MCID: CRN211
MIFTS: 77

Coronary Artery Disease malady

Genetic diseases (common) category

Summaries for Coronary Artery Disease

About this section


MedlinePlus:34 Coronary artery disease (cad) is the most common type of heart disease. it is the leading cause of death in the united states in both men and women. cad happens when the arteries that supply blood to heart muscle become hardened and narrowed. this is due to the buildup of cholesterol and other material, called plaque, on their inner walls. this buildup is called atherosclerosis. as it grows, less blood can flow through the arteries. as a result, the heart muscle can't get the blood or oxygen it needs. this can lead to chest pain (angina) or a heart attack. most heart attacks happen when a blood clot suddenly cuts off the hearts' blood supply, causing permanent heart damage. over time, cad can also weaken the heart muscle and contribute to heart failure and arrhythmias. heart failure means the heart can't pump blood well to the rest of the body. arrhythmias are changes in the normal beating rhythm of the heart. nih: national heart, lung, and blood institute

MalaCards based summary: Coronary Artery Disease, also known as coronary heart disease, is related to myocardial infarction and atherosclerosis. An important gene associated with Coronary Artery Disease is CX3CR1 (chemokine (C-X3-C motif) receptor 1), and among its related pathways are Cholesterol and Sphingolipids transport Recycling to plasma membrane in lung normal and CF and COPI Mediated Transport. The compounds sele and fenofibric acid have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and monocytes, and related mouse phenotypes are normal and liver/biliary system.

Disease Ontology:10 An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.

Wikipedia:65 Coronary artery disease (CAD), also known as ischemic heart disease (IHD),atherosclerotic heart... more...

Description from OMIM:47 607339

Aliases & Classifications for Coronary Artery Disease

About this section

Coronary Artery Disease, Aliases & Descriptions:

Name: Coronary Artery Disease 47 32 10 11 45 34
Coronary Heart Disease 10 12 45
Coronary Heart Disease 1 47 24
Coronary Artery Anomaly 32 10
Myocardial Ischemia 10 45
Chd 10 39
Coronary Artery Disease, Susceptibility to 11
Coronary Heart Disease, Susceptibility to 11
 
Congenital Anomaly of Coronary Artery 10
Coronary Artery Anomaly, Congenital 10
Chronic Myocardial Ischaemia 10
Coronary Artery Abnormality 10
Coronary Artery Anomaly Nos 10
Coronary Arteriosclerosis 10
Ischemic Heart Disease 10
Coronary Disease 10


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Related Diseases for Coronary Artery Disease

About this section

Diseases in the Coronary Artery Disease family:

Coronary Artery Disease, Autosomal Dominant, 1 Coronary Artery Disease, Autosomal Dominant, 2

Diseases related to Coronary Artery Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 382)
idRelated DiseaseScoreTop Affiliating Genes
1myocardial infarction31.6P2RY12, PON1, APOB, APOA5, APOC3, APOA1
2atherosclerosis31.4CCL2, MEF2A, CETP, CX3CR1, P2RY12, PON1
3acute myocardial infarction31.1ACE, PON1, APOB, APOA1
4coronary stenosis31.0APOA1, APOB, PON1, CETP
5peripheral vascular disease31.0APOA1, APOB, CETP, ACE
6obesity30.9ABCA1, APOA1, APOC3, APOA5, APOB, PON1
7vascular disease30.9HP
8arteriosclerosis30.7CCL2, PON1, APOB, APOA1
9kidney disease30.7APOA1, APOB, CCL2, HP
10hypertriglyceridemia30.7APOB, APOC3
11fatty liver disease30.7HP, CETP, APOB, APOC3, APOA1
12hypoalphalipoproteinemia30.6ABCA1, APOA1, APOC3, APOB, CETP
13cerebrovascular disease30.6APOA1, ACE, CETP, CX3CR1, PON1, APOB
14alzheimer disease30.6MEF2A, CETP, PON1, APOB, APOC3, ABCA1
15carotid artery disease30.5PON1, APOB
16hyperglycemia30.5APOB, PON1, CETP, ACE
17tangier disease30.5ABCA1, APOA1, APOC3, APOB, CETP
18arcus senilis30.4APOB, APOA1
19xanthomatosis30.4APOB, ABCA1
20congenital heart disease30.4CCL2, ACE, HP
21systemic scleroderma30.4ACE, CCL2, CX3CR1
22hyperinsulinism30.4CETP, APOB, APOA1
23abdominal aortic aneurysm30.3CCL2, CETP
24cerebral atherosclerosis30.2APOA1
25hyperlipidemia, familial combined30.2APOB, APOA1
26hypercholesterolemia, familial30.2APOB, CETP
27hypothyroidism30.2APOB, PON1, CETP
28abetalipoproteinemia30.1CETP, APOB, APOA1
29hyperlipidemia type 330.1APOA1, APOA5, APOB, CETP
30glucose intolerance30.1APOA1, APOB, PON1, CETP
31metabolic syndrome x30.1ABCA1, APOA1, APOB, CETP
32hyperalphalipoproteinemia30.1ABCA1, APOA1, APOC3, APOB, CETP
33familial hyperlipidemia30.1APOA1, APOC3, APOA5, APOB, CETP
34nephrotic syndrome30.1APOA1, APOB, PON1, CETP, ACE, HP
35proteinuria30.1APOA1, APOC3, APOB, CETP, CCL2, ACE
36asthma30.1CCL2, CETP, CX3CR1, PON1
37lipid metabolism disorder30.1ABCA1, APOA1, ACE, CCL2, CETP, PON1
38rheumatoid arthritis30.1TERT, APOA1, PON1, CX3CR1, CCL2, HP
39artery disease11.8
40endotheliitis11.1
41chronic myocardial ischemia10.8
42ischemia10.8
43angina pectoris10.8
44hepatitis10.7
45blindness10.6
46hyperhomocysteinemia10.6
47aneurysm10.6
48aortic atherosclerosis10.5
49peripheral artery disease10.5
50periodontitis10.5

Graphical network of the top 20 diseases related to Coronary Artery Disease:



Diseases related to coronary artery disease

Symptoms for Coronary Artery Disease

About this section


Clinical features from OMIM:

607339

Drugs & Therapeutics for Coronary Artery Disease

About this section

Drug clinical trials:

Search ClinicalTrials for Coronary Artery Disease

Search NIH Clinical Center for Coronary Artery Disease

Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Read about Coronary Artery Disease cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Coronary Artery Disease:
Enriched bone marrow-derived progenitor cells for heart diseases
Embryonic/Adult Cultured Cells Related to Coronary Artery Disease:
Bone marrow-derived progenitor cells, PMIDs: 23362308, 22936827, 18794392, 16990384, 16990385, 22651868

Genetic Tests for Coronary Artery Disease

About this section

Genetic tests related to Coronary Artery Disease:

id Genetic test Affiliating Genes
1 Coronary Heart Disease 124

Anatomical Context for Coronary Artery Disease

About this section

MalaCards organs/tissues related to Coronary Artery Disease:

33
Heart, Endothelial, Monocytes, Lung, Testes, Bone, Kidney, Brain, Liver, Neutrophil, Adipocyte, Smooth muscle, T cells, Pons, Whole blood, Thyroid, Ovary, Prostate, Eye, Skeletal muscle, Colon, Breast, Skin, B cells, Pituitary

Animal Models for Coronary Artery Disease or affiliated genes

About this section

Publications for Coronary Artery Disease

About this section

Articles related to Coronary Artery Disease:

(show top 50)    (show all 2919)
idTitleAuthorsYear
1
Bifurcation stenting techniques and outcomes in patients with stable coronary artery disease: more evidence suggesting simpler is safer. (25907083)
2015
2
Comparison of Cardiorespiratory Responses During Aquatic and Land Treadmill Exercise in Patients With Coronary Artery Disease. (25407597)
2014
3
Association of natriuretic peptide polymorphisms with left ventricular dysfunction in southern Han Chinese coronary artery disease patients. (25400811)
2014
4
P2Y12 receptor gene polymorphism and antiplatelet effect of clopidogrel in patients with coronary artery disease after coronary stenting. (23751603)
2013
5
Association of PON1 genotype and haplotype with susceptibility to coronary artery disease and clinical outcomes in dual antiplatelet-treated Han Chinese patients. (23608957)
2013
6
C-reactive protein, fatal and nonfatal coronary artery disease, stroke, and peripheral artery disease in the prospective EPIC-Norfolk cohort study. (24072695)
2013
7
Relationship between cytochrome P450 2C19*17 genotype distribution, platelet aggregation and bleeding risk in patients with blood stasis syndrome of coronary artery disease treated with clopidogrel. (22704413)
2012
8
Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease. (21701070)
2011
9
Association of serum TRAIL level with coronary artery disease. (20034655)
2010
10
Associations between common polymorphisms of adenosine triphosphate-binding cassette transporter A1 and coronary artery disease in a Tunisian population. (21130966)
2010
11
Fasting serum level of fatty-acid-binding protein 4 positively correlates with metabolic syndrome in patients with coronary artery disease. (20009357)
2010
12
Human platelet alloantigens HPA-1, HPA-2, and HPA-3 polymorphisms associated with extent of severe coronary artery disease. (19562259)
2010
13
Endostatin and angiostatin are increased in diabetic patients with coronary artery disease and associated with impaired coronary collateral formation. (19074676)
2009
14
Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease. (19429918)
2009
15
Interleukin-3 is elevated in patients with coronary artery disease and predicts restenosis after percutaneous coronary intervention. (18378332)
2009
16
Insulin response to oral glucose load is associated with coronary artery disease in subjects with normal glucose tolerance. (18270458)
2008
17
Human paraoxonase gene polymorphisms and coronary artery disease risk. (19280995)
2008
18
Five-year follow-up of drug utilization for secondary prevention in coronary artery disease. (18563622)
2008
19
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. (18193043)
2008
20
The 677 C/T MTHFR polymorphism is associated with essential hypertension, coronary artery disease, and higher homocysteine levels. (18068006)
2008
21
Myeloperoxidase level in patients with stable coronary artery disease and acute coronary syndromes. (18226042)
2008
22
Homocysteinemia as an independent risk factor in the Chinese population at a high risk of coronary artery disease. (17659928)
2007
23
Factors influencing thrombin generation measured as thrombin-antithrombin complexes levels and using calibrated automated thrombogram in patients with advanced coronary artery disease]. (17966595)
2007
24
The value of percutaneous coronary intervention in aortic valve stenosis with coronary artery disease. (17275462)
2007
25
Association of the MspI polymorphism of cytochrome P4501A1 gene and smoking to the susceptibility to coronary artery disease]. (17711714)
2007
26
DNA repair gene XRCC1 and XPD polymorphisms and their association with coronary artery disease risks and micronucleus frequency. (18043991)
2007
27
Tag polymorphisms at the A20 (TNFAIP3) locus are associated with lower gene expression and increased risk of coronary artery disease in type 2 diabetes. (17259397)
2007
28
Angiotensin-I-converting enzyme (ACE) insertion/deletion polymorphism in Mexican patients with coronary artery disease. Association with the disease but not with lipid levels. (16764852)
2006
29
The CAREGENE study: ACE gene I/D polymorphism and effect of physical training on aerobic power in coronary artery disease. (16085717)
2006
30
ACE inhibition in stable coronary artery disease. (15751129)
2005
31
High serum interleukin-18 concentrations in patients with coronary artery disease and type 2 diabetes mellitus. (16266856)
2005
32
Usefulness of high-sensitivity IL-6 measurement for clinical characterization of patients with coronary artery disease. (15900566)
2005
33
Association of plasma cholesteryl ester transfer protein activity and polymorphism with coronary artery disease extent in Tunisian type II diabetic patients. (15766738)
2005
34
Association of oestrogen receptor alpha gene polymorphism with the angiographic extent of coronary artery disease. (14972425)
2004
35
Role of angiogenic growth factors in transplant coronary artery disease. (15181974)
2004
36
Effects of statins on coronary artery disease. Review of the recent publications]. (12884643)
2003
37
Molecular analysis of the estrogen receptor alpha gene in men with coronary artery disease: association with disease status. (12691862)
2003
38
Association between the severity of angiographic coronary artery disease and paraoxonase gene polymorphisms in the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) study. (12454802)
2003
39
Enhanced bridging function and augmented monocyte adhesion by lipoprotein lipase N9: insights into increased risk of coronary artery disease in N9 carriers. (12535736)
2003
40
Relation of markers of inflammation (C-reactive protein, fibrinogen, von Willebrand factor, and leukocyte count) and statin therapy to long-term mortality in patients with angiographically proven coronary artery disease. (11950425)
2002
41
Coronary artery disease in systemic lupus erythematosus: A review of the literature. (11404827)
2001
42
Soluble adhesion molecules and unstable coronary artery disease. (11395039)
2001
43
Lack of evidence for association between endothelial nitric oxide synthase gene polymorphisms and coronary artery disease in the Australian Caucasian population. (11551002)
2001
44
Effects of fluvastatin and bezafibrate combination on plasma fibrinogen, t-plasminogen activator inhibitor and C reactive protein levels in coronary artery disease patients with mixed hyperlipidaemia (FACT Study)--a rebuttal. (11204580)
2001
45
Relevance of apolipoprotein E polymorphism for coronary artery disease in the Saudi population. (10583930)
1999
46
The prothrombin 20210A allele and the factor V Leiden are associated with venous thrombosis but not with early coronary artery disease. (10070834)
1999
47
Mechanism by which quinapril improves vascular function in coronary artery disease. (10072217)
1999
48
Recombinant hirudin in patients with chronic, stable coronary artery disease. Safety, half-life, and effect on coagulation parameters. (8222093)
1993
49
Familial hypoalphalipoproteinemia in premature coronary artery disease. (8241092)
1993
50
Fibrinolytic activity in coronary artery disease and myocardial infarction, and the role of fibrinolytic therapy in coronary thrombosis. (5648576)
1968

Variations for Coronary Artery Disease

About this section

Expression for genes affiliated with Coronary Artery Disease

About this section

Search GEO for disease gene expression data for Coronary Artery Disease.

Pathways for genes affiliated with Coronary Artery Disease

About this section

Pathways related to Coronary Artery Disease according to GeneCards/GeneDecks:

(show all 14)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2APOA1, ABCA1
2
Show member pathways
10.2CETP, ABCA1
310.2APOB, APOA1
410.1ACE, CCL2, CX3CR1
5
Show member pathways
fatty acid beta-oxidation VI (peroxisome)38
10.1APOA1, APOC3, APOA5
6
Show member pathways
10.1HP, APOB, APOA1
7
Show member pathways
10.1APOB, APOA1, ABCA1
810.1ABCA1, APOA1, APOB
9
Show member pathways
10.0APOB, APOC3, APOA1
10
Show member pathways
thioredoxin pathway38
9.9ABCA1, APOA1, APOB, CCL2
11
Show member pathways
9.7ABCA1, APOA1, APOC3, APOA5, APOB, CETP
12
Show member pathways
9.6ABCA1, APOA1, APOC3, APOA5, APOB, PON1
13
Show member pathways
9.6CETP, ABCA1, APOA1, APOC3, APOA5, APOC4
14
Show member pathways
9.4APOA1, APOC3, APOB, P2RY12, CX3CR1, MEF2A

Compounds for genes affiliated with Coronary Artery Disease

About this section

Compounds related to Coronary Artery Disease according to GeneCards/GeneDecks:

(show top 50)    (show all 129)
idCompoundScoreTop Affiliating Genes
1sele4510.3PON1, ACE, APOC3, CETP
2fenofibric acid45 3011.3CCL2, APOB, APOC3, APOA1
3intralipid4510.3APOC3, APOB, CETP, APOA1
4ezetimibe45 1311.3APOB, CETP, ABCA1, APOA1
5cholestyramine4510.3CETP, APOB, APOC3
6ciprofibrate45 3011.3PON1, APOB, APOA1
7vitamin b124510.2CCL2, PON1, APOB, APOA1, HP
8vitamin-e4510.2HP, PON1, APOC3, CYBA, ABCA1
9kininogen4510.2ACE, HP, APOA1, APOB
10niacin45 1311.2APOA1, HP, ABCA1, APOB, CETP
11rosuvastatin45 51 30 1313.2APOA1, APOC3, CETP, APOB
12mspi4510.2APOC3, APOB, CETP, APOA1
13gemfibrozil30 45 1312.2CETP, PON1, APOA1, APOB, APOC3
14acipimox45 3011.2APOA1, APOB, CETP
15bezafibrate45 30 1312.2ABCA1, APOA1, APOC3, APOB, CETP
16alpha tocopherol4510.2APOB, PON1, ABCA1, APOA1, CETP
17triacylglycerol4510.2APOC3, APOA5, APOB, CETP, APOA1
187-ketocholesterol45 2611.1APOB, PON1, APOA1
19pioglitazone30 45 51 1313.1ABCA1, APOA1, APOB, CCL2
20rosiglitazone30 45 51 26 1314.1CCL2, APOB, APOC3, PON1, ABCA1
21probucol45 1311.1CCL2, CETP, APOB, APOA1, ABCA1, HP
22thyroxine45 2611.1HP, CETP, PON1, APOA1, APOB
23lovastatin45 51 61 30 1314.1APOB, APOC3, APOA1, CETP, PON1, APOA5
24uric acid45 2611.1APOB, APOA1, HP, PON1
25phosphatidylcholine4510.1CETP, APOA1, APOB, PON1, CCL2, ABCA1
26vitamin a45 26 1312.0HP, APOA1, APOB, APOC3, PON1, CETP
27xbai4510.0CETP, APOC3, APOB
28cholesterol ester4510.0CETP, HP, PON1, APOB, ABCA1, APOA1
29glutamine4510.0PON1, CYBA, APOB, CETP, MEF2A, CCL2
30fluvastatin45 51 30 1313.0APOA1, CCL2, ACE, CETP, PON1, APOB
31homocysteine45 2611.0HP, APOC3, APOB, PON1, CETP, CCL2
32fatty acid4510.0APOC3, ABCA1, APOA5, APOB, CETP, MEF2A
33phospholipid4510.0APOC3, APOB, ABCA1, PON1, APOA1, HP
34heparin45 30 26 1312.9P2RY12, PON1, APOB, APOA5, APOC3, CETP
35fenofibrate45 51 1311.9ABCA1, APOA1, APOC3, APOA5, APOB, PON1
36simvastatin45 51 61 30 26 1314.9PON1, CCL2, CETP, APOB, APOA5, APOA1
37aspirin45 51 30 2612.9ACE, P2RY12, PON1, APOB, APOA1, ABCA1
38pravastatin45 51 30 26 1313.9ABCA1, APOC3, PON1, ACE, CCL2, CETP
39fibrinogen459.9APOC3, CCL2, HP, APOB, PON1, APOA1
40nitric oxide45 26 1311.8HP, ACE, CCL2, APOC3, CYBA, TERT
41hind iii459.8HP, ABCA1, APOC3
42atorvastatin45 51 30 26 1313.8ABCA1, APOA1, APOC3, CCL2, APOA5, APOB
43testosterone45 61 26 1312.8HP, CCL2, CETP, APOC3, TERT, APOB
44creatinine459.8CCL2, MEF2A, P2RY12, PON1, APOC3, APOA1
45polysaccharide459.7HP, APOC3, APOB, PON1, CCL2
46serine459.6APOB, APOC3, APOA1, TERT, ABCA1, PON1
47estrogen459.6APOC3, HP, CETP, PON1, APOB, APOA1
48glucose459.5HP, PON1, APOB, MEF2A, APOC3, APOA1
49cholesterol45 30 26 1312.5APOB, CETP, ACE, PON1, CCL2, APOA5
50lipid459.3APOA1, ABCA1, APOB, TERT, CYBA, APOC3

GO Terms for genes affiliated with Coronary Artery Disease

About this section

Cellular components related to Coronary Artery Disease according to GeneCards/GeneDecks:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1spherical high-density lipoprotein particleGO:003436610.3APOA1, APOC3, PON1
2chylomicronGO:004262710.2APOC3, APOA5, APOB
3endocytic vesicle lumenGO:007168210.1HP, APOB, APOA1
4blood microparticleGO:007256210.1HP, PON1, APOA1
5high-density lipoprotein particleGO:003436410.1APOA1, APOA5, APOC4, PON1, CETP
6intermediate-density lipoprotein particleGO:003436310.1APOB, APOC3
7very-low-density lipoprotein particleGO:003436110.1APOB, APOC4, APOA5, APOC3, APOA1
8early endosomeGO:00057699.9LRP6, APOA1, APOC3, APOB
9low-density lipoprotein particleGO:00343629.9APOB, APOA5
10extracellular spaceGO:00056159.5APOA1, APOC3, APOA5, APOB, PON1, CETP
11extracellular regionGO:00055769.5APOA1, APOC3, APOA5, APOB, PON1, CETP

Biological processes related to Coronary Artery Disease according to GeneCards/GeneDecks:

(show all 37)
idNameGO IDScoreTop Affiliating Genes
1high-density lipoprotein particle assemblyGO:003438010.5ABCA1, APOA1
2negative regulation of very-low-density lipoprotein particle remodelingGO:001090310.5APOC3, APOA1
3lipoprotein biosynthetic processGO:004215810.5APOA1, APOB
4cerebral cortex cell migrationGO:002179510.5LRP6, CX3CR1
5phosphatidylcholine metabolic processGO:004647010.5PON1, CETP
6triglyceride mobilizationGO:000664210.5APOC3, APOB
7phospholipid homeostasisGO:005509110.5ABCA1, APOA1, CETP
8regulation of Cdc42 protein signal transductionGO:003248910.5APOC3, APOA1, ABCA1
9phospholipid effluxGO:003370010.5ABCA1, APOA1, APOC3
10organ regenerationGO:003110010.5CCL2, APOA5, APOA1
11triglyceride catabolic processGO:001943310.4APOB, APOA5, APOC3
12positive regulation of cholesterol effluxGO:001087510.4ABCA1, PON1
13cellular response to lipopolysaccharideGO:007122210.4ABCA1, CX3CR1, CCL2
14triglyceride metabolic processGO:000664110.4APOC3, APOA5, CETP
15high-density lipoprotein particle remodelingGO:003437510.4APOA1, APOC3, CETP
16very-low-density lipoprotein particle assemblyGO:003437910.4APOC3, APOB
17cholesterol transportGO:003030110.4APOA1, APOB, CETP
18low-density lipoprotein particle remodelingGO:003437410.4APOB, CETP
19retinoid metabolic processGO:000152310.4APOA1, APOC3, APOB
20cellular response to tumor necrosis factorGO:007135610.4CCL2, APOB, CYBA
21negative regulation of macrophage derived foam cell differentiationGO:001074510.4CETP, ABCA1
22response to nutrientGO:000758410.4APOC3, APOA1, ABCA1
23cellular response to cholesterolGO:007139710.4LRP6, ABCA1
24reverse cholesterol transportGO:004369110.3CETP, APOC3, APOA1, ABCA1
25macrophage chemotaxisGO:004824610.3CX3CR1, CCL2
26cholesterol effluxGO:003334410.3ABCA1, APOA1, APOC3, APOB
27phototransduction, visible lightGO:000760310.3APOB, APOC3, APOA1
28triglyceride homeostasisGO:007032810.2APOA1, APOC3, APOA5, APOC4, CETP
29G-protein coupled receptor signaling pathwayGO:000718610.2CCL2, CX3CR1, APOC3, APOA1, ABCA1
30response to drugGO:004249310.2ABCA1, CYBA, APOA1, APOC3, CCL2
31cholesterol metabolic processGO:000820310.2ABCA1, APOA1, APOC3, APOB, CETP
32lipoprotein transportGO:004295310.2APOC3, APOB
33cellular lipid metabolic processGO:004425510.1APOA5, APOA1, ABCA1
34lipoprotein metabolic processGO:004215710.1CETP, APOB, APOA5, APOC3, APOA1, ABCA1
35cholesterol homeostasisGO:004263210.1ABCA1, APOA1, APOC3, APOA5, APOB, CETP
36chemotaxisGO:000693510.0C5AR2, CCL2, CX3CR1
37small molecule metabolic processGO:00442819.4ABCA1, APOA1, APOC3, APOA5, APOB, CETP

Molecular functions related to Coronary Artery Disease according to GeneCards/GeneDecks:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1lipase bindingGO:003547310.4APOB, APOA5
2high-density lipoprotein particle receptor bindingGO:007065310.4APOA1, APOC3
3lipase inhibitor activityGO:005510210.3APOA1, APOC3
4low-density lipoprotein particle receptor bindingGO:005075010.3APOB, APOA5
5phospholipid transporter activityGO:000554810.3CETP, APOA1, ABCA1
6apolipoprotein bindingGO:003418510.2ABCA1, LRP6
7cholesterol transporter activityGO:001712710.2ABCA1, APOA1, APOB, CETP
8cholesterol bindingGO:001548510.2ABCA1, APOA1, APOC3, CETP
9phosphatidylcholine bindingGO:003121010.1APOA5, CETP
10heparin bindingGO:000820110.1CCL2, APOB, APOA5
11phospholipid bindingGO:000554310.0PON1, APOB, APOA5, APOC3, APOA1, ABCA1
12lipid transporter activityGO:00053199.9CETP, APOC4
13protein bindingGO:00055159.2ABCA1, TERT, LRP6, CYBA, APOA1, APOB

Products for genes affiliated with Coronary Artery Disease

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Coronary Artery Disease

About this section
4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet