Aliases & Classifications for Cranial Nerve Palsy

Aliases & Descriptions for Cranial Nerve Palsy:

Name: Cranial Nerve Palsy 12 14
Cranial Nerve Paralysis 12 29
Cranial Nerve Diseases 42 69
Cranial Nerve Palsies 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3817
MeSH 42 D003389
NCIt 47 C26941
SNOMED-CT 64 73013002
ICD10 33 G53 G52.8
UMLS 69 C0151311

Summaries for Cranial Nerve Palsy

MalaCards based summary : Cranial Nerve Palsy, also known as cranial nerve paralysis, is related to fourth cranial nerve palsy and multiple cranial nerve palsy, and has symptoms including ophthalmoplegia, circumoral paresthesia and neurologic symptoms. An important gene associated with Cranial Nerve Palsy is APC (APC, WNT Signaling Pathway Regulator), and among its related pathways/superpathways is G12-G13 in Cellular Signaling. The drugs Dopamine and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include pituitary, t cells and brain.

Related Diseases for Cranial Nerve Palsy

Diseases in the Cranial Nerve Palsy family:

Multiple Cranial Nerve Palsy

Diseases related to Cranial Nerve Palsy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 138)
id Related Disease Score Top Affiliating Genes
1 fourth cranial nerve palsy 12.4
2 multiple cranial nerve palsy 12.3
3 cranial nerve disease 12.3
4 fourth cranial nerve palsy, familial congenital 12.1
5 third cranial nerve disease 12.0
6 brown-vialetto-van laere syndrome 1 11.1
7 oculomotor nerve paralysis 11.1
8 bell's palsy 11.1
9 abducens nerve disease 11.1
10 congenital oculomotor nerve palsy 11.1
11 congenital abducens nerve palsy 11.1
12 congenital trochlear nerve palsy 11.1
13 cowden syndrome 1 10.9
14 behcet syndrome 10.9
15 tolosa-hunt syndrome 10.9
16 glomus vagale tumor 10.9
17 optic nerve disease 10.7
18 aneurysm 10.3
19 iliac vein thrombophlebitis 10.2 APC CHN1
20 meningitis 10.1
21 carotid artery dissection 10.1
22 lymphoma 10.1
23 pituitary apoplexy 10.1
24 sertoli cell tumor 10.1 NT5C3A RHNO1
25 nasopharyngitis 10.1
26 cerebritis 10.1
27 bestiality 10.1 CHN1 RHNO1
28 testicular gonadoblastoma 10.0 NT5C3A RHNO1
29 vulvar disease 10.0 RHNO1 SCYL1
30 seminal vesicle tumor 10.0 NT5C3A SLC25A16
31 chronic lacrimal gland enlargement 10.0 CHN1 NT5C3A
32 nasopharyngeal carcinoma 10.0
33 intracranial hypotension 10.0
34 neuropathy 10.0
35 systemic lupus erythematosus 10.0
36 arachnoiditis 10.0
37 herpes zoster 10.0
38 lupus erythematosus 10.0
39 arachnoid cysts 10.0
40 gastric ulcer 10.0 RHNO1 SLC25A16
41 strabismus 9.9
42 herpes zoster ophthalmicus 9.9
43 spontaneous intracranial hypotension 9.9
44 acute laryngitis 9.9 RHNO1 SCYL1
45 melkersson-rosenthal syndrome 9.8
46 multiple myeloma 9.8
47 hepatitis 9.8
48 leukemia 9.8
49 sinusitis 9.8
50 thrombosis 9.8

Comorbidity relations with Cranial Nerve Palsy via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Cranial Nerve Palsy:



Diseases related to Cranial Nerve Palsy

Symptoms & Phenotypes for Cranial Nerve Palsy

UMLS symptoms related to Cranial Nerve Palsy:


ophthalmoplegia, circumoral paresthesia, neurologic symptoms

Drugs & Therapeutics for Cranial Nerve Palsy

Drugs for Cranial Nerve Palsy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 587)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4,Phase 3,Phase 1,Phase 2 51-61-6, 62-31-7 681
2
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-02-2 5743
3
Mitoxantrone Approved, Investigational Phase 4,Phase 2 65271-80-9 4212
4
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 3 51-43-4 5816
5
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
6
Morphine Approved, Investigational Phase 4 57-27-2 5288826
7
Acetaminophen Approved Phase 4 103-90-2 1983
8
4-Aminopyridine Approved Phase 4,Phase 2,Phase 3 504-24-5 1727
9
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
10
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
11
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
12
Bupivacaine Approved, Investigational Phase 4,Phase 2,Phase 3 2180-92-9, 38396-39-3 2474
13
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
14
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2 2078-54-8 4943
15
Menthol Approved Phase 4,Phase 3,Early Phase 1 2216-51-5 16666
16
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
17
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
18
Bevacizumab Approved, Investigational Phase 4,Phase 2,Phase 1,Early Phase 1 216974-75-3
19
Desflurane Approved Phase 4 57041-67-5 42113
20
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 53-03-2 5865
21
Gabapentin Approved, Investigational Phase 4,Phase 2 60142-96-3 3446
22
Cocaine Approved, Illicit Phase 4,Phase 2 50-36-2 5760 446220
23
Levodopa Approved Phase 4 59-92-7 6047
24
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
25
Warfarin Approved Phase 4 81-81-2 6691 54678486
26
Acetylcholine Approved Phase 4,Phase 3,Phase 1,Phase 2 51-84-3 187
27
Memantine Approved, Investigational Phase 4,Phase 2 19982-08-2 4054
28
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
29
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
30
Sulfadiazine Approved, Vet_approved Phase 4 68-35-9 5215
31
Brinzolamide Approved Phase 4 138890-62-7 68844
32
Sulfamethoxazole Approved Phase 4 723-46-6 5329
33 Idebenone Approved, Investigational Phase 4,Phase 3,Phase 2 58186-27-9
34
Carbidopa Approved Phase 4 28860-95-9 34359 38101
35
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
36
Pyrimethamine Approved, Vet_approved Phase 4 58-14-0 4993
37
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
38
Benzocaine Approved Phase 4,Phase 2,Phase 3,Phase 1 1994-09-7, 94-09-7 2337
39
Natalizumab Approved, Investigational Phase 4,Phase 2,Phase 3 189261-10-7
40
Fluorometholone Approved Phase 4 426-13-1 9878
41
Interferon beta-1a Approved, Investigational Phase 4,Phase 3 145258-61-3 6438354
42
Rimexolone Approved Phase 4 49697-38-3 39507
43
Cosyntropin Approved Phase 4 16960-16-0 16129617
44
Povidone-iodine Approved Phase 4 25655-41-8
45
Methotrexate Approved Phase 4,Phase 2,Phase 3 1959-05-2, 59-05-2 126941
46
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
47
Minocycline Approved, Investigational Phase 4,Phase 2 10118-90-8 5281021
48
Isotretinoin Approved Phase 4 4759-48-2 5538 5282379
49
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
50
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635

Interventional clinical trials:

(show top 50) (show all 968)
id Name Status NCT ID Phase
1 Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders Unknown status NCT02021825 Phase 4
2 A Phase IV Trial of Neuroprotection With ACTH in Acute Optic Neuritis Unknown status NCT01838174 Phase 4
3 Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization Unknown status NCT01029938 Phase 4
4 Comparing Carotid Stenting With Endarterectomy in Severe Asymptomatic Carotid Stenosis Unknown status NCT00772278 Phase 4
5 Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit Unknown status NCT00862160 Phase 4
6 Serratus Anterior Plane Block Versus Paravertebral Block for Postmastectomy Analgesia Unknown status NCT02103946 Phase 4
7 Use of Bevacizumab in Trabeculectomy Surgery Completed NCT01166594 Phase 4
8 Ocular-hypertensive Response to Topical Steroids in Children After Bilateral Strabismus Surgery Completed NCT02816905 Phase 4
9 The Effect of Anaesthesia Depth on Oculo-cardiac Reflex Completed NCT02379546 Phase 4
10 Comparison of Two Treatments for Strabismus Correction: Botulinum Toxin A Associated to Surgery and Surgery Alone Completed NCT01460355 Phase 4
11 Neural Conduction Along the Visual Pathways After Oral Treatment With Citicoline in Patients With Optic Nerve Diseases Completed NCT00404729 Phase 4
12 A New Medicine to Treat Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) Completed NCT01975324 Phase 4
13 Effect of Levodopa-Carbidopa on Visual Function in Patients With Recent-Onset Nonarteritic Anterior Ischemic Optic Neuropathy Completed NCT00432393 Phase 4
14 Povidone-iodine Antisepsis for Strabismus Surgery Completed NCT00461656 Phase 4
15 Topical Brinzolamide Ophthalmic Suspension Versus Placebo in the Treatment of Infantile Nystagmus Syndrome Completed NCT01312402 Phase 4
16 A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic’s Disease) Completed NCT00304291 Phase 4
17 Pegaptanib for Retinal Edema Secondary to Diabetic Vascular Disease(Preserve) Study Completed NCT01486238 Phase 4
18 Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis Completed NCT00179478 Phase 4
19 Surface Acoustic Wave Ultrasound in Trigeminal Neuralgia Pain Completed NCT01447108 Phase 4
20 Efficacy of Single-Shot Dexmedetomidine Versus Placebo in Preventing Pediatric Emergence Delirium in Strabismus Surgery Completed NCT01901588 Phase 4
21 Comparison of Three Botulinum Neuromodulators for Management of Facial Synkinesis Completed NCT03048383 Phase 4
22 Treatment of Pendular Nystagmus in OPT Completed NCT02466191 Phase 4
23 Scandinavian Bell's Palsy Study Completed NCT00510263 Phase 4
24 Effects of Dexmedetomidine Premedication on Emergence Agitation After Strabismus Surgery in Children Completed NCT01895023 Phase 4
25 Treatment of Cerebral Toxoplasmosis in HIV/AIDS Completed NCT00367081 Phase 4
26 Diclofenac Administered Before Skull Operations Reduces the Severity of Headache After the Intervention Completed NCT01907984 Phase 4
27 Cosyntropin Versus Epidural Blood Patch (EBP) for Treatment of Treatment of Post Dural Puncture Headache Completed NCT02394457 Phase 4
28 Antiacne Medications Pseudotumor Cerebri Recruiting NCT02149615 Phase 4
29 Study to Assess the Efficacy and Safety of Raxone in LHON Patients Recruiting NCT02774005 Phase 4
30 Citicoline Effect on Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) Recruiting NCT03046693 Phase 4
31 Acute Unilateral Vestibulopathy and Corticosteroid Treatment Recruiting NCT02912182 Phase 4
32 PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) Recruiting NCT00867815 Phase 4
33 Gentamicin Treatment Prior to Schwannoma Surgery - No Residual Function Recruiting NCT02415257 Phase 4
34 Gentamicin Treatment Prior to Schwannoma Surgery - Residual Function Recruiting NCT02379754 Phase 4
35 The Paediatric EVICEL® Neuro Study Recruiting NCT02309645 Phase 4
36 Cavernous Sinus Dissection and Bleeding in Meningiomas Recruiting NCT02863484 Phase 4
37 Impact of Anticoagulation Therapy on the Cognitive Decline and Dementia in Patients With Non-Valvular Atrial Fibrillation Recruiting NCT03061006 Phase 4
38 Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions Recruiting NCT03014687 Phase 4
39 A Comparison of Stryker Hybrid Arch Bars Recruiting NCT02283528 Phase 4
40 Safety and Effectiveness of Switching Relapsing MS Patients Treated With Natalizumab at Risk for PML to Teriflunomide Active, not recruiting NCT01970410 Phase 4
41 Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients Enrolling by invitation NCT02809079 Phase 4
42 Postoperative Analgesia in Patients With Microvascular Decompression Not yet recruiting NCT03152955 Phase 4
43 A Prospective Controlled Treatment Trial for Post-Traumatic Headaches Not yet recruiting NCT03007420 Phase 4
44 Comparison of Total Intravenous Anesthesia vs. Inhalational Anesthesia in Acute Subdural Hematoma Patients Not yet recruiting NCT03146104 Phase 4
45 Cacicol20® in Corneal Wound Healing and Nerve Regeneration After Phototherapeutic Keratectomy Terminated NCT02373397 Phase 4
46 Evaluation of Safety and Efficacy of Nasea(R)/Ramosetron Inj. in Patients Undergoing Facial Bone Fracture Operations Terminated NCT01637545 Phase 4
47 Duration of Postoperative Antibiotic Prophylaxis in Facial Fractures Terminated NCT01583062 Phase 4
48 Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event. Withdrawn NCT00037115 Phase 4
49 A Trial of Bifocals in Myopic Children With Esophoria Unknown status NCT00000128 Phase 3
50 Retrobulbar Triamcinolone Acetonide Injection in the Treatment of NA-AION Unknown status NCT02329288 Phase 3

Search NIH Clinical Center for Cranial Nerve Palsy

Cochrane evidence based reviews: cranial nerve diseases

Genetic Tests for Cranial Nerve Palsy

Genetic tests related to Cranial Nerve Palsy:

id Genetic test Affiliating Genes
1 Cranial Nerve Paralysis 29

Anatomical Context for Cranial Nerve Palsy

MalaCards organs/tissues related to Cranial Nerve Palsy:

39
Pituitary, T Cells, Brain, Neutrophil, Breast, Tongue, Cervix

Publications for Cranial Nerve Palsy

Articles related to Cranial Nerve Palsy:

(show top 50) (show all 266)
id Title Authors Year
1
Relapsing polychondritis as an unusual cause of multiple cranial nerve palsies-A Case report. ( 28093782 )
2017
2
Imaging of Oculomotor (Third) Cranial Nerve Palsy. ( 27886888 )
2017
3
Isolated neurosarcoidosis presenting with multiple cranial nerve palsies. ( 27168947 )
2016
4
Radiographic occult cerebellar germinoma presenting with progressive ataxia and cranial nerve palsy. ( 26759273 )
2016
5
Isolated fourth cranial nerve palsy due to pituitary macroadenoma. ( 28050074 )
2016
6
Cerebrospinal fluid dissemination of anaplastic intraventricular meningioma: report of a case presenting with progressive brainstem dysfunction and multiple cranial nerve palsies. ( 27245327 )
2016
7
A rare case of third cranial nerve palsy. ( 27728318 )
2016
8
A case of possible paraneoplastic neurological syndrome presenting as multiple cranial nerve palsies associated with gallbladder cancer. ( 27498818 )
2016
9
Cranial nerve palsy secondary to cerebrospinal fluid diversion. ( 26882270 )
2016
10
A Rare Case of Basioccipital Encephalomeningocele with Tethered Dermoid Presenting as Cranial Nerve Palsy: A Case Report. ( 27318872 )
2016
11
Third, Fourth, and Sixth Cranial Nerve Palsies in Pituitary Apoplexy. ( 27436207 )
2016
12
[Malignant lymphoma presented as recurrent multiple cranial nerve palsy after spontaneous regression of oculomotor nerve palsy: A case report]. ( 26616489 )
2016
13
A frontal external ventricular drain causing a third cranial nerve palsy. ( 27241884 )
2016
14
Third Cranial Nerve Palsy in the Setting of Chikungunya Virus Infection. ( 27246445 )
2016
15
A case of myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-associated hypertrophic pachymeningitis presenting with multiple cranial nerve palsies and diabetes insipidus. ( 27098904 )
2016
16
Tapia's syndrome in the intensive care unit: a rare cause of combined cranial nerve palsy following intubation. ( 26088745 )
2015
17
Residual Strabismus in Children Following Improvement of Cranial Nerve Palsies Affecting Ocular Ductions. ( 26564932 )
2015
18
Sixth cranial nerve palsy caused by gastric adenocarcinoma metastasis to the clivus. ( 25810862 )
2015
19
Radiation-induced lower cranial nerve palsy in patients with head and neck carcinoma. ( 26171186 )
2015
20
Sixth cranial nerve palsy due to acitretin. ( 25997624 )
2015
21
Occipital condyle fracture and lower cranial nerve palsy after blunt head trauma - a literature review and case report. ( 25897322 )
2015
22
Sixth cranial nerve palsy due to arachnoid cyst. ( 25347081 )
2014
23
Sixth cranial nerve palsy due to arachnoid cyst. ( 25608227 )
2014
24
Isolated III cranial nerve palsy: a Hodgkin's lymphoma? ( 24759607 )
2014
25
Pseudo third cranial nerve palsy secondary to orbital ectopic lacrimal gland cyst: management with functional endoscopic sinus surgery. ( 24526481 )
2014
26
Third cranial nerve palsy and Purtscher retinopathy in a child with multiple injuries. ( 25443190 )
2014
27
Metastatic breast cancer presenting as sequential cranial nerve palsy: a case report. ( 25511612 )
2014
28
Traumatic multiple lower cranial nerve palsy: a case report and review of the literature. ( 26022597 )
2014
29
Clinical Features and Outcomes of Strabismus Treatment in Third Cranial Nerve Palsy during a 10-Year Period. ( 25667737 )
2014
30
Incidence, Impact, and Predictors of Cranial Nerve Palsy and Haematoma Following Carotid Endarterectomy in the International Carotid Stenting Study. ( 25344019 )
2014
31
Cyclotropia to differentiate longstanding and acute fourth cranial nerve palsy. ( 25313119 )
2014
32
Management of congenital fourth cranial nerve palsy. ( 24661367 )
2014
33
Transient sixth cranial nerve palsy following orgasm abrogated by treatment with sympathomimetic amines. ( 25134302 )
2014
34
Persistent hiccups and vomiting with multiple cranial nerve palsy in a case of zoster sine herpete. ( 25318806 )
2014
35
Traumatic internal carotid artery pseudoaneurysm. A rare cause of cranial nerve palsy. ( 25109537 )
2014
36
Sixth cranial nerve palsy in isolated sphenoid sinusitis: a case report. ( 24647749 )
2014
37
Isolated third cranial nerve palsy from non-aneurysmal internal carotid artery compression. ( 24652655 )
2014
38
Blepharoptosis Associated With Third Cranial Nerve Palsy. ( 25376747 )
2014
39
Isolated Sixth Cranial Nerve Palsy--An Uncommon Presenting Feature of Multiple Sclerosis. ( 26259320 )
2014
40
Isolated cranial nerve palsies may point to primary histiocytic sarcoma. ( 25123571 )
2014
41
Unusual aetiology of isolated lower motor neuron facial palsy: systemic lupus erythematosus presenting with cranial nerve palsy and nephritis. ( 23978499 )
2013
42
Widespread cranial nerve palsies while on cyclophosphamide therapy: a very rare manifestation of Wegener's granulomatosis (granulomatosis with polyangitis). ( 24142466 )
2013
43
Isolated III cranial nerve palsy: a surprising presentation of an acute on chronic subdural haematoma. ( 23784767 )
2013
44
Cranial nerve palsies: sarcoidosis to systemic lupus erythematosus. ( 23401835 )
2013
45
Glufosinate herbicide intoxication causing unconsciousness, convulsion, and 6th cranial nerve palsy. ( 24265537 )
2013
46
Predictive factors and radiological features of radiation-induced cranial nerve palsy in patients with nasopharyngeal carcinoma following radical radiotherapy. ( 22892236 )
2013
47
Cranial nerve palsy as a factor to differentiate tuberculous meningitis from acute bacterial meningitis. ( 23585318 )
2013
48
Rhino-oculo Cerebral Mucormycosis with Multiple Cranial Nerve Palsy in Diabetic Patient: Review of Six Cases. ( 24427603 )
2013
49
Multiple cranial nerve palsy revealing hypertrophic pachymeningitis with positive myeloperoxidase-antineutrophil cytoplasmic antibody. ( 24399188 )
2013
50
Cranial Nerve Palsy Should Not Be Included within a Primary Composite Endpoint in Carotid Surgery Trials. ( 24183248 )
2013

Variations for Cranial Nerve Palsy

Expression for Cranial Nerve Palsy

Search GEO for disease gene expression data for Cranial Nerve Palsy.

Pathways for Cranial Nerve Palsy

Pathways related to Cranial Nerve Palsy according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.71 APC CHN1

GO Terms for Cranial Nerve Palsy

Biological processes related to Cranial Nerve Palsy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of signal transduction GO:0009967 8.62 CHN1 LAT

Molecular functions related to Cranial Nerve Palsy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 SH3/SH2 adaptor activity GO:0005070 8.62 CHN1 LAT

Sources for Cranial Nerve Palsy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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