MCID: CRB006
MIFTS: 43

Cribriform Carcinoma

Categories: Cancer diseases

Aliases & Classifications for Cribriform Carcinoma

MalaCards integrated aliases for Cribriform Carcinoma:

Name: Cribriform Carcinoma 12 14
Ductal Carcinoma, Cribriform Type 12
Carcinoma, Cribriform 69
Carcinoma Cribriform 52

Classifications:



External Ids:

Disease Ontology 12 DOID:5675
MeSH 42 D000230
NCIt 47 C3680
SNOMED-CT 64 30156004
UMLS 69 C0205643

Summaries for Cribriform Carcinoma

MalaCards based summary : Cribriform Carcinoma, also known as ductal carcinoma, cribriform type, is related to bartholin's gland benign neoplasm and gallbladder leiomyoma. An important gene associated with Cribriform Carcinoma is PGR (Progesterone Receptor), and among its related pathways/superpathways are Developmental Biology and AMP-activated Protein Kinase (AMPK) Signaling. The drugs Fentanyl and Cevimeline have been mentioned in the context of this disorder. Affiliated tissues include salivary gland, breast and lung, and related phenotypes are Increased cell death HMECs cells and cardiovascular system

Related Diseases for Cribriform Carcinoma

Diseases related to Cribriform Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 227)
id Related Disease Score Top Affiliating Genes
1 bartholin's gland benign neoplasm 11.0 ESR1 PGR
2 gallbladder leiomyoma 10.9 ESR1 PGR
3 gastritis 10.9 ERBB2 PGR
4 salivary gland adenoid cystic carcinoma 10.9
5 fallopian tube benign neoplasm 10.9 ESR1 PGR
6 paranasal sinus disease 10.9 ESR1 PGR
7 dartoic leiomyoma 10.9 ESR1 PGR
8 bile duct rhabdomyosarcoma 10.9 KIT KLK3
9 blastema predominant kidney wilms' tumor 10.8 PGR TP53
10 pseudounicornuate uterus 10.8 KIT PGR TP63
11 rectal neoplasm 10.8 ESR1 KIT PGR
12 large cell acanthoma 10.8 ESR1 KIT PGR
13 urinary bladder inverted papilloma 10.8 ESR1 PGR
14 glaucoma, hereditary 10.8 ERBB2 ESR1 PGR
15 tetrahydrobiopterin-responsive hyperphenylalaninemia/phenylketonuria 10.8 ESR1 KIT PGR
16 adult spinal cord glioblastoma multiforme 10.8 ERBB2 KRT8
17 fallopian tube clear cell adenocarcinoma 10.8 ESR1 TP53
18 spinal cancer 10.8 ERBB2 ESR1 PGR
19 subglottis verrucous carcinoma 10.8 ERBB2 ESR1 PGR
20 her2-receptor positive breast cancer 10.8 ERBB2 ESR1 PGR
21 gangliosidosis gm2 10.8 ESR1 KIT PGR
22 skin sarcoma 10.8 ERBB2 PGR
23 malignant thyroid stimulating hormone producing neoplasm of pituitary gland 10.8 ERBB2 ESR1 PGR
24 esophagus sarcoma 10.8 ESR1 KLK3 PGR
25 cell type benign neoplasm 10.7 ERBB2 ESR1 PGR
26 mucinous adenocarcinoma 10.7 KIT KLK3 KRT20
27 bladder tuberculosis 10.7 ERBB2 KRT5
28 deafness, autosomal dominant 8/12 10.7 ESR1 PGR
29 ureter adenocarcinoma 10.7 ERBB2 ESR1 PGR
30 her2-receptor negative breast cancer 10.7 ERBB2 PGR
31 progesterone-receptor negative breast cancer 10.7 ERBB2 ESR1 PGR
32 capillary disease 10.7 ESR1 KLK3 PGR
33 struma ovarii 10.7 KLK3 KRT20 PGR
34 central nervous system organ benign neoplasm 10.7 ESR1 PGR TP53
35 penis squamous cell carcinoma 10.7 ERBB2 KRT5 PGR
36 lung adenoma 10.7 ESR1 PGR TP53
37 nerve fibre bundle defect 10.7 ERBB2 ESR1
38 linitis plastica 10.7 KRT5 PGR TP63
39 intestinal perforation 10.7 ESR1 PGR TP53
40 ovarian mesodermal adenosarcoma 10.7 ESR1 PGR TP53
41 chest wall lymphoma 10.7 ESR1 PGR TP53
42 avoidant personality disorder 10.7 ESR1 KLK3 PGR
43 malt worker's lung 10.6 KLK3 TP53
44 mediastinum rhabdomyosarcoma 10.6 KIT PGR TP53
45 pancreatic agenesis 10.6 KIT KLK3 TP53
46 mesenchymoma 10.6 KIT KRT20 PGR TP63
47 otitis externa 10.6 ERBB2 PGR TP53
48 fallopian tube squamous cell carcinoma 10.6 KIT KRT5 TP53
49 brenner tumor of the vagina 10.6 ERBB2 ESR1 TP53
50 brenner tumor of ovary 10.6 ERBB2 ESR1 TP53

Graphical network of the top 20 diseases related to Cribriform Carcinoma:



Diseases related to Cribriform Carcinoma

Symptoms & Phenotypes for Cribriform Carcinoma

GenomeRNAi Phenotypes related to Cribriform Carcinoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death HMECs cells GR00103-A-0 9.1 EIF3A IRS1 KLK3 PGR PIP TP53

MGI Mouse Phenotypes related to Cribriform Carcinoma:

44 (show all 16)
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.39 NKX2-1 PGR PIP PPP3R1 TP53 TP63
2 cellular MP:0005384 10.38 TP53 TP63 CD36 ERBB2 ESR1 FUT4
3 behavior/neurological MP:0005386 10.3 KIT KRT5 NKX2-1 PGR PPP3R1 TP53
4 homeostasis/metabolism MP:0005376 10.29 ESR1 HSD11B2 IRS1 KIT KRT7 KRT8
5 digestive/alimentary MP:0005381 10.26 CD36 ERBB2 ESR1 HSD11B2 KIT KRT5
6 endocrine/exocrine gland MP:0005379 10.24 CD36 ERBB2 ESR1 IRS1 KIT NKX2-1
7 mortality/aging MP:0010768 10.22 CD36 ERBB2 ESR1 HSD11B2 IRS1 KIT
8 immune system MP:0005387 10.2 CD36 ESR1 FUT4 IRS1 KIT KRT8
9 embryo MP:0005380 10.11 ERBB2 ESR1 KIT KRT8 PGR PPP3R1
10 limbs/digits/tail MP:0005371 10.03 TP63 ERBB2 ESR1 IRS1 KIT KRT5
11 muscle MP:0005369 10.02 CD36 ERBB2 ESR1 HSD11B2 IRS1 KIT
12 neoplasm MP:0002006 9.92 ERBB2 ESR1 HSD11B2 KIT NKX2-1 PGR
13 no phenotypic analysis MP:0003012 9.86 ESR1 HSD11B2 KIT KRT5 NKX2-1 PGR
14 renal/urinary system MP:0005367 9.76 CD36 ESR1 HSD11B2 KIT KRT7 PPP3R1
15 reproductive system MP:0005389 9.61 ERBB2 ESR1 KIT KRT8 NKX2-1 PGR
16 skeleton MP:0005390 9.28 ESR1 IRS1 KIT NKX2-1 PGR TP53

Drugs & Therapeutics for Cribriform Carcinoma

Drugs for Cribriform Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 161)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
2
Cevimeline Approved Phase 3 107233-08-9 83898 25137844
3
Fluconazole Approved Phase 2, Phase 3 86386-73-4 3365
4
Miconazole Approved, Investigational, Vet_approved Phase 2, Phase 3,Phase 1 22916-47-8 4189
5
Doxepin Approved Phase 3 1668-19-5 667477 667468
6
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774
7
Megestrol acetate Approved, Vet_approved Phase 3 595-33-5 11683
8 Pancreatic Polypeptide Investigational Phase 3,Phase 1 59763-91-6
9
Docetaxel Approved May 1996, Investigational Phase 3,Phase 2,Phase 1 114977-28-5 148124 9877265
10 Liver Extracts Phase 3,Phase 2,Phase 1
11 Alkylating Agents Phase 3,Phase 2,Phase 1
12 Anti-Infective Agents Phase 2, Phase 3,Phase 1
13 Cytochrome P-450 Enzyme Inhibitors Phase 2, Phase 3
14 Adjuvants, Anesthesia Phase 3
15 Analgesics Phase 3
16 Analgesics, Opioid Phase 3
17 Anesthetics Phase 3
18 Anesthetics, General Phase 3
19 Anesthetics, Intravenous Phase 3
20 Central Nervous System Depressants Phase 3
21 Narcotics Phase 3
22 Peripheral Nervous System Agents Phase 3
23 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
24 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
25 Mitomycins Phase 3
26 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 1,Phase 2
27 Porfiromycin Phase 3
28 Autonomic Agents Phase 3
29 Cholinergic Agents Phase 3
30 Neurotransmitter Agents Phase 3
31 Antifungal Agents Phase 2, Phase 3,Phase 1
32 Cytochrome P-450 CYP2C9 Inhibitors Phase 2, Phase 3
33 Hormone Antagonists Phase 2, Phase 3
34 Hormones Phase 2, Phase 3,Phase 1
35 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3
36 Steroid Synthesis Inhibitors Phase 2, Phase 3
37 Antidepressive Agents Phase 3
38 Antidepressive Agents, Tricyclic Phase 3
39 Histamine Antagonists Phase 3
40
Histamine Phosphate Phase 3 51-74-1 65513
41 Psychotropic Drugs Phase 3
42 Antineoplastic Agents, Hormonal Phase 3
43 Appetite Stimulants Phase 3
44 Central Nervous System Stimulants Phase 3
45 Contraceptive Agents Phase 3
46 Contraceptives, Oral Phase 3
47
Megestrol Phase 3 3562-63-8 19090 3080587
48 Antimitotic Agents Phase 3,Phase 2,Phase 1
49 Cola Nutraceutical Phase 3,Phase 2,Phase 1
50
Cetuximab Approved Phase 1, Phase 2 205923-56-4 56842117 2333

Interventional clinical trials:

(show top 50) (show all 110)

id Name Status NCT ID Phase Drugs
1 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
2 Radiation Therapy and Chemotherapy in Treating Patients With Head and Neck Cancer Completed NCT00002507 Phase 3 mitomycin C;porfiromycin
3 Acupuncture or Standard Therapy in Treating Pain and Dysfunction in Patients Who Have Undergone Neck Surgery for Head and Neck Cancer Completed NCT00090337 Phase 3
4 Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer Completed NCT00017511 Phase 3 cevimeline hydrochloride
5 Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer Completed NCT00002533 Phase 2, Phase 3 fluconazole
6 Study of Nutrition Regimens in Treating Patients With Cancer of the Upper Aerodigestive Tract Completed NCT00765440 Phase 3
7 Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy Completed NCT01156142 Phase 3 doxepin hydrochloride
8 Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck Cancer Completed NCT00006799 Phase 3 megestrol acetate
9 Docetaxel and St. John's Wort in Treating Patients With Solid Tumors That Cannot Be Removed By Surgery Withdrawn NCT00041171 Phase 3 Hypericum perforatum;docetaxel
10 Study of Imatinib (Glivec) in Patients With Adenoid Cystic Carcinoma of the Head and Neck Unknown status NCT00180921 Phase 2 Imatinib
11 Adenoid Cystic Carcinoma, Erbitux, and Particle Therapy Unknown status NCT01192087 Phase 1, Phase 2 Cetuximab
12 External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases Unknown status NCT00637637 Phase 2 indinavir sulfate;ritonavir
13 A Study of Sunitinib in Recurrent and/or Metastatic Adenoid Cystic Carcinoma of the Salivary Glands Completed NCT00886132 Phase 2 Sunitinib
14 Phase II Trial of Doxorubicin and Bortezomib in Patients With Incurable Adenoid Cystic Carcinoma of the Head and Neck Completed NCT00581360 Phase 2 doxorubicin and bortezomib
15 Study of RAD001 in Adenoid Cystic Carcinoma Completed NCT01152840 Phase 2 RAD001
16 Axitinib (AG-013736) in Patients With Progressive, Recurrent/Metastatic Adenoid Cystic Carcinoma Completed NCT01558661 Phase 2 AG-013736 (AXITINIB)
17 Dovitinib in Adenoid Cystic Carcinoma Completed NCT01417143 Phase 2 TKI258 (Dovitinib):
18 Study of Dovitinib (TKI258) in Adenoid Cystic Carcinoma Completed NCT01524692 Phase 2 Dovitinib (TKI258)
19 A Phase II Study of Dovitinib in Recurrent and/or Metastatic Adenoid Cystic Carcinoma of the Salivary Glands Completed NCT01678105 Phase 2 Dovitinib
20 Bortezomib Followed by the Addition of Doxorubicin at Disease Progression in Treating Patients With Locally Advanced, Recurrent, or Metastatic Adenoid Cystic Carcinoma (Cancer) of the Head and Neck Completed NCT00077428 Phase 2 bortezomib;doxorubicin hydrochloride
21 Gemcitabine in Treating Patients With Recurrent or Metastatic Adenoid Cystic Cancer of the Head and Neck Completed NCT00017498 Phase 2 gemcitabine hydrochloride
22 Lapatinib in Treating Patients With Recurrent and/or Metastatic Adenoid Cystic Cancer or Other Salivary Gland Cancers Completed NCT00095563 Phase 2 lapatinib ditosylate
23 Imatinib Mesylate in Treating Patients With Salivary Gland Cancer Completed NCT00045669 Phase 2 imatinib mesylate
24 Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer Completed NCT00492089 Phase 2 bevacizumab;placebo
25 Erlotinib and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney, Colorectal, Head and Neck, Pancreatic, or Non-Small Cell Lung Cancer Completed NCT00101348 Phase 1, Phase 2 erlotinib hydrochloride
26 High-dose ICE With Amifostine Completed NCT00003657 Phase 2 Amifostine;Carboplatin;Etoposide;Ifosfamide
27 Docetaxel in Treating Patients With Solid Tumors Completed NCT00003565 Phase 2 docetaxel
28 Chemotherapy in Treating Patients With Solid Tumors Completed NCT00003103 Phase 1, Phase 2 docetaxel
29 Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Mouth Cancer Completed NCT00004901 Phase 1, Phase 2 ethynyluracil;fluorouracil;hydroxyurea
30 Oxaliplatin and Capecitabine in Treating Patients With Relapsed or Metastatic Head and Neck Cancer Completed NCT00448552 Phase 2 capecitabine;oxaliplatin
31 Epirubicin, Carboplatin, and Capecitabine in Treating Patients With Unresectable Locally Advanced, Metastatic, or Recurrent Solid Tumor Completed NCT00021047 Phase 1, Phase 2 capecitabine;carboplatin;epirubicin hydrochloride
32 Vaccine Therapy Plus Biological Therapy in Treating Adults With Metastatic Solid Tumors Completed NCT00019331 Phase 2 DetoxPC
33 Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases Completed NCT00154388 Phase 2 Imatinib mesylate
34 Cisplatin or Carboplatin Combined With Gemcitabine in Treating Patients With Locally Advanced, Recurrent, or Metastatic Malignant Salivary Gland Tumor Completed NCT00079079 Phase 2 carboplatin;cisplatin;gemcitabine hydrochloride
35 Trastuzumab in Treating Patients With Advanced Salivary Gland Cancer Completed NCT00004163 Phase 2 Trastuzumab
36 Gemcitabine in Treating Patients With Advanced Salivary Gland Cancer That Cannot Be Removed During Surgery Completed NCT00003744 Phase 2 gemcitabine
37 Gemcitabine and Doxorubicin in Treating Patients With Recurrent or Progressive Head and Neck Cancer Completed NCT00509665 Phase 2 doxorubicin hydrochloride;gemcitabine hydrochloride
38 Paclitaxel and Cisplatin Plus Radiation Therapy Followed by Filgrastim in Treating Patients With Recurrent Head and Neck Cancer or Lung Cancer Completed NCT00021333 Phase 2 cisplatin;paclitaxel
39 Chidamide for Advanced Cephalic and Cervical Adenocystic Carcinoma: Evaluation of Efficiency and Safety Recruiting NCT02883374 Phase 2 Chidamide
40 Pembrolizumab With or Without Radiation in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma Recruiting NCT03087019 Phase 2 Pembrolizumab
41 A Study of Apatinib in Recurrent/Metastatic Adenoid Cystic Carcinoma of the Head and Neck Recruiting NCT02775370 Phase 2 Apatinib Mesylate
42 Study of Axitinib in Patients With Recurred or Metastatic Adenoid Cystic Carcinoma Recruiting NCT02859012 Phase 2 Axitinib
43 Nivolumab and Ipilimumab in Treating Patients With Metastatic Recurrent Major or Minor Salivary Gland Cancer Recruiting NCT03146650 Phase 2
44 Study of Nivolumab Plus Ipilimumab in Patients With Salivary Gland Cancer Recruiting NCT03172624 Phase 2 Nivolumab;Ipilimumab
45 Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers Recruiting NCT02978625 Phase 2
46 A Clinical Trial of Endoscopic Surgery Followed by Chemotherapy and Proton Radiation for the Treatment of Tumors in the Sinus and Nasal Passages Recruiting NCT03274414 Phase 2 Cisplatin
47 18F FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy Recruiting NCT01806675 Phase 1, Phase 2 fludeoxyglucose F 18;2-fluoropropionyl-labeled pegylated dimeric RGD peptide
48 Regorafenib in Patients With Progressive, Recurrent/Metastatic Adenoid Cystic Carcinoma Active, not recruiting NCT02098538 Phase 2 Regorafenib
49 Testing Lenvatinib in Patients With Adenoid Cystic Carcinoma Active, not recruiting NCT02780310 Phase 2 Lenvatinib
50 Lenvatinib in Recurrent and/or Metastatic Adenoid Cystic Carcinomas of the Salivary Glands: ACC-LEN14 Active, not recruiting NCT02860936 Phase 2 Lenvatinib

Search NIH Clinical Center for Cribriform Carcinoma

Genetic Tests for Cribriform Carcinoma

Anatomical Context for Cribriform Carcinoma

MalaCards organs/tissues related to Cribriform Carcinoma:

39
Salivary Gland, Breast, Lung, Brain, Skin, Liver, Kidney

Publications for Cribriform Carcinoma

Articles related to Cribriform Carcinoma:

(show all 32)
id Title Authors Year
1
Evaluation and comparison of radiologic-pathologic findings in invasive cribriform carcinoma of the breast. ( 28618754 )
2017
2
A solid variant of primary cutaneous cribriform carcinoma: a small, stable, long-term lesion. ( 28508756 )
2017
3
Primary Cribriform Carcinoma of the Eyelid With Neuroendocrine Features: A Case Report. ( 28300861 )
2017
4
Primary Cutaneous Cribriform Carcinoma Treated With Mohs Micrographic Surgery. ( 28872559 )
2017
5
Invasive cribriform carcinoma of the breast: A report of nine cases and a review of the literature. ( 25789036 )
2015
6
Clinicopathological Characteristics and Survival Outcomes of Invasive Cribriform Carcinoma of Breast: A SEER Population-Based Study. ( 26252312 )
2015
7
Primary cutaneous cribriform carcinoma: report of six cases with clinicopathologic data and immunohistochemical profile. ( 25732813 )
2015
8
Colonic Cribriform Carcinoma, a Morphologic Pattern Associated With Low Survival. ( 25015669 )
2014
9
Prognostic impact of intraductal carcinoma and large cribriform carcinoma architecture after prostatectomy in a contemporary cohort. ( 24703897 )
2014
10
Invasive cribriform carcinoma of the breast: mammographic, sonographic, MRI, and 18a88F-FDG PET-CT features. ( 24938660 )
2014
11
Invasive cribriform carcinoma in a Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified. ( 23412348 )
2013
12
Cribriform carcinoma mimicking breast abscess - case report. Diagnostic and therapeutic management. ( 26674469 )
2013
13
A pure invasive cribriform carcinoma of the breast with bone metastasis if untreated for thirteen years: a case report and literature review. ( 23167837 )
2012
14
Invasive cribriform carcinoma arising in malignant phyllodes tumor of breast: a case report. ( 23110003 )
2012
15
Primary cutaneous cribriform carcinoma of the neck: a case report. ( 23316623 )
2012
16
Sonographic findings of invasive cribriform carcinoma of the breast. ( 21527619 )
2011
17
Cutaneous cribriform carcinoma: a short comment. ( 21315957 )
2011
18
Grading of invasive cribriform carcinoma on prostate needle biopsy: an interobserver study among experts in genitourinary pathology. ( 18724248 )
2008
19
Cribriform carcinoma of the gallbladder: a clinicopathologic study of 7 cases. ( 18769339 )
2008
20
Immunohistochemical phenotype of cutaneous cribriform carcinoma with a panel of 15 antibodies. ( 18085381 )
2007
21
Report on a case of pure cribriform carcinoma of the breast with internal mammary node metastasis: description of the case and review of the literature. ( 16869243 )
2006
22
Invasive cribriform carcinoma with extensive microcalcifications in the male breast. ( 15858447 )
2005
23
Primary cutaneous cribriform carcinoma: a rare apocrine tumour. ( 16115058 )
2005
24
A case report of cribriform carcinoma of the pancreas with long time survival. ( 11268983 )
2001
25
Fine needle aspiration cytology of invasive cribriform carcinoma of the breast with osteoclastlike giant cells: a case report. ( 11480724 )
2001
26
Cribriform carcinoma of the prostate and cribriform prostatic intraepithelial neoplasia: incidence and clinical implications. ( 9669346 )
1998
27
Infiltrating cribriform carcinoma of the breast. A clinico-pathologic and immunohistochemical study of 5 cases. ( 8780923 )
1996
28
The radiological appearances of invasive cribriform carcinoma of the breast. Nottingham Breast Team. ( 7955831 )
1994
29
Fine needle aspiration of invasive cribriform carcinoma with benign osteoclast-like giant cells of histiocytic origin. A case report. ( 8191846 )
1994
30
Light and electron microscopic study of an invasive cribriform carcinoma with extensive microcalcification developing in a breast with silicone augmentation. ( 7810003 )
1994
31
Infiltrating cribriform carcinoma of the breast: a distinctive clinicopathologic entity. ( 2312110 )
1990
32
Invasive cribriform carcinoma of the breast. ( 6884999 )
1983

Variations for Cribriform Carcinoma

Expression for Cribriform Carcinoma

Search GEO for disease gene expression data for Cribriform Carcinoma.

Pathways for Cribriform Carcinoma

GO Terms for Cribriform Carcinoma

Cellular components related to Cribriform Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.92 KRT20 KRT5 KRT7 KRT8

Biological processes related to Cribriform Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.67 KRT20 KRT5 KRT7 KRT8
2 regulation of phosphatidylinositol 3-kinase signaling GO:0014066 9.65 ERBB2 IRS1 KIT
3 epithelial cell development GO:0002064 9.46 ESR1 TP63
4 cornification GO:0070268 9.46 KRT20 KRT5 KRT7 KRT8
5 mitotic G1 DNA damage checkpoint GO:0031571 9.43 TP53 TP63
6 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:1900740 9.43 PPP3R1 TP53 TP63
7 positive regulation of phospholipase C activity GO:0010863 9.4 ESR1 KIT
8 phosphatidylinositol-mediated signaling GO:0048015 9.26 ERBB2 IRS1 KIT TP53
9 regulation of toll-like receptor signaling pathway GO:0034121 9.02 ESR1
10 positive regulation of gene expression GO:0010628 9.02 ERBB2 KIT NKX2-1 PIP TP53

Molecular functions related to Cribriform Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.91 CD36 EIF3A ERBB2 ESR1 IRS1 IRS4
2 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.33 ERBB2 IRS1 KIT
3 signal transducer, downstream of receptor, with protein tyrosine kinase activity GO:0004716 9.26 ERBB2 KIT
4 steroid binding GO:0005496 8.8 ESR1 HSD11B2 PGR

Sources for Cribriform Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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