MCID: CRY006
MIFTS: 28

Cryofibrinogenemia

Categories: Rare diseases, Genetic diseases

Aliases & Classifications for Cryofibrinogenemia

MalaCards integrated aliases for Cryofibrinogenemia:

Name: Cryofibrinogenemia 49 69

Classifications:



External Ids:

UMLS 69 C0272263

Summaries for Cryofibrinogenemia

MalaCards based summary : Cryofibrinogenemia is related to cryoglobulinemia and purpura. An important gene associated with Cryofibrinogenemia is CD40LG (CD40 Ligand), and among its related pathways/superpathways are Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers and amb2 Integrin signaling. Affiliated tissues include skin, testes and b cells.

Wikipedia : 72 Cryofibrinogenemia refers to a condition classified as a fibrinogen disorder in which the chilling of an... more...

Related Diseases for Cryofibrinogenemia

Diseases in the Cryofibrinogenemia family:

Cryofibrinogenemia, Familial Primary

Diseases related to Cryofibrinogenemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 187)
# Related Disease Score Top Affiliating Genes
1 cryoglobulinemia 30.1 CD40LG CD79A
2 purpura 30.1 CD40LG CD79A
3 giardiasis 29.8 CD40LG CD79A
4 vasculitis 29.5 CD40LG CD79A
5 cryofibrinogenemia, familial primary 11.9
6 evans' syndrome 10.2 CD40LG HP
7 selective igg deficiency disease 10.2 CD40LG CD79A
8 c1q nephropathy 10.2 CD40LG CD79A
9 meningovascular neurosyphilis 10.2 CD40LG CD79A
10 alpha chain disease 10.2 CD40LG CD79A
11 brill-zinsser disease 10.2 CD40LG CD79A
12 exudative glomerulonephritis 10.2 CD40LG CD79A
13 cork-handlers' disease 10.2 CD40LG CD79A
14 salpingo-oophoritis 10.2 CD40LG CD79A
15 early yaws 10.1 CD40LG CD79A
16 ventilation pneumonitis 10.1 CD40LG CD79A
17 chronic interstitial cystitis 10.1 CD40LG CD79A
18 axillary adenitis 10.1 CD40LG CD79A
19 trichostrongyloidiasis 10.1 CD40LG CD79A
20 subacute bacterial endocarditis 10.1 CD40LG CD79A
21 heterophyiasis 10.1 CD40LG CD79A
22 immunoglobulin g deficiency 10.1 CD40LG CD79A
23 orbital granuloma 10.1 CD40LG CD79A
24 transient hypogammaglobulinemia of infancy 10.1 CD40LG CD79A
25 hyperglobulinemic purpura 10.1 CD40LG CD79A
26 gastroduodenitis 10.1 CD40LG CD79A
27 bacterial conjunctivitis 10.1 CD40LG CD79A
28 heavy chain disease 10.1 CD40LG CD79A
29 ophthalmia neonatorum 10.1 CD40LG CD79A
30 immunoglobulin a deficiency 1 10.1 CD40LG CD79A
31 dirofilariasis 10.1 CD40LG HP
32 parotid disease 10.1 CD40LG CD79A
33 cerebral arteritis 10.1 CD40LG CD79A
34 selective immunoglobulin deficiency disease 10.1 CD40LG CD79A
35 erythema elevatum diutinum 10.1 CD40LG CD79A
36 sporotrichosis 10.1 CD40LG CD79A
37 fallopian tube disease 10.1 CD40LG CD79A
38 hyperimmunoglobulin syndrome 10.1 CD40LG CD79A
39 congenital syphilis 10.1 CD40LG CD79A
40 polyclonal hypergammaglobulinemia 10.1 CD40LG CD79A
41 monoclonal paraproteinemia 10.1 CD40LG CD79A
42 salpingitis 10.1 CD40LG CD79A
43 ocular toxoplasmosis 10.1 CD40LG CD79A
44 parasitic ichthyosporea infectious disease 10.1 CD40LG CD79A
45 dysgammaglobulinemia 10.1 CD40LG CD79A
46 rheumatic fever 10.1 CD40LG HP
47 congenital hypogammaglobulinemia 10.1 CD40LG CD79A
48 acute maxillary sinusitis 10.1 CD40LG CD79A
49 rhinosporidiosis 10.1 CD40LG CD79A
50 chronic polyneuropathy 10.1 CD40LG CD79A

Graphical network of the top 20 diseases related to Cryofibrinogenemia:



Diseases related to Cryofibrinogenemia

Symptoms & Phenotypes for Cryofibrinogenemia

Drugs & Therapeutics for Cryofibrinogenemia

Search Clinical Trials , NIH Clinical Center for Cryofibrinogenemia

Genetic Tests for Cryofibrinogenemia

Anatomical Context for Cryofibrinogenemia

MalaCards organs/tissues related to Cryofibrinogenemia:

38
Skin, Testes, B Cells, Neutrophil, Kidney, Lung, Liver

Publications for Cryofibrinogenemia

Articles related to Cryofibrinogenemia:

(show top 50) (show all 64)
# Title Authors Year
1
Symptomatic Cryofibrinogenemia Following Trauma. ( 29189561 )
2017
2
Extensive auricular necroses as an initial symptom of cryofibrinogenemia occurring secondary to gastric diffuse large B-cell lymphoma. ( 28664978 )
2017
3
Cryofibrinogenemia-Induced Cutaneous Ulcers: A Review and Diagnostic Criteria. ( 27734332 )
2016
4
Cryofibrinogenemia: a marker of severity of cryoglobulinemia vasculitis. ( 25827358 )
2015
5
Cryofibrinogenemia and risk of cancer in cryoglobulinemic patients without vasculitis criteria. ( 26510517 )
2015
6
Cryofibrinogenemia associated with cryoglobulinemia--a severe case with amputation of four extremities. ( 25437275 )
2014
7
Cryofibrinogenemia After a Liver Transplant: First Reported Case Posttransplant and a Case-Based Review of the Nontransplant Literature. ( 24679054 )
2014
8
Cryofibrinogenemia triggered by a monoclonal paraprotein successfully treated with cyclophosphamide. ( 24356479 )
2014
9
Cryofibrinogenemia. ( 23519183 )
2013
10
Images in clinical medicine. Familial primary cryofibrinogenemia. ( 23964955 )
2013
11
Clinical significance of Cryofibrinogenemia: possible pathophysiological link with Raynaud's phenomenon. ( 22089468 )
2012
12
A 5-year prospective follow-up study in essential cryofibrinogenemia patients. ( 21549859 )
2011
13
Successful treatment of leg ulcer caused by cryofibrinogenemia by using a systemic corticosteroid and warfarin. ( 22098003 )
2011
14
Stanozolol treatment for successful prevention of attacks of severe primary cryofibrinogenemia. ( 20209649 )
2010
15
Healing of ulcers due to cryofibrinogenemia with colchicine and high-dose pentoxifylline. ( 19170411 )
2009
16
Cryofibrinogenemia: new insights into clinical and pathogenic features. ( 19958891 )
2009
17
Nephrotic syndrome and chronic renal insufficiency associated with essential cryofibrinogenemia. ( 17395660 )
2007
18
Cryofibrinogenemia associated with SjAPgren's syndrome: a case of successful treatment with high-dose corticosteroid. ( 17603248 )
2007
19
Cryofibrinogenemia associated with polyarteritis nodosa. ( 16292471 )
2006
20
Warfarin therapy for livedoid vasculopathy associated with cryofibrinogenemia and hyperhomocysteinemia. ( 16415390 )
2006
21
An approach to the diagnosis and treatment of cryofibrinogenemia. ( 14984819 )
2004
22
Nonhealing ulcer secondary to factor V Leiden mutation and cryofibrinogenemia. ( 15577768 )
2004
23
The histopathologic spectrum of cryofibrinogenemia in four anatomic sites. Skin, lung, muscle, and kidney. ( 12520706 )
2003
24
Cryofibrinogenemia due to Henoch-SchAPnlein purpura in a patient on peritoneal dialysis. ( 12691514 )
2003
25
Cryofibrinogenemia in a patient with B-cell lymphoma. ( 11707837 )
2000
26
Cryofibrinogenemia and skin necrosis in a patient with diffuse large cell lymphoma after high-dose chemotherapy and autologous stem cell transplantation. ( 11223976 )
2000
27
Familial primary cryofibrinogenemia. ( 10188150 )
1999
28
Central retinal vein occlusion associated with cryofibrinogenemia in a young adult--study of skin dynamic capillaroscopy. ( 9872035 )
1998
29
Cryofibrinogenemia: an addition to the differential diagnosis of calciphylaxis in end-stage renal disease. ( 9740168 )
1998
30
Cryofibrinogenemia with polyarthralgia, Raynaud's phenomenon and acral ulcer in a patient with Graves' disease treated with methimazole. ( 9213194 )
1997
31
Spontaneous necrosis of the skin associated with cryofibrinogenemia, cryoglobulinemia, and homocystinuria. ( 8879392 )
1996
32
Stanozolol causes rapid pain relief and healing of cutaneous ulcers caused by cryofibrinogenemia. ( 8425973 )
1993
33
A case of neutrophilic dermatosis (ND) complicated by cryofibrinogenemia (CFGN) and myelodysplastic syndrome (MDS). ( 1640024 )
1992
34
Cryofibrinogenemia: report of a case. ( 1679117 )
1991
35
Intravascular coagulation necrosis of the skin associated with cryofibrinogenemia, diabetes mellitus, and cardiolipin autoantibodies. ( 1761765 )
1991
36
Giardiasis, cryofibrinogenemia, and cold sensitivity: a response to metronidazole. ( 1938062 )
1991
37
Purpura and recurrent ulcers on the lower extremities. Essential cryofibrinogenemia. ( 1986695 )
1991
38
Thrombotic vasculopathy associated with cryofibrinogenemia. ( 1999545 )
1991
39
Thyrotoxicosis, cryofibrinogenemia, Sinutab Maximum Strength, and purple ears. ( 2930101 )
1989
40
First report case of cryoglobulinemia and cryofibrinogenemia in Thailand. ( 2809461 )
1989
41
Cutaneous lesions in cryofibrinogenemia. ( 6737150 )
1984
42
Factor XIII deficiency associated with Klippel-Weber disease, platelet dysfunction and cryofibrinogenemia. ( 6305083 )
1983
43
Cryofibrinogenemia in Henoch-SchAPnlein purpura: report of a case. ( 443956 )
1979
44
Testing for cryofibrinogenemia. ( 457999 )
1979
45
Testing for cryofibrinogenemia. ( 458000 )
1979
46
Cryofibrinogenemia, monoclonal gammopathy, and purpura. Report of a case and review of the literature. ( 426532 )
1979
47
Cryo corner: a complication of cryosurgery in a patient with cryofibrinogenemia. ( 151696 )
1978
48
Chronic ulcerative colitis, skin necrosis, and cryofibrinogenemia. ( 970774 )
1976
49
Serum levels of 2 -macroglobulin and IgG and cryofibrinogenemia in pregnancy. ( 4118750 )
1973
50
Anaphylactoid purpura, cold exposure, and cryofibrinogenemia. ( 4694049 )
1973

Variations for Cryofibrinogenemia

Expression for Cryofibrinogenemia

Search GEO for disease gene expression data for Cryofibrinogenemia.

Pathways for Cryofibrinogenemia

Pathways related to Cryofibrinogenemia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.24 CD79A FN1
2 10.84 FN1 HP
3 10.52 CD40LG CD79A
4 10.14 CD40LG FN1

GO Terms for Cryofibrinogenemia

Biological processes related to Cryofibrinogenemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell differentiation GO:0030183 9.16 CD40LG CD79A
2 acute-phase response GO:0006953 8.96 FN1 HP
3 B cell proliferation GO:0042100 8.62 CD40LG CD79A

Sources for Cryofibrinogenemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....