MCID: CRY002
MIFTS: 57

Cryptorchidism malady

Categories: Genetic diseases (common), Reproductive diseases

Aliases & Classifications for Cryptorchidism

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Aliases & Descriptions for Cryptorchidism:

Name: Cryptorchidism 49 10 11 47 12 67 36
Cryptorchidism, Unilateral or Bilateral 24
Impaired Testicular Descent 67
Undescended Testicles 10
Undescended Testicle 10
 
Undescended Testis 10
Cryptosporidiosis 65
Cryptorchism 10
Crypto 67

Classifications:



External Ids:

OMIM49 219050
Disease Ontology10 DOID:11383
ICD9CM29 752.51
MeSH36 D003456
NCIt42 C12326
MedGen34 C0010417
UMLS65 C0010417

Summaries for Cryptorchidism

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OMIM:49 Cryptorchidism, or failure of testicular descent, is a common human congenital abnormality with a multifactorial... (219050) more...

MalaCards based summary: Cryptorchidism, also known as cryptorchidism, unilateral or bilateral, is related to pseudohermaphroditism and seminoma, and has symptoms including unilateral cryptorchidism, renal agenesis and pruritus. An important gene associated with Cryptorchidism is INSL3 (Insulin Like 3), and among its related pathways are Hormone ligand-binding receptors and IL-6 Signaling Pathway. The drug nitazoxanide has been mentioned in the context of this disorder. Affiliated tissues include testis, testes and breast, and related mouse phenotypes are reproductive system and endocrine/exocrine gland.

UniProtKB/Swiss-Prot:67 Cryptorchidism: One of the most frequent congenital abnormalities in humans, involving 2-5% of male births. Cryptorchidism is associated with increased risk of infertility and testicular cancer.

Wikipedia:68 Cryptorchidism is the absence of one or both testes from the scrotum. It is the most common birth defect... more...

Related Diseases for Cryptorchidism

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Diseases related to Cryptorchidism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 199)
idRelated DiseaseScoreTop Affiliating Genes
1pseudohermaphroditism30.8AR, CGA, SHBG
2seminoma30.5ALPP, ALPPL2
3pfeiffer syndrome30.1ALPPL2, CGB5, NR5A1
4hypogonadism29.9AMH, AR, GNRH1, SHBG
5malignant tumor of undescended testis12.4
6torticollis keloids cryptorchidism renal dysplasia11.9
7anophthalmia esophageal atresia cryptorchidism11.8
8cryptorchidism arachnodactyly mental retardation11.8
9cryptorchidism-arachnodactyly-intellectual disability syndrome11.8
10intellectual disability-craniofacial dysmorphism-cryptorchidism syndrome11.8
11intellectual disability-hypotonia-brachycephaly-pyloric stenosis-cryptorchidism syndrome11.8
12spigelian hernia-cryptorchidism syndrome11.8
13x-linked microcephaly-growth retardation-prognathism-cryptorchidism syndrome11.8
14prune belly syndrome11.6
15fetal akinesia deformation sequence11.2
16ifap syndrome with or without bresheck syndrome11.2
17mcdonough syndrome11.1
18pseudoachondroplastic dysplasia 210.9RAF1, SOS1
19rad21-related cornelia de lange syndrome10.9RAF1, SOS1
20cryptosporidiosis10.8
21arroyo garcia cimadevilla syndrome10.8
22caudal appendage deafness10.8
23duker weiss siber syndrome10.8
24ichthyosis and male hypogonadism10.8
25singh chhaparwal dhanda syndrome10.8
26van benthem-driessen-hanveld syndrome10.8
27bresek syndrome10.8
28background diabetic retinopathy10.8AR, GNRH1
29short qt syndrome10.7AMH, INSL3, NR5A1
30uremic neuropathy10.7AMH, GNRH1
31penoscrotal transposition10.6AR, CGA, GNRH1
32craniofrontonasal dysplasia10.6AR, SHBG
33zap70-related severe combined immunodeficiency10.6AZF1, DAZ1
34leiomyoma10.6AR, CGA, SHBG
35geroderma osteodysplastica10.6ALPP, CGA, CGB5
36scleromalacia perforans10.5AR, DAZ1, SHBG
37ovarian hyperstimulation syndrome10.5AMH, CGA, GNRH1
38hypospadias10.5
39pleomorphic xanthoastrocytoma10.5FGFR1, RAF1, SOS1
40anaerobic meningitis10.5ALPP, ALPPL2
41breast adenocarcinoma10.5ALPP, ALPPL2
42cervical adenitis10.5ALPP, ALPPL2
43internal auditory canal meningioma10.5ALPP, ALPPL2
44external ear disease10.5CGA, GNRH1, SHBG
45malignant histiocytosis10.5ALPP, ALPPL2
4646 xy gonadal dysgenesis10.4AMH, NR5A1, SHBG
47anorectal atresia10.4CGA, CGB5, INSL3, NR5A1, RXFP2
48angiostrongyliasis10.4ALPP, ALPPL2
49achondrogenesis10.4ALPP, ALPPL2
50postgastrectomy syndrome10.4ALPP, ALPPL2

Graphical network of the top 20 diseases related to Cryptorchidism:



Diseases related to cryptorchidism

Symptoms for Cryptorchidism

About this section

Symptoms by clinical synopsis from OMIM:

219050

Clinical features from OMIM:

219050

HPO human phenotypes related to Cryptorchidism:

id Description Frequency HPO Source Accession
1 unilateral cryptorchidism HP:0012741
2 renal agenesis HP:0000104

UMLS symptoms related to Cryptorchidism:


pruritus

Drugs & Therapeutics for Cryptorchidism

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Drugs for Cryptorchidism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Propofolapproved, investigationalPhase 49312078-54-84943
Synonyms:
2, 6-Diisopropylphenol
2,6 Diisopropylphenol
2,6-Bis(1-methylethyl)phenol
2,6-Bis(Isopropyl)-phenol
2,6-DIISOPROPYLPHENOL
2,6-Diisopropyl phenol
2,6-Diisopropylphenol
2,6-bis(1-methylethyl)-phenol
2,6-di(propan-2-yl)phenol
2078-54-8
28449-97-0
4-06-00-03435 (Beilstein Handbook Reference)
50356-15-5
AB00513968
AC-2038
AC1L1J9Y
AC1Q1OUI
AI3-26295
AM-149
Abbott Brand of Propofol
Alpha Brand of Propofol
Ampofol
Aquafol
Astra Brand of Propofol
AstraZeneca Brand of Propofol
BIDD:GT0436
BPBio1_000950
BPBio1_000969
BRD-K82255054-001-03-5
BRN 1866484
BSPBio_000862
Biomol-NT_000248
Braun Brand of Propofol
C07523
C12H18O
CAS-2078-54-8
CCRIS 9000
CHEBI:44915
CHEMBL526
CID4943
CPD-11437
CPD000059151
Curamed Brand of Propofol
D00549
D015742
D0617
D126608
D126608_ALDRICH
DB00818
DDS-04F
Diisopropylphenol
Dipravan
Diprivan
Diprivan (TN)
Diprivan Injectable emulsion
Disoprivan
Disoprofol
EINECS 218-206-6
EU-0100437
Fresenius Brand of Propofol
Fresenius Kabi Brand of Propofol
Fresofol
HMS1570L04
HMS2089O21
HMS2094E17
 
HSDB 7123
ICI 35,868
ICI 35868
ICI-35,868
ICI-35868
ICI35,868
ICI35868
InChI=1/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H
Ivofol
Jsp004266
Juste Brand of Propofol
LS-996
Lopac-D126608
Lopac0_000437
MLS001066348
MLS001335999
MLS002454360
MolPort-001-794-517
NCGC00015389-01
NCGC00015389-02
NCGC00015389-04
NCGC00015389-09
NCGC00091538-01
NCGC00091538-02
NCGC00091538-03
NCGC00091538-04
NCGC00091538-05
NCGC00091538-06
NSC 5105
NSC5105
PFL
Parnell Brand of Propofol
Pisa Brand of Propofol
Prestwick0_000931
Prestwick1_000931
Prestwick2_000931
Prestwick3_000931
Propofol
Propofol (JAN/USAN/INN)
Propofol Abbott
Propofol Fresenius
Propofol IDD-D
Propofol MCT
Propofol Rovi
Propofol [USAN:INN:BAN]
Propofol(2,6-Diisopropylphenol)
Propofol-Lipuro
Propofolum
Propofolum [Latin]
Rapinovet
Recofol
Rovi Brand of Propofol
S01-0189
SAM002264610
SMR000059151
SPBio_003031
SPECTRUM1505022
ST50405911
Schering Brand of Propofol
UNII-YI7VU623SF
W505102_ALDRICH
ZD-0859
ZINC00968303
Zeneca Brand of Propofol
ghl.PD_Mitscher_leg0.558
nchembio.552-comp7
propofol
2
SevofluraneapprovedPhase 4, Phase 242928523-86-65206
Synonyms:
1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
28523-86-6
AC-15484
AC1L1JU0
BRN 2041023
Bax 3084
C009250
C07520
C4H3F7O
CHEBI:9130
CHEMBL1200694
CID5206
D00547
DB01236
F0691
Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether
Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
I14-13357
LS-67851
MR6S4
 
MR_6S4
MolPort-001-775-746
NCGC00167421-01
PC4681
Sevofluran
Sevoflurane
Sevoflurane (JAN/USAN/INN)
Sevoflurane [USAN:INN:BAN:JAN]
Sevoflurano
Sevoflurano [INN-Spanish]
Sevofluranum
Sevofluranum [INN-Latin]
Sevofrane
Sevorane
Sojourn
UNII-38LVP0K73A
Ultane
Ultane (TN)
ZINC01530810
fluoromethyl hexafluoroisopropyl ether
fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
sevoflurane
3Anesthetics, IntravenousPhase 41943
4Anesthetics, GeneralPhase 4, Phase 22274
5Hypnotics and SedativesPhase 4, Phase 22032
6AnestheticsPhase 4, Phase 27385
7Central Nervous System DepressantsPhase 4, Phase 210016
8
DexmedetomidineapprovedPhase 2470113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
Dexdor (T)
 
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidine Hydrochloride
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex
Precedex (TN)
Tocris-2023
ZINC04632106
9
BenzocaineapprovedPhase 216841994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
20/20 Topical Anesthetic
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Alcohol Prep Pads
Allegenal-m
Alpha-caine Topical Anesthetic
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anbesol Jr
Anbesol Maximum Strength
Anbesol Regular Strength
Anestenka
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthetic
Anesthone
Atopalm Oral Pain Relief
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Baby Anestenka
Baby Sensigel
Baby Sensigel Night Time Formula
Baby Teething Oral Pain Reliever
Bactimicina For Sore Throat
Bencocaine Topical Anesthetic
Bensokain
Benz O Sthetic
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzodent
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
Boil Ease
Boy Butter Desensitizing Lubricant
Boy Butter Extreme Desensitizing Lubricant
Boy Butter Extreme H2O Desensitizing Lubricant
Brace Relief
Budpak Baby Teething Oral Pain Reliever
Budpak Oral Maximum Strength
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Carmex Cold Sore Treatment External Analgesic
Caswell No. 430A
Cepacol Fizzlers
Cepacol Sensations Hydra
Cepacol Sensations Sore Throat Hydra citrus splash
Cepacol Sensations Warming
Certus Sting Relief Prep Pad
Chloraseptic
Chloraseptic Warming Sore Throat
Colgate Orabase
Comfortcaine Topical Anesthetic
Cvs Fast Acting Baby Teething
Cvs Maximum Strength
Cvs Maximum Strength Boil Relief
Cvs Oral Anesthetic
Cvs Pharmacy Instant Toothache
Cvs Pharmacy Maximum Strength
Cvs Pharmacy Mouth Sore Gel
Cvs Pharmacy Nighttime Oral Pain Relief
D001566
D00552
DB01086
Dental Relief
Dentek Instant Pain Relief Maximum Strength
Dermoplast
Diet Ayds
DivK1c_000932
Dollar General Toothache Relief
Dukal Sting Relief Pad
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Finafta Baby
Finafta MultiOral
Formate, Benzocaine
Gelato Topical Anesthetic
Good Neighbor Pain Relief
Goodsense Oral Pain Relief
Gps Topical Anesthetic
Gumnumb Topical Anesthetic
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Heb Severe Toothache
Herbasoul Male Genital Desensitizer Cream
 
Hurricaine
Hurricaine Topical Anesthetic
Hurricaine Topical Anesthetic Gel
Hurricaine Topical Anesthetic Liquid
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
Insect Bite Relief
Instant Toothache Pain Relief
Intense Cvs Intense Toothache
Iodent Maximum Strength Oral Analgesic
Ismile Topical Anesthetic
Jianze Sting Relief Pads
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Kank-a Mouth Pain
Keloform
Kmart Smart Sense
Kroger Toothache Pain Relief
LS-35847
Leader Oral Analgesic
Little Colds Sore Throat Relief Melt Aways
MLS001331704
MLS002153970
Makesense Junior Pain Relief
Makesense Pain Relief
Male Desensitizer Pleasure Balm
Mandelay Male Genital Desensitizer
Mark 3
Methanesulfonate, Benzocaine
MolPort-000-871-526
Mouth Sore Medication
Mouth Sore Relief Applicator
Mouth Sore Relief Professional Strength
My Fair Baby Instant Pain Relief
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Nene Dente
Norcain
Norcaine
Norcainum
Opahl
Opahl Dye Free
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orajel For All Mouth Sores Maximum Strength
Orajel For Cold Sores
Orajel For Toothache Maximum Strength
Orajel Instant Pain Relief Maximum Strength
Orajel Instant Pain Relief Regular Strength
Orajel Instant Relief For Teething Pain
Orajel Instant Relief For Teething Pain Cooling Cucumber
Orajel Instant Relief For Teething Pain Daytime Nighttime Twin Pack
Orajel Instant Relief For Teething Pain Longer Lasting
Orajel Maximum Strength
Orajel Nighttime Instant Relief For Teething Pain Longer Lasting Extra Strength
Orajel Severe Toothache Maximum Strength Fast-Acting Formula
Oral Analgesic Maximum Strength
Oral B Instant Pain Relief
Oral Gel Maximum Strength
Oral Pain Relief Anesthetic Anesthetic
Oral Pain Reliever
Oralabs Cold Sore Treatment
Orthesin
Otocain
Outgro
Pac-dent Top Gel
Pain Relief
Pain Relief Alcohol Swabs
Parathesin
Parathesin (TN)
Parathesine
Physicians Care Sting Relief Pad
Pleasure Balm Kama Sutra
Preboost
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
Purelife Topical Anesthetic
Quality Choice Maximum Strength Oral Pain Relieving
Red Cross Oral Pain Relief
Rexall Maximum Strength
Rite Aid Baby Care
Rite Aid Liquid Anesthetic Oral Pain Relief
Rite Aid Maximum Strength
Rite Aid Oral Pain Reliever
Rite Aid Professional Strength
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Sally Hansen Ouch-relief Numbing Wipes
Sally Hansen Ouch-relief Wax Kit
Sally Hansen Ouch-relief Wax Strip Kit
Sensigel
Severe Oral Pain Reliever
Sheffield Baby Teething Gel
Sheffield Pain Relief
Shunga Male Genital Desensitizer
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Sting Relief Medicated Pad
Sting Relief Pads
Tanac
Terrasil Boil Pain Relief
Tiger Supply Inc Topical Anesthetic
Top Quality Mfg. Topical Anesthetic
Topcaine
Topcare Maximum Strength
Topical Anesthetic Banana
Topical Anesthetic Bubble Gum
Topical Anesthetic Cherry
Topical Anesthetic Mint
Topical Anesthetic Pina Colada
Topical Anesthetic Raspberry
Topical Anesthetic Strawberry
UNII-U3RSY48JW5
Ultracare Anesthetic Bubble Gum
Ultracare Anesthetic Butter Rum
Ultracare Anesthetic Creme de Menthe
Ultracare Anesthetic Pina Colada
Ultracare Anesthetic Walterberry
WLN: ZR DVO2
Walgreens Baby Teething
Walgreens Intense Toothache
Walgreens Maximum Strength
Walgreens Pain Relieving For Boils
Walgreens Severe Oral Pain Reliever
Walgreens Severe Toothache Relief
Winco Foods Maximum Strength Oral Analgesic
ZINC12358719
Zilactin-b
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
10
LevobupivacaineapprovedPhase 214627262-47-192253
Synonyms:
(-)-Bupivacaine
(-)-bupivacaine
(2S)-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(S)-1-Butyl-2',6'-pipecoloxylidide
(S)-Bupivacaine
(S)-bupivacaine
27262-47-1
27262-48-2
AC1L3NQM
BIDD:GT0471
C07887
C18H28N2O
CAS-18010-40-7
CHEBI:6149
CID92253
D08116
 
DB01002
L(-)-Bupivacaine
L-(-)-1-Butyl-2',6'-pipecoloxylidide
L-(-)-Bupivacaine
L-(-)-bupivacaine
LS-109843
LS-187025
LS-187789
Levobupivacaine
Levobupivacaine (INN)
Levobupivacaine [INN:BAN]
Levobupivacaine hydrochloride
MolPort-004-959-713
NCGC00016733-01
NCGC00159482-02
Novabupi
Novabupi (TN)
11
Bupivacaineapproved, investigationalPhase 29642180-92-92474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Hydrochloride
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
DepoBupivacaine
 
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
Exparel
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
Racemic bupivacaine
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Vivacaine
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
12NarcoticsPhase 22709
13Platelet Aggregation InhibitorsPhase 21935
14Neurotransmitter AgentsPhase 214795
15Peripheral Nervous System AgentsPhase 218510
16Adrenergic alpha-2 Receptor AgonistsPhase 2790
17Adrenergic AgonistsPhase 22331
18Anesthetics, LocalPhase 22347
19Adrenergic alpha-AgonistsPhase 21300
20Adrenergic AgentsPhase 24204
21AnalgesicsPhase 29358
22Analgesics, Non-NarcoticPhase 25184
23Anesthetics, InhalationPhase 2511
24tannic acidNutraceuticalPhase 21684
25
Dexamethasoneapproved, investigational190950-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Baycadron
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
Dexameth
Dexamethansone
 
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone acetate
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone sodium phosphate
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamethsone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
Ozurdex
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
26
Ropivacaineapproved65084057-95-471273, 175805
Synonyms:
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
(S)-(−)-1-propyl-2',6'-pipecoloxylidide
(S)-ropivacaine
84057-95-4
98717-15-8
AC1L41QM
AC1L41QN
BIDD:GT0203
C07532
C17H26N2O.HCl
CHEBI:8890
CHEMBL1077896
CID175804
CID175805
CPD000469137
D08490
I14-176
L-N-n-propylpipecolic acid-2,6-xylidide
LS-113954
 
MLS001401363
MolPort-003-983-292
NCGC00164597-01
Naropin
Naropin (TN)
ROPIVACAINE HCl
Ropivacaina
Ropivacaina [INN-Spanish]
Ropivacaina [Spanish]
Ropivacaine
Ropivacaine Hydrochloride
Ropivacaine [INN]
Ropivacaine hydrochloride
Ropivacaine monohydrochloride
Ropivacainum
Ropivacainum [INN-Latin]
S-Ropivacaine
SAM001246524
SMR000469137
ST51051452
ropivacaine monohydrochloride,
ropivacaine monohydrochloride, (S)-isomer
27HIV Protease Inhibitors4558
28Hormones11748
29Hormone Antagonists10002
30Protease Inhibitors4558
31glucocorticoids3896
32Hormones, Hormone Substitutes, and Hormone Antagonists9988
33BB 11011909
34Anti-Inflammatory Agents8478
35Antiemetics3213
36Gastrointestinal Agents6401
37Antineoplastic Agents, Hormonal4256
38Dexamethasone 21-phosphate1909
39Dexamethasone acetate19091177-87-3
40Estrogens2144
41Androgens1162

Interventional clinical trials:

(show all 19)
idNameStatusNCT IDPhase
1The Effect of Induction Technique on Postoperative Pain and AgitationCompletedNCT02110745Phase 4
2Caudal Versus Intravenous Dexmedetomidine for Supplementation of Caudal Analgesia in ChildrenCompletedNCT01701778Phase 2
3Comparing Oxygen Saturation in Post Anesthesia Care Unit After Different Methods of Pain ReliefCompletedNCT00435383Phase 2
4Cryptorchidism: Impact of in Utero Exposure to Xenobiotics With Hormonal ActionCompletedNCT00565513
5A Novel Technique of Circumcision Incision OrchidopexyCompletedNCT02249637
6Long-Term Outcome in Congenital Undescended Testis After Surgical Treatment by OrchidopexyCompletedNCT00253253
7The Caudal Space in Children: Ultrasound EvaluationCompletedNCT01896076
8Comparison of Dexamethasone Added to Ropivacaine and Ropivacaine Alone in Caudal Analgesia in Children Undergoing OrchiopexyCompletedNCT01604915
9A Case-Control Study of Testicular Germ Cell Tumors Among U.S. Military ServicemenCompletedNCT00341588
10Genetics of Familial Testicular CancerCompletedNCT00342537
11The Incidence of Congenital Undescended Testis Among Dutch InfantsRecruitingNCT00264121
12Orchidopexy Randomized Clinical AssessmentRecruitingNCT02235623
13Expertise-Based Randomized Control Trial of Scrotal Versus Inguinal Orchidopexy on Post-operative PainRecruitingNCT02158780
14Visual Guidelines and Tutoring in Pediatric Urological SurgeryRecruitingNCT02040389
15The Genetic Investigation of Reproductive Disorders (Including Kallmann Syndrome)RecruitingNCT01601171
16Can the Hypertrophy of Contralateral Testis Predict the Absence of the Non-palpable Testis in the Boys Aged From 6months to 18months of Age ?RecruitingNCT02203318
17DNA Analysis in Samples From Younger Patients With Germ Cell Tumors and Their Parents or SiblingsRecruitingNCT01434355
18Odense Androgen Study: Study of Androgens, Body Composition, and Muscle Function in Danish MenActive, not recruitingNCT00150163
19Comparison Between the Clinical Assessment of the Undescended Testis and Its' Ultrasonographic SizeNot yet recruitingNCT02731989

Search NIH Clinical Center for Cryptorchidism

Inferred drug relations via UMLS65/NDF-RT43:


Cochrane evidence based reviews: cryptorchidism

Genetic Tests for Cryptorchidism

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Anatomical Context for Cryptorchidism

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MalaCards organs/tissues related to Cryptorchidism:

33
Testis, Testes, Breast, Kidney, Brain, Bone, Lung

Animal Models for Cryptorchidism or affiliated genes

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MGI Mouse Phenotypes related to Cryptorchidism:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.6ALPPL2, AMH, AR, CGA, FGFR1, GNRH1
2MP:00053798.5AMH, AR, CGA, FGFR1, GNRH1, HOXA10

Publications for Cryptorchidism

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Articles related to Cryptorchidism:

(show top 50)    (show all 665)
idTitleAuthorsYear
1
The Mechanism of Environmental Endocrine Disruptors (DEHP) Induces Epigenetic Transgenerational Inheritance of Cryptorchidism. (26035430)
2015
2
The variations in the AXIN1 gene and susceptibility to cryptorchidism. (25802106)
2015
3
Laparoscopic treatment for inguinal hernia combined with cryptorchidism: Totally extraperitoneal repair with orchiectomy under the same operative view. (26581081)
2015
4
Snapshots in surgery: incidentally discovered cryptorchidism. (25614818)
2014
5
The management of bilateral cryptorchidism in the adult man: report of two cases. (25407156)
2014
6
Early Prenatal Detection of an Intra-abdominal Cryptorchid Testicular Teratoma. (24054441)
2014
7
Idiopathic scrotal hematoma simulating a testicular torsion, in association with cryptorchidism: US findings. (25061495)
2014
8
Epididymal-testicular fusion anomalies in cryptorchidism are associated with proximal location of the undescended testis and with a widely patent processus vaginalis. (25048056)
2014
9
A genome-wide association study for canine cryptorchidism in Siberian Huskies. (24268032)
2013
10
No association between exposure to perfluorinated compounds and congenital cryptorchidism: a nested case-control study among 215 boys from Denmark and Finland. (24218628)
2013
11
Cryptorchidism and testicular germ cell tumors: comprehensive meta-analysis reveals that association between these conditions diminished over time and is modified by clinical characteristics. (23423470)
2012
12
Management of cryptorchidism: a survey of clinical practice in Italy. (22233418)
2012
13
Serum AMH concentration as a marker evaluating gonadal function in boys operated on for unilateral cryptorchidism between 1st and 4th year of life. (22038452)
2012
14
Comment on "Serum AMH concentration as a marker evaluating gonadal function in boys operated on for unilateral cryptorchidism between 1st and 4th year of life". (22234386)
2012
15
Is laparoscopic re-evaluation justified in cryptorchidism with previous negative open exploration? (22168768)
2012
16
The controversy regarding the need for hormonal treatment in boys with unilateral cryptorchidism goes on: a review of the literature by B. Ludwikowski and R. GonzA!lez. (22527570)
2012
17
Laparoscopic testicular preservation in adults with intra-abdominal cryptorchidism: is it beneficial? (23227040)
2012
18
History of cryptorchidism and ejaculate volume as simple predictors for the presence of testicular sperm. (21284574)
2011
19
Impact of anatomical and socioeconomic factors on timing of urological consultation for boys with cryptorchidism. (21855921)
2011
20
Diagnostic performance of ultrasound in nonpalpable cryptorchidism: a systematic review and meta-analysis. (21149435)
2011
21
A missense mutation in LRR8 of RXFP2 is associated with cryptorchidism. (20963592)
2010
22
Variations in timing of surgery among boys who underwent orchidopexy for cryptorchidism. (20732947)
2010
23
Splenogonadal fusion presented with cryptorchidism. (19472134)
2009
24
Cryptorchidism with short spermatic vessels: staged orchiopexy preserving spermatic vessels. (19625047)
2009
25
Posterior urethral valves are often associated with cryptorchidism and inguinal hernias. (18554641)
2008
26
Maternal diet and the risk of hypospadias and cryptorchidism in the offspring. (18426520)
2008
27
Studies of cryptorchidism in experimental animal models. (17462054)
2007
28
Insulin-like factor 3 levels in cord blood and serum from children: effects of age, postnatal hypothalamic-pituitary-gonadal axis activation, and cryptorchidism. (17666478)
2007
29
Association of long polyglycine tracts (GGN repeats) in exon 1 of the androgen receptor gene with cryptorchidism and penile hypospadias in Iranian patients. (16957138)
2007
30
Mild gestational diabetes as a risk factor for congenital cryptorchidism. (17032715)
2006
31
Persistent pesticides in human breast milk and cryptorchidism. (16835070)
2006
32
Germ cell apoptosis induced by experimental cryptorchidism is mediated by multiple molecular pathways in Cynomolgus Macaque. (16146798)
2006
33
The incidence of bilateral cryptorchidism is increased and the fertility potential is reduced in sons born to mothers who have smoked during pregnancy. (16813933)
2006
34
Congenital Spigelian hernia with cryptorchidism: probably a new syndrome. (15782280)
2005
35
Role of INSL3 and LGR8 in cryptorchidism and testicular functions. (15353080)
2004
36
Maternal and paternal risk factors for cryptorchidism and hypospadias: a case-control study in newborn boys. (15531444)
2004
37
The INSL3-LGR8/GREAT ligand-receptor pair in human cryptorchidism. (12970298)
2003
38
Lack of LGR8 gene mutation in Finnish patients with a family history of cryptorchidism. (14656401)
2003
39
Absence of microdeletions in the Y chromosome in patients with Prader-Willi syndrome with cryptorchidism. (11869370)
2002
40
Cryptorchidism. (12518213)
2002
41
Leydig cell function after cryptorchidism: evidence of the beneficial result of early surgery. (11912442)
2002
42
Cryptorchidism: aspects of fertility and neoplasms. A study including data of 1,335 consecutive boys who underwent testicular biopsy simultaneously with surgery for cryptorchidism. (11423738)
2001
43
Controversy in cryptorchidism: the value of laparoscopy and fertility outcomes. (11397487)
2001
44
Cryptorchidism and Hypospadias (25905331)
2000
45
Association of epididymal anomalies with patent processus vaginalis in hernia, hydrocele and cryptorchidism. (8911389)
1996
46
Cryptorchidism in boys with imperforate anus. (7595851)
1995
47
Cryptorchidism]. (1361054)
1992
48
Evidence in favor of the mechanical (intrauterine torsion) theory over the endocrinopathy (cryptorchidism) theory in the pathogenesis of testicular agenesis. (1677689)
1991
49
X-linked ichthyosis and cryptorchidism. (2874061)
1986
50

Variations for Cryptorchidism

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UniProtKB/Swiss-Prot genetic disease variations for Cryptorchidism:

67
id Symbol AA change Variation ID SNP ID
1INSL3p.Pro93LeuVAR_013235rs104894697
2INSL3p.Arg102CysVAR_013236
3INSL3p.Asn110LysVAR_017122
4RXFP2p.Thr222ProVAR_015386rs28939382

Clinvar genetic disease variations for Cryptorchidism:

5
id Gene Variation Type Significance SNP ID Assembly Location
1INSL3NM_005543.3(INSL3): c.330C> G (p.Asn110Lys)single nucleotide variantPathogenicrs121912555GRCh37Chr 19, 17927729: 17927729
2INSL3NM_005543.3(INSL3): c.278C> T (p.Pro93Leu)single nucleotide variantPathogenicrs104894697GRCh37Chr 19, 17927781: 17927781
3INSL3NM_005543.3(INSL3): c.304C> T (p.Arg102Cys)single nucleotide variantPathogenicrs104894698GRCh37Chr 19, 17927755: 17927755
4INSL3NM_005543.3(INSL3): c.305G> A (p.Arg102His)single nucleotide variantPathogenicrs121912556GRCh37Chr 19, 17927754: 17927754
5INSL3NM_005543.3(INSL3): c.217C> T (p.Arg73Ter)single nucleotide variantPathogenicrs398122886GRCh37Chr 19, 17927842: 17927842

Expression for genes affiliated with Cryptorchidism

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Search GEO for disease gene expression data for Cryptorchidism.

Pathways for genes affiliated with Cryptorchidism

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GO Terms for genes affiliated with Cryptorchidism

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Biological processes related to Cryptorchidism according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1sex differentiationGO:000754810.4AMH, AR
2peptide hormone processingGO:001648610.2CGA, CGB5
3oocyte maturationGO:000155610.2INSL3, RXFP2
4regulation of gene expressionGO:001046810.2AR, FGFR1, GNRH1
5cell-cell signalingGO:00072679.3AR, CGA, CGB5, NR5A1

Sources for Cryptorchidism

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet