MCID: CRM001
MIFTS: 54

Crimean-Congo Hemorrhagic Fever malady

Categories: Genetic diseases, Infectious diseases, Rare diseases, Skin diseases

Aliases & Classifications for Crimean-Congo Hemorrhagic Fever

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Sources:
2CDC, 11Disease Ontology, 13DISEASES, 29ICD10, 30ICD10 via Orphanet, 31ICD9CM, 38MeSH, 44NCIt, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS
See all MalaCards sources

Aliases & Descriptions for Crimean-Congo Hemorrhagic Fever:

Name: Crimean-Congo Hemorrhagic Fever 11 53 2 13
Hemorrhagic Fever, Crimean 38 67
Crimean Hemorrhagic Fever 11 53
Congo Hemorrhagic Fever 53 67
Cchf 53 2
 
Congo-Crimean Hemorrhagic Fever 11
Hemorrhagic Fever Crimean-Congo 49
Chf Congo Virus 11
Congo Fever 53

Characteristics:

Orphanet epidemiological data:

53
crimean-congo hemorrhagic fever:
Age of onset: All ages; Age of death: any age

Classifications:



External Ids:

Disease Ontology11 DOID:12287
ICD1029 A98.0
ICD9CM31 065.0
MeSH38 D006479
SNOMED-CT61 43489008
NCIt44 C34682
Orphanet53 ORPHA99827
ICD10 via Orphanet30 A98.0

Summaries for Crimean-Congo Hemorrhagic Fever

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Disease Ontology:11 A viral infectious disease that is a hemorrhagic fever, has material basis in Crimean-Congo hemorrhagic fever virus, which is transmitted by Hyalomma ticks. The infection has symptom headache, has symptom high fever, has symptom back pain, has symptom joint pain, has symptom stomach pain, has symptom vomiting, has symptom red eyes, has symptom flushed face, has symptom red throat, has symptom petechiae (red spots) on the palate, has symptom jaundice, has symptom nosebleeds, and has symptom blood in the feces and urine.

MalaCards based summary: Crimean-Congo Hemorrhagic Fever, also known as hemorrhagic fever, crimean, is related to hemophagocytic lymphohistiocytosis and malaria, and has symptoms including abnormality of temperature regulation, skin rash and hepatic steatosis. An important gene associated with Crimean-Congo Hemorrhagic Fever is F3 (Coagulation Factor III, Tissue Factor), and among its related pathways are Cytokines and Inflammatory Response and African trypanosomiasis. Affiliated tissues include eye, skin and testes, and related mouse phenotypes are digestive/alimentary and cardiovascular system.

Related Diseases for Crimean-Congo Hemorrhagic Fever

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Diseases related to Crimean-Congo Hemorrhagic Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 153)
idRelated DiseaseScoreTop Affiliating Genes
1hemophagocytic lymphohistiocytosis30.5IL6, TNF
2malaria28.5CXCL10, F3, IL6, TNF, VEGFA
3hemorrhagic fever11.4
4idiopathic central precocious puberty10.4F3, TNF
5chronic diarrhea due to guanylate cyclase 2c overactivity10.4F3, IL6
6panner disease10.4IL6, TNF
7aortic arch interruption10.4IL6, TNF
8maligant granulosa cell tumor of ovary10.4IL6, TNF
9hemometra10.4IL6, TNF
10tricho odonto onycho dermal syndrome10.4IL6, TNF
11scrotum paget's disease10.4IL6, TNF
12epstein-barr virus hepatitis10.4IL6, TNF
13abdominal chemodectomas with cutaneous angiolipomas10.4IL6, TNF
14antigen-peptide-transporter 2 deficiency10.4IL6, TNF
15hypothyroidism10.4IL6, TNF
16ethmoid sinus adenoid cystic carcinoma10.4IL6, TNF
17splenic manifestation of prolymphocytic leukemia10.4IL6, TNF
18post-infectious myocarditis10.4IL6, TNF
19skin disease10.4IL6, TNF
20pasteurellosis10.4IL6, TNF
21scarlet fever10.4IL6, TNF
22lymphocytic colitis10.4IL6, TNF
23non-secretory myeloma10.4IL6, TNF
24idiopathic neutropenia10.4F3, IL6
25tonsillar fossa cancer10.4CASP3, IL6
26sweat gland cancer10.4F3, IL6
27qualitative platelet defect10.4IL6, TNF
28sterility due to immotile flagella10.4IL6, TNF
29islet cell tumor10.4IL6, TNF
30rift valley fever10.4
31ulcerative colitis10.4CASP3, IL6
32orbital lymphangioma10.4IL6, TNF
33cauda equina syndrome10.4IL6, TNF
34renal cell carcinoma 410.4IL6, TNF
35nondystrophic myotonia10.4GPT, TNF
36paraneoplastic polyneuropathy10.3IL6, TNF
37thoracic aortic aneurysm10.3IL6, TNF
38steatorrhea10.3CXCL10, TNF
39epididymis adenomatoid tumor10.3IL6, TNF
40primary biliary cirrhosis10.3IL6, TNF
41colon carcinoma in situ10.3F3, IL6
42ampulla of vater neoplasm10.3IL6, TNF
43leukostasis10.3IL6, TNF
44mechanical lagophthalmos10.3IL6, TNF
45oral candidiasis10.3IL6, TNF
46foodborne botulism10.3IL6, TNF
47psychologic dyspareunia10.3CXCL10, TNF
48gastroduodenal crohn's disease10.3IL6, TNF
49substernal goiter10.3CXCL10, IL6
50endotheliitis10.3

Graphical network of the top 20 diseases related to Crimean-Congo Hemorrhagic Fever:



Diseases related to crimean-congo hemorrhagic fever

Symptoms for Crimean-Congo Hemorrhagic Fever

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Symptoms:

 11 (show all 13)
  • headache
  • high fever
  • back pain
  • joint pain
  • stomach pain
  • vomiting
  • red eyes
  • flushed face
  • red throat
  • petechiae (red spots) on the palate
  • jaundice
  • nosebleeds
  • blood in the feces

Human phenotypes related to Crimean-Congo Hemorrhagic Fever:

 63 53 (show all 29)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 abnormality of temperature regulation63 hallmark (90%) HP:0004370
2 skin rash63 53 typical (50%) Frequent (79-30%) HP:0000988
3 hepatic steatosis63 53 typical (50%) Frequent (79-30%) HP:0001397
4 subcutaneous hemorrhage63 typical (50%) HP:0001933
5 diarrhea63 53 typical (50%) Frequent (79-30%) HP:0002014
6 nausea and vomiting63 53 typical (50%) Frequent (79-30%) HP:0002017
7 abdominal pain63 53 typical (50%) Frequent (79-30%) HP:0002027
8 migraine63 typical (50%) HP:0002076
9 elevated hepatic transaminases63 53 typical (50%) Frequent (79-30%) HP:0002910
10 myalgia63 53 typical (50%) Frequent (79-30%) HP:0003326
11 inflammatory abnormality of the eye63 typical (50%) HP:0100533
12 recurrent pharyngitis63 53 typical (50%) Frequent (79-30%) HP:0100776
13 gingival bleeding63 53 occasional (7.5%) Occasional (29-5%) HP:0000225
14 epistaxis63 53 occasional (7.5%) Occasional (29-5%) HP:0000421
15 sudden cardiac death63 occasional (7.5%) HP:0001645
16 thrombocytopenia63 53 occasional (7.5%) Occasional (29-5%) HP:0001873
17 leukopenia63 53 occasional (7.5%) Occasional (29-5%) HP:0001882
18 abnormality of coagulation63 occasional (7.5%) HP:0001928
19 gastrointestinal hemorrhage63 53 occasional (7.5%) Occasional (29-5%) HP:0002239
20 chest pain63 53 occasional (7.5%) Occasional (29-5%) HP:0100749
21 uveitis53 Frequent (79-30%)
22 jaundice53 Occasional (29-5%)
23 petechiae53 Frequent (79-30%)
24 abnormal bleeding53 Occasional (29-5%)
25 fever53 Very frequent (99-80%)
26 headache53 Frequent (79-30%)
27 cardiorespiratory arrest53 Occasional (29-5%)
28 fatigue53 Very frequent (99-80%)
29 cough53 Frequent (79-30%)

UMLS symptoms related to Crimean-Congo Hemorrhagic Fever:


hemoptysis, cullen's sign, traumatic hematuria, mucosal haemorrhage, nail bed hemorrhage

Drugs & Therapeutics for Crimean-Congo Hemorrhagic Fever

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Drugs for Crimean-Congo Hemorrhagic Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
RibavirinapprovedPhase 298436791-04-537542
Synonyms:
1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide
36791-04-5
437710-49-1
66510-90-5
AA-504/07617051
AB00430481
AC1L1XXZ
AC1Q1IDC
AC1Q4ZGS
AKOS001715163
BB_NC-0567
BPBio1_001195
BRN 0892462
BSPBio_001085
BSPBio_003352
C-Virin
CHEMBL1643
CID37542
Copegus
Copegus (TN)
Cotronak
D00423
DB00811
DRG-0028
DivK1c_000782
Drug: Ribavirin
EU-0101063
FT-0082885
HMS2090L15
HMS2094O09
HMS502H04
HSDB 6513
ICN-1229
IDI1_000782
KBio1_000782
KBio2_002328
KBio2_004896
KBio2_007464
KBio3_002854
KBioGR_001804
KBioSS_002331
KS-1104
LS-1241
Lopac0_001063
MLS000028486
MLS002222317
MolPort-002-507-104
MolPort-002-885-856
NCGC00090726-01
NCGC00090726-03
NCGC00090726-04
NCGC00090726-05
NCGC00090726-06
NCGC00090726-07
NINDS_000782
NSC 163039
 
NSC163039
Prestwick3_000993
R 9644
R-964
R9644_SIGMA
RBV
RG-964
RIBAV
RTC
RTCA
RTP
Ravanex
Rebetol
Rebetol (TN)
Rebetron
Rebretron
Ribacine
Ribamide
Ribamidil
Ribamidyl
Ribasphere
Ribasphere (TN)
Ribav
Ribavirin
Ribavirin (JAN/USP/INN)
Ribavirin Capsules
Ribavirin Triphosphate
Ribavirin [USAN:INN]
Ribavirin-TP
Ribavirina
Ribavirina [INN-Spanish]
Ribavirine
Ribavirine [INN-French]
Ribavirinum
Ribavirinum [INN-Latin]
Ribovirin
Ro 20-9963/000
Ro-20-9963
S2504_Selleck
SCH 18908
SMP1_000261
SMR000058315
SPECTRUM1503938
SR-01000076112-3
Spectrum3_001876
Spectrum4_001252
Spectrum5_002075
Spectrum_001826
Tribavirin
UNII-49717AWG6K
Varazid
Vilona
Viramid
Viramide
Virazid
Virazide
Virazole
Virazole (Ribavirin) Inhalation Solution
Virazole (TN)
Virazole 5'-triphosphate
ZINC01035331
ribavirin
2AntimetabolitesPhase 211774
3Anti-Infective AgentsPhase 221402
4Antiviral AgentsPhase 29732
5
Formaldehydeapproved, vet_approvedPhase 18450-00-0712
Synonyms:
Aldeide formica
Fannoform
Formaldehyde
Formalin
Formalina
Formaline
Formalith
Formic aldehyde
Formol
 
Methaldehyde
Methanal
Methyl aldehyde
Methylene glycol
Methylene oxide
Oxomethane
Oxomethylene
Oxymethylene
Paraform
Paraformaldehyde
6VaccinesPhase 16428
7Pharmaceutical SolutionsPhase 17793

Interventional clinical trials:

idNameStatusNCT IDPhase
1Treatment of Viral Hemorrhagic Fevers With Intravenous Ribavirin in Military Treatment FacilitiesEnrolling by invitationNCT00992693Phase 2
2Phase I Study to Evaluate Basic Pharmacodynamic, Pharmacological and Toxicological Effects of the Newly Developed Crimean-Congo Hemorrhagic Fever Vaccine for HumansActive, not recruitingNCT03020771Phase 1
3Cohort of Patients Infected by an ArbovirusRecruitingNCT01099852
4Intravenous Ribavirin Protocol to Treat Individuals With Viral Hemorrhagic FeverNot yet recruitingNCT02483260

Search NIH Clinical Center for Crimean-Congo Hemorrhagic Fever


Cochrane evidence based reviews: hemorrhagic fever, crimean

Genetic Tests for Crimean-Congo Hemorrhagic Fever

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Anatomical Context for Crimean-Congo Hemorrhagic Fever

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MalaCards organs/tissues related to Crimean-Congo Hemorrhagic Fever:

35
Eye, Skin, Testes, Endothelial, Heart, Neutrophil

Animal Models for Crimean-Congo Hemorrhagic Fever or affiliated genes

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MGI Mouse Phenotypes related to Crimean-Congo Hemorrhagic Fever:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.6CASP3, IL6, NFKB1, TNF, VEGFA
2MP:00053858.4CASP3, CXCL10, F3, IL6, TNF, VEGFA
3MP:00107718.2CASP3, F3, IL6, NFKB1, TNF, VEGFA
4MP:00053698.2CASP3, F3, IL6, NFKB1, TNF, VEGFA
5MP:00053847.8CASP3, CXCL10, F3, IL6, NFKB1, TNF
6MP:00053887.8CASP3, IL6, NFKB1, TNF, VEGFA
7MP:00036317.7CASP3, CXCL10, F3, IL6, NFKB1, TNF
8MP:00053767.4CASP3, CXCL10, F3, IL6, NFKB1, TLR8
9MP:00053877.4CASP3, CXCL10, F3, IL6, NFKB1, TLR8
10MP:00053976.9CASP3, CXCL10, F3, GPT, IL6, NFKB1

Publications for Crimean-Congo Hemorrhagic Fever

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Articles related to Crimean-Congo Hemorrhagic Fever:

(show top 50)    (show all 498)
idTitleAuthorsYear
1
Crimean-Congo hemorrhagic fever among children in Iran. (27878461)
2016
2
Does Crimean-Congo Hemorrhagic Fever Cause a Vasculitic Reaction with Pulmonary Artery Enlargement and Acute Pulmonary Hypertension? (27344326)
2016
3
Crimean-Congo Hemorrhagic Fever in Dubai, United Arab Emirates, 2010: Case Report. (27795839)
2016
4
Possible sexual transmission of Crimean-Congo hemorrhagic fever. (26972040)
2016
5
Crimean-Congo hemorrhagic fever - A ticking bomb? (27044612)
2016
6
Crimean-Congo hemorrhagic fever virus lineages Europe 1 and Europe 2 in Bulgarian ticks. (27378409)
2016
7
Clinical significance of neutrophil gelatinase-associated lipocalin in Crimean-Congo hemorrhagic Fever. (25685783)
2015
8
Fiber-optic immunosensor for detection of Crimean-Congo hemorrhagic fever IgG antibodies in patients. (26151547)
2015
9
Emergence of Crimean-Congo hemorrhagic fever. (26464230)
2015
10
A novel AP92-like Crimean-Congo hemorrhagic fever virus strain, Greece. (24953797)
2014
11
Prevalence of crimean-congo hemorrhagic Fever virus in healthy population, livestock and ticks in kosovo. (25393542)
2014
12
Serosurvey of Crimean-Congo hemorrhagic fever virus in domestic animals, Gujarat, India, 2013. (25229708)
2014
13
Seroprevalence of Crimean-Congo hemorrhagic fever in southeastern Bulgaria. (25241694)
2014
14
Genetic characterization and molecular clock analyses of the Crimean-Congo hemorrhagic fever virus from human and ticks in India, 2010-2011. (23195573)
2013
15
Evaluation of renal involvement in children with Crimean-Congo hemorrhagic fever. (24270136)
2013
16
Influence of laboratory animal hosts on the life cycle of Hyalomma marginatum and implications for an in vivo transmission model for Crimean-Congo hemorrhagic fever virus. (23971007)
2013
17
Temporal modeling of Crimean-Congo hemorrhagic fever in eastern Iran. (23474177)
2013
18
Bayesian phylogeography of crimean-congo hemorrhagic Fever virus in europe. (24223988)
2013
19
Hemorrhagic fever with renal syndrome and Crimean-Congo hemorrhagic fever as causes of acute undifferentiated febrile illness in Bulgaria. (23421884)
2013
20
Comparative study between Ribavirin and Ribavirin plus Intravenous Immunoglobulin against Crimean Congo hemorrhagic fever. (24250699)
2013
21
Factors associated with IgG positivity to Crimean-Congo hemorrhagic fever virus in the area with the highest seroprevalence in Greece. (23831367)
2013
22
Guineafowl, ticks and Crimean-Congo hemorrhagic fever in Turkey: the perfect storm? (23206535)
2013
23
Hepatocyte pathway alterations in response to in vitro Crimean Congo hemorrhagic fever virus infection. (24184319)
2013
24
Bradycardia seen in children with Crimean-Congo hemorrhagic fever. (24107209)
2013
25
Relationship between Crimean-Congo hemorrhagic fever virus strains circulating in Iran and Turkey: possibilities for transborder transmission. (22925023)
2012
26
Bradycardia in a patient with Crimean-Congo hemorrhagic fever related to ribavirin treatment. (23135017)
2012
27
Pediatric cases of Crimean-Congo hemorrhagic fever in Turkey. (22192531)
2012
28
Species distribution and detection of Crimean Congo Hemorrhagic Fever Virus (CCHFV) in field-collected ticks in Ankara Province, Central Anatolia, Turkey. (21910017)
2012
29
Crimean-Congo hemorrhagic fever virus in ticks, Southwestern Europe, 2010. (22261502)
2012
30
Effect of oral ribavirin treatment on the viral load and disease progression in Crimean-Congo hemorrhagic fever. (21106428)
2011
31
Species diversity of ixodid ticks feeding on humans in Amasya, Turkey: seasonal abundance and presence of Crimean-Congo hemorrhagic fever virus. (21337953)
2011
32
Crimean-Congo hemorrhagic fever in Europe: current situation calls for preparedness. (20403306)
2010
33
Evaluation of the association of serum levels of hyaluronic acid, sICAM-1, sVCAM-1, and VEGF-A with mortality and prognosis in patients with Crimean-Congo hemorrhagic fever. (20005156)
2010
34
Crimean-Congo hemorrhagic fever in Iran and neighboring countries. (20006541)
2010
35
Geographical distribution and surveillance of Crimean-Congo hemorrhagic fever in Iran. (20854025)
2010
36
Ancient common ancestry of Crimean-Congo hemorrhagic fever virus. (20074652)
2010
37
Towards an understanding of the migration of Crimean-Congo hemorrhagic fever virus. (19812264)
2010
38
Evaluation of the efficacy of ribavirin therapy on survival of Crimean-Congo hemorrhagic fever patients: a case-control study. (19168952)
2009
39
A case of Crimean-congo hemorrhagic fever with pleural effusion. (19168966)
2009
40
Crimean-Congo hemorrhagic fever. (17762783)
2007
41
A variable region in the Crimean-Congo hemorrhagic fever virus L segment distinguishes between strains isolated from different geographic regions. (16372290)
2006
42
Crimean-Congo hemorrhagic fever in Southeast of Iran. (16182370)
2006
43
Recombinant nucleoprotein-based serological diagnosis of Crimean-Congo hemorrhagic fever virus infections. (15602720)
2005
44
Sequence determination of the Crimean-Congo hemorrhagic fever virus L segment. (15033561)
2004
45
Crimean-Congo hemorrhagic fever virus glycoprotein proteolytic processing by subtilase SKI-1. (12885882)
2003
46
Treatment and prophylaxis with ribavirin for Crimean-Congo Hemorrhagic Fever--is it effective? (12666854)
2003
47
Isolation of Crimean-Congo hemorrhagic fever virus from ticks on imported Sudanese sheep in Saudi Arabia. (17322717)
2000
48
Replication and tissue tropisms of Crimean-Congo hemorrhagic fever virus in experimentally infected adult Hyalomma truncatum (Acari: Ixodidae). (1404255)
1992
49
Distribution of Crimean-Congo hemorrhagic fever viral antibody in Senegal: environmental and vectorial correlates. (2122750)
1990
50
Comparison of methods for isolation and titration of Crimean-Congo hemorrhagic fever virus. (3095367)
1986

Variations for Crimean-Congo Hemorrhagic Fever

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Expression for genes affiliated with Crimean-Congo Hemorrhagic Fever

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Search GEO for disease gene expression data for Crimean-Congo Hemorrhagic Fever.

Pathways for genes affiliated with Crimean-Congo Hemorrhagic Fever

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Pathways related to Crimean-Congo Hemorrhagic Fever according to GeneCards Suite gene sharing:

(show all 44)
idSuper pathwaysScoreTop Affiliating Genes
19.7IL6, TNF
29.7IL6, TNF
39.6NFKB1, TNF
49.6NFKB1, TNF
59.5IL6, NFKB1
69.5CASP3, TNF
7
Show member pathways
9.3IL6, TLR8, TNF
89.3CXCL10, IL6, TNF
9
Show member pathways
9.2IL6, NFKB1, TNF
109.2IL6, NFKB1, TNF
11
Show member pathways
9.2IL6, NFKB1, TNF
129.2IL6, NFKB1, TNF
139.2IL6, NFKB1, TNF
149.2IL6, NFKB1, TNF
15
Show member pathways
9.0CASP3, NFKB1, TNF
16
Show member pathways
9.0CASP3, NFKB1, TNF
178.9CASP3, IL6, NFKB1
188.9IL6, TNF, VEGFA
19
Show member pathways
8.8IL6, NFKB1, TLR8, TNF
208.8CXCL10, NFKB1, TLR8, TNF
21
Show member pathways
8.7CXCL10, IL6, NFKB1, TNF
228.7IL6, NFKB1, VEGFA
238.7CASP3, TNF, VEGFA
248.6CASP3, CXCL10, IL6, TNF
25
Show member pathways
8.6CASP3, IL6, NFKB1, TNF
268.6CASP3, IL6, NFKB1, TNF
278.6CASP3, IL6, NFKB1, TNF
288.6CASP3, IL6, NFKB1, TNF
298.6CASP3, IL6, NFKB1, TNF
308.5CASP3, NFKB1, VEGFA
31
Show member pathways
8.5F3, IL6, NFKB1, TLR8, TNF
32
Show member pathways
8.4CXCL10, IL6, NFKB1, TLR8, TNF
338.2CASP3, NFKB1, TNF, VEGFA
34
Show member pathways
8.1CASP3, CXCL10, IL6, NFKB1, TNF
35
Show member pathways
8.1CASP3, CXCL10, IL6, NFKB1, TNF
368.1CASP3, CXCL10, IL6, NFKB1, TNF
378.1CASP3, IL6, NFKB1, VEGFA
38
Show member pathways
7.8CASP3, NFKB1, TLR8, TNF, VEGFA
397.8CASP3, IL6, NFKB1, TNF, VEGFA
40
Show member pathways
7.7CASP3, CXCL10, IL6, NFKB1, TLR8, TNF
41
Show member pathways
7.7CASP3, CXCL10, IL6, NFKB1, TLR8, TNF
427.4CASP3, F3, IL6, NFKB1, TNF, VEGFA
437.4CASP3, IL6, NFKB1, TLR8, TNF, VEGFA
44
Show member pathways
7.3CASP3, CXCL10, IL6, NFKB1, TNF, VEGFA

GO Terms for genes affiliated with Crimean-Congo Hemorrhagic Fever

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Cellular components related to Crimean-Congo Hemorrhagic Fever according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.3CXCL10, IL6, TNF
2extracellular spaceGO:00056157.6CXCL10, F3, GPT, IL6, TNF, VEGFA

Biological processes related to Crimean-Congo Hemorrhagic Fever according to GeneCards Suite gene sharing:

(show all 25)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of interleukin-8 biosynthetic processGO:004541610.4TLR8, TNF
2positive regulation of chemokine productionGO:003272210.4IL6, TNF
3epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.4IL6, TNF
4negative regulation of lipid storageGO:001088810.3IL6, TNF
5cellular response to nicotineGO:007131610.3NFKB1, TNF
6response to auditory stimulusGO:001099610.2CXCL10, IL6
7positive regulation of positive chemotaxisGO:005092710.0F3, VEGFA
8positive regulation of protein kinase B signalingGO:00518979.9F3, IL6, TNF
9negative regulation of myoblast differentiationGO:00456629.9CXCL10, TNF
10positive regulation of protein complex assemblyGO:00313349.9TNF, VEGFA
11response to antibioticGO:00466779.9CASP3, IL6
12I-kappaB kinase/NF-kappaB signalingGO:00072499.8NFKB1, TLR8, TNF
13response to virusGO:00096159.7CXCL10, TLR8, TNF
14response to glucocorticoidGO:00513849.7CASP3, IL6, TNF
15positive regulation of NF-kappaB transcription factor activityGO:00510929.7IL6, NFKB1, TNF
16defense response to virusGO:00516079.5CXCL10, IL6, TLR8
17activation of cysteine-type endopeptidase activity involved in apoptotic processGO:00069199.4CASP3, F3, TNF
18regulation of cell proliferationGO:00421279.3CXCL10, IL6, TNF
19cellular response to lipopolysaccharideGO:00712229.2CXCL10, IL6, NFKB1, TNF
20response to lipopolysaccharideGO:00324969.1CASP3, CXCL10, F3, IL6
21positive regulation of peptidyl-serine phosphorylationGO:00331389.0IL6, TNF, VEGFA
22positive regulation of cell migrationGO:00303358.8CXCL10, F3, VEGFA
23inflammatory responseGO:00069548.7CXCL10, IL6, NFKB1, TLR8, TNF
24negative regulation of apoptotic processGO:00430668.2CASP3, IL6, NFKB1, VEGFA
25positive regulation of transcription from RNA polymerase II promoterGO:00459447.9CXCL10, IL6, NFKB1, TNF, VEGFA

Molecular functions related to Crimean-Congo Hemorrhagic Fever according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:00020209.2CASP3, F3, TNF
2cytokine activityGO:00051258.8IL6, TNF, VEGFA

Sources for Crimean-Congo Hemorrhagic Fever

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet