CROUP
MCID: CRP002
MIFTS: 33

Croup (CROUP) malady

Respiratory category

Summaries for Croup

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 A respiratory system infectious disease that involves inflammation, edema, and subsequent obstruction of the larynx, trachea, and bronchi. the disease is caused by viruses, bacteria, allergies and inhaled irritants. it is marked by episodes of difficult breathing and hoarse metallic cough in infants and young children. croup is caused by parainfluenza virus (types 1 and 2), influenza a and b viruses, measles virus, adenovirus, respiratory syncytial virus, staphylococcus and streptococcus.

MalaCards: Croup, also known as laryngotracheobronchitis, is related to epiglottitis and tracheitis. An important gene associated with Croup is IYD (iodotyrosine deiodinase). Affiliated tissues include tongue, kidney and b cells.

Wikipedia:64 Croup (or laryngotracheobronchitis) is a respiratory condition that is usually triggered by an acute... more...

Aliases & Classifications for Croup

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 35MeSH, 40NCIt, 57SNOMED-CT, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory


Aliases & Descriptions:

croup 8 10 61
laryngotracheobronchitis 8 61
acute laryngotracheobronchitis 8
acute obstructive laryngitis 8
croup syndrome 8


External Ids:

Disease Ontology8 DOID:9395
MeSH35 D003440
NCIt40 C26735
ICD9CM27 464.4
ICD1025 J05.0

Related Diseases for Croup

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Croup via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 23)
idRelated DiseaseScoreTop Affiliating Genes
1epiglottitis10.7
2tracheitis10.4
3bronchiolitis10.4
4laryngotracheitis10.4
5asthma10.4
6bronchitis10.2
7pulmonary edema10.2
8atopy10.2
9n syndrome10.1
10acute laryngitis10.1
11arthritis10.1
12pulmonary function10.1
13cystic fibrosis9.9
14trachoma9.9
15pharyngitis9.9
16viral pneumonia9.9
17cleft palate9.9
18gastroesophageal reflux disease9.9
19toxic shock syndrome9.9
20acute myocarditis9.9
21laryngomalacia9.9
22guillain-barr� syndrome9.9
23pulmonary disease, chronic obstructive9.9

Graphical network of the top 20 diseases related to Croup:



Diseases related to croup

Clinical Features for Croup

Drugs & Therapeutics for Croup

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Croup

Drug clinical trials:

Search ClinicalTrials for Croup

Search NIH Clinical Center for Croup

Search CenterWatch for Croup

Genetic Tests for Croup

Anatomical Context for Croup

Sources:
33MalaCards
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MalaCards organs/tissues related to Croup:

33
Tongue, Kidney, B cells, Trachea

Animal Models for Croup or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Croup

Sources:
51PubMed
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Articles related to Croup:

(show top 50)    (show all 495)
idTitleAuthorsYear
1
Nebulized epinephrine for croup in children. (24114291)
2013
2
Heliox in children with croup: a strategy to hasten improvement. (22541348)
2012
3
WITHDRAWN: Humidified air inhalation for treating croup. (21678339)
2011
4
Clinical inquiries. What's best for croup? (22049352)
2011
5
Croup. (20690441)
2010
6
A 4-year-old boy presenting with recurrent croup. (19859734)
2010
7
Should the recommended dose of epinephrine for severe croup be changed? (19097727)
2010
8
Croup. (18411388)
2008
9
Recurrent croup presentation, diagnosis, and management. (17980773)
2007
10
Oral or inhaled corticosteroids for the treatment of croup? (17430845)
2007
11
Croup in the paediatric emergency department. (19030411)
2007
12
100% humidity no better than blow-by for croup. (16795940)
2006
13
Controlled delivery of high vs low humidity vs mist therapy for croup in emergency departments: a randomized controlled trial. (16537737)
2006
14
Humidified air appears to be of no benefit in treating moderate croup. (17243307)
2006
15
Information from your family doctor. What should I know about croup? (14971836)
2004
16
Intramuscular versus oral dexamethasone for the treatment of moderate-to-severe croup: a randomized, double-blind trial. (12511310)
2003
17
Croup. (12603886)
2002
18
A randomized controlled trial of mist in the acute treatment of moderate croup. (12208675)
2002
19
An update on inflammatory disorders of the pediatric airway: epiglottitis, croup, and tracheitis. (11464324)
2001
20
Diagnosis of recurrent intermittent airway obstruction ("recurrent croup") in children. (11465816)
2001
21
Just the croup. (11272950)
2001
22
Role of glucocorticoids in treating croup. (11340753)
2001
23
Heliox treatment of severe croup. (11043633)
2000
24
Airway obstruction in pediatric patients. From croup to BOOP. (9465874)
1998
25
Treatment of croup with glucocorticoids. (9762386)
1998
26
Croup. (9348966)
1997
27
Steroids for intubated croup masking airway haemangioma. (8660054)
1996
28
Single dose of oral dexamethasone for outpatient croup. Failure to follow up all patients is a concern. (8898615)
1996
29
Outpatient treatment of croup with nebulized dexamethasone. (8634728)
1996
30
Hospitalized croup (bacterial and viral): the role of rigid endoscopy. (1564750)
1992
31
Steroids and croup. (2572852)
1989
32
A randomized double-blind, placebo-controlled trial of dexamethasone and racemic epinephrine in the treatment of croup. (3285638)
1988
33
Defective regulation of immune responses in croup due to parainfluenza virus. (2991841)
1985
34
Corticosteroid treatment of laryngotracheitis v spasmodic croup in children. (6688500)
1983
35
Lateral inspiration and expiration radiographs of the neck in children with laryngotracheitis (croup). (7134437)
1982
36
Radiographic tracheal diameter measurements in acute infectious croup: an objective scoring system. (7021067)
1981
37
Controversies in the management of supraglottitis and croup. (537855)
1979
38
Current management of croup and epiglottitis. (492795)
1979
39
The treatment of croup: continued controversy due to failure of recognition of historic, ecologic, etiologic and clinical perspectives. (762649)
1979
40
Airway intervention in croup and epiglottitis--update '78. (702103)
1978
41
General and family practice-epitomes of progress: treatment of croup. (18748103)
1977
42
Rapid diagnosis by immunofluorescence of viral infections associated with the croup syndrome in children. (4364234)
1974
43
Antibiotic usage in the management of acute laryngotracheobronchitis (croup). (4434666)
1974
44
Incidence and etiology of pneumonia, croup and bronchiolitis in preschool children belonging to a prepaid medical care group over a four-year period. (4347510)
1973
45
The diagnosis of epiglottitis: simplicity and reliability of radiographs of the neck in the differential diagnosis of the croup syndrome. (5016357)
1972
46
Spasmodic croup in children. Personal experiences with intermittent positive pressure breathing in therapy. (4563465)
1972
47
Corticosteroids in croup: Is there a reply from the ivory tower? (5094358)
1971
48
Management of croup. (6045908)
1967
49
Cortisone and phenylbutazone in the treatment of diphtheritic croup and non-diphtheritic stenosing laryngitis. (13751727)
1960
50
Croup viruses: clinical aspects. (13700696)
1960

Genetic Variations for Croup

Expression for genes affiliated with Croup

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Croup

Search GEO for disease gene expression data for Croup.

Pathways for genes affiliated with Croup

Compounds for genes affiliated with Croup

GO Terms for genes affiliated with Croup

Products for genes affiliated with Croup

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Sources for Croup

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet