MCID: CRT012
MIFTS: 44

Cortical Blindness malady

Eye diseases category
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Summaries for Cortical Blindness

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Wikipedia:65 Cortical blindness is the total or partial loss of vision in a normal-appearing eye caused by damage to... more...

MalaCards based summary: Cortical Blindness, also known as blindness, cortical, is related to antiphospholipid syndrome and thrombophilia. An important gene associated with Cortical Blindness is IFNA10 (interferon, alpha 10), and among its related pathways are Histidine metabolism and Complement and coagulation cascades. The compounds mnpt and aprosulate have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and cortex, and related mouse phenotype normal.

Aliases & Classifications for Cortical Blindness

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Cortical Blindness, Aliases & Descriptions:

Name: Cortical Blindness 8 10
 
Blindness, Cortical 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


External Ids:

Disease Ontology8 DOID:11831
ICD9CM27 377.75
SNOMED-CT57 68574006
MeSH34 D019575

Related Diseases for Cortical Blindness

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Graphical network of the top 20 diseases related to Cortical Blindness:



Diseases related to cortical blindness

Symptoms for Cortical Blindness

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Drugs & Therapeutics for Cortical Blindness

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Drug clinical trials:

Search ClinicalTrials for Cortical Blindness

Search NIH Clinical Center for Cortical Blindness

Genetic Tests for Cortical Blindness

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Anatomical Context for Cortical Blindness

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MalaCards organs/tissues related to Cortical Blindness:

32
Eye, Brain, Cortex, Liver, Heart, Occipital lobe, Bone marrow, Bone, Testes, Spinal cord, Skeletal muscle, Kidney, Lung, Breast, Placenta, Prostate, Endothelial, Amygdala

Animal Models for Cortical Blindness or affiliated genes

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MGI Mouse Phenotypes related to Cortical Blindness:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.1ALDH7A1, F3, ISL2, F2

Publications for Cortical Blindness

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Articles related to Cortical Blindness:

(show top 50)    (show all 374)
idTitleAuthorsYear
1
Cortical Blindness due to Bilateral Occipital Infarcts in a Renal Failure Patient with Prostate Cancer: A Rare Complication of Hemodialysis. (23424594)
2013
2
Isolated cortical blindness without simultaneous neurological involvement in progressive multifocal leukoencephalopathy in a patient with human immune deficiency virus infection. (23514446)
2013
3
Transient cortical blindness as a complication of posterior spinal surgery in a pediatric patient. (23407429)
2013
4
Cortical blindness in a child with acute glomerulonephritis. (23436964)
2012
5
Cortical blindness and posterior reversible encephalopathy syndrome in an older patient. (22669215)
2012
6
Transient cortical blindness following a Hangman's fracture: a case report and review of literature. (22026474)
2012
7
Transient cortical blindness after coronary angiography: a case report and literature review. (21465952)
2011
8
Transient cortical blindness post angiography--a case report. (22224355)
2011
9
Cortical blindness due to sagittal sinus thrombosis in acute lymphoblastic leukaemia. (19006563)
2009
10
Pyridoxine-dependent epilepsy: normal outcome in a patient with late diagnosis after prolonged status epilepticus causing cortical blindness. (19294602)
2008
11
Sudden cortical blindness in an adult with moyamoya disease. (17320646)
2007
12
An unusual but dramatic complication of coronary angiography: transient cortical blindness. (17692963)
2007
13
Visual restoration in cortical blindness: insights from natural and TMS-induced blindsight. (16864478)
2006
14
MR imaging findings of cortical blindness following cerebral angiography: is this entity related to posterior reversible leukoencephalopathy? (15661726)
2005
15
Repetitive visual stimulation: a neuropsychological approach to the treatment of cortical blindness. (14530588)
2003
16
Diffusion-weighted magnetic resonance imaging and the evaluation of cortical blindness in preeclampsia. (14609710)
2003
17
Cortical blindness and neurologic injury complicating cervical transforaminal injection for cervical radiculopathy. (12883429)
2003
18
Parietal contusion and transient superior sagittal sinus occlusion presenting with cortical blindness. (12435960)
2002
19
Visual hallucinations in recovery from cortical blindness: imaging correlates. (10768632)
2000
20
Cortical blindness as a manifestation of hypomagnesemia secondary to cisplatin therapy: case report and review of literature. (9889044)
1999
21
Cortical blindness in acute intermittent porphyria. (10778597)
1999
22
Transient cortical blindness in preeclampsia with indication of generalized vascular endothelial damage. (9736196)
1998
23
Obstetrical anaesthesia for a parturient with preeclampsia, HELLP syndrome and acute cortical blindness. (9598260)
1998
24
Transient bilateral cortical blindness due to hypoxemia. (8669642)
1996
25
Cortical blindness and visual imagery. (8848191)
1995
26
Cortical blindness during left internal mammary angiography. (8749871)
1995
27
Confusion, cortical blindness and fever. (7776914)
1995
28
Transient cortical blindness after second coronary angiography: is immunological mechanism possible? (8149434)
1994
29
Transient cortical blindness due to hypertensive encephalopathy. Magnetic resonance imaging correlation. (8501259)
1993
30
Interferon-related cortical blindness. (1537083)
1992
31
Cortical blindness--a catastrophic side effect of vincristine. (1421432)
1992
32
Cortical blindness and residual vision: is the "second" visual system in humans capable of more than rudimentary visual perception? (2046931)
1991
33
VEP and EEG in cortical blindness: a case with a complicated course. (2081688)
1990
34
Cortical blindness due to osmotic disruption of the blood-brain barrier by angiographic contrast material: CT and MRI studies. (2927682)
1989
35
Anton syndrome and cortical blindness due to bilateral occipital infarction. (2638312)
1989
36
MR imaging of postpartum cortical blindness. (2745774)
1989
37
Cortical blindness after subclavian vein catheterization. (3184426)
1988
38
Cyclosporin A-induced reversible cortical blindness. (2977135)
1988
39
Nonspecific dementia, cortical blindness, and Congophilic angiopathy. A clinicopathological report. (3819782)
1987
40
Transient postictal cortical blindness. (2958507)
1987
41
Cortical blindness in infancy. (3726955)
1986
42
Hydrocephalus and transient cortical blindness. (6507566)
1984
43
Cortical blindness following cardiac arrest. (7184932)
1982
44
Isolated cortical blindness in pregnancy. (7179953)
1982
45
Transient cortical blindness in hepatic encephalopathy. (521266)
1979
46
Quadriplegia and cortical blindness in Hemophilus influenzae meningitis. (671161)
1978
47
Visual evoked responses in childhood cortical blindness after head trauma and meningitis. A longitudinal study of six cases. (4472425)
1974
48
The aetiology of cortical blindness in Nigeria. (5521690)
1970
49
Electrophysiological findings in cortical blindness. Report of a case. (4160394)
1966
50
Extradural haemorrhage as a cause of cortical blindness. (18124752)
1949

Variations for Cortical Blindness

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Expression for genes affiliated with Cortical Blindness

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Expression patterns in normal tissues for genes affiliated with Cortical Blindness

Search GEO for disease gene expression data for Cortical Blindness.

Pathways for genes affiliated with Cortical Blindness

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Pathways related to Cortical Blindness according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
histamine biosynthesis37
9.7ALDH7A1, HNMT
2
Show member pathways
Complement Activation, Classical Pathway37
Complement and Coagulation Cascades37
9.3F3, F2
3
Show member pathways
9.3F3, F2
4
Show member pathways
9.0IFNA10, F3, F2

Compounds for genes affiliated with Cortical Blindness

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Compounds related to Cortical Blindness according to GeneCards/GeneDecks:

(show top 50)    (show all 51)
idCompoundScoreTop Affiliating Genes
1mnpt449.8F3, F2
2aprosulate449.8F2, F3
3napsagatran449.8F2, F3
4brodifacoum449.8F2, F3
5certoparin449.8F2, F3
6appt449.8F2, F3
7hemochron449.8F2, F3
8heparin sodium449.8F2, F3
9inogatran449.8F2, F3
10ecarin449.8F3, F2
11dextran 70449.8F3, F2
12polybrene449.8F2, F3
13spectrozyme449.8F2, F3
14s-warfarin449.8F2, F3
15danaparoid449.7F2, F3
16hepaplastin449.7F2, F3
17rivaroxaban44 1110.7F2, F3
18kaolin449.7F2, F3
19ximelagatran44 1110.7F2, F3
20organon449.7F2, F3
21vitamin k144 2410.7F2, F3
22heparinoids449.7F2, F3
23fondaparinux449.7F3, F2
24acenocoumarol44 50 1111.7F2, F3
25bivalirudin44 1110.7F2, F3
26phenprocoumon44 50 1111.7F2, F3
27coumarins449.7F2, F3
28hydroxyethyl starch449.7F2, F3
29argatroban44 1110.7F2, F3
30ppack449.7F3, F2
31tranexamic acid44 1110.7F2, F3
32protamine sulfate449.7F2, F3
33tirofiban44 1110.7F3, F2
34epsilon aminocaproic acid449.6F3, F2
35ristocetin449.6F3, F2
36gamma-carboxyglutamic acid449.6F2, F3
37levonorgestrel44 61 28 1112.6F3, F2
38abciximab44 1110.6F2, F3
39coumarin44 2 50 2412.6F3, F2
40desmopressin44 61 28 1112.6F3, F2
41clopidogrel44 50 24 1112.5F2, F3
42cardiolipin44 1110.5F3, F2
43hirudin449.5F3, F2
44dipyridamole44 61 28 1112.4F2, F3
45protamine449.4F3, F2
46dermatan sulfate449.3F3, F2
47aprotinin44 1110.3F3, F2
48aspirin44 50 28 2412.2F2, F3, HNMT
49warfarin44 50 24 1112.2F2, F3
50kininogen449.0F3, F2

GO Terms for genes affiliated with Cortical Blindness

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Biological processes related to Cortical Blindness according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood coagulationGO:0075969.0IFNA10, F3, F2

Products for genes affiliated with Cortical Blindness

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  • Antibodies
  • Proteins
  • Lysates

Sources for Cortical Blindness

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet