--a case report. (9070977)
1997
47
Development of a coronary aneurysm 6 months after stent implantation assessed by intracoronary ultrasound. (8721665)
1996
48
Long-term prognosis of giant coronary aneurysm in Kawasaki disease: an angiographic study. (3668739)
1987
49
Coronary aneurysm: isolated necrotizing angitis of a major coronary artery. Report of a case. (4149915)
1974
50
Coronary aneurysm with arteriovenous fistula. (13180479)
1954

Variations for Coronary Aneurysm

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Expression for genes affiliated with Coronary Aneurysm

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Search GEO for disease gene expression data for Coronary Aneurysm.

Pathways for genes affiliated with Coronary Aneurysm

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Pathways related to Coronary Aneurysm according to GeneCards Suite gene sharing:

(show all 30)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.4TNF, LTA
2
Show member pathways
9.4LTA, TNF
3
Show member pathways
9.4LTA, TNF
4
Show member pathways
Apoptosis Modulation and Signaling36
Apoptosis36
9.4LTA, TNF
59.4LTA, TNF
6
Show member pathways
Transcription NF kB signaling pathway58
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response58
9.4LTA, TNF
7
Show member pathways
9.4LTA, TNF
8
Show member pathways
Apoptosis and survival TNFR1 signaling pathway58
TWEAK Signaling Pathway36
Apoptosis Modulation by HSP7036
HIV-1 Nef- Negative effector of Fas and TNF-alpha36
9.4LTA, TNF
9
Show member pathways
IL-9 Signaling Pathway36
Development Thrombopoietin regulated cell processes58
IL-7 Signaling Pathway36
Immune response IL 9 signaling pathway58
9.4TNF, LTA
10
Show member pathways
9.4LTA, TNF
119.4LTA, TNF
129.1LTA, IL10
139.1LTA, IL10
149.1TNF, IL10
15
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
9.1IL10, TNF
169.1IL10, TNF
179.1TNF, IL10
189.1TNF, IL10
19
Show member pathways
9.1IL10, TNF
209.1IL10, TNF
219.1IL10, TNF
229.1TNF, IL10
23
Show member pathways
8.6TNF, IL10, LTA
24
Show member pathways
IL27-mediated signaling events36
8.6LTA, IL10, TNF
25
Show member pathways
8.6LTA, IL10, TNF
268.6LTA, IL10, TNF
27
Show member pathways
8.6LTA, IL10, TNF
28
Show member pathways
8.6LTA, IL10, TNF
29
Show member pathways
8.6LTA, IL10, TNF
30
Show member pathways
8.6TNF, IL10, LTA

Compounds for genes affiliated with Coronary Aneurysm

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Compounds related to Coronary Aneurysm according to GeneCards Suite gene sharing:

(show top 50)    (show all 76)
idCompoundScoreTop Affiliating Genes
1rantes4310.0IL10
2d-galactosamine439.7TNF, GPT
3nash439.7GPT, TNF
4cdp571439.5IL10, TNF
5interferon gamma439.5IL10, TNF
6blys439.5IL10, TNF
7gabexate mesilate439.5IL10, TNF
8ulinastatin439.5IL10, TNF
9mip 1alpha439.5IL10, TNF
10natalizumab43 1210.5IL10, TNF
115 aminosalicylic acid439.4TNF, IL10
12il-12439.4TNF, IL10
13adalimumab43 49 1211.4IL10, TNF
14indoleamine439.4IL10, TNF
15imiquimod43 59 28 1212.4TNF, IL10
16polymyxin b439.4IL10, TNF
176 mercaptopurine439.3IL10, GPT
18groalpha439.3IL10, TNF
19gm-csf43 2810.3TNF, IL10
208-isoprostane439.2IL10, TNF
21lamivudine43 49 1211.2IL10, GPT
22toxin-1439.1TNF, IL10, LTA
23cyclosporine49 1210.1LTA, IL10, TNF
24okt3439.0LTA, IL10, TNF
25lipoteichoic acid439.0TNF, IL10, LTA
26etanercept43 49 1211.0TNF, IL10, LTA
27il 10439.0LTA, IL10, TNF
28infliximab43 49 1211.0LTA, IL10, TNF
29polyinosinic-polycytidylic acid439.0IL10, TNF
30risperidone43 49 28 59 24 1214.0IL10, GPT
31pentoxifylline43 1210.0TNF, IL10, LTA
32tgf beta1439.0TNF, IL10, LTA
33endotoxin439.0TNF, IL10, LTA
34ionomycin439.0LTA, IL10, TNF
35calcitriol43 59 24 1212.0TNF, IL10, LTA
362,5-oligoadenylate438.9IL10, TNF, GPT
37atorvastatin43 49 28 24 1212.9GPT, TNF, IL10
38simvastatin43 49 59 28 24 1213.9IL10, TNF, GPT
39thyroxine43 249.9LTA, IL10, GPT
40tacrolimus43 49 1210.9IL10, TNF, GPT
41methotrexate49 43 1210.9GPT, TNF, IL10
42rolipram43 59 2810.8IL10, TNF
43vitamin d438.8LTA, IL10, GPT
44lactate438.8GPT, TNF, LTA
45pge2438.7LTA, IL10, TNF
46mycophenolate mofetil43 49 1210.4LTA, IL10, TNF, GPT
47ivig438.4GPT, TNF, IL10, LTA
48neopterin438.4GPT, TNF, IL10, LTA
49prednisolone43 28 1210.4LTA, IL10, TNF, GPT
50cyclosporin a43 28 5910.4LTA, IL10, TNF, GPT

GO Terms for genes affiliated with Coronary Aneurysm

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Cellular components related to Coronary Aneurysm according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.6LTA, IL10, TNF

Biological processes related to Coronary Aneurysm according to GeneCards Suite gene sharing:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chronic inflammatory response to antigenic stimulusGO:00028769.7LTA, TNF
2positive regulation of humoral immune response mediated by circulating immunoglobulinGO:00029259.7LTA, TNF
3cellular amino acid biosynthetic processGO:00086529.6TNF, GPT
4defense response to Gram-positive bacteriumGO:00508309.5LTA, TNF
5positive regulation of interferon-gamma productionGO:00327299.5TNF, LTA
6humoral immune responseGO:00069599.4LTA, TNF
7response to hypoxiaGO:00016669.4LTA, TNF
8receptor biosynthetic processGO:00328009.4IL10, TNF
9negative regulation of cytokine secretion involved in immune responseGO:00027409.4TNF, IL10
10negative regulation of interleukin-6 productionGO:00327159.4IL10, TNF
11positive regulation of cytokine secretionGO:00507159.3IL10, TNF
12response to activityGO:00148239.3IL10, TNF
13response to glucocorticoidGO:00513849.0IL10, TNF
14negative regulation of growth of symbiont in hostGO:00441308.9LTA, IL10, TNF
15positive regulation of sequence-specific DNA binding transcription factor activityGO:00510918.8IL10, TNF
16response to drugGO:00424938.8TNF, IL10, LTA

Molecular functions related to Coronary Aneurysm according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:00051649.4LTA, TNF
2cytokine activityGO:00051258.3LTA, IL10, TNF

Products for genes affiliated with Coronary Aneurysm

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Sources for Coronary Aneurysm

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet