MCID: CRN006
MIFTS: 49

Coronary Aneurysm malady

Cardiovascular diseases category

Summaries for Coronary Aneurysm

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Wikipedia:64 Coronary artery aneurysm is an abnormal dilatation of part of the coronary artery. more...

MalaCards based summary: Coronary Aneurysm, also known as arteriovenous aneurysm of coronary vessels, is related to systemic lupus erythematosus and pneumonia. An important gene associated with Coronary Aneurysm is LDB3 (LIM domain binding 3), and among its related pathways are TRAF Pathway and Cellular Transformation by HTLV1. The compounds rantes and d-galactosamine have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and lymph node, and related mouse phenotypes are limbs/digits/tail and liver/biliary system.

Aliases & Classifications for Coronary Aneurysm

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Coronary Aneurysm, Aliases & Descriptions:

Name: Coronary Aneurysm 9 11 61
Arteriovenous Aneurysm of Coronary Vessels 9 61
 
Aneurysmal Lesion of Coronary Artery 9 61
Aneurysm of Coronary Vessels 9 61


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


External Ids:

Disease Ontology9 DOID:3362
MeSH34 D003323
SNOMED-CT56 373139003, 50570003
ICD9CM28 414.11

Related Diseases for Coronary Aneurysm

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Diseases related to Coronary Aneurysm via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 83)
idRelated DiseaseScoreTop Affiliating Genes
1systemic lupus erythematosus30.2IL10, LTA, TNF
2pneumonia29.9IL10, TNF
3arthritis29.8LTA, IL10, TNF
4rheumatoid arthritis29.7TNF, LTA, IL10
5aneurysm11.2
6kawasaki disease10.9
7myocardial infarction10.7
8acute myocardial infarction10.6
9blau syndrome10.4TNF
10psoriatic arthritis10.4TNF
11polyarteritis nodosa10.3
12lupus erythematosus10.3
13leishmaniasis10.3IL10
14toxic shock syndrome10.2LTA, TNF
15arteriovenous fistula10.2
16polycystic kidney disease10.2
17churg-strauss syndrome10.2
18kidney disease10.2
19hypereosinophilic syndrome10.2
20pulmonary sarcoidosis10.2LTA, TNF
21juvenile rheumatoid arthritis10.2LTA, TNF
22adult respiratory distress syndrome10.2TNF, LTA
23behcet's disease10.2TNF, LTA
24alcoholic hepatitis10.1GPT, TNF
25sarcoidosis10.1TNF, LTA
26hypertriglyceridemia10.1GPT, LTA
27primary biliary cirrhosis10.1LTA, GPT
28galactosemia10.1TNF, IL10
29selective iga deficiency disease10.1IL10, LTA
30lepromatous leprosy10.1LTA, IL10
31visceral leishmaniasis10.1IL10, LTA
32cerebral malaria10.1TNF, IL10
33demyelinating disease10.0TNF, IL10
34coronary artery anomaly10.0LTA, LDB3
35familial hypercholesterolemia10.0
36takayasu's arteritis10.0
37marfan syndrome10.0
38cardiac tamponade10.0
39supravalvular aortic stenosis10.0
40silent myocardial infarction10.0
41lyme disease10.0
42coronary thrombosis10.0
43neurofibromatosis10.0
44intracranial aneurysm10.0
45hemopericardium10.0
46pericardial effusion10.0
47pericarditis10.0
48aortic coarctation10.0
49chronic active epstein-barr virus infection10.0
50fibromuscular dysplasia10.0

Graphical network of the top 20 diseases related to Coronary Aneurysm:



Diseases related to coronary aneurysm

Symptoms for Coronary Aneurysm

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Drugs & Therapeutics for Coronary Aneurysm

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Drug clinical trials:

Search ClinicalTrials for Coronary Aneurysm

Search NIH Clinical Center for Coronary Aneurysm

Genetic Tests for Coronary Aneurysm

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Anatomical Context for Coronary Aneurysm

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MalaCards organs/tissues related to Coronary Aneurysm:

32
Heart, Kidney, Lymph node, Endothelial, Neutrophil

Animal Models for Coronary Aneurysm or affiliated genes

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MGI Mouse Phenotypes related to Coronary Aneurysm:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.6LTA, IL10, TNF
2MP:00053708.3LTA, IL10, TNF
3MP:00053888.3LTA, IL10, LDB3, TNF
4MP:00053858.2TNF, LDB3, IL10, LTA
5MP:00053788.2LTA, IL10, LDB3, TNF
6MP:00053868.1TNF, LDB3, IL10, LTA

Publications for Coronary Aneurysm

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Articles related to Coronary Aneurysm:

(show top 50)    (show all 234)
idTitleAuthorsYear
1
Massive coronary aneurysm after multiple percutaneous interventions: an iatrogenic or unpreventable disaster? (24456720)
2014
2
Acute coronary thrombosis and multiple coronary aneurysms in a 22-year-old man with the human immunodeficiency virus. (24808786)
2014
3
Coronary Aneurysm After Paclitaxel-eluting Balloon Angioplasty. (24841291)
2014
4
A Case of Kawasaki Disease with Coronary Aneurysm Responding to the 4th IVIG Treatment. (25161773)
2014
5
Bilateral giant coronary aneurysms in Kawasaki disease: how difficult can it be? (24218442)
2013
6
Bentall procedure for an adult patient with supravalvular aortic stenosis and coronary aneurysms. (23879341)
2013
7
Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction in a Pediatric Patient with Giant Coronary Aneurysm Due to Kawasaki Disease. (23601472)
2013
8
Coronary Artery Bypass Grafting in a Patient with Polyarteritis Nodosa Presenting with Acute Myocardial Infarction and Multiple Coronary Aneurysms. (23995351)
2013
9
National Japanese survey of thrombolytic therapy selection for coronary aneurysm: Intracoronary thrombolysis or intravenous coronary thrombolysis in patients with Kawasaki disease. (23919576)
2013
10
Intracoronary thrombus in an infant with Kawasaki disease and giant coronary aneurysm. (23368954)
2013
11
Rare insight into the rapid evolution of a coronary aneurysm and fistula. (24076292)
2013
12
Reversible stenosis of the saphenous vein graft compressed by giant coronary aneurysm in Kawasaki disease. (23660427)
2013
13
Coronary aneurysm formation following biodegradable polymer drug-eluting stent implantation. (22257689)
2012
14
Rapidly evolving coronary aneurysm in a patient with rheumatoid arthritis. (21403892)
2011
15
Myocardial infarction in a youngster due to giant coronary aneurysm. (21351229)
2011
16
Coronary aneurysm with double right coronary artery and fistula. (21241866)
2011
17
Very late coronary aneurysm formation with subsequent stent thrombosis secondary to drug-eluting stent. (22088549)
2011
18
Case images: giant coronary aneurysm accompanied by a coronary artery fistula. (20935441)
2010
19
Impressive combination of multiple sinus valsalvae and coronary aneurysms due to hypereosinophilic syndrome. (20971227)
2010
20
Natural history of a giant coronary aneurysm with spontaneous dissection. (20014206)
2009
21
Giant coronary aneurysm in a patient with systemic lupus erythematosus. (19687588)
2009
22
Left anterior descending coronary aneurysm. (19515889)
2009
23
Cardiovascular images. Giant right coronary aneurysm to left ventricular fistula. (19808583)
2009
24
Case report: Giant coronary aneurysm caused by Kawasaki disease: follow-up with echocardiography and multidetector CT angiography. (18344266)
2008
25
Coronary aneurysm in Lyme Disease: treatment by covered stent. (17692941)
2008
26
Coronary aneurysm formation in a patient early after everolimus-eluting stent implantation. (18460723)
2008
27
Rapid development of late stent malappositon and coronary aneurysm following implantation of a paclitaxel-eluting coronary stent. (17442215)
2007
28
Late stent thrombosis associated with coronary aneurysm formation after sirolimus-eluting stent implantation. (17404416)
2007
29
Development of coronary aneurysm after drug-eluting stent implantation. (17283357)
2007
30
Giant coronary aneurysm following drug-eluting stent implantation presenting as fever of unknown origin. (17620677)
2007
31
Noninvasive evaluation of left circumflex coronary aneurysm by real-time three-dimensional echocardiography. (15908280)
2006
32
Images in cardiology: giant coronary aneurysm in the septal branch. (16287752)
2005
33
Polytetrafluoroethylene stent deployment for a left anterior descending coronary aneurysm complicated by late acute anterior myocardial infarction. (16061748)
2005
34
Percutaneous treatment of a large coronary aneurysm using the self-expandable Symbiot PTFE-covered stent. (15302758)
2004
35
Elevated levels of matrix metalloprotein-3 in patients with coronary aneurysm: A case control study. (15482602)
2004
36
Stent implantation for coronary aneurysm with edge stenosis: angiographic and intravascular analysis. (15152166)
2004
37
Treatment of coronary aneurysm in acute myocardial infarction with AngioJet thrombectomy and JoStent coronary stent graft. (15152122)
2004
38
Surgical treatment of annuloaortic ectasia with coronary aneurysm and fistula. (11426789)
2001
39
Large atherosclerotic left main coronary aneurysm--a case report and review of the literature. (11515991)
2001
40
Intraseptal coronary aneurysm. (10969706)
2000
41
Transthoracic ultrasonic visualisation of coronary aneurysm, stenosis, and occlusion in Kawasaki disease. (10722537)
2000
42
Morphologic and functional assessment of coronary aneurysm after Kawasaki disease by repeated dipyridamole-loading coronary angiography. (9708673)
1998
43
Recurrent myocardial infarction caused by a giant coronary aneurysm. (9578359)
1998
44
Coronary aneurysm after bailout stent implantation: diagnosis of a false lumen with intravascular ultrasound. (9258484)
1997
45
Anticoagulant therapy during successful pregnancy and delivery in a Kawasaki disease patient with coronary aneurysm--a case report. (9070977)
1997
46
Development of a coronary aneurysm 6 months after stent implantation assessed by intracoronary ultrasound. (8721665)
1996
47
Long-term prognosis of giant coronary aneurysm in Kawasaki disease: an angiographic study. (3668739)
1987
48
Predictive factors of coronary aneurysm in Kawasaki disease--correlation between coronary arterial lesions and serum albumin, cholinesterase activity, prealbumin, retinol-binding protein and immature neutrophils. (3423065)
1987
49
Coronary aneurysm: isolated necrotizing angitis of a major coronary artery. Report of a case. (4149915)
1974
50
Coronary aneurysm with arteriovenous fistula. (13180479)
1954

Variations for Coronary Aneurysm

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Expression for genes affiliated with Coronary Aneurysm

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Expression patterns in normal tissues for genes affiliated with Coronary Aneurysm

Search GEO for disease gene expression data for Coronary Aneurysm.

Pathways for genes affiliated with Coronary Aneurysm

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Pathways related to Coronary Aneurysm according to GeneCards/GeneDecks:

(show all 30)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.4TNF, LTA
2
Show member pathways
9.4LTA, TNF
3
Show member pathways
9.4LTA, TNF
4
Show member pathways
Apoptosis Modulation and Signaling37
Apoptosis37
9.4LTA, TNF
59.4LTA, TNF
6
Show member pathways
Transcription NF kB signaling pathway59
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response59
9.4LTA, TNF
7
Show member pathways
9.4LTA, TNF
8
Show member pathways
Apoptosis and survival TNFR1 signaling pathway59
TWEAK Signaling Pathway37
Apoptosis Modulation by HSP7037
HIV-1 Nef- Negative effector of Fas and TNF-alpha37
9.4LTA, TNF
9
Show member pathways
IL-9 Signaling Pathway37
Development Thrombopoietin regulated cell processes59
IL-7 Signaling Pathway37
Immune response IL 9 signaling pathway59
9.4TNF, LTA
10
Show member pathways
9.4LTA, TNF
119.4LTA, TNF
129.1LTA, IL10
139.1LTA, IL10
149.1TNF, IL10
15
Show member pathways
IL23-mediated signaling events37
Immune response IL 10 signaling pathway59
Angiopoietin receptor Tie2-mediated signaling37
Development PDGF signaling via STATs and NF kB59
Development Angiopoietin Tie2 signaling59
9.1IL10, TNF
169.1IL10, TNF
179.1TNF, IL10
189.1TNF, IL10
19
Show member pathways
9.1IL10, TNF
209.1IL10, TNF
219.1IL10, TNF
229.1TNF, IL10
23
Show member pathways
8.6TNF, IL10, LTA
24
Show member pathways
IL27-mediated signaling events37
8.6LTA, IL10, TNF
25
Show member pathways
8.6LTA, IL10, TNF
268.6LTA, IL10, TNF
27
Show member pathways
8.6LTA, IL10, TNF
28
Show member pathways
8.6LTA, IL10, TNF
29
Show member pathways
8.6LTA, IL10, TNF
30
Show member pathways
8.6TNF, IL10, LTA

Compounds for genes affiliated with Coronary Aneurysm

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Compounds related to Coronary Aneurysm according to GeneCards/GeneDecks:

(show top 50)    (show all 76)
idCompoundScoreTop Affiliating Genes
1rantes4410.0IL10
2d-galactosamine449.7TNF, GPT
3nash449.7GPT, TNF
4cdp571449.5IL10, TNF
5interferon gamma449.5IL10, TNF
6blys449.5IL10, TNF
7gabexate mesilate449.5IL10, TNF
8ulinastatin449.5IL10, TNF
9mip 1alpha449.5IL10, TNF
10natalizumab44 1210.5IL10, TNF
115 aminosalicylic acid449.4TNF, IL10
12il-12449.4TNF, IL10
13adalimumab44 50 1211.4IL10, TNF
14indoleamine449.4IL10, TNF
15imiquimod44 60 29 1212.4TNF, IL10
16polymyxin b449.4IL10, TNF
176 mercaptopurine449.3IL10, GPT
18groalpha449.3IL10, TNF
19gm-csf44 2910.3TNF, IL10
208-isoprostane449.2IL10, TNF
21lamivudine44 50 1211.2IL10, GPT
22toxin-1449.1TNF, IL10, LTA
23cyclosporine50 1210.1LTA, IL10, TNF
24okt3449.0LTA, IL10, TNF
25lipoteichoic acid449.0TNF, IL10, LTA
26etanercept44 50 1211.0TNF, IL10, LTA
27il 10449.0LTA, IL10, TNF
28infliximab44 50 1211.0LTA, IL10, TNF
29polyinosinic-polycytidylic acid449.0IL10, TNF
30risperidone44 50 29 60 25 1214.0IL10, GPT
31pentoxifylline44 1210.0TNF, IL10, LTA
32tgf beta1449.0TNF, IL10, LTA
33endotoxin449.0TNF, IL10, LTA
34ionomycin449.0LTA, IL10, TNF
35calcitriol44 60 25 1212.0TNF, IL10, LTA
362,5-oligoadenylate448.9IL10, TNF, GPT
37atorvastatin44 50 29 25 1212.9GPT, TNF, IL10
38simvastatin44 50 60 29 25 1213.9IL10, TNF, GPT
39thyroxine44 259.9LTA, IL10, GPT
40tacrolimus44 50 1210.9IL10, TNF, GPT
41methotrexate50 44 1210.9GPT, TNF, IL10
42rolipram44 60 2910.8IL10, TNF
43vitamin d448.8LTA, IL10, GPT
44lactate448.8GPT, TNF, LTA
45pge2448.7LTA, IL10, TNF
46mycophenolate mofetil44 50 1210.4LTA, IL10, TNF, GPT
47ivig448.4GPT, TNF, IL10, LTA
48neopterin448.4GPT, TNF, IL10, LTA
49prednisolone44 29 1210.4LTA, IL10, TNF, GPT
50cyclosporin a44 29 6010.4LTA, IL10, TNF, GPT

GO Terms for genes affiliated with Coronary Aneurysm

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Cellular components related to Coronary Aneurysm according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.6LTA, IL10, TNF

Biological processes related to Coronary Aneurysm according to GeneCards/GeneDecks:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chronic inflammatory response to antigenic stimulusGO:0028769.7LTA, TNF
2positive regulation of humoral immune response mediated by circulating immunoglobulinGO:0029259.7LTA, TNF
3cellular amino acid biosynthetic processGO:0086529.6TNF, GPT
4defense response to Gram-positive bacteriumGO:0508309.5LTA, TNF
5positive regulation of interferon-gamma productionGO:0327299.5TNF, LTA
6humoral immune responseGO:0069599.4LTA, TNF
7response to hypoxiaGO:0016669.4LTA, TNF
8receptor biosynthetic processGO:0328009.4IL10, TNF
9negative regulation of cytokine secretion involved in immune responseGO:0027409.4TNF, IL10
10negative regulation of interleukin-6 productionGO:0327159.4IL10, TNF
11positive regulation of cytokine secretionGO:0507159.3IL10, TNF
12response to activityGO:0148239.3IL10, TNF
13response to glucocorticoidGO:0513849.0IL10, TNF
14negative regulation of growth of symbiont in hostGO:0441308.9LTA, IL10, TNF
15positive regulation of sequence-specific DNA binding transcription factor activityGO:0510918.8IL10, TNF
16response to drugGO:0424938.8TNF, IL10, LTA

Molecular functions related to Coronary Aneurysm according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor receptor bindingGO:0051649.4LTA, TNF
2cytokine activityGO:0051258.3LTA, IL10, TNF

Products for genes affiliated with Coronary Aneurysm

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Sources for Coronary Aneurysm

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet