MCID: CRY005
MIFTS: 54

Cryptococcosis

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Cryptococcosis

MalaCards integrated aliases for Cryptococcosis:

Name: Cryptococcosis 12 72 49 55 51 3 3 41 14
Infection by Cryptococcus Neoformans 69
Cryptococcus Neoformans Infection 12
Busse-Buschke's Disease 12
European Cryptococcosis 12
Cryptococcal Infection 12
Torulosis 12
Torula 12

Characteristics:

Orphanet epidemiological data:

55
cryptococcosis
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 55  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:12053
ICD10 32 B45 B45.9
ICD9CM 34 117.5
MeSH 41 D003453
NCIt 46 C2967
Orphanet 55 ORPHA1546
MESH via Orphanet 42 D003453
UMLS via Orphanet 70 C0010414
ICD10 via Orphanet 33 B45.0 B45.1 B45.2 more
UMLS 69 C0010414

Summaries for Cryptococcosis

CDC : 3 C. gattii infection is reportable in some states. Healthcare providers, please click here for more information about how to report cases.

MalaCards based summary : Cryptococcosis, also known as infection by cryptococcus neoformans, is related to cryptococcal meningitis and meningitis. An important gene associated with Cryptococcosis is SELL (Selectin L), and among its related pathways/superpathways are Innate Immune System and NF-kappaB Signaling. The drugs Amphotericin B and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include lung, liver and testes, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Disease Ontology : 12 An opportunistic mycosis that results_in fungal infection and has material basis in Cryptococcus neoformans or Cryptococcus gattii.

Wikipedia : 72 Cryptococcosis, also known as cryptococcal disease, is a potentially fatal fungal disease. It is caused... more...

Related Diseases for Cryptococcosis

Diseases related to Cryptococcosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 195)
# Related Disease Score Top Affiliating Genes
1 cryptococcal meningitis 32.4 IFNG MBL2
2 meningitis 30.2 FCGR2A IFNG MBL2 TLR9
3 candidiasis 29.7 CARD9 IFNG PLB1
4 coccidioidomycosis 29.7 CARD9 MBL2
5 mycobacterium tuberculosis 1 29.5 IFNG IL4 MBL2 SELL TLR9
6 lymphopenia 29.4 IFNG SELL UNC119
7 aspergillosis 29.3 IFNG IL4 MBL2 TLR9
8 toxoplasmosis 29.1 IFNG IL4 TLR9
9 bronchiolitis 29.1 IFNG IL4 TLR9
10 pulmonary tuberculosis 29.0 IFNG IL4 MBL2 TLR9
11 leishmaniasis 29.0 IFNG IL4 TLR9
12 colitis 29.0 IFNG IL4 TLR9
13 systemic lupus erythematosus 28.3 FCGR2A FCGR3A FCGR3B IFNG IL4 MBL2
14 transient neonatal neutropenia 10.5 FCGR3A FCGR3B
15 spastic paraplegia 32, autosomal recessive 10.4 FCGR3A FCGR3B
16 rheumatic myocarditis 10.4 FCGR3A FCGR3B
17 adult dermatomyositis 10.4 MBL2 TLR9
18 orbital plasma cell granuloma 10.4 FCGR3A FCGR3B
19 adult lymphoma 10.4 FCGR2A FCGR3A
20 meningococcal meningitis 10.4 MBL2 TLR9
21 myositis fibrosa 10.4 IFNG TLR9
22 chronic orbital inflammation 10.3 FCGR3A FCGR3B
23 central nervous system vasculitis 10.3 IFNG TLR9
24 chronic nk-cell lymphocytosis 10.3 FCGR3A FCGR3B
25 neisseria meningitidis infection 10.3 FCGR2A MBL2
26 kawasaki disease 10.3 FCGR2A MBL2 SELL
27 invasive aspergillosis 10.3 IFNG MBL2 TLR9
28 diffuse infiltrative lymphocytosis syndrome 10.2 FCGR3A FCGR3B
29 fungal meningitis 10.2 IFNG UNC119
30 plasmodium falciparum malaria 10.2 FCGR2A IFNG TLR9
31 exanthema subitum 10.2 FCGR3A FCGR3B
32 mycoplasmal pneumonia 10.1 IFNG IL4
33 endotheliitis 10.1
34 hyperlucent lung 10.1 IFNG IL4
35 behcet syndrome 10.1 IFNG MBL2 SELL TLR9
36 b-cell growth factor 10.1 IFNG IL4
37 baylisascariasis 10.1 IFNG IL4
38 penicillin allergy 10.1 IFNG IL4
39 ovarian cystic teratoma 10.1 FCGR3A FCGR3B
40 atopic keratoconjunctivitis 10.1 IFNG IL4
41 hyper ige syndrome 10.0 IFNG IL4
42 orofacial granulomatosis 10.0 IFNG IL4
43 buruli ulcer 10.0 IFNG IL4
44 lung cancer 10.0
45 cellulitis 10.0
46 microscopic colitis 10.0 IFNG IL4
47 urinary schistosomiasis 10.0 IFNG IL4
48 arthritis 10.0
49 toxic oil syndrome 10.0 IFNG IL4
50 rheumatoid arthritis 10.0

Comorbidity relations with Cryptococcosis via Phenotypic Disease Network (PDN):


Acute Cystitis Cryptococcal Meningitis
Deficiency Anemia

Graphical network of the top 20 diseases related to Cryptococcosis:



Diseases related to Cryptococcosis

Symptoms & Phenotypes for Cryptococcosis

GenomeRNAi Phenotypes related to Cryptococcosis according to GeneCards Suite gene sharing:

25 (show all 17)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.64 IL4
2 Increased shRNA abundance (Z-score > 2) GR00366-A-107 9.64 MBL2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.64 MBL2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-118 9.64 CGB3
5 Increased shRNA abundance (Z-score > 2) GR00366-A-124 9.64 CARD9
6 Increased shRNA abundance (Z-score > 2) GR00366-A-138 9.64 CARD9
7 Increased shRNA abundance (Z-score > 2) GR00366-A-182 9.64 CARD9
8 Increased shRNA abundance (Z-score > 2) GR00366-A-185 9.64 IL4
9 Increased shRNA abundance (Z-score > 2) GR00366-A-202 9.64 MBL2
10 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.64 MBL2 CARD9
11 Increased shRNA abundance (Z-score > 2) GR00366-A-22 9.64 IL4
12 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.64 CARD9
13 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.64 CGB3
14 Increased shRNA abundance (Z-score > 2) GR00366-A-36 9.64 CARD9
15 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.64 IL4 MBL2 CARD9 CGB3
16 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.64 MBL2
17 Increased shRNA abundance (Z-score > 2) GR00366-A-70 9.64 IL4

MGI Mouse Phenotypes related to Cryptococcosis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.61 IL4 MBL2 SELL TLR9 CARD9 CLEC6A
2 immune system MP:0005387 9.28 IFNG IL4 MBL2 SELL TLR9 CARD9

Drugs & Therapeutics for Cryptococcosis

Drugs for Cryptococcosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 71)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amphotericin B Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 1397-89-3 5280965 14956
2
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
3
Fluconazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 86386-73-4 3365
4
Voriconazole Approved, Investigational Phase 4 137234-62-9 71616
5
Itraconazole Approved, Investigational Phase 4,Phase 3,Phase 2 84625-61-6 55283
6
Efavirenz Approved, Investigational Phase 4 154598-52-4 64139
7
Lamivudine Approved, Investigational Phase 4 134678-17-4 60825
8
Stavudine Approved, Investigational Phase 4 3056-17-5 18283
9
Zidovudine Approved Phase 4 30516-87-1 35370
10 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1,Phase 2
11 Antifungal Agents Phase 4,Phase 3,Phase 2,Phase 1
12 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
13 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Phase 1
14 Antiprotozoal Agents Phase 4,Phase 3,Phase 2,Phase 1
15 Liposomal amphotericin B Phase 4,Phase 3,Phase 1,Phase 2
16 Pharmaceutical Solutions Phase 4,Phase 3
17 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
18 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
19 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
20 Hormones Phase 4,Phase 3,Phase 2,Phase 1
21 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
22 Steroid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
23 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 3,Phase 2
24 Hydroxyitraconazole Phase 4,Phase 3,Phase 2
25 Anti-HIV Agents Phase 4
26 Anti-Retroviral Agents Phase 4
27 Antiviral Agents Phase 4,Phase 2
28 Cytochrome P-450 CYP3A Inducers Phase 4
29 Nucleic Acid Synthesis Inhibitors Phase 4
30 Reverse Transcriptase Inhibitors Phase 4
31
Flucytosine Approved, Investigational Phase 2, Phase 3 2022-85-7 3366
32
Posaconazole Approved, Investigational, Vet_approved Phase 3,Phase 2 171228-49-2 147912
33
Clotrimazole Approved, Vet_approved Phase 3 23593-75-1 2812
34
Sertraline Approved Phase 3 79617-96-2 68617
35 Antidepressive Agents Phase 3
36 Neurotransmitter Agents Phase 3
37 Neurotransmitter Uptake Inhibitors Phase 3
38 Psychotropic Drugs Phase 3
39
Serotonin Phase 3 50-67-9 5202
40 Serotonin Agents Phase 3
41 Serotonin Uptake Inhibitors Phase 3
42 Antimetabolites Phase 2, Phase 3
43
deoxycholic acid Approved Phase 1, Phase 2 83-44-3 222528
44
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
45
Tamoxifen Approved Phase 2 10540-29-1 2733526
46 Amphotericin B, deoxycholate drug combination Phase 1, Phase 2
47 Gastrointestinal Agents Phase 2
48 Antiemetics Phase 2
49 Anti-Inflammatory Agents Phase 2
50 Antineoplastic Agents, Hormonal Phase 2

Interventional clinical trials:

(show top 50) (show all 58)

# Name Status NCT ID Phase Drugs
1 Efficacy of Intrathecal Administration of Liposomal Amphotericin B in Cryptococcal Meningitis Unknown status NCT02686853 Phase 4 Liposomal amphotericin B
2 Safety, Efficacy, and Pharmacokinetics of Amphotericin B Lipid Complex Completed NCT01656382 Phase 4 ABLC
3 Operational Research for Cryptococcal Antigen Screening Completed NCT01535469 Phase 4 Fluconazole
4 A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal Infections Completed NCT00647907 Phase 4 Voriconazole
5 Optimal Time to Start Antiretroviral Therapy in HIV-infected Adults With Cryptococcal Meningitis Completed NCT00976040 Phase 4
6 Efficacy of Itraconazole as Secondary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation or Chemotherapy With Prior Invasive Fungal Infection Completed NCT01198236 Phase 4 Itraconazole
7 Cryptococcal Optimal ART Timing Trial Completed NCT01075152 Phase 4 efavirenz
8 Efficacy, Safety and Pharmacokinetics of SPK-843 in the Treatment of Pulmonary Mycosis Unknown status NCT01125644 Phase 3 SPK-843
9 Open Label Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P00041) Completed NCT00034658 Phase 3 Posaconazole
10 Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081) Completed NCT00000676 Phase 3 Clotrimazole;Fluconazole
11 Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P02095) Completed NCT00034632 Phase 3 Posaconazole oral suspension
12 A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection Completed NCT00784368 Phase 3 ITCZ Oral Solution;ITCZ-IV
13 Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS Completed NCT00001017 Phase 3 Fluconazole;Amphotericin B
14 Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis Completed NCT01802385 Phase 3 Sertraline
15 Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC Completed NCT01589289 Phase 3
16 Cryptococcal Antigen Screening Plus Sertraline Recruiting NCT03002012 Phase 3 Sertraline;Placebo Oral Tablet;Fluconazole
17 Study Evaluating Efficiency and Tolerance of High-dose Fluconazole Associated With Flucytosine as Induction Therapy for Cryptococcal Meningitis Associated With HIV in Sub-saharan Africa Active, not recruiting NCT01715922 Phase 2, Phase 3 Fluconazole;Flucytosine
18 Clinical Study of AK1820 (Isavuconazonium Sulfate) for the Treatment of Deep Mycosis Not yet recruiting NCT03471988 Phase 3 AK1820;Voriconazole
19 PK/PD Study of Posaconazole for Empiric Treatment of Invasive Fungal Infections in Neutropenic Patients or Treatment of Refractory Invasive Fungal Infections (Study P01893) Completed NCT00034671 Phase 2 Posaconazole oral suspension
20 High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected Individuals Completed NCT00885703 Phase 1, Phase 2 Fluconazole;Amphotericin B
21 Dexamethasone in Cryptococcal Meningitis Completed NCT00000776 Phase 2 Flucytosine;Fluconazole;Amphotericin B;Dexamethasone
22 Amphotericin Alone or in Combination With Fluconazole for AIDS-Associated Meningitis Completed NCT00145249 Phase 2 Amphotericin B;Fluconazole
23 Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis Completed NCT00012467 Phase 2 Itraconazole;Flucytosine;Fluconazole;Amphotericin B;Interferon gamma-1b
24 Treatment With Tamoxifen in Cryptococcal Meningitis Not yet recruiting NCT03112031 Phase 2 Tamoxifen;Amphotericin B;Fluconazole
25 Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS Terminated NCT00847678 Phase 2
26 Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS Terminated NCT00324025 Phase 2 Mycograb;placebo
27 SCH 39304 as Therapy for Acute Cryptococcal Meningitis in HIV-Infected Patients Followed by Maintenance Therapy Completed NCT00000677 Phase 1 SCH 39304
28 The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis Completed NCT00002316 Phase 1 Lobradimil;Amphotericin B
29 Vietnam Cryptococcal Retention in Care Study (CRICS) Federal Financial Report Recruiting NCT02955862 Phase 1
30 Clinical Trial of Pulmonary Cryptococcosis in China Unknown status NCT02503449
31 Liposomal Amphotericin B for the Treatment of Cryptococcal Meningitis Unknown status NCT02136030 Liposomal amphotericin B;Amphotericin B-deoxycholate
32 Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Cryptococcus Neoformans Infection in Patients Not Infected With HIV and Complications Associated With Cryptococcus Neoformans Infection Completed NCT00001701
33 A Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal Meningitis Completed NCT00000639 Itraconazole;Flucytosine;Fluconazole;Amphotericin B
34 A Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected Patients Completed NCT00002438 Itraconazole
35 Nevirapine Levels and Fluconazole Completed NCT00309582
36 A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients With AIDS Completed NCT00002294 Fluconazole
37 Multi-center Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis Completed NCT00000708 Flucytosine;Fluconazole;Amphotericin B
38 A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis. Completed NCT00002113 Flucytosine;Fluconazole
39 A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients Who Have Not Had Success With Amphotericin B Completed NCT00002306 Fluconazole
40 Pilot Study of Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis Completed NCT00002076 Fluconazole
41 Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Maintenance Treatment for the Prevention of Relapse of Cryptococcal Meningitis in Patients With Acquired Immunodeficiency Syndrome Completed NCT00002074 Fluconazole;Amphotericin B
42 Safety and Efficacy of Amphotericin B Lipid Complex in the Treatment of Cryptococcal Meningitis in Patients With the Acquired Immunodeficiency Syndrome Completed NCT00002019 Amphotericin B, Lipid-based;Amphotericin B
43 A Comparison of Fluconazole and Amphotericin B in the Treatment of Cryptococcal Meningitis Completed NCT00002305 Flucytosine;Fluconazole;Amphotericin B
44 Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis Completed NCT00002075 Flucytosine;Fluconazole;Amphotericin B
45 A Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis Completed NCT00002068 Fluconazole;Amphotericin B
46 An Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis Completed NCT00002077 Fluconazole
47 Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis Completed NCT00002040 Fluconazole
48 Clinical Outcomes of Cryptococcal Meningitis Among HIV-infected Patients in the Era of Antiretroviral Therapy Completed NCT02098525
49 Early Versus Delayed Antiretroviral Therapy (ART) in the Treatment of Cryptococcal Meningitis in Africa Completed NCT00830856 Fluconazole;Fixed dose - Stavudine, lamivudine and Nevirapine;Fixed dose - Stavudine, Lamivudine, Nevirapine
50 Evaluation and Follow-up of Patients With Cryptococcosis Recruiting NCT00001352

Search NIH Clinical Center for Cryptococcosis

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: cryptococcosis

Genetic Tests for Cryptococcosis

Anatomical Context for Cryptococcosis

MalaCards organs/tissues related to Cryptococcosis:

38
Lung, Liver, Testes, Bone, Brain, Kidney, T Cells

Publications for Cryptococcosis

Articles related to Cryptococcosis:

(show top 50) (show all 685)
# Title Authors Year
1
Miliary tuberculosis with co-existing pulmonary cryptococcosis in non-HIV patient without underlying diseases: a case report. ( 29338706 )
2018
2
Epidemiological trends of cryptococcosis in Italy: Molecular typing and susceptibility pattern of Cryptococcus neoformans isolates collected during a 20-year period. ( 29373716 )
2018
3
Disseminated cryptococcosis presenting initially as lower limb cellulitis in a renal transplant recipient - a case report. ( 29374464 )
2018
4
Antibody and B Cell Subset Perturbations in Human Immunodeficiency Virus-Uninfected Patients With Cryptococcosis. ( 29354657 )
2018
5
Cutaneous Cryptococcosis Mimicking Leishmaniasis. ( 29342402 )
2018
6
Cryptococcosis mimicking lung carcinoma with brain metastases in an immunocompetent patient. ( 27769644 )
2017
7
High-dose fluconazole in combination with amphotericin B is more efficient than monotherapy in murine model of cryptococcosis. ( 28680034 )
2017
8
Multicentric Cryptococcosis in a Congo African Grey Parrot ( Psittacus erithacus erithacus). ( 29327953 )
2017
9
Cryptococcosis: The Ubiquitous Yeast. ( 29319241 )
2017
10
Cryptococcosis in Patients with Nephrotic Syndrome: A Pooled Analysis of Cases. ( 28054218 )
2017
11
Pulmonary cryptococcosis in a ruxolitinib-treated patient with primary myelofibrosis. ( 28721333 )
2017
12
Disseminated cryptococcosis as a complication of lupus nephritis. ( 29265061 )
2017
13
Pleuro-pulmonary Cryptococcosis without Pleural Effusion. ( 28792175 )
2017
14
A case of disseminated cryptococcosis with necrotizing fasciitis in a non-HIV patient. ( 29123908 )
2017
15
Cryptococcosis in HIV-negative Patients with Renal Dialysis: A Retrospective Analysis of Pooled Cases. ( 28667348 )
2017
16
Evaluation of a Cryptococcal antigen Lateral Flow Assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia. ( 29267584 )
2017
17
Fluconazole Non-susceptible Cryptococcus neoformans, Relapsing/Refractory Cryptococcosis and Long-term Use of Liposomal Amphotericin B in an AIDS Patient. ( 28656554 )
2017
18
Clinical characteristics and prognosis of pediatric cryptococcosis in Beijing Children's Hospital, 2002-2014. ( 28776195 )
2017
19
Cryptococcosis and cryptococcal meningitis: New predictors and clinical outcomes at a United States academic medical centre. ( 29284182 )
2017
20
Acridine orange fluorescent microscopy is more sensitive than India ink light microscopy in the rapid detection of cryptococcosis among CrAg positive HIV patients. ( 28750078 )
2017
21
Laryngeal Cryptococcosis Associated With Inhaled Corticosteroid Use: Case Reports and Literature Review. ( 29209614 )
2017
22
Atypical Morphology and Disparate Speciation in a Case of Feline Cryptococcosis. ( 28756537 )
2017
23
Opportunistic Invasive Mycoses in AIDS: Cryptococcosis, Histoplasmosis, Coccidiodomycosis, and Talaromycosis. ( 28831671 )
2017
24
Unusual case of coexistent pulmonary cryptococcosis and tuberculosis in an immuno-competent host. ( 28709495 )
2017
25
Pulmonary Cryptococcosis Presenting With Lung Mass: Report of 7 Cases and Review of Literature. ( 28814908 )
2017
26
Disseminated cryptococcosis in an immunocompetent patient. ( 28720691 )
2017
27
Cryptococcus (Cryptococcosis) ( 28613714 )
2017
28
Clinical features of pulmonary cryptococcosis among patients with different levels of peripheral blood CD4<sup>+</sup>T lymphocyte counts. ( 29237413 )
2017
29
Cryptococcosis in a transplanted kidney allograft. ( 29340474 )
2017
30
Clinical Diversity of CNS Cryptococcosis. ( 29319242 )
2017
31
Vaccination with Recombinant<i>Cryptococcus</i>Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species. ( 29184017 )
2017
32
Disseminated Cryptococcosis in an Immunocompetent Child. ( 28044302 )
2017
33
Cryptococcus (Cryptococcosis), Cutaneous ( 28846364 )
2017
34
Image Gallery: Cutaneous presentation of disseminated cryptococcosis in a patient with undiagnosed HIV infection. ( 28940286 )
2017
35
Magnetic resonance imaging findings in central nervous system cryptococcosis: comparison between immunocompetent and immunocompromised patients. ( 29307925 )
2017
36
First report of two cases of cryptococcosis in Tripoli, Libya, infected with Cryptococcus neoformans isolates present in the urban area. ( 28576330 )
2017
37
Dermoscopic observations in disseminated cryptococcosis with cutaneous involvement. ( 29224242 )
2017
38
Disseminated cryptococcosis with skin lesions: report of a case series. ( 29267451 )
2017
39
Disseminated cryptococcosis presenting as cellulitis. ( 27779149 )
2017
40
Cryptococcosis in patients with hematological diseases: a 14-year retrospective clinical analysis in a Chinese tertiary hospital. ( 28673256 )
2017
41
First report of canine systemic cryptococcosis owing to Cryptococcus gattii in Europe. ( 27868198 )
2017
42
Disseminated Cryptococcosis with Severe Increased Intracranial Pressure Complicated with Cranial Nerve Palsy in a Child. ( 29189676 )
2017
43
Modulatory effect of voriconazole on the production of proinflammatory cytokines in experimental cryptococcosis in mice with severe combined immunodeficiency. ( 29273275 )
2017
44
Disseminated Cryptococcosis Mimicking Miliary Tuberculosis with Generalized Lymphadenopathy in Immunocompetent Host. ( 28782323 )
2017
45
Tuberculosis/cryptococcosis co-infection in China between 1965 and 2016. ( 28831193 )
2017
46
Cryptococcosis in patients with diabetes mellitus II in mainland China: 1993-2015. ( 28857298 )
2017
47
Identification of Disseminated Cryptococcosis Using MALDI-TOF MS and Clinical Evaluation. ( 27581774 )
2016
48
Localized Cutaneous Cryptococcosis: Summary of Reported Cases in Japan. ( 27581773 )
2016
49
Cytological diagnosis of biliary cryptococcosis in an immunocompromised patient with mid common bile duct stricture masquerading as cholangiocarcinoma. ( 27592857 )
2016
50
Common invasive fungal diseases: an overview of invasive candidiasis, aspergillosis, cryptococcosis, and Pneumocystis pneumonia. ( 26901377 )
2016

Variations for Cryptococcosis

Expression for Cryptococcosis

Search GEO for disease gene expression data for Cryptococcosis.

Pathways for Cryptococcosis

Pathways related to Cryptococcosis according to GeneCards Suite gene sharing:

(show all 18)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.73 CARD9 CLEC6A FCGR2A FCGR3A FCGR3B IFNG
2 12.34 CARD9 IFNG IL4 TLR9
3
Show member pathways
12.29 FCGR3A FCGR3B IFNG IL4
4
Show member pathways
11.95 IFNG IL4 TLR9
5
Show member pathways
11.93 FCGR2A FCGR3A FCGR3B IFNG IL4
6 11.89 FCGR2A FCGR3A FCGR3B MBL2
7 11.79 FCGR2A IFNG IL4
8 11.78 FCGR2A FCGR3A FCGR3B IFNG
9 11.69 FCGR2A IFNG IL4 SELL
10 11.69 CARD9 FCGR2A FCGR3A FCGR3B IFNG TLR9
11
Show member pathways
11.63 IFNG IL4 TLR9
12 11.58 FCGR2A FCGR3B TLR9
13 11.5 IFNG SELL TLR9
14 11.2 FCGR2A FCGR3A FCGR3B MBL2
15 11.08 IFNG IL4
16 11.04 IFNG IL4
17 10.96 IFNG IL4
18 10.84 FCGR2A FCGR3A FCGR3B IL4 TLR9

GO Terms for Cryptococcosis

Cellular components related to Cryptococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule membrane GO:0030667 8.8 FCGR2A FCGR3B SELL

Biological processes related to Cryptococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.46 FCGR3A FCGR3B IFNG IL4
2 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.13 CARD9 CLEC6A TLR9
3 positive regulation of interleukin-12 production GO:0032735 8.62 IFNG TLR9

Molecular functions related to Cryptococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 IgG binding GO:0019864 8.8 FCGR2A FCGR3A FCGR3B

Sources for Cryptococcosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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