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MCID: CRN018
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Coronary Artery Anomaly malady |
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Sources: 23MedlinePlus, 17Genetics Home Reference, 44Wikipedia, 22MalaCards See all sources Export this MalaCard |
MedlinePlus: Coronary artery disease (cad) is the most common type of heart disease. it is the leading cause of death in the united states in both men and women.
cad happens when the arteries that supply blood to heart muscle become hardened and narrowed. this is due to the buildup of cholesterol and other material, called plaque, on their inner walls. this buildup is called atherosclerosis. as it grows, less blood can flow through the arteries. as a result, the heart muscle can't get the blood or oxygen it needs. this can lead to chest pain (angina) or a heart attack. most heart attacks happen when a blood clot suddenly cuts off the hearts' blood supply, causing permanent heart damage.
over time, cad can also weaken the heart muscle and contribute to heart failure and arrhythmias. heart failure means the heart can't pump blood well to the rest of the body. arrhythmias are changes in the normal beating rhythm of the heart.
nih: national heart, lung, and blood institute23
MalaCards: Coronary Artery Anomaly, also known as coronary artery disease, is related to myocardial infarction and insulin resistance. An important gene associated with Coronary Artery Anomaly is KDR (kinase insert domain receptor (a type III receptor tyrosine kinase)), and among its related pathways are Development_VEGF signaling and activation and Development VEGF signaling and activation. The compounds hcec and cocl2 have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and skin, and related mouse phenotype embryogenesis. Genetics Home Reference: Werner syndrome is characterized by the dramatic, rapid appearance of features associated with normal aging. Individuals with this disorder typically grow and develop normally until they reach puberty. Affected teenagers usually do not have a growth spurt, resulting in short stature. The characteristic aged appearance of individuals with Werner syndrome typically begins to develop when they are in their twenties and includes graying and loss of hair; a hoarse voice; and thin, hardened skin. They may also have a facial appearance described as "bird-like." Many people with Werner syndrome have thin arms and legs and a thick trunk due to abnormal fat deposition.17 Wikipedia: Coronary artery anomalies (or malformation of coronary vessels) are congenital abnormalities in the...44 more... |
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Sources: 6Disease Ontology, 7diseasecard, 33OMIM, 32Novoseek , 23MedlinePlus, 43UMLS, 19ICD9CM, 40SNOMED-CT See all sources |
Aliases & Descriptions:
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Sources: 4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT See all sources |
Approved drugs:Search CenterWatch for coronary artery anomaly Drug clinical trials:Search ClinicalTrials for coronary artery anomaly Search NIH Clinical Center for coronary artery anomaly Search CenterWatch for coronary artery anomaly |
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Sources: 22MalaCards See all sources |
MalaCards organs/tissues related to coronary artery anomaly:22Heart, Lung, Skin
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Sources: 25MGI See all sources |
MGI Mouse Phenotypes related to coronary artery anomaly:25
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Sources: 35PubMed See all sources |
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Sources: 1BioGPS See all sources |
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Sources: 41Thomson Reuters, 10EMD Millipore See all sources |
Pathways related to coronary artery anomaly according to GeneDecks:
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Sources: 32Novoseek , 34PharmGKB, 42Tocris Bioscience, 9DrugBank, 18HMDB See all sources |
Compounds related to coronary artery anomaly according to GeneDecks:(show all 26)
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Sources: 12Gene Ontology See all sources |
Cellular components related to coronary artery anomaly according to GeneDecks:
Biological processes related to coronary artery anomaly according to GeneDecks:
Molecular functions related to coronary artery anomaly according to GeneDecks:
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