MCID: CRB006
MIFTS: 27

Cribriform Carcinoma malady

Cancer category

Summaries for Cribriform Carcinoma

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33MalaCards
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MalaCards: Cribriform Carcinoma, also known as ductal carcinoma, cribriform type, is related to papillary carcinoma and bone carcinoma. An important gene associated with Cribriform Carcinoma is IRS4 (insulin receptor substrate 4). The compounds progestins and dihydrotestosterone have been mentioned in the context of this disorder. Affiliated tissues include lymph node, colon and pancreas.

Aliases & Classifications for Cribriform Carcinoma

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 57SNOMED-CT, 35MeSH, 40NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer


Aliases & Descriptions:

cribriform carcinoma 8 10
ductal carcinoma, cribriform type 8
carcinoma, cribriform 61
carcinoma cribriform 45


External Ids:

Disease Ontology8 DOID:5675
MeSH35 D000230
SNOMED-CT57 30156004
NCIt40 C3680

Related Diseases for Cribriform Carcinoma

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Cribriform Carcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1papillary carcinoma10.3
2bone carcinoma10.1
3adenoid cystic carcinoma10.1
4breast malignant phyllodes tumor10.1
5thyroid carcinoma, papillary, somatic10.1
6phyllode tumor10.1
7ductal carcinoma in situ10.0PGR
8li-fraumeni syndrome10.0PIP, PGR
9ovarian cancer10.0PGR, PIP
10breast cancer10.0PGR, PIP

Graphical network of diseases related to Cribriform Carcinoma:



Diseases related to cribriform carcinoma

Clinical Features for Cribriform Carcinoma

Drugs & Therapeutics for Cribriform Carcinoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Cribriform Carcinoma

Drug clinical trials:

Search ClinicalTrials for Cribriform Carcinoma

Search NIH Clinical Center for Cribriform Carcinoma

Search CenterWatch for Cribriform Carcinoma

Genetic Tests for Cribriform Carcinoma

Anatomical Context for Cribriform Carcinoma

Sources:
33MalaCards
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MalaCards organs/tissues related to Cribriform Carcinoma:

33
Lymph node, Colon, Pancreas, Thyroid, Salivary gland, Breast, Prostate

Animal Models for Cribriform Carcinoma or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Cribriform Carcinoma

Sources:
51PubMed
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Articles related to Cribriform Carcinoma:

(show all 49)
idTitleAuthorsYear
1
Invasive cribriform carcinoma in a Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified. (23412348)
2013
2
Cribriform morular variant of papillary thyroid carcinoma: clinical and cytomorphological features on fine-needle aspiration. (23406819)
2013
3
Cribriform Morular Variant of Papillary Thyroid Carcinoma in a Patient with an Incidental Neck Lump: a Case Report and Review of the Literature. (24190100)
2013
4
Cribriform-morular variant of papillary thyroid carcinoma displaying poorly differentiated features. (23349472)
2013
5
Cribriform-morular variant of papillary thyroid carcinoma: ultrasonographic and clinical characteristics. (22892017)
2013
6
Cribriform-morular variant of papillary thyroid carcinoma in an 8-year-old girl: a case report with immunohistochemical and molecular testing. (22494995)
2012
7
Familial adenomatous polyposis-associated papillary thyroid carcinoma shows an indolent course and usually, but not always, belongs to the cribriform-morular variant of papillary thyroid carcinoma. (22236755)
2012
8
Invasive cribriform carcinoma arising in malignant phyllodes tumor of breast: a case report. (23110003)
2012
9
Automated reconstruction algorithm for identification of 3D architectures of cribriform ductal carcinoma in situ. (22970156)
2012
10
Cribriform-Morular Variant of Papillary Thyroid Carcinoma: US and Clinical Characteristics. (22642507)
2012
11
Cribriform-morular variant of papillary thyroid carcinoma: characteristic histologic feature of adenomatous polyposis. A case report. (22387099)
2012
12
Primary cutaneous cribriform carcinoma of the neck: a case report. (23316623)
2012
13
A pure invasive cribriform carcinoma of the breast with bone metastasis if untreated for thirteen years: a case report and literature review. (23167837)
2012
14
Cutaneous cribriform carcinoma: a short comment. (21315957)
2011
15
Sonographic findings of invasive cribriform carcinoma of the breast. (21527619)
2011
16
Intraductal carcinoma of salivary gland (so-called low-grade cribriform cystadenocarcinoma) arising in an intraparotid lymph node. (21442195)
2011
17
Low-grade cribriform cystadenocarcinoma of the parotid gland: a neoplasm with favorable prognosis, distinct from salivary duct carcinoma. (21068068)
2010
18
Primary cutaneous cribriform apocrine carcinoma: a clinicopathologic and immunohistochemical study of 26 cases of an under-recognized cutaneous adnexal neoplasm. (19751882)
2009
19
The cytological, clinical, and pathological features of the cribriform-morular variant of papillary thyroid carcinoma and mutation analysis of CTNNB1 and BRAF genes. (19534622)
2009
20
The T1799A BRAF mutation is absent in cribriform-morular variant of papillary carcinoma. (19415957)
2009
21
Cribriform-morular variant of papillary thyroid carcinoma: molecular characterization of a case with neuroendocrine differentiation and aggressive behavior. (19095577)
2009
22
Grading of invasive cribriform carcinoma on prostate needle biopsy: an interobserver study among experts in genitourinary pathology. (18724248)
2008
23
Cribriform carcinoma of the gallbladder: a clinicopathologic study of 7 cases. (18769339)
2008
24
Invasive cribriform breast carcinomas in patients with grade 1 and stage IIA (T2 N0 M0) breast cancer strongly express the v3 and v6, but not the v4 isoforms of the metastatic marker CD44. (18348657)
2008
25
Immunohistochemical phenotype of cutaneous cribriform carcinoma with a panel of 15 antibodies. (18085381)
2007
26
Report on a case of pure cribriform carcinoma of the breast with internal mammary node metastasis: description of the case and review of the literature. (16869243)
2006
27
Mutational analysis of the APC gene in cribriform-morula variant of papillary thyroid carcinoma. (16680592)
2006
28
Cytologic features of cribriform-morular variant of papillary carcinoma of the thyroid: a case report. (15717760)
2005
29
Invasive cribriform carcinoma with extensive microcalcifications in the male breast. (15858447)
2005
30
Primary cutaneous cribriform carcinoma: a rare apocrine tumour. (16115058)
2005
31
Cribriform-morular variant of papillary thyroid carcinoma: ultrastructural study and somatic/germline mutation analysis of the APC gene. (15205109)
2004
32
Cribriform-morular variant of papillary thyroid carcinoma: clue to early detection of familial adenomatous polyposis-associated colon cancer. (15593462)
2004
33
Morules in cribriform-morular variant of papillary thyroid carcinoma: Immunohistochemical characteristics and distinction from squamous metaplasia. (15233643)
2004
34
Cribriform-Morular Variant of Papillary Carcinoma: Association with Familial Adenomatous Polyposis - Report of Three Cases and Review of Literature. (15912189)
2004
35
Cribriform-morular variant of papillary thyroid carcinoma: a pathological and molecular genetic study with evidence of frequent somatic mutations in exon 3 of the beta-catenin gene. (12474227)
2003
36
Somatic but not germline mutation of the APC gene in a case of cribriform-morular variant of papillary thyroid carcinoma. (11293895)
2001
37
A case report of cribriform carcinoma of the pancreas with long time survival. (11268983)
2001
38
The cribriform features of adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma: cytokeratin and integrin expression. (11745070)
2001
39
Fine needle aspiration cytology of invasive cribriform carcinoma of the breast with osteoclastlike giant cells: a case report. (11480724)
2001
40
Cribriform-morular variant of papillary carcinoma: a distinctive variant representing the sporadic counterpart of familial adenomatous polyposis-associated thyroid carcinoma? (10229505)
1999
41
Cribriform carcinoma of the prostate and cribriform prostatic intraepithelial neoplasia: incidence and clinical implications. (9669346)
1998
42
Detection of chromosomal anomalies and c-myc gene amplification in the cribriform pattern of prostatic intraepithelial neoplasia and carcinoma by fluorescence in situ hybridization. (9388062)
1997
43
Infiltrating cribriform carcinoma of the breast. A clinico-pathologic and immunohistochemical study of 5 cases. (8780923)
1996
44
Involvement of collagenous spherulosis by lobular carcinoma in situ. Potential confusion with cribriform ductal carcinoma in situ. (7503359)
1995
45
The radiological appearances of invasive cribriform carcinoma of the breast. Nottingham Breast Team. (7955831)
1994
46
Fine needle aspiration of invasive cribriform carcinoma with benign osteoclast-like giant cells of histiocytic origin. A case report. (8191846)
1994
47
Light and electron microscopic study of an invasive cribriform carcinoma with extensive microcalcification developing in a breast with silicone augmentation. (7810003)
1994
48
Infiltrating cribriform carcinoma of the breast: a distinctive clinicopathologic entity. (2312110)
1990
49
Invasive cribriform carcinoma of the breast. (6884999)
1983

Genetic Variations for Cribriform Carcinoma

Expression for genes affiliated with Cribriform Carcinoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cribriform Carcinoma

Search GEO for disease gene expression data for Cribriform Carcinoma.

Pathways for genes affiliated with Cribriform Carcinoma

Compounds for genes affiliated with Cribriform Carcinoma

Sources:
45Novoseek, 29IUPHAR, 11DrugBank, 24HMDB, 50PharmGKB
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Compounds related to Cribriform Carcinoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1progestins459.2PGR, PIP
2dihydrotestosterone45 29 11 2412.1PGR, PIP
3paraffin459.1PGR, PIP
4tamoxifen45 50 29 1112.0PIP, PGR
5estradiol45 11 2410.8PGR, PIP

GO Terms for genes affiliated with Cribriform Carcinoma

Products for genes affiliated with Cribriform Carcinoma

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Sources for Cribriform Carcinoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet