Aliases & Classifications for Coronary Stenosis

MalaCards integrated aliases for Coronary Stenosis:

Name: Coronary Stenosis 12 52 42 14 69
Coronary Artery Stenosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4248
MeSH 42 D023921
NCIt 47 C80427
SNOMED-CT 64 233970002
UMLS 69 C0242231

Summaries for Coronary Stenosis

MalaCards based summary : Coronary Stenosis, also known as coronary artery stenosis, is related to lymphoma and arthritis, and has symptoms including angina pectoris An important gene associated with Coronary Stenosis is APOA1 (Apolipoprotein A1), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and p53 Pathway (RnD). The drugs Aspirin and Everolimus have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and testes, and related phenotypes are Decreased free cholesterol and cardiovascular system

Related Diseases for Coronary Stenosis

Diseases related to Coronary Stenosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 194)
id Related Disease Score Top Affiliating Genes
1 lymphoma 30.0 ACE ALB IL6
2 arthritis 29.6 ACE APOE CETP PON1
3 ischemic heart disease 29.0 ACE ALB CRP IL6 SERPINE1
4 angina pectoris 28.3 ACE ALB APOA1 APOB CRP IL6
5 pericarditis 27.4 ACE APOA1 APOB APOE CETP CRP
6 myocardial infarction 24.7 ACE ALB APOA1 APOB APOE CETP
7 collagenopathy type 2 alpha 1 10.8 CRP IL6
8 crystal arthropathies 10.7 CRP IL6
9 shoulder impingement syndrome 10.7 CRP IL6
10 brachydactyly-distal symphalangism syndrome 10.7 CRP IL6
11 autoimmune hemolytic anemia, warm type 10.7 ACE APOE
12 drug rash with eosinophilia and systemic symptoms 10.7 APOA1 IL6
13 epstein-barr virus hepatitis 10.7 CRP IL6
14 x-linked dominant intellectual disability-epilepsy syndrome 10.6 CRP IL6
15 amelogenesis imperfecta, type iia3 10.6 APOA1 APOE
16 erythema elevatum diutinum 10.6 CRP IL6
17 cataract congenital autosomal dominant 10.6 CRP IL6
18 midline cystocele 10.6 CRP SERPINE1
19 conjunctival disease 10.5 ACE CETP
20 xk aprosencephaly 10.5 APOB APOE
21 capillary leak syndrome 10.5 ALB CRP
22 iron metabolism disease 10.5 ACE APOE CRP
23 small intestinal vasoactive intestinal peptide producing tumor 10.5 APOE CRP
24 placental abruption 10.5 ACE CRP IL6
25 hypercholesterolemia, due to ligand-defective apo b 10.5 APOB APOE
26 pancreatic acth hormone producing tumor 10.5 APOE CRP IL6
27 emphysema, congenital lobar 10.5 CRP IL6 PON1
28 delta-1-pyrroline-5-carboxylate dehydrogenase deficiency 10.5 APOB APOE
29 pars planitis 10.5 ACE APOA1 APOE
30 non-congenital cyst of kidney 10.4 ACE ALB
31 collagenous colitis 10.4 ACE SERPINE1
32 retinitis pigmentosa 70 10.4 ACE ALB
33 allergic bronchopulmonary aspergillosis 10.4 ALB CRP IL6
34 breast papillary carcinoma 10.4 ALB CRP IL6
35 plummer's disease 10.4 ALB CRP IL6
36 endocervical type cervical mucinous adenocarcinoma 10.4 ALB CRP IL6
37 carotid body cancer 10.4 ACE APOE PON1
38 alcohol abuse 10.4 ACE IL6 SERPINE1
39 speech and communication disorders 10.4 ALB CRP
40 colon adenocarcinoma 10.4 ALB CRP IL6
41 familial osteochondritis dissecans 10.3 ALB APOA1 APOE
42 brain meningioma 10.3 ALB APOE IL6
43 ostertagiasis 10.3 ACE IL6 TNNI3
44 adams-oliver syndrome 5 10.3 ACE CRP TNNI3
45 isthmus cancer 10.3 ALB CRP IL6
46 renal fibrosis 10.3 ACE IL6 TNNI3
47 pulmonary embolism 10.3 ALB CRP IL6
48 diamond-blackfan anemia 1 10.3 ALB CRP IL6
49 cystinosis 10.3 ACE ALB CRP
50 craniosynostosis 7 10.3 ACE CRP TNNI3

Graphical network of the top 20 diseases related to Coronary Stenosis:



Diseases related to Coronary Stenosis

Symptoms & Phenotypes for Coronary Stenosis

UMLS symptoms related to Coronary Stenosis:


angina pectoris

GenomeRNAi Phenotypes related to Coronary Stenosis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased free cholesterol GR00340-A-2 9.02 APOA1 APOB APOE CETP PCSK9

MGI Mouse Phenotypes related to Coronary Stenosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.11 IL6 PON1 SERPINE1 TLR4 TNNI3 ACE
2 homeostasis/metabolism MP:0005376 10.1 ACE ALB APOA1 APOB APOE CRP
3 liver/biliary system MP:0005370 9.91 ACE ALB APOA1 APOB APOE IL6
4 muscle MP:0005369 9.7 ALB APOB APOE ICAM1 IL6 TLR4
5 neoplasm MP:0002006 9.43 TLR4 ACE ALB ICAM1 IL6 SERPINE1
6 renal/urinary system MP:0005367 9.1 ACE ALB APOE IL6 SERPINE1 TLR4

Drugs & Therapeutics for Coronary Stenosis

Drugs for Coronary Stenosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 381)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
2
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
3
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
4
Cilostazol Approved Phase 4,Phase 3 73963-72-1 2754
5
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
6
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
7
Azathioprine Approved Phase 4 446-86-6 2265
8
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
9
Mycophenolic acid Approved Phase 4 24280-93-1 446541
10
Chromium Approved Phase 4,Phase 2,Phase 3,Phase 1 7440-47-3 27668
11
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 33069-62-4 36314
12
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
13
Menthol Approved Phase 4,Phase 3 2216-51-5 16666
14
Ezetimibe Approved Phase 4,Phase 3 163222-33-1 150311
15
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Phase 3 55-56-1 9552079 2713
16
Esmolol Approved Phase 4 103598-03-4, 81147-92-4 59768
17
Nicardipine Approved Phase 4 55985-32-5 4474
18
Amlodipine Approved Phase 4 88150-42-9 2162
19
Desflurane Approved Phase 4 57041-67-5 42113
20
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
21
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
22
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2 58-61-7 60961
23
Pioglitazone Approved, Investigational Phase 4,Phase 3,Phase 2 111025-46-8 4829
24
Regadenoson Approved Phase 4,Phase 2 313348-27-5 219024
25
Heparin Approved, Investigational Phase 4,Phase 2 9005-49-6 772 46507594
26
Nitroglycerin Approved, Investigational Phase 4,Phase 2 55-63-0 4510
27
Benzocaine Approved Phase 4 1994-09-7, 94-09-7 2337
28
Remifentanil Approved Phase 4 132875-61-7 60815
29
Fluvastatin Approved Phase 4,Phase 2 93957-54-1 1548972
30
Isosorbide Dinitrate Approved Phase 4 87-33-2 6883
31
Nitric Oxide Approved Phase 4,Phase 1 10102-43-9 145068
32
Quinapril Approved, Investigational Phase 4 85441-61-8 54892
33
Acetylcarnitine Approved, Investigational Phase 4 3040-38-8 1
34
Ticagrelor Approved Phase 4 274693-27-5 9871419
35
Probucol Approved Phase 4 23288-49-5 4912
36
Diltiazem Approved Phase 4 42399-41-7 39186
37
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
38
Bisoprolol Approved Phase 4 66722-44-9 2405
39
Ramipril Approved Phase 4 87333-19-5 5362129
40
Pitavastatin Approved Phase 4 147511-69-1, 147526-32-7 6366718 5282452
41
Pravastatin Approved Phase 4 81093-37-0 54687
42
Aminocaproic Acid Approved, Investigational Phase 4 60-32-2 564
43
Dobutamine Approved Phase 4,Phase 3 34368-04-2 36811
44
Liraglutide Approved Phase 4 204656-20-2 44147092
45
Nicorandil Approved Phase 4 65141-46-0 47528
46
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
47
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
48
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
49 Edoxaban Approved Phase 4 480449-70-5
50
Losartan Approved Phase 4 114798-26-4 3961

Interventional clinical trials:

(show top 50) (show all 1030)

id Name Status NCT ID Phase Drugs
1 Fractional Flow Reserve and Intravascular Ultrasound in Evaluating Intermediate Coronary Lesions Unknown status NCT01414361 Phase 4
2 Comparison of Fractional Flow Reserve and Intravascular Ultrasound Unknown status NCT01133015 Phase 4
3 Monitoring Response to Antiplatelet Therapy Unknown status NCT00327041 Phase 4
4 Trial to Assess the Everolimus-Eluting Coronary Stent System (PROMUS Element) for Coronary Revascularization Unknown status NCT01342822 Phase 4
5 Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - SAfety & EffectiveneSS of Drug-ElUting Stents & Anti-platelet REgimen Unknown status NCT01267734 Phase 4 Triple anti-platelet therapy (TAT);Double-dose clopidogrel anti-platelet therapy (DDAT)
6 Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing Unknown status NCT00698607 Phase 4 6-month clopidogrel therapy;12-month clopidogrel therapy
7 Study of Endothelial Dysfunction in Systemic Lupus and Its Role in Heart Disease Unknown status NCT00188188 Phase 4 quinipril
8 Study to Evaluate Effect of Everolimus in Progression of Graft Vascular Illness on Patients With Heart Transplant Unknown status NCT00695344 Phase 4 everolimus;azathioprine or mycophenolate mofetil
9 COMPETE: A Clinical Evaluation of Chrono Carbostent Carbofilm™ Coated Stent Unknown status NCT00920283 Phase 4
10 Study of the Paclitaxel-Coated Balloon Catheter in Bifurcated Coronary Lesions Unknown status NCT01278186 Phase 4
11 Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia Unknown status NCT00247533 Phase 4
12 Effects of Celecoxib On Restenosis After Coronary Intervention and Evolution of Atherosclerosis Trial Unknown status NCT00500279 Phase 4 Celecoxib
13 SCRIPPS V: Intracoronary Brachytherapy for Recurrent Restenosis After Multiple Drug-Eluting Stents Unknown status NCT00714545 Phase 4
14 Side Branch Predilatation Strategy in Coronary Bifurcation Lesion Stenting (SBPS) Unknown status NCT01430377 Phase 4
15 CT Coronary Angiogram Versus Traditional Care in Emergency Department Assessment of Potential ACS Unknown status NCT00933400 Phase 4
16 Treatment of Bifurcated Coronary Lesions With Cypher™-Stent Unknown status NCT00288535 Phase 4
17 Endothelial Progenitors in Aortic Stenosis: Association With Aortic Stenosis Progression and Severity Unknown status NCT02060071 Phase 4
18 BIfurcation Optimal Treatment Strategy With LYMus Eluting Dedicated Bifurcation Versus Convention Stent Randomized Study Unknown status NCT01430364 Phase 4
19 Fractional Flow Reserve Versus Angiography Randomization for Graft Optimization Trial Unknown status NCT02477371 Phase 4
20 The Effects of Ezetimibe on Coronary Plaque Volume in Patients With Acute Coronary Syndrome Unknown status NCT01068093 Phase 4 Ezetimibe
21 Efficacy and Safety of Paclitaxel-eluting Balloon for Treatment of Lesions in Native Small Coronary Arteries Unknown status NCT01903902 Phase 4
22 A Prospective, Randomized Trial of BVS Veruss EES in Patients Undergoing Coronary Stenting for Myocardial Infarction Unknown status NCT01942070 Phase 4
23 Firebird 2 Versus Excel Sirolimus-eluting Stent in Treating Real-world Patients With Coronary Artery Disease Unknown status NCT01373632 Phase 4
24 Comparison of Intravenous Injection of Calcium Antagonist and Beta-blockade on Endothelial Shear Stress of Coronary Artery Unknown status NCT01171911 Phase 4 Nicardipine , Esmolol
25 Do Cobalt Chrome Stent and Paclitaxel-Eluting Stent Have Equivalent Clinical Result in Non-Complex Lesion? Unknown status NCT00852215 Phase 4
26 Study of Administration Of Antithrombin in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery Unknown status NCT01201070 Phase 4 antithrombin III
27 Comparison of Stenting Versus Best Medical Therapy for Treatment of Ostial Renal Artery Stenosis: a Trial in Patients With Advanced Atherosclerosis Unknown status NCT00711984 Phase 4
28 Diagnostic Performance of Noninvasive Fractional Flow Reserve From Computed Tomography Unknown status NCT01747317 Phase 4
29 A Pilot Study Exploring Efficacy and Safety of Amlodipine in the Stented Angina Patients Unknown status NCT01120327 Phase 4 Placebo;Amlodipine
30 Desflurane-induced Myocardial Protection Unknown status NCT02019797 Phase 4 Desflurane
31 A Clinical Trials of Quick-Acting Heart Reliever for Moderate Coronary Stenosis Completed NCT01513070 Phase 4 Quick-Acting Heart Reliever;Isosorbide Dinitrate;Placebo of Isosorbide Dinitrate;Aspirin Enteric-coated Tablets;Placebo of Quick-Acting Heart Reliever;Aspirin Enteric-coated Tablets
32 Rapid Diagnosis of Myocardial Damage and Coronary Stenosis With Magnetic Resonance Imaging (MRI) Completed NCT00188123 Phase 4
33 The Impact of Stent Deployment Techniques on Clinical Outcomes of Patient Treated With the CYPHER® Stent (S.T.L.L.R.) Completed NCT00403338 Phase 4
34 Physiologic Evaluation of Anomalous Right Coronary Artery Stenosis Completed NCT01133054 Phase 4
35 Excel Drug-Eluting Stent Pilot Clinical Registry Completed NCT00385905 Phase 4
36 Contrast Enhancement on Coronary Computed Tomographic Angiography Completed NCT02462044 Phase 4 240 mg Iodine;300 mg Iodine;370 mg Iodine
37 Optical Coherence Tomography to Investigate FFR-Guided DEB-only Elective Coronary Angioplasty Completed NCT02120859 Phase 4
38 Kidney Damage in Patients With Moderate Fall in eGFR Completed NCT01136876 Phase 4 Iopamidol;Iodixanol-320
39 Kidney Damage in Patients With Normal eGFR Completed NCT01137786 Phase 4 Non ionic contrast media comparator;Non ionic contrast media comparator
40 SEA-SIDE: Sirolimus Versus Everolimus-eluting Stent Randomized Assessment in Bifurcated Lesions and Clinical SIgnificance of Residual siDE-branch Stenosis Completed NCT00697372 Phase 4
41 Z-SEA-SIDE: Sirolimus Versus Everolimus Versus Zotarolimus-eluting Stent Assessment in Bifurcated Lesions and Clinical SIgnificance of Residual siDE-branch Stenosis Completed NCT01200693 Phase 4
42 Vision II: Evaluation of GALILEO Intravascular Radiotherapy System Completed NCT00180583 Phase 4
43 The Effect of Pioglitazone on Neointima Volume and Inflammatory Markers Completed NCT00494559 Phase 4 Pioglitazone;Placebo
44 Women With Chest Pain and no Significant Coronary Artery Stenosis; A Study on Microvascular Resistance Completed NCT01582165 Phase 4 Rosuvastatin;Placebo.
45 Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth Completed NCT00349895 Phase 4
46 Cost-Effectiveness Study in the Reduction of Coronary Restenosis With Sirolimus-Eluting Stents Completed NCT00627900 Phase 4
47 Comparison of Zotarolimus-Eluting Stent vs Sirolimus-Eluting Stent for Diabetic Patients Completed NCT01186107 Phase 4
48 Comparison of Everolimus-Eluting Stent vs Sirolimus-Eluting Stent in Patients With DIABETES Mellitus Completed NCT00997763 Phase 4
49 Study of Unprotected Left Main Stenting Versus Bypass Surgery (LE MANS Study) Completed NCT00375063 Phase 4
50 Zotarolimus-Eluting Stent Versus Sirolimus-Eluting Stent and PacliTaxel-Eluting Stent for Coronary Lesions Completed NCT00418067 Phase 4

Search NIH Clinical Center for Coronary Stenosis

Cochrane evidence based reviews: coronary stenosis

Genetic Tests for Coronary Stenosis

Anatomical Context for Coronary Stenosis

MalaCards organs/tissues related to Coronary Stenosis:

39
Heart, Endothelial, Testes, Brain, Kidney, Liver, Monocytes

Publications for Coronary Stenosis

Articles related to Coronary Stenosis:

(show top 50) (show all 603)
id Title Authors Year
1
Outcomes of Coronary Artery Bypass and Stents for Unprotected Left Main Coronary Stenosis. ( 28223049 )
2017
2
Electronic Stethoscope for Coronary Stenosis Detection. ( 28431676 )
2017
3
Stenotic flow reserve derived from quantitative coronary angiography has modest but incremental value in predicting functionally significant coronary stenosis as evaluated by fractional flow reserve. ( 28164013 )
2017
4
Difference of coronary stenosis severity between systolic and diastolic phases in quantitative CT angiography. ( 28126251 )
2017
5
Clues to Discordance and Dissimilarity Between Coronary Stenosis and Lesion-Specific Ischemia. ( 28687541 )
2017
6
Propensity-Score Matched Comparison of Midterm Angiographic Outcomes of Sirolimus- Versus Everolimus- and Biolimus-Eluting Stents for De Novo Coronary Stenosis. ( 28484124 )
2017
7
Intravascular Images of Coronary Stenosis with Multiple Channels in a Patient with Antiphospholipid Syndrome: The Optical Coherence Tomography Findings. ( 28566597 )
2017
8
Quantification of left coronary bifurcation angles and plaques by coronary computed tomography angiography for prediction of significant coronary stenosis: A preliminary study with dual-source CT. ( 28346530 )
2017
9
Intermediate CD14(++)CD16(+) monocyte predicts severe coronary stenosis and extensive plaque involvement in asymptomatic individuals. ( 28239800 )
2017
10
Correction to: Assessing Computational Fractional Flow Reserve From Optical Coherence Tomography in Patients With Intermediate Coronary Stenosis in the Left Anterior Descending Artery. ( 28062519 )
2017
11
Noninvasive measurement of pressure gradient across a coronary stenosis using phase contrast (PC)-MRI: A feasibility study. ( 28019028 )
2017
12
Sestrins increase in patients with coronary artery disease and associate with the severity of coronary stenosis. ( 28732653 )
2017
13
Applicability of 3-Dimensional Quantitative Coronary Angiography-Derived Computed Fractional Flow Reserve for Intermediate Coronary Stenosis. ( 28331135 )
2017
14
Influence of the amount of myocardium subtended to a coronary stenosis on the index of microcirculatory resistance. Implications for the invasive assessment of microcirculatory function in ischemic heart disease. ( 28485281 )
2017
15
Influence of increased heart rate and aortic pressure on resting indices of functional coronary stenosis severity. ( 28905113 )
2017
16
Bioresorbable Scaffolds for Coronary Stenosis: When and How Based Upon Current Studies. ( 28299676 )
2017
17
Left main coronary stenosis: surgery still reigns. ( 28797009 )
2017
18
What Is the Optimal Revascularization Strategy for Left Main Coronary Stenosis? ( 28903135 )
2017
19
Three-year follow-up of patients with acetylcholine-induced coronary artery spasm combined with insignificant coronary stenosis. ( 28457560 )
2017
20
Chronic Periaortitis of Ascending Aorta With Bilateral Ostial Coronary Stenosis in a Young Female. ( 28431717 )
2017
21
Non-invasive assessment of the haemodynamic significance of coronary stenosis using fusion of cardiac computed tomography and 3D echocardiography. ( 27461212 )
2016
22
Relationship between hsTnI and coronary stenosis in asymptomatic women with rheumatoid arthritis. ( 27686126 )
2016
23
Takotsubo Cardiomyopathy With Significant Coronary Stenosis and Atrioventricular Conduction Block: A Rare Case Report With 3 Year Follow-Up. ( 26866012 )
2016
24
Acquired intracoronary ADAMTS13 deficiency and VWF retention at sites of critical coronary stenosis in patients with STEMI. ( 27034431 )
2016
25
Discordance Between Resting and Hyperemic Indices of Coronary Stenosis Severity: The VERIFY 2 Study (A Comparative Study of Resting Coronary Pressure Gradient, Instantaneous Wave-Free Ratio and Fractional Flow Reserve in an Unselected Population Referred for Invasive Angiography). ( 27834663 )
2016
26
REPLY: A multi-artery fractional flow reserve (FFR) approach for handling coronary stenosis-stenosis interaction in the multi-vessel disease (MVD) arena. ( 26800125 )
2016
27
Troponin I Assay for Identification of a Significant Coronary Stenosis in Patients with Suspected Acute Myocardial Infarction and Wide QRS Complex. ( 27148734 )
2016
28
TCT-532 Morphometric assessment of hemodynamically severe coronary stenosis relevance with optical frequency domain imaging according to vessel diameter. ( 27969898 )
2016
29
Detection of Coronary Stenosis at RestA UsingA BOLD-CMR. ( 27424243 )
2016
30
First-In-Man 6-month results of Qvanteq Surface-modified Coronary Stent System in Native Coronary Stenosis. ( 27993758 )
2016
31
Association of Coronary Stenosis and Plaque Morphology With Fractional Flow Reserve and Outcomes. ( 27438119 )
2016
32
Coronary Stenosis Associated with a Giant Coronary Aneurysm. ( 26626563 )
2016
33
Pressure- and flow-derived indices of coronary stenosis severity: old rivals, new allies. ( 27119376 )
2016
34
Strain Imaging with a Bull's-Eye Map for Detecting Significant Coronary Stenosis during Dobutamine Stress Echocardiography. ( 27916236 )
2016
35
Enhanced Intestinal Absorption of Cholesterol along with Increased Chylomicron Remnants for De novo Progression of Coronary Stenosis. ( 27829581 )
2016
36
Pre-test probability of obstructive coronary stenosis in patients undergoing coronary CT angiography: Comparative performance of the modified diamond-Forrester algorithm versus methods incorporating cardiovascular risk factors. ( 27500762 )
2016
37
Simultaneous rota-stenting and transcatheter aortic valve implantation for patients with heavily calcified coronary stenosis and aortic stenosis. ( 27344931 )
2016
38
Reliability of Physiological Assessment of Coronary Stenosis Severity Using Intracoronary Pressure Techniques: A Comprehensive Analysis From a Large Cohort of Consecutive Intermediate Coronary Lesions. ( 27973333 )
2016
39
Regarding article, "A multi-artery fractional flow reserve (FFR) approach for handling coronary stenosis-stenosis interaction in the multi-vessel disease (MVD) arena". ( 27038690 )
2016
40
Fractional flow reserve derived by coronary computed tomography angiography : AA sophisticated analysis method for detecting hemodynamically significant coronary stenosis. ( 27783095 )
2016
41
Angioplasty of unprotected left main coronary stenosis: Real world experience of a single-operator group from eastern India. ( 26896263 )
2016
42
Impact of monochromatic coronary computed tomography angiography from single-source dual-energy CT on coronary stenosis quantification. ( 26754621 )
2016
43
Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in ischemia-causing coronary stenosis: a meta-analysis. ( 27796727 )
2016
44
Fractional Flow Reserve Assessment of a Significant Coronary Stenosis Masked by a Downstream Serial Lesion. ( 27529035 )
2016
45
Assessing Computational Fractional Flow Reserve From Optical Coherence Tomography in Patients With Intermediate Coronary Stenosis in the Left Anterior Descending Artery. ( 27502209 )
2016
46
Usefulness of late gadolinium enhancement MRI combined with stress imaging in predictive significant coronary stenosis in new-diagnosed left ventricular dysfunction. ( 27668708 )
2016
47
Comparison of visual assessment of coronary stenosis with independent quantitative coronary angiography: Findings from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial. ( 27892881 )
2016
48
TCT-504 Comparison of Computed Tomography derived Fractional Flow Reserve to invasive Fractional Flow Reserve in Diagnosis of Functional Coronary Stenosis: A Meta-Analysis. ( 27969867 )
2016
49
Reactive Myocardial Hyperemia for Functional Assessment of Coronary Stenosis Severity. ( 27993753 )
2016
50
Brief Report: Intestinal Microbiota-Produced Trimethylamine-N-Oxide and Its Association With Coronary Stenosis and HIV Serostatus. ( 26825179 )
2016

Variations for Coronary Stenosis

Expression for Coronary Stenosis

Search GEO for disease gene expression data for Coronary Stenosis.

Pathways for Coronary Stenosis

Pathways related to Coronary Stenosis according to GeneCards Suite gene sharing:

(show all 17)
id Super pathways Score Top Affiliating Genes
1 11.87 ALB IL6 TNNI3
2 11.86 ICAM1 SERPINE1 TLR4
3 11.79 ICAM1 IL6 TLR4
4 11.7 ICAM1 IL6 SERPINE1
5 11.68 IL6 SERPINE1 TLR4
6 11.65 ALB APOA1 APOE TNNI3
7
Show member pathways
11.64 ICAM1 IL6 TLR4
8
Show member pathways
11.64 ALB APOA1 APOB APOE CETP PCSK9
9 11.61 ICAM1 IL6 TLR4
10 11.48 ICAM1 IL6 TLR4
11
Show member pathways
11.47 ALB APOA1 APOB APOE
12 11.3 ICAM1 IL6 TLR4
13 11.26 APOB ICAM1 IL6
14 11.09 APOA1 ICAM1 IL6
15
Show member pathways
11.09 APOA1 APOB APOE CETP
16 11.04 ACE APOE TLR4
17 10.83 CRP IL6

GO Terms for Coronary Stenosis

Cellular components related to Coronary Stenosis according to GeneCards Suite gene sharing:

(show all 16)
id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.9 ACE ALB APOA1 APOB APOE CETP
2 external side of plasma membrane GO:0009897 9.85 ACE ICAM1 IL6 TLR4
3 early endosome GO:0005769 9.84 APOA1 APOB APOE PCSK9
4 blood microparticle GO:0072562 9.81 ALB APOA1 APOE PON1
5 endoplasmic reticulum lumen GO:0005788 9.8 ALB APOA1 APOB APOE IL6 PCSK9
6 very-low-density lipoprotein particle GO:0034361 9.63 APOA1 APOB APOE
7 endocytic vesicle lumen GO:0071682 9.61 APOA1 APOB APOE
8 low-density lipoprotein particle GO:0034362 9.58 APOA1 APOB APOE
9 extracellular matrix GO:0031012 9.56 APOE SERPINE1
10 chylomicron GO:0042627 9.54 APOA1 APOB APOE
11 spherical high-density lipoprotein particle GO:0034366 9.52 APOA1 PON1
12 intermediate-density lipoprotein particle GO:0034363 9.43 APOA1 APOB APOE
13 extracellular space GO:0005615 9.4 ACE ALB APOA1 APOB APOE CETP
14 high-density lipoprotein particle GO:0034364 9.26 APOA1 APOE CETP PON1
15 discoidal high-density lipoprotein particle GO:0034365 9.19 APOA1
16 extracellular exosome GO:0070062 10.18 ACE ALB APOA1 APOB APOE CETP

Biological processes related to Coronary Stenosis according to GeneCards Suite gene sharing:

(show top 50) (show all 52)
id Name GO ID Score Top Affiliating Genes
1 post-translational protein modification GO:0043687 9.95 ALB APOA1 APOB APOE IL6 PCSK9
2 receptor-mediated endocytosis GO:0006898 9.92 ALB APOA1 APOB APOE
3 response to lipopolysaccharide GO:0032496 9.92 APOB ICAM1 IL6 TLR4
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.89 ICAM1 IL6 TLR4
5 cellular response to lipopolysaccharide GO:0071222 9.89 ICAM1 IL6 SERPINE1 TLR4
6 platelet degranulation GO:0002576 9.88 ALB APOA1 SERPINE1
7 cellular response to tumor necrosis factor GO:0071356 9.88 APOB ICAM1 IL6
8 lipid transport GO:0006869 9.88 APOA1 APOB APOE CETP
9 defense response to Gram-negative bacterium GO:0050829 9.85 IL6 SERPINE1 TLR4
10 retinoid metabolic process GO:0001523 9.81 APOA1 APOB APOE
11 cellular protein metabolic process GO:0044267 9.8 ALB APOA1 APOB APOE IL6 PCSK9
12 positive regulation of nitric oxide biosynthetic process GO:0045429 9.78 ICAM1 IL6 TLR4
13 triglyceride metabolic process GO:0006641 9.77 APOE CETP PCSK9
14 steroid metabolic process GO:0008202 9.77 APOA1 APOB APOE CETP PCSK9
15 triglyceride homeostasis GO:0070328 9.74 APOA1 APOE CETP
16 triglyceride catabolic process GO:0019433 9.73 APOA1 APOB APOE
17 cholesterol transport GO:0030301 9.72 APOA1 APOB CETP
18 cholesterol efflux GO:0033344 9.71 APOA1 APOB APOE
19 positive regulation of chemokine production GO:0032722 9.7 IL6 TLR4
20 heart contraction GO:0060047 9.7 ACE TNNI3
21 positive regulation of cholesterol efflux GO:0010875 9.7 APOE PON1
22 negative regulation of macrophage derived foam cell differentiation GO:0010745 9.7 CETP CRP
23 high-density lipoprotein particle assembly GO:0034380 9.69 APOA1 APOE
24 negative regulation of blood coagulation GO:0030195 9.69 APOE SERPINE1
25 phospholipid efflux GO:0033700 9.69 APOA1 APOE
26 reverse cholesterol transport GO:0043691 9.69 APOA1 APOE CETP
27 phosphatidylcholine metabolic process GO:0046470 9.68 CETP PON1
28 cellular response to nutrient levels GO:0031669 9.68 ICAM1 IL6
29 regulation of receptor activity GO:0010469 9.68 PCSK9 SERPINE1
30 neutrophil mediated immunity GO:0002446 9.68 ACE IL6
31 phospholipid homeostasis GO:0055091 9.67 APOA1 CETP
32 negative regulation of lipid storage GO:0010888 9.67 CRP IL6
33 low-density lipoprotein particle remodeling GO:0034374 9.67 APOB APOE CETP
34 positive regulation of cholesterol esterification GO:0010873 9.66 APOA1 APOE
35 high-density lipoprotein particle clearance GO:0034384 9.66 APOA1 APOE
36 chylomicron remnant clearance GO:0034382 9.65 APOB APOE
37 neuron projection regeneration GO:0031102 9.65 APOA1 APOE
38 regulation of Cdc42 protein signal transduction GO:0032489 9.65 APOA1 APOE
39 very-low-density lipoprotein particle remodeling GO:0034372 9.64 APOE CETP
40 receptor-mediated virion attachment to host cell GO:0046813 9.63 ACE ICAM1
41 very-low-density lipoprotein particle clearance GO:0034447 9.63 APOB APOE
42 chylomicron assembly GO:0034378 9.63 APOA1 APOB APOE
43 lipoprotein catabolic process GO:0042159 9.61 APOB APOE
44 chylomicron remodeling GO:0034371 9.61 APOA1 APOB APOE
45 positive regulation of low-density lipoprotein particle receptor catabolic process GO:0032805 9.58 APOE PCSK9
46 lipoprotein biosynthetic process GO:0042158 9.58 APOA1 APOB APOE
47 lipoprotein metabolic process GO:0042157 9.56 APOA1 APOB APOE PCSK9
48 cholesterol homeostasis GO:0042632 9.55 APOA1 APOB APOE CETP PCSK9
49 high-density lipoprotein particle remodeling GO:0034375 9.26 ALB APOA1 APOE CETP
50 cholesterol metabolic process GO:0008203 9.1 APOA1 APOB APOE CETP PCSK9 PON1

Molecular functions related to Coronary Stenosis according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 lipid binding GO:0008289 9.72 ALB APOA1 APOB APOE CETP
2 cholesterol binding GO:0015485 9.58 APOA1 APOE CETP
3 phospholipid binding GO:0005543 9.56 APOA1 APOB APOE PON1
4 phospholipid transporter activity GO:0005548 9.51 APOA1 CETP
5 low-density lipoprotein particle binding GO:0030169 9.49 CRP PCSK9
6 lipoprotein particle binding GO:0071813 9.48 APOA1 APOE
7 phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 9.46 APOA1 APOE
8 lipid transporter activity GO:0005319 9.46 APOA1 APOB APOE CETP
9 very-low-density lipoprotein particle receptor binding GO:0070326 9.43 APOE PCSK9
10 apolipoprotein receptor binding GO:0034190 9.37 APOA1 PCSK9
11 low-density lipoprotein particle receptor binding GO:0050750 9.26 APOB APOE CRP PCSK9
12 cholesterol transporter activity GO:0017127 8.92 APOA1 APOB APOE CETP

Sources for Coronary Stenosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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