MCID: CTN004
MIFTS: 37

Cutaneous Fibrous Histiocytoma malady

Rare diseases, Cancer diseases, Skin diseases categories

Summaries for Cutaneous Fibrous Histiocytoma

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34MalaCards
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MalaCards: Cutaneous Fibrous Histiocytoma, also known as dermatofibroma, is related to fibrous histiocytoma and dermatofibrosarcoma. An important gene associated with Cutaneous Fibrous Histiocytoma is HAVCR1 (hepatitis A virus cellular receptor 1). The compounds reticulin and hematoxylin have been mentioned in the context of this disorder. Affiliated tissues include skin and monocytes, and related mouse phenotypes are hematopoietic system and tumorigenesis.

Aliases & Classifications for Cutaneous Fibrous Histiocytoma

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9Disease Ontology, 44NIH Rare Diseases, 11DISEASES, 46Novoseek, 63UMLS, 59SNOMED-CT, 41NCIt, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Skin diseases


Aliases & Descriptions:

cutaneous fibrous histiocytoma 9 11 63
dermatofibroma 9 44 46
fibrohistiocytic tumor 9 63
benign cutaneous fibrous histiocytoma 9
dermatofibroma, no icd-o subtype 9
histiocytoma, benign fibrous 63
fibrous histiocytoma of skin 9
sclerosing angioma of skin 9
fibrohistiocytic neoplasm 9
fibrous xanthoma of skin 9
pleomorphic fibroma 9
sclerosing angioma 9
dermatofibroma nos 9


Related Diseases for Cutaneous Fibrous Histiocytoma

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18GeneCards, 19GeneDecks
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Diseases related to Cutaneous Fibrous Histiocytoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 60)
idRelated DiseaseScoreTop Affiliating Genes
1fibrous histiocytoma31.2F13A1, CD34
2dermatofibrosarcoma31.2FOXO4
3dermatofibrosarcoma protuberans30.9F13A1, MMP11, CD34
4fibroma30.9F13A1, CD34
5basal cell carcinoma30.2F13A1, MMP11, CD34
6malignant fibroxanthoma30.2F13A1, CD68
7melanoma30.0F13A1, MMP11, FOXO4, CD68, CD34
8sarcoma30.0CD34, MMP11, F13A1
9hemangiopericytoma29.9CD34, F13A1
10kaposi's sarcoma29.9F13A1, CD34
11histiocytoma10.8
12malignant skin fibrous histiocytoma10.4
13atypical lipomatous tumor10.3
14sclerosing hemangioma10.2
15aneurysm10.2
16pleomorphic liposarcoma10.1
17liposarcoma10.1
18myxofibrosarcoma10.1
19perineurioma10.1CD34
20multicentric reticulohistiocytosis10.0CD68, HAVCR1
21leiomyosarcoma10.0CD34, FOXO4
22primary hyperoxaluria10.0HAVCR1, CD68
23histiocytosis10.0CD68, F13A1
24synovitis10.0CD68, MMP11
25neurofibroma10.0F13A1, CD34
26neurilemmoma10.0CD34, F13A1
27meningioma10.0CD34, CD68
28factor v leiden thrombophilia10.0CD34, F13A1
29hemangioma10.0CD34, CD68, F13A1
30hypertrophic scars9.9
31clear cell acanthoma9.9
32hidradenitis suppurativa9.9
33granular cell tumor9.9
34ulcerative colitis9.9
35mycosis fungoides9.9
36amelanotic melanoma9.9
37necrobiosis lipoidica9.9
38down syndrome9.9
39primary pulmonary hypertension9.9
40acanthoma9.9
41chondroma9.9
42chronic lymphocytic leukemia9.9
43diabetes mellitus9.9
44eosinophilia9.9
45epithelioid sarcoma9.9
46esophageal cancer9.9
47esophagitis9.9
48fasciitis9.9
49hidradenitis9.9
50hypertension9.9

Graphical network of the top 20 diseases related to Cutaneous Fibrous Histiocytoma:



Diseases related to cutaneous fibrous histiocytoma

Symptoms for Cutaneous Fibrous Histiocytoma

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Drugs & Therapeutics for Cutaneous Fibrous Histiocytoma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Cutaneous Fibrous Histiocytoma

Search NIH Clinical Center for Cutaneous Fibrous Histiocytoma

Search CenterWatch for Cutaneous Fibrous Histiocytoma

Genetic Tests for Cutaneous Fibrous Histiocytoma

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Anatomical Context for Cutaneous Fibrous Histiocytoma

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34MalaCards
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MalaCards organs/tissues related to Cutaneous Fibrous Histiocytoma:

34
Skin, Monocytes

Animal Models for Cutaneous Fibrous Histiocytoma or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Cutaneous Fibrous Histiocytoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.5CD34, CD68, F13A1, HAVCR1
2MP:00020068.3CD34, FOXO4, MMP11

Publications for Cutaneous Fibrous Histiocytoma

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53PubMed
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Articles related to Cutaneous Fibrous Histiocytoma:

(show all 14)
idTitleAuthorsYear
1
Metastasizing "benign" cutaneous fibrous histiocytoma: a clinicopathologic analysis of 16 cases. (23426120)
2013
2
Atypical cutaneous fibrous histiocytoma: an unusual and misleading variant of fibrous histiocytoma. (22937387)
2011
3
A study of monocytic and dendritic cell markers in benign cutaneous fibrous histiocytoma (dermatofibroma). (18462367)
2008
4
A unique biphasic variant of cutaneous fibrous histiocytoma with a storiform pattern and intralesional pigmented melanocytes: "storiform melano-fibrous histiocytoma". (18474466)
2008
5
Clonal analysis of cutaneous fibrous histiocytoma (dermatofibroma). (12139632)
2002
6
Aneurysmal fibrous histiocytoma: an unusual variant of cutaneous fibrous histiocytoma. (10461644)
1999
7
Recurring atypical ("pseudosarcomatous") cutaneous fibrous histiocytoma. (9649666)
1998
8
Cutaneous fibrous histiocytoma. (9158319)
1997
9
Cutaneous fibrous histiocytoma with osteoclast-like giant cells. (8863988)
1996
10
Cellular benign fibrous histiocytoma. Clinicopathologic analysis of 74 cases of a distinctive variant of cutaneous fibrous histiocytoma with frequent recurrence. (8017561)
1994
11
Palisading cutaneous fibrous histiocytoma. An immunohistochemical study demonstrating differentiation from dermal dendrocytes. (8311187)
1993
12
Palisading cutaneous fibrous histiocytoma. (3029199)
1986
13
Atypical cutaneous fibrous histiocytoma. (3028197)
1986
14
Atypical, cutaneous fibrous histiocytoma with early metastasis. (3012378)
1986

Variations for Cutaneous Fibrous Histiocytoma

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Expression for genes affiliated with Cutaneous Fibrous Histiocytoma

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cutaneous Fibrous Histiocytoma

Search GEO for disease gene expression data for Cutaneous Fibrous Histiocytoma.

Pathways for genes affiliated with Cutaneous Fibrous Histiocytoma

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Compounds for genes affiliated with Cutaneous Fibrous Histiocytoma

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46Novoseek, 30IUPHAR, 62Tocris Bioscience, 25HMDB, 12DrugBank
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Compounds related to Cutaneous Fibrous Histiocytoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1reticulin469.6F13A1, CD34
2hematoxylin469.5F13A1, CD34
3silver469.2CD34, F13A1
4vegf468.7F13A1, MMP11, CD34
5progesterone46 30 62 25 1212.6F13A1, MMP11, CD34
6paraffin468.2CD34, CD68, MMP11, F13A1

GO Terms for genes affiliated with Cutaneous Fibrous Histiocytoma

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Products for genes affiliated with Cutaneous Fibrous Histiocytoma

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Sources for Cutaneous Fibrous Histiocytoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet