MCID: CRT033
MIFTS: 40

Corticobasal Degeneration malady

Genetic diseases, Rare diseases, Neuronal diseases categories

Aliases & Classifications for Corticobasal Degeneration

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Sources:
45NIH Rare Diseases, 46NINDS, 51Orphanet, 65UMLS, 28ICD10 via Orphanet, 66UMLS via Orphanet
See all sources

Aliases & Descriptions for Corticobasal Degeneration:

Name: Corticobasal Degeneration 45 46 51 65
Cortical-Basal Ganglionic Degeneration 45
 
Cortico-Basal Ganglionic Degeneration 45
Cbgd 45


Classifications:



Characteristics (Orphanet epidemiological data):

51
corticobasal degeneration:
Age of onset: Adult


External Ids:

Orphanet51 278
ICD10 via Orphanet28 G31.0
UMLS via Orphanet66 C0393570

Summaries for Corticobasal Degeneration

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NINDS:46 Corticobasal degeneration is a progressive neurological disorder characterized by nerve cell loss and (shrinkage) of multiple areas of the brain including the cerebral cortex and the basal ganglia. Corticobasal degeneration progresses gradually. Initial symptoms, which typically begin at or around age 60, may first appear on one side of the body (unilateral), but eventually affect both sides as the disease progresses. Symptoms are similar to those found in Parkinson disease, such as poor coordination, (an absence of movements), (a resistance to imposed movement), (impaired balance); and limb (abnormal muscle postures). Other symptoms such as cognitive and visual-spatial impairments, apraxia (loss of the ability to make familiar, purposeful movements), hesitant and halting speech, (muscular jerks), and (difficulty swallowing) may also occur. An individual with corticobasal degeneration eventually becomes unable to walk.

MalaCards based summary: Corticobasal Degeneration, also known as cortical-basal ganglionic degeneration, is related to pick disease and parkinson disease 5. An important gene associated with Corticobasal Degeneration is MAPT (Microtubule-Associated Protein Tau). Affiliated tissues include cortex, brain and eye, and related mouse phenotypes are adipose tissue and skeleton.

NIH Rare Diseases:45 Corticobasal degeneration is characterized by the break down (degeneration) of parts of the brain, including the cerebral cortex and basal ganglia. the cerebral cortex is responsible for most of the brain's processing of information, and the basal ganglia are deep brain structures that help start and control movement. signs and symptoms of corticobasal degeneration include poor coordination, loss of movement, rigidity, poor balance, unnatural posturing of the muscles, intellectual (cognitive) impairment, speech impairment, muscular jerks, and difficulty swallowing. these symptoms develop and worsen over time. currently the cause of corticobasal degeneration is not known. last updated: 5/14/2015

Wikipedia:68 Corticobasal degeneration (CBD) or Corticobasal ganglionic degeneration (CBGD) is a rare, progressive... more...

Related Diseases for Corticobasal Degeneration

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Diseases in the Corticobasal Degeneration family:

Corticobasal Degeneration, Mapt-Related

Diseases related to Corticobasal Degeneration via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 98)
idRelated DiseaseScoreTop Affiliating Genes
1pick disease30.9MAPT, RPS27A, TARDBP
2parkinson disease 530.5MAPT, UCHL1
3supranuclear palsy, progressive atypical30.3MAPT, RPS27A
4parkinson disease, late-onset29.5GBA, MAPT, PITX3, RPS27A, UCHL1
5apraxia10.8
6dementia10.8
7cerebritis10.7
8aphasia10.7
9tauopathy10.7
10neuronitis10.6
11myoclonus10.6
12multiple system atrophy10.5
13alzheimer disease10.4
14supranuclear palsy, progressive10.4
15creutzfeldt-jakob disease10.4
16dystonia10.4
17popliteal pterygium syndrome 110.4
18dementia, frontotemporal10.4
19cerebral palsy10.4
20foster-kennedy syndrome10.4
21spiradenoma10.4
22basal ganglia disease10.4
23cerebral degeneration10.4
24cranial nerve disease10.4
25cranial nerve palsy10.4
26eye degenerative disease10.4
27eye disease10.4
28globe disease10.4
29movement disease10.4
30ocular motility disease10.4
31ophthalmoplegia10.4
32optic nerve disease10.4
33degenerative nerve diseases10.4
34neurologic diseases10.4
35motor neuro-ophthalmic disorders10.4
36semantic dementia10.4
37supranuclear ocular palsy10.4
38corticobasal degeneration, mapt-related10.4
39autosomal dominant popliteal pterygium syndrome10.4
40motor neuron disease10.3
41hemiparkinsonism-hemiatrophy syndrome10.3
42rem sleep behavior disorder10.3
43lateral sclerosis10.3
44basal ganglia calcification10.3
45nervous system disease10.3
46prion disease10.3
47encephalopathy10.3
48abri amyloidosis10.2MAPT, TARDBP
49carotid stenosis10.2MAPT, TARDBP
50neuropathy ataxia retinitis pigmentosa syndrome10.2MAPT, RPS27A

Graphical network of the top 20 diseases related to Corticobasal Degeneration:



Diseases related to corticobasal degeneration

Symptoms for Corticobasal Degeneration

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Drugs & Therapeutics for Corticobasal Degeneration

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Drugs for Corticobasal Degeneration (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1cadexomer iodinePhase 4425
2
IodinePhase 44597553-56-2807
Synonyms:
I2
Iode
Iodine-molecule
 
Iodio
Iodum
Jod
Jood
Tincture iodine
3CalamusNutraceuticalPhase 4312
4UbiquinonePhase 2, Phase 390
5
Coenzyme Q10NutraceuticalPhase 2, Phase 3101303-98-05281915
Synonyms:
(all-E)-2,3-dimethoxy-5-methyl-6-(3,7,11,15,19,23,27,31-octamethyl-2,6,10,14,18,22,26,30-dotriacontaoctaenyl)-2,5-Cyclohexadiene-1,4-dione
(all-E)-2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-2,5-Cyclohexadiene-1,4-dione
2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-p-Benzoquinone
2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl]-5,6-dimethoxy-3-methyl- 2,5-Cyclohexadiene-1,4-dione
4-Ethyl-5-fluoropyrimidine
Aqua Q 10L10
Aqua Q10
Bio-Quinon
Bio-Quinone Q10
CoQ10
Coenzyme Q10
Ensorb
Kaneka Q10
Kudesan
 
Li-Q-Sorb
Liquid-Q
Neuquinon
Neuquinone
PureSorb Q 40
Q 10AA
Q-Gel
Q-Gel 100
Ubidecarenone
Ubiquinone 10
Ubiquinone 50
Ubiquinone Q10
Ubiquinone-10
Unbiquinone
Unispheres Q 10
6
LithiumapprovedPhase 1, Phase 22067439-93-228486
Synonyms:
159577-72-7
201049_ALDRICH
207241_ALDRICH
207241_FLUKA
220914_ALDRICH
248827_ALDRICH
265969_ALDRICH
265977_ALDRICH
265985_ALDRICH
265993_ALDRICH
266000_ALDRICH
278327_ALDRICH
320080_ALDRICH
340421_ALDRICH
3Li
444456_ALDRICH
499811_ALDRICH
62500_FLUKA
64975-42-4
7439-93-2
7580-67-8
AB1003835
AC1MHL68
C15473
CHEBI:30145
CID3028194
D008094
D08133
EINECS 231-102-5
EINECS 231-484-3
Eskalith
HSD690000
HSDB 549
HSDB 647
HSDB 6900
Hydrure de lithium [French]
LITHIUM
LITHIUM HYDRIDE
 
LITHIUM HYDRIDE, 98.6%
LITHIUM ion
LS-88055
LS-88066
LTBB002851
Li
Li(+)
Li(+) cation
Li(+) ion
Lithium
Lithium Carbonate
Lithium [UN1415] [Dangerous when wet]
Lithium [UN1415] [Dangerous when wet]
Lithium atom
Lithium atomic absorption standard solution
Lithium carbonate
Lithium cation
Lithium compounds
Lithium element
Lithium hydride (LiH)
Lithium hydride [UN1414] [Dangerous when wet]
Lithium hydride [UN1414] [Dangerous when wet]
Lithium hydride, fused solid [UN2805] [Dangerous when wet]
Lithium hydride, fused solid [UN2805] [Dangerous when wet]
Lithium monohydride
Lithium, elemental
Lithium, ion
Lithium, ion (li1+)
Lithium, metallic
Lithium-6Li
LithoTab
Lithobid
MolPort-003-926-239
MolPort-003-927-072
Normothymin-E
Normothymin-E (TN)
UN1414
UN1415
UN2805
litio
7
QuinidineapprovedPhase 24156-54-2441074
Synonyms:
(+)-quinidine
(-)-Quinine
(8R,9S)-Quinidine
(R)-(6-Methoxyquinolin-4-yl)((3S,4R,7S)-3-vinylquinuclidin-7-yl)methanol
(S)-(6-Methoxy-quinolin-4-yl)-((2R,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol
(S)-(6-Methoxyquinolin-4-yl)((2R,5R)-5-vinylquinuclidin-2-yl)methanol
11010-73-4
12239-42-8
128544-03-6
130-89-2
130-95-0
1407-83-6
21480-31-9
22600_FLUKA
22620_FLUKA
22620_SIGMA
50-54-4
500225-45-6
549-56-4
55980-20-6
56-54-2
572-59-8
6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol
6119-70-6
6151-39-9
6151-40-2
6183-68-2
6591-63-5
6912-57-8
72646-90-3
767303-40-2
804-63-7
840482-04-4
845886-64-8
857212-53-4
864908-93-0
875538-34-4
882741-47-1
883881-01-4
888714-03-2
890027-24-4
894767-09-0
898813-59-7
898814-00-1
898814-28-3
899813-83-3
900786-66-5
900789-95-9
906550-97-8
909263-47-4
909767-48-2
909882-78-6
910878-25-0
910880-97-6
910899-51-3
911445-75-5
918778-04-8
AB00514657
AC1L199L
AC1L1ANE
AC1L1LHL
AC1L1R7Y
AC1L3RNZ
AC1L9AHT
AC1L9AHW
AC1LCUGN
AC1LDI43
AC1LDI46
AC1MBNAI
AC1MHDEF
AC1MHUCH
AC1MHWS7
AC1MI1Q5
AC1NSV55
AC1NSV58
AC1NSZYR
AC1NSZYU
AC1NUNML
AC1NUNMO
AC1NX8JM
AC1O56R7
AC1O7EE0
AC1O7GNZ
AC1OAH7Z
AC1OCD5W
AC1OCD62
AC1OFCPL
AC1Q4EZ5
AC1Q4EZ6
AC1Q58AF
AR-1A4833
AR-1H2065
Aflukin
Apo-Quinidine
Auriquin
BB_NC-0697
BIB1110
BIDD:GT0144
Biquin Durules
C06526
C06527
C20H24N2O2
CCRIS 5755
CCRIS 672
CHEBI:111177
CHEBI:15854
CHEBI:28593
CHEMBL170
CHEMBL21578
CHEMBL576997
CHEMBL601807
CHEMBL97
CID10448938
CID1065
CID25522
CID2728270
CID3000825
CID3032576
CID3034034
CID3036746
CID441073
CID441074
CID5317111
CID5317112
CID5320867
CID5320868
 
CID5484444
CID5484450
CID5748152
CID5953
CID637552
CID6453100
CID6602154
CID6604605
CID667448
CID667449
CID6857801
CID6916033
CID6916036
CID7048767
CID8549
CID94175
CID9967055
CIN-QUIN
CPD000857275
Cardioquin
Chinidin
Chinidine
Chinidinum
Chinin
Chinine
Cin-Quin
Coccinine
Coco-Quinine
Conchinin
Conchinine
Conquinine
D08458
D08460
DB00468
DB00908
Duraquin
Epiquinidine
FT-0082277
GNF-PF-5459
GNF-Pf-180
GNF-Pf-5423
HMS1304I22
HMS1607A11
HMS1989J09
HMS2089E05
HSDB 225
HSDB 2501
I14-3348
I14-3397
IBS-L0034250
IDI1_000134
KBio1_000134
KBio2_001392
KBio2_003960
KBio2_006528
KBio3_001551
KST-1A1085
Kinidin
Kinidin (TN)
L001278
LS-141252
LS-187236
LS-194958
LS-221
LS-4562
LT00645788
Lopac-Q-0875
Lopac-Q-1250
MLS001304041
MLS001335913
MLS001335914
NCI-C56246
NCI60_004320
NINDS_000134
NSC 192949
NSC 5362
NSC131458
NSC192949
NSC5362
NSC667852
Novoquinidin
OR28880
Pitayin
Pitayine
Q0006
Q3625_SIGMA
Quin-Release
Quinact
Quinaglute
Quinaglute Dura-Tabs
Quinalan
Quinate
Quinatime
Quindan
Quindine
Quinicardine
Quinidex
Quinidex Extentabs
Quinidina
Quinidine
Quinidine Gluconate
Quinidine Sulfate
Quiniduran
Quinimax
Quinine
Quinine Dab
Quinora
Quniacridine
RH01857
SAM002264644
SB01652
SMP1_000254
SMR000718748
SMR000857275
SPBio_001375
SPBio_002379
ST056282
TCMDC-131239
TNP00086
alpha-(6-Methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol
beta-Quinine
bmse000511
chinidinum
chininum
quinidina
quinidine
quinina
β-quinine
8
DextromethorphanapprovedPhase 2113125-71-35360696, 5362449
Synonyms:
( )-3-Methoxy-N-methylmorphinon
( )-cis-1,3,4,9,10,10a-Hexahydro-6-methoxy-11-methyl-2H-10,4alpha-iminoethanophenanthren
(+)-3-Methoxy-17-methylmorphinan
(-)-3-Methoxy-N-methylmorphinan
(9alpha,13alpha,14alpha)-17-methyl-3-(methyloxy)morphinan
125-69-9 (hydrobromide)
125-70-2
125-71-3
18046-32-7
18609-21-7 (hydrochloride)
3-Methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
3-Methoxy-17-methylmorphinan
32062-10-5
4-21-00-01367 (Beilstein Handbook Reference)
6700-34-1 (hydrobromide, mono-hydrate)
9alpha,13alpha,14alpha-Morphinan, 3-methoxy-17-methyl- (8CI)
AC-13098
AC1L1EYT
Albutussin
Antussan
BA 2666
BPBio1_000503
BRD-K33211335-337-03-7
BRN 0088549
BSPBio_000457
Balminil DM
Balminil DM Children
Bayer Select Flu Relief
Bayer Select Head & Chest Cold
Bayer Select Night Time Cold
Benylin Adult Formula Cough Suppressant
Benylin DM
Benylin DM (TN)
Benylin DM 12 Hour
Benylin DM for Children
Benylin DM for Children 12 Hour
Benylin Pediatric Cough Suppressant
C06947
CHEBI:128891
CHEBI:4470
CHEBI:580686
CHEMBL22207
CHEMBL52440
CID3008
CID5360696
CID5362449
Calmylin #1
Canfodion
Cerose-DM
Chloraseptic DM
Contac Day & Night Cold/Flu Day Caplets
Contac Jr. Non-drowsy Formula
Contac Nighttime Cold Medicine
Contac Severe Cold Formula Maximum Strength
Contac Severe Cold Formula Non-Drowsy
Coricidin Syrup
Cosylan
Cough Medicine soothing relief
Cough-X
Creo-Terpin
D-Methorphan
D-Methorphan Hydrobromide
D03742
DB00514
DEA No. 9210
DM
DMHM
DXM
Delsym
Delsym (dextromethorphan)
Delsym Cough Formula
Delta-Methorphan
Demorphan
Demorphan Hydrobromide
Demorphan hydrobromide
Demorphine
Destrometerfano
Destrometerfano [DCIT]
Destrometerfano [Dcit]
Dextromethorfan
Dextromethorfan [Czech]
Dextromethorphan
Dextromethorphan (USP)
Dextromethorphan Bromhydrate
Dextromethorphan Bromide
Dextromethorphan Hydrobromide
Dextromethorphan [USP:INN:BAN]
Dextromethorphan hydrobromide
Dextromethorphan hydrobromide OROS Tablets
Dextromethorphan hydrobromide [BAN:JAN]
Dextromethorphan hydrobromide monohydrate
Dextromethorphane
Dextromethorphane [INN-French]
Dextromethorphanum
Dextromethorphanum [INN-Latin]
Dextrometorfano
Dextrometorfano [INN-Spanish]
Dextrometorphan
Dextromorphan
Dextrométhorphane
Dexyromethorphan
 
Diabe-Tuss DM Syrup
Dimacol
Dimetapp DM
Dormetan
Dormethan
Drixoral Cough
Drixoral Cough & Congestion
Drixoral Cough & Sore Throat
EINECS 204-751-7
EINECS 204-752-2
Endotussin-NN
Endotussin-NN Pediatric
HMS2090C08
HSDB 3056
Hihustan M.
Hold
Hold DM
Koffex DM
L-Methorphan
LS-91837
LS-91838
Levomethorphan
Levomethorphan [BAN:DCF:INN]
Levomethorphan [Ban:Dcf:Inn]
Levomethorphan [INN:BAN:DCF]
Levomethorphane
Levomethorphane [INN-French]
Levomethorphanum
Levomethorphanum [INN-Latin]
Levometorfano
Levometorfano [INN-Spanish]
Lopac-D-2531
Lopac0_000337
MLS000758303
Medicon
Methorate
Methorate Hydrobromide
Methorphan
Metrorat
Mielim Y Mas
MolPort-003-940-943
MolPort-004-285-957
Morphinan, 3-methoxy-17-methyl-, (9-alpha,13-alpha,14-alpha)- (9CI)
NCGC00015333-01
NCGC00015333-02
NCGC00015333-04
NCGC00162126-01
Naldecon-DX
Novahistex DM
Novahistine DM
Ornex Severe Cold Formula
Orthoxicol
PediaCare 1
PediaCare Cough-Cold Formula
Pertussin CS Children's Strength
Pertussin DM Extra Strength
Prestwick0_000359
Prestwick1_000359
Prestwick2_000359
Prestwick3_000359
Prestwick_686
RACEMETHORPHAN
Robitussin CF
Robitussin Cold & Cough
Robitussin Cough Calmers
Robitussin DM
Robitussin Maximum Strength Cough
Robitussin Maximum Strength Cough Suppressant
Robitussin Pediatric
Robitussin Pediatric Cough
Robitussin Pediatric Cough & Cold
Robitussin Pediatric Cough Suppressant
Robitussin Pediatric Night Relief
Romilar
Rondec dm
Ru-Tuss Expectorant
SPBio_002378
St. Joseph Cough Syrup
Sucrets 4 Hour Cough Suppressant
Sudafed Cough Syrup
Triaminic
Triaminic DM Long Lasting for Children
Trind-DM
Trocal
Tusilan
Tussade
Tussar DM
Tussi-Organidin
Tussi-Organidin DM NR
Tussi-Organidin DM-S NR
Tylenol Cold No Drowsiness
Tylenol Cold and Flu Multi-Symptom
Tylenol Cold and Flu No Drowsiness
Tylenol Cough + Decongestant Liquid
Tylenol Cough Liquid
Tylenol Flu No Drowsiness Gelcaps
UNII-7355X3ROTS
Vicks 44 Cough Relief
Viro-Med
d-Methorphan
delta-Methorphan
dextromethorphan
l-Methorphan
9Lithium CarbonatePhase 1, Phase 2206
10RadiopharmaceuticalsPhase 2345
11Fluorodeoxyglucose F18Phase 2340
12Quinidine gluconatePhase 241
13taxanePhase 1313

Interventional clinical trials:

(show all 18)
idNameStatusNCT IDPhase
1DaTSCAN Imaging in Aging and Neurodegenerative DiseaseEnrolling by invitationNCT01453127Phase 4
2Effects of Coenzyme Q10 in PSP and CBDCompletedNCT00532571Phase 2, Phase 3
3A Pilot Trial of Lithium in Subjects With Progressive Supranuclear Palsy or Corticobasal DegenerationCompletedNCT00703677Phase 1, Phase 2
4The Differential Diagnosis of Parkinson's Disease and Parkinsonism by Positron-emission TomographyCompletedNCT01824056Phase 2
5Electrical Polarization of the Brain in Corticobasal SyndromeCompletedNCT00273897Phase 2
6Davunetide (AL-108) in Predicted Tauopathies - Pilot StudyActive, not recruitingNCT01056965Phase 2
7Safety, Tolerability and Efficacy of AVP-786 for the Treatment of DisinhibitionNot yet recruitingNCT02534038Phase 2
8Safety Study of TPI-287 to Treat CBS and PSPRecruitingNCT02133846Phase 1
9Tau Imaging in Subjects With Progressive Supranuclear Palsy, Corticobasal Degeneration and Healthy VolunteersActive, not recruitingNCT02167594Phase 1
10Repetitive Transcranial Magnetic Stimulation (TMS) for Progressive Supranuclear Palsy and Corticobasal DegenerationCompletedNCT01174771
11Study of Tongue PressuresCompletedNCT00013832
124 Repeat Tauopathy Neuroimaging InitiativeRecruitingNCT01804452
13Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)RecruitingNCT02365922
14Study for the Early Diagnosis of Parkinson's DiseaseRecruitingNCT02283073
15Defining Phenotypes of Movement Disorders :Parkinson's Plus Disorders, PD,Essential Tremor, (ET),Cortical Basal Degeneration, (CBD),Multiple Systems Atrophy (MSA), MagnetoencephalographyActive, not recruitingNCT02132052
16Parkinson's Disease, Diagnostic Observations (PADDO)Active, not recruitingNCT01249768
17The Sunnybrook Dementia Study: Mapping Brain Changes in Alzheimer's, Vascular and Other DementiasActive, not recruitingNCT01800214
18Innovative Biomarkers in Alzheimer's Disease and Frontotemporal Dementia (FTD): Preventative and PersonalizedNot yet recruitingNCT01403519

Search NIH Clinical Center for Corticobasal Degeneration

Genetic Tests for Corticobasal Degeneration

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Anatomical Context for Corticobasal Degeneration

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MalaCards organs/tissues related to Corticobasal Degeneration:

33
Cortex, Brain, Eye, Thalamus, Spinal cord

Animal Models for Corticobasal Degeneration or affiliated genes

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MGI Mouse Phenotypes related to Corticobasal Degeneration:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053759.2CRYAB, HSPB2, PITX3, TARDBP
2MP:00053908.4CRYAB, GBA, HSPB2, PITX3, TARDBP, UCHL1
3MP:00053918.4CFL1, CRYAB, HSPB2, MAPT, PITX3
4MP:00107717.7CFL1, CSF3, GBA, MAPT, PITX3, UCHL1
5MP:00053787.3CFL1, CRYAB, GBA, HSPB2, MAPT, PITX3
6MP:00053877.3CRYAB, CSF3, GBA, HSPB2, MAPT, PITX3
7MP:00053867.1CFL1, CRYAB, GBA, HSPB2, MAPT, PITX3
8MP:00036316.9CFL1, CRYAB, GBA, HSPB2, MAPT, PITX3

Publications for Corticobasal Degeneration

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Articles related to Corticobasal Degeneration:

(show top 50)    (show all 387)
idTitleAuthorsYear
1
Therapeutic interventions in parkinsonism: Corticobasal degeneration. (26382843)
2015
2
A disease-specific metabolic brain network associated with corticobasal degeneration. (25208922)
2014
3
Argyrophilic grains are reliable disease-specific features of corticobasal degeneration. (24335531)
2014
4
Analysis of PITX3 gene in patients with multisystem atrophy, progressive supranuclear palsy and corticobasal degeneration. (23694789)
2013
5
A case of an arachnoid cyst masquerading as corticobasal degeneration. (23061395)
2012
6
A case of Creutzfeldt-Jakob disease mimicking corticobasal degeneration: FDG PET, SPECT, and MRI findings. (22691528)
2012
7
Acalculia in autopsy-proven corticobasal degeneration. (21321355)
2011
8
Seizures in corticobasal degeneration: a case report. (19544144)
2009
9
Clinicopathological and genetic correlates of frontotemporal lobar degeneration and corticobasal degeneration. (18357425)
2008
10
Corticobasal degeneration: clinical aspects. (18631773)
2008
11
Dysfunctional facial emotional expression and comprehension in a patient with corticobasal degeneration. (17786775)
2007
12
Co-occurrence of radiological features of progressive supranuclear palsy and corticobasal degeneration. (17272907)
2007
13
Rapid eye movement (REM) sleep without atonia in two patients with corticobasal degeneration (CBD). (17055327)
2007
14
Corticobasal degeneration. (18808957)
2007
15
The clinical overlap between the corticobasal degeneration syndrome and other diseases of the frontotemporal spectrum: three case reports. (17726244)
2007
16
Sporadic SCA8 mutation resembling corticobasal degeneration. (15823478)
2005
17
Constant and severe involvement of Betz cells in corticobasal degeneration is not consistent with pyramidal signs: a clinicopathological study of ten autopsy cases. (15735950)
2005
18
Creutzfeldt-Jakob disease mimicking corticobasal degeneration clinical and MRI data of a case. (15795791)
2005
19
Neurosyphilis masquerading as corticobasal degeneration. (15389980)
2004
20
Rapid onset of pergolide-induced pulmonary fibrosis in a patient with corticobasal degeneration. (15222217)
2004
21
Corticobasal degeneration syndrome with basal ganglia calcification: Fahr's disease as a corticobasal look-alike? (12621646)
2003
22
Limb-kinetic apraxia in corticobasal degeneration: clinical and kinematic features. (12518300)
2003
23
Cholinergic neuronal loss in the basal forebrain and mesopontine tegmentum of progressive supranuclear palsy and corticobasal degeneration. (12536222)
2003
24
Pathologically confirmed corticobasal degeneration presenting with visuospatial dysfunction. (14581681)
2003
25
Voxel-based comparison of regional cerebral glucose metabolism between PSP and corticobasal degeneration. (12084445)
2002
26
Unilateral periodic limb movements during sleep in corticobasal degeneration. (11748759)
2001
27
Intracellular processing of aggregated tau differs between corticobasal degeneration and progressive supranuclear palsy. (11303763)
2001
28
Phenotypes and prognosis: clinicopathologic studies of corticobasal degeneration. (10624482)
2000
29
Aphasia in corticobasal degeneration. (10624476)
2000
30
Immunohistochemistry distinguishes: between Pick's disease and corticobasal degeneration. (11185644)
2000
31
Neuropsychiatric aspects of corticobasal degeneration. (10624478)
2000
32
The corticobasal degeneration syndrome overlaps progressive aphasia and frontotemporal dementia. (11087783)
2000
33
Fragmentation of the Golgi apparatus of the ballooned neurons in patients with corticobasal degeneration and Creutzfeldt-Jakob disease. (10965796)
2000
34
Cerebral blood flow in corticobasal degeneration and progressive supranuclear palsy. (10718204)
2000
35
Contribution of PET studies in diagnosis of corticobasal degeneration. (10894990)
2000
36
Cognitive and magnetic resonance imaging aspects of corticobasal degeneration and progressive supranuclear palsy. (10449111)
1999
37
Neurofibrillary degeneration in progressive supranuclear palsy and corticobasal degeneration: tau pathologies with exclusively "exon 10" isoforms. (10037497)
1999
38
A comparison of tau protein in cerebrospinal fluid between corticobasal degeneration and progressive supranuclear palsy. (10025574)
1999
39
Heterogeneity of glucose metabolism in corticobasal degeneration. (9879684)
1998
40
Neuropsychological and neuroimaging correlates in corticobasal degeneration. (10933454)
1998
41
Increased CSF tau protein in corticobasal degeneration. (9457628)
1998
42
Paired helical filaments in corticobasal degeneration: the fine fibrillary structure with NanoVan. (9409702)
1997
43
Ultrastructural instability of paired helical filaments from corticobasal degeneration as examined by scanning transmission electron microscopy. (8702002)
1996
44
Epitope expression and hyperphosphorylation of tau protein in corticobasal degeneration: differentiation from progressive supranuclear palsy. (7572077)
1995
45
Unique myoclonic pattern in corticobasal degeneration. (7753055)
1995
46
Corticobasal degeneration: a disease with widespread appearance of abnormal tau and neurofibrillary tangles, and its relation to progressive supranuclear palsy. (7985491)
1994
47
Unusual case of corticobasal degeneration with tau/Gallyas-positive neuronal and glial tangles. (7879609)
1994
48
Corticobasal degeneration: a report of three cases. (8046710)
1994
49
Argyrophilic thread-like structure in corticobasal degeneration and supranuclear palsy. (7526285)
1994
50
Corticobasal degeneration: decreased and asymmetrical glucose consumption as studied with PET. (1484530)
1992

Variations for Corticobasal Degeneration

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Expression for genes affiliated with Corticobasal Degeneration

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Search GEO for disease gene expression data for Corticobasal Degeneration.

Pathways for genes affiliated with Corticobasal Degeneration

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GO Terms for genes affiliated with Corticobasal Degeneration

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Cellular components related to Corticobasal Degeneration according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1myelin sheathGO:00432099.7CRYAB, RPS27A, UCHL1
2extracellular exosomeGO:00700627.3CFL1, CRYAB, GBA, PGAM1, PRDX5, RPS27A
3cytoplasmGO:00057376.9CFL1, CRYAB, HSPB2, MAPT, PGAM1, PRDX5

Biological processes related to Corticobasal Degeneration according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1adult walking behaviorGO:000762810.1MAPT, UCHL1
2negative regulation of intracellular transportGO:003238710.0CRYAB, MAPT
3lens development in camera-type eyeGO:00020889.8CRYAB, PITX3
4negative regulation of MAP kinase activityGO:00434079.7GBA, UCHL1
5negative regulation of apoptotic processGO:00430668.4CFL1, CRYAB, PRDX5, RPS27A

Sources for Corticobasal Degeneration

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet