MCID: CRN074
MIFTS: 40

Coronary Artery Aneurysm malady

Rare diseases, Cardiovascular diseases, Fetal diseases categories
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Summaries for Coronary Artery Aneurysm

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Sources:
65Wikipedia, 33MalaCards
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Wikipedia:65 Coronary artery aneurysm is an abnormal dilatation of part of the coronary artery. more...

MalaCards: Coronary Artery Aneurysm is related to coronary artery disease and abdominal aortic aneurysm. An important gene associated with Coronary Artery Aneurysm is MMP12 (matrix metallopeptidase 12 (macrophage elastase)), and among its related pathways are Colorectal Cancer Metastasis and Protein Stability. The compounds carbamazepine and hydroxamate have been mentioned in the context of this disorder. Affiliated tissues include heart, lymph node and t cells.

Aliases & Classifications for Coronary Artery Aneurysm

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Sources:
43NIH Rare Diseases, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Fetal diseases
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

coronary artery aneurysm 43


External Ids:

ICD1025 I25.4

Related Diseases for Coronary Artery Aneurysm

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Sources:
17GeneCards, 18GeneDecks
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Diseases in the Coronary Artery Aneurysm family:

Congenital Coronary Artery Aneurysm

Diseases related to Coronary Artery Aneurysm via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 69)
idRelated DiseaseScoreTop Affiliating Genes
1coronary artery disease30.4MMP13, MMP7, MMP12
2abdominal aortic aneurysm30.3MMP12, MMP13
3arthritis30.3MMP12, MMP13
4rheumatoid arthritis30.2MMP12, MMP13
5aneurysm11.5
6kawasaki disease11.1
7myocardial infarction10.9
8acute myocardial infarction10.7
9arteriovenous fistula10.6
10cardiac tamponade10.5
11coronary arterial fistulas10.5
12congenital coronary artery aneurysm10.5
13mediastinitis10.5
14neurofibromatosis10.4
15endocarditis10.4
16takayasu's arteritis10.3
17cerebritis10.3
18systemic lupus erythematosus10.3
19patent ductus arteriosus10.3
20marfan syndrome10.3
21aortic aneurysm10.3
22artery disease10.3
23atherosclerosis10.3
24infective endocarditis10.3
25lupus erythematosus10.3
26aneurysm of sinus of valsalva10.3
27crohn's disease10.2
28supravalvular aortic stenosis10.2
29wolff-parkinson-white syndrome10.2
30pyuria10.2
31mitral valve prolapse10.2
32polyarteritis nodosa10.2
33tetralogy of fallot10.2
34cocaine abuse10.2
35hemopericardium10.2
36coronary aneurysm10.2
37mixed connective tissue disease10.2
38wegener's granulomatosis10.2
39osteogenesis imperfecta10.2
40behcet's disease10.2
41congestive heart failure10.2
42connective tissue disease10.2
43neutropenia10.2
44obesity10.2
45pneumonia10.2
46prostatitis10.2
47sarcoidosis10.2
48chronic active epstein-barr virus infection10.2
49gigantism10.2
50granulomatosis with polyangiitis10.2

Graphical network of the top 20 diseases related to Coronary Artery Aneurysm:



Diseases related to coronary artery aneurysm

Symptoms for Coronary Artery Aneurysm

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Drugs & Therapeutics for Coronary Artery Aneurysm

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Coronary Artery Aneurysm

Search NIH Clinical Center for Coronary Artery Aneurysm

Genetic Tests for Coronary Artery Aneurysm

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Anatomical Context for Coronary Artery Aneurysm

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33MalaCards
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MalaCards organs/tissues related to Coronary Artery Aneurysm:

33
Heart, Lymph node, T cells, Prostate, Endothelial

Animal Models for Coronary Artery Aneurysm or affiliated genes

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Publications for Coronary Artery Aneurysm

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52PubMed
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Articles related to Coronary Artery Aneurysm:

(show top 50)    (show all 455)
idTitleAuthorsYear
1
Atorvastatin safety in kawasaki disease patients with coronary artery aneurysms. (23864222)
2014
2
Giant coronary artery aneurysm. (23230818)
2013
3
Giant right coronary artery aneurysm with a huge intramural thrombus. (23523033)
2013
4
Prolidase Activity in Patients With Coronary Artery Aneurysm. (23748981)
2013
5
Giant aneurysm of the Valsalva sinus associated with multiple coronary artery aneurysms and patent ductus arteriosus. (24092249)
2013
6
Coronary artery aneurysm after implantation of an endothelial progenitor cell capturing stent. (22718389)
2012
7
Rapidly progressing coronary artery aneurysm and left ventricular diverticulum. (22870753)
2012
8
Unusual case of acute myocardial infarct: thrombosis of a large coronary artery aneurysm. (22913245)
2012
9
A rare case of giant coronary artery aneurysm in the context of multiple arterial aneurysms. (22543232)
2012
10
Image-based modeling of hemodynamics in coronary artery aneurysms caused by Kawasaki disease. (22120599)
2012
11
A giant right coronary artery aneurysm as an incidental finding. (21421587)
2011
12
Giant coronary artery aneurysm with coronary arteriovenous fistula draining into the coronary sinus. (21678126)
2011
13
Coronary artery aneurysm and thrombosis following chronic ephedra use. (18718687)
2010
14
Ring-calcification of giant coronary artery aneurysm of an 11-year-old child with history of kawasaki disease. (19936583)
2010
15
Resection and patch repair of a large saccular coronary artery aneurysm at the left main bifurcation. (19101318)
2009
16
Usefulness of 64-slice MDCT for follow-up of young children with coronary artery aneurysm due to Kawasaki disease: initial experience. (18164157)
2009
17
Surgical treatment of giant coronary artery aneurysm secondary to Kawasaki disease. (19683998)
2009
18
Giant coronary artery aneurysm in Behets disease. (21687193)
2009
19
Evaluation of small coronary artery aneurysm by 64-slice multi-detector CT coronary angiography and virtual angioscopy. (18849214)
2008
20
Resection of a right coronary artery aneurysm with fistula to the coronary sinus. (18222289)
2008
21
Giant left anterior descending coronary artery aneurysm. (17395300)
2008
22
A case of recurrent myocardial infarction caused by a giant right coronary artery aneurysm. (17681729)
2007
23
Giant coronary artery aneurysm formation following meningococcal septicaemia. (17486388)
2007
24
Drug-eluting stent-induced left anterior descending coronary artery aneurysm: repair by pericardial patch--where are we headed? (17383377)
2007
25
A giant coronary artery aneurysm in the right coronary artery. (16697928)
2006
26
Surgical treatment of giant coronary artery aneurysm. (16153934)
2005
27
A young man with myocardial infarction and a calcified coronary artery aneurysm on chest radiography. (15605671)
2004
28
Surgical management of a giant left main coronary artery aneurysm. (15514604)
2004
29
Successful surgical repair of a giant left main coronary artery aneurysm with arteriovenous fistula draining into a persistent left superior vena cava and coronary sinus: role of intraoperative transesophageal echocardiography. (14652614)
2003
30
Detection of saccular coronary artery aneurysm associated with coronary-pulmonary artery fistula using Tc-99m HSAD scintigraphy. (12592131)
2003
31
ICUS-guided obliteration of a complex coronary artery aneurysm with a PTFE-covered stent. (12890878)
2003
32
Congenital right coronary artery aneurysm causing myocardial infarction, pseudoaneurysm formation, and right atrial compression. (12094173)
2002
33
Coronary artery aneurysm and type-A aortic dissection demonstrated by retrospectively ECG-gated multislice spiral CT. (11868099)
2002
34
Management of a single coronary artery aneurysm by use of a stent. (16333446)
2002
35
Giant coronary artery aneurysm arising from sinus node artery. (11603468)
2001
36
Thrombosed giant coronary artery aneurysm presenting as an intracardiac mass. (10735709)
2000
37
Coronary artery aneurysm after stent implantation. (10481393)
1999
38
Surgical treatment of a coronary artery fistula with concomitant saccular coronary artery aneurysm: a case report. (10553926)
1999
39
Solitary focal coronary artery aneurysm in a middle aged male with atypical chest pain. (10972014)
1999
40
Intravascular ultrasonography of an adolescent boy with a coronary artery aneurysm due to Kawasaki disease. (9326692)
1997
41
Coronary artery aneurysm in two patients with long-standing Lyme borreliosis. Borreliosis Study Group. (7968011)
1994
42
Coronary artery aneurysm formation following directional coronary atherectomy. (1446330)
1992
43
Sudden death in a young adult due to coronary artery aneurysm secondary to suspected Kawasaki disease. (1469919)
1992
44
Giant coronary artery aneurysm: detection with echocardiography, computed tomography, and magnetic resonance imaging. (2017988)
1991
45
Coronary artery aneurysm formation following PTCA. (2954647)
1987
46
Atherosclerotic coronary artery aneurysm progressing to coronary artery fistula: presentation as myocardial infarction with continuous murmur. (3604901)
1987
47
Prediction of patients with a high risk of coronary artery aneurysm in Kawasaki disease: indication for immunoglobulin therapy. (3423043)
1987
48
Ruptured coronary artery aneurysm--a rare cause of hemopericardium. (2413581)
1985
49
Huge left coronary artery aneurysm associated with multiple arterial aneurysms. (4075337)
1985
50
Mucocutaneous lymph node syndrome with coronary artery aneurysm. (7133)
1976

Variations for Coronary Artery Aneurysm

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Expression for genes affiliated with Coronary Artery Aneurysm

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Coronary Artery Aneurysm

Search GEO for disease gene expression data for Coronary Artery Aneurysm.

Pathways for genes affiliated with Coronary Artery Aneurysm

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Sources:
50PathCards, 53QIAGEN, 5Cell Signaling Technology, 55Reactome, 38NCBI BioSystems Database, 60Thomson Reuters, 12EMD Millipore
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Compounds for genes affiliated with Coronary Artery Aneurysm

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Sources:
45Novoseek, 51PharmGKB, 11DrugBank, 61Tocris Bioscience, 24HMDB
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Compounds related to Coronary Artery Aneurysm according to GeneCards/GeneDecks:

(show all 19)
idCompoundScoreTop Affiliating Genes
1carbamazepine45 51 1111.6PRRC2A, BAG6
2hydroxamate459.5MMP12, MMP13
3(4-aminophenyl)mercuric acetate459.4MMP7, MMP13
4p002459.2MMP13, MMP7
5gm 6001619.1MMP12, MMP13, MMP7
6uk 383367619.0MMP13, MMP7, MMP12
7gi 254023x619.0MMP13, MMP7, MMP12
8marimastat45 61 1111.0MMP12, MMP7, MMP13
9batimastat45 61 1111.0MMP13, MMP7, MMP12
10matrigel459.0MMP12, MMP7, MMP13
11fibrinogen459.0MMP13, MMP7, MMP12
12oligonucleotide458.9MMP12, MMP7, MMP13
13vegf458.9MMP12, MMP7, MMP13
14phosphatidylinositol458.9MMP13, MMP7, MMP12
15zinc45 249.8MMP12, MMP7, MMP13
16egcg458.8MMP7, MMP13
17nitric oxide45 24 1110.7MMP12, MMP7, MMP13
18oxygen45 249.7MMP12, MMP7, MMP13
19calcium45 51 24 1111.1MMP13, MMP7, MMP12, ITPKC

GO Terms for genes affiliated with Coronary Artery Aneurysm

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16Gene Ontology
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Cellular components related to Coronary Artery Aneurysm according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1proteinaceous extracellular matrixGO:0055788.7MMP12, MMP7, MMP13

Biological processes related to Coronary Artery Aneurysm according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of cell proliferationGO:0421279.3BAG6, MMP7
2collagen catabolic processGO:0305748.8MMP12, MMP7, MMP13
3extracellular matrix disassemblyGO:0226178.7MMP12, MMP7, MMP13
4proteolysisGO:0065088.6MMP13, MMP7, MMP12
5extracellular matrix organizationGO:0301988.4MMP12, MMP7, MMP13

Molecular functions related to Coronary Artery Aneurysm according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1metalloendopeptidase activityGO:0042228.7MMP12, MMP7, MMP13

Products for genes affiliated with Coronary Artery Aneurysm

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Coronary Artery Aneurysm

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet