MCID: CRN173
MIFTS: 18

Coronary Heart Disease 8 malady

Categories: Genetic diseases

Aliases & Classifications for Coronary Heart Disease 8

Aliases & Descriptions for Coronary Heart Disease 8:

Name: Coronary Heart Disease 8 54
Coronary Heart Disease, Susceptibility to, 8 13

Classifications:



External Ids:

OMIM 54 611139

Summaries for Coronary Heart Disease 8

MalaCards based summary : Coronary Heart Disease 8, is also known as coronary heart disease, susceptibility to, 8. An important gene associated with Coronary Heart Disease 8 is CHDS8 (Coronary Heart Disease, Susceptibility To, 8). The drugs Everolimus and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include heart.

Description from OMIM: 611139

Related Diseases for Coronary Heart Disease 8

Symptoms & Phenotypes for Coronary Heart Disease 8

Clinical features from OMIM:

611139

Drugs & Therapeutics for Coronary Heart Disease 8

Drugs for Coronary Heart Disease 8 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1253)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
2
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
3
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
4
Tirofiban Approved Phase 4,Phase 3 144494-65-5 60947
5
Citalopram Approved Phase 4,Phase 3,Phase 2 59729-33-8 2771
6
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 33069-62-4 36314
7
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 2,Phase 1 58-93-5 3639
8
Losartan Approved Phase 4,Phase 3,Phase 2,Phase 1 114798-26-4 3961
9
Amlodipine Approved Phase 4,Phase 2,Phase 3 88150-42-9 2162
10
Valsartan Approved, Investigational Phase 4,Phase 3,Phase 2 137862-53-4 60846
11
Colchicine Approved Phase 4,Phase 2 64-86-8 6167 2833
12
Ticagrelor Approved Phase 4,Phase 3,Phase 2 274693-27-5 9871419
13
Ticlopidine Approved Phase 4,Phase 3,Phase 2,Phase 1 55142-85-3 5472
14
Metoprolol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 37350-58-6, 51384-51-1 4171
15
Dopamine Approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 51-61-6, 62-31-7 681
16
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 54-31-9 3440
17
Nicorandil Approved Phase 4 65141-46-0 47528
18
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
19
Valproic Acid Approved, Investigational Phase 4,Phase 3 99-66-1 3121
20
Budesonide Approved Phase 4,Phase 3 51333-22-3 63006 5281004
21
Ipratropium Approved Phase 4,Phase 2 22254-24-6, 60205-81-4 43232
22
Terbutaline Approved Phase 4 23031-25-6 5403
23
Desflurane Approved Phase 4 57041-67-5 42113
24
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
25
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 2078-54-8 4943
26
Irbesartan Approved, Investigational Phase 4,Phase 2 138402-11-6 3749
27
Rifampin Approved Phase 4,Phase 3,Phase 2,Phase 1 13292-46-1 5458213 5381226
28
Vancomycin Approved Phase 4,Phase 2 1404-90-6 441141 14969
29
Candesartan Approved Phase 4,Phase 3,Phase 2 139481-59-7 2541
30
Lercanidipine Approved, Investigational Phase 4 100427-26-7 65866
31
Atenolol Approved Phase 4 29122-68-7 2249
32
Amiodarone Approved, Investigational Phase 4,Phase 3,Phase 2 1951-25-3 2157
33
Propafenone Approved Phase 4 54063-53-5 4932
34
Sotalol Approved Phase 4,Phase 3 959-24-0, 3930-20-9 5253
35
Warfarin Approved Phase 4,Phase 3,Phase 2,Phase 1 81-81-2 6691 54678486
36
Ketamine Approved, Vet_approved Phase 4,Phase 2,Phase 1 6740-88-1 3821
37
Sevoflurane Approved, Vet_approved Phase 4,Phase 2,Phase 1 28523-86-6 5206
38
Adalimumab Approved Phase 4,Phase 3,Phase 2 331731-18-1 16219006
39
Etanercept Approved, Investigational Phase 4 185243-69-0
40
Infliximab Approved Phase 4,Phase 3,Phase 2 170277-31-3
41
Gabapentin Approved, Investigational Phase 4,Phase 1 60142-96-3 3446
42
Fosfomycin Approved Phase 4 23155-02-4 446987
43
Imipenem Approved Phase 4 74431-23-5 104838
44
Guaifenesin Approved, Vet_approved Phase 4,Phase 1 93-14-1 3516
45
Methadone Approved Phase 4,Phase 1 76-99-3 4095
46
Spironolactone Approved Phase 4,Phase 3,Phase 2,Phase 1 1952-01-7, 52-01-7 5833
47
Nifedipine Approved Phase 4,Phase 3,Phase 1 21829-25-4 4485
48
Menthol Approved Phase 4,Phase 2,Phase 3,Phase 1 2216-51-5 16666
49
Acetylcholine Approved Phase 4,Phase 2,Phase 1 51-84-3 187
50
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1994-09-7, 94-09-7 2337

Interventional clinical trials:

(show top 50) (show all 2661)
id Name Status NCT ID Phase
1 Danshen Dropping Pill for Coronary Heart Disease Heart and Artery Structure and Function Unknown status NCT01825759 Phase 4
2 GISSOC II: Sirolimus Eluting Stent Versus Bare Metal Stent in Chronic Total Coronary Occlusions Unknown status NCT00220558 Phase 4
3 The Effects of Tirofiban in Diabetic Patients Undergoing Elective Percutaneous Coronary Intervention Unknown status NCT00407771 Phase 4
4 Optical Coherence Tomography Comparison of Neointimal Coverage Between CRE8 DES and BMS Unknown status NCT01543373 Phase 4
5 Prevention of Contrast Nephropathy During Diagnostic Coronary Angiogram or PCI With Hydratation Based on LEVDP Unknown status NCT00584350 Phase 4
6 DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome Unknown status NCT00140257 Phase 4
7 Fractional Flow Reserve Versus Angiography Randomization for Graft Optimization Trial Unknown status NCT02477371 Phase 4
8 Comparison of Diabetes Mellitus and Non-diabetes Mellitus Patients for DES Surface COVERage by OCT Unknown status NCT01021930 Phase 4
9 Periodontal Therapy in Coronary Artery Patients Unknown status NCT01609725 Phase 4
10 Monotherapy Versus Dual Therapy for Initial Treatment for Hypertension Unknown status NCT00994617 Phase 4
11 Study of Endothelial Dysfunction in Systemic Lupus and Its Role in Heart Disease Unknown status NCT00188188 Phase 4
12 Regression of Fatty Heart by Valsartan Therapy Unknown status NCT00745953 Phase 4
13 Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery Unknown status NCT01201070 Phase 4
14 Colchicine for Acute Coronary Syndromes Unknown status NCT01906749 Phase 4
15 Effects and Plasma Concentration of Ticagrelor, After Crushed and Non-crushed Intake, After Acute Coronary Syndrome Unknown status NCT02341729 Phase 4
16 Clopidogrel Reloading in Patients With NSTEACS Undergoing Percutaneous Coronary Intervention on Chronic Clopidogrel Therapy Unknown status NCT01572129 Phase 4
17 Early Routine Catheterisation After Alteplase Fibrinolysis vs. Primary PCI in Acute ST-elevation Myocardial Infarct Unknown status NCT01930682 Phase 4
18 Ability of Metoprolol to Alter the Exercise Induced Elevation of Catecholamines Unknown status NCT00885651 Phase 4
19 Dopamine in Acute Decompensated Heart Failure (DAD-HF) Trial Unknown status NCT00937092 Phase 4
20 Comparing Ticagrelor and Clopidogrel Pharmacodynamics After Thrombolysis Unknown status NCT02048085 Phase 4
21 Efficacy Study of Nicorandil on Neointima Unknown status NCT02328521 Phase 4
22 The Benefit of Prophylactic Anticonvulsant in Post Cardiac Arrest Syndrome With Induced Mild Hypothermia Unknown status NCT01083784 Phase 4
23 EvaluAtion of Predictive Value of Multisite Intracardiac EchoCardiography During Imaging of Structure and funCTION of Left Atrial Appendage in Comparison to Transesophageal Echocardiography Unknown status NCT01371279 Phase 4
24 Efficacy of a Pacemaker Algorithm in Promotion of the Intrinsic Heart Activity. Unknown status NCT00156741 Phase 4
25 LTOT in COPD Patients With Moderate Chronic Hypoxemia and Chronic Heart Failure Unknown status NCT00668408 Phase 4
26 Desflurane-induced Myocardial Protection Unknown status NCT02019797 Phase 4
27 Shensongyangxin Capsule in the Treatment of Sinus Bradycardia With Premature Ventricular Contractions Unknown status NCT01750775 Phase 4
28 Irbesartan and Adhesion Molecules in AF Unknown status NCT00613496 Phase 4
29 Pharmacokinetics/ Pharmacodynamics (PK/PD) Study of Vancomycin Unknown status NCT02443064 Phase 4
30 Effects of Antihypertensive Treatment in HIV Infected Patients: Candesartan Versus Lercanidipine Unknown status NCT00564057 Phase 4
31 Examining Genetic Influence on Response to Beta-Blocker Medications in People With Type 2 Diabetes Unknown status NCT00925119 Phase 4
32 Atrial Fibrillation and the Risk for Neurological Complications Unknown status NCT00357227 Phase 4
33 A Prospective Randomized Study Comparing Radiofrequency Energy With Cryoenergy Unknown status NCT00773539 Phase 4
34 Randomized Study of Radiofrequency- vs. Cryo-Ablation for Typical Isthmus-Dependent Atrial Flutter Unknown status NCT00196170 Phase 4
35 Antiarrhythmic Drugs Assessment in Preventing Atrial Fibrillation Unknown status NCT02145546 Phase 4
36 Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients Unknown status NCT01610141 Phase 4
37 Effect of the Addition of Ketamine to Sevoflurane Anesthesia in Electroconvulsive Therapy Unknown status NCT02267980 Phase 4
38 Heart Function in Rheumatoid Arthritis and Ankylosing Spondylitis Pre and Post-TNF Blocker Unknown status NCT01072058 Phase 4
39 Effects of Gabapentin Enacarbil on Arousals, Heart Rate, Blood Pressure and PLMs in Restless Legs Syndrome Unknown status NCT02424695 Phase 4
40 Fosfomycin Plus Imipenem for Treatment of Infective Endocarditis Unknown status NCT00871104 Phase 4
41 Renal Toxicity of Iodixanol and Iopromide in Patients With Renal Dysfunction Unknown status NCT01580046 Phase 4
42 Inspiratory Muscle Training in Patients With Autonomic Neuropathic Unknown status NCT00752440 Phase 4
43 Adjunct Methadone to Decrease the Duration of Mechanical Ventilation in the Medical Intensive Care Unit Unknown status NCT02025855 Phase 4
44 Effects of Spironolactone on Collagen Metabolism in Patients With Pulmonary Arterial Hypertension Unknown status NCT01468571 Phase 4
45 The Effects of Blood Pressure Reduction on Cerebral Perfusion and Cognition in the Elderly Population Unknown status NCT00966199 Phase 4
46 A Study of Nifecardia SRFC and Adalat OROS in the Treatment of Patients With Essential Hypertension Unknown status NCT00173667 Phase 4
47 Thyroid Study Type 2 Diabetes Mellitus (T2DM) Unknown status NCT01379170 Phase 4
48 Vitamin D Augmentation of Tekturna (Aliskiren) in Hypertension Unknown status NCT01472796 Phase 4
49 Endoesophageal Cryotherapy For Ablating Barrett's Esophagus and Early Stage Esophageal Cancer Unknown status NCT00628784 Phase 4
50 Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO Unknown status NCT01930331 Phase 4

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Genetic Tests for Coronary Heart Disease 8

Anatomical Context for Coronary Heart Disease 8

MalaCards organs/tissues related to Coronary Heart Disease 8:

39
Heart

Publications for Coronary Heart Disease 8

Variations for Coronary Heart Disease 8

Expression for Coronary Heart Disease 8

Search GEO for disease gene expression data for Coronary Heart Disease 8.

Pathways for Coronary Heart Disease 8

GO Terms for Coronary Heart Disease 8

Sources for Coronary Heart Disease 8

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