CROUP
MCID: CRP002
MIFTS: 34

Croup (CROUP) malady

Respiratory diseases category

Summaries for Croup

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A respiratory system infectious disease that involves inflammation, edema, and subsequent obstruction of the larynx, trachea, and bronchi. the disease is caused by viruses, bacteria, allergies and inhaled irritants. it is marked by episodes of difficult breathing and hoarse metallic cough in infants and young children. croup is caused by parainfluenza virus (types 1 and 2), influenza a and b viruses, measles virus, adenovirus, respiratory syncytial virus, staphylococcus and streptococcus.

MalaCards: Croup, also known as laryngotracheobronchitis, is related to epiglottitis and laryngitis. An important gene associated with Croup is IYD (iodotyrosine deiodinase). Affiliated tissues include trachea, testes and tongue.

Wikipedia:63 Croup (or laryngotracheobronchitis) is a respiratory condition that is usually triggered by an acute... more...

Aliases & Classifications for Croup

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Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 34MeSH, 39NCIt, 56SNOMED-CT, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


Aliases & Descriptions:

croup 8 10 60
laryngotracheobronchitis 8 60
acute laryngotracheobronchitis 8
acute obstructive laryngitis 8
croup syndrome 8


External Ids:

Disease Ontology8 DOID:9395
MeSH34 D003440
NCIt39 C26735
ICD9CM27 464.4
ICD1025 J05.0

Related Diseases for Croup

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Croup via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 27)
idRelated DiseaseScoreTop Affiliating Genes
1epiglottitis10.7
2laryngitis10.4
3tracheitis10.4
4bronchiolitis10.4
5laryngotracheitis10.4
6asthma10.3
7bronchitis10.2
8influenza10.2
9pneumonia10.2
10pulmonary edema10.2
11acute laryngitis10.1
12arthritis10.1
13herpes simplex10.1
14myocarditis10.1
15cystic fibrosis9.9
16pharyngitis9.9
17viral pneumonia9.9
18cleft lip9.9
19cleft palate9.9
20gastroesophageal reflux disease9.9
21toxic shock syndrome9.9
22acute myocarditis9.9
23candidiasis9.9
24conjunctivitis9.9
25esophagitis9.9
26otitis media9.9
27psychosexual disorder9.9

Graphical network of the top 20 diseases related to Croup:



Diseases related to croup

Clinical Features for Croup

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Drugs & Therapeutics for Croup

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Croup

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Anatomical Context for Croup

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Sources:
32MalaCards
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MalaCards organs/tissues related to Croup:

32
Trachea, Testes, Tongue, Kidney

Animal Models for Croup or affiliated genes

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Publications for Croup

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Sources:
50PubMed
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Articles related to Croup:

(show top 50)    (show all 494)
idTitleAuthorsYear
1
Weather factors associated with paediatric croup presentations to an Australian emergency department. (23558151)
2014
2
A catastrophic presentation of adult croup. (23767911)
2013
3
Atypical croup: association with airway lesions, atopy, and esophagitis. (22588730)
2012
4
Evidence to support current use of nebulised epinephrine in croup to achieve immediate clinical improvement. (22417464)
2012
5
The effectiveness of local corticosteroids therapy in the management of mild to moderate viral croup. (20212395)
2010
6
Croup presentations to emergency departments in Alberta, Canada: a large population-based study. (19953656)
2010
7
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 4. Dose of dexamethasone in croup. (19307398)
2009
8
Risk factors for croup in children with recurrent respiratory infections: a case-control study. (19159401)
2009
9
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 1: Heliox in croup. (18499824)
2008
10
Bouchut, O'Dwyer and laryngeal intubation in patients with croup. (18320839)
2007
11
Comparison between single-dose oral prednisolone and oral dexamethasone in the treatment of croup: a randomized, double-blinded clinical trial. (17305661)
2007
12
Multiple pulmonary abscesses caused by Legionella pneumophila infection in an infant with croup. (16874182)
2006
13
Pulmonary arterial pressure in children with croup syndrome. (16647977)
2006
14
Nebulised L-epinephrine and steroid combination in the treatment of moderate to severe croup. (17523767)
2005
15
Croup--the bark is worse than the bite. (15385654)
2004
16
Oral dexamethasone for mild croup. (15619742)
2004
17
New approaches to respiratory infections in children. Bronchiolitis and croup. (11826639)
2002
18
Oral dexamethasone led to fewer treatment failures than did nebulized dexamethasone or placebo in children with mild croup. (12093230)
2002
19
A randomized comparison of helium-oxygen mixture (Heliox) and racemic epinephrine for the treatment of moderate to severe croup. (11389294)
2001
20
Viral croup. (11139641)
2001
21
Is oral dexamethasone as effective as intramuscular dexamethasone for outpatient management of moderate croup? (11252221)
2001
22
Croup and recurrent croup: their association with asthma and allergy. An epidemiological study on 5-8-year-old children. (10094451)
1999
23
Effectiveness of glucocorticoids in treating croup. General practitioners must be ready to treat children. (10651480)
1999
24
Nebulized budesonide and oral dexamethasone for treatment of croup: a randomized controlled trial. (9613912)
1998
25
Glucocorticoids in the treatment of croup: barking up the right tree. (9835881)
1998
26
Double blind placebo controlled trial of nebulised budesonide for croup. (9068309)
1997
27
Croup. (9052200)
1996
28
Outpatient management of croup. (8946123)
1996
29
Nebulized budesonide for children with mild-to-moderate croup. (8022437)
1994
30
Treatment of croup with nebulised steroid (budesonide): a double blind, placebo controlled study. (8466237)
1993
31
Dexamethasone for severe croup: what route? (8339167)
1993
32
Croup, epiglottitis, retropharyngeal abscess, and bacterial tracheitis: evolving patterns of occurrence and care. (1468809)
1992
33
Placebo-controlled trial of prednisolone in children intubated for croup. (1356176)
1992
34
Air pollution and pediatric respiratory disease: croup. (2117137)
1990
35
Mnemoniic for croup scoring. (2294157)
1990
36
Transcutaneous carbon dioxide pressure for monitoring patients with severe croup. (2121944)
1990
37
Management of croup. (2305724)
1990
38
Treatment of croup. A critical review. (2672782)
1989
39
The relationship between allergy and croup. (2670671)
1989
40
Croup and epiglottitis in children: the anesthesiologist as diagnostician. (3890618)
1985
41
Corticosteroid treatment of croup. (6731389)
1984
42
Airway reactivity in recurrent croup. (6578089)
1983
43
Croup: an 11-year study in a pediatric practice. (6304611)
1983
44
Efficacy of racemic epinephrine in croup. (6620031)
1983
45
Definition of croup. (7373480)
1980
46
Secondary airway support in the management of croup. (7452770)
1980
47
Comment on nasotracheal intubation and croup. (854382)
1977
48
Treatment of laryngotracheobronchitis (croup). Use of intermittent positive-pressure breathing and racemic epinephrine. (1096594)
1975
49
Corticosteroids in croup: is a controlled clinical trial needed? (5547886)
1971
50
INFLUENZA VIRUS B AS CAUSE OF ACUTE CROUP SYNDROME. (14067457)
1964

Genetic Variations for Croup

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Expression for genes affiliated with Croup

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Croup

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Pathways for genes affiliated with Croup

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Compounds for genes affiliated with Croup

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GO Terms for genes affiliated with Croup

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Products for genes affiliated with Croup

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Croup

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet