MCID: CTN004
MIFTS: 38

Cutaneous Fibrous Histiocytoma malady

Rare diseases, Cancer diseases, Skin diseases categories
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Summaries for Cutaneous Fibrous Histiocytoma

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MalaCards based summary: Cutaneous Fibrous Histiocytoma, also known as dermatofibroma, is related to fibrous histiocytoma and dermatofibrosarcoma protuberans. An important gene associated with Cutaneous Fibrous Histiocytoma is HAVCR1 (hepatitis A virus cellular receptor 1). The compounds reticulin and hematoxylin have been mentioned in the context of this disorder. Affiliated tissues include skin and monocytes, and related mouse phenotypes are hematopoietic system and tumorigenesis.

Aliases & Classifications for Cutaneous Fibrous Histiocytoma

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Cutaneous Fibrous Histiocytoma, Aliases & Descriptions:

Name: Cutaneous Fibrous Histiocytoma 8 10 62
Dermatofibroma 8 42 44
Benign Cutaneous Fibrous Histiocytoma 8 62
Fibrohistiocytic Neoplasm 8 62
Fibrous Xanthoma of Skin 8 62
Fibrohistiocytic Tumor 8 62
Dermatofibroma, No Icd-O Subtype 8
 
Histiocytoma, Benign Fibrous 62
Fibrous Histiocytoma of Skin 8
Sclerosing Angioma of Skin 8
Pleomorphic Fibroma 8
Dermatofibroma Nos 8
Sclerosing Angioma 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Skin diseases


Related Diseases for Cutaneous Fibrous Histiocytoma

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Diseases related to Cutaneous Fibrous Histiocytoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 65)
idRelated DiseaseScoreTop Affiliating Genes
1fibrous histiocytoma31.3F13A1, CD34
2dermatofibrosarcoma protuberans31.1FOXO4
3fibroma30.9F13A1, CD34
4malignant fibroxanthoma30.4F13A1, CD68
5basal cell carcinoma29.9F13A1, MMP11, CD34
6hemangiopericytoma29.9CD34, F13A1
7kaposi's sarcoma29.8F13A1, CD34
8sarcoma29.7CD34, MMP11, F13A1
9melanoma29.3F13A1, MMP11, FOXO4, CD68, CD34
10histiocytoma10.8
11malignant skin fibrous histiocytoma10.4
12perineurioma10.4CD34
13atypical lipomatous tumor10.3
14sclerosing hemangioma10.2
15aneurysm10.2
16histiocytosis10.2CD68, HAVCR1
17multicentric reticulohistiocytosis10.2CD68, HAVCR1
18pleomorphic liposarcoma10.2
19liposarcoma10.2
20myxofibrosarcoma10.2
21leiomyosarcoma10.1CD34, FOXO4
22keratosis10.1
23seborrheic keratosis10.1
24primary hyperoxaluria10.0HAVCR1, CD68
25langerhans-cell histiocytosis10.0CD68, F13A1
26synovitis10.0CD68, MMP11
27neurofibroma10.0F13A1, CD34
28hypertrophic scars9.9
29chronic lymphocytic leukemia9.9
30diabetes mellitus9.9
31esophageal cancer9.9
32hypertension9.9
33keloids9.9
34leukemia9.9
35melanoma metastasis9.9
36mycosis fungoides9.9
37pulmonary hypertension9.9
38ulcerative colitis9.9
39hidradenitis suppurativa9.9
40granular cell tumor9.9
41down syndrome9.9
42primary pulmonary hypertension9.9
43clear cell acanthoma9.9
44amelanotic melanoma9.9
45folliculitis9.9
46necrobiosis lipoidica9.9
47acanthoma9.9
48chondroma9.9
49colitis9.9
50eosinophilia9.9

Graphical network of the top 20 diseases related to Cutaneous Fibrous Histiocytoma:



Diseases related to cutaneous fibrous histiocytoma

Symptoms for Cutaneous Fibrous Histiocytoma

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Drugs & Therapeutics for Cutaneous Fibrous Histiocytoma

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Drug clinical trials:

Search ClinicalTrials for Cutaneous Fibrous Histiocytoma

Search NIH Clinical Center for Cutaneous Fibrous Histiocytoma

Genetic Tests for Cutaneous Fibrous Histiocytoma

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Anatomical Context for Cutaneous Fibrous Histiocytoma

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MalaCards organs/tissues related to Cutaneous Fibrous Histiocytoma:

32
Skin, Monocytes

Animal Models for Cutaneous Fibrous Histiocytoma or affiliated genes

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MGI Mouse Phenotypes related to Cutaneous Fibrous Histiocytoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.5CD34, CD68, F13A1, HAVCR1
2MP:00020068.3CD34, FOXO4, MMP11

Publications for Cutaneous Fibrous Histiocytoma

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Articles related to Cutaneous Fibrous Histiocytoma:

(show all 15)
idTitleAuthorsYear
1
Metastasizing "benign" cutaneous fibrous histiocytoma: a clinicopathologic analysis of 16 cases. (23426120)
2013
2
Atypical cutaneous fibrous histiocytoma: an unusual and misleading variant of fibrous histiocytoma. (22937387)
2011
3
A study of monocytic and dendritic cell markers in benign cutaneous fibrous histiocytoma (dermatofibroma). (18462367)
2008
4
A unique biphasic variant of cutaneous fibrous histiocytoma with a storiform pattern and intralesional pigmented melanocytes: "storiform melano-fibrous histiocytoma". (18474466)
2008
5
The value of immunohistochemistry in atypical cutaneous fibrous histiocytoma. (15365367)
2004
6
Clonal analysis of cutaneous fibrous histiocytoma (dermatofibroma). (12139632)
2002
7
Aneurysmal fibrous histiocytoma: an unusual variant of cutaneous fibrous histiocytoma. (10461644)
1999
8
Recurring atypical ("pseudosarcomatous") cutaneous fibrous histiocytoma. (9649666)
1998
9
Cutaneous fibrous histiocytoma. (9158319)
1997
10
Cutaneous fibrous histiocytoma with osteoclast-like giant cells. (8863988)
1996
11
Cellular benign fibrous histiocytoma. Clinicopathologic analysis of 74 cases of a distinctive variant of cutaneous fibrous histiocytoma with frequent recurrence. (8017561)
1994
12
Palisading cutaneous fibrous histiocytoma. An immunohistochemical study demonstrating differentiation from dermal dendrocytes. (8311187)
1993
13
Palisading cutaneous fibrous histiocytoma. (3029199)
1986
14
Atypical cutaneous fibrous histiocytoma. (3028197)
1986
15
Atypical, cutaneous fibrous histiocytoma with early metastasis. (3012378)
1986

Variations for Cutaneous Fibrous Histiocytoma

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Expression for genes affiliated with Cutaneous Fibrous Histiocytoma

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Expression patterns in normal tissues for genes affiliated with Cutaneous Fibrous Histiocytoma

Search GEO for disease gene expression data for Cutaneous Fibrous Histiocytoma.

Pathways for genes affiliated with Cutaneous Fibrous Histiocytoma

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Compounds for genes affiliated with Cutaneous Fibrous Histiocytoma

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Sources:
44Novoseek, 28IUPHAR, 61Tocris Bioscience, 24HMDB, 11DrugBank
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Compounds related to Cutaneous Fibrous Histiocytoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1reticulin449.6F13A1, CD34
2hematoxylin449.5F13A1, CD34
3silver449.2CD34, F13A1
4vegf448.7F13A1, MMP11, CD34
5progesterone44 28 61 24 1112.6F13A1, MMP11, CD34
6paraffin448.2CD34, CD68, MMP11, F13A1

GO Terms for genes affiliated with Cutaneous Fibrous Histiocytoma

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Products for genes affiliated with Cutaneous Fibrous Histiocytoma

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  • Antibodies
  • Proteins
  • Lysates

Sources for Cutaneous Fibrous Histiocytoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet