Crimean-Congo Hemorrhagic Fever (CCHF) malady

Disease Ontology:⁸ A viral infectious disease that is a hemorrhagic fever, has material basis in crimean-congo hemorrhagic fever virus, which is transmitted by hyalomma ticks. the infection has symptom headache, has symptom high fever, has symptom back pain, has symptom joint pain, has symptom stomach pain, has symptom vomiting, has symptom red eyes, has symptom flushed face, has symptom red throat, has symptom petechiae (red spots) on the palate, has symptom jaundice, has symptom nosebleeds, and has symptom blood in the feces and urine.

MalaCards: Crimean-Congo Hemorrhagic Fever, also known as crimean hemorrhagic fever, is related to thrombocytopenia and hemorrhagic fever, and has symptoms including nausea/vomiting/regurgitation/merycism/hyperemesis, collapse/sudden death/cardiac arrest/cardiorespiratory arrest and early death/lethality. An important gene associated with Crimean-Congo Hemorrhagic Fever is CHIT1 (chitinase 1 (chitotriosidase)), and among its related pathways are Leishmaniasis and Legionellosis. The compounds cycloheximide and prednisolone have been mentioned in the context of this disorder. Affiliated tissues include heart, monocytes and endothelial, and related mouse phenotypes are respiratory system and muscle.

CDC:³ Crimean-Congo hemorrhagic fever (CCHF) is caused by infection with a tick-borne virus (Nairovirus) in the family Bunyaviridae. The disease was first characterized in the Crimea in 1944 and given the name Crimean hemorrhagic fever. It was then later recognized in 1969 as the cause of illness in the Congo, thus resulting in the current name of the disease.

External Ids:

Disease Ontology8 DOID:12287 MeSH35 D006479 NCIt40 C34682 ICD9CM27 065.0 SNOMED-CT57 43489008

ICD10 via Orphanet26 A98.0 SNOMED-CT via Orphanet58 43489008 ICD1025 A98.0 UMLS61 C0019099

Symptoms:

⁴⁹ (show all 37)

nausea/vomiting/regurgitation/merycism/hyperemesis collapse/sudden death/cardiac arrest/cardiorespiratory arrest early death/lethality asthenia/fatigue/weakness fever/chilling hepatitis/icterus/cholestasis cutaneous rash thoracic/chest pain cough myalgia/muscular pain acute abdominal pain/colic gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia gingivorrhagia/gingival bleeding thrombocytopenia/thrombopenia facial pain/cephalalgia/migraine purpura/petichiae abnormal hepatic enzymes/transaminases pharyngitis epistaxis/nose bleeding

hemorrhage/hemorrhagic syndrome/excessive/long-lasting bleeding chronic uveitis/blepharitis/episcleritis/scleritis/conjonctivitis/keratitis acute diarrhea leukopenia/hypoleukocytosis liver/hepatic steatosis headache jaundice vomiting joint pain nosebleeds back pain stomach pain red eyes high fever flushed face red throat petechiae (red spots) on the palate blood in the feces

Search GEO for disease gene expression data for Crimean-Congo Hemorrhagic Fever.