MCID: CRN030
MIFTS: 51

Coronary Stenosis malady

Categories: Cardiovascular diseases

Aliases & Classifications for Coronary Stenosis

Aliases & Descriptions for Coronary Stenosis:

Name: Coronary Stenosis 12 52 42 14 69
Coronary Artery Stenosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4248
MeSH 42 D023921
NCIt 47 C80427
SNOMED-CT 64 233970002
UMLS 69 C0242231

Summaries for Coronary Stenosis

MalaCards based summary : Coronary Stenosis, also known as coronary artery stenosis, is related to myocardial infarction and pericarditis, and has symptoms including angina pectoris An important gene associated with Coronary Stenosis is APOA1 (Apolipoprotein A1), and among its related pathways/superpathways are Lipoprotein metabolism and p53 Pathway (RnD). The drugs Aspirin and Everolimus have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and endothelial, and related phenotypes are Decreased free cholesterol and homeostasis/metabolism

Related Diseases for Coronary Stenosis

Diseases related to Coronary Stenosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 171)
id Related Disease Score Top Affiliating Genes
1 myocardial infarction 28.5 ACE ADIPOQ ALB APOA1 APOB APOE
2 pericarditis 28.0 ACE ADIPOQ ALB APOA1 APOB APOE
3 lupus erythematosus panniculitis 10.3 ACE APOE
4 coloboma of iris 10.3 CRP IL6
5 cutaneous sclerosis 10.2 CRP IL6
6 iron metabolism disease 10.2 ACE APOE CRP
7 toxic myocarditis 10.2 ACE CRP IL6
8 lupus erythematosus 10.2 ACE CRP IL6
9 shoulder impingement syndrome 10.2 ALB CRP IL6
10 pars planitis 10.2 ACE APOA1 APOE
11 autoimmune disease of central nervous system 10.2 CRP IL6 SERPINE1
12 unilateral multicystic dysplastic kidney 10.2 CRP IL6
13 fallopian tube serous adenocarcinoma 10.2 ALB CRP IL6
14 asphyxia neonatorum 10.2 ACE APOE PON1
15 plummer's disease 10.2 ALB CRP IL6
16 allergic bronchopulmonary aspergillosis 10.2 ALB CRP IL6
17 familial progressive cardiac conduction defect 10.2 ALB APOA1 APOE
18 chordoid meningioma 10.2 ALB CRP IL6
19 colon adenocarcinoma 10.2 ALB CRP IL6
20 central nervous system leiomyoma 10.2 ALB CRP IL6
21 asbestosis 10.1 ALB CRP IL6
22 alcoholic hepatitis 10.1 ACE IL6 SERPINE1
23 schizotypal personality disorder 10.1 ACE ALB CRP
24 contagious pustular dermatitis 10.1 ACE APOE PON1
25 neonatal hypoxic and ischemic brain injury 10.1 APOA1 IL6
26 bacterial meningitis 10.1 ALB CRP IL6
27 coronary artery disease 10.1
28 artery disease 10.1
29 foodborne botulism 10.1 ALB CRP IL6
30 neuroaxonal dystrophy 10.1 ICAM1 IL6 SERPINE1
31 xerophthalmia 10.1 CRP ICAM1 SERPINE1
32 pyelonephritis 10.1 ACE CRP ICAM1
33 dermatomycosis 10.1 ALB CRP ICAM1
34 leukocyte disease 10.1 ALB CRP SERPINE1
35 hyperuricemia, pulmonary hypertension, renal failure, and alkalosis 10.1 ALB CRP IL6
36 synovium cancer 10.1 CRP ICAM1 IL6
37 pulmonary eosinophilia 10.1 ALB CRP IL6
38 acute myocardial infarction 10.1
39 ischemia 10.1
40 neuropathy 10.1 CRP IL6 TLR4
41 membranoproliferative glomerulonephritis 10.1 ALB CRP IL6
42 neurofibroma of the heart 10.1 ALB APOE SERPINE1
43 myiasis 10.1 CRP IL6 TLR4
44 zap-70 deficiency 10.1 APOB APOE
45 blepharochalasis 10.1 CRP IL6 TLR4
46 infancy electroclinical syndrome 10.1 CRP IL6 TLR4
47 secretory diarrhea myopathy and deafness 10.1 ACE CRP IL6 SERPINE1
48 anogenital venereal wart 10.1 ACE ALB CRP
49 listeriosis 10.1 ACE ADIPOQ
50 keratoconus 4 10.1 APOB APOE

Graphical network of the top 20 diseases related to Coronary Stenosis:



Diseases related to Coronary Stenosis

Symptoms & Phenotypes for Coronary Stenosis

UMLS symptoms related to Coronary Stenosis:


angina pectoris

GenomeRNAi Phenotypes related to Coronary Stenosis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased free cholesterol GR00340-A-2 9.02 APOA1 APOB APOE CETP PCSK9

MGI Mouse Phenotypes related to Coronary Stenosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.22 ACE ADIPOQ ALB APOA1 APOB APOE
2 cardiovascular system MP:0005385 10.2 ACE ADIPOQ APOA1 APOB APOE CRP
3 cellular MP:0005384 10.09 APOE ICAM1 IL6 PON1 TLR4 ADIPOQ
4 immune system MP:0005387 10.02 ACE ADIPOQ APOB APOE CRP ICAM1
5 liver/biliary system MP:0005370 9.96 IL6 PCSK9 SERPINE1 TLR4 ACE ADIPOQ
6 adipose tissue MP:0005375 9.95 ACE ADIPOQ APOE IL6 SERPINE1 TLR4
7 integument MP:0010771 9.87 ADIPOQ APOA1 APOE ICAM1 IL6 SERPINE1
8 muscle MP:0005369 9.7 ADIPOQ ALB APOB APOE ICAM1 IL6
9 neoplasm MP:0002006 9.5 ADIPOQ ALB ICAM1 IL6 SERPINE1 TLR4
10 renal/urinary system MP:0005367 9.17 ACE ADIPOQ ALB APOE IL6 SERPINE1

Drugs & Therapeutics for Coronary Stenosis

Drugs for Coronary Stenosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 484)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
2
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
3
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
4
Cilostazol Approved Phase 4,Phase 3 73963-72-1 2754
5
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
6
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
7
Azathioprine Approved Phase 4 446-86-6 2265
8
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 2 79217-60-0, 59865-13-3 5284373 6435893
9
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
10
Mycophenolic acid Approved Phase 4 24280-93-1 446541
11
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 33069-62-4 36314
12
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
13
Menthol Approved Phase 4,Phase 3,Phase 2 2216-51-5 16666
14
Ezetimibe Approved Phase 4,Phase 3 163222-33-1 150311
15
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Phase 3 55-56-1 9552079 2713
16
Esmolol Approved Phase 4 103598-03-4, 81147-92-4 59768
17
Nicardipine Approved Phase 4 55985-32-5 4474
18
Amlodipine Approved Phase 4,Phase 3,Phase 1 88150-42-9 2162
19
Desflurane Approved Phase 4 57041-67-5 42113
20
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
21
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
22
Captopril Approved Phase 4 62571-86-2 44093
23
Trandolapril Approved Phase 4 87679-37-6 5484727
24
Spironolactone Approved Phase 4,Phase 3 1952-01-7, 52-01-7 5833
25
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2 58-61-7 60961
26
Pioglitazone Approved, Investigational Phase 4,Phase 3,Phase 2 111025-46-8 4829
27
Regadenoson Approved Phase 4,Phase 2 313348-27-5 219024
28
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 772 46507594
29
Nitroglycerin Approved, Investigational Phase 4,Phase 3,Phase 2 55-63-0 4510
30
Benzocaine Approved Phase 4 1994-09-7, 94-09-7 2337
31
Remifentanil Approved Phase 4 132875-61-7 60815
32
Fluvastatin Approved Phase 4,Phase 2 93957-54-1 1548972
33
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
34
Amiodarone Approved, Investigational Phase 4,Phase 3 1951-25-3 2157
35
Propafenone Approved Phase 4 54063-53-5 4932
36
Isosorbide Dinitrate Approved Phase 4,Phase 3 87-33-2 6883
37
Nitric Oxide Approved Phase 4,Phase 3,Phase 1 10102-43-9 145068
38
Quinapril Approved, Investigational Phase 4 85441-61-8 54892
39
Acetylcarnitine Approved, Investigational Phase 4 3040-38-8 1
40
Ticagrelor Approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 274693-27-5 9871419
41
Probucol Approved Phase 4 23288-49-5 4912
42
Diltiazem Approved Phase 4,Phase 2,Phase 3 42399-41-7 39186
43
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
44
Bisoprolol Approved Phase 4 66722-44-9 2405
45
Ramipril Approved Phase 4,Phase 1 87333-19-5 5362129
46
Pitavastatin Approved Phase 4 147511-69-1, 147526-32-7 6366718 5282452
47
Pravastatin Approved Phase 4 81093-37-0 54687
48
Aminocaproic Acid Approved, Investigational Phase 4 60-32-2 564
49
Abciximab Approved Phase 4 143653-53-6
50
Simvastatin Approved Phase 4,Phase 3 79902-63-9 54454

Interventional clinical trials:

(show top 50) (show all 1567)
id Name Status NCT ID Phase
1 Fractional Flow Reserve and Intravascular Ultrasound in Evaluating Intermediate Coronary Lesions Unknown status NCT01414361 Phase 4
2 Comparison of Fractional Flow Reserve and Intravascular Ultrasound Unknown status NCT01133015 Phase 4
3 Monitoring Response to Antiplatelet Therapy Unknown status NCT00327041 Phase 4
4 Trial to Assess the Everolimus-Eluting Coronary Stent System (PROMUS Element) for Coronary Revascularization Unknown status NCT01342822 Phase 4
5 Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - SAfety & EffectiveneSS of Drug-ElUting Stents & Anti-platelet REgimen Unknown status NCT01267734 Phase 4
6 Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing Unknown status NCT00698607 Phase 4
7 Study of Endothelial Dysfunction in Systemic Lupus and Its Role in Heart Disease Unknown status NCT00188188 Phase 4
8 Study to Evaluate Effect of Everolimus in Progression of Graft Vascular Illness on Patients With Heart Transplant Unknown status NCT00695344 Phase 4
9 COMPETE: A Clinical Evaluation of Chrono Carbostent Carbofilmâ„¢ Coated Stent Unknown status NCT00920283 Phase 4
10 Study of the Paclitaxel-Coated Balloon Catheter in Bifurcated Coronary Lesions Unknown status NCT01278186 Phase 4
11 Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia Unknown status NCT00247533 Phase 4
12 Effects of Celecoxib On Restenosis After Coronary Intervention and Evolution of Atherosclerosis Trial Unknown status NCT00500279 Phase 4
13 SCRIPPS V: Intracoronary Brachytherapy for Recurrent Restenosis After Multiple Drug-Eluting Stents Unknown status NCT00714545 Phase 4
14 Side Branch Predilatation Strategy in Coronary Bifurcation Lesion Stenting (SBPS) Unknown status NCT01430377 Phase 4
15 CT Coronary Angiogram Versus Traditional Care in Emergency Department Assessment of Potential ACS Unknown status NCT00933400 Phase 4
16 Treatment of Bifurcated Coronary Lesions With Cypherâ„¢-Stent Unknown status NCT00288535 Phase 4
17 Endothelial Progenitors in Aortic Stenosis: Association With Aortic Stenosis Progression and Severity Unknown status NCT02060071 Phase 4
18 BIfurcation Optimal Treatment Strategy With LYMus Eluting Dedicated Bifurcation Versus Convention Stent Randomized Study Unknown status NCT01430364 Phase 4
19 Comparing Carotid Stenting With Endarterectomy in Severe Asymptomatic Carotid Stenosis Unknown status NCT00772278 Phase 4
20 Fractional Flow Reserve Versus Angiography Randomization for Graft Optimization Trial Unknown status NCT02477371 Phase 4
21 The Effects of Ezetimibe on Coronary Plaque Volume in Patients With Acute Coronary Syndrome Unknown status NCT01068093 Phase 4
22 Efficacy and Safety of Paclitaxel-eluting Balloon for Treatment of Lesions in Native Small Coronary Arteries Unknown status NCT01903902 Phase 4
23 The Effect of Lipitor on Aortic Stenosis Unknown status NCT00590135 Phase 4
24 A Prospective, Randomized Trial of BVS Veruss EES in Patients Undergoing Coronary Stenting for Myocardial Infarction Unknown status NCT01942070 Phase 4
25 Firebird 2 Versus Excel Sirolimus-eluting Stent in Treating Real-world Patients With Coronary Artery Disease Unknown status NCT01373632 Phase 4
26 Comparison of Intravenous Injection of Calcium Antagonist and Beta-blockade on Endothelial Shear Stress of Coronary Artery Unknown status NCT01171911 Phase 4
27 Do Cobalt Chrome Stent and Paclitaxel-Eluting Stent Have Equivalent Clinical Result in Non-Complex Lesion? Unknown status NCT00852215 Phase 4
28 Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery Unknown status NCT01201070 Phase 4
29 Comparison of Stenting Versus Best Medical Therapy for Treatment of Ostial Renal Artery Stenosis: a Trial in Patients With Advanced Atherosclerosis Unknown status NCT00711984 Phase 4
30 Diagnostic Performance of Noninvasive Fractional Flow Reserve From Computed Tomography Unknown status NCT01747317 Phase 4
31 A Pilot Study Exploring Efficacy and Safety of Amlodipine in the Stented Angina Patients Unknown status NCT01120327 Phase 4
32 Desflurane-induced Myocardial Protection Unknown status NCT02019797 Phase 4
33 Medical and Endovascular Treatment of Atherosclerotic Renal Artery Stenosis (METRAS Study) Unknown status NCT01208714 Phase 4
34 A Randomized Trial of Angiotensin Receptor bLocker,Fimasartan, in Aortic Stenosis (ALFA Trial) Unknown status NCT01589380 Phase 4
35 GISSOC II: Sirolimus Eluting Stent Versus Bare Metal Stent in Chronic Total Coronary Occlusions Unknown status NCT00220558 Phase 4
36 Early Warning and Optimization Strategy in Carotid Endarterectomy Unknown status NCT01210937 Phase 4
37 The Effect of Vitamin A on Atherosclerosis Unknown status NCT01414972 Phase 4
38 Optimizing Infarct Size by Transforming Emergent Stenting Into an Elective Procedure Study Unknown status NCT01462188 Phase 4
39 Acute Haemodynamic Effects of Treatment With Angiotensin Converting Enzyme (ACE)-Inhibitors in Patients With Symptomatic Aortic Stenosis Unknown status NCT00252317 Phase 4
40 The Study of the Effects of Vitamin A on Immune System in Patients With Atherosclerosis Unknown status NCT00963222 Phase 4
41 Cardioversion vs. Catheter Ablation for Persistent Atrial Fibrillation Unknown status NCT00196209 Phase 4
42 A Prospective Randomized Study Comparing Radiofrequency Energy With Cryoenergy Unknown status NCT00773539 Phase 4
43 Clinical and Therapeutic Implications of Fibrosis in Hypertrophic Cardiomyopathy Unknown status NCT00879060 Phase 4
44 Trial Comparing Angiography and Angiography With IVUS for Treatment of Hemodialysis Access Failures Unknown status NCT02056704 Phase 4
45 A Clinical Trials of Quick-Acting Heart Reliever for Moderate Coronary Stenosis Completed NCT01513070 Phase 4
46 Rapid Diagnosis of Myocardial Damage and Coronary Stenosis With Magnetic Resonance Imaging (MRI) Completed NCT00188123 Phase 4
47 The Impact of Stent Deployment Techniques on Clinical Outcomes of Patient Treated With the CYPHER® Stent (S.T.L.L.R.) Completed NCT00403338 Phase 4
48 Physiologic Evaluation of Anomalous Right Coronary Artery Stenosis Completed NCT01133054 Phase 4
49 Excel Drug-Eluting Stent Pilot Clinical Registry Completed NCT00385905 Phase 4
50 Contrast Enhancement on Coronary Computed Tomographic Angiography Completed NCT02462044 Phase 4

Search NIH Clinical Center for Coronary Stenosis

Cochrane evidence based reviews: coronary stenosis

Genetic Tests for Coronary Stenosis

Anatomical Context for Coronary Stenosis

MalaCards organs/tissues related to Coronary Stenosis:

39
Heart, Testes, Endothelial, Brain, Neutrophil, Monocytes, Liver

Publications for Coronary Stenosis

Articles related to Coronary Stenosis:

(show top 50) (show all 585)
id Title Authors Year
1
Noninvasive measurement of pressure gradient across a coronary stenosis using phase contrast (PC)-MRI: A feasibility study. ( 28019028 )
2017
2
Correction to: Assessing Computational Fractional Flow Reserve From Optical Coherence Tomography in Patients With Intermediate Coronary Stenosis in the Left Anterior Descending Artery. ( 28062519 )
2017
3
Pressure- and flow-derived indices of coronary stenosis severity: old rivals, new allies. ( 27119376 )
2016
4
Usefulness of late gadolinium enhancement MRI combined with stress imaging in predictive significant coronary stenosis in new-diagnosed left ventricular dysfunction. ( 27668708 )
2016
5
Discordance Between Resting and Hyperemic Indices of Coronary Stenosis Severity: The VERIFY 2 Study (A Comparative Study of Resting Coronary Pressure Gradient, Instantaneous Wave-Free Ratio and Fractional Flow Reserve in an Unselected Population Referred for Invasive Angiography). ( 27834663 )
2016
6
Non-invasive assessment of the haemodynamic significance of coronary stenosis using fusion of cardiac computed tomography and 3D echocardiography. ( 27461212 )
2016
7
TCT-532 Morphometric assessment of hemodynamically severe coronary stenosis relevance with optical frequency domain imaging according to vessel diameter. ( 27969898 )
2016
8
Relationship between hsTnI and coronary stenosis in asymptomatic women with rheumatoid arthritis. ( 27686126 )
2016
9
Assessing Computational Fractional Flow Reserve From Optical Coherence Tomography in Patients With Intermediate Coronary Stenosis in the Left Anterior Descending Artery. ( 27502209 )
2016
10
Regarding article, "A multi-artery fractional flow reserve (FFR) approach for handling coronary stenosis-stenosis interaction in the multi-vessel disease (MVD) arena". ( 27038690 )
2016
11
Quantification of coronary flow using dynamic angiography with 320-detector row CT and motion coherence image processing: Detection of ischemia for intermediate coronary stenosis. ( 27130062 )
2016
12
Comparison of visual assessment of coronary stenosis with independent quantitative coronary angiography: Findings from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial. ( 27892881 )
2016
13
Acquired intracoronary ADAMTS13 deficiency and VWF retention at sites of critical coronary stenosis in patients with STEMI. ( 27034431 )
2016
14
A Polylactide Bioresorbable Scaffold Eluting Everolimus for Treatment of Coronary Stenosis: 5-Year Follow-Up. ( 26892411 )
2016
15
Low forced expiratory volume in one second is associated with the history of acute coronary syndrome in patients with organic coronary stenosis. ( 26946928 )
2016
16
Angioplasty of unprotected left main coronary stenosis: Real world experience of a single-operator group from eastern India. ( 26896263 )
2016
17
Copeptin and high-sensitivity cardiac troponin to exclude severe coronary stenosis in patients with chest pain and coronary artery disease. ( 26851061 )
2016
18
Reactive Myocardial Hyperemia for Functional Assessment of Coronary Stenosis Severity. ( 27993753 )
2016
19
TCT-504 Comparison of Computed Tomography derived Fractional Flow Reserve to invasive Fractional Flow Reserve in Diagnosis of Functional Coronary Stenosis: A Meta-Analysis. ( 27969867 )
2016
20
Coronary Stenosis Associated with a Giant Coronary Aneurysm. ( 26626563 )
2016
21
Takotsubo Cardiomyopathy With Significant Coronary Stenosis and Atrioventricular Conduction Block: A Rare Case Report With 3 Year Follow-Up. ( 26866012 )
2016
22
Fractional Flow Reserve Assessment of a Significant Coronary Stenosis Masked by a Downstream Serial Lesion. ( 27529035 )
2016
23
Simultaneous rota-stenting and transcatheter aortic valve implantation for patients with heavily calcified coronary stenosis and aortic stenosis. ( 27344931 )
2016
24
Impact of monochromatic coronary computed tomography angiography from single-source dual-energy CT on coronary stenosis quantification. ( 26754621 )
2016
25
Intraoperative imaging to detect coronary stenosis in no-angiography patients. ( 27117303 )
2016
26
Coronary Flow Reserve and Microcirculatory Resistance in Patients With Intermediate Coronary Stenosis. ( 26965536 )
2016
27
Detection of Coronary Stenosis at RestA UsingA BOLD-CMR. ( 27424243 )
2016
28
Pre-test probability of obstructive coronary stenosis in patients undergoing coronary CT angiography: Comparative performance of the modified diamond-Forrester algorithm versus methods incorporating cardiovascular risk factors. ( 27500762 )
2016
29
Efficacy of pressure parameters obtained during contrast medium-induced submaximal hyperemia in the functional assessment of intermediate coronary stenosis in comparison with instantaneous wave-free ratio. ( 26851699 )
2016
30
Association of Coronary Stenosis and Plaque Morphology With Fractional Flow Reserve and Outcomes. ( 27438119 )
2016
31
REPLY: A multi-artery fractional flow reserve (FFR) approach for handling coronary stenosis-stenosis interaction in the multi-vessel disease (MVD) arena. ( 26800125 )
2016
32
Troponin I Assay for Identification of a Significant Coronary Stenosis in Patients with Suspected Acute Myocardial Infarction and Wide QRS Complex. ( 27148734 )
2016
33
The Diagnostic Performance of Coronary CT Angiography for the Assessment of Coronary Stenosis in Calcified Plaque. ( 27149622 )
2016
34
Diagnostic performance of instantaneous wave-free ratio for the evaluation of coronary stenosis severity confirmed by fractional flow reserve: A PRISMA-compliant meta-analysis of randomized studies. ( 27603377 )
2016
35
Brief Report: Intestinal Microbiota-Produced Trimethylamine-N-Oxide and Its Association With Coronary Stenosis and HIV Serostatus. ( 26825179 )
2016
36
The coronary calcium score is a more accurate predictor of significant coronary stenosis than conventional risk factors in symptomatic patients: Euro-CCAD study. ( 26784565 )
2016
37
Fractional flow reserve derived by coronary computed tomography angiography : AA sophisticated analysis method for detecting hemodynamically significant coronary stenosis. ( 27783095 )
2016
38
Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in ischemia-causing coronary stenosis: a meta-analysis. ( 27796727 )
2016
39
Modification of the association between smoking status and severity of coronary stenosis by vitamin D in patients suspected of coronary heart disease. ( 27603397 )
2016
40
Strain Imaging with a Bull's-Eye Map for Detecting Significant Coronary Stenosis during Dobutamine Stress Echocardiography. ( 27916236 )
2016
41
A Preoperative Assessment of Significant Coronary Stenosis Based on a Semiquantitative Analysis of Coronary Artery Calcification on Noncontrast Computed Tomography in Aortic Stenosis Patients Undergoing Aortic Valve Replacement. ( 26945385 )
2016
42
Reliability of Physiological Assessment of Coronary Stenosis Severity Using Intracoronary Pressure Techniques: A Comprehensive Analysis From a Large Cohort of Consecutive Intermediate Coronary Lesions. ( 27973333 )
2016
43
Enhanced Intestinal Absorption of Cholesterol along with Increased Chylomicron Remnants for De novo Progression of Coronary Stenosis. ( 27829581 )
2016
44
First-In-Man 6-month results of Qvanteq Surface-modified Coronary Stent System in Native Coronary Stenosis. ( 27993758 )
2016
45
Association between smoking habits and severity of coronary stenosis as assessed by coronary computed tomography angiography. ( 26187325 )
2015
46
Diagnosis of functionally significant coronary stenosis with exercise CT myocardial perfusion imaging. ( 25599157 )
2015
47
Chronotropic response to vasodilator-stress in patients submitted to myocardial perfusion imaging: impact on the accuracy in detecting coronary stenosis. ( 26194718 )
2015
48
Preoperative Coronary Stenosis Is a Determinant of Early Vascular Outcome after Carotid Endarterectomy. ( 26320844 )
2015
49
Progressively heterogeneous mismatch of regional oxygen delivery to consumption during graded coronary stenosis in pig left ventricle. ( 26408545 )
2015
50
Prospective Assessment of the Diagnostic Accuracy of Instantaneous Wave-Free Ratio to Assess Coronary Stenosis Relevance: Results of ADVISE II International, Multicenter Study (ADenosine Vasodilator Independent Stenosis Evaluation II). ( 25999106 )
2015

Variations for Coronary Stenosis

Expression for Coronary Stenosis

Search GEO for disease gene expression data for Coronary Stenosis.

Pathways for Coronary Stenosis

Pathways related to Coronary Stenosis according to GeneCards Suite gene sharing:

(show all 18)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.97 ALB APOA1 APOB APOE CETP PCSK9
2 11.88 ICAM1 SERPINE1 TLR4
3 11.86 ADIPOQ IL6 SERPINE1
4 11.82 ALB APOA1 APOE
5 11.79 ICAM1 IL6 TLR4
6 11.7 ICAM1 IL6 SERPINE1
7 11.68 IL6 SERPINE1 TLR4
8
Show member pathways
11.64 ICAM1 IL6 TLR4
9 11.61 ICAM1 IL6 TLR4
10
Show member pathways
11.57 ALB APOA1 APOB APOE
11
Show member pathways
11.56 ALB APOA1 APOB APOE CRP ICAM1
12 11.48 ICAM1 IL6 TLR4
13 11.3 ICAM1 IL6 TLR4
14
Show member pathways
11.29 APOA1 APOB APOE CETP
15 11.26 APOB ICAM1 IL6
16 11.09 ACE APOE TLR4
17 11.04 APOA1 ICAM1 IL6
18 10.84 CRP IL6

GO Terms for Coronary Stenosis

Cellular components related to Coronary Stenosis according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.93 ADIPOQ APOA1 ICAM1 PCSK9 TLR4
2 external side of plasma membrane GO:0009897 9.85 ACE ICAM1 IL6 TLR4
3 early endosome GO:0005769 9.83 APOA1 APOB APOE PCSK9
4 blood microparticle GO:0072562 9.8 ALB APOA1 APOE PON1
5 endoplasmic reticulum lumen GO:0005788 9.8 ALB APOA1 APOB APOE IL6 PCSK9
6 extracellular region GO:0005576 9.73 ACE ADIPOQ ALB APOA1 APOB APOE
7 very-low-density lipoprotein particle GO:0034361 9.65 APOA1 APOB APOE
8 endocytic vesicle lumen GO:0071682 9.63 APOA1 APOB APOE
9 low-density lipoprotein particle GO:0034362 9.61 APOA1 APOB APOE
10 chylomicron GO:0042627 9.58 APOA1 APOB APOE
11 spherical high-density lipoprotein particle GO:0034366 9.51 APOA1 PON1
12 high-density lipoprotein particle GO:0034364 9.46 APOA1 APOE CETP PON1
13 extracellular space GO:0005615 9.44 ACE ADIPOQ ALB APOA1 APOB APOE
14 intermediate-density lipoprotein particle GO:0034363 9.43 APOA1 APOB APOE
15 extracellular exosome GO:0070062 10.11 ACE ADIPOQ ALB APOA1 APOB APOE

Biological processes related to Coronary Stenosis according to GeneCards Suite gene sharing:

(show top 50) (show all 62)
id Name GO ID Score Top Affiliating Genes
1 post-translational protein modification GO:0043687 9.97 ALB APOA1 APOB APOE IL6 PCSK9
2 response to lipopolysaccharide GO:0032496 9.95 APOB ICAM1 IL6 TLR4
3 lipid transport GO:0006869 9.92 APOA1 APOB APOE CETP
4 cellular response to lipopolysaccharide GO:0071222 9.92 ICAM1 IL6 SERPINE1 TLR4
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.91 ICAM1 IL6 TLR4
6 platelet degranulation GO:0002576 9.9 ALB APOA1 SERPINE1
7 cellular response to tumor necrosis factor GO:0071356 9.9 APOB ICAM1 IL6
8 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.88 ADIPOQ ICAM1 IL6
9 negative regulation of inflammatory response GO:0050728 9.87 ADIPOQ APOA1 APOE
10 cellular protein metabolic process GO:0044267 9.85 ALB APOA1 APOB APOE IL6 PCSK9
11 retinoid metabolic process GO:0001523 9.84 APOA1 APOB APOE
12 response to nutrient levels GO:0031667 9.83 ADIPOQ IL6 PON1
13 defense response to Gram-negative bacterium GO:0050829 9.83 IL6 SERPINE1 TLR4
14 positive regulation of nitric oxide biosynthetic process GO:0045429 9.81 ICAM1 IL6 TLR4
15 triglyceride metabolic process GO:0006641 9.8 APOE CETP PCSK9
16 steroid metabolic process GO:0008202 9.8 APOA1 APOB APOE CETP PCSK9
17 receptor-mediated endocytosis GO:0006898 9.8 ALB APOA1 APOB APOE CETP PCSK9
18 triglyceride homeostasis GO:0070328 9.78 APOA1 APOE CETP
19 positive regulation of interleukin-8 production GO:0032757 9.77 ADIPOQ SERPINE1 TLR4
20 triglyceride catabolic process GO:0019433 9.77 APOA1 APOB APOE
21 low-density lipoprotein particle clearance GO:0034383 9.76 ADIPOQ APOB PCSK9
22 cholesterol efflux GO:0033344 9.75 APOA1 APOB APOE
23 cholesterol transport GO:0030301 9.74 APOA1 APOB CETP
24 negative regulation of tumor necrosis factor-mediated signaling pathway GO:0010804 9.73 ADIPOQ APOA1
25 positive regulation of chemokine production GO:0032722 9.73 IL6 TLR4
26 negative regulation of gluconeogenesis GO:0045721 9.72 ADIPOQ IL6
27 negative regulation of smooth muscle cell migration GO:0014912 9.72 ADIPOQ SERPINE1
28 reverse cholesterol transport GO:0043691 9.72 APOA1 APOE CETP
29 high-density lipoprotein particle assembly GO:0034380 9.71 APOA1 APOE
30 negative regulation of blood coagulation GO:0030195 9.71 APOE SERPINE1
31 phospholipid efflux GO:0033700 9.71 APOA1 APOE
32 phosphatidylcholine metabolic process GO:0046470 9.71 CETP PON1
33 cellular response to nutrient levels GO:0031669 9.71 ICAM1 IL6
34 positive regulation of cholesterol efflux GO:0010875 9.71 ADIPOQ APOE PON1
35 negative regulation of hormone secretion GO:0046888 9.7 ADIPOQ IL6
36 neutrophil mediated immunity GO:0002446 9.7 ACE IL6
37 negative regulation of macrophage derived foam cell differentiation GO:0010745 9.7 ADIPOQ CETP CRP
38 phospholipid homeostasis GO:0055091 9.69 APOA1 CETP
39 negative regulation of lipid storage GO:0010888 9.69 CRP IL6
40 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.69 ADIPOQ APOA1
41 low-density lipoprotein particle remodeling GO:0034374 9.69 APOB APOE CETP
42 positive regulation of cholesterol esterification GO:0010873 9.68 APOA1 APOE
43 high-density lipoprotein particle clearance GO:0034384 9.68 APOA1 APOE
44 regulation of receptor activity GO:0010469 9.68 PCSK9 SERPINE1
45 chylomicron remnant clearance GO:0034382 9.68 APOB APOE
46 very-low-density lipoprotein particle remodeling GO:0034372 9.67 APOE CETP
47 neuron projection regeneration GO:0031102 9.67 APOA1 APOE
48 receptor-mediated virion attachment to host cell GO:0046813 9.66 ACE ICAM1
49 very-low-density lipoprotein particle clearance GO:0034447 9.66 APOB APOE
50 lipoprotein biosynthetic process GO:0042158 9.65 APOA1 APOB APOE

Molecular functions related to Coronary Stenosis according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 lipid binding GO:0008289 9.72 ALB APOA1 APOB APOE CETP
2 cholesterol binding GO:0015485 9.58 APOA1 APOE CETP
3 phospholipid binding GO:0005543 9.56 APOA1 APOB APOE PON1
4 phospholipid transporter activity GO:0005548 9.51 APOA1 CETP
5 low-density lipoprotein particle binding GO:0030169 9.49 CRP PCSK9
6 lipoprotein particle binding GO:0071813 9.48 APOA1 APOE
7 phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 9.46 APOA1 APOE
8 lipid transporter activity GO:0005319 9.46 APOA1 APOB APOE CETP
9 very-low-density lipoprotein particle receptor binding GO:0070326 9.43 APOE PCSK9
10 apolipoprotein receptor binding GO:0034190 9.37 APOA1 PCSK9
11 cholesterol transporter activity GO:0017127 9.26 APOA1 APOB APOE CETP
12 low-density lipoprotein particle receptor binding GO:0050750 8.92 APOB APOE CRP PCSK9

Sources for Coronary Stenosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
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44 MGI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
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59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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