MCID: CTN004
MIFTS: 31

Cutaneous Fibrous Histiocytoma malady

Rare diseases, Skin diseases, Cancer diseases categories

Summaries for Cutaneous Fibrous Histiocytoma

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MalaCards based summary: Cutaneous Fibrous Histiocytoma, also known as dermatofibroma, is related to fibrous histiocytoma and dermatofibrosarcoma protuberans. An important gene associated with Cutaneous Fibrous Histiocytoma is HAVCR1 (hepatitis A virus cellular receptor 1). The compounds reticulin and hematoxylin have been mentioned in the context of this disorder. Affiliated tissues include skin and monocytes, and related mouse phenotypes are hematopoietic system and tumorigenesis.

Aliases & Classifications for Cutaneous Fibrous Histiocytoma

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Cutaneous Fibrous Histiocytoma, Aliases & Descriptions:

Name: Cutaneous Fibrous Histiocytoma 9 11 60
Dermatofibroma 9 41 43
Fibrohistiocytic Tumor 9 60
Benign Cutaneous Fibrous Histiocytoma 9
Dermatofibroma, No Icd-O Subtype 9
Fibrous Histiocytoma of Skin 9
 
Sclerosing Angioma of Skin 9
Fibrohistiocytic Neoplasm 9
Fibrous Xanthoma of Skin 9
Pleomorphic Fibroma 9
Dermatofibroma Nos 9
Sclerosing Angioma 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Skin diseases


Related Diseases for Cutaneous Fibrous Histiocytoma

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Diseases related to Cutaneous Fibrous Histiocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 59)
idRelated DiseaseScoreTop Affiliating Genes
1fibrous histiocytoma31.3F13A1, CD34
2dermatofibrosarcoma protuberans31.1FOXO4
3malignant fibroxanthoma30.2CD68, F13A1
4hemangiopericytoma29.9CD34, F13A1
5basal cell carcinoma29.9CD34, MMP11, F13A1
6fibroma29.9F13A1, CD34
7sarcoma29.7CD34, MMP11, F13A1
8melanoma29.3MMP11, F13A1, FOXO4, CD34, CD68
9histiocytoma10.8
10malignant skin fibrous histiocytoma10.4
11perineurioma10.4CD34
12classic kaposi sarcoma10.3CD34
13atypical lipomatous tumor10.3
14sclerosing hemangioma10.2
15aneurysm10.2
16histiocytosis10.2HAVCR1, CD68
17multicentric reticulohistiocytosis10.2HAVCR1, CD68
18pleomorphic liposarcoma10.2
19liposarcoma10.2
20myxofibrosarcoma10.2
21leiomyosarcoma10.1CD34, FOXO4
22keratosis10.1
23kidney disease10.0HAVCR1, CD68
24langerhans-cell histiocytosis10.0CD68, F13A1
25synovitis10.0MMP11, CD68
26neurofibroma10.0CD34, F13A1
27esophageal cancer10.0
28pulmonary hypertension10.0
29chronic lymphocytic leukemia10.0
30leukemia10.0
31melanoma metastasis10.0
32ulcerative colitis10.0
33clear cell acanthoma10.0
34hidradenitis suppurativa10.0
35granular cell tumor10.0
36amelanotic melanoma10.0
37folliculitis10.0
38necrobiosis lipoidica10.0
39down syndrome10.0
40acanthoma10.0
41chondroma10.0
42colitis10.0
43eosinophilia10.0
44epithelioid sarcoma10.0
45esophagitis10.0
46fasciitis10.0
47hidradenitis10.0
48smallpox10.0
49hemangioendothelioma10.0
50spitz nevus10.0

Graphical network of the top 20 diseases related to Cutaneous Fibrous Histiocytoma:



Diseases related to cutaneous fibrous histiocytoma

Symptoms for Cutaneous Fibrous Histiocytoma

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Drugs & Therapeutics for Cutaneous Fibrous Histiocytoma

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Drug clinical trials:

Search ClinicalTrials for Cutaneous Fibrous Histiocytoma

Search NIH Clinical Center for Cutaneous Fibrous Histiocytoma

Genetic Tests for Cutaneous Fibrous Histiocytoma

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Anatomical Context for Cutaneous Fibrous Histiocytoma

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MalaCards organs/tissues related to Cutaneous Fibrous Histiocytoma:

31
Skin, Monocytes

Animal Models for Cutaneous Fibrous Histiocytoma or affiliated genes

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MGI Mouse Phenotypes related to Cutaneous Fibrous Histiocytoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.5CD34, CD68, F13A1, HAVCR1
2MP:00020068.3CD34, FOXO4, MMP11

Publications for Cutaneous Fibrous Histiocytoma

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Articles related to Cutaneous Fibrous Histiocytoma:

(show all 15)
idTitleAuthorsYear
1
Metastasizing "benign" cutaneous fibrous histiocytoma: a clinicopathologic analysis of 16 cases. (23426120)
2013
2
Atypical cutaneous fibrous histiocytoma: an unusual and misleading variant of fibrous histiocytoma. (22937387)
2011
3
A study of monocytic and dendritic cell markers in benign cutaneous fibrous histiocytoma (dermatofibroma). (18462367)
2008
4
A unique biphasic variant of cutaneous fibrous histiocytoma with a storiform pattern and intralesional pigmented melanocytes: "storiform melano-fibrous histiocytoma". (18474466)
2008
5
The value of immunohistochemistry in atypical cutaneous fibrous histiocytoma. (15365367)
2004
6
Clonal analysis of cutaneous fibrous histiocytoma (dermatofibroma). (12139632)
2002
7
Aneurysmal fibrous histiocytoma: an unusual variant of cutaneous fibrous histiocytoma. (10461644)
1999
8
Recurring atypical ("pseudosarcomatous") cutaneous fibrous histiocytoma. (9649666)
1998
9
Cutaneous fibrous histiocytoma. (9158319)
1997
10
Cutaneous fibrous histiocytoma with osteoclast-like giant cells. (8863988)
1996
11
Cellular benign fibrous histiocytoma. Clinicopathologic analysis of 74 cases of a distinctive variant of cutaneous fibrous histiocytoma with frequent recurrence. (8017561)
1994
12
Palisading cutaneous fibrous histiocytoma. An immunohistochemical study demonstrating differentiation from dermal dendrocytes. (8311187)
1993
13
Palisading cutaneous fibrous histiocytoma. (3029199)
1986
14
Atypical cutaneous fibrous histiocytoma. (3028197)
1986
15
Atypical, cutaneous fibrous histiocytoma with early metastasis. (3012378)
1986

Variations for Cutaneous Fibrous Histiocytoma

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Expression for genes affiliated with Cutaneous Fibrous Histiocytoma

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Search GEO for disease gene expression data for Cutaneous Fibrous Histiocytoma.

Pathways for genes affiliated with Cutaneous Fibrous Histiocytoma

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Compounds for genes affiliated with Cutaneous Fibrous Histiocytoma

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Sources:
43Novoseek, 28IUPHAR, 59Tocris Bioscience, 24HMDB, 12DrugBank
See all sources

Compounds related to Cutaneous Fibrous Histiocytoma according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1reticulin439.6F13A1, CD34
2hematoxylin439.5F13A1, CD34
3silver439.2CD34, F13A1
4vegf438.7F13A1, MMP11, CD34
5progesterone43 28 59 24 1212.6F13A1, MMP11, CD34
6paraffin438.2CD34, CD68, MMP11, F13A1

GO Terms for genes affiliated with Cutaneous Fibrous Histiocytoma

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Products for genes affiliated with Cutaneous Fibrous Histiocytoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Cutaneous Fibrous Histiocytoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet