Aliases & Classifications for Cortical Blindness

MalaCards integrated aliases for Cortical Blindness:

Name: Cortical Blindness 12 14
Blindness, Cortical 41 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11831
ICD10 32 H47.61
ICD9CM 34 377.75
MeSH 41 D019575
NCIt 46 C118707
SNOMED-CT 64 68574006
UMLS 69 C0155320

Summaries for Cortical Blindness

MalaCards based summary : Cortical Blindness, also known as blindness, cortical, is related to mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes and epilepsy, and has symptoms including amaurosis fugax An important gene associated with Cortical Blindness is DOCK7 (Dedicator Of Cytokinesis 7). Affiliated tissues include brain, eye and cortex.

Wikipedia : 72 Cortical blindness is the total or partial loss of vision in a normal-appearing eye caused by damage to... more...

Related Diseases for Cortical Blindness

Diseases related to Cortical Blindness via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)
# Related Disease Score Top Affiliating Genes
1 mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes 31.4 MT-ND4 MT-ND6 POLG
2 epilepsy 28.7 ALDH7A1 IER3IP1 POLG
3 neuropathy 28.6 MT-ND4 MT-ND6 POLG
4 seizures, cortical blindness, and microcephaly syndrome 12.4
5 cortical blindness-intellectual disability-polydactyly syndrome 12.2
6 cortical blindness, retardation, and postaxial polydactyly 12.1
7 epileptic encephalopathy, early infantile, 23 11.6
8 anton's syndrome 11.3
9 mitochondrial dna depletion syndrome 4a 11.0
10 adrenoleukodystrophy 10.8
11 mohr-tranebjaerg syndrome 10.8
12 salt and pepper developmental regression syndrome 10.8
13 neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal dominant 10.8
14 epileptic encephalopathy, infantile or early childhood, 2 10.8
15 visual agnosia 10.8
16 cerebritis 10.2
17 encephalopathy 10.2
18 eclampsia 10.1
19 meningitis 10.0
20 leber optic atrophy and dystonia 10.0 MT-ND4 MT-ND6
21 leber optic atrophy 9.9 MT-ND4 MT-ND6
22 mitochondrial dna-associated leigh syndrome and narp 9.9 MT-ND4 MT-ND6
23 3-methylglutaconic aciduria, type v 9.9 MT-ND4 POLG
24 encephalomyopathy 9.9 MT-ND4 MT-ND6
25 glomerulonephritis 9.9
26 cardiac arrest 9.9
27 pre-eclampsia 9.9
28 visual pathway disease 9.9 DOCK7 IER3IP1 TIMM8A
29 visual cortex disease 9.9 DOCK7 IER3IP1 TIMM8A
30 ataxia and polyneuropathy, adult-onset 9.8
31 hydrocephalus 9.8
32 anosognosia 9.8
33 endocarditis 9.8
34 cervicitis 9.8
35 influenza 9.8
36 hypoglycemia 9.8
37 aneurysm 9.8
38 optic nerve disease 9.8 MT-ND4 MT-ND6
39 porphyria, acute intermittent 9.8
40 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 9.8
41 panencephalitis, subacute sclerosing 9.8
42 stroke, ischemic 9.8
43 hepatitis 9.8
44 thrombosis 9.8
45 dementia 9.8
46 hellp syndrome 9.8
47 porphyria 9.8
48 hepatic encephalopathy 9.8
49 status epilepticus 9.8
50 head injury 9.8

Comorbidity relations with Cortical Blindness via Phenotypic Disease Network (PDN):


Acute Cystitis Familial Atrial Fibrillation
Hypertension, Essential Intracranial Embolism

Graphical network of the top 20 diseases related to Cortical Blindness:



Diseases related to Cortical Blindness

Symptoms & Phenotypes for Cortical Blindness

UMLS symptoms related to Cortical Blindness:


amaurosis fugax

Drugs & Therapeutics for Cortical Blindness

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Intraocular Pressure During Prone Spinal Surgery Terminated NCT00176722 Phase 2
2 Determine the Effect of Intraocular Pressure (IOP), Optic Nerve Imaging, Venous Congestion in Volunteers Prone Position 5 Hours Completed NCT00875043

Search NIH Clinical Center for Cortical Blindness

Cochrane evidence based reviews: blindness, cortical

Genetic Tests for Cortical Blindness

Anatomical Context for Cortical Blindness

MalaCards organs/tissues related to Cortical Blindness:

38
Brain, Eye, Cortex, Liver, Heart, Bone, Occipital Lobe

Publications for Cortical Blindness

Articles related to Cortical Blindness:

(show top 50) (show all 417)
# Title Authors Year
1
Transient cortical blindness following gadolinium contrast. ( 29437876 )
2018
2
Transient cortical blindness following intracardiac repair of congenital heart disease in an 11-year-old boy. ( 28393793 )
2017
3
Cortical blindness as severe neuro-ophthalmological manifestation of tuberous sclerosis complex. ( 28435768 )
2017
4
Freiburg Neuropathology Case Conference : Widespread White Matter Lesions in aA Patient with Progressive Paraparesis and Cortical Blindness. ( 28477181 )
2017
5
(Almost) Lost at SEA: An Unusual Cause of Cortical Blindness. ( 28436816 )
2017
6
From Cortical Blindness to Conscious Visual Perception: Theories on Neuronal Networks and Visual Training Strategies. ( 28912694 )
2017
7
Cortical blindness as a rare presentation of hemorrhagic cerebral hyperperfusion syndrome following vertebral angioplasty. ( 29084739 )
2017
8
Cortical Blindness in a Child Secondary to Mycoplasma pneumoniae Infection. ( 27789154 )
2017
9
Cortical Blindness in Systemic Lupus Erythematosus: The Blind Wolf. ( 28937478 )
2017
10
Visual and Motor Recovery After "Cognitive Therapeutic Exercises" in Cortical Blindness: A Case Study. ( 28628550 )
2017
11
Cortical blindness and not optic neuritis as a cause of vision loss in a SjAPgren's syndrome (SS) patient with the neuromyelitis optica spectrum disorder (NMOSD): Challenges of ascribing demyelinating syndromes to SS: a case report. ( 28834867 )
2017
12
A Case Report of Transient Cortical Blindness After Angiography. ( 28471896 )
2017
13
Delayed Transient Cortical Blindness from Hypoxic Ischemic Encephalopathy. ( 28390792 )
2017
14
Delayed-onset Reversible Cortical Blindness after Resuscitation from Cardiac Arrest. ( 28936091 )
2017
15
Cortical blindness secondary to posterior reversible encephalopathy syndrome, recovered by successful blood pressure management. ( 29160546 )
2017
16
Patient With Severe Moyamoya Disease Who Presents With Acute Cortical Blindness. ( 28411258 )
2017
17
Case Report of Vestibularly evoked Visual Hallucinations in a Patient with Cortical Blindness. ( 27246956 )
2016
18
Residual perception of biological motion in cortical blindness. ( 27851900 )
2016
19
Post-traumatic transient cortical blindness in a child with occipital bone fracture. ( 27707613 )
2016
20
Cortical blindness along with motor aphasia: An unusual presentation of fat embolism syndrome. ( 28018064 )
2016
21
Transient cortical blindness and amnesia after cerebral angiography. ( 26755011 )
2016
22
Cortical blindness post coronary angiogram: A rare but frightening complication. ( 27490944 )
2016
23
Contrast-associated transient cortical blindness: three cases with MRI and electrophysiology findings. ( 27670442 )
2016
24
Relearning to See in Cortical Blindness. ( 26659828 )
2016
25
Transient cortical blindness after intradiscal oxygen-ozone therapy. ( 28112142 )
2016
26
Cortical Blindness After Cardiac Surgery: Just an Ischemic Mechanism? ( 26746795 )
2015
27
Mutations in DOCK7 in individuals with epileptic encephalopathy and cortical blindness. ( 26531641 )
2015
28
Acute cortical blindness caused by pre-eclampsia in the antepartum; posterior reversible encephalopathy syndrome (PRES). ( 26124823 )
2015
29
A Rare Hydrocephalus Complication: Cortical Blindness. ( 27411424 )
2015
30
Visual recovery in cortical blindness is limited by high internal noise. ( 26389544 )
2015
31
Teaching neuroImages: cortical blindness following acute obstructive hydrocephalus by a colloid cyst. ( 25666637 )
2015
32
Looming sensitive cortical regions without V1 input: evidence from a patient with bilateral cortical blindness. ( 26557059 )
2015
33
A case of transient cortical blindness associated with hypercapnia as a result of extremely enlarged adenoid tissue. ( 25606839 )
2015
34
Late onset reversible cortical blindness following electrocution. ( 26571457 )
2015
35
Transient cortical blindness following vertebral angiography: a case report. ( 25763297 )
2015
36
Contrast media induced transient cortical blindness. ( 26101228 )
2015
37
Anti-NMDA-receptor antibody-mediated cortical blindness: a case report. ( 26319702 )
2015
38
Methomyl poisoning presenting with decorticate posture and cortical blindness. ( 24744847 )
2014
39
Transient cortical blindness: a benign but devastating complication after coronary angiography and graft study. ( 25823165 )
2014
40
Ornithine Transcarbamylase Deficiency Presenting With Acute Reversible Cortical Blindness. ( 24850570 )
2014
41
Mutations in DOCK7 in individuals with epileptic encephalopathy and cortical blindness. ( 24814191 )
2014
42
Schizophrenia and cortical blindness: protective effects and implications for language. ( 25506321 )
2014
43
Visual imagery influences brain responses to visual stimulation in bilateral cortical blindness. ( 25571770 )
2014
44
Cortical blindness following posterior lumbar decompression and fusion. ( 23791834 )
2014
45
The coupling of vision with locomotion in cortical blindness. ( 24832646 )
2014
46
Recurrent bilateral occipital infarct with cortical blindness and anton syndrome. ( 24744933 )
2014
47
Gestational intestinal obstruction complicated by cortical blindness - a multidisciplinary case report. ( 25057408 )
2014
48
Amygdala activation for eye contact despite complete cortical blindness. ( 23785160 )
2013
49
Subacute Sclerosing Panencephalitis Case Presenting with Cortical Blindness: Early Diagnosis with MRI and MR Spectroscopya8c ( 23652857 )
2013
50
Meningioangiomatosis: a rare presentation with progressive cortical blindness. ( 23897877 )
2013

Variations for Cortical Blindness

Expression for Cortical Blindness

Search GEO for disease gene expression data for Cortical Blindness.

Pathways for Cortical Blindness

GO Terms for Cortical Blindness

Cellular components related to Cortical Blindness according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial inner membrane GO:0005743 9.33 MT-ND4 MT-ND6 TIMM8A
2 mitochondrion GO:0005739 9.02 ALDH7A1 MT-ND4 MT-ND6 POLG TIMM8A
3 respiratory chain GO:0070469 8.96 MT-ND4 MT-ND6

Biological processes related to Cortical Blindness according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial respiratory chain complex I assembly GO:0032981 9.16 MT-ND4 MT-ND6
2 mitochondrial electron transport, NADH to ubiquinone GO:0006120 8.96 MT-ND4 MT-ND6
3 response to nicotine GO:0035094 8.62 MT-ND4 MT-ND6

Molecular functions related to Cortical Blindness according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NADH dehydrogenase (ubiquinone) activity GO:0008137 8.62 MT-ND4 MT-ND6

Sources for Cortical Blindness

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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