Aliases & Classifications for Cortical Blindness

Aliases & Descriptions for Cortical Blindness:

Name: Cortical Blindness 12 14
Blindness, Cortical 42 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11831
ICD10 33 H47.61
ICD9CM 35 377.75
MeSH 42 D019575
NCIt 47 C118707
SNOMED-CT 64 68574006
UMLS 69 C0155320

Summaries for Cortical Blindness

MalaCards based summary : Cortical Blindness, also known as blindness, cortical, is related to cortical blindness, retardation, and postaxial polydactyly and progressive microcephaly-seizures-cortical blindness-developmental delay syndrome, and has symptoms including amaurosis fugax An important gene associated with Cortical Blindness is DOCK7 (Dedicator Of Cytokinesis 7). The drugs Epinephrine and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and cortex.

Wikipedia : 71 Cortical blindness is the total or partial loss of vision in a normal-appearing eye caused by damage to... more...

Related Diseases for Cortical Blindness

Diseases related to Cortical Blindness via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 124)
id Related Disease Score Top Affiliating Genes
1 cortical blindness, retardation, and postaxial polydactyly 11.9
2 progressive microcephaly-seizures-cortical blindness-developmental delay syndrome 11.9
3 cortical blindness mental retardation polydactyly 11.9
4 epileptic encephalopathy, early infantile, 23 11.5
5 anton's syndrome 11.2
6 mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes 10.9
7 mitochondrial dna depletion syndrome 4a 10.9
8 visual agnosia 10.7
9 amish infantile epilepsy syndrome 10.7
10 mohr-tranebjaerg syndrome 10.7
11 adrenoleukodystrophy 10.7
12 cerebritis 10.1
13 encephalopathy 10.1
14 eclampsia 10.0
15 fibroblastic liposarcoma 9.9 DOCK7 IER3IP1 TIMM8A
16 urinary schistosomiasis 9.9 DOCK7 IER3IP1 TIMM8A
17 meningitis 9.9
18 enteropathica 9.9 MT-CO3 MT-ND1
19 mucinous intrahepatic cholangiocarcinoma 9.9 POLG TIMM8A
20 mononeuritis multiplex 9.9 ALDH7A1 IER3IP1 POLG
21 retromolar area cancer 9.8 MT-CO3 MT-ND1
22 ndp-related retinopathies 9.8 MT-CO3 MT-ND1
23 glomerulonephritis 9.8
24 pre-eclampsia 9.8
25 nerve fibre bundle defect 9.8 MT-ND1 POLG
26 alopecia, androgenetic, 2 9.8 MT-CO3 MT-ND1
27 cervicitis 9.8
28 aneurysm 9.8
29 anosognosia 9.8
30 influenza 9.8
31 ataxia 9.8
32 cardiac arrest 9.8
33 endocarditis 9.8
34 hydrocephalus 9.8
35 hypoglycemia 9.8
36 dementia 9.7
37 thrombosis 9.7
38 hellp syndrome 9.7
39 porphyria 9.7
40 head injury 9.7
41 hepatic encephalopathy 9.7
42 hepatitis 9.7
43 status epilepticus 9.7
44 epilepsy 9.7
45 myoclonic epilepsy associated with ragged-red fibers 9.7 MT-CO3 MT-ND1 POLG
46 mast cell neoplasm 9.7 MT-CO3 MT-ND1 POLG
47 moyamoya disease 9.6
48 infective endocarditis 9.6
49 quadriplegia 9.6
50 progressive multifocal leukoencephalopathy 9.6

Comorbidity relations with Cortical Blindness via Phenotypic Disease Network (PDN):


Acute Cystitis Familial Atrial Fibrillation
Hypertension, Essential Intracranial Embolism

Graphical network of the top 20 diseases related to Cortical Blindness:



Diseases related to Cortical Blindness

Symptoms & Phenotypes for Cortical Blindness

UMLS symptoms related to Cortical Blindness:


amaurosis fugax

Drugs & Therapeutics for Cortical Blindness

Drugs for Cortical Blindness (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 40)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
2
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
4
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 11103-57-4, 68-26-8 445354
5 Autonomic Agents Phase 4,Phase 1,Phase 2
6 Peripheral Nervous System Agents Phase 4,Phase 1,Phase 2
7 Antiemetics Phase 4
8 Anti-Inflammatory Agents Phase 4
9 Antineoplastic Agents, Hormonal Phase 4
10 Antioxidants Phase 4
11 Epinephryl borate Phase 4
12 Gastrointestinal Agents Phase 4
13 glucocorticoids Phase 4
14 Hormone Antagonists Phase 4
15 Hormones Phase 4
16 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
17 Methylprednisolone acetate Phase 4
18 Methylprednisolone Hemisuccinate Phase 4
19 Micronutrients Phase 4
20 Neuroprotective Agents Phase 4
21 Prednisolone acetate Phase 4
22 Prednisolone hemisuccinate Phase 4
23 Prednisolone phosphate Phase 4
24 Protective Agents Phase 4
25 Racepinephrine Phase 4
26 Retinol palmitate Phase 4
27 Trace Elements Phase 4
28 Vitamins Phase 4
29 retinol Nutraceutical Phase 4
30
Ephedrine Approved Phase 1, Phase 2 299-42-3 9294
31
Pseudoephedrine Approved Phase 1, Phase 2 90-82-4 7028
32 Nasal Decongestants Phase 1, Phase 2
33 Ophthalmic Solutions Phase 1, Phase 2
34 Pharmaceutical Solutions Phase 1, Phase 2
35 Respiratory System Agents Phase 1, Phase 2
36 Tetrahydrozoline Phase 1, Phase 2
37 Vasoconstrictor Agents Phase 1, Phase 2
38
Menthol Approved 2216-51-5 16666
39
Amphetamine Approved, Illicit 300-62-9 5826 3007
40 Anti-Infective Agents, Local

Interventional clinical trials:

(show all 23)
id Name Status NCT ID Phase
1 Adrenal Cortical Function and Vitamin A Deficiency in Sepsis Completed NCT03152474 Phase 4
2 Paraorbital-Occipital Alternating Current Stimulation Therapy of Patients With Post-Chiasmatic Lesions Unknown status NCT01418820 Phase 2, Phase 3
3 Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion. Unknown status NCT02300818 Phase 1, Phase 2
4 Combined tDCS and Vision Restoration Training in Subacute Stroke Rehabilitation: A Pilot Study Completed NCT02935413 Phase 1, Phase 2
5 Combined tDCS and Vision Restoration Training in Post-acute Stroke: an Exploratory Efficacy and Safety Study Completed NCT02703870 Phase 1, Phase 2
6 Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging Recruiting NCT01864317 Phase 2
7 Intraocular Pressure During Prone Spinal Surgery Terminated NCT00176722 Phase 2
8 Neuroplasticity in Blind Subjects After Repetitive Tactile Stimulation Unknown status NCT01754103
9 Posterior Macular Adhesion: A Potential Risk Factor for Non-exudative Age Related Macular Degeneration (AMD) to Develop Exudative AMD Unknown status NCT00926861
10 Determine the Effect of Intraocular Pressure (IOP), Optic Nerve Imaging, Venous Congestion in Volunteers Prone Position 5 Hours Completed NCT00875043
11 The Connection Between Areas in the Brain of Blind Patients Completed NCT00001926
12 Study of Brain Changes Shaped by Experience Completed NCT00006424
13 GABA Levels in the Brains of Blind People Completed NCT00357409
14 Brain Plasticity of Verbal Memory in the Blind Completed NCT00059189
15 The Use of Transcranial Direct Current Stimulation (TDCS) to Enhance the Rehabilitative Effect of Vision Restoration Therapy Completed NCT00921427 Early Phase 1
16 Observational Study to Evaluate Allogeneic HSCT Outcomes for Cerebral Adrenoleukodystrophy (CALD) Recruiting NCT02204904
17 Feasibility of Stimulating the Visual Cortex in Blind Recruiting NCT02747589
18 Development of a Cortical Visual Neuroprosthesis for the Blind Recruiting NCT02983370
19 Functional Neuroimaging of Cortical Plasticity in the Human Visual System Recruiting NCT01062672
20 A Study to Evaluate the BrainPort Vision Device in Individuals Blinded by Traumatic Injury Active, not recruiting NCT02393118
21 Effects of Transcranial Direct Current Stimulation With Proprioceptive Training in Blind People Not yet recruiting NCT03173105
22 Non-invasive Brain Stimulation for Pediatric ADHD Not yet recruiting NCT03104972
23 tDCS Associated to Blindsight Rehabilitation for the Treatment of Homonymous Hemianopsia Withdrawn NCT02956668

Search NIH Clinical Center for Cortical Blindness

Cochrane evidence based reviews: blindness, cortical

Genetic Tests for Cortical Blindness

Anatomical Context for Cortical Blindness

MalaCards organs/tissues related to Cortical Blindness:

39
Brain, Eye, Cortex, Liver, Heart, Bone, Occipital Lobe

Publications for Cortical Blindness

Articles related to Cortical Blindness:

(show top 50) (show all 402)
id Title Authors Year
1
Cortical Blindness in a Child Secondary to Mycoplasma pneumoniae Infection. ( 27789154 )
2017
2
Patient With Severe Moyamoya Disease Who Presents With Acute Cortical Blindness. ( 28411258 )
2017
3
Transient cortical blindness and amnesia after cerebral angiography. ( 26755011 )
2016
4
Cortical blindness post coronary angiogram: A rare but frightening complication. ( 27490944 )
2016
5
Relearning to See in Cortical Blindness. ( 26659828 )
2016
6
Cortical blindness along with motor aphasia: An unusual presentation of fat embolism syndrome. ( 28018064 )
2016
7
Contrast-associated transient cortical blindness: three cases with MRI and electrophysiology findings. ( 27670442 )
2016
8
Post-traumatic transient cortical blindness in a child with occipital bone fracture. ( 27707613 )
2016
9
Case Report of Vestibularly evoked Visual Hallucinations in a Patient with Cortical Blindness. ( 27246956 )
2016
10
Residual perception of biological motion in cortical blindness. ( 27851900 )
2016
11
Transient cortical blindness following vertebral angiography: a case report. ( 25763297 )
2015
12
Acute cortical blindness caused by pre-eclampsia in the antepartum; posterior reversible encephalopathy syndrome (PRES). ( 26124823 )
2015
13
Mutations in DOCK7 in individuals with epileptic encephalopathy and cortical blindness. ( 26531641 )
2015
14
Visual recovery in cortical blindness is limited by high internal noise. ( 26389544 )
2015
15
Looming sensitive cortical regions without V1 input: evidence from a patient with bilateral cortical blindness. ( 26557059 )
2015
16
A case of transient cortical blindness associated with hypercapnia as a result of extremely enlarged adenoid tissue. ( 25606839 )
2015
17
Contrast media induced transient cortical blindness. ( 26101228 )
2015
18
A Rare Hydrocephalus Complication: Cortical Blindness. ( 27411424 )
2015
19
Anti-NMDA-receptor antibody-mediated cortical blindness: a case report. ( 26319702 )
2015
20
Cortical Blindness After Cardiac Surgery: Just an Ischemic Mechanism? ( 26746795 )
2015
21
Teaching neuroImages: cortical blindness following acute obstructive hydrocephalus by a colloid cyst. ( 25666637 )
2015
22
Late onset reversible cortical blindness following electrocution. ( 26571457 )
2015
23
Schizophrenia and cortical blindness: protective effects and implications for language. ( 25506321 )
2014
24
Cortical blindness following posterior lumbar decompression and fusion. ( 23791834 )
2014
25
Methomyl poisoning presenting with decorticate posture and cortical blindness. ( 24744847 )
2014
26
Mutations in DOCK7 in individuals with epileptic encephalopathy and cortical blindness. ( 24814191 )
2014
27
The coupling of vision with locomotion in cortical blindness. ( 24832646 )
2014
28
Visual imagery influences brain responses to visual stimulation in bilateral cortical blindness. ( 25571770 )
2014
29
Recurrent bilateral occipital infarct with cortical blindness and anton syndrome. ( 24744933 )
2014
30
Gestational intestinal obstruction complicated by cortical blindness - a multidisciplinary case report. ( 25057408 )
2014
31
Transient cortical blindness: a benign but devastating complication after coronary angiography and graft study. ( 25823165 )
2014
32
Ornithine Transcarbamylase Deficiency Presenting With Acute Reversible Cortical Blindness. ( 24850570 )
2014
33
Amygdala activation for eye contact despite complete cortical blindness. ( 23785160 )
2013
34
Transient cortical blindness as a complication of posterior spinal surgery in a pediatric patient. ( 23407429 )
2013
35
Cortical blindness after complicated general anesthesia in urological surgery. ( 24116261 )
2013
36
Reversible cortical blindness and internuclear ophthalmoplegia after neurosurgical operation: case report and review of the literature. ( 23042139 )
2013
37
Contrast-induced transient cortical blindness. ( 22891710 )
2013
38
Cortical Blindness due to Bilateral Occipital Infarcts in a Renal Failure Patient with Prostate Cancer: A Rare Complication of Hemodialysis. ( 23424594 )
2013
39
Permanent cortical blindness after bronchial artery embolization. ( 23580115 )
2013
40
Cortical blindness in a patient with eclampsia: posterior reversible encephalopathy syndrome. ( 23571395 )
2013
41
Meningioangiomatosis: a rare presentation with progressive cortical blindness. ( 23897877 )
2013
42
Isolated cortical blindness without simultaneous neurological involvement in progressive multifocal leukoencephalopathy in a patient with human immune deficiency virus infection. ( 23514446 )
2013
43
Transient cortical blindness after coronary artery angiography. ( 24570699 )
2013
44
Cortical blindness and choroidal metastases secondary to metastatic breast carcinoma in a male patient. ( 23410813 )
2013
45
Cortical blindness in obstetric patients: Case report of two different presentations. ( 23959359 )
2013
46
Subacute Sclerosing Panencephalitis Case Presenting with Cortical Blindness: Early Diagnosis with MRI and MR Spectroscopya8c ( 23652857 )
2013
47
Dissociation between goal-directed and discrete response localization in a patient with bilateral cortical blindness. ( 23944840 )
2013
48
Transient cortical blindness after spinal surgery as initial presenting sign of hereditary thrombophilia. ( 23514658 )
2013
49
An unusual case of transient cortical blindness with sagittal sinus thrombosis in a case of Henoch-Schonlein purpura. ( 22864046 )
2012
50
Post-anesthetic cortical blindness in cats: twenty cases. ( 22381708 )
2012

Variations for Cortical Blindness

Expression for Cortical Blindness

Search GEO for disease gene expression data for Cortical Blindness.

Pathways for Cortical Blindness

GO Terms for Cortical Blindness

Cellular components related to Cortical Blindness according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 mitochondrial inner membrane GO:0005743 9.13 MT-CO3 MT-ND1 TIMM8A
2 mitochondrion GO:0005739 9.02 ALDH7A1 MT-CO3 MT-ND1 POLG TIMM8A

Biological processes related to Cortical Blindness according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 sensory perception of sound GO:0007605 8.62 ALDH7A1 DIAPH1

Sources for Cortical Blindness

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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