MCID: CRY005
MIFTS: 50

Cryptococcosis malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Cryptococcosis

Aliases & Descriptions for Cryptococcosis:

Name: Cryptococcosis 12 50 56 52 3 3 42 14
Infection by Cryptococcus Neoformans 69
Cryptococcus Neoformans Infection 12
Busse-Buschke's Disease 12
European Cryptococcosis 12
Cryptococcal Infection 12
Torulosis 12
Torula 12

Characteristics:

Orphanet epidemiological data:

56
cryptococcosis
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 56  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:12053
ICD10 33 B45 B45.9
ICD9CM 35 117.5
MeSH 42 D003453
NCIt 47 C2967
Orphanet 56 ORPHA1546
ICD10 via Orphanet 34 B45.1 B45.2 B45.3 more
MESH via Orphanet 43 D003453
UMLS 69 C0010414

Summaries for Cryptococcosis

CDC : 3 C. gattii infection is reportable in some states. Healthcare providers, please click here for more information about how to report cases.

MalaCards based summary : Cryptococcosis, also known as infection by cryptococcus neoformans, is related to cryptococcal meningitis and vitamin k deficiency hemorrhagic disease. An important gene associated with Cryptococcosis is SELL (Selectin L), and among its related pathways/superpathways are Innate Immune System and Toxoplasmosis. The drugs Amphotericin B and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include lung, liver and testes, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 An opportunistic mycosis that results_in fungal infection and has material basis in Cryptococcus neoformans or Cryptococcus gattii.

Wikipedia : 71 Cryptococcosis, also known as cryptococcal disease, is a potentially fatal fungal disease. It is caused... more...

Related Diseases for Cryptococcosis

Diseases related to Cryptococcosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 140)
id Related Disease Score Top Affiliating Genes
1 cryptococcal meningitis 11.2
2 vitamin k deficiency hemorrhagic disease 10.2 FCGR3A FCGR3B
3 recombinase activating gene 2 deficiency 10.2 FCGR3A FCGR3B
4 ectodermal dysplasia, anhidrotic, with t-cell immunodeficiency 10.2 FCGR3A FCGR3B
5 dental pulp necrosis 10.2 IFNG UNC119
6 hyperuricemia, pulmonary hypertension, renal failure, and alkalosis 10.1 FCGR2A MBL2 SELL
7 haemophilus meningitis 10.1 MBL2 TLR9
8 hereditary retinal dystrophy 10.1 FCGR3A FCGR3B
9 prostatic urethral cancer 10.1 IFNG SELL UNC119
10 cutaneous fibrous histiocytoma 10.1 FCGR3A IFNG
11 polyarteritis nodosa 10.1 IFNG TLR9
12 chronic gonorrhea of cervix 10.0 CARD9 IFNG MBL2
13 chorioretinitis 10.0 FCGR2A FCGR3A IFNG
14 neurotic disorder 10.0 FCGR2A FCGR3A FCGR3B IFNG
15 gonococcal synovitis 10.0 CD4 MBL2
16 endotheliitis 10.0
17 ciliary discoordination, due to random ciliary orientation 10.0 CD4 IFNG
18 tuberculosis 10.0
19 congestive heart failure 10.0 IFNG MBL2 SELL TLR9
20 total internal ophthalmoplegia 10.0 CD4 CLEC6A
21 angiolipoma 10.0 CD4 UNC119
22 pulmonary eosinophilia 10.0 FCGR2A IFNG MBL2 TLR9
23 meningitis 10.0
24 anterior foramen magnum meningioma 10.0 CD4 FCGR3A IFNG
25 asynchronous multifocal osteogenic sarcoma 10.0 CD4 FCGR3A FCGR3B
26 bulbospinal polio 9.9 CD4 FCGR3A FCGR3B
27 endometrial transitional cell carcinoma 9.9 IFNG MBL2 TLR9
28 extragonadal seminoma 9.9 CD4 FCGR2A FCGR3A
29 lung cancer 9.9
30 acquired immunodeficiency syndrome 9.9
31 cellulitis 9.9
32 arthritis 9.9
33 tularemia 9.9 CD4 IFNG TLR9
34 nonspecific interstitial pneumonia 9.9 CD4 IFNG TLR9
35 goodpasture syndrome 9.9 CD4 IFNG MBL2 SELL
36 multiple carboxylase deficiency 9.9 CD4 IFNG TLR9
37 lambda 5 deficiency 9.9 CARD9 CD4
38 foodborne botulism 9.9 CD4 IFNG TLR9
39 rheumatoid arthritis 9.9
40 waldeyer's ring cancer 9.9 CARD9 CD4
41 childhood malignant hemangiopericytoma 9.8 CD4 IFNG TLR9
42 exophthalmos 9.8 CD4 IFNG TLR9
43 lymphoma 9.8
44 molluscum contagiosum 9.8
45 elephantiasis 9.8 CD4 IFNG
46 mediastinitis 9.8
47 systemic lupus erythematosus 9.8
48 hepatitis 9.8
49 cerebritis 9.8
50 candidiasis 9.8

Comorbidity relations with Cryptococcosis via Phenotypic Disease Network (PDN):


Acute Cystitis Cryptococcal Meningitis
Deficiency Anemia

Graphical network of the top 20 diseases related to Cryptococcosis:



Diseases related to Cryptococcosis

Symptoms & Phenotypes for Cryptococcosis

MGI Mouse Phenotypes related to Cryptococcosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.61 CARD9 CD4 CLEC6A FCGR2A FCGR3B IFNG
2 immune system MP:0005387 9.28 CARD9 CD4 CLEC6A FCGR2A FCGR3B IFNG

Drugs & Therapeutics for Cryptococcosis

Drugs for Cryptococcosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 72)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amphotericin B Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 1397-89-3 14956 5280965
2
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
3
Fluconazole Approved Phase 4,Phase 3,Phase 2,Phase 1 86386-73-4 3365
4
Voriconazole Approved, Investigational Phase 4 137234-62-9 71616
5
Itraconazole Approved, Investigational Phase 4,Phase 3,Phase 2 84625-61-6 55283
6
Efavirenz Approved, Investigational Phase 4 154598-52-4 64139
7
Lamivudine Approved, Investigational Phase 4 134678-17-4 60825
8
Stavudine Approved, Investigational Phase 4 3056-17-5 18283
9
Zidovudine Approved Phase 4 30516-87-1 35370
10 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1,Phase 2
11 Antifungal Agents Phase 4,Phase 3,Phase 2,Phase 1
12 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
13 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Phase 1
14 Antiprotozoal Agents Phase 4,Phase 3,Phase 2,Phase 1
15 Liposomal amphotericin B Phase 4,Phase 3,Phase 1,Phase 2
16 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
17 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
18 Hormones Phase 4,Phase 3,Phase 2,Phase 1
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
20 Steroid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
21 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
22 Pharmaceutical Solutions Phase 4,Phase 3
23 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 3,Phase 2
24 Hydroxyitraconazole Phase 4,Phase 3,Phase 2
25 Anti-HIV Agents Phase 4
26 Anti-Retroviral Agents Phase 4
27 Antiviral Agents Phase 4,Phase 2
28 Cytochrome P-450 CYP3A Inducers Phase 4
29 Nucleic Acid Synthesis Inhibitors Phase 4
30 Reverse Transcriptase Inhibitors Phase 4
31
Flucytosine Approved Phase 2, Phase 3 2022-85-7 3366
32
Posaconazole Approved, Investigational, Vet_approved Phase 3,Phase 2 171228-49-2 147912
33
Clotrimazole Approved, Vet_approved Phase 3 23593-75-1 2812
34
Sertraline Approved Phase 3 79617-96-2 68617
35 Antimetabolites Phase 2, Phase 3
36 Antidepressive Agents Phase 3
37 Neurotransmitter Agents Phase 3
38 Neurotransmitter Uptake Inhibitors Phase 3
39 Psychotropic Drugs Phase 3
40
Serotonin Phase 3 50-67-9 5202
41 Serotonin Agents Phase 3
42 Serotonin Uptake Inhibitors Phase 3
43
deoxycholic acid Approved Phase 1, Phase 2 83-44-3 222528
44
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
45
Tamoxifen Approved Phase 2 10540-29-1 2733526
46 Amphotericin B, deoxycholate drug combination Phase 1, Phase 2
47 Gastrointestinal Agents Phase 2
48 Antiemetics Phase 2
49 Anti-Inflammatory Agents Phase 2
50 Antineoplastic Agents, Hormonal Phase 2

Interventional clinical trials:

(show top 50) (show all 55)
id Name Status NCT ID Phase
1 Safety, Efficacy, and Pharmacokinetics of Amphotericin B Lipid Complex Completed NCT01656382 Phase 4
2 A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal Infections Completed NCT00647907 Phase 4
3 Operational Research for Cryptococcal Antigen Screening Completed NCT01535469 Phase 4
4 Optimal Time to Start Antiretroviral Therapy in HIV-infected Adults With Cryptococcal Meningitis Completed NCT00976040 Phase 4
5 Efficacy of Itraconazole as Secondary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation or Chemotherapy With Prior Invasive Fungal Infection Completed NCT01198236 Phase 4
6 Cryptococcal Optimal ART Timing Trial Completed NCT01075152 Phase 4
7 Efficacy of Intrathecal Administration of Liposomal Amphotericin B in Cryptococcal Meningitis Not yet recruiting NCT02686853 Phase 4
8 Efficacy, Safety and Pharmacokinetics of SPK-843 in the Treatment of Pulmonary Mycosis Unknown status NCT01125644 Phase 3
9 Open Label Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P00041) Completed NCT00034658 Phase 3
10 Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081) Completed NCT00000676 Phase 3
11 Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P02095) Completed NCT00034632 Phase 3
12 A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection Completed NCT00784368 Phase 3
13 Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS Completed NCT00001017 Phase 3
14 Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC Completed NCT01589289 Phase 3
15 Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis Recruiting NCT01802385 Phase 3
16 Study Evaluating Efficiency and Tolerance of High-dose Fluconazole Associated With Flucytosine as Induction Therapy for Cryptococcal Meningitis Associated With HIV in Sub-saharan Africa Active, not recruiting NCT01715922 Phase 2, Phase 3
17 Cryptococcal Antigen Screening Plus Sertraline Not yet recruiting NCT03002012 Phase 3
18 PK/PD Study of Posaconazole for Empiric Treatment of Invasive Fungal Infections in Neutropenic Patients or Treatment of Refractory Invasive Fungal Infections (Study P01893) Completed NCT00034671 Phase 2
19 High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected Individuals Completed NCT00885703 Phase 1, Phase 2
20 Dexamethasone in Cryptococcal Meningitis Completed NCT00000776 Phase 2
21 Amphotericin Alone or in Combination With Fluconazole for AIDS-Associated Meningitis Completed NCT00145249 Phase 2
22 Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis Completed NCT00012467 Phase 2
23 Treatment With Tamoxifen in Cryptococcal Meningitis Not yet recruiting NCT03112031 Phase 2
24 Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS Terminated NCT00847678 Phase 2
25 Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS Terminated NCT00324025 Phase 2
26 SCH 39304 as Therapy for Acute Cryptococcal Meningitis in HIV-Infected Patients Followed by Maintenance Therapy Completed NCT00000677 Phase 1
27 The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis Completed NCT00002316 Phase 1
28 Vietnam Cryptococcal Retention in Care Study (CRICS) Federal Financial Report Recruiting NCT02955862 Phase 1
29 Vietnam Cryptococcal Retention in Care Study Unknown status NCT02334670
30 Liposomal Amphotericin B for the Treatment of Cryptococcal Meningitis Unknown status NCT02136030
31 Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Cryptococcus Neoformans Infection in Patients Not Infected With HIV and Complications Associated With Cryptococcus Neoformans Infection Completed NCT00001701
32 A Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal Meningitis Completed NCT00000639
33 A Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected Patients Completed NCT00002438
34 Nevirapine Levels and Fluconazole Completed NCT00309582
35 A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients With AIDS Completed NCT00002294
36 Multi-center Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis Completed NCT00000708
37 A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis. Completed NCT00002113
38 A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients Who Have Not Had Success With Amphotericin B Completed NCT00002306
39 Pilot Study of Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis Completed NCT00002076
40 Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Maintenance Treatment for the Prevention of Relapse of Cryptococcal Meningitis in Patients With Acquired Immunodeficiency Syndrome Completed NCT00002074
41 Safety and Efficacy of Amphotericin B Lipid Complex in the Treatment of Cryptococcal Meningitis in Patients With the Acquired Immunodeficiency Syndrome Completed NCT00002019
42 A Comparison of Fluconazole and Amphotericin B in the Treatment of Cryptococcal Meningitis Completed NCT00002305
43 Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis Completed NCT00002075
44 A Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis Completed NCT00002068
45 An Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis Completed NCT00002077
46 Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis Completed NCT00002040
47 Clinical Outcomes of Cryptococcal Meningitis Among HIV-infected Patients in the Era of Antiretroviral Therapy Completed NCT02098525
48 Early Versus Delayed Antiretroviral Therapy (ART) in the Treatment of Cryptococcal Meningitis in Africa Completed NCT00830856
49 Evaluation and Follow-up of Patients With Cryptococcosis Recruiting NCT00001352
50 Idiopathic CD4 Lymphocytopenia Recruiting NCT02113930

Search NIH Clinical Center for Cryptococcosis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: cryptococcosis

Genetic Tests for Cryptococcosis

Anatomical Context for Cryptococcosis

MalaCards organs/tissues related to Cryptococcosis:

39
Lung, Liver, Testes, T Cells, Bone, Kidney, Bone Marrow

Publications for Cryptococcosis

Articles related to Cryptococcosis:

(show top 50) (show all 639)
id Title Authors Year
1
Cryptococcosis in Patients with Nephrotic Syndrome: A Pooled Analysis of Cases. ( 28054218 )
2017
2
Cryptococcosis mimicking lung carcinoma with brain metastases in an immunocompetent patient. ( 27769644 )
2017
3
Disseminated Cryptococcosis in an Immunocompetent Child. ( 28044302 )
2017
4
First report of canine systemic cryptococcosis owing to Cryptococcus gattii in Europe. ( 27868198 )
2017
5
Disseminated cryptococcosis presenting as cellulitis. ( 27779149 )
2017
6
Paracoccidioidomycosis and cryptococcosis with localized skin manifestations: report of two cases in the elderly. ( 27192530 )
2016
7
Disseminated Cryptococcosis Due to Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies in the Absence of Pulmonary Alveolar Proteinosis. ( 28013480 )
2016
8
Common invasive fungal diseases: an overview of invasive candidiasis, aspergillosis, cryptococcosis, and Pneumocystis pneumonia. ( 26901377 )
2016
9
The CD4(+) T-lymphocyte count is an important predictor for the prognosis of cryptococcosis. ( 28035481 )
2016
10
Immune reconstitution inflammatory syndrome, with pulmonary and neurological cryptococcosis, in an HIV-negative patient. ( 28057973 )
2016
11
Cryptococcosis. ( 26897067 )
2016
12
Oral Cryptococcosis in a Patient with Chronic Lymphocytic Leukemia. ( 27425164 )
2016
13
Cases of disseminated cryptococcosis in intravenous drug abusers without HIV infection: A new risk factor? ( 27995054 )
2016
14
Cryptococcosis in anti-interferon-gamma autoantibodies-positive patients: a different clinical manifestation from HIV-infected patients. ( 27169938 )
2016
15
Cryptococcosis: The Ubiquitous Yeast. ( 27766796 )
2016
16
Equine Pulmonary Cryptococcosis: A Comparative Literature Review and Evaluation of Fluconazole Monotherapy. ( 27655152 )
2016
17
Cryptococcosis - The Impact of Delay to Diagnosis. ( 27172806 )
2016
18
The current treatment landscape: other fungal diseases (cryptococcosis, fusariosis and mucormycosis). ( 27880667 )
2016
19
Identification of Disseminated Cryptococcosis Using MALDI-TOF MS and Clinical Evaluation. ( 27581774 )
2016
20
Isavuconazole Treatment of Cryptococcosis and Dimorphic Mycoses. ( 27169478 )
2016
21
A case of cutaneous Rhodotorula infection mimicking cryptococcosis. ( 27790744 )
2016
22
Cryptococcosis in non-HIV/non-transplant patients: A Brazilian case series. ( 27118805 )
2016
23
Lung epithelium is the major source of IL-33 and is regulated by IL-33-dependent and IL-33-independent mechanisms in pulmonary cryptococcosis. ( 27596810 )
2016
24
Cytological diagnosis of biliary cryptococcosis in an immunocompromised patient with mid common bile duct stricture masquerading as cholangiocarcinoma. ( 27592857 )
2016
25
Clinical analysis of non-AIDS patients pathologically diagnosed with pulmonary cryptococcosis. ( 27867557 )
2016
26
Detection of cryptococcosis in liquid-based sputum cytology. ( 28008666 )
2016
27
Intestinal Lesion in a Dog Due to Cryptococcus gattii Type VGII and Review of Published Cases of Canine Gastrointestinal Cryptococcosis. ( 27988905 )
2016
28
Changing epidemiology of HIV-associated cryptococcosis in sub-Saharan Africa. ( 27477977 )
2016
29
Delayed Diagnosis of Disseminated Cryptococcosis with Associated Meningoencephalitis in an Immunocompetent Septuagenarian Host. ( 27566500 )
2016
30
Diabetes mellitus is associated with acquisition and increased mortality in HIV-uninfected patients with cryptococcosis: A population-based study. ( 26920792 )
2016
31
Clinical Diversity of CNS Cryptococcosis. ( 27766797 )
2016
32
Glucosylceramide Administration as a Vaccination Strategy in Mouse Models of Cryptococcosis. ( 27082428 )
2016
33
Primary cutaneous cryptococcosis during infliximab therapy. ( 27637071 )
2016
34
Unique characteristics of cryptococcosis identified after death in patients with liver cirrhosis: comparison with concurrent cohort diagnosed antemortem. ( 27601609 )
2016
35
Localized Cutaneous Cryptococcosis: Summary of Reported Cases in Japan. ( 27581773 )
2016
36
The celecoxib derivative AR-12 has broad spectrum antifungal activity in vitro and improves the activity of fluconazole in a murine model of cryptococcosis. ( 27645246 )
2016
37
Performance of the Cryptococcal Antigen Lateral Flow Assay in Non-HIV-Related Cryptococcosis. ( 26607986 )
2016
38
Cryptococcosis in Acquired Immunodeficiency Syndrome Patients Clinically Confirmed and/or Diagnosed at Necropsy in a Teaching Hospital in Brazil. ( 27458037 )
2016
39
Disseminated Cryptococcosis in a 63-year-old Patient with Multiple Sclerosis Treated with Fingolimod. ( 27853088 )
2016
40
End-Stage Liver Disease Is a Strong Predictor of Early Mortality in Cryptococcosis. ( 26835475 )
2016
41
Symptomless Pulmonary Cryptococcosis in a Psoriatic Arthritis Patient during Infliximab Therapy. ( 27081286 )
2016
42
Refractory and/or Relapsing Cryptococcosis Associated with Acquired Immune Deficiency Syndrome: Clinical Features, Genotype, and Virulence Factors of Cryptococcus spp. Isolates. ( 26928832 )
2016
43
Integrated therapy for HIV and cryptococcosis. ( 27906037 )
2016
44
Cryptococcosis and tuberculosis co-infection in mainland China. ( 27599473 )
2016
45
Pharmacokinetics/pharmacodynamic correlations of fluconazole in murine model of cryptococcosis. ( 27235581 )
2016
46
Disseminated cryptococcosis in an immunocompetent child. ( 27852678 )
2016
47
Adrenal cryptococcosis in an immunosuppressed patient showing intensely increased metabolic activity on (18)F-FDG PET/CT. ( 27473097 )
2016
48
A subdose of fluconazole alters the virulence of Cryptococcus gattii during murine cryptococcosis and modulates type I interferon expression. ( 27486215 )
2016
49
Disseminated cryptococcosis presenting as mediastinal and hilar lymphadenopathy in an immunocompetent patient. ( 27512567 )
2016
50
A case of pulmonary cryptococcosis with large pericardial effusion diagnosed using cervical lymph node biopsy. ( 27873481 )
2016

Variations for Cryptococcosis

Expression for Cryptococcosis

Search GEO for disease gene expression data for Cryptococcosis.

Pathways for Cryptococcosis

GO Terms for Cryptococcosis

Cellular components related to Cryptococcosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.81 CARD9 CD4 CLEC6A FCGR2A FCGR3A FCGR3B
2 secretory granule membrane GO:0030667 9.13 FCGR2A FCGR3B SELL
3 external side of plasma membrane GO:0009897 8.92 CD4 FCGR3A IFNG SELL

Biological processes related to Cryptococcosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 innate immune response GO:0045087 9.71 CARD9 CLEC6A MBL2 TLR9
2 immune response GO:0006955 9.67 CD4 FCGR3A FCGR3B IFNG
3 defense response to bacterium GO:0042742 9.65 IFNG MBL2 TLR9
4 regulation of immune response GO:0050776 9.63 FCGR3A IFNG SELL
5 adaptive immune response GO:0002250 9.61 CD4 CLEC6A IFNG
6 immune system process GO:0002376 9.55 CARD9 CD4 CLEC6A MBL2 TLR9
7 positive regulation of interleukin-12 production GO:0032735 9.32 IFNG TLR9
8 negative regulation of growth of symbiont in host GO:0044130 9.26 IFNG MBL2
9 positive regulation of tumor necrosis factor production GO:0032760 9.13 CARD9 IFNG TLR9
10 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 8.92 CARD9 CD4 CLEC6A TLR9

Molecular functions related to Cryptococcosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 carbohydrate binding GO:0030246 9.13 CLEC6A MBL2 SELL
2 IgG binding GO:0019864 8.8 FCGR2A FCGR3A FCGR3B

Sources for Cryptococcosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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