MCID: CRN006
MIFTS: 32

Coronary Aneurysm

Categories: Cardiovascular diseases

Aliases & Classifications for Coronary Aneurysm

MalaCards integrated aliases for Coronary Aneurysm:

Name: Coronary Aneurysm 12 41 14 69
Arteriovenous Aneurysm of Coronary Vessels 12
Aneurysmal Lesion of Coronary Artery 12
Aneurysm of Coronary Vessels 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3362
ICD10 32 I25.41
ICD9CM 34 414.11
MeSH 41 D003323
SNOMED-CT 64 373139003 50570003
UMLS 69 C0010051

Summaries for Coronary Aneurysm

MalaCards based summary : Coronary Aneurysm, also known as arteriovenous aneurysm of coronary vessels, is related to coronary artery aneurysm and aneurysm. An important gene associated with Coronary Aneurysm is TET1 (Tet Methylcytosine Dioxygenase 1). The drugs Aspirin and Clopidogrel have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and kidney.

Related Diseases for Coronary Aneurysm

Diseases related to Coronary Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 coronary artery aneurysm 11.0
2 aneurysm 10.8
3 kawasaki disease 10.5
4 myocardial infarction 10.3
5 acute myocardial infarction 10.2
6 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 10.2
7 thrombosis 10.2
8 systemic lupus erythematosus 9.9
9 polyarteritis nodosa, childhood-onset 9.9
10 lupus erythematosus 9.9
11 polyarteritis nodosa 9.9
12 neurofibromatosis, type iv, of riccardi 9.7
13 arteriovenous fistula 9.7
14 atrial fibrillation 9.7
15 hemopericardium 9.7
16 allergic hypersensitivity disease 9.7
17 churg-strauss syndrome 9.7
18 kidney disease 9.7
19 hypereosinophilic syndrome 9.7
20 polycystic kidney disease 9.7
21 coronary arterial fistulas 9.7
22 cardiac conduction defect 9.6
23 fibromuscular dysplasia 9.6
24 hypercholesterolemia, familial 9.6
25 marfan syndrome 9.6
26 rheumatoid arthritis 9.6
27 supravalvular aortic stenosis 9.6
28 hypercholesterolemia, autosomal dominant, 3 9.6
29 melioidosis 9.6
30 arthritis 9.6
31 intracranial aneurysm 9.6
32 cardiac tamponade 9.6
33 lyme disease 9.6
34 pericardial effusion 9.6
35 coronary thrombosis 9.6
36 pericarditis 9.6
37 coronary stenosis 9.6
38 pneumonia 9.6
39 silent myocardial infarction 9.6
40 acquired immunodeficiency syndrome 9.6
41 mediastinitis 9.6
42 autosomal dominant polycystic kidney disease 9.6
43 aortic coarctation 9.6
44 chronic active epstein-barr virus infection 9.6
45 microscopic polyangiitis 9.6
46 syncope 9.6
47 endotheliitis 9.6
48 heart aneurysm 8.0 CA8 CLMP IFNAR2 LDB3 TET1 UPK2

Graphical network of the top 20 diseases related to Coronary Aneurysm:



Diseases related to Coronary Aneurysm

Symptoms & Phenotypes for Coronary Aneurysm

Drugs & Therapeutics for Coronary Aneurysm

Drugs for Coronary Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 49)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
2
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
3
Ticlopidine Approved Phase 4 55142-85-3 5472
4 Antirheumatic Agents Phase 4,Phase 2
5 Analgesics Phase 4
6 Analgesics, Non-Narcotic Phase 4
7 Anti-Inflammatory Agents Phase 4
8 Anti-Inflammatory Agents, Non-Steroidal Phase 4
9 Antipyretics Phase 4
10 Cyclooxygenase Inhibitors Phase 4
11 Cytochrome P-450 Enzyme Inhibitors Phase 4
12 Fibrinolytic Agents Phase 4
13 Neurotransmitter Agents Phase 4
14 Peripheral Nervous System Agents Phase 4
15 Platelet Aggregation Inhibitors Phase 4
16 Purinergic P2 Receptor Antagonists Phase 4
17 Purinergic P2Y Receptor Antagonists Phase 4
18
Paclitaxel Approved, Vet_approved Phase 2, Phase 3 33069-62-4 36314
19 Albumin-Bound Paclitaxel Phase 2, Phase 3
20 Antimitotic Agents Phase 2, Phase 3
21 Antineoplastic Agents, Phytogenic Phase 2, Phase 3
22
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
23
Infliximab Approved Phase 2 170277-31-3
24 Anticholesteremic Agents Phase 2
25 Antimetabolites Phase 2
26 Atorvastatin Calcium Phase 2 134523-03-8
27 Calcium, Dietary Phase 2
28 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
29 Hypolipidemic Agents Phase 2
30 Lipid Regulating Agents Phase 2
31 Antibodies Phase 2
32 gamma-Globulins Phase 2
33 Immunoglobulins Phase 2
34 Immunoglobulins, Intravenous Phase 2
35 Interleukin 1 Receptor Antagonist Protein Phase 2
36 Rho(D) Immune Globulin Phase 2
37 Anti-Bacterial Agents Phase 2
38 Anti-Infective Agents Phase 2
39 Antimalarials Phase 2
40 Antiparasitic Agents Phase 2
41 Antiprotozoal Agents Phase 2
42 Dermatologic Agents Phase 2
43 Gastrointestinal Agents Phase 2
44
Diltiazem Approved, Investigational 42399-41-7 39186
45
Adenosine Approved, Investigational 58-61-7 60961
46
Dobutamine Approved 34368-04-2 36811
47 Antihypertensive Agents
48 calcium channel blockers
49 Vasodilator Agents

Interventional clinical trials:

(show all 16)

# Name Status NCT ID Phase Drugs
1 Trial to Assess the Efficacy of Combination Formula of Aspirin Plus Clopidogrel in Patients With Coronary Stent Completed NCT02410083 Phase 4 Clopirin 1;Clopidogrel-Aspirin(co-administration) 1;Clopirin 2;Clopidogrel-Aspirin(co-administration) 2
2 Trial of Pulse Steroid Therapy in Kawasaki Disease--Pediatric Heart Network Completed NCT00132080 Phase 3 Steroids
3 Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stents to Treat De Novo Coronary Lesions Completed NCT00301522 Phase 2, Phase 3
4 Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stent in the Treatment of In-Stent Restenosis Completed NCT00287573 Phase 2, Phase 3
5 Trial of Atorvastatin on the Persistent Coronary Aneurysm in Children With Kawasaki Disease Unknown status NCT02114099 Phase 2 Atorvastatin
6 Anakinra and Kawasaki Disease Unknown status NCT02390596 Phase 2 Anakinra
7 Prevention of Coronary Aneurysms in Kawasaki Syndrome Completed NCT00000520 Phase 2 immunoglobulins, intravenous;aspirin
8 Doxycycline Treatment to Prevent Progressive Coronary Artery Dilation in Children With Kawasaki Disease Recruiting NCT01917721 Phase 2 Doxycycline;Standard care
9 Study of Efficacy and Safety of Canakinumab in Pediatric Patients With Kawasaki Disease Withdrawn NCT02980263 Phase 2 Canakinumab
10 Endothelial Function in Patients With Ectatic Compared to Normal Coronary Arteries Unknown status NCT00548457
11 Coronary Artery Aneurysm Registry Completed NCT02563626
12 Effect of Diltiazem on Coronary Artery Ectasia Completed NCT02024919 intracoronary administration of diltiazem;intracoronary injection of 5 mL saline
13 Prevalence and Early Markers of Atherosclerosis in Adults With a History of Kawasaki Disease Completed NCT01440075
14 Assessment Of Total Coronary Circulation Time Using TIMI Frame Count Method (TCCT-TIMI) Recruiting NCT02818127
15 Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method Recruiting NCT02831153
16 Etiology Study of Kawasaki Disease Recruiting NCT00154596

Search NIH Clinical Center for Coronary Aneurysm

Cochrane evidence based reviews: coronary aneurysm

Genetic Tests for Coronary Aneurysm

Anatomical Context for Coronary Aneurysm

MalaCards organs/tissues related to Coronary Aneurysm:

38
Heart, Endothelial, Kidney, Neutrophil, Lymph Node

Publications for Coronary Aneurysm

Articles related to Coronary Aneurysm:

(show top 50) (show all 284)
# Title Authors Year
1
Giant coronary aneurysm culprit of an acute coronary syndrome. ( 29317116 )
2018
2
Extraluminal Migration of a Drug-Eluting Stent Into a Thrombosed Coronary Aneurysm With Preserved Antegrade FlowA in the Right Coronary Artery. ( 28365264 )
2017
3
Long-Term Prognosis for Patients with Kawasaki Disease Complicated by Large Coronary Aneurysm (diameter a8Y6 mm). ( 28765744 )
2017
4
Bioresorbable Vascular Scaffold Coronary Aneurysm and Thrombosis: Farewell to the Current Bioresorbable Vascular Scaffolds? ( 29086732 )
2017
5
Very Late Stent Migration Within a GiantA Coronary Aneurysm in a Patient WithA Kawasaki Disease: Assessment With Multidetector Computed Tomography. ( 28823775 )
2017
6
Retrospective study of the impact of unrecognised Kawasaki disease, coronary aneurysm and ectasia. ( 28818354 )
2017
7
Giant coronary aneurysm exposed on routine echocardiogram. ( 29020369 )
2017
8
Stenotic false lumen as inflow of coronary aneurysm and full-metal jacket. ( 28688710 )
2017
9
Coronary Aneurysm Formation After Bioresorbable Vascular Scaffold Implantation Resulting in Acute Myocardial Infarction. ( 28512285 )
2017
10
Angioscopic observation of an atherosclerotic coronary aneurysm without yellow plaque. ( 28739628 )
2017
11
Lesion preparation with cutting balloon angioplasty is associated with coronary aneurysm formation in polylactide bioresorbable vascular scaffold implantation. ( 28760724 )
2017
12
Mega-giant coronary aneurysm: antithrombotic therapy is an option. ( 28821483 )
2017
13
Coronary aneurysm formation following bare-metal stent implantation: an optical coherence tomography evaluation. ( 28102661 )
2017
14
Nationwide Survey of Patients With Giant Coronary Aneurysm Secondary to Kawasaki Disease 1999-2010 in Japan. ( 28855435 )
2017
15
"Giant within a giant": a case of typical Kawasaki disease with a giant coronary aneurysm and a large coronary thrombus - a rare case report. ( 28835313 )
2017
16
Importance of detailed distribution of branches in giant coronary aneurysm. ( 28186232 )
2017
17
Long-Term Outcome of Kawasaki Disease Complicated by a Large Coronary Aneurysm. ( 28765734 )
2017
18
Giant coronary aneurysm management with Viabahn covered stent. ( 28483590 )
2017
19
ST-elevation myocardial infarction in a young adult secondary to giant coronary aneurysm thrombosis: an important sequela of Kawasaki disease and a management challenge. ( 26791126 )
2016
20
Giant coronary aneurysm in a patient with non-ST myocardial infarction. ( 27044918 )
2016
21
Importance of detailed distribution of branches in giant coronary aneurysm. ( 27634923 )
2016
22
Corticosteroid Therapy Might be Associated with the Development of Coronary Aneurysm in Children with Kawasaki Disease. ( 27064036 )
2016
23
Giant Coronary Aneurysms in a one-month-old Infant with Kawasaki Disease. ( 27641973 )
2016
24
Coronary aneurysm without malapposition after bioresorbable vascular scaffold implantation. ( 27173862 )
2016
25
Coronary Stenosis Associated with a Giant Coronary Aneurysm. ( 26626563 )
2016
26
Bilateral coronary artery fistulas with a giant coronary aneurysm complicated by aneurysm rupture: A case report. ( 27861394 )
2016
27
A 5-year-old boy with only fever and giant coronary aneurysms: the enigma of Kawasaki disease? ( 27154559 )
2016
28
Biovascular scaffolds and reversible coronary aneurysm. ( 27070996 )
2016
29
Massive left main coronary aneurysm presenting as trepopnoea. ( 27594368 )
2016
30
Multiple coronary aneurysms in a young adult with acquired immunodeficiency syndrome. ( 27168940 )
2016
31
A Loeys-Dietz patient with a transatlantic odyssey: repeated aortic root surgery ending with a huge left main coronary aneurysm. ( 27624358 )
2016
32
An unexpected huge coronary aneurysm. ( 27753603 )
2016
33
Managing bioabsorbable vascular scaffold failure: combined scaffold restenosis and late-acquired coronary aneurysm treated with self-expandable stent. ( 25936494 )
2015
34
Giant coronary aneurysm caused by Kawasaki disease: consistency between catheter angiography and electrocardiogram gated dual-source computed tomography angiography. ( 26770226 )
2015
35
Coronary Aneurysm and Stent Fracture Following Stenting of a Myocaridal Bridge. ( 25573225 )
2015
36
Recurrent Myocardial Infarctions Due toA Thrombosis of a Coronary Aneurysm inA Neurofibromatosis Type 1: Is Antiplatelet Treatment Enough? ( 25819181 )
2015
37
Multimodality Imaging of Giant Right Coronary Aneurysm and Postsurgical Coronary Artery Inflammation. ( 26149430 )
2015
38
Giant right coronary aneurysm untreatable by percutaneous intervention. ( 26481179 )
2015
39
Acute Myocardial Infarction That Resulted From Poor Adherence to Medical Treatment for Giant Coronary Aneurysm. ( 26155999 )
2015
40
Giant coronary aneurysm diagnosed as incidental mediastinal mass. ( 25616825 )
2015
41
A giant coronary aneurysm formed after coronary artery bypass grafting. ( 25634861 )
2015
42
Intracoronary blood sampling with a microcatheter for the diagnosis of giant infective coronary aneurysm: Melioidosis of coronary artery mycotic aneurysm. ( 25863294 )
2015
43
Surgical Resection of a Giant Coronary Aneurysm. ( 26046882 )
2015
44
A giant coronary aneurysm on the right coronary artery in a 16-year-old patient. ( 26574772 )
2015
45
Giant coronary aneurysm secondary to coronary-atrial fistula. ( 25660938 )
2015
46
A Case of Kawasaki Disease with Coronary Aneurysm Responding to the 4th IVIG Treatment. ( 25161773 )
2014
47
A giant coronary aneurysm induced by rotational atherectomy in a patient with unrecognized familial hypercholesterolemia. ( 25150774 )
2014
48
360 degrees out of trouble: a novel wiring technique required in management of acute occlusion of a giant coronary aneurysm. ( 25086844 )
2014
49
Postoperative coronary aneurysm treated with endovascular coiling. ( 25193191 )
2014
50
Massive coronary aneurysm after multiple percutaneous interventions: an iatrogenic or unpreventable disaster? ( 24456720 )
2014

Variations for Coronary Aneurysm

Expression for Coronary Aneurysm

Search GEO for disease gene expression data for Coronary Aneurysm.

Pathways for Coronary Aneurysm

GO Terms for Coronary Aneurysm

Sources for Coronary Aneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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