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MCID: CRN019
MIFTS: 40

Coronary Artery Vasospasm malady

Categories: Cardiovascular diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Coronary Artery Vasospasm

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Aliases & Descriptions for Coronary Artery Vasospasm:

Name: Coronary Artery Vasospasm 12 14 69
Coronary Vasospasm 12 52 42
Coronary Artery Spasm 12 29

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:11840
MeSH 42 D003329
NCIt 47 C34515
SNOMED-CT 64 23687008
UMLS 69 C0010073
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Summaries for Coronary Artery Vasospasm

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MalaCards based summary : Coronary Artery Vasospasm, also known as coronary vasospasm, is related to myocardial infarction and proliferating trichilemmal cyst, and has symptoms including angina pectoris An important gene associated with Coronary Artery Vasospasm is EDN1 (Endothelin 1), and among its related pathways/superpathways are Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics and Calcium signaling pathway. The drugs Simvastatin and Hydrochlorothiazide have been mentioned in the context of this disorder. Affiliated tissues include heart, thyroid and brain, and related phenotype is muscle.

Wikipedia : 71 Coronary vasospasm is a sudden, intense vasoconstriction of an epicardial coronary artery that causes... more...

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Related Diseases for Coronary Artery Vasospasm

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Diseases related to Coronary Artery Vasospasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
id Related Disease Score Top Affiliating Genes
1 myocardial infarction 29.6 EDN1 KNG1 NOS3 TNNI3
2 proliferating trichilemmal cyst 10.2 EDN1 NOS3
3 ectodermal dysplasia 9, hair/nail type 10.2 EDN1 NOS3
4 renovascular hypertension 10.2 EDN1 NOS3
5 aplasia cutis congenita recessive 10.2 EDN1 NOS3
6 traumatic glaucoma 10.2 EDN1 NOS3
7 adenocarcinoma 10.2 EDN1 HTR7
8 lymphadenitis 10.2 EDN1 NOS3
9 aphasia 10.2 EDN1 NOS3
10 hematocele of tunica vaginalis testis 10.2 EDN1 HTR7
11 poikiloderma with neutropenia 10.2 EDN1 NOS3
12 alpha-2-plasmin inhibitor deficiency 10.2 EDN1 NOS3
13 zellweger syndrome 10.2 EDN1 NOS3
14 capillary hemangioma 10.2 EDN1 NOS3
15 vitreous disease 10.2 NOS3 TNNI3
16 acute posterior multifocal placoid pigment epitheliopathy 10.2 EDN1 NOS3
17 oppositional defiant disorder 10.1 EDN1 NOS3
18 dry eye syndrome 10.1 HTR2A HTR7
19 neurogenic bladder 10.1 HTR2A HTR7
20 allergic hypersensitivity disease 10.1 HTR2A HTR7
21 vascular cancer 10.1 HTR2A HTR7
22 pyelonephritis 10.1 EDN1 NOS3
23 fiedler's myocarditis 10.1 EDN1 NOS3
24 hepatic infarction 10.1 EDN1 KNG1
25 epileptic encephalopathy, early infantile, 9 10.1 NOS3 TNNI3
26 limb ischemia 10.0 EDN1 HTR2A NOS3
27 acute myocardial infarction 10.0
28 diabetic encephalopathy 10.0 EDN1 HTR2A NOS3
29 petrositis 10.0 EDN1 KNG1
30 myositis fibrosa 10.0 AHSP EDN1 TNNI3
31 keratosis 10.0 HTR2A HTR7
32 xanthogranulomatous pyelonephritis 10.0 EDN1 NOS3 TNNI3
33 alzheimer disease 17 9.9 HTR2A HTR7
34 viral hepatitis 9.9 EDN1 KNG1 NOS3
35 mucinous ovarian cystadenoma 9.9 EDN1 KNG1 NOS3
36 pericarditis 9.9 EDN1 KNG1 NOS3
37 macular degeneration, age-related, 12 9.9 EDN1 KNG1 NOS3
38 hypertension, essential 9.9 EDN1 KNG1 NOS3
39 atherosclerosis 9.9
40 acute myocarditis 9.9
41 myocarditis 9.9
42 acute closed-angle glaucoma 9.9 ABCC9 EDN1
43 brugada syndrome 9.7
44 churg-strauss syndrome 9.7
45 ischemia 9.7
46 thyroiditis 9.7
47 vasculitis 9.7
48 cardiomyopathy 9.7
49 pyrimidine metabolic disorder 9.7 EDN1 KNG1 NOS3 TNNI3
50 indeterminate leprosy 8.9 ABCC9 AHSP EDN1 HTR2A HTR7 KNG1

Graphical network of the top 20 diseases related to Coronary Artery Vasospasm:



Diseases related to Coronary Artery Vasospasm
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Symptoms & Phenotypes for Coronary Artery Vasospasm

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UMLS symptoms related to Coronary Artery Vasospasm:


angina pectoris

MGI Mouse Phenotypes related to Coronary Artery Vasospasm:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 9.02 ABCC9 EDN1 HTR2A NOS3 TNNI3
Sources

Drugs & Therapeutics for Coronary Artery Vasospasm

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Drugs for Coronary Artery Vasospasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 288)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Simvastatin Approved Phase 4 79902-63-9 54454
2
Hydrochlorothiazide Approved, Vet_approved Phase 4 58-93-5 3639
3
Losartan Approved Phase 4,Early Phase 1 114798-26-4 3961
4
Everolimus Approved Phase 4 159351-69-6 6442177
5
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
6
Sirolimus Approved, Investigational Phase 4 53123-88-9 5284616 6436030 46835353
7
Cocaine Approved, Illicit Phase 4,Phase 2,Phase 1 50-36-2 5760 446220
8
Dopamine Approved Phase 4,Phase 2,Phase 1 51-61-6, 62-31-7 681
9
Epinephrine Approved, Vet_approved Phase 4,Phase 1 51-43-4 5816
10
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 1 76631-46-4, 113775-47-6 68602 5311068 56032
11
Amlodipine Approved Phase 4 88150-42-9 2162
12
Oxytocin Approved, Vet_approved Phase 4 50-56-6 439302 53477758
13
Spironolactone Approved Phase 4,Phase 3 1952-01-7, 52-01-7 5833
14
Carvedilol Approved, Investigational Phase 4 72956-09-3 2585
15
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
16
Yohimbine Approved, Vet_approved Phase 4 146-48-5 8969
17
Acetazolamide Approved, Vet_approved Phase 4 59-66-5 1986
18
Methazolamide Approved Phase 4 554-57-4 4100
19
Atenolol Approved Phase 4 29122-68-7 2249
20
Bisoprolol Approved Phase 4 66722-44-9 2405
21
Metformin Approved Phase 4 657-24-9 14219 4091
22
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
23
Remifentanil Approved Phase 4 132875-61-7 60815
24
Dalteparin Approved Phase 4 9041-08-1
25
Epoprostenol Approved Phase 4 61849-14-7, 35121-78-9 5280427 5282411
26
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
27
Menthol Approved Phase 4 2216-51-5 16666
28
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
29
Nebivolol Approved, Investigational Phase 4 152520-56-4, 99200-09-6, 118457-14-0 71301
30
Nitric Oxide Approved Phase 4,Phase 2,Phase 1,Early Phase 1 10102-43-9 145068
31
Ephedrine Approved Phase 4,Phase 2,Phase 3,Early Phase 1 299-42-3 9294
32
Norepinephrine Approved Phase 4,Phase 1,Early Phase 1 51-41-2 439260
33
Oxymetazoline Approved Phase 4,Phase 2,Phase 3,Early Phase 1 1491-59-4 4636
34
Phenylephrine Approved Phase 4,Phase 2,Phase 3,Early Phase 1 59-42-7 6041
35
Pseudoephedrine Approved Phase 4,Phase 2,Phase 3,Early Phase 1 90-82-4 7028
36
Amiloride Approved Phase 4 2016-88-8, 2609-46-3 16231
37
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
38
Ramipril Approved Phase 4 87333-19-5 5362129
39
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
40
Indapamide Approved Phase 4 26807-65-8 3702
41
Irbesartan Approved, Investigational Phase 4 138402-11-6 3749
42
Prazosin Approved Phase 4 19216-56-9 4893
43
Enalapril Approved, Vet_approved Phase 4,Phase 1 75847-73-3 5362032 40466924
44
Enalaprilat Approved Phase 4,Phase 1 76420-72-9 6917719
45
Doxazosin Approved Phase 4 74191-85-8 3157
46
Rosiglitazone Approved, Investigational Phase 4 122320-73-4 77999
47
Clopidogrel Approved, Nutraceutical Phase 4,Phase 3 120202-66-6, 113665-84-2 60606
48
Caffeine Approved, Nutraceutical Phase 4 58-08-2 2519
49 Anticholesteremic Agents Phase 4,Phase 3
50 Antimetabolites Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 166)
id Name Status NCT ID Phase
1 The Effect of Sarpogrelate and High Dose Statin on the Reduction of Coronary Spasm Unknown status NCT01674686 Phase 4
2 Monotherapy Versus Dual Therapy for Initial Treatment for Hypertension Unknown status NCT00994617 Phase 4
3 Assessment of Stent Strut Coverage and Endothelial Function After Drug-Eluting Stents Unknown status NCT01073111 Phase 4
4 Cardiac Effects of Oxytocin Administrated During Cesarean Section, Signs of Myocardial Ischemia Completed NCT00777166 Phase 4
5 Efficacy of Spironolactone in Cameroonian Diabetic Patients With Resistant Hypertension Completed NCT02426099 Phase 4
6 Carvedilol Post-intervention Long-term Administration in Large-scale Trial Completed NCT01155635 Phase 4
7 Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery Completed NCT01706952 Phase 4
8 Mechanisms for the Effect of Acetylcysteine on Renal Function After Exposure to Radiographic Contrast Material Completed NCT00558142 Phase 4
9 The Effect of an α2-Adrenoceptor Antagonist (Yohimbine) on Dynamic Autoregulation in the Human Middle Cerebral Artery and Ophthalmic Artery Completed NCT00814047 Phase 4
10 AZ, MZ, and the Pulmonary System Response to Hypoxia Completed NCT02760121 Phase 4
11 An Active-controlled, Clinical Trial to Assess Central Hemodynamic Effects of Bisoprolol in Hypertensive Patients (Central Hemodynamic Assessment Measured in Patient With HypertensION [CHAMPION]) Completed NCT01079962 Phase 4
12 The Metformin-FMD Trial Completed NCT01610401 Phase 4
13 Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery Completed NCT01569048 Phase 4
14 Epoprostenol in Pulmonary Embolism Completed NCT01014156 Phase 4
15 Comparison of Nebivolol and Metoprolol With Exercise and Angiotensin II in Hypertensive Patients Completed NCT01502787 Phase 4
16 Effects of Vasopressors on Immune Response Completed NCT02675868 Phase 4
17 Sequential Nephron Blockade vs. Dual Blockade Renin-angiotensin System + Bisoprolol in Resistant Arterial Hypertension Recruiting NCT02832973 Phase 4
18 Renal Artery Stenting in Patients With Documented Resistant Hypertension and Atherosclerotic Renal Artery Stenosis (ANDORRA) Recruiting NCT02539810 Phase 4
19 The Effect of Dexmedetomidine on Prevention of Postoperative Acute Kidney Injury in Patients Undergoing Aortic Surgery Recruiting NCT02607163 Phase 4
20 Effect of DPP4 Inhibition on Vasoconstriction Recruiting NCT02639637 Phase 4
21 Optimum Treatment for Drug-Resistant Hypertension Active, not recruiting NCT02369081 Phase 4
22 Renal Denervation in Hypertension Active, not recruiting NCT01570777 Phase 4
23 Rosiglitazone and Metformin: Outcomes Trial in Nondiabetic Patients With Stable Coronary Syndromes (Romance) Pilot Study Terminated NCT00343395 Phase 4
24 Clopidogrel Versus Adenosin in Non Urgent Percutaneous Coronary Intervention (PCI) Unknown status NCT00751491 Phase 3
25 Continued Safety and Performance of the TIVUS System Unknown status NCT01835535 Phase 2, Phase 3
26 Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Progenitor Cells and Coronary Atherosclerosis in Humans Completed NCT01067339 Phase 3
27 Rosuvastatin in Preventing Myonecrosis in Elective Percutaneous Coronary Interventions (PCIs) Completed NCT01007279 Phase 3
28 ROsuvastatin Pretreatment to Reduce MyocArdial Periprocedural Necrosis:Comparison With Atorvastatin Reloading Completed NCT01228227 Phase 3
29 The Effect of Spironolactone on Blood Pressure in Type-2 Diabetics With Resistant Hypertension Completed NCT01062763 Phase 3
30 Iloprost for Prevention of Contrast-Mediated Nephropathy in High-Risk Patients Undergoing Coronary Angiography and/or Intervention Completed NCT00345501 Phase 2, Phase 3
31 Phosphodiesterase-5 (PDE5) Inhibition and Pulmonary Hypertension in Diastolic Heart Failure Completed NCT01156636 Phase 2, Phase 3
32 Inflammatory Responses to Lipid Emulsions in Children Before and After Open Heart Surgery Completed NCT00336908 Phase 2, Phase 3
33 The Effects Of Bronchodilator Therapy On Respiratory And Autonomic Function In Patients With Familial Dysautonomia Completed NCT01987219 Phase 3
34 Albumin Administration in Patients With Cirrhosis and Infections Unrelated to Spontaneous Bacterial Peritonitis Completed NCT00124228 Phase 3
35 Comparison of Vasopressin and Other Pressors in Septic Shock Completed NCT00269685 Phase 2, Phase 3
36 Ephedrine and Phenylephrine for Spinal Hypotension Recruiting NCT03047109 Phase 2, Phase 3
37 To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites Recruiting NCT02649335 Phase 3
38 Is Peri-operative Hyperoxemia a Risk Factor for Postoperative Complications? Recruiting NCT02562781 Phase 3
39 Induced Hypertension for Treatment of Delayed Cerebral Ischaemia After Aneurysmal Subarachnoid Haemorrhage Terminated NCT01613235 Phase 3
40 Therapeutic Effect of Sildenafil in Patients With Coronary Vasospasm Withdrawn NCT00454714 Phase 3
41 Dexmedetomidine for Reversal of Cocaine's Effects on the Heart Unknown status NCT01927640 Phase 2
42 The Role of Endothelin in Pulmonary Hypertension Unknown status NCT00759408 Phase 2
43 Acetylcholinesterase Inhibition and Orthostatic Hypotension in SC I Unknown status NCT02307526 Phase 2
44 Paracetamol and Patent Ductus Arteriosus (PDA) Unknown status NCT01291654 Phase 2
45 Rapid Renal Sympathetic Denervation for Resistant Hypertension Completed NCT01520506 Phase 2
46 Addition of Homeopathy in Patients With Resistant Arterial Hypertension Completed NCT02124473 Phase 2
47 Combined Treatment of Resistant Hypertension and Atrial Fibrillation Completed NCT01117025 Phase 2
48 Remote Ischaemic Conditioning and Coronary Endothelial Function (RIC-COR) Completed NCT02666235 Phase 2
49 Exercise Oscillatory Breathing and Sildenafil in Heart Failure Completed NCT01185925 Phase 2
50 Effect of Oxygen During Percutaneous Coronary Intervention for Pain Relief Completed NCT01413841 Phase 2

Search NIH Clinical Center for Coronary Artery Vasospasm

Cochrane evidence based reviews: coronary vasospasm

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Genetic Tests for Coronary Artery Vasospasm

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Genetic tests related to Coronary Artery Vasospasm:

id Genetic test Affiliating Genes
1 Coronary Artery Spasm 29
Sources

Anatomical Context for Coronary Artery Vasospasm

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MalaCards organs/tissues related to Coronary Artery Vasospasm:

39
Heart, Thyroid, Brain
Sources

Publications for Coronary Artery Vasospasm

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Articles related to Coronary Artery Vasospasm:

(show all 46)
id Title Authors Year
1
Outcomes of Brugada Syndrome Patients with Coronary Artery Vasospasm. ( 28090040 )
2017
2
Life Threatening Complication of Self-made Remedy for Controlling High Blood Pressure-Coronary Artery Vasospasm Associated with Iatrogenic Thyrotoxicosis. ( 27826349 )
2016
3
Eosinophilia-Associated Coronary Artery Vasospasm in Patients with Aspirin-Exacerbated Respiratory Disease. ( 27396680 )
2016
4
IMAGES IN CLINICAL MEDICINE. Cocaine-Induced Coronary-Artery Vasospasm. ( 26840152 )
2016
5
Capecitabine-induced coronary artery vasospasm in a patient who previously experienced a similar episode with fluorouracil therapy. ( 26875134 )
2016
6
Feasible induction of coronary artery vasospasm occurred during cardiac catheterization in a microminipig. ( 26806564 )
2016
7
Scombroid fish poisoning illness and coronary artery vasospasm. ( 25870660 )
2015
8
Unraveling of the Effect of Nodose Ganglion Degeneration on the Coronary Artery Vasospasm after Subarachnoid Hemorrhage; an Experimental Study. ( 26365883 )
2015
9
Organophosphate poisoning with coronary artery vasospasm confirmed by angiography. ( 25302727 )
2014
10
Amiodarone-induced destructive thyroiditis associated with coronary artery vasospasm and recurrent ventricular fibrillation. ( 24783040 )
2013
11
Patients with left main coronary artery vasospasm inadvertently undergoing coronary artery bypass grafting surgery. ( 23428222 )
2013
12
A case of caffeine-induced coronary artery vasospasm of a 17-year-old male. ( 22231478 )
2012
13
A Case of Acute Myocardial Infarction With ST-Segment Elevation in a Lead Augmented Right Vector Caused by a Left Main Coronary Artery Vasospasm. ( 22363384 )
2012
14
Capecitabine may induce coronary artery vasospasm. ( 22796820 )
2012
15
Intraoperative coronary artery vasospasm: a twist in the tale! ( 22435284 )
2011
16
Reversible ischemia on treadmill exercise in left main coronary artery vasospasm. ( 22340417 )
2011
17
Sorafenib-associated multivessel coronary artery vasospasm. ( 21584715 )
2011
18
Multifocal severe coronary artery vasospasm mistaken for diffuse atherosclerosis: a case report. ( 20862333 )
2010
19
Acute coronary artery vasospasm associated with misoprostol for termination of pregnancy. ( 20224253 )
2010
20
A case report of 5-fluorouracil-induced coronary artery vasospasm. ( 22375089 )
2010
21
Coronary artery vasospasm and acute myocarditis: a rare association. ( 21428143 )
2010
22
Coronary artery vasospasm. A sudden spasm of the coronary arteries can feel like a heart attack. ( 20583353 )
2010
23
Early recognition of catheter-induced left main coronary artery vasospasm: implications for revascularization. ( 20665882 )
2010
24
Rare manifestations of Churg-Strauss syndrome: coronary artery vasospasm, temporal artery vasculitis, and reversible monocular blindness-a case report. ( 19034601 )
2009
25
Coronary artery vasospasm causing ventricular fibrillation - an external loop recording. ( 19195763 )
2009
26
Coronary artery vasospasm or true transient left ventricular apical ballooning? Differentiation by nuclear imaging. ( 18674728 )
2008
27
Eosinophilia and coronary artery vasospasm. ( 18718813 )
2008
28
Coronary artery vasospasm during awake deep brain stimulation surgery. ( 18534972 )
2008
29
ST-segment elevation in lead augmented vector right may also be caused by diffuse left main coronary artery vasospasm without fixed stenosis. ( 18404728 )
2008
30
Coronary artery vasospasm with iron sucrose. ( 17327282 )
2007
31
Coronary artery vasospasm causing acute myocardial infarction in a heart transplant recipient. ( 15737767 )
2005
32
Coronary artery vasospasm during dobutamine stress echocardiography. ( 15891761 )
2005
33
Secondary coronary artery vasospasm promotes cardiomyopathy progression. ( 14982859 )
2004
34
5-flurouracil induced coronary artery vasospasm. ( 15020524 )
2004
35
Acute myocardial infarction associated with myocardial bridge and coronary artery vasospasm. ( 12469991 )
2002
36
Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels. ( 12122112 )
2002
37
Amine metabolism: a novel path to coronary artery vasospasm. ( 11543647 )
2001
38
Use of exercise myocardial perfusion imaging to guide and assess the effectiveness of medical therapy in coronary artery vasospasm. ( 9588677 )
1998
39
Ephedrine-induced coronary artery vasospasm in a patient with prior cocaine use. ( 9085987 )
1997
40
Positron emission tomography with oxygen-15 of stunned myocardium caused by coronary artery vasospasm after recovery. ( 7888266 )
1995
41
Coronary artery vasospasm complicating acute myocarditis. A rare association. ( 3176473 )
1988
42
Observations on increased susceptibility to coronary artery vasospasm during beta blockade. ( 2886035 )
1987
43
The importance of excluding coronary artery vasospasm before percutaneous transluminal coronary angioplasty. A case report. ( 2946085 )
1986
44
Coronary artery vasospasm during treatment with intravenous nitroglycerin. ( 3930071 )
1985
45
Coronary artery vasospasm and emotional stress: a hypothetical link to atherosclerosis. ( 6270513 )
1981
46
Coronary artery vasospasm: the likely immediated cause of acute myocardial infarction. ( 380605 )
1979
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Variations for Coronary Artery Vasospasm

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Expression for Coronary Artery Vasospasm

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Search GEO for disease gene expression data for Coronary Artery Vasospasm.
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Pathways for Coronary Artery Vasospasm

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Pathways related to Coronary Artery Vasospasm according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics 58
Show member pathways
 11.22 KNG1 NOS3
2
Calcium signaling pathway 37
Show member pathways
 11.07 HTR2A HTR7 NOS3
3
HIF1Alpha Pathway 60
10.99 EDN1 NOS3
4
Endothelin Pathways 1
10.69 EDN1 NOS3
5
Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics 58
10.4 HTR2A HTR7
Sources

GO Terms for Coronary Artery Vasospasm

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Cellular components related to Coronary Artery Vasospasm according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 caveola GO:0005901 8.96 HTR2A NOS3
2 sarcomere GO:0030017 8.62 ABCC9 TNNI3

Biological processes related to Coronary Artery Vasospasm according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.67 ABCC9 EDN1 HTR2A
2 regulation of blood pressure GO:0008217 9.55 EDN1 NOS3
3 positive regulation of MAP kinase activity GO:0043406 9.54 EDN1 HTR2A
4 positive regulation of cytosolic calcium ion concentration GO:0007204 9.54 EDN1 HTR2A KNG1
5 sensory perception of pain GO:0019233 9.52 EDN1 HTR2A
6 regulation of cardiac conduction GO:1903779 9.51 ABCC9 TNNI3
7 phosphatidylinositol 3-kinase signaling GO:0014065 9.48 EDN1 HTR2A
8 vasodilation GO:0042311 9.46 KNG1 NOS3
9 smooth muscle contraction GO:0006939 9.43 HTR2A HTR7
10 vasoconstriction GO:0042310 9.4 EDN1 HTR7
11 negative regulation of blood coagulation GO:0030195 9.32 EDN1 KNG1
12 negative regulation of potassium ion transport GO:0043267 9.26 HTR2A NOS3
13 artery smooth muscle contraction GO:0014824 9.16 EDN1 HTR2A
14 regulation of systemic arterial blood pressure by endothelin GO:0003100 8.96 EDN1 NOS3
15 regulation of blood vessel size GO:0050880 8.8 EDN1 KNG1 NOS3

Molecular functions related to Coronary Artery Vasospasm according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 G-protein coupled serotonin receptor activity GO:0004993 9.16 HTR2A HTR7
2 neurotransmitter receptor activity GO:0030594 8.96 HTR2A HTR7
3 serotonin binding GO:0051378 8.62 HTR2A HTR7
Sources

Sources for Coronary Artery Vasospasm

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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