MCID: CRN006
MIFTS: 49

Coronary Aneurysm malady

Cardiovascular diseases category
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Summaries for Coronary Aneurysm

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Wikipedia:65 Coronary artery aneurysm is an abnormal dilatation of part of the coronary artery. more...

MalaCards based summary: Coronary Aneurysm, also known as arteriovenous aneurysm of coronary vessels, is related to systemic lupus erythematosus and pneumonia. An important gene associated with Coronary Aneurysm is LDB3 (LIM domain binding 3), and among its related pathways are TRAF Pathway and Cellular Transformation by HTLV1. The compounds rantes and d-galactosamine have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and lymph node, and related mouse phenotypes are limbs/digits/tail and liver/biliary system.

Aliases & Classifications for Coronary Aneurysm

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Coronary Aneurysm, Aliases & Descriptions:

Name: Coronary Aneurysm 8 10 62
Arteriovenous Aneurysm of Coronary Vessels 8 62
 
Aneurysmal Lesion of Coronary Artery 8 62
Aneurysm of Coronary Vessels 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


External Ids:

Disease Ontology8 DOID:3362
MeSH34 D003323
SNOMED-CT57 373139003, 50570003
ICD9CM27 414.11

Related Diseases for Coronary Aneurysm

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Diseases related to Coronary Aneurysm via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 83)
idRelated DiseaseScoreTop Affiliating Genes
1systemic lupus erythematosus30.2IL10, LTA, TNF
2pneumonia29.9IL10, TNF
3arthritis29.8LTA, IL10, TNF
4rheumatoid arthritis29.7TNF, LTA, IL10
5aneurysm11.2
6kawasaki disease10.9
7myocardial infarction10.7
8acute myocardial infarction10.6
9blau syndrome10.4TNF
10psoriatic arthritis10.4TNF
11polyarteritis nodosa10.3
12lupus erythematosus10.3
13leishmaniasis10.3IL10
14toxic shock syndrome10.2LTA, TNF
15arteriovenous fistula10.2
16polycystic kidney disease10.2
17churg-strauss syndrome10.2
18kidney disease10.2
19hypereosinophilic syndrome10.2
20pulmonary sarcoidosis10.2LTA, TNF
21juvenile rheumatoid arthritis10.2LTA, TNF
22adult respiratory distress syndrome10.2TNF, LTA
23behcet's disease10.2TNF, LTA
24alcoholic hepatitis10.1GPT, TNF
25sarcoidosis10.1TNF, LTA
26hypertriglyceridemia10.1GPT, LTA
27primary biliary cirrhosis10.1LTA, GPT
28galactosemia10.1TNF, IL10
29selective iga deficiency disease10.1IL10, LTA
30lepromatous leprosy10.1LTA, IL10
31visceral leishmaniasis10.1IL10, LTA
32cerebral malaria10.1TNF, IL10
33demyelinating disease10.0TNF, IL10
34coronary artery anomaly10.0LTA, LDB3
35familial hypercholesterolemia10.0
36takayasu's arteritis10.0
37marfan syndrome10.0
38cardiac tamponade10.0
39supravalvular aortic stenosis10.0
40silent myocardial infarction10.0
41lyme disease10.0
42coronary thrombosis10.0
43neurofibromatosis10.0
44intracranial aneurysm10.0
45hemopericardium10.0
46pericardial effusion10.0
47pericarditis10.0
48aortic coarctation10.0
49chronic active epstein-barr virus infection10.0
50fibromuscular dysplasia10.0

Graphical network of the top 20 diseases related to Coronary Aneurysm:



Diseases related to coronary aneurysm

Symptoms for Coronary Aneurysm

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Drugs & Therapeutics for Coronary Aneurysm

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Drug clinical trials:

Search ClinicalTrials for Coronary Aneurysm

Search NIH Clinical Center for Coronary Aneurysm

Genetic Tests for Coronary Aneurysm

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Anatomical Context for Coronary Aneurysm

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MalaCards organs/tissues related to Coronary Aneurysm:

32
Heart, Kidney, Lymph node, Endothelial, Neutrophil

Animal Models for Coronary Aneurysm or affiliated genes

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MGI Mouse Phenotypes related to Coronary Aneurysm:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.6IL10, LTA, TNF
2MP:00053708.3LTA, IL10, TNF
3MP:00053888.3TNF, LDB3, IL10, LTA
4MP:00053858.2LTA, IL10, LDB3, TNF
5MP:00053788.2LTA, TNF, LDB3, IL10
6MP:00053868.1LTA, LDB3, TNF, IL10

Publications for Coronary Aneurysm

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Articles related to Coronary Aneurysm:

(show top 50)    (show all 234)
idTitleAuthorsYear
1
Massive coronary aneurysm after multiple percutaneous interventions: an iatrogenic or unpreventable disaster? (24456720)
2014
2
Acute coronary thrombosis and multiple coronary aneurysms in a 22-year-old man with the human immunodeficiency virus. (24808786)
2014
3
Coronary Aneurysm After Paclitaxel-eluting Balloon Angioplasty. (24841291)
2014
4
A Case of Kawasaki Disease with Coronary Aneurysm Responding to the 4th IVIG Treatment. (25161773)
2014
5
Bilateral giant coronary aneurysms in Kawasaki disease: how difficult can it be? (24218442)
2013
6
Bentall procedure for an adult patient with supravalvular aortic stenosis and coronary aneurysms. (23879341)
2013
7
Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction in a Pediatric Patient with Giant Coronary Aneurysm Due to Kawasaki Disease. (23601472)
2013
8
Coronary Artery Bypass Grafting in a Patient with Polyarteritis Nodosa Presenting with Acute Myocardial Infarction and Multiple Coronary Aneurysms. (23995351)
2013
9
National Japanese survey of thrombolytic therapy selection for coronary aneurysm: Intracoronary thrombolysis or intravenous coronary thrombolysis in patients with Kawasaki disease. (23919576)
2013
10
Intracoronary thrombus in an infant with Kawasaki disease and giant coronary aneurysm. (23368954)
2013
11
Rare insight into the rapid evolution of a coronary aneurysm and fistula. (24076292)
2013
12
Reversible stenosis of the saphenous vein graft compressed by giant coronary aneurysm in Kawasaki disease. (23660427)
2013
13
Coronary aneurysm formation following biodegradable polymer drug-eluting stent implantation. (22257689)
2012
14
Rapidly evolving coronary aneurysm in a patient with rheumatoid arthritis. (21403892)
2011
15
Myocardial infarction in a youngster due to giant coronary aneurysm. (21351229)
2011
16
Coronary aneurysm with double right coronary artery and fistula. (21241866)
2011
17
Very late coronary aneurysm formation with subsequent stent thrombosis secondary to drug-eluting stent. (22088549)
2011
18
Case images: giant coronary aneurysm accompanied by a coronary artery fistula. (20935441)
2010
19
Impressive combination of multiple sinus valsalvae and coronary aneurysms due to hypereosinophilic syndrome. (20971227)
2010
20
Natural history of a giant coronary aneurysm with spontaneous dissection. (20014206)
2009
21
Giant coronary aneurysm in a patient with systemic lupus erythematosus. (19687588)
2009
22
Left anterior descending coronary aneurysm. (19515889)
2009
23
Cardiovascular images. Giant right coronary aneurysm to left ventricular fistula. (19808583)
2009
24
Case report: Giant coronary aneurysm caused by Kawasaki disease: follow-up with echocardiography and multidetector CT angiography. (18344266)
2008
25
Coronary aneurysm in Lyme Disease: treatment by covered stent. (17692941)
2008
26
Coronary aneurysm formation in a patient early after everolimus-eluting stent implantation. (18460723)
2008
27
Rapid development of late stent malappositon and coronary aneurysm following implantation of a paclitaxel-eluting coronary stent. (17442215)
2007
28
Late stent thrombosis associated with coronary aneurysm formation after sirolimus-eluting stent implantation. (17404416)
2007
29
Development of coronary aneurysm after drug-eluting stent implantation. (17283357)
2007
30
Giant coronary aneurysm following drug-eluting stent implantation presenting as fever of unknown origin. (17620677)
2007
31
Noninvasive evaluation of left circumflex coronary aneurysm by real-time three-dimensional echocardiography. (15908280)
2006
32
Images in cardiology: giant coronary aneurysm in the septal branch. (16287752)
2005
33
Polytetrafluoroethylene stent deployment for a left anterior descending coronary aneurysm complicated by late acute anterior myocardial infarction. (16061748)
2005
34
Percutaneous treatment of a large coronary aneurysm using the self-expandable Symbiot PTFE-covered stent. (15302758)
2004
35
Elevated levels of matrix metalloprotein-3 in patients with coronary aneurysm: A case control study. (15482602)
2004
36
Stent implantation for coronary aneurysm with edge stenosis: angiographic and intravascular analysis. (15152166)
2004
37
Treatment of coronary aneurysm in acute myocardial infarction with AngioJet thrombectomy and JoStent coronary stent graft. (15152122)
2004
38
Surgical treatment of annuloaortic ectasia with coronary aneurysm and fistula. (11426789)
2001
39
Large atherosclerotic left main coronary aneurysm--a case report and review of the literature. (11515991)
2001
40
Intraseptal coronary aneurysm. (10969706)
2000
41
Transthoracic ultrasonic visualisation of coronary aneurysm, stenosis, and occlusion in Kawasaki disease. (10722537)
2000
42
Morphologic and functional assessment of coronary aneurysm after Kawasaki disease by repeated dipyridamole-loading coronary angiography. (9708673)
1998
43
Recurrent myocardial infarction caused by a giant coronary aneurysm. (9578359)
1998
44
Coronary aneurysm after bailout stent implantation: diagnosis of a false lumen with intravascular ultrasound. (9258484)
1997
45
Anticoagulant therapy during successful pregnancy and delivery in a Kawasaki disease patient with coronary aneurysm--a case report. (9070977)
1997
46
Development of a coronary aneurysm 6 months after stent implantation assessed by intracoronary ultrasound. (8721665)
1996
47
Long-term prognosis of giant coronary aneurysm in Kawasaki disease: an angiographic study. (3668739)
1987
48
Predictive factors of coronary aneurysm in Kawasaki disease--correlation between coronary arterial lesions and serum albumin, cholinesterase activity, prealbumin, retinol-binding protein and immature neutrophils. (3423065)
1987
49
Coronary aneurysm: isolated necrotizing angitis of a major coronary artery. Report of a case. (4149915)
1974
50
Coronary aneurysm with arteriovenous fistula. (13180479)
1954

Variations for Coronary Aneurysm

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Expression for genes affiliated with Coronary Aneurysm

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Expression patterns in normal tissues for genes affiliated with Coronary Aneurysm

Search GEO for disease gene expression data for Coronary Aneurysm.

Pathways for genes affiliated with Coronary Aneurysm

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Pathways related to Coronary Aneurysm according to GeneCards/GeneDecks:

(show all 30)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.4TNF, LTA
2
Show member pathways
9.4LTA, TNF
3
Show member pathways
9.4LTA, TNF
4
Show member pathways
Apoptosis Modulation and Signaling37
Apoptosis37
9.4LTA, TNF
59.4LTA, TNF
6
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
9.4LTA, TNF
7
Show member pathways
9.4LTA, TNF
8
Show member pathways
Apoptosis and survival TNFR1 signaling pathway60
TWEAK Signaling Pathway37
Apoptosis Modulation by HSP7037
HIV-1 Nef- Negative effector of Fas and TNF-alpha37
9.4LTA, TNF
9
Show member pathways
IL-9 Signaling Pathway37
Development Thrombopoietin regulated cell processes60
IL-7 Signaling Pathway37
Immune response IL 9 signaling pathway60
9.4TNF, LTA
10
Show member pathways
9.4LTA, TNF
119.4LTA, TNF
129.1LTA, IL10
139.1LTA, IL10
149.1TNF, IL10
15
Show member pathways
IL23-mediated signaling events37
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling37
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
9.1IL10, TNF
169.1IL10, TNF
179.1TNF, IL10
189.1TNF, IL10
19
Show member pathways
9.1IL10, TNF
209.1IL10, TNF
219.1IL10, TNF
229.1TNF, IL10
23
Show member pathways
8.6TNF, IL10, LTA
24
Show member pathways
IL27-mediated signaling events37
8.6LTA, IL10, TNF
25
Show member pathways
8.6LTA, IL10, TNF
268.6LTA, IL10, TNF
27
Show member pathways
8.6LTA, IL10, TNF
28
Show member pathways
8.6LTA, IL10, TNF
29
Show member pathways
8.6LTA, IL10, TNF
30
Show member pathways
8.6TNF, IL10, LTA

Compounds for genes affiliated with Coronary Aneurysm

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Compounds related to Coronary Aneurysm according to GeneCards/GeneDecks:

(show top 50)    (show all 76)
idCompoundScoreTop Affiliating Genes
1rantes4410.0IL10
2d-galactosamine449.7GPT, TNF
3nash449.7TNF, GPT
4cdp571449.5IL10, TNF
5interferon gamma449.5IL10, TNF
6gabexate mesilate449.5TNF, IL10
7blys449.5TNF, IL10
8ulinastatin449.5IL10, TNF
9mip 1alpha449.5TNF, IL10
10natalizumab44 1110.5IL10, TNF
115 aminosalicylic acid449.4IL10, TNF
12il-12449.4IL10, TNF
13adalimumab44 50 1111.4TNF, IL10
14indoleamine449.4IL10, TNF
15imiquimod44 61 28 1112.4TNF, IL10
16polymyxin b449.4TNF, IL10
176 mercaptopurine449.3GPT, IL10
18groalpha449.3IL10, TNF
19gm-csf44 2810.3TNF, IL10
208-isoprostane449.2IL10, TNF
21lamivudine44 50 1111.2GPT, IL10
22toxin-1449.1LTA, TNF, IL10
23cyclosporine50 1110.1LTA, IL10, TNF
24okt3449.0IL10, LTA, TNF
25lipoteichoic acid449.0LTA, IL10, TNF
26etanercept44 50 1111.0LTA, TNF, IL10
27il 10449.0IL10, TNF, LTA
28infliximab44 50 1111.0TNF, IL10, LTA
29polyinosinic-polycytidylic acid449.0IL10, TNF
30risperidone44 50 28 61 24 1114.0IL10, GPT
31pentoxifylline44 1110.0LTA, IL10, TNF
32tgf beta1449.0TNF, LTA, IL10
33endotoxin449.0LTA, IL10, TNF
34ionomycin449.0TNF, LTA, IL10
35calcitriol44 61 24 1112.0LTA, IL10, TNF
362,5-oligoadenylate448.9IL10, TNF, GPT
37atorvastatin44 50 28 24 1112.9GPT, TNF, IL10
38simvastatin44 50 61 28 24 1113.9TNF, IL10, GPT
39thyroxine44 249.9GPT, LTA, IL10
40tacrolimus44 50 1110.9IL10, TNF, GPT
41methotrexate50 44 1110.9IL10, TNF, GPT
42rolipram44 61 2810.8TNF, IL10
43vitamin d448.8GPT, LTA, IL10
44lactate448.8LTA, GPT, TNF
45pge2448.7LTA, IL10, TNF
46mycophenolate mofetil44 50 1110.4GPT, TNF, LTA, IL10
47ivig448.4IL10, LTA, GPT, TNF
48neopterin448.4LTA, TNF, IL10, GPT
49prednisolone44 28 1110.4GPT, IL10, LTA, TNF
50cyclosporin a44 28 6110.4IL10, GPT, LTA, TNF

GO Terms for genes affiliated with Coronary Aneurysm

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Cellular components related to Coronary Aneurysm according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.6LTA, IL10, TNF

Biological processes related to Coronary Aneurysm according to GeneCards/GeneDecks:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chronic inflammatory response to antigenic stimulusGO:0028769.7LTA, TNF
2positive regulation of humoral immune response mediated by circulating immunoglobulinGO:0029259.7TNF, LTA
3cellular amino acid biosynthetic processGO:0086529.6TNF, GPT
4defense response to Gram-positive bacteriumGO:0508309.5TNF, LTA
5positive regulation of interferon-gamma productionGO:0327299.5LTA, TNF
6humoral immune responseGO:0069599.4TNF, LTA
7response to hypoxiaGO:0016669.4TNF, LTA
8receptor biosynthetic processGO:0328009.4TNF, IL10
9negative regulation of cytokine secretion involved in immune responseGO:0027409.4IL10, TNF
10negative regulation of interleukin-6 productionGO:0327159.4TNF, IL10
11positive regulation of cytokine secretionGO:0507159.3IL10, TNF
12response to activityGO:0148239.3TNF, IL10
13response to glucocorticoidGO:0513849.0IL10, TNF
14negative regulation of growth of symbiont in hostGO:0441308.9IL10, LTA, TNF
15positive regulation of sequence-specific DNA binding transcription factor activityGO:0510918.8IL10, TNF
16response to drugGO:0424938.8TNF, LTA, IL10

Molecular functions related to Coronary Aneurysm according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:0051649.4LTA, TNF
2cytokine activityGO:0051258.3LTA, IL10, TNF

Products for genes affiliated with Coronary Aneurysm

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  • Antibodies
  • Proteins
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Sources for Coronary Aneurysm

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet