Crimean-Congo Hemorrhagic Fever (CCHF) malady

Disease Ontology:⁸ A viral infectious disease that is a hemorrhagic fever, has material basis in crimean-congo hemorrhagic fever virus, which is transmitted by hyalomma ticks. the infection has symptom headache, has symptom high fever, has symptom back pain, has symptom joint pain, has symptom stomach pain, has symptom vomiting, has symptom red eyes, has symptom flushed face, has symptom red throat, has symptom petechiae (red spots) on the palate, has symptom jaundice, has symptom nosebleeds, and has symptom blood in the feces and urine.

MalaCards: Crimean-Congo Hemorrhagic Fever, also known as crimean hemorrhagic fever, is related to encephalitis and cholecystitis, and has symptoms including joint pain, vomiting and jaundice. An important gene associated with Crimean-Congo Hemorrhagic Fever is CHIT1 (chitinase 1 (chitotriosidase)), and among its related pathways are Leishmaniasis and Legionellosis. The compounds cycloheximide and prednisolone have been mentioned in the context of this disorder. Affiliated tissues include eye, liver and testes, and related mouse phenotypes are respiratory system and muscle.

CDC:³ Crimean-Congo hemorrhagic fever (CCHF) is caused by infection with a tick-borne virus (Nairovirus) in the family Bunyaviridae. The disease was first characterized in the Crimea in 1944 and given the name Crimean hemorrhagic fever. It was then later recognized in 1969 as the cause of illness in the Congo, thus resulting in the current name of the disease.

External Ids:

Disease Ontology8 DOID:12287 MeSH34 D006479 NCIt39 C34682 ICD9CM27 065.0 SNOMED-CT56 43489008

ICD10 via Orphanet26 A98.0 SNOMED-CT via Orphanet57 43489008 ICD1025 A98.0 UMLS60 C0019099

Symptoms:

⁸ (show all 37)

joint pain vomiting jaundice headache liver/hepatic steatosis leukopenia/hypoleukocytosis nosebleeds back pain stomach pain red eyes high fever flushed face red throat petechiae (red spots) on the palate blood in the feces acute diarrhea chronic uveitis/blepharitis/episcleritis/scleritis/conjonctivitis/keratitis cough thoracic/chest pain

cutaneous rash hepatitis/icterus/cholestasis fever/chilling asthenia/fatigue/weakness early death/lethality collapse/sudden death/cardiac arrest/cardiorespiratory arrest myalgia/muscular pain acute abdominal pain/colic gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia hemorrhage/hemorrhagic syndrome/excessive/long-lasting bleeding epistaxis/nose bleeding pharyngitis abnormal hepatic enzymes/transaminases purpura/petichiae facial pain/cephalalgia/migraine thrombocytopenia/thrombopenia gingivorrhagia/gingival bleeding nausea/vomiting/regurgitation/merycism/hyperemesis

Search GEO for disease gene expression data for Crimean-Congo Hemorrhagic Fever.