MCID: CRS001
MIFTS: 42

Crescentic Glomerulonephritis malady

Category: Nephrological diseases

Aliases & Classifications for Crescentic Glomerulonephritis

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Aliases & Descriptions for Crescentic Glomerulonephritis:

Name: Crescentic Glomerulonephritis 11 13
 
Idiopathic Crescentic Glomerulonephritis 68

Classifications:



External Ids:

Disease Ontology11 DOID:13139
SNOMED-CT62 236398000, 45406000
NCIt45 C35444

Summaries for Crescentic Glomerulonephritis

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MalaCards based summary: Crescentic Glomerulonephritis, also known as idiopathic crescentic glomerulonephritis, is related to pauci-immune glomerulonephritis and gastric cancer. An important gene associated with Crescentic Glomerulonephritis is MPO (Myeloperoxidase), and among its related pathways are IL1 and megakaryocytes in obesity and Interleukin-10 signaling. Affiliated tissues include neutrophil, kidney and t cells, and related mouse phenotypes are neoplasm and immune system.

Related Diseases for Crescentic Glomerulonephritis

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Diseases related to Crescentic Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 137)
idRelated DiseaseScoreTop Affiliating Genes
1pauci-immune glomerulonephritis30.2NPHS2, PTPRO
2gastric cancer29.6NPHS2, PTPRO, SYNPO
3rapidly progressive glomerulonephritis11.5
4glomerulonephritis11.0
5vasculitis10.4
6endocarditis10.2
7cutaneous candidiasis10.2CCL2, ICAM1
8dancing eyes-dancing feet syndrome10.2CCL2, MPO
9arthritis10.2
10phlegmonous dacryocystitis10.2ICAM1, MPO, VCAM1
11dislocation of ear ossicle10.2ICAM1, MPO, VCAM1
12retinal ischemia10.2CCL2, CCR5, ICAM1
13rheumatoid arthritis10.1
14orofacial granulomatosis10.1CCR5, ICAM1, VCAM1
15epidermolysis bullosa simplex, sutosomal recessive 210.1CCL2, ICAM1, VCAM1
16hypopyon ulcer10.1ICAM1, VCAM1
17macrodactyly of the foot10.1ICAM1, VCAM1
18hemiplegia10.1CCL2, NPHS2, SYNPO
19subacute glomerulonephritis10.1ICAM1, MPO, TGFB1
20neuroaxonal dystrophy10.1CCL2, ICAM1, SERPINE1
21pauci-immune glomerulonephritis without anca10.1
22pauci-immune glomerulonephritis with anca10.1
23fasciitis10.1BPI, CTSG, MPO
24microcephaly, progressive, seizures, and cerebral and cerebellar atrophy10.1BPI, CTSG, MPO
25plantar fasciitis10.1CCL2, CCR5, VCAM1
26ependymoblastoma10.1CCR5, ICAM1, MPO, VCAM1
27bare lymphocyte syndrome, type i10.1CCL2, ICAM1, MPO, VCAM1
28uveitis10.1BPI, CCL2, ICAM1, MPO
29periosteal chondrosarcoma10.1ICAM1, SERPINE1, VCAM1
30perrault syndrome10.1ICAM1, SERPINE1, VCAM1
31membranous nephropathy10.1
32craniopharyngioma10.1ICAM1, SERPINE1, VCAM1
33sclerosing adenosis of breast10.1CCL2, ICAM1, TGFB1
34xerophthalmia10.1ICAM1, SERPINE1, VCAM1
35detrusor sphincter dyssynergia10.0CCL2, CCR5, TGFB1
36advanced sleep phase syndrome, familial, 110.0CCL2, CCR5, ICAM1, VCAM1
37citrullinemia, type ii, neonatal-onset10.0ICAM1, SERPINE1, VCAM1
38churg-strauss syndrome10.0
39endotheliitis10.0
40major depressive disorder and accelerated response to antidepressant drug treatment10.0BPI, CCR5, CTSG, MPO
41strawberry gallbladder10.0CCL2, ICAM1, MPO, TGFB1
42acute chest syndrome10.0CCL2, ICAM1, MPO, TGFB1
43pulmonary valve insufficiency10.0CCL2, SERPINE1, TGFB1
44cervix small cell carcinoma10.0ICAM1, SERPINE1, VCAM1
45biliary cirrhosis, primary, 210.0MPO, NPHS2, TGFB1
46aphthous stomatitis10.0NPHS2, TGFB1
47malignant hyperthermia susceptibility 110.0NPHS2, PTPRO, SYNPO
48lymphoma10.0
49amyloidosis10.0
50pigmentation disease10.0CCL2, ICAM1, TGFB1, VCAM1

Graphical network of the top 20 diseases related to Crescentic Glomerulonephritis:



Diseases related to crescentic glomerulonephritis

Symptoms & Phenotypes for Crescentic Glomerulonephritis

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MGI Mouse Phenotypes related to Crescentic Glomerulonephritis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.5CCR5, CTSG, ICAM1, SERPINE1, TGFB1
2MP:00053877.3CCL2, CCR5, CTSG, ICAM1, MPO, SERPINE1
3MP:00053857.0CCR5, ICAM1, MPO, NPHS2, PTPRO, SERPINE1

Drugs & Therapeutics for Crescentic Glomerulonephritis

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Drugs for Crescentic Glomerulonephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 35)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Cyclophosphamideapproved, investigationalPhase 2, Phase 3293550-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Anhydrous cyclophosphamide
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
 
DB00531
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
2
Methylprednisoloneapproved, vet_approvedPhase 2, Phase 3119383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
3
Prednisoneapproved, vet_approvedPhase 2, Phase 3139853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
4
Prednisoloneapproved, vet_approvedPhase 2, Phase 3119350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
5Immunosuppressive AgentsPhase 2, Phase 313086
6Immunoglobulin APhase 2, Phase 3120
7Protective AgentsPhase 2, Phase 37443
8Peripheral Nervous System AgentsPhase 2, Phase 323689
9AntiemeticsPhase 2, Phase 34022
10Autonomic AgentsPhase 2, Phase 310150
11Anti-Inflammatory AgentsPhase 2, Phase 310729
12Prednisolone phosphatePhase 2, Phase 31193
13Neuroprotective AgentsPhase 2, Phase 31716
14Prednisolone acetatePhase 2, Phase 31193
15Prednisolone hemisuccinatePhase 2, Phase 31193
16glucocorticoidsPhase 2, Phase 35103
17Gastrointestinal AgentsPhase 2, Phase 38402
18Methylprednisolone HemisuccinatePhase 2, Phase 31193
19Hormone AntagonistsPhase 2, Phase 313180
20HormonesPhase 2, Phase 314415
21Methylprednisolone acetatePhase 2, Phase 31193
22Antineoplastic Agents, HormonalPhase 2, Phase 35592
23Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 2, Phase 313168
24
Lisinoprilapproved, investigationalPhase 211783915-83-75362119
Synonyms:
(2S)-1-[(2S)-6-amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
(S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
(S)-1-(N(2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-L-proline
(S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
(S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
1-[Nalpha-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl]-L-proline
76547-98-3
77726-95-5
83915-83-7 (Parent)
AC1NSFPF
Acerbon
Acercomp
Alapril
BB_NC-1454
BIDD:GT0755
BPBio1_000290
BRD-K67966701-335-03-5
BRN 4276619
BSPBio_000262
C21H31N3O5
CCRIS 3568
CHEBI:43755
CHEMBL1237
CID5362119
Carace
Cipral
Cipril
Coric
D08131
DB00722
DivK1c_001037
Doneka
EINECS 278-488-1
HMS1921B14
HMS2090O14
HMS2092L21
HMS503O15
I06-1895
ICI-209K
IDI1_001037
Inhibril
Inopril
KBio1_001037
KBio2_000977
KBio2_003545
KBio2_006113
KBio3_002002
KBioGR_001599
KBioSS_000977
L0220
LPR
LS-118899
Linopril
Linvas
Lipril
Lisinal
 
Lisinopril
Lisinopril (INN)
Lisinopril (anhydrous)
Lisinopril Dihydrate
Lisinopril anhydrous
Lisinoprilum
Lisinoprilum [Latin]
Lisipril
Lisoril
Lispril
Longes
Loril
Lysinopril
MK 521
MK 522
MK-521
MLS001306436
MLS001306481
MolPort-002-507-428
N(2)-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
N-(1(S)-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
N2-((S)-1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
NCGC00179623-01
NINDS_001037
Noperten
Novatec
Presiten
Prestwick0_000301
Prestwick1_000301
Prestwick2_000301
Prestwick3_000301
Prinil
Prinivil
Prinzide
Renacor
SMR000544473
SPBio_001351
SPBio_002481
SPECTRUM1501217
Sinopril
Sinopryl
Spectrum2_001456
Spectrum3_000941
Spectrum4_001040
Spectrum5_000995
Spectrum_000497
TL8005499
Tensopril
Tensyn
Tersif
Vivatec
Zestoretic
Zestril
Zestril (TN)
[N2-[(S)-1-CARBOXY-3-PHENYLPROPYL]-L-LYSYL-L-PROLINE
[N2-[(S)-1-CARBOXY-3-phenylpropyl]-L-lysyl-L-proline
lisinopril
25
protease inhibitorsPhase 25471
Synonyms:
 
protease inhibitors
26Antihypertensive AgentsPhase 24207
27HIV Protease InhibitorsPhase 25470
28Angiotensin-Converting Enzyme InhibitorsPhase 2724
29
Mycophenolate mofetilapproved, investigational952128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
30
Mycophenolic acidapproved95224280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
31Antirheumatic Agents10956
32Antibiotics, Antitubercular7180
33Alkylating Agents4827
34Anti-Bacterial Agents11226
35Antineoplastic Agents, Alkylating4603

Interventional clinical trials:

idNameStatusNCT IDPhase
1Immunoadsorption in Anti-GBM Glomerulonephritis.Not yet recruitingNCT02765789Phase 4
2Trial of Plasma Exchange for Severe Crescentic IgA NephropathyEnrolling by invitationNCT02647255Phase 2, Phase 3
3ACE-inhibitors in Extracapillary GlomerulonephritisRecruitingNCT02682459Phase 2
4Mycophenolate Mofetil Versus Intravenous Cyclophosphamide Pulses in the Treatment of Crescentic IgA NephropathyCompletedNCT00301600

Search NIH Clinical Center for Crescentic Glomerulonephritis

Genetic Tests for Crescentic Glomerulonephritis

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Anatomical Context for Crescentic Glomerulonephritis

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MalaCards organs/tissues related to Crescentic Glomerulonephritis:

36
Neutrophil, Kidney, T cells, Bone, Endothelial, Monocytes, Bone marrow

Publications for Crescentic Glomerulonephritis

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Articles related to Crescentic Glomerulonephritis:

(show top 50)    (show all 558)
idTitleAuthorsYear
1
A rare case of concurrent myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-associated necrotising and crescentic glomerulonephritis and membranous glomerulonephritis. (27931720)
2017
2
Formation of tight junctions between neighboring podocytes is an early ultrastructural feature in experimental crescentic glomerulonephritis. (27920570)
2016
3
Granulomatosis with Polyangiitis Presenting as Pauci-Immune Crescentic Glomerulonephritis in Pregnancy. (27293925)
2016
4
Microscopic polyangiitis with crescentic glomerulonephritis initially presenting as acute pancreatitis. (26864299)
2016
5
Crescentic glomerulonephritis in children: a single centre experience. (26684304)
2016
6
Pauci-Immune Crescentic Glomerulonephritis in Connective Tissue Disease. (27504208)
2016
7
Anti-glomerular basement membrane crescentic glomerulonephritis: A report from India and review of literature. (27795626)
2016
8
Pauci-immune crescentic glomerulonephritis without ANCA in a patient presenting with Candida parapsilosis endocarditis. (26897307)
2016
9
AJKD Atlas of Renal Pathology: Pauci-immune Necrotizing Crescentic Glomerulonephritis. (27772637)
2016
10
Pauci Immune crescentic glomerulonephritis in a patient with T-cell lymphoma and argyria. (27189346)
2016
11
Anti-CD20 therapy and pauci-immune crescentic glomerulonephritis. (26786252)
2016
12
Hilar and para-aortic necrotizing lymphadenopathy associated with antineutrophil cytoplasmic antibody-negative pauci-immune crescentic glomerulonephritis. (27424701)
2016
13
Dual anti-neutrophil cytoplasmic antibody-related pauci-immune crescentic glomerulonephritis in a patient with SjAPgren's syndrome. (27384449)
2016
14
Clinical spectrum and outcomes of crescentic glomerulonephritis: A single center experience. (27512296)
2016
15
Poor renal outcomes in patients with anti-neutrophil cytoplasmic antibody-associated crescentic glomerulonephritis and normal renal function at diagnosis. (26742758)
2016
16
Murine Double Minute-2 Inhibition Ameliorates Established Crescentic Glomerulonephritis. (27102769)
2016
17
Crescentic Glomerulonephritis: Variation in Markers of Kidney Function and Structure. (26916371)
2016
18
Necrotizing and crescentic glomerulonephritis with membranous nephropathy in a patient exposed to levamisole-adulterated cocaine. (26985374)
2016
19
Crescentic Glomerulonephritis Associated with Pulmonary Tuberculosis. (26894074)
2016
20
Coexistence of Acute Crescent Glomerulonephritis and IgG4-Related Kidney Disease. (27504450)
2016
21
Glomerular Capillary and Endothelial Cell Injury is Associated with the Formation of Necrotizing and Crescentic Lesions in Crescentic Glomerulonephritis. (25797872)
2015
22
A Case of Membranous Glomerulonephritis with Superimposed Anti-Neutrophil Cytoplasmic Antibody-Associated Rapidly Progressive Crescentic Glomerulonephritis. (26306306)
2015
23
ANCA-Negative Pauci-Immune Crescentic Glomerulonephritis Linked with Non-Small Cell Carcinoma of the Lung. (26266249)
2015
24
Re: prognostic factors in crescentic glomerulonephritis: a single-center experience. (26174464)
2015
25
A rare case of type-I auto-immune hepatitis and thyroiditis presenting with crescentic glomerulonephritis. (26354574)
2015
26
Interleukin 17 signaling drives Type I Interferon induced proliferative crescentic glomerulonephritis in lupus-prone mice. (26556529)
2015
27
Crescentic glomerulonephritis and membranous nephropathy: a rare coexistence. (26092054)
2015
28
Green tea polyphenol (-)-epigallocatechin-3-gallate restores nrf2 activity and ameliorates crescentic glomerulonephritis. (25785827)
2015
29
Necrotizing crescentic glomerulonephritis related to sarcoidosis: a case report. (26651490)
2015
30
ANCA-negative crescentic glomerulonephritis closely following two episodes of sepsis. (25735581)
2015
31
Crescentic glomerulonephritis: data from the spanish glomerulonephritis registry. (25684569)
2015
32
Bartonella henselae infection-associated vasculitis and crescentic glomerulonephritis leading to renal allograft loss. (25753276)
2015
33
ANCA positive crescentic glomerulonephritis outcome in a Central East European cohort: a retrospective study. (26123651)
2015
34
Etiology and Outcome of Crescentic Glomerulonephritis FromA aA Single Center in China: A 10-Year Review. (26388283)
2015
35
Pauci-Immune Crescentic Glomerulonephritis: An ANCA-Associated Vasculitis. (26688808)
2015
36
ANCA-positive crescentic glomerulonephritis in a patient with rheumatoid arthritis treated with anti-tumor necrosis factor alpha. (26012729)
2015
37
Hemorrhagic complications associated with PR3-ANCA crescentic glomerulonephritis. (25697228)
2015
38
Antineutrophil Cytoplasmic Antibodies-Negative Pauci-Immune Crescentic Glomerulonephritis Associated with Multiple Myeloma. (26120578)
2015
39
Urinary thrombin: a novel marker of glomerular inflammation for the diagnosis of crescentic glomerulonephritis (prospective observational study). (25742509)
2015
40
Prognostic factors in crescentic glomerulonephritis: a single-center experience. (25599734)
2015
41
Infective endocarditis-induced crescentic glomerulonephritis dramatically improved after removal of vegetations and valve replacement. (25635440)
2015
42
Pauci-Immune Necrotizing and Crescentic Glomerulonephritis with Membranous Lupus Nephritis, Fifteen Years after Initial Diagnosis of Secondary Membranous Nephropathy. (26558120)
2015
43
C1q nephropathy and isolated CD59 deficiency manifesting as necrotizing crescentic glomerulonephritis: A rare association of two diseases. (26586072)
2015
44
Expression of Ser729 phosphorylated PKCepsilon in experimental crescentic glomerulonephritis: an immunohistochemical study. (24998921)
2014
45
Rapidly progressive crescentic glomerulonephritis: Early treatment is a must. (24657897)
2014
46
IgM nephropathy presenting as full blown crescentic glomerulonephritis: first report in the literature. (24849066)
2014
47
Crescentic glomerulonephritis in a child with Heiner syndrome. (26388600)
2014
48
New-onset bone marrow aplasia in a 15-year-old adolescent with pauci-immune crescentic glomerulonephritis: Questions. (24981196)
2014
49
Susceptibility quantitative trait loci for pathogenic leucocytosis in SCG/Kj mice, a spontaneously occurring crescentic glomerulonephritis and vasculitis model. (24654803)
2014
50
Crescentic glomerulonephritis in non-asthmatic Churg-Strauss syndrome. (24626013)
2014

Variations for Crescentic Glomerulonephritis

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Expression for genes affiliated with Crescentic Glomerulonephritis

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Search GEO for disease gene expression data for Crescentic Glomerulonephritis.

Pathways for genes affiliated with Crescentic Glomerulonephritis

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Pathways related to Crescentic Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 18)
idSuper pathwaysScoreTop Affiliating Genes
19.9CCL2, ICAM1
29.5CCL2, CCR5, ICAM1
3
Show member pathways
9.5CCL2, ICAM1, SERPINE1
49.4TGFB1, VCAM1
59.4CCL2, ICAM1, VCAM1
69.4CCL2, ICAM1, VCAM1
79.4CCL2, ICAM1, TGFB1
89.4CCL2, ICAM1, TGFB1
99.2ICAM1, SERPINE1, VCAM1
10
Show member pathways
9.2CCL2, ICAM1, MPO, SERPINE1
119.1CCL2, ICAM1, MPO, VCAM1
129.1ICAM1, TGFB1, VCAM1
138.9CCL2, ICAM1, TGFB1, VCAM1
148.9CCL2, ICAM1, TGFB1, VCAM1
158.6NPHS2, PTPRO, SYNPO, TGFB1
168.4CCL2, ICAM1, SERPINE1, TGFB1, VCAM1
17
Show member pathways
8.3CTSG, ICAM1, SERPINE1, TGFB1, VCAM1
18
Show member pathways
8.0CCL2, CCR5, ICAM1, SERPINE1, TGFB1, VCAM1

GO Terms for genes affiliated with Crescentic Glomerulonephritis

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Cellular components related to Crescentic Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1azurophil granule lumenGO:003557810.4BPI, CTSG, MPO
2secretory granuleGO:00301419.4CTSG, MPO, TGFB1
3cell surfaceGO:00099868.4CCR5, CTSG, ICAM1, TFPI, TGFB1, VCAM1
4extracellular regionGO:00055768.3BPI, CCL2, CTSG, MPO, SERPINE1, TFPI
5extracellular exosomeGO:00700628.1BPI, CTSG, ICAM1, MPO, NPHS2, PTPRO
6extracellular spaceGO:00056157.5BPI, CCL2, CTSG, ICAM1, MPO, SERPINE1
7plasma membraneGO:00058866.3CCR5, CTSG, ICAM1, NPHS2, PTPRO, SERPINE1

Biological processes related to Crescentic Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 22)
idNameGO IDScoreTop Affiliating Genes
1cellular response to interleukin-6GO:007135410.6CCL2, ICAM1
2defense response to fungusGO:005083210.6CTSG, MPO
3positive regulation of cellular extravasationGO:000269310.6CCL2, ICAM1
4negative regulation of growth of symbiont in hostGO:004413010.6CTSG, MPO
5chronic inflammatory responseGO:000254410.4CCL2, VCAM1
6positive regulation of monocyte chemotaxisGO:009002610.4CCL2, SERPINE1
7negative regulation of endothelial cell apoptotic processGO:200035210.4ICAM1, SERPINE1
8positive regulation of collagen biosynthetic processGO:003296710.4CCL2, TGFB1
9leukocyte cell-cell adhesionGO:000715910.3ICAM1, VCAM1
10membrane to membrane dockingGO:002261410.3ICAM1, VCAM1
11response to cholesterolGO:007072310.2CCR5, TGFB1
12cellular response to dexamethasone stimulusGO:007154910.1CCL2, ICAM1, TGFB1
13defense response to Gram-negative bacteriumGO:005082910.1BPI, CTSG, SERPINE1
14cellular response to tumor necrosis factorGO:007135610.1CCL2, ICAM1, VCAM1
15positive regulation of ERK1 and ERK2 cascadeGO:007037410.0CCL2, ICAM1, TGFB1
16response to ethanolGO:004547110.0CCL2, ICAM1, VCAM1
17immune responseGO:00069559.9BPI, CCL2, CCR5, CTSG
18cellular response to interleukin-1GO:00713479.8CCL2, ICAM1, TFPI
19agingGO:00075689.6CCL2, MPO, TGFB1, VCAM1
20response to hypoxiaGO:00016669.4CCL2, ICAM1, TGFB1, VCAM1
21cellular response to lipopolysaccharideGO:00712228.6CCL2, CCR5, CTSG, ICAM1, SERPINE1, TFPI
22response to lipopolysaccharideGO:00324968.0CCL2, CTSG, ICAM1, MPO, TFPI, VCAM1

Molecular functions related to Crescentic Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1heparin bindingGO:00082019.6CCL2, CTSG, MPO

Sources for Crescentic Glomerulonephritis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet