MCID: CRN074
MIFTS: 46

Coronary Artery Aneurysm malady

Categories: Rare diseases, Cardiovascular diseases, Fetal diseases

Aliases & Classifications for Coronary Artery Aneurysm

Aliases & Descriptions for Coronary Artery Aneurysm:

Name: Coronary Artery Aneurysm 50
Coronary Artery Aneurysms 52
Coronary Aneurysm 69

Classifications:



External Ids:

ICD10 33 I25.4

Summaries for Coronary Artery Aneurysm

MalaCards based summary : Coronary Artery Aneurysm, also known as coronary artery aneurysms, is related to rheumatoid arthritis and congenital coronary artery aneurysm. An important gene associated with Coronary Artery Aneurysm is VCAM1 (Vascular Cell Adhesion Molecule 1), and among its related pathways/superpathways are Integrin Pathway and Degradation of the extracellular matrix. The drugs Ramipril and Valsartan have been mentioned in the context of this disorder. Affiliated tissues include heart, t cells and lymph node, and related phenotypes are homeostasis/metabolism and immune system

Wikipedia : 71 Coronary artery aneurysm is an abnormal dilatation of part of the coronary... more...

Related Diseases for Coronary Artery Aneurysm

Diseases in the Coronary Artery Aneurysm family:

Congenital Coronary Artery Aneurysm

Diseases related to Coronary Artery Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
id Related Disease Score Top Affiliating Genes
1 rheumatoid arthritis 29.2 CCL2 MMP1 MMP13 MMP3 VCAM1
2 congenital coronary artery aneurysm 12.2
3 kawasaki disease 11.6
4 aneurysm 11.0
5 myocardial infarction 10.4
6 symmastia 10.3 MMP1 MMP3
7 acute myocardial infarction 10.2
8 coronary artery dissection, spontaneous 10.2
9 kleptomania 10.2 MMP1 MMP3 MMP7
10 linear porokeratosis 10.2 MMP1 MMP12 MMP7
11 cystic lymphangioma 10.2 MMP1 MMP3 MMP7
12 arteriovenous fistula 10.1
13 synovium cancer 10.1 MMP1 MMP13 MMP3 VCAM1
14 thrombosis 10.1
15 exophthalmic ophthalmoplegia 10.1 ADIPOQ LEP VCAM1
16 acrocephalopolydactyly 10.1 ADIPOQ LEP RETN
17 malignant perineurioma 10.1 ADIPOQ LEP RETN
18 cardiac tamponade 10.1
19 not otherwise specified 3-mga-uria type 10.1 ADIPOQ LEP RETN
20 cataract 20, multiple types 10.0 ADIPOQ LEP RETN
21 coronary arterial fistulas 10.0
22 bone angioendothelial sarcoma 10.0 CCL2 MMP1 MMP13 MMP3
23 mucopolysaccharidosis iii 10.0 ADIPOQ LEP RETN
24 mucinoses 10.0 ADIPOQ LEP RETN VCAM1
25 chronic tic disorder 10.0 ADIPOQ LEP VCAM1
26 mediastinitis 10.0
27 thymus clear cell carcinoma 10.0 ADIPOQ LEP RETN
28 autistic disorder 10.0 CCL2 MMP1 MMP13 MMP3
29 bare lymphocyte syndrome, type i 10.0 ADIPOQ CCL2 VCAM1
30 mixed ductal-endocrine carcinoma 9.9 CCL2 MMP1 MMP12 MMP13 MMP3
31 endocarditis 9.9
32 antidepressant type abuse 9.9 ADIPOQ LEP RETN
33 autoimmune-related retinopathy and optic neuropathy 9.9 ADIPOQ CCL2 MMP3 VCAM1
34 adrenal adenoma 9.9 ADIPOQ CCL2 LEP RETN
35 aortic aneurysm, familial thoracic 6 9.9 CCL17 CCL2 MMP1 MMP7 VCAM1
36 body dysmorphic disorder 9.9 ADIPOQ CCL2 LEP RETN
37 neurofibromatosis 9.9
38 pericarditis 9.9 ADIPOQ CCL2 RETN VCAM1
39 hemolytic anemia, cd59-mediated, with or without immune-mediated polyneuropathy 9.8 ADIPOQ LEP RETN
40 polyarteritis nodosa 9.8
41 patent ductus arteriosus 9.8
42 aneurysm of sinus of valsalva 9.8
43 atherosclerosis 9.8
44 cerebritis 9.8
45 systemic lupus erythematosus 9.8
46 coronary artery disease 9.8
47 aortic aneurysm 9.8
48 aortitis 9.8
49 sudden cardiac death 9.8
50 artery disease 9.8

Graphical network of the top 20 diseases related to Coronary Artery Aneurysm:



Diseases related to Coronary Artery Aneurysm

Symptoms & Phenotypes for Coronary Artery Aneurysm

MGI Mouse Phenotypes related to Coronary Artery Aneurysm:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.73 ADIPOQ BAG6 ITPR3 LEP MMP1 MMP12
2 immune system MP:0005387 9.36 ABHD16A ADIPOQ CCL17 CCL2 LEP MMP1

Drugs & Therapeutics for Coronary Artery Aneurysm

Drugs for Coronary Artery Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 145)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ramipril Approved Phase 4 87333-19-5 5362129
2
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
3
Ticlopidine Approved Phase 4 55142-85-3 5472
4
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 22916-47-8 4189
5
Everolimus Approved Phase 4,Phase 3,Phase 1,Phase 2 159351-69-6 6442177
6
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 53123-88-9 5284616 6436030 46835353
7
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
8
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
9
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
10
Eplerenone Approved Phase 4 107724-20-9 150310 443872
11
Clopidogrel Approved, Nutraceutical Phase 4 120202-66-6, 113665-84-2 60606
12
Angiotensin II Phase 4,Phase 3 68521-88-0, 11128-99-7 65143 172198
13 Rosuvastatin Calcium Phase 4 147098-20-2
14
protease inhibitors Phase 4
15 Neurotransmitter Agents Phase 4,Phase 3
16 HIV Protease Inhibitors Phase 4
17 Cytochrome P-450 Enzyme Inhibitors Phase 4
18 Angiotensin II Type 1 Receptor Blockers Phase 4,Phase 3
19 Angiotensin Receptor Antagonists Phase 4,Phase 3
20 Angiotensin-Converting Enzyme Inhibitors Phase 4
21 Angiotensinogen Phase 4,Phase 3
22 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4,Phase 3,Phase 2
23 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
24 Hypolipidemic Agents Phase 4,Phase 3,Phase 2
25 Platelet Aggregation Inhibitors Phase 4,Phase 3
26 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
27 Immunosuppressive Agents Phase 4,Phase 3,Phase 1,Phase 2
28 Fibrinolytic Agents Phase 4,Phase 2
29 Anticholesteremic Agents Phase 4,Phase 3,Phase 2
30 Antifungal Agents Phase 4,Phase 3,Phase 1,Phase 2
31 Antihypertensive Agents Phase 4,Phase 3
32 Purinergic P2 Receptor Antagonists Phase 4
33 Purinergic P2Y Receptor Antagonists Phase 4
34 Lipid Regulating Agents Phase 4,Phase 3,Phase 2
35 Antimetabolites Phase 4,Phase 3,Phase 2
36 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 1,Phase 2
37 Calcium, Dietary Phase 4,Phase 2,Phase 3
38 Central Nervous System Depressants Phase 4,Phase 3
39 Analgesics Phase 4
40 diuretics Phase 4,Phase 1,Phase 2
41 Adjuvants, Anesthesia Phase 4
42 Narcotics Phase 4
43 Natriuretic Agents Phase 4,Phase 1,Phase 2
44 Cyclooxygenase Inhibitors Phase 4
45 Analgesics, Non-Narcotic Phase 4
46 Analgesics, Opioid Phase 4
47 Anesthetics Phase 4,Phase 3,Phase 1
48 Anesthetics, General Phase 4,Phase 3
49 Anesthetics, Intravenous Phase 4,Phase 3
50 Peripheral Nervous System Agents Phase 4,Phase 1,Phase 2

Interventional clinical trials:

(show top 50) (show all 135)
id Name Status NCT ID Phase
1 Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing Unknown status NCT00698607 Phase 4
2 Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD Unknown status NCT02008786 Phase 4
3 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4
4 Trial to Assess the Efficacy of Combination Formula of Aspirin Plus Clopidogrel in Patients With Coronary Stent Completed NCT02410083 Phase 4
5 Prevalence of Abdominal Aortic Aneurysm in Patients Undergoing Coronary Angiography Completed NCT01239225 Phase 4
6 Randomized Trial of Pulsatile vs Non Pulsatile Perfusion on Short Term Changes in Kidney Function Using an Intra-Aortic Ballooon Pump During Cardioplegic Arrest in Patients Undergoing Myocardial Reperfusion Completed NCT00454428 Phase 4
7 XIENCE V: SPIRIT WOMEN Sub-study Completed NCT01182428 Phase 4
8 The Pharmacokinetics of Opioids and Sedative/Hypnotics During Selective Cerebral Perfusion Completed NCT00494598 Phase 4
9 Add-on Effects of Valsartan on Morbi- Mortality (KYOTO HEART Study) Completed NCT00149227 Phase 4
10 MAPS Trial: Matrix And Platinum Science Completed NCT00396981 Phase 4
11 Eplerenone in the Management of Abdominal Aortic Aneurysms Recruiting NCT02345590 Phase 4
12 Clinical Evaluation of a Modular Extracorporeal Circulation Circuit Unknown status NCT02000544 Phase 3
13 Transradial Versus Transulnar Artery Approach for Coronary Interventions Unknown status NCT01364532 Phase 3
14 Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) Trial of Cardiovascular Events in High-Risk Hypertensive Patients Unknown status NCT00125463 Phase 3
15 Trial of Pulse Steroid Therapy in Kawasaki Disease--Pediatric Heart Network Completed NCT00132080 Phase 3
16 Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stents to Treat De Novo Coronary Lesions Completed NCT00301522 Phase 2, Phase 3
17 Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stent in the Treatment of In-Stent Restenosis Completed NCT00287573 Phase 2, Phase 3
18 SPIRIT FIRST Clinical Trial of the Abbott Vascular XIENCE V® Everolimus Eluting Coronary Stent System Completed NCT00180453 Phase 3
19 RADIAL Versus Femoral Access for Coronary Artery Bypass Graft Angiography and Intervention (RADIAL-CABG) Trial Completed NCT01446263 Phase 3
20 SPIRIT II: A Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System Completed NCT00180310 Phase 3
21 Angio-Seal® vs. Exo-Seal® for Closure of Arterial Puncture Sites Completed NCT01669382 Phase 3
22 ABSORB Clinical Investigation, Cohort A (ABSORB A) Everolimus Eluting Coronary Stent System Clinical Investigation Completed NCT00300131 Phase 3
23 SPIRIT III Clinical Trial of the XIENCE V® Everolimus Eluting Coronary Stent System (EECSS) Completed NCT00180479 Phase 3
24 VALOR: The Talent Thoracic Stent Graft System Clinical Study Completed NCT00604799 Phase 2, Phase 3
25 Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT) Completed NCT00064753 Phase 2, Phase 3
26 Esmolol Infusion in Patients Undergoing Craniotomy Completed NCT02455440 Phase 3
27 Simvastatin in Aneurysmal Subarachnoid Haemorrhage (STASH) a Multicentre Randomised Controlled Clinical Trial Completed NCT00731627 Phase 3
28 Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose Completed NCT01543555 Phase 3
29 KIDCARE (Kawasaki Disease Comparative Effectiveness Trial) Recruiting NCT03065244 Phase 3
30 Induced Hypertension for Treatment of Delayed Cerebral Ischaemia After Aneurysmal Subarachnoid Haemorrhage Terminated NCT01613235 Phase 3
31 Trial of Atorvastatin on the Persistent Coronary Aneurysm in Children With Kawasaki Disease Unknown status NCT02114099 Phase 2
32 Prevention of Coronary Aneurysms in Kawasaki Syndrome Completed NCT00000520 Phase 2
33 Pharmacokinetics of AP214 Acetate in Patients Undergoing Cardiac Surgery Completed NCT00903604 Phase 2
34 An Trial of Two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Surgery Completed NCT01256372 Phase 2
35 Safety Study of Dantrolene in Subarachnoid Hemorrhage Completed NCT01024972 Phase 1, Phase 2
36 The Transfusion Triggers in Vascular Surgery Trial Completed NCT02465125 Phase 2
37 Doxycycline Treatment to Prevent Progressive Coronary Artery Dilation in Children With Kawasaki Disease Recruiting NCT01917721 Phase 2
38 Anakinra and Kawasaki Disease Recruiting NCT02390596 Phase 2
39 Evaluation of Branch Endografts in the Treatment of Aortic Aneurysms Recruiting NCT01524211 Phase 2
40 Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage: Recruiting NCT02432157 Phase 1, Phase 2
41 ABSORB Clinical Investigation, Cohort B Active, not recruiting NCT00856856 Phase 1, Phase 2
42 Thrombolysis in Ischemic Spinal Cord Stroke Active, not recruiting NCT02242084 Phase 2
43 Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac Surgery Terminated NCT00628264 Phase 2
44 Study of Efficacy and Safety of Canakinumab in Pediatric Patients With Kawasaki Disease Withdrawn NCT02980263 Phase 2
45 A Web-Based Cardiovascular Intervention for the Workplace Unknown status NCT00763308 Phase 1
46 Preventing Myocardial Ischemia by Preconditioning in Elective Operation for Abdominal Aortic Aneurysm Unknown status NCT01523262 Phase 1
47 Clinical Study of Aneurysm Exclusion Unknown status NCT00549380 Phase 1
48 Goal Directed Therapy for Patients Undergoing Major Vascular Surgery Completed NCT01681251 Phase 1
49 Remote Ischemic Preconditioning in Subarachnoid Hemorrhage Completed NCT01158508 Phase 1
50 Intraoperative Nasal Insulin Effect on Plasma and CSF Insulin Concentration and Blood Glucose Recruiting NCT02729064 Phase 1

Search NIH Clinical Center for Coronary Artery Aneurysm

Genetic Tests for Coronary Artery Aneurysm

Anatomical Context for Coronary Artery Aneurysm

MalaCards organs/tissues related to Coronary Artery Aneurysm:

39
Heart, T Cells, Lymph Node, Endothelial, Prostate

Publications for Coronary Artery Aneurysm

Articles related to Coronary Artery Aneurysm:

(show top 50) (show all 559)
id Title Authors Year
1
Factors associated with development of coronary artery aneurysms after Kawasaki disease are similar for those treated promptly and those with delayed or no treatment. ( 28089146 )
2017
2
Complex coronary artery aneurysm. ( 27862313 )
2017
3
Coronary Artery Aneurysm After Bioresorbable Vascular Scaffold Implantation With Post-Dilation: Is Less More? ( 28017314 )
2017
4
Hybrid Management of a Giant Left Main Coronary Artery Aneurysm. ( 28007286 )
2017
5
Left Main Coronary Artery Aneurysm. ( 27403190 )
2016
6
Generation of a giant coronary artery aneurysm from an intra-plaque cavity with a ruptured fibrous cap: an observation over time through coronary angiography. ( 28078177 )
2016
7
Rapid Growth of Giant Coronary Artery Aneurysm Following Treatment of StentA Edge Dissection. ( 27318844 )
2016
8
Bilateral Giant Coronary Artery Aneurysms Complicated by Acute Coronary Syndrome and Cardiogenic Shock. ( 27000621 )
2016
9
Technical Considerations of Giant Right Coronary Artery Aneurysm Exclusion. ( 28018699 )
2016
10
Angiographic spontaneous pseudo-resolution of a coronary artery aneurysm after implantation of a sirolimus-eluting stent. ( 26813572 )
2016
11
Giant Coronary Artery Aneurysm Causing Acute Anterior Myocardial Infarction. ( 27891151 )
2016
12
Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease. ( 27171184 )
2016
13
Giant Right Coronary Artery Aneurysm Associated with a Fistula Draining into the Superior Vena Cava. ( 27547153 )
2016
14
Multiple Giant Coronary Artery Aneurysms: A Rare Cause of Sudden Cardiac Death. ( 27859306 )
2016
15
Multiple Coronary Artery Aneurysms and Thoracic Aortitis Associated with IgG4-related Disease. ( 27301513 )
2016
16
Left circumflex coronary artery aneurysm withA arteriovenous fistula to theA coronary sinus presenting as acute coronary syndrome. ( 27890910 )
2016
17
Acute coronary syndrome due to a giant right coronary artery aneurysm. ( 27773494 )
2016
18
Kawasaki Disease With Coronary Artery Aneurysms: Psychosocial Impact on Parents and Children. ( 28027841 )
2016
19
Successful management of a giant unruptured mycotic coronary artery aneurysm after coronary angioplasty. ( 27751325 )
2016
20
Coronary Artery Aneurysm After Everolimus-Eluting Bioabsorbable Vascular Scaffold Implantation. ( 26793967 )
2016
21
Coronary Artery Aneurysm and Coronary Artery Ectasia: What Makes the Difference? ( 27784732 )
2016
22
Cardiac Complications in 38 Cases of Kawasaki Disease with Coronary Artery Aneurysm Diagnosed by Echocardiography. ( 26711003 )
2016
23
Giant left anterior descending coronary artery aneurysm in an adult male patient with ST elevation myocardial infarction. ( 27021297 )
2016
24
Multiple Coronary Artery Aneurysms of the Right Coronary Artery in Neonate with Pulmonary Atresia with Intact Ventricular Septum. ( 26857432 )
2016
25
Giant Right Coronary Artery Aneurysm. ( 27333780 )
2016
26
Percutaneous exclusion of a rapidly enlarging left main coronary artery aneurysm using coils and an Amplatzera8c septal occluder. ( 26945542 )
2016
27
Bare Metal Stent for a Coronary Artery Aneurysm. ( 26831032 )
2016
28
Exclusion of a coronary artery aneurysm using the STENTYS Xposition S balloon-delivery system with optical coherence tomography guidance: precise positioning without trouble. ( 27649559 )
2016
29
How should I treat a patient with giant left main coronary artery aneurysm without associated stenosis? ( 26788711 )
2016
30
Acquired coronary artery aneurysm following treatment with bioresorbable vascular scaffolds. ( 27753602 )
2016
31
From Small Coronary Artery Aneurysm to Giant Left Ventricle Aneurysm. ( 27603926 )
2016
32
Role of gender in types and frequency of coronary artery aneurysm and ectasia. ( 27495054 )
2016
33
Coronary artery aneurysm after sequential stenting with bioresorbable vascular scaffolds. ( 27845999 )
2016
34
Coronary Artery Aneurysm Differs From Coronary Artery Ectasia: Angiographic Characteristics and Cardiovascular Risk Factor Analysis in Patients Referred for Coronary Angiography. ( 27568385 )
2016
35
Successful surgical treatment of a giant right coronary artery aneurysm with a patent left internal thoracic artery graft. ( 26984288 )
2016
36
Coronary Artery Aneurysms in Kawasaki Disease: Risk Factors for Progressive Disease and Adverse Cardiac Events in the US Population. ( 27633390 )
2016
37
Right Coronary Artery Aneurysm with Fistula to the Coronary Sinus, Persistent Left Superior Vena Cava, Ruptured Anterior Leaflet Chordae Tendineae with Severe Mitral Regurgitation. ( 26593222 )
2016
38
Giant Right Coronary Artery Aneurysm Mimicking a Mediastinal Cyst With Compression Effects: A Case Report. ( 27800453 )
2016
39
When Is a Coronary Artery Aneurysm Not an Aneurysm? ( 27106468 )
2016
40
Redo Operation of Recurrent Giant Coronary Artery Aneurysm: Optimizing Surgical Strategy. ( 28018827 )
2016
41
Embolic myocardial infarction due to coronary artery aneurysm in a patient with Loeys-Dietz syndrome. ( 27173863 )
2016
42
Galectin-3 and Kawasaki disease patients with special reference to coronary artery aneurysm. ( 26595790 )
2016
43
Development and receding of a coronary artery aneurysm after implantation of a fully bioresorbable scaffold. ( 25712060 )
2015
44
Giant Right Coronary Artery Aneurysm Masquerading as a Pulmonary Embolus. ( 26432082 )
2015
45
Measurements of Coronary Artery Aneurysms Due to Kawasaki Disease by Dual-Source Computed Tomography (DSCT). ( 26515298 )
2015
46
Giant right coronary artery aneurysm. ( 25648259 )
2015
47
Facial nerve palsy, Kawasaki disease, and coronary artery aneurysm. ( 26101056 )
2015
48
Genetic variants in PLCB4/PLCB1 as susceptibility loci for coronary artery aneurysm formation in Kawasaki disease in Han Chinese in Taiwan. ( 26434682 )
2015
49
Case Report: A Rare Case of a Giant Right Coronary Artery Aneurysm. ( 26306132 )
2015
50
Guideline-Concordant Treatment of Kawasaki Disease With Immunoglobulin and Aspirin and the Incidence of Coronary Artery Aneurysm. ( 25573948 )
2015

Variations for Coronary Artery Aneurysm

Expression for Coronary Artery Aneurysm

Search GEO for disease gene expression data for Coronary Artery Aneurysm.

Pathways for Coronary Artery Aneurysm

Pathways related to Coronary Artery Aneurysm according to GeneCards Suite gene sharing:

(show all 27)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.83 CCL17 CCL2 ITPR3 MMP1 MMP12 MMP13
2
Show member pathways
12.45 MMP1 MMP12 MMP13 MMP3 MMP7 VCAM1
3
Show member pathways
12.09 CCL2 MMP1 MMP13 MMP3
4
Show member pathways
11.99 CCL17 CCL2 MMP1 MMP13 MMP3
5 11.85 ITPR3 PLCB1 PLCB4
6 11.84 ITPR3 PLCB1 PLCB4
7 11.83 KLK3 MMP3 VCAM1
8 11.81 CCL2 MMP3 VCAM1
9 11.77 ITPR3 PLCB1 PLCB4
10 11.76 CCL2 MMP1 MMP3 VCAM1
11 11.73 ADIPOQ LEP VCAM1
12 11.73 ITPR3 PLCB1 PLCB4
13 11.69 CCL2 MMP1 MMP3
14 11.66 CCL2 MMP3 MMP7
15 11.66 CCL2 PLCB1 PLCB4 VCAM1
16
Show member pathways
11.55 MMP1 MMP12 MMP13 MMP3 MMP7
17 11.51 ITPR3 PLCB1 PLCB4
18
Show member pathways
11.49 MMP1 MMP3 VCAM1
19 11.45 ITPR3 PLCB1 PLCB4
20 11.24 MMP13 PLCB1 PLCB4
21 11.18 PLCB1 PLCB4 VCAM1
22 11.17 ITPR3 PLCB1 PLCB4
23 11.15 ITPR3 PLCB1 PLCB4
24 10.91 CCL2 MMP1
25 10.89 KLK3 MMP1 MMP12 MMP13 MMP3 MMP7
26 10.83 MMP1 MMP7
27 10.8 CCL2 VCAM1

GO Terms for Coronary Artery Aneurysm

Cellular components related to Coronary Artery Aneurysm according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 ADIPOQ CCL17 CCL2 KLK3 LEP MMP1
2 proteinaceous extracellular matrix GO:0005578 9.65 MMP1 MMP12 MMP13 MMP3 MMP7
3 extracellular matrix GO:0031012 9.55 MMP1 MMP12 MMP13 MMP3 MMP7
4 extracellular space GO:0005615 9.36 ADIPOQ CCL17 CCL2 KLK3 LEP MMP12

Biological processes related to Coronary Artery Aneurysm according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.93 KLK3 MMP1 MMP12 MMP13 MMP3 MMP7
2 cellular response to tumor necrosis factor GO:0071356 9.72 CCL17 CCL2 VCAM1
3 aging GO:0007568 9.71 CCL2 MMP7 RETN VCAM1
4 response to nutrient GO:0007584 9.67 ADIPOQ LEP VCAM1
5 response to hypoxia GO:0001666 9.67 ADIPOQ CCL2 LEP VCAM1
6 response to nutrient levels GO:0031667 9.61 ADIPOQ LEP MMP7
7 positive regulation of synaptic transmission GO:0050806 9.54 CCL2 RETN
8 leukocyte tethering or rolling GO:0050901 9.52 LEP VCAM1
9 positive regulation of protein oligomerization GO:0032461 9.51 MMP1 MMP3
10 chronic inflammatory response GO:0002544 9.48 CCL2 VCAM1
11 response to ethanol GO:0045471 9.46 ADIPOQ CCL2 LEP VCAM1
12 response to activity GO:0014823 9.43 ADIPOQ CCL2 LEP
13 extracellular matrix disassembly GO:0022617 9.35 MMP1 MMP12 MMP13 MMP3 MMP7
14 positive regulation of developmental growth GO:0048639 9.32 LEP PLCB1
15 collagen catabolic process GO:0030574 9.02 MMP1 MMP12 MMP13 MMP3 MMP7

Molecular functions related to Coronary Artery Aneurysm according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 9.88 KLK3 MMP1 MMP12 MMP13 MMP3 MMP7
2 calcium ion binding GO:0005509 9.87 ITPR3 MMP1 MMP12 MMP13 MMP3 PLCB1
3 receptor binding GO:0005102 9.83 ADIPOQ BAG6 CCL17 CCL2 LEP
4 hormone activity GO:0005179 9.63 ADIPOQ LEP RETN
5 endopeptidase activity GO:0004175 9.56 KLK3 MMP1 MMP12 MMP3
6 metallopeptidase activity GO:0008237 9.55 MMP1 MMP12 MMP13 MMP3 MMP7
7 serine-type endopeptidase activity GO:0004252 9.43 KLK3 MMP1 MMP12 MMP13 MMP3 MMP7
8 metalloendopeptidase activity GO:0004222 9.02 MMP1 MMP12 MMP13 MMP3 MMP7
9 hydrolase activity GO:0016787 10.02 ABHD16A KLK3 MMP1 MMP12 MMP13 MMP3

Sources for Coronary Artery Aneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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