CROUP
MCID: CRP002
MIFTS: 34

Croup (CROUP) malady

Respiratory diseases category

Summaries for Croup

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A respiratory system infectious disease that involves inflammation, edema, and subsequent obstruction of the larynx, trachea, and bronchi. the disease is caused by viruses, bacteria, allergies and inhaled irritants. it is marked by episodes of difficult breathing and hoarse metallic cough in infants and young children. croup is caused by parainfluenza virus (types 1 and 2), influenza a and b viruses, measles virus, adenovirus, respiratory syncytial virus, staphylococcus and streptococcus.

MalaCards: Croup, also known as laryngotracheobronchitis, is related to epiglottitis and laryngitis. An important gene associated with Croup is IYD (iodotyrosine deiodinase). Affiliated tissues include trachea, kidney and testes.

Wikipedia:63 Croup (or laryngotracheobronchitis) is a respiratory condition that is usually triggered by an acute... more...

Aliases & Classifications for Croup

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 34MeSH, 39NCIt, 56SNOMED-CT, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


Aliases & Descriptions:

croup 8 10 60
laryngotracheobronchitis 8 60
acute laryngotracheobronchitis 8
acute obstructive laryngitis 8
croup syndrome 8


External Ids:

Disease Ontology8 DOID:9395
MeSH34 D003440
NCIt39 C26735
ICD9CM27 464.4
ICD1025 J05.0

Related Diseases for Croup

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Croup via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 27)
idRelated DiseaseScoreTop Affiliating Genes
1epiglottitis10.7
2laryngitis10.4
3tracheitis10.4
4bronchiolitis10.4
5laryngotracheitis10.4
6asthma10.3
7bronchitis10.2
8influenza10.2
9pneumonia10.2
10pulmonary edema10.2
11acute laryngitis10.1
12arthritis10.1
13herpes simplex10.1
14myocarditis10.1
15cystic fibrosis9.9
16pharyngitis9.9
17viral pneumonia9.9
18cleft lip9.9
19cleft palate9.9
20gastroesophageal reflux disease9.9
21toxic shock syndrome9.9
22acute myocarditis9.9
23candidiasis9.9
24conjunctivitis9.9
25esophagitis9.9
26otitis media9.9
27psychosexual disorder9.9

Graphical network of the top 20 diseases related to Croup:



Diseases related to croup

Clinical Features for Croup

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Drugs & Therapeutics for Croup

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Croup

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Anatomical Context for Croup

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Sources:
32MalaCards
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MalaCards organs/tissues related to Croup:

32
Trachea, Kidney, Testes, Tongue

Animal Models for Croup or affiliated genes

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Publications for Croup

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Sources:
50PubMed
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Articles related to Croup:

(show top 50)    (show all 494)
idTitleAuthorsYear
1
Viral etiologies of infant bronchiolitis, croup and upper respiratory illness during 4 consecutive years. (23694832)
2013
2
The administration of general anesthesia to a patient with croup. (22435283)
2011
3
Seasonality patterns in croup presentations to emergency departments in Alberta, Canada: a time series analysis. (21490537)
2011
4
Response: cricoarytenoid arthritis presenting as croup. (20118331)
2010
5
Acute bronchiolitis and croup. (19135584)
2009
6
Croup. (19445760)
2009
7
Respiratory viruses in laryngeal croup of young children. (18410770)
2008
8
Epiglottitis and croup. (18435998)
2008
9
Correlating the clinical course of recurrent croup with endoscopic findings: a retrospective observational study. (18646444)
2008
10
Humidified air for croup? (17225704)
2007
11
Resuscitation great. Joseph O'Dwyer and laryngeal intubation for croup. (17382453)
2007
12
Humidified air inhalation for treating croup. (16855994)
2006
13
Differentiating stridor in children at triage: it's not always croup. (16198742)
2005
14
Current pharmacological options in the treatment of croup. (15757421)
2005
15
Corticosteroid treatment for acute croup. (12192364)
2002
16
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Nebulised epinephrine or corticosteroids in croup. (11300185)
2001
17
Effectiveness of glucocorticoids in treating croup. Authors acknowledge Cochrane Collaboration. (10591737)
1999
18
Effectiveness of glucocorticoids in treating croup. Children with croup should receive corticosteroids in primary care: results of audit. (10651482)
1999
19
Correction: The Treatment of Croup with Glucocorticoids. (9780347)
1998
20
Management of childhood croup. (9371203)
1997
21
Efficacy of oral dexamethasone for outpatient croup. (8917136)
1996
22
Sixteen years of croup in a Western Australian teaching hospital: effects of routine steroid treatment. (8953950)
1996
23
Treating croup with dexamethasone. (8606297)
1996
24
Use of racemic epinephrine, dexamethasone, and mist in the outpatient management of croup. (8806135)
1996
25
Inhalation of racemic adrenaline in the treatment of mild and moderately severe croup. Clinical symptom score and oxygen saturation measurements for evaluation of treatment effects. (7841729)
1994
26
Home management of the child with viral croup (laryngotracheobronchitis). (2031782)
1991
27
Croup in older children. Case report of 2 school-age children with croup. (2253432)
1990
28
A child with nocturnal croup. (2594677)
1989
29
Corticosteroids in croup: a chink in the ivory tower? (2754553)
1989
30
Recurrent and non-recurrent croup: an epidemiological study. (3266553)
1988
31
Croup syndrome: historical perspective. (3064041)
1988
32
Croup and cystic fibrosis. (3830010)
1987
33
The relationship of respiratory allergies to croup. (3745106)
1986
34
Humidification in viral croup: a controlled trial. (6397182)
1984
35
Spasmodic croup in the adult. (6340571)
1983
36
Rapid relief from croup. (21286035)
1982
37
Efficacy of helium--oxygen mixtures in the management of severe viral and post-intubation croup. (466564)
1979
38
Membranous laryngotracheobronchitis (membranous croup). (110070)
1979
39
Airway intervention in croup and epiglottitis: the changing role of the otolaryngologist. (112547)
1978
40
Pulmonary edema associated with croup and epiglottitis. (857236)
1977
41
Airway management in croup and epiglottitis. (349884)
1977
42
Croup: review and guidelines for management. (1089703)
1975
43
Letter: Racemic epinephrine in croup. (4812020)
1974
44
Letter: Management of croup. (4768926)
1973
45
Corticosteroids and croup: comments from a grass rooted ivory tower. (5059544)
1972
46
Corticosteroids in croup: reply from ground level. (5059305)
1972
47
Croup 1967-1969: survey from Wellington Hospital. (5289741)
1971
48
An outbreak of parainfluenza 2 (croup-associated) virus infection. Association with acute undifferentiated febrile illness in children. (13962308)
1963
49
Myocarditis and croup caused by Coxsackie virus type B5. (13863623)
1961
50
Croup and its management. (13700695)
1961

Genetic Variations for Croup

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Expression for genes affiliated with Croup

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Croup

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Pathways for genes affiliated with Croup

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Compounds for genes affiliated with Croup

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GO Terms for genes affiliated with Croup

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Products for genes affiliated with Croup

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  • Lysates
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Sources for Croup

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet