MCID: CRN035
MIFTS: 41

Cranial Nerve Palsy malady

Neuronal diseases category

Summaries for Cranial Nerve Palsy

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32MalaCards
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MalaCards: Cranial Nerve Palsy, also known as cranial nerve paralysis, is related to adenoma and prostatitis. An important gene associated with Cranial Nerve Palsy is NDUFA2 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa), and among its related pathways are Glycolysis and gluconeogenesis (short map) and Pyruvate metabolism. The compounds UBIQUINONE-1 and exisulind have been mentioned in the context of this disorder. Affiliated tissues include pituitary, brain and t cells.

Aliases & Classifications for Cranial Nerve Palsy

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Sources:
8Disease Ontology, 60UMLS, 39NCIt, 34MeSH, 56SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

cranial nerve palsy 8
cranial nerve paralysis 8
cranial nerve palsies 60


External Ids:

Disease Ontology8 DOID:3817
NCIt39 C26941
SNOMED-CT56 73013002
MeSH34 D003389

Related Diseases for Cranial Nerve Palsy

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Sources:
17GeneCards, 18GeneDecks
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Diseases in the Multiple Cranial Nerve Palsy family:

cranial nerve palsy

Diseases related to Cranial Nerve Palsy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 175)
idRelated DiseaseScoreTop Affiliating Genes
1adenoma30.4APC
2prostatitis30.1KLK3
3paraganglioma and gastric stromal sarcoma30.1SDHD, SDHC
4chondroma30.1SDHC, SDHD
5neurofibromatosis30.1SDHC, SDHD
6multiple cranial nerve palsy10.9
7fourth cranial nerve palsy10.7
8carotid artery dissection10.6
9meningitis10.6
10familial congenital fourth cranial nerve palsy10.6
11cerebritis10.5
12wegener's granulomatosis10.5
13pituitary apoplexy10.5
14nasopharyngitis10.5
15cerebral palsy10.5
16intracranial hypotension10.5
17systemic lupus erythematosus10.4
18herpes zoster10.4
19lupus erythematosus10.4
20neuropathy10.4
21melkersson-rosenthal syndrome10.4
22cranial nerve disease10.4
23lemierre's syndrome10.3
24wound botulism10.3
25aseptic meningitis10.3
26arachnoiditis10.3
27intracranial aneurysm10.3
28lyme disease10.3
29hepatitis b10.3
30infectious mononucleosis10.3
31adult-onset still's disease10.3
32bacterial meningitis10.3
33botulism10.3
34hepatitis10.3
35hypopituitarism10.3
36leukemia10.3
37migraine10.3
38multiple myeloma10.3
39myeloma10.3
40otitis externa10.3
41retinitis10.3
42rhabdomyosarcoma10.3
43sarcoidosis10.3
44brown-vialetto-van laere syndrome 110.3
45tolosa-hunt syndrome10.1
46bell's palsy10.1
47sc phocomelia syndrome10.1
48diabetic autonomic neuropathy10.1
49oculomotor nerve paralysis10.1
50autonomic neuropathy10.1

Graphical network of the top 20 diseases related to Cranial Nerve Palsy:



Diseases related to cranial nerve palsy

Clinical Features for Cranial Nerve Palsy

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Drugs & Therapeutics for Cranial Nerve Palsy

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Cranial Nerve Palsy

Drug clinical trials:

Search ClinicalTrials for Cranial Nerve Palsy

Search NIH Clinical Center for Cranial Nerve Palsy

Search CenterWatch for Cranial Nerve Palsy

Genetic Tests for Cranial Nerve Palsy

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Anatomical Context for Cranial Nerve Palsy

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Sources:
32MalaCards
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MalaCards organs/tissues related to Cranial Nerve Palsy:

32
Pituitary, Brain, T cells, Tongue, Cervix, Prostate, Salivary gland, Colon, Cortex, Eye

Animal Models for Cranial Nerve Palsy or affiliated genes

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Publications for Cranial Nerve Palsy

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50PubMed
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Articles related to Cranial Nerve Palsy:

(show top 50)    (show all 232)
idTitleAuthorsYear
1
Fourth Cranial Nerve Palsy and Bilateral Acute Retinal Necrosis following Human Herpesvirus 6 Infection of the Central Nervous System. (24328436)
2013
2
Rhino-oculo Cerebral Mucormycosis with Multiple Cranial Nerve Palsy in Diabetic Patient: Review of Six Cases. (24427603)
2013
3
Isolated III cranial nerve palsy: a surprising presentation of an acute on chronic subdural haematoma. (23784767)
2013
4
Widespread cranial nerve palsies while on cyclophosphamide therapy: a very rare manifestation of Wegener's granulomatosis (granulomatosis with polyangitis). (24142466)
2013
5
Cranial nerve palsy in tuberculous meningitis versus acute bacterial meningitis. (24338201)
2013
6
Review: oculomotor cranial nerve palsies: symptoms, problems and non-surgical preoperative management of the resultant complex incomitant strabismus and monocular and binocular vision disturbances. (22404089)
2012
7
Cerebral venous thrombosis presenting as multiple lower cranial nerve palsies. (23559730)
2012
8
Midbrain neurocysticercosis presenting as isolated pupil sparing third cranial nerve palsy. (21906754)
2012
9
Prognostic value of pretreatment and recovery duration of cranial nerve palsy in nasopharyngeal carcinoma. (22958729)
2012
10
Frontal sinus lymphoma presenting as progressive multiple cranial nerve palsy. (22028175)
2011
11
Isolated sixth cranial nerve palsy as the presenting symptom of a rapidly expanding ACTH positive pituitary adenoma: a case report. (21272327)
2011
12
Cranial nerve VII palsy as the first sign of cephalic tetanus after an earthquake. (21482936)
2011
13
Bell's palsy with concomitant idiopathic cranial nerve polyneuropathy in seven dogs. (21726231)
2011
14
Acute bilateral retinal hemorrhages and unilateral sixth cranial nerve palsy after inadvertent epidural anaesthetic injection and subsequent dural puncture. (20436528)
2010
15
Fourth cranial nerve palsy in a collegiate lacrosse player: a case report. (20617917)
2010
16
Cranial nerve palsy in multiple myeloma and solitary plasmacytoma. (21114773)
2010
17
The Case: Cranial nerve palsy and acute renal failure after a 'special drink'. (20186164)
2010
18
Delayed cranial nerve palsy after coiling of carotid cavernous sinus aneurysms: case report. (20495397)
2010
19
Development of cranial nerve palsy shortly after endosaccular embolization for asymptomatic cerebral aneurysm: report of two cases and literature review. (19262981)
2009
20
Sarcoidosis presenting with complete atrio-ventricular block and cranial nerve palsy. (19736585)
2009
21
Adult-onset Still's disease complicated by multiple cranial nerve palsy and hypothyroidism. (18419687)
2008
22
Unruptured large and giant carotid artery aneurysms presenting with cranial nerve palsy: comparison of clinical recovery after selective aneurysm coiling and therapeutic carotid artery occlusion. (18296545)
2008
23
Pituitary apoplexy presenting as acute painful isolated unilateral third cranial nerve palsy. (18588383)
2008
24
Clinical features and natural history of acquired third, fourth, and sixth cranial nerve palsy. (17293794)
2008
25
Unilateral lower cranial nerve palsies as the sole manifestation of internal carotid artery dissection: Case report. (18642353)
2008
26
Multiple cranial nerve palsies in testicular lymphoma: report of a case. (17622916)
2007
27
Simultaneous ischemic optic neuropathy and third cranial nerve palsy in giant cell arteritis. (18090573)
2007
28
Traumatic cranial nerve palsy. (16525155)
2006
29
Sixth cranial nerve palsy caused by compression from a dolichoectatic vertebral artery. (15937439)
2005
30
Sixth cranial nerve palsy. (16029834)
2005
31
Images in clinical medicine. Traumatic cranial nerve palsy. (16267326)
2005
32
Isolated 12th cranial nerve palsy as a complication of multiple myeloma. (14675400)
2004
33
Unilateral sixth cranial nerve palsy caused by skull base mass lesions: case series. (11771050)
2001
34
Combined fourth and sixth cranial nerve palsy after lumbar puncture: a rare complication. A case report. (11702640)
2001
35
Unilateral congenital third cranial nerve palsy with central nervous system anomalies: report of two cases. (11416899)
2000
36
Jugular bulb diverticulum associated with lower cranial nerve palsy and multiple aneurysms. (10940423)
2000
37
Fourth cranial nerve palsy in pediatric patients with pseudotumor cerebri. (10030583)
1999
38
Cranial nerve palsy as a complication of operative traction. (10101825)
1999
39
Unusual cranial nerve palsy caused by cavernous sinus aneurysms. Clinical and anatomical considerations reviewed. (10447280)
1999
40
Pediatric ethmoid chondroma incidentally found during evaluation of a third cranial nerve palsy. (10605925)
1999
41
Transient oculomotor cranial nerves palsy in spontaneous intracranial hypotension. (10192060)
1998
42
Abdominal pain associated with cranial nerve palsy and peripheral neuropathy. (9196709)
1997
43
Cranial nerve palsies and cerebral infarction in a young infant with meningococcal meningitis. (7784819)
1995
44
Cranial nerve palsy in childhood acute lymphoblastic leukemia and non-Hodgkin's lymphoma. (2013032)
1991
45
Bony exostosis of the atlas with resultant cranial nerve palsy. (1749482)
1991
46
Cranial nerve palsy following retrobulbar anaesthesia. (3342224)
1988
47
Lower cranial nerve palsy produced by internal carotid artery dilatation. Report of two cases. (3679788)
1987
48
Fourth cranial nerve palsy following spinal anesthesia. A case report. (2952674)
1987
49
Radiation-induced cranial nerve palsy. (195702)
1977
50
Inferior rectus palsies as a manifestation of atypical IIIrd cranial nerve disease. (1200458)
1975

Genetic Variations for Cranial Nerve Palsy

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Expression for genes affiliated with Cranial Nerve Palsy

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cranial Nerve Palsy

Search GEO for disease gene expression data for Cranial Nerve Palsy.

Pathways for genes affiliated with Cranial Nerve Palsy

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Sources:
12EMD Millipore, 37NCBI BioSystems Database, 53Reactome, 29KEGG
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Pathways related to Cranial Nerve Palsy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.8SDHC, SDHD
2
Hide members
9.8SDHC, SDHD
3
Hide members
9.8SDHC, SDHD
48.9PGLS, SDHD, SDHC
5
Hide members
8.6SDHC, SDHD, SLC52A3, PGLS

Compounds for genes affiliated with Cranial Nerve Palsy

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Sources:
11DrugBank, 44Novoseek, 24HMDB, 28IUPHAR, 49PharmGKB
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Compounds related to Cranial Nerve Palsy according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1UBIQUINONE-11110.0SDHC, SDHD
2exisulind4410.0APC, KLK3
32-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol1110.0SDHC, SDHD
4thymine44 2410.9XPC, APC
5fumarate44 1110.9SDHC, SDHD
6lycopene44 2410.9KLK3, CRP
7iron-sulfur449.8SDHC, SDHD
8succinic acid28 11 2411.8SDHC, SDHD
9ubiquinone449.5SDHC, SDHD
10aspirin44 49 28 2412.4KLK3, APC, CRP
11iron44 2410.4NDUFA2, CRP, SDHD, SDHC

GO Terms for genes affiliated with Cranial Nerve Palsy

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16Gene Ontology
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Cellular components related to Cranial Nerve Palsy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial respiratory chain complex IIGO:0057499.8SDHC, SDHD

Biological processes related to Cranial Nerve Palsy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1tricarboxylic acid cycleGO:0060999.8SDHC, SDHD
2respiratory electron transport chainGO:0229049.4SDHC, SDHD, NDUFA2
3cellular metabolic processGO:0442379.2SDHC, SDHD, NDUFA2

Products for genes affiliated with Cranial Nerve Palsy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cranial Nerve Palsy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet