MCID: CRN037
MIFTS: 61

Craniosynostosis malady

Categories: Genetic diseases, Rare diseases, Bone diseases, Fetal diseases

Aliases & Classifications for Craniosynostosis

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Aliases & Descriptions for Craniosynostosis:

Name: Craniosynostosis 32 10 45 46 47 12 24 65
Premature Closure of Cranial Sutures 10
Craniosynostoses 36
 
Craniostenosis 45
Cso 45

Classifications:



External Ids:

Disease Ontology10 DOID:2340
ICD1027 Q75.0
MeSH36 D003398
NCIt42 C84655
UMLS65 C0010278

Summaries for Craniosynostosis

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NINDS:46 Craniosynostosis is a birth defect of the skull characterized by the premature closure of one or more of the fibrous joints between the bones of the skull (called the cranial sutures) before brain growth is complete. Closure of a single suture is most common. Normally the skull expands uniformly to accommodate the growth of the brain; premature closure of a single suture restricts the growth in that part of the skull and promotes growth in other parts of the skull where sutures remain open. This results in a misshapen skull but does not prevent the brain from expanding to a normal volume. However, when many sutures close prematurely, the skull cannot expand to accommodate the growing brain, which leads to increased pressure within the skull and impaired development of the brain. Craniosynostosis can be gene-linked or caused by metabolic diseases (such as rickets )or an overactive thyroid. Some cases are associated with other disorders such as microcephaly (abnormally small head) and hydrocephalus (excessive accumulation of cerebrospinal fluid in the brain). The first sign of craniosynostosis is an abnormally shaped skull. Other features can include signs of increased intracranial pressure, developmental delays, or impaired cognitive development, which are caused by constriction of the growing brain. Seizures and blindness may also occur.

MalaCards based summary: Craniosynostosis, also known as premature closure of cranial sutures, is related to craniosynostosis 5 and craniosynostosis, type 1. An important gene associated with Craniosynostosis is MSX2 (Msh Homeobox 2), and among its related pathways are Signal transduction by L1 and Alzheimers Disease Pathway. Affiliated tissues include skull, bone and brain, and related mouse phenotypes are renal/urinary system and endocrine/exocrine gland.

Disease Ontology:10 A synostosis that results in premature fusion located in skull.

NIH Rare Diseases:45 Craniosynostosis is a birth defect of the brain characterized by the premature closure of one or more of the joints between the bones of the skull (called the cranial sutures) before brain growth is complete. the first sign is an abnormally shaped skull; other features can include signs of increased intracranial pressure, developmental delays, intellectual disability, seizures, and blindness, caused by constriction of the growing brain. closure of a single suture is most common and does not prevent the brain from expanding to a normal volume. when many sutures close prematurely, the skull cannot expand to accommodate the growing brain, leading to increased pressure and impaired development of the brain. craniosynostosis can be caused by genetic mutations, certain metabolic diseases (such as rickets or an overactive thyroid) or can be associated with other disorders such as microcephaly and hydrocephalus. treatment generally consists of surgery to improve the symmetry and appearance of the head and to relieve pressure on the brain and the cranial nerves. last updated: 3/31/2011

Wikipedia:68 Craniosynostosis (from cranio, cranium; + syn, together; + ostosis relating to bone) is a condition in... more...

Related Diseases for Craniosynostosis

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Diseases in the Craniosynostosis family:

Craniosynostosis 6 Craniosynostosis, Type 2
Craniosynostosis, Type 1 Craniosynostosis 5
Craniosynostosis 3 Craniosynostosis 4
Craniosynostosis Autosomal Dominant Craniosynostosis, Nonsyndromic
Erf-Related Craniosynostosis Fgfr1-Related Craniosynostosis
Fgfr2-Related Craniosynostosis Fgfr3-Related Craniosynostosis
Msx2-Related Craniosynostosis Tcf12-Related Craniosynostosis
Twist1-Related Craniosynostosis Zic1-Related Craniosynostosis

Diseases related to Craniosynostosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 613)
idRelated DiseaseScoreTop Affiliating Genes
1craniosynostosis 534.0ALX4, MSX2
2craniosynostosis, type 132.9FGFR1, FGFR2, FGFR3, MSX2, RECQL4, TCF12
3beare-stevenson cutis gyrata syndrome32.4ERF, FGFR1, FGFR2, FGFR3, MSX2
4jackson-weiss syndrome32.1FGF8, FGFR1, FGFR2, FGFR3, TWIST1
5apert syndrome31.1FGFR1, FGFR2, FGFR3
6crouzon syndrome with acanthosis nigricans30.9FGFR1, FGFR2, FGFR3
7antley-bixler syndrome without genital anomalies or disordered steroidogenesis30.8FGFR1, FGFR2, FGFR3
8vulvovaginal candidiasis29.5FGFR1, FGFR2, NOG
9critical limb ischemia25.0ALX4, EFNB1, ERF, FGF8, FGFR1, FGFR2
10craniosynostosis, type 212.4
11craniosynostosis and dental anomalies12.4
12craniosynostosis 312.3
13craniosynostosis 412.3
14craniosynostosis 612.3
15craniostenosis cataract12.3
16craniostenosis with congenital heart disease mental retardation12.3
17herrmann opitz craniosynostosis12.3
18msx2-related craniosynostosis12.3
19twist1-related craniosynostosis12.2
20craniosynostosis with radiohumeral fusions and other skeletal and craniofacial anomalies12.2
21craniosynostosis, philadelphia type12.2
22erf-related craniosynostosis12.2
23fgfr2-related craniosynostosis12.2
24tcf12-related craniosynostosis12.2
25craniosynostosis, adelaide type12.1
26fgfr-related craniosynostosis syndromes12.1
27craniosynostosis mental retardation clefting syndrome12.1
28dandy-walker malformation with sagittal craniosynostosis and hydrocephalus12.1
29craniosynostosis, nonsyndromic12.1
30fgfr1-related craniosynostosis12.1
31zic1-related craniosynostosis12.1
32congenital craniosynostosis maternal hyperthyroiditis12.1
33craniosynostosis alopecia brain defect12.1
34craniosynostosis arthrogryposis cleft palate12.1
35craniosynostosis autosomal dominant12.1
36craniosynostosis cleft lip palate arthrogryposis12.1
37craniosynostosis contractures cleft12.1
38craniosynostosis exostoses nevus epibulbar dermoid12.1
39craniosynostosis fontaine type12.1
40craniosynostosis maroteaux fonfria type12.1
41craniosynostosis mental retardation heart defects12.1
42craniosynostosis-mental retardation syndrome of lin and gettig12.1
43cutis gyratum acanthosis nigricans craniosynostosis12.1
44hydrocephalus craniosynostosis bifid nose12.1
45mental retardation anophthalmia craniosynostosis12.1
46short ribs craniosynostosis polysyndactyly12.1
47symphalangism brachydactyly craniosynostosis12.1
48fgfr3-related craniosynostosis12.1
49craniosynostosis-dandy-walker malformation-hydrocephalus syndrome12.1
50osteosclerosis-developmental delay-craniosynostosis syndrome12.1

Graphical network of the top 20 diseases related to Craniosynostosis:



Diseases related to craniosynostosis

Symptoms for Craniosynostosis

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Drugs & Therapeutics for Craniosynostosis

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Drugs for Craniosynostosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 37)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Tranexamic AcidapprovedPhase 4, Phase 32261197-18-85526
Synonyms:
08455_FLUKA
1197-17-7
1197-18-8
1ceb
3-14-00-00868 (Beilstein Handbook Reference)
4-(Aminomethyl)-Cyclohexanecarboxylic Acid
4-(Aminomethyl)cyclohexanecarboxylic acid
4-(aminomethyl)cyclohexane-1-carboxylic acid
857653_ALDRICH
A0236
AB00052260
AB1003647
AC-4687
AC1L1KJH
AC1Q50F3
AC1Q546D
AC1Q5U04
ALBB-006013
AMCA
AMCHA
AMH
AR-1F6595
Acide tranexamique
Acide tranexamique [INN-French]
Acido tranexamico
Acido tranexamico [INN-Spanish]
Acidum tranexamicum
Acidum tranexamicum [INN-Latin]
Amikapron
Amstat
Anvitoff
BAY 3517
BPBio1_000069
BRN 2207452
BSPBio_000061
BSPBio_002837
CAS-1197-18-8
CHEBI:48669
CHEMBL292500
CHEMBL877
CID5526
CL 65336
CL-65336
Carxamin
Cyclocapron
Cyklokapron
Cyklokapron (TN)
D01136
DB00302
DV 79
DV-79
DV79
DivK1c_000655
EINECS 214-818-2
Emorhalt
Exacyl
Frenolyse
HMS1568D03
HMS1921F08
HMS2092P03
HMS502A17
Hexapromin
Hexatron
I04-0993
IDI1_000655
KABI 2161
KBio1_000655
KBio2_001871
KBio2_004439
KBio2_007007
KBio3_002337
KBioGR_000511
KBioSS_001871
 
LS-56611
LS-56612
LT00159441
Lysteda
Mastop
MolPort-001-792-390
MolPort-002-512-008
NCGC00016569-01
NCGC00016569-02
NCGC00016569-03
NCGC00094944-01
NCGC00094944-02
NINDS_000655
NSC 291305
NSC291305
Oprea1_786414
Prestwick0_000171
Prestwick1_000171
Prestwick2_000171
Prestwick3_000171
Prestwick_476
RP 18,429
Rikavarin
Rikavarin (TN)
Rikavarin-S
SPBio_000689
SPBio_001982
SPECTRUM1502026
STK503668
STOCK1N-16183
Spectrum2_000655
Spectrum3_001189
Spectrum4_000046
Spectrum5_001258
Spectrum_001391
Spiramin
Tamcha
Tranex
Tranexamate
Tranexamic Acid
Tranexamic acid (JP15/USAN/INN)
Tranexamic acid [USAN:INN:BAN:JAN]
Tranexamic acid cis-form
Tranexamsaeure
Tranexan
Tranexmic acid
Tranhexamic acid
Trans AMCHA
Trans-1-(Aminomethyl)cyclohexane-4-carboxylic acid
Trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid
Trans-p-(Aminomethyl)cyclohexanecarboxylic
Transamin
Transamin (TN)
Transamlon
Trasamlon
UNII-6T84R30KC1
Ugurol
WLN: L6TJ AVQ D1Z -T
cis-4-(Aminomethyl)cyclohexanecarboxylic acid
cis-4-Aminomethylcyclohexane-1-carboxylic acid
cis-AMCHA
t-AMCHA
tranexamic acid
tranexmic acid
trans-1-Aminomethylcyclohexane-4-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-carboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid ester
trans-4-Aminomethylcyclohexane-1-carboxylic acid
trans-4-aminomethylcyclohexane-1-carboxylic acid
trans-Amcha
trans-Tranexamic acid
trans-p-(Aminomethyl)cyclohexanecarboxylic acid
2Antifibrinolytic AgentsPhase 4, Phase 3, Phase 2, Phase 1346
3HemostaticsPhase 4, Phase 3, Phase 2, Phase 11082
4CoagulantsPhase 4, Phase 3, Phase 2, Phase 11042
5Calcium, DietaryPhase 44678
6
EtoposideapprovedPhase 3116933419-42-036462
Synonyms:
(-)-Etoposide
121471-01-0
136598-18-0
201594-04-9
33419-42-0
35317-32-9
4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside
4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin ethylidene-.beta.-D-glucoside
4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin
4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside
4-Demethylepipodophyllotoxin-.beta.-D-ethylideneglucoside
51854-34-3
76576-58-4
9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-D)-1,3-dioxol-6(5ah)-one
AB00438905
AC1L1FN8
AC1L1VT3
AC1L6246
AC1NR4OG
AC1O4WGG
AC1O7M1N
AC1Q47JJ
Ambap33419-42-0
BPBio1_000673
BRD-K37798499-001-02-5
BSPBio_000611
Bio1_000489
Bio1_000978
Bio1_001467
C01576
CCRIS 2392
CHEBI:4911
CHEBI:588795
CHEMBL44657
CID11758093
CID284997
CID3310
CID36462
CID5284558
CID6419930
CID6610299
CPD000112002
D00125
DB00773
DEMETHY-EPIPODOPHYLLOTOXIN,ETHYLIDENE GLUCOSIDE,
Demethyl Epipodophyllotoxin Ethylidine Glucoside
Demethyl-epiodophyllotoxin ethylidene glucoside
Demethylepipodophyllotoxin-beta-D-ethylideneglucoside
E0675
E1383_SIGMA
EINECS 251-509-1
EPE
EPEG
ETOP
Epipodophyllotoxin
Epipodophyllotoxin VP-16213
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-.beta.-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-.beta.-D-glucopyranoside)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
Eposide
Eposin
Eposin, Vepesid, VP-16, Toposar, Etoposide
 
Etopol
Etopophos
Etopophos (phosphate salt)
Etoposid
Etoposide
Etoposide (JP15/USP/INN)
Etoposide (VP16)
Etoposide Phosphate
Etoposide [USAN:INN:BAN:JAN]
Etoposido
Etoposido [INN-Spanish]
Etoposidum
Etoposidum [INN-Latin]
Etosid
HMS1569O13
HMS2052N05
HMS2089F14
HSDB 6517
I06-0248
KBioSS_002410
LS-1214
Lastet
MLS000049957
MLS001074951
MLS001424283
MLS002153463
MLS002207239
MLS002222184
MolPort-003-983-431
MolPort-004-905-001
MolPort-004-955-161
NCGC00025056-02
NChemBio.2007.10-comp19
NK 171
NSC 141540
NSC-141540
NSC141540
Prestwick0_000396
Prestwick1_000396
Prestwick2_000396
Prestwick3_000396
Prestwick_211
S1225_Selleck
SAM001246880
SMR000112002
SPBio_002532
ST056353
Toposar
UNII-6PLQ3CP4P3
VP 16
VP 16 (pharmaceutical)
VP 16-213
VP 16213
VP-16
VP-16-213
VePESID (TN)
VePesid
Vepesid
Vepesid J
Vepeside
ZINC03830818
ZINC03938684
Zuyeyidal
etoposide
nchembio.573-comp8
nchembio873-comp2
trans-Etoposide
7
IsotretinoinapprovedPhase 31154759-48-25538, 5282379
Synonyms:
(13-cis)-Retinoate
(13-cis)-Retinoic acid
(13cis)-retinoic acid
(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
(2Z,4E6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
(7E,9E,11E,13Z)-retinoic acid
(7e,9e,11e,13Z)-Retinoic acid
13 Cis-Retinoic Acid
13 cis retinoic acid
13-RA
13-cis RA
13-cis retinoic acid
13-cis-Retinoate
13-cis-Retinoic acid
13-cis-Vitamin A acid
13-cis-Vitamin a acid
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-cis-4-trans-6-trans-8-trans-nonatetraenoic acid
4-09-00-02388 (Beilstein Handbook Reference)
4759-48-2
97950-17-9
AC-15388
AC1NQZZ4
Absorica
Accutane
Accutane (TN)
Ambap302-79-4
Amnesteem
BML2-E07
BPBio1_000080
BRD-K76723084-001-05-9
BRN 1885770
BSPBio_000072
BSPBio_001331
BSPBio_003345
CCRIS 4286
CHEBI:6067
CHEMBL547
CID5282379
CIP-Isotretinoin
CPD000471891
Claravis
Clarus
D00348
D015474
EINECS 225-296-0
EU-0101081
Epuris
HMS1361C13
HMS1568D14
HMS1791C13
HMS1921D08
HMS1989C13
HMS2092N07
HSDB 3929
IDI1_033801
Isotane
Isotretinoin
Isotretinoin (USP)
 
Isotretinoin Retinoic acid
Isotretinoin Zinc Salt, 13 cis Isomer
Isotretinoin Zinc Salt, 13-cis-Isomer
Isotretinoin [USAN:BAN:INN]
Isotretinoin [USAN:INN:BAN]
Isotretinoina
Isotretinoine
Isotretinoine [INN-French]
Isotretinoino
Isotretinoino [INN-Spanish]
Isotretinoinum
Isotretinoinum [INN-Latin]
Isotrex
LMPR01090021
LS-143465
Lopac0_001081
MLS001074662
MolPort-003-666-394
Myorisan
NCGC00094358-01
NCGC00094358-02
NCGC00094358-03
NCGC00094358-04
NCGC00094358-05
NCGC00094358-06
NCGC00094358-07
NCGC00094358-08
NCGC00094358-09
NCGC00094358-13
Neovitamin A acid
Neovitamin a acid
Prestwick2_000256
Prestwick3_000256
Prestwick_642
R 3255
R3255_SIGMA
Retinoate
Retinoic acid
Ro 4 3780
Ro 4-3780
Ro 43780
Ro-4-3780
Ro-43780
Roaccutan
Roaccutane
Roacutan
SAM002548955
SMR000471891
SPECTRUM1502013
Sotret
Sotret (TN)
Spectrum5_001795
Spectrum5_001937
Teriosal
UNII-EH28UP18IF
Zenatane
cis-RA
cis-Retinoate
cis-Retinoic acid
isotretinoino
8
Cyclophosphamideapproved, investigationalPhase 3264350-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
DB00531
 
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
9
Topotecanapproved, investigationalPhase 3330119413-54-660700
Synonyms:
(4S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
(S)-10-((Dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione
(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE
(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]-quinoline-3,14(4H,12H)-dione
(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
123948-87-8
9-Dimethylaminomethyl-10-hydroxycamptothecin
9-[(dimethylamino)Methyl]-10-hydroxy-(4S)-camptothecin
AC-11592
AC1L1TQZ
AC1Q6APZ
BSPBio_002348
C11158
C23H23N3O5
CCRIS 8163
CHEBI:107501
CHEBI:46035
CHEMBL84
CID60700
D08618
DB01030
HMS2090B20
HSCI1_000228
Hycamptamine
Hycamptin
Hycamtamine
Hycamtin
Hycamtin (TN)
LS-127395
MLS000759456
 
NCGC00178695-01
NCI60_004771
NCIStruc1_001659
NCIStruc2_001796
NChemBio.2007.10-comp24
NSC609699
SK&F-104864-A
SKF 104864
SKF-104864-A
SKF-S 104864
SMP2_000312
SMP2_000327
SMR000466344
TOPO
TOPOTECAN, HYCAMTIN
TPT
TTC
Topotecan
Topotecan (BAN)
Topotecan Hcl
Topotecan Hydrochloride
Topotecan Lactone
Topotecan Monohydrochloride, (S)-Isomer
Topotecan [INN:BAN]
Topotecan lactone
Topotecane
Topotecane [INN-French]
Topotecanum
Topotecanum [INN-Latin]
UNII-7M7YKX2N15
topotecan
10
Vincristineapproved, investigationalPhase 38632068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
11
CisplatinapprovedPhase 3254015663-27-184093, 441203, 2767
Synonyms:
(SP-4-1)-diamminedichloridoplatinum
(SP-4-1)-diamminedichloroplatinum
(SP-4-2)-diamminedichloridoplatinum
(SP-4-2)-diamminedichloroplatinum
Abiplatin
Biocisplatinum
Briplatin
CACP
CDDP
CHEBI:35852
CID441203
CPD0-1392
CPDC
CPDD
Carboquone
Cis Pt II
Cis-DDP
Cis-Diaminedichloroplatinum
Cis-Diamminedichloroplatinum
Cismaplat
Cisplatin
Cisplatine
Cisplatino
Cisplatinum
Cisplatyl
Citoplationo
DB00515
DDP
DDPT
Diamminedichloroplatinum
 
EU-0100918
Lederplatin
Neoplatin
Peyrone's chloride
Peyrone's salt
Plastin
Platamine
Platiblastin
Platidiam
Platinex
Platinol
Platinol-AQ
Platinol-aq
Platinoxan
Platinum Ammine Chloride
Platinum Ammonium Chloride
Platinum Diamine Dichloride
Randa
Trans-DDP
Trans-Diaminedichloroplatinum
Trans-Diamminedichloroplatinum
Trans-Dichlorodiammine Platinum
Trans-Platinumdiammine Dichloride
cis-DDP
cis-Diamminedichloroplatinum
cis-Dichlorodiammineplatinum(II)
cis-[PtCl2(NH3)2]
cis-diamminedichloridoplatinum(II)
cis-diamminedichloroplatinum(II)
nchembio773-comp1
trans-diamminedichloridoplatinum(II)
12
MelphalanapprovedPhase 3685148-82-34053, 460612
Synonyms:
(2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid
(2s)-2-amino-3-(4-[bis(2-chloroethyl)amino]phenyl)propanoic acid
148-82-3
3-(P-(Bis(2-chloroethyl)amino)phenyl)-L-alanine
3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine
3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine
3-P-(Di(2-chloroethyl)amino)-phenyl-L-alanine
3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine
3025 C.B.
3025 c.b
3223-07-2
4-(Bis(2-chloroethyl)amino)-L-phenylalanine
4-14-00-01689 (Beilstein Handbook Reference)
4-[Bis(2-chloroethyl)amino]-L-phenylalanine
4-[Bis-(2-chloroethyl)amino]-L-phenylalanine
AC1LA2OE
ALKERAN (TN)
AY3360000
Alanine Nitrogen Mustard
Alkeran
AmbotzHAA1563
At-290
BIDD:GT0044
BRD-K87827419-001-02-8
BRN 2816456
BSPBio_002407
C13H18Cl2N2O2
CB 3025
CB-3025
CCRIS 374
CHEBI:165415
CHEBI:28876
CHEMBL852
CID460612
D00369
DivK1c_000653
EINECS 205-726-3
HMS2090B09
HMS2091B16
HMS502A15
HSDB 3234
IDI1_000653
KBio1_000653
KBio2_000877
KBio2_003445
KBio2_006013
KBio3_001627
KBioGR_001284
KBioSS_000877
L-3-(P-(Bis(2-chloroethyl)amino)phenyl)alanine
L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine
L-3-(para-(Bis(2-chloroethyl)amino)phenyl)alanine
L-PAM
L-Phenylalanine mustard
L-Sarcolysin
L-Sarcolysine
L-Sarkolysin
LS-15868
LS-865
Levofalan
 
Levofolan
Levopholan
M2011_SIGMA
MELPHALAN (SEE ALSO TRANSGENIC MODEL EVALUATION (MELPHALAN))
MLS001333666
MLS002153368
Melfalan
Melfalano
Melfalano [INN-Spanish]
Melphalan (JP15/USP/INN)
Melphalan Hydrochloride
Melphalan [USAN:INN:BAN:JAN]
Melphalan hydrochloride
Melphalanum
Melphalanum [INN-Latin]
Mephalan
MolPort-003-665-535
NCGC00090757-01
NCGC00090757-02
NCGC00090757-03
NCI-C04853
NINDS_000653
NIOSH/AY3360000
NSC 241286
NSC 8806
NSC-8806
NSC241286
NSC8806
P-Di-(2-chloroethyl)amino-L-phenylalanine
P-L-Sarcolysin
P-N-Bis(2-chloroethyl)amino-L-phenylalanine
Phenylalanine mustard
Phenylalanine nitrogen mustard
Prestwick_1006
RCRA waste no. U150
Rcra waste number U150
SK-15673
SMP2_000174
SMR000058720
SPBio_000287
SPECTRUM1500382
Sarcolysine
Sarkolysin
Spectrum2_000074
Spectrum3_000684
Spectrum4_000882
Spectrum5_001601
Spectrum_000397
TL8001065
TRANSGENIC LEP (MELPHALAN) (SEE ALSO MELPHALAN)
TRANSGENIC MODEL EVALUATION (MELPHALAN)
UNII-Q41OR9510P
melphalan
p-Bis(beta-chloroethyl)aminophenylalanine
p-Di-(2-chloroethyl)amino-L-phenylalanine
p-L-Sarcolysin
p-L-sarcolysine
p-N,N-bis(2-chloroethyl)amino-L-phenylalanine
p-N-Bis(2-chloroethyl)amino-L-phenylalanine
p-N-Di(chloroethyl)aminophenylalanine
p-N-di(chloroethyl)aminophenylala nine
phenylalanine nitrogen mu stard
13
MechlorethamineapprovedPhase 330951-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
KBioGR_001448
 
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethamine hydrochloride
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
Valchlor
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
β,β'-dichlorodiethyl-N-methylamine
14
Doxorubicinapproved, investigationalPhase 3158223214-92-831703
Synonyms:
(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
(8S-cis)-10-((3-amino-2,3,6-Trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
111266-55-8
14-Hydroxydaunomycin
14-Hydroxydaunorubicine
14-hydroxydaunomycin
14-hydroxydaunorubicine
23214-92-8
23257-17-2
24385-08-8
25311-50-6
25316-40-9
25316-40-9 (hydrochloride)
29042-30-6
AC1L1M5T
AC1Q29OJ
ADM
ADR
Adriablastin
Adriacin (hydrochloride salt)
Adriamycin
Adriamycin PFS
Adriamycin PFS (hydrochloride salt)
Adriamycin RDF
Adriamycin RDF (hydrochloride salt)
Adriamycin Semiquinone
Adriamycin semiquinone
Adriblas tina
Adriblastin
Adriblastina
Adriblastina (TN)
Adriblastina (hydrochloride salt)
Aerosolized Doxorubicin
BPBio1_000502
BRD-K92093830-003-04-3
BSPBio_000456
BSPBio_001031
C01661
C27H29NO11
CCRIS 739
CHEBI:28748
CHEMBL179
CID31703
Caelyx
Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74
Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120
D03899
DB00997
DM2
DOX-SL
Doxil
Doxo
Doxorubicin
Doxorubicin (USAN/INN)
Doxorubicin HCl
 
Doxorubicin Hydrochloride
Doxorubicin [USAN:INN:BAN]
Doxorubicin citrate
Doxorubicin hydrochloride (hydrochloride salt)
Doxorubicin-P4/D10
Doxorubicin-P4/D10 conjugate
Doxorubicin-hLL1
Doxorubicin-hLL1 conjugate
Doxorubicina
Doxorubicina [INN-Spanish]
Doxorubicine
Doxorubicine [INN-French]
Doxorubicinum
Doxorubicinum [INN-Latin]
EINECS 245-495-6
FI 106
Farmablastina (hydrochloride salt)
HMS2089H06
HSDB 3070
Hydroxydaunomycin hydrochlor ide (hydrochloride salt)
Hydroxydaunomycin hydrochloride (hydrochloride salt)
Hydroxydaunorubicin
Hydroxydaunorubicin hydrochloride (hydrochloride salt)
JT9100000
LMPK13050001
LS-1029
LS-165655
MLS000759533
Myocet
NCI-C01514
NChemBio.2007.10-comp13
NDC 38242-874
NIOSH/JT9100000
NSC 123127
Prestwick0_000438
Prestwick1_000438
Prestwick2_000438
Prestwick3_000438
Probes1_000151
Probes2_000129
RDF Rubex
Resmycin
Rubex
Rubex (hydrochloride salt)
SMP1_000106
SPBio_002395
TLC D-99
ThermoDox
Triferric doxorubicin
UNII-80168379AG
adiblastine (hydrochloride salt)
adr iablatina (hydrochloride salt)
adriablastine (hydrochloride salt)
adriablatina (hydrochloride salt)
adriblatina (hydrochloride salt)
doxorubicin
nchembio809-comp5
15
CarboplatinapprovedPhase 3188541575-94-410339178, 498142, 38904
Synonyms:
(SP-4-2)-diammine[cyclobutane-1,1-dicarboxylato(2-)-kappa(2)O,O']platinum
/h1-3H2,(H,7,8)(H,9,10)
/q
1,1-Cyclobutanedicarboxylate diammine platinum (II)
1,1-Cyclobutanedicarboxylate diammine platinum(II)
2*-1
2*1H2
41575-94-4
70903-55-8
AC-1457
AC1L8I6U
Ambap41575-94-4
BSPBio_003145
C 2538
C2043
C2538_SIGMA
C6H10N2O4Pt
CBDCA
CCRIS 3404
CHEBI:31355
CHEMBL1351
CHEMBL288376
CID10339178
CID2567
CID38904
CID426756
CID498142
CID5352133
CID6398587
CID6603770
Carbopaltin
Carboplatin
Carboplatin (JAN/USP/INN)
Carboplatin (USAN)
Carboplatin [USAN:INN:BAN:JAN]
Carboplatine
Carboplatine [French]
Carboplatino
Carboplatino [Spanish]
Carboplatinum
Carboplatinum [Latin]
Cbdca
Cyclobutane-1,1-dicarboxylate
D01363
DB00958
Diammine(1,1-cyclobutanedicarboxylato)platinum (II)
Diammine(cyclobutane-1,1-dicarboxylato(2-)-O,O')platinum
Diammine-1,1-cyclobutane dicarboxylate platinum II
DivK1c_000892
EINECS 255-446-0
EU-0100230
Ercar
HMS1921J16
HMS2090M05
HMS2092B22
HMS502M14
HSDB 6957
I14-2390
IDI1_000892
IUPAC: Azane
InChI=1/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6
 
JM 8
JM-8
KBio1_000892
KBio2_002009
KBio2_004577
KBio2_007145
KBio3_002645
KBioGR_000713
KBioSS_002009
LS-117689
Lopac-C-2538
Lopac0_000230
MolPort-003-665-501
MolPort-003-845-609
NCGC00015223-01
NCGC00093695-01
NCGC00094961-01
NCGC00094961-02
NCGC00094961-03
NCGC00162099-01
NCGC00162099-02
NCGC00167800-01
NCGC00178242-01
NINDS_000892
NSC 201345
NSC 241240
NSC-241240
NSC201345
NSC241240
Paraplatin
Paraplatin (TN)
Paraplatin, Carboplatin
Paraplatin-AQ
Platinum(+2) Cation
Platinum(II), (1, 1-cyclobutanedicar
Platinum, diammine(1,1-cyclobutanedicarboxylato(2-)-O,O')-, (SP-4-2)
Platinum, {diammine[1,1-cyclobut
S1215_Selleck
SPBio_000716
SPECTRUM1502106
Spectrum2_000898
Spectrum3_001503
Spectrum4_000337
Spectrum5_001094
Spectrum_001529
UNII-BG3F62OND5
azanide
carboplatin
cis -Diammine[1,1-cyclobutane-dicarboxylato] platinum
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II)
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(ii)
cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II)
cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II)
cis-Diammine(1,1-cyclobutanedicarboxylato) platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
cis-Diammine(cyclobutanedicarboxylato)platinum II
cyclobutane-1,1-dicarboxylic acid
diammine[cyclobutane-1,1-dicarboxylato(2-)-k2O1,O1]platinum
nchembio.573-comp10
nchembio773-comp2
nchembio873-comp3
platinum(2+)
16
Tretinoinapproved, investigational, nutraceuticalPhase 3210302-79-45538, 444795
Synonyms:
(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate
(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
(all-e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
.beta.-Retinoic acid
13497-05-7 (hydrochloride salt)
15-Apo-beta-caroten-15-oic acid
187175-63-9
1n4h
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ecl)
302-79-4
5300-03-8
56573-65-0
7005-78-9
9(Z)-Retinoic acid
9-cis-RA
A-Acido (Argentina)
A-Vitaminsyre
A-Vitaminsyre [Denmark]
AC-6824
AC1L9GWO
AC1Q1J2J
AGN 100335
AGN 192013
AKOS000280845
ALRT 1057
AT-RA
ATRA
Aberel
Aberela
Aberela [Norway]
Accutane Roche
Acid A Vit (Belgium, Netherlands)
Acid, Retinoic
Acid, Vitamin A
Acid, all-trans-Retinoic
Acid, beta-all-trans-Retinoic
Acid, trans-Retinoic
Acide retinoique (French)
Acide retinoique (French) (DSL)
Acide retinoique (french) (dsl)
Acnavit
Acnavit [Denmark]
Airol
Aknefug
Aknoten
Alitretinoin
All Trans Retinoic Acid
All Trans-Retinoic Acid
All-(E)-Retinoate
All-(E)-Retinoic acid
All-trans Retinoic Acid
All-trans-Retinoate
All-trans-Retinoic acid
All-trans-Tretinoin
All-trans-Vitamin A acid
All-trans-Vitamin A1 acid
Alltrans-retinoic acid
Amnesteem
Atra-IV
Atragen
Atralin
Avita
Avita (TN)
Avita Gel
Avitoin
Avitoin [Norway]
BAL4079
BIDD:GT0483
BIDD:PXR0081
BML2-E05
BPBio1_000082
BRN 2057223
BSPBio_000074
BSPBio_001500
Betarretin
C00777
CCRIS 3294
CCRIS 7098
CHEBI:15367
CHEMBL38
CID444795
CPD000058245
Claravis
Cordes VAS [Germany]
Cordes vas
D00094
D014212
DB00523
DB00755
DB00982
Dermairol
EINECS 206-129-0
EU-0101061
Effederm
Effederm [France]
Epi-aberel
Eudyna
HMS1361K22
HMS1568D16
HMS1791K22
HMS1921D14
HMS1989K22
HMS2089D20
HMS2092N11
HMS502N05
HSDB 2169
HSDB 7186
I04-0008
I14-2351
IDI1_000903
IDI1_033970
Isotretinoin Retinoic acid
L000833
LGD 100057
LMPR01090019
LS-1154
Lopac0_001061
Lsotretinoin
MLS000028588
MLS001076515
MLS002207234
MLS002222211
MolPort-000-883-857
NCGC00017280-06
NCGC00017280-17
NCGC00021808-04
 
NCGC00021808-05
NCGC00021808-06
NCGC00021808-07
NCGC00021808-09
NCGC00021808-14
NCGC00021808-15
NSC 122758
NSC-122758
NSC122758
Nexret
Obagi
PDT-002-002
Panretin Gel
Panretyn
Potassium Salt, Tretinoin
Prestwick2_000257
Prestwick3_000257
Prestwick_424
R 2625
R0064
R2625_SIGMA
REA
RETINOIC ACID, ALL TRANS
RETINOIC acid
Refissa
Renova
Renova (TN)
Retacnyl
Retin A
Retin A (TN)
Retin-A
Retin-A Micro
Retin-a
Retin-a Micro
Retinoate
Retinoic acid
Retinoic acid, all-trans- (8CI)
Retinova
Retionic Acid
Retionic acid
Retisol-A
Retisol-a
Ro 1-5488
S1653_Selleck
SAM002264647
SMR000058245
SPECTRUM1502016
SR-01000000239
SR-01000000239-14
ST057075
Salt, Tretinoin Potassium
Salt, Tretinoin Sodium
Salt, Tretinoin Zinc
Sodium Salt, Tretinoin
Solage
Sotret
Spectrum5_001746
Spectrum5_001933
Stieva-A
Stieva-a
Stieva-a Forte
TRETINON
Tretin M
Tretin m
Tretin-x
Tretin.x
Tretinoin
Tretinoin (JAN/USP/INN)
Tretinoin (TN)
Tretinoin 0.1% cream or placebo
Tretinoin Cream
Tretinoin Gel Microsphere
Tretinoin Potassium Salt
Tretinoin Sodium Salt
Tretinoin Zinc Salt
Tretinoin [USAN:INN:BAN]
Tretinoin/All-Trans Retinoic Acid
Tretinoina
Tretinoina [INN-Spanish]
Tretinoine
Tretinoine (French)
Tretinoine (french) (einecs)
Tretinoine [INN-French]
Tretinoino
Tretinoino [INN-Spanish]
Tretinoinum
Tretinoinum [INN-Latin]
Tretinx
Tri-Luma
Trétinoïne
UNII-1UA8E65KDZ
UNII-5688UTC01R
UPCMLD-DP097
Vesanoid
Vesanoid (TN)
Vesanoid, Airol, Renova, Atralin, Retin-A, Avita, Tretinoin
Vesnaroid
Vitamin A acid
Vitinoin
WLN: L6UTJ A1 B1U1Y1 & U2U1Y1 & U1VQ C1 C1
WLN: L6UTJ A1 B1U1Y1&U2U1Y1&U1VQ C1 C1
Zinc Salt, Tretinoin
[3H]Retinoic acid
all trans-Retinoic acid
all-(E)-Retinoic acid
all-(e)-Retinoic acid
all-trans-Retinoic acid
all-trans-Tretinoin
all-trans-Vitamin A acid
all-trans-Vitamin A1 acid
all-trans-Vitamin a acid
all-trans-Vitamin a1 acid
all-trans-b-Retinoic acid
all-trans-beta-Retinoic acid
b-Retinoic acid
beta all trans Retinoic Acid
beta-Ra
beta-Retinoate
beta-Retinoic Acid
beta-Retinoic acid
beta-all-trans-Retinoic acid
bmse000562
nchembio.154-comp2
trans Retinoic Acid
trans-Retinoate
trans-Retinoic acid
tretinoin
tretinoin liposome
tretinoine (French) (EINECS)
17
DoxilApproved June 1999Phase 3158231703
Synonyms:
Dox-SL
Doxil
 
Evacet
LipoDox
Pegylated Liposomal Doxorubicin Hydrochloride
liposomal doxorubicin
18Anti-Bacterial AgentsPhase 39140
19Adjuvants, ImmunologicPhase 31783
20topoisomerase I inhibitorsPhase 31131
21Alkylating AgentsPhase 33582
22lenograstimPhase 31134
23Tubulin ModulatorsPhase 34279
24Topoisomerase InhibitorsPhase 34081
25Antibiotics, AntitubercularPhase 35971
26Antineoplastic Agents, PhytogenicPhase 34294
27Dermatologic AgentsPhase 34555
28Antirheumatic AgentsPhase 38496
29Antimitotic AgentsPhase 34296
30Antineoplastic Agents, AlkylatingPhase 33406
31Etoposide phosphatePhase 31169
32Immunosuppressive AgentsPhase 310422
33Immunologic FactorsPhase 318483
34phenylalanineNutraceuticalPhase 3145
35
Aminocaproic Acidapproved, investigationalPhase 2, Phase 12660-32-2564
Synonyms:
.epsilon. S
.epsilon.-Aminocaproic acid
.epsilon.-Aminohexanoic acid
.epsilon.-Leucine
.epsilon.-Norleucine
.omega.-Aminocaproic acid
.omega.-Aminohexanoic acid
1319-82-0
177 J.D
177 J.D.
1cea
3kiv
6 Aminocaproic Acid
6 Aminohexanoic Acid
6-Amino-Hexanoate
6-Amino-Hexanoic acid
6-Amino-N-hexanoate
6-Amino-N-hexanoic acid
6-Amino-n-hexanoic acid
6-Aminocaproate
6-Aminocaproic acid
6-Aminohexanoate
6-Aminohexanoic acid
6-amino-hexanoic acid
6-amino-n-caproate
6-amino-n-caproic acid
6-aminohexanoate
6-aminohexanoic acid
60-32-2
87867-96-7
93208-38-9
A 7824
A0312
A2504_SIGMA
A7824_SIGMA
AB00051911
AC-035
AC1L19IP
AC1Q54EY
ACS
AI3-14512
AKOS000118734
AMICAR
AMINOCAPROIC
Acepramin
Acepramine
Acid, 6-Aminocaproic
Acid, 6-Aminohexanoic
Acid, epsilon-Aminocaproic
Acide aminocaproique
Acide aminocaproique [French]
Acide aminocaproique [INN-French]
Acide aminocaproque
Acide aminocaproïque
Acido aminocaproico
Acido aminocaproico [DCIT,Spanish]
Acido aminocaproico [INN-Spanish]
Acidum Aminocaproicum
Acidum aminocaproicum
Acidum aminocaproicum [INN-Latin]
Acidum aminocaproicum [Latin]
Acikaprin
Afibrin
Ahx
Amicar
Amicar (TN)
Amicar, |A-amino caproic acid, |A-Ahx, 6-aminohexanoic acid, Aminocaproic acid
Amikar
Aminocaproate
Aminocaproic
Aminocaproic Acid
Aminocaproic Acid In Plastic Container
Aminocaproic Acids
Aminocaproic acid
Aminocaproic acid (USP)
Aminocaproic acid (USP/INN)
Aminocaproic acid [USAN:BAN:INN]
Aminocaproic acid [USAN:INN:BAN]
Aminocapronsäure
Aminohexanoic acid
Aminokapron
Atsemin
BIDD:GT0162
BPBio1_001056
BRN 0906872
BSPBio_000960
C02378
C3BDD377-8F43-4BEC-900A-D5850050BA82
C6H13NO2
CAS-60-32-2
CBDivE_004370
CCRIS 7706
CHEBI:16586
CHEMBL1046
CID564
CL 10304
CL-10304
CY 116
CY-116
CY116
Caplamin
Capracid
Capralense
Capramol
Capranol
Caproamin
Caprocid
Caprolisin
D00160
D015119
DB00513
DB04134
DivK1c_000551
EACA
EACS
EINECS 200-469-3
EPSILON-AMINOCAPROIC ACID
EU-0100082
Eaca
Eaca kabi
 
Epsamon
Epsicaprom
Epsicapron
Epsikapron
Epsilcapramin
Epsilcapramine
Epsillon-Aminocaproate
Epsillon-Aminocaproic acid
Epsillon-Aminocaproic acid' Epsilcapramin
Epsilon S
Epsilon-Aminocaproic Acid
Epsilon-Aminocapronsaeure
Epsilon-aminocapronzuur
H-6-Ahx-OH
H-EAhx-OH
H-epsilon-Acp-OH
HEXANOIC ACID,6-AMINO
HMS1570P22
HMS1920C07
HMS2091I07
HMS501L13
HSDB 3005
Hemocaprol
Hemopar
Hepin
IDI1_000551
InChI=1/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9
Ipsilon
JD 177
KBio1_000551
KBio2_000398
KBio2_002966
KBio2_005534
KBioGR_000586
KBioSS_000398
Kyselina omega-aminokapronova
Kyselina omega-aminokapronova [Czech]
LMFA01100035
LS-7191
Lopac-A-7824
Lopac0_000082
MLS001335991
MLS002695931
MolPort-001-779-881
NCGC00015092-01
NCGC00015092-02
NCGC00015092-03
NCGC00015092-07
NCGC00093587-01
NCGC00093587-02
NCGC00093587-03
NCGC00093587-04
NINDS_000551
NSC 26154
NSC 400230
NSC-26154
NSC212532
NSC26154
NSC400230
Omega-Aminocaproate
Omega-Aminocaproic acid
Omega-Aminohexanoate
Omega-Aminohexanoic acid
Prestwick0_000960
Prestwick1_000960
Prestwick2_000960
Prestwick3_000960
Respramin
S04-0132
S1671_Selleck
SMR000059162
SPBio_000202
SPBio_003109
SPECTRUM1500114
STK246894
Spectrum2_000131
Spectrum4_000143
Spectrum5_000780
Spectrum_000038
TL8003819
UNII-U6F3787206
WLN: Z5VQ
Z
acide aminocaproque
amicar
bmse000394
e-Amino-N-hexanoate
e-Amino-N-hexanoic acid
e-Aminocaproate
e-Aminocaproic acid
e-Aminocaproic acid USP
e-Aminohexanoate
e-Aminohexanoic acid
e-Leucine
e-Norleucine
epsilcapramine
epsilon Aminocaproic Acid
epsilon S
epsilon-Ahx
epsilon-Amino-N-hexanoate
epsilon-Amino-N-hexanoic acid
epsilon-Amino-n-caproic acid
epsilon-Amino-n-hexanoic acid
epsilon-Aminocaproate
epsilon-Aminocaproic acid
epsilon-Aminocaproic acid (JAN)
epsilon-Aminocaproic acid USP
epsilon-Aminohexanoate
epsilon-Aminohexanoic acid
epsilon-Leucine
epsilon-Norleucine
epsilon-S
epsilon-aminocaproate
nchembio.104-comp21
nchembio.2007.30-comp14
omega-Aminocaproic acid
omega-Aminohexanoic acid
w-Aminocaproate
w-Aminocaproic acid
w-Aminohexanoate
w-Aminohexanoic acid
Ácido aminocapróico
36Peripheral Nervous System Agents18510
37Analgesics9358

Interventional clinical trials:

(show all 23)
idNameStatusNCT IDPhase
1The Efficacy and Population Pharmacokinetics of Tranexamic Acid for Craniosynostosis SurgeryRecruitingNCT02188576Phase 4
2Tranexamic Acid for Craniofacial SurgeryTerminatedNCT00722436Phase 4
3Comparison of Allogenix Plus Demineralized Bone Matrix and Autogenous Bone Dust Versus Autogenous Bone Dust Alone in Ossification of Small Calvarial Defects, a Pilot Study.WithdrawnNCT01006148Phase 4
4Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With NeuroblastomaCompletedNCT00004188Phase 3
5Blood Loss and Transfusion Requirement in Infants Treated With Tranexamic AcidRecruitingNCT01094977Phase 3
6Efficacy of Amicar for Children Having Craniofacial SurgeryRecruitingNCT02229968Phase 2
7Amicar Pharmacokinetics of Children Having Craniofacial SurgeryCompletedNCT00912119Phase 1
8Genetic Analysis of Craniosynostosis, Philadelphia TypeCompletedNCT00367796
9Effect of Tranexamic Acid Based on Pharmacokinetics in Pediatric Patients Undergoing Craniosynostosis Surgery: Randomized Controlled TrialCompletedNCT02180321
10Nautilus: Dynamic Craniotomy; New Surgical Technique and Preliminary ResultsCompletedNCT01672619
11Child and Infant Learning ProjectCompletedNCT00077831
12Genetic Analysis of Craniofrontonasal SyndromeCompletedNCT00339846
13Osteogenic Profiling of Tissue From Children With CraniosynostosisRecruitingNCT00773643
14Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)RecruitingNCT00106977
15MRI for Non-invasive Evaluation of Brain StressRecruitingNCT01898650
16Irradiated Blood Versus Non Irradiated Blood Transfusions in Craniosynostosis RepairRecruitingNCT02483702
17Qualitative and Quantitative Study Which Aims to Determine the Specifics of the Announcement for the Diagnosis of Patients With Craniosynostosis and Their Parents to Better Support Them in Their CareActive, not recruitingNCT02287805
18National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular ConditionsActive, not recruitingNCT01322165
19Non-invasive Epicutaneous Transfontanel Intracranial Pressure Monitoring in Children Under the Age of One: a Novel TechniqueEnrolling by invitationNCT02775669
20Detection and Quantification of Neonatal Intraventricular HemorrhageEnrolling by invitationNCT01899651
21The Effect of Gender on the Consumption of Pain Medication in Infants Undergoing Craniosynostosis Repair or Untethering of Cord in ITUNot yet recruitingNCT01996163
22Hanger Helmet StudyNot yet recruitingNCT02561728
23Endoscopic Treatment for Isolated, Single Suture CraniosynostosisWithdrawnNCT00769847

Search NIH Clinical Center for Craniosynostosis


Cochrane evidence based reviews: craniosynostoses

Genetic Tests for Craniosynostosis

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Anatomical Context for Craniosynostosis

About this section

MalaCards organs/tissues related to Craniosynostosis:

33
Bone, Brain, Thyroid, Endothelial, Lung, Breast, Prostate

FMA organs/tissues related to Craniosynostosis:

16
Skull

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Craniosynostosis:
id TissueAnatomical CompartmentCell Relevance
1 BoneRostral SuturesFusing Suture Cells Affected by disease
2 BoneRostral SuturesPresumptive Suture Cells Affected by disease
3 BoneFacial SuturesPresumptive Suture Cells Affected by disease
4 BoneFacial SuturesSuture Cells Affected by disease
5 BoneRostral SuturesSuture Cells Affected by disease

Animal Models for Craniosynostosis or affiliated genes

About this section

MGI Mouse Phenotypes related to Craniosynostosis:

38 (show all 22)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.4FGF8, FGFR1, FGFR2, FGFR3, NOG, PHEX
2MP:00053797.8EFNB1, FGF8, FGFR1, FGFR2, MSX2, NOG
3MP:00053697.8ALX4, FGF8, FGFR1, FGFR2, MSX2, NOG
4MP:00053867.8ALX4, FGF8, FGFR1, FGFR2, FGFR3, MSX2
5MP:00053857.6ERF, FGF8, FGFR1, FGFR2, MSX2, NOG
6MP:00053917.6ALX4, EFNB1, FGF8, FGFR1, FGFR2, FGFR3
7MP:00053777.6EFNB1, FGF8, FGFR1, FGFR2, FGFR3, MSX2
8MP:00028737.5ALX4, ERF, FGF8, FGFR1, FGFR2, FGFR3
9MP:00053887.4ALX4, EFNB1, FGF8, FGFR2, FGFR3, NELL1
10MP:00107717.3ALX4, EFNB1, FGFR1, FGFR2, FGFR3, MSX2
11MP:00053877.0EFNB1, FGF8, FGFR1, FGFR2, FGFR3, MSX2
12MP:00053716.8ALX4, EFNB1, FGF8, FGFR1, FGFR2, FGFR3
13MP:00053806.7ALX4, EFNB1, ERF, FGF8, FGFR1, FGFR2
14MP:00053976.6EFNB1, ERF, FGF8, FGFR1, FGFR2, FGFR3
15MP:00053846.3EFNB1, ERF, FGF8, FGFR1, FGFR2, FGFR3
16MP:00053816.1ALX4, EFNB1, FGF8, FGFR1, FGFR2, FGFR3
17MP:00036315.9ALX4, EFNB1, ERF, FGF8, FGFR1, FGFR2
18MP:00053825.9ALX4, EFNB1, ERF, FGF8, FGFR1, FGFR2
19MP:00053905.0ALX4, EFNB1, ERF, FGF8, FGFR1, FGFR2
20MP:00107684.9ALX4, EFNB1, ERF, FGF8, FGFR1, FGFR2
21MP:00053784.9ALX4, EFNB1, ERF, FGF8, FGFR1, FGFR2

Publications for Craniosynostosis

About this section

Articles related to Craniosynostosis:

(show top 50)    (show all 733)
idTitleAuthorsYear
1
Tricky typhus ticks two: A report of two sisters from North India presenting with acute respiratory distress syndrome due to scrub typhus. (27080784)
2016
2
Epigenetic modifications in cutaneous malignant melanoma: EZH2, H3K4me2, and H3K27me3 immunohistochemical expression is enhanced at the invasion front of the tumor. (25614949)
2015
3
Acute tongue swelling, the only initial manifestation of carotid artery dissection: a case report with differentiation of clinical picture. (25463346)
2015
4
PPARD +294C overrepresentation in general and long-lived population in China Bama longevity area and unique relationships between PPARD +294T/C polymorphism and serum lipid profiles. (25873088)
2015
5
Rho-kinase signaling controls nucleocytoplasmic shuttling of class IIa histone deacetylase (HDAC7) and transcriptional activation of orphan nuclear receptor NR4A1. (25511694)
2015
6
Acute Ischemic Stroke: Time, Penumbra, and Reperfusion. (24399376)
2014
7
The rs9939609 gene variant in FTO modified the metabolic response of weight loss after a 3-month intervention with a hypocaloric diet. (23138007)
2013
8
Long-term evaluation of radiation-induced optic neuropathy after single-fraction stereotactic radiosurgery. (24074926)
2013
9
Papillary cystadenocarcinoma of the mammary gland with metastases to the gastrointestinal tract in a Himalayan brown bear (Ursus arctos). (23805565)
2013
10
Effect of down-regulated transcriptional repressor ZEB1 on the epithelial-mesenchymal transition of ovarian cancer cells. (24257549)
2013
11
Bilateral submandibular gland aplasia with hypertrophy of the sublingual glands of a patient with a cleft lip and palate: case report. (24036837)
2013
12
Multimodality imaging of a Gerbode defect. (22753537)
2012
13
The antiepileptic drug valproic acid restores T cell homeostasis and ameliorates pathogenesis of experimental autoimmune encephalomyelitis. (22733814)
2012
14
A20 and CYLD do not share significant overlapping functions during B cell development and activation. (23002441)
2012
15
Localized Langerhans cell histiocytosis of the stomach treated by endoscopic submucosal dissection. (21837608)
2011
16
2-(-2-benzofuranyl)-2-imidazoline induces Bcl-2 expression and provides neuroprotection against transient cerebral ischemia in rats. (20840843)
2010
17
Association of brain-derived neurotrophic factor genetic Val66Met polymorphism with severity of depression, efficacy of fluoxetine and its side effects in Chinese major depressive patients. (20016225)
2010
18
Reduction of brain infarction induced by a transient brain ischemia in mdr1a knockout mice. (19277863)
2009
19
Generation of an indestructible cyclin B1 by caspase-6-dependent cleavage during mitotic catastrophe. (18820706)
2009
20
Cochlear implantation results in patients with Kearns-Sayre syndrome. (18382375)
2008
21
Overexpression of p101 activates PI3Kgamma signaling in T cells and contributes to cell survival. (17486067)
2007
22
Comparison of African-American patients with systolic heart failure versus preserved ejection fraction. (16950190)
2006
23
HIV-1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses. (16001085)
2005
24
Ethanol-induced iNOS and COX-2 expression in cultured astrocytes via NF-kappa B. (15094475)
2004
25
Tuberous sclerosis complex: from Drosophila to human disease. (15102439)
2004
26
Activated eosinophils infiltrate MCF-7 breast multicellular tumor spheroids. (12680196)
2003
27
Diet, body weight, and colorectal cancer: a summary of the epidemiologic evidence. (12737716)
2003
28
Multiple biomarkers study in painters in a shipyard in Korea. (12972061)
2003
29
Characterization of the 5'-flanking region of the human PTK6 gene. (11997104)
2002
30
Craniofacial surgery for giant frontonasal encephalocele in a neonate. (12383426)
2002
31
Modulation of selenoprotein P expression by TGF-beta(1) is mediated by Smad proteins. (11568450)
2001
32
Plasma norepinephrine and atrial natriuretic peptide in heart failure: influence of felodipine in the third Vasodilator Heart Failure Trial. V-HeFT III investigators. (10908083)
2000
33
Colocalization of thrombin, PAI-1, and vitronectin in the atherosclerotic vessel wall: A potential regulatory mechanism of thrombin activity by PAI-1/vitronectin complexes. (10764685)
2000
34
Interleukin 1 and interleukin 1beta converting enzyme (caspase 1) expression in the human colonic epithelial barrier. Caspase 1 downregulation in colon cancer. (10403737)
1999
35
The impact of HIV infection on Mycobacterium kansasii disease in South African gold miners. (10390373)
1999
36
Identification of a putative effector protein for rab11 that participates in transferrin recycling. (10077598)
1999
37
HbF synthesis during stress erythropoiesis as determined by gamma-mRNA/non-alpha-mRNA quantification. (10231865)
1999
38
Equus caballus gelsolin--cDNA sequence and protein structural implications. (9490033)
1998
39
Localization of a molecular form of interferon-regulated RNase L in the cytoskeleton. (9660242)
1998
40
Intranasal meningoencephalocele and the use of fibrin glue. (9248140)
1997
41
Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6. (9311994)
1997
42
Induction of urinary interleukin-1 (IL-1), IL-2, IL-6, and tumour necrosis factor during intravesical immunotherapy with bacillus Calmette-GuAcrin in superficial bladder cancer. (1540977)
1992
43
Overexpression of c-myc, c-fos and Harvey ras oncogenes in renal cancers--analysis at the messenger RNA levels]. (1779495)
1991
44
Monovalent cation and amiloride analog modulation of adrenergic ligand binding to the unglycosylated alpha 2B-adrenergic receptor subtype. (1850091)
1991
45
Elimination of asbestosis. (651728)
1978
46
Congenital epulis. (4340239)
1972
47
The problem of hepatic coma. (13252383)
1955
48
49
50

Variations for Craniosynostosis

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Expression for genes affiliated with Craniosynostosis

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Search GEO for disease gene expression data for Craniosynostosis.

Pathways for genes affiliated with Craniosynostosis

About this section

Pathways related to Craniosynostosis according to GeneCards Suite gene sharing:

(show all 27)
idSuper pathwaysScoreTop Affiliating Genes
19.8FGFR1, NELL1
29.7FGFR1, FGFR2, FGFR3
39.7FGFR1, FGFR2, FGFR3
49.7FGFR1, FGFR2, FGFR3
59.6FGF8, FGFR1, FGFR3
6
Show member pathways
9.4FGF8, FGFR1, FGFR2, FGFR3
7
Show member pathways
9.4FGF8, FGFR1, FGFR2, FGFR3
89.4FGF8, FGFR1, FGFR2, FGFR3
9
Show member pathways
9.4FGF8, FGFR1, FGFR2, FGFR3
10
Show member pathways
9.4FGF8, FGFR1, FGFR2, FGFR3
11
Show member pathways
9.4FGF8, FGFR1, FGFR2, FGFR3
12
Show member pathways
9.4FGF8, FGFR1, FGFR2, FGFR3
13
Show member pathways
9.4FGF8, FGFR1, FGFR2, FGFR3
14
Show member pathways
9.3FGFR1, FGFR2, FGFR3, NELL1
15
Show member pathways
9.1FGFR1, FGFR2, FGFR3, TGFBR1
169.1FGF8, MSX2, NOG
178.9FGF8, FGFR1, FGFR2, FGFR3, MSX2, TWIST1
188.7FGF8, FGFR1, FGFR2, FGFR3, TGFBR1
19
Show member pathways
8.7FGF8, FGFR1, FGFR2, FGFR3, TGFBR1
208.7FGF8, FGFR1, FGFR2, FGFR3, TGFBR1
21
Show member pathways
8.5FGFR2, NOG, TCF12, TGFBR1
22
Show member pathways
8.3FGF8, FGFR1, FGFR2, FGFR3, NELL1, TGFBR1
23
Show member pathways
8.3FGF8, FGFR1, FGFR2, FGFR3, NELL1, TGFBR1
24
Show member pathways
8.3FGF8, FGFR1, FGFR2, FGFR3, NELL1, TGFBR1
25
Show member pathways
8.1FGF8, FGFR1, FGFR2, FGFR3, IL11RA, TCF12
26
Show member pathways
8.1EFNB1, FGF8, FGFR1, FGFR2, FGFR3, NELL1
27
Show member pathways
7.7FGF8, FGFR1, FGFR2, FGFR3, IL11RA, NELL1

GO Terms for genes affiliated with Craniosynostosis

About this section

Biological processes related to Craniosynostosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 53)
idNameGO IDScoreTop Affiliating Genes
1endochondral bone growthGO:000341610.8FGFR3, MSX2
2fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex developmentGO:003560710.7FGFR1, FGFR2
3epithelial to mesenchymal transition involved in endocardial cushion formationGO:000319810.6FGF8, MSX2
4lung-associated mesenchyme developmentGO:006048410.6FGFR1, FGFR2
5organ inductionGO:000175910.5FGF8, FGFR1
6positive regulation of cell cycleGO:004578710.5FGFR1, FGFR2
7limb morphogenesisGO:003510810.5ALX4, FGF8
8central nervous system neuron developmentGO:002195410.5FGF8, FGFR1
9generation of neuronsGO:004869910.5FGF8, FGFR1
10positive regulation of cardiac muscle cell proliferationGO:006004510.5FGFR1, FGFR2
11outflow tract septum morphogenesisGO:000314810.5FGF8, MSX2
12signal transduction involved in regulation of gene expressionGO:002301910.4FGF8, MSX2
13otic vesicle formationGO:003091610.4FGF8, FGFR2
14positive regulation of phospholipase activityGO:001051810.3FGFR1, FGFR2, FGFR3
15embryonic hindlimb morphogenesisGO:003511610.2FGF8, MSX2, TWIST1
16bone developmentGO:006034810.2FGF8, FGFR2, TWIST1
17embryonic forelimb morphogenesisGO:003511510.1ALX4, MSX2, TWIST1
18bone morphogenesisGO:006034910.1FGFR2, FGFR3, MSX2
19branching involved in salivary gland morphogenesisGO:006044510.0FGF8, FGFR1, FGFR2
20positive regulation of ERK1 and ERK2 cascadeGO:007037410.0FGF8, FGFR2, FGFR3
21neural plate morphogenesisGO:000183910.0FGF8, NOG
22orbitofrontal cortex developmentGO:002176910.0FGFR1, FGFR2
23positive regulation of epithelial cell proliferationGO:00506799.9FGFR2, NOG
24motor neuron axon guidanceGO:00080459.9FGF8, NOG
25regulation of phosphatidylinositol 3-kinase signalingGO:00140669.9FGF8, FGFR1, FGFR2, FGFR3
26phosphatidylinositol-mediated signalingGO:00480159.9FGF8, FGFR1, FGFR2, FGFR3
27odontogenesisGO:00424769.9FGF8, FGFR2, MSX2, TWIST1
28phosphatidylinositol-3-phosphate biosynthetic processGO:00360929.9FGF8, FGFR1, FGFR2, FGFR3
29epidermal growth factor receptor signaling pathwayGO:00071739.9FGF8, FGFR1, FGFR2, FGFR3
30embryonic cranial skeleton morphogenesisGO:00487019.9FGFR2, TGFBR1, TWIST1
31fibroblast growth factor receptor signaling pathwayGO:00085439.8FGF8, FGFR1, FGFR2, FGFR3
32embryonic limb morphogenesisGO:00303269.8FGFR1, MSX2, TWIST1
33embryonic digit morphogenesisGO:00427339.7MSX2, NOG, TWIST1
34bone mineralizationGO:00302829.7FGFR2, FGFR3, PHEX
35lung developmentGO:00303249.7FGF8, FGFR1, FGFR2
36Ras protein signal transductionGO:00072659.7FGF8, FGFR1, FGFR2, FGFR3
37MAPK cascadeGO:00001659.7FGF8, FGFR1, FGFR2, FGFR3
38vascular endothelial growth factor receptor signaling pathwayGO:00480109.6FGF8, FGFR1, FGFR2, FGFR3
39insulin receptor signaling pathwayGO:00082869.6FGF8, FGFR1, FGFR2, FGFR3
40BMP signaling pathwayGO:00305099.5FGF8, MSX2, NOG
41skeletal system morphogenesisGO:00487059.5ALX4, FGFR1, FGFR2, TGFBR1
42palate developmentGO:00600219.4ALX4, TGFBR1, TWIST1
43activation of MAPKK activityGO:00001869.3FGF8, FGFR1, FGFR2, TGFBR1
44epithelial to mesenchymal transitionGO:00018379.2FGFR2, NOG, TGFBR1
45skeletal system developmentGO:00015019.1FGFR1, NOG, TGFBR1
46osteoblast differentiationGO:00016499.1MSX2, NOG, TWIST1
47neurotrophin TRK receptor signaling pathwayGO:00480119.1FGF8, FGFR1, FGFR2, FGFR3
48in utero embryonic developmentGO:00017019.0FGFR2, NOG, TGFBR1, TWIST1
49negative regulation of transcription from RNA polymerase II promoterGO:00001228.9FGFR1, FGFR2, MSX2, NOG, TWIST1
50axon guidanceGO:00074118.5EFNB1, FGFR1, FGFR2, FGFR3, NOG

Molecular functions related to Craniosynostosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1fibroblast growth factor-activated receptor activityGO:000500710.5FGFR2, FGFR3
2protein tyrosine kinase activityGO:00047139.7FGFR1, FGFR2, FGFR3
3SMAD bindingGO:00463329.4TCF12, TGFBR1

Sources for Craniosynostosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
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38MGI
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47Novoseek
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50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet