MCID: CRS001
MIFTS: 44

Crescentic Glomerulonephritis malady

Nephrological diseases category
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Summaries for Crescentic Glomerulonephritis

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Wikipedia:65 Rapidly progressive glomerulonephritis (RPGN) is a syndrome of the kidney that is characterized by a... more...

MalaCards based summary: Crescentic Glomerulonephritis, also known as idiopathic crescentic glomerulonephritis, is related to glomerulonephritis and nephritis. An important gene associated with Crescentic Glomerulonephritis is TNFRSF6B (tumor necrosis factor receptor superfamily, member 6b, decoy). The compounds chloramphenicol and heparin have been mentioned in the context of this disorder. Affiliated tissues include kidney, neutrophil and bone, and related mouse phenotype immune system.

Aliases & Classifications for Crescentic Glomerulonephritis

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Crescentic Glomerulonephritis, Aliases & Descriptions:

Name: Crescentic Glomerulonephritis 8 10
 
Idiopathic Crescentic Glomerulonephritis 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


External Ids:

Disease Ontology8 DOID:13139
SNOMED-CT57 236398000, 45406000
NCIt39 C35444

Related Diseases for Crescentic Glomerulonephritis

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Graphical network of the top 20 diseases related to Crescentic Glomerulonephritis:



Diseases related to crescentic glomerulonephritis

Symptoms for Crescentic Glomerulonephritis

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Drugs & Therapeutics for Crescentic Glomerulonephritis

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Drug clinical trials:

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Search NIH Clinical Center for Crescentic Glomerulonephritis

Genetic Tests for Crescentic Glomerulonephritis

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Anatomical Context for Crescentic Glomerulonephritis

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MalaCards organs/tissues related to Crescentic Glomerulonephritis:

32
Kidney, Neutrophil, Bone, T cells, Monocytes, Bone marrow, Endothelial, Liver, Thyroid, Testes, Lymph node, Lung, Breast, Skin, Myeloid

Animal Models for Crescentic Glomerulonephritis or affiliated genes

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MGI Mouse Phenotypes related to Crescentic Glomerulonephritis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.6CMA1, MPO, SCGB1A1, TFPI, DARC

Publications for Crescentic Glomerulonephritis

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Articles related to Crescentic Glomerulonephritis:

(show top 50)    (show all 507)
idTitleAuthorsYear
1
Clinicopathologic spectrum of crescentic glomerulonephritis: a hospital-based study. (24821180)
2014
2
Necrotizing crescentic glomerulonephritis in a patient with positive serologies for lupus and antineutrophil cytoplasmic antibodies. (25259824)
2014
3
ANCA-mediated crescentic glomerulonephritis with linear deposition of IgG along the glomerular basement membrane. (24821165)
2014
4
Update on crescentic glomerulonephritis. (24948005)
2014
5
Management of crescentic glomerulonephritis: what are the recent advances? (23689584)
2013
6
Myeloperoxidase-antineutrophil cytoplasmic antibody-associated crescentic glomerulonephritis in autosomal dominant polycystic kidney disease. (23617397)
2013
7
Characteristics and outcome of crescentic glomerulonephritis in patients with both antineutrophil cytoplasmic antibody and anti-glomerular basement membrane antibody. (23624587)
2013
8
Mice with defective Fas ligand are protected from crescentic glomerulonephritis. (21918502)
2012
9
Atorvastatin enhances humoral immune responses but does not alter renal injury in experimental crescentic glomerulonephritis. (19796023)
2009
10
Anti-VEGF therapy for crescentic glomerulonephritis? (18371550)
2008
11
Clinical spectrum and outcome of crescentic glomerulonephritis in children in developing countries. (18071760)
2008
12
Periglomerular accumulation of dendritic cells in rat crescentic glomerulonephritis. (17557270)
2007
13
Antineutrophil cytoplasmic autoantibody-negative Pauci-immune crescentic glomerulonephritis. (17215440)
2007
14
T cells in crescentic glomerulonephritis. (16624930)
2006
15
Crescentic glomerulonephritis in a child with infective endocarditis. (16703379)
2006
16
A rare form of crescentic glomerulonephritis with mixed immunopathological features. (15841695)
2004
17
Thrombotic thrombocytopenic purpura complicating SjAPgren's syndrome with crescentic glomerulonephritis and membranous nephritis. (17143670)
2004
18
In situ expression of connective tissue growth factor in human crescentic glomerulonephritis. (14758550)
2004
19
Rapidly progressive crescentic glomerulonephritis. (12631105)
2003
20
Pauci-immune crescentic glomerulonephritis. (15025274)
2003
21
Activation and cellular localization of the p38 and JNK MAPK pathways in rat crescentic glomerulonephritis. (14633134)
2003
22
Gastric cancer diagnosed in a patient with crescentic glomerulonephritis. (14716523)
2003
23
p38 MAPK phosphorylation and NF-kappa B activation in human crescentic glomerulonephritis. (12032188)
2002
24
Preventive effect of sulphated colominic acid on P-selectin-dependent infiltration of macrophages in experimentally induced crescentic glomerulonephritis. (12100021)
2002
25
Up-regulation of extracellular matrix proteoglycans and collagen type I in human crescentic glomerulonephritis. (11168935)
2001
26
Coexistence of Fabry's disease and necrotizing and crescentic glomerulonephritis. (11200872)
2001
27
Early renal allograft loss in a patient with crescentic glomerulonephritis in the native kidney. (11136188)
2001
28
Macrophage-derived MT1-MMP and increased MMP-2 activity are associated with glomerular damage in crescentic glomerulonephritis. (10878552)
2000
29
B7.1 and B7.2 co-stimulatory molecules regulate crescentic glomerulonephritis. (10820386)
2000
30
Crescentic glomerulonephritis--a manifestation of a nephritogenic Th1 response? (10963141)
2000
31
Tissue factor, plasminogen activator inhibitor-1, and thrombin receptor expression in human crescentic glomerulonephritis. (10739796)
2000
32
Immunopathogenesis of crescentic glomerulonephritis. (10456257)
1999
33
Necrotizing-crescentic glomerulonephritis in ANCA-associated vasculitis: the role of monocytes. (10435868)
1999
34
Therapeutic effect of glucocorticoid on experimental crescentic glomerulonephritis. (10521089)
1999
35
Expression of lymphotactin mRNA in experimental crescentic glomerulonephritis. (9717977)
1998
36
Cytomegalovirus-induced necrotizing and crescentic glomerulonephritis in a renal transplant patient. (9820453)
1998
37
Quantification of changes in transforming growth factor-beta1 gene expression in experimental crescentic glomerulonephritis. (9034137)
1997
38
Tissue factor in crescentic glomerulonephritis. (9060816)
1997
39
Crucial role of CD8-positive lymphocytes in glomerular expression of ICAM-1 and cytokines in crescentic glomerulonephritis of WKY rats. (9144517)
1997
40
Membranous lupus nephritis with antineutrophil cytoplasmic antibody-associated segmental necrotizing and crescentic glomerulonephritis. (9002540)
1997
41
Modulators of crescentic glomerulonephritis. (8959617)
1996
42
Long-term clinical course in acute crescentic glomerulonephritis. (8899486)
1996
43
Antineutrophil cytoplasmic autoantibody-positive crescentic glomerulonephritis associated with thiamazole therapy. (8956314)
1996
44
Renal expression of tissue factor pathway inhibitor and evidence for a role in crescentic glomerulonephritis in rabbits. (8755641)
1996
45
Myeloperoxidase-antineutrophil cytoplasmic antibody-positive crescentic glomerulonephritis complicating the course of Graves' disease: report of three adult cases. (7485130)
1995
46
Is the association between crescentic glomerulonephritis and renal cell carcinoma coincidental? (8302427)
1993
47
Methylprednisolone and cyclophosphamide pulse therapy in crescentic glomerulonephritis: safety and effectiveness. (8210561)
1993
48
Crescentic glomerulonephritis related to hepatitis B virus. (1495931)
1992
49
Crescentic glomerulonephritis in children: a review of 43 cases. (1415376)
1992
50
Correlation between T cells and experimental crescentic glomerulonephritis. (2125253)
1990

Variations for Crescentic Glomerulonephritis

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Expression for genes affiliated with Crescentic Glomerulonephritis

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Expression patterns in normal tissues for genes affiliated with Crescentic Glomerulonephritis

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Pathways for genes affiliated with Crescentic Glomerulonephritis

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Compounds for genes affiliated with Crescentic Glomerulonephritis

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Sources:
44Novoseek, 2BitterDB, 50PharmGKB, 11DrugBank, 28IUPHAR, 24HMDB
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Compounds related to Crescentic Glomerulonephritis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1chloramphenicol44 2 50 1112.2MPO, SCGB1A1
2heparin44 28 24 1112.1CMA1, MPO, TFPI
3creatinine448.7SYNPO, MPO, SCGB1A1
4alanine448.4DARC, TFPI, SCGB1A1
5calcium44 50 24 1111.0CMA1, MPO, SCGB1A1, TFPI

GO Terms for genes affiliated with Crescentic Glomerulonephritis

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Cellular components related to Crescentic Glomerulonephritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:0301418.5CMA1, MPO, SCGB1A1
2extracellular spaceGO:0056158.3MPO, SCGB1A1, TNFRSF6B, TFPI

Biological processes related to Crescentic Glomerulonephritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to lipopolysaccharideGO:0324969.2MPO, SCGB1A1
2regulation of inflammatory responseGO:0507279.1CMA1, SCGB1A1
3defense responseGO:0069529.1MPO, DARC

Molecular functions related to Crescentic Glomerulonephritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1receptor activityGO:0048729.5TNFRSF6B, DARC

Products for genes affiliated with Crescentic Glomerulonephritis

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  • Antibodies
  • Proteins
  • Lysates

Sources for Crescentic Glomerulonephritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet