MCID: CTN013
MIFTS: 34

Cutaneous Anthrax malady

Categories: Rare diseases, Infectious diseases, Skin diseases

Aliases & Classifications for Cutaneous Anthrax

Aliases & Descriptions for Cutaneous Anthrax:

Name: Cutaneous Anthrax 12 50 42 14 69
Anthrax, Skin Type 50
Skin Anthrax 50

Classifications:



External Ids:

Disease Ontology 12 DOID:7426
ICD10 33 A22.0
ICD9CM 35 022.0
MeSH 42 C531621
SNOMED-CT 64 84980006
UMLS 69 C0003177

Summaries for Cutaneous Anthrax

Disease Ontology : 12 An anthrax disease that results_in infection located in skin, has material basis in Bacillus anthracis, which is transmitted_by contact with infected animals or animal products. The infection has symptom skin lesion that eventually forms an ulcer with a black center.

MalaCards based summary : Cutaneous Anthrax, also known as anthrax, skin type, is related to anthrax disease and infant botulism, and has symptoms including skin lesion An important gene associated with Cutaneous Anthrax is ADA (Adenosine Deaminase), and among its related pathways/superpathways are Glucose / Energy Metabolism and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include skin, t cells and testes.

Related Diseases for Cutaneous Anthrax

Diseases related to Cutaneous Anthrax via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
id Related Disease Score Top Affiliating Genes
1 anthrax disease 11.6
2 infant botulism 10.2 CD4 HSPD1
3 gastroenteritis 10.1 CD4 HSPD1
4 equatorial staphyloma 10.1 CD4 HSPD1
5 foodborne botulism 10.1 ADA CD4 HSPD1
6 inguinal hernia 10.1 CD4 ITGA2
7 lens-induced iridocyclitis 10.1 CD4 IL5
8 villonodular synovitis 10.0 ADA CD4
9 goodpasture syndrome 10.0 ADA CD4 HSPD1 PON1
10 hemolytic anemia 9.7
11 ulnar nerve lesion 9.7
12 cicatricial ectropion 9.7
13 ectropion 9.7
14 cerebritis 9.7
15 cellulitis 9.7
16 hypokalemia 9.7
17 transmitted_by 9.7
18 ovarian clear cell cystadenocarcinoma 7.8 ACOT13 ADA CASP1 CD4 DLD EEF1A1

Graphical network of the top 20 diseases related to Cutaneous Anthrax:



Diseases related to Cutaneous Anthrax

Symptoms & Phenotypes for Cutaneous Anthrax

Symptoms:

12
  • skin lesion

Drugs & Therapeutics for Cutaneous Anthrax

Interventional clinical trials:


id Name Status NCT ID Phase
1 Natural History of Anthrax: a Study of Primary Infected, Recovered, and Exposed Individuals (SPoRE); and Evaluation of AVA-Vaccinated Recipients Recruiting NCT00050310

Search NIH Clinical Center for Cutaneous Anthrax

Cochrane evidence based reviews: cutaneous anthrax

Genetic Tests for Cutaneous Anthrax

Anatomical Context for Cutaneous Anthrax

MalaCards organs/tissues related to Cutaneous Anthrax:

39
Skin, T Cells, Testes, Lymph Node, Brain

The Foundational Model of Anatomy Ontology organs/tissues related to Cutaneous Anthrax:

18
Skin

Publications for Cutaneous Anthrax

Articles related to Cutaneous Anthrax:

(show top 50) (show all 161)
id Title Authors Year
1
Evaluation of Clinical and Serological Findings For Diagnosis of Cutaneous Anthrax Infection after an Outbreak. ( 28076993 )
2017
2
An outbreak of cutaneous anthrax in Yunnan, China. ( 27329849 )
2016
3
Evaluation of cutaneous anthrax cases during an outbreak in the east region of Turkey. ( 27966316 )
2016
4
Cutaneous Anthrax. ( 27742398 )
2016
5
Serum paraoxonase activity and oxidative stress levels in patients with cutaneous anthrax. ( 27461010 )
2016
6
Cutaneous Anthrax on Eyelid in a Pregnant Woman. ( 27551179 )
2016
7
Source and risk factors of a cutaneous anthrax outbreak, Jiangsu, Eastern China, 2012. ( 27277672 )
2016
8
Human Cutaneous Anthrax, the East Anatolian Region of Turkey 2008-2014. ( 26720232 )
2016
9
Genome Sequence of Bacillus anthracis Larissa, Associated with a Case of Cutaneous Anthrax in Greece. ( 26564034 )
2015
10
Cutaneous anthrax in an unusual location: case report. ( 26700091 )
2015
11
Periorbital cellulitis due to cutaneous anthrax. ( 25763844 )
2015
12
Natural cutaneous anthrax infection, but not vaccination, induces a CD4(+) T cell response involving diverse cytokines. ( 26075052 )
2015
13
Spatiotemporal Clustering Analysis and Risk Assessments of Human Cutaneous Anthrax in China, 2005-2012. ( 26208355 )
2015
14
Development & validation of a quantitative anti-protective antigen IgG enzyme linked immunosorbent assay for serodiagnosis of cutaneous anthrax. ( 26354217 )
2015
15
A case of cutaneous anthrax presenting with classical lesions. ( 26340973 )
2015
16
Cutaneous anthrax: evaluation of 28 cases in the Eastern Anatolian region of Turkey. ( 26225872 )
2015
17
Cutaneous anthrax: evaluation of 28 cases in the Eastern Anatolian region of Turkey. ( 26293781 )
2015
18
Two cases of human cutaneous anthrax in Bosnia and Herzegovina, September 2014. ( 25719961 )
2015
19
Asymmetric dimethylarginine levels in patients with cutaneous anthrax: a laboratory analysis. ( 24669818 )
2014
20
Exoproteome analysis of a novel strain of Bacillus cereus implicated in disease resembling cutaneous anthrax. ( 24412723 )
2014
21
Three eyelid localized cutaneous anthrax cases. ( 24641116 )
2014
22
Optic Atrophy Secondary to Preseptal Cutaneous Anthrax: Case Report. ( 27928303 )
2014
23
Retrospective review of the case of cutaneous anthrax-malignant pustule from 1995 in 15-year old girl. ( 25848786 )
2014
24
Whole proteome analysis of mouse lymph nodes in cutaneous anthrax. ( 25329596 )
2014
25
Human cutaneous anthrax, Georgia 2010-2012. ( 24447721 )
2014
26
Serum adenosine deaminase activity in cutaneous anthrax. ( 24997584 )
2014
27
Cutaneous anthrax in a school teacher. ( 24858169 )
2014
28
Cutaneous anthrax in Southeast Anatolia of Turkey. ( 24678748 )
2014
29
Suspect vector transmission of human cutaneous anthrax during an animal outbreak in Southern Italy. ( 23808978 )
2013
30
Cutaneous anthrax resulting in renal failure with generalized tissue damage. ( 23431997 )
2013
31
Periocular cutaneous anthrax in Jimma Zone, Southwest Ethiopia: a case series. ( 23924443 )
2013
32
Fatal cutaneous anthrax in a heroin user. ( 23374534 )
2013
33
Serodiagnosis of human cutaneous anthrax in India using an indirect anti-lethal factor IgG enzyme-linked immunosorbent assay. ( 23269414 )
2013
34
Field-based PCR for rapid diagnosis of cutaneous anthrax in the deployed setting using the joint biological agent identification and diagnostic system. ( 23929060 )
2013
35
Outbreak of cutaneous anthrax in Musalimadugu village, Chittoor district, Andhra Pradesh, India, July-August 2011. ( 23103890 )
2012
36
Investigation of an outbreak of cutaneous anthrax in Banlu village, Lianyungang, China, 2012. ( 23908932 )
2012
37
Increased membrane turnover in the brain in cutaneous anthrax without central nervous system disorder: a magnetic resonance spectroscopy study. ( 22543072 )
2012
38
Naturally occurring cutaneous anthrax: antibiotic treatment and outcome. ( 22343361 )
2012
39
Three probable cases of cutaneous anthrax in autonomous province of Vojvodina, Serbia, June 2011. ( 22264812 )
2012
40
Anti-protective antigen IgG enzyme-linked immunosorbent assay for diagnosis of cutaneous anthrax in India. ( 22718130 )
2012
41
Recent outbreak of cutaneous anthrax in Bangladesh: clinico-demographic profile and treatment outcome of cases attended at Rajshahi Medical College Hospital. ( 22929128 )
2012
42
Swab protocol for rapid laboratory diagnosis of cutaneous anthrax. ( 23035192 )
2012
43
Outbreak of cutaneous anthrax in a tribal village: a clinico-epidemiological study. ( 22715553 )
2012
44
Primary cutaneous infection with Bacillus megaterium mimicking cutaneous anthrax. ( 21763557 )
2011
45
Swelling of face. Cutaneous anthrax. ( 23022827 )
2011
46
Lethal factor toxemia and anti-protective antigen antibody activity in naturally acquired cutaneous anthrax. ( 21908727 )
2011
47
The early humoral immune response to Bacillus anthracis toxins in patients infected with cutaneous anthrax. ( 21401726 )
2011
48
Clinical findings in children with cutaneous anthrax in eastern Turkey. ( 21083757 )
2010
49
Lessons learned from the investigation of a cluster of cutaneous anthrax cases in Connecticut. ( 20357605 )
2010
50
Natural exposure to cutaneous anthrax gives long-lasting T cell immunity encompassing infection-specific epitopes. ( 20208010 )
2010

Variations for Cutaneous Anthrax

Expression for Cutaneous Anthrax

Search GEO for disease gene expression data for Cutaneous Anthrax.

Pathways for Cutaneous Anthrax

Pathways related to Cutaneous Anthrax according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.92 ACOT13 GAPDH PRDX1 TKT
2 11.5 CD4 IL5 ITGA2
3 11.12 CD4 IL5 ITGA2
4 10.54 CASP1 EEF1A1 HSPD1

GO Terms for Cutaneous Anthrax

Cellular components related to Cutaneous Anthrax according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 ADA EEF1A1 HSPD1 IBSP IL5 PON1
2 extracellular matrix GO:0031012 9.46 GAPDH HSPD1 IBSP PRDX1
3 myelin sheath GO:0043209 9.02 DLD EEF1A1 HSPD1 PRDX1 TKT

Biological processes related to Cutaneous Anthrax according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 9.46 ADA CASP1 HSPD1 ITGA2
2 positive regulation of smooth muscle contraction GO:0045987 9.37 ADA ITGA2
3 response to ATP GO:0033198 9.32 CASP1 HSPD1
4 positive regulation of calcium-mediated signaling GO:0050850 9.26 ADA CD4
5 T cell activation GO:0042110 9.13 ADA CD4 HSPD1
6 positive regulation of T cell activation GO:0050870 8.8 ADA CD4 HSPD1

Sources for Cutaneous Anthrax

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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