MCID: CYC008
MIFTS: 28

Cyclic Vomiting Syndrome malady

Genetic diseases, Rare diseases categories

Aliases & Classifications for Cyclic Vomiting Syndrome

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Cyclic Vomiting Syndrome, Aliases & Descriptions:

Name: Cyclic Vomiting Syndrome 41 21
Cyclical Vomiting Syndrome 21 60
Abdominal Migraine 21 60
Cvs 41 21
 
Familial Cyclic Vomiting Syndrome 41
Cyclical Vomiting 21
Periodic Vomiting 21


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases


Summaries for Cyclic Vomiting Syndrome

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NIH Rare Diseases:41 Cyclic vomiting syndrome (cvs) is a condition characterized by recurrent episodes of severe nausea and vomiting. episodes can last for hours or days. each episode is usually similar to previous ones. other symptoms may include physical exhaustion, pale skin, abdominal pain, diarrhea, headache, and/or fever. cvs can begin at any age but is most often diagnosed in children around 5 years of age. the underlying cause of cvs is not known, but children who suffer from migraines are more likely to develop cvs. treatment aims to control symptoms and may include anti-nausea drugs, sedatives, medications that suppress stomach acid, and/or antidepressants. last updated: 11/12/2014

MalaCards based summary: Cyclic Vomiting Syndrome, also known as cyclical vomiting syndrome, is related to migraine and headache. An important gene associated with Cyclic Vomiting Syndrome is MT-TL1 (mitochondrially encoded tRNA leucine 1 (UUA/G)), and among its related pathways are CREB Pathway and SIDS Susceptibility Pathways. The compounds dexamethasone and norepinephrine have been mentioned in the context of this disorder. Affiliated tissues include skin, brain and heart.

Genetics Home Reference:21 Cyclic vomiting syndrome is a disorder that causes recurrent episodes of nausea, vomiting, and tiredness (lethargy). This condition is diagnosed most often in young children, but it can affect people of any age.

Wikipedia:63 Cyclic vomiting syndrome (US English) or cyclical vomiting syndrome (UK English) (CVS) is a chronic... more...

Related Diseases for Cyclic Vomiting Syndrome

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Graphical network of the top 20 diseases related to Cyclic Vomiting Syndrome:



Diseases related to cyclic vomiting syndrome

Symptoms for Cyclic Vomiting Syndrome

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Drugs & Therapeutics for Cyclic Vomiting Syndrome

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Drug clinical trials:

Search ClinicalTrials for Cyclic Vomiting Syndrome

Search NIH Clinical Center for Cyclic Vomiting Syndrome

Genetic Tests for Cyclic Vomiting Syndrome

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Anatomical Context for Cyclic Vomiting Syndrome

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MalaCards organs/tissues related to Cyclic Vomiting Syndrome:

31
Skin, Brain, Heart, Testes

Animal Models for Cyclic Vomiting Syndrome or affiliated genes

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Publications for Cyclic Vomiting Syndrome

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Articles related to Cyclic Vomiting Syndrome:

(show top 50)    (show all 139)
idTitleAuthorsYear
1
Inappropriate arginine vasopressin levels and hyponatremia associated with cyclic vomiting syndrome. (25759635)
2015
2
Pediatric Emergency Update: Cyclic Vomiting Syndrome. (25814094)
2015
3
Injectable sumatriptan for cyclic vomiting syndrome in adults: a case series. (25168483)
2014
4
Mitochondrial disorder caused Charles Darwin's cyclic vomiting syndrome. (24453499)
2014
5
Short- and long-term outcomes of children with cyclic vomiting syndrome. (25632624)
2014
6
Cyclic vomiting syndrome: A common, underrecognized disorder. (24170626)
2013
7
Rapid Response to Mirtazapine in Cyclic Vomiting Syndrome Refractory to Conventional Prokinetics. (24360530)
2013
8
Cyclic vomiting syndrome masking a fatal metabolic disease. (23052622)
2013
9
From heave to leave: understanding cyclic vomiting syndrome. (24304524)
2013
10
Cyclic Vomiting Syndrome (CVS): is there a difference based on onset of symptoms--pediatric versus adult? (22639867)
2012
11
Cyclic vomiting syndrome in 28 patients: demographics, features and outcomes. (22617361)
2012
12
Cyclic vomiting syndrome and functional vomiting in adults: association with cannabinoid use in males. (21951771)
2012
13
Cyclic vomiting syndrome: a physiological response to a pathologic substrate? (21138501)
2011
14
A case of cyclic vomiting syndrome responding to gonadotropin-releasing hormone analogue. (20535330)
2010
15
Adult cyclic vomiting syndrome successfully treated with intranasal sumatriptan. (19911235)
2010
16
Treatment of cyclic vomiting syndrome with co-enzyme Q10 and amitriptyline, a retrospective study. (20109231)
2010
17
A comparison of dysautonomias comorbid with cyclic vomiting syndrome and with migraine. (20111731)
2009
18
Two cases of cyclic vomiting syndrome in systemic autoimmune conditions: SLE and autoimmune hepatitis. (19433469)
2009
19
Cyclic vomiting syndrome: what does it mean? (19824494)
2009
20
Successful treatment with sumatriptan in a case with cyclic vomiting syndrome combined with 18q- syndrome. (19794103)
2009
21
An adult case of cyclic vomiting syndrome successfully responding to valproic acid. (18458864)
2008
22
Cyclic vomiting syndrome in children: experience with 181 cases from southern Iran. (17465476)
2007
23
An oral complication in a patient with cyclic vomiting syndrome: a case report and review. (17134074)
2006
24
An adult case of cyclic vomiting syndrome in which tricyclic antidepressant was effective]. (17260810)
2006
25
Dihydroergotamine-associated intestinal ischemia in a child with cyclic vomiting syndrome. (16707983)
2006
26
Maternal inheritance in cyclic vomiting syndrome. (15643622)
2005
27
The clinical profile of cyclic vomiting syndrome in a regional hospital, Saudi Arabia. (16512460)
2005
28
Mitochondrial DNA control region sequence variation in migraine headache and cyclic vomiting syndrome. (15368478)
2004
29
Gastric emptying time in cyclic vomiting syndrome in children. (15745390)
2004
30
Cyclic vomiting syndrome: anticipatory stress response in migraine? (14979896)
2004
31
Cyclic vomiting syndrome: a brain-gut disorder. (14562585)
2003
32
Cyclic vomiting syndrome, migraine, and epilepsy: a common underlying disorder? (12656714)
2003
33
Familial cyclic vomiting syndrome. (12230597)
2002
34
Cyclic vomiting syndrome in Thai children. (12403255)
2002
35
Cyclic Vomiting Syndrome. (11096600)
2000
36
Cyclic vomiting syndrome and food allergy/intolerance in seven children: a possible association. (10834522)
2000
37
Psychological and social characteristics and precipitants of vomiting in children with cyclic vomiting syndrome. (10490034)
1999
38
Electrogastrography in cyclic vomiting syndrome. (10490042)
1999
39
Mitochondrial fatty acid oxidation disorders and cyclic vomiting syndrome. (10490047)
1999
40
Cyclic vomiting syndrome and migraine. (10228283)
1999
41
Cyclic vomiting syndrome in adults: clinical features and response to tricyclic antidepressants. (10520833)
1999
42
Cyclic vomiting syndrome: timing, targets, and treatment--a basic science perspective. (10490037)
1999
43
Evaluation of neurocardiac signals in pediatric patients with cyclic vomiting syndrome through power spectral analysis of heart rate variability. (10484804)
1999
44
Cyclic vomiting syndrome and mitochondrial DNA mutations. (9357417)
1997
45
Cyclic vomiting syndrome: a paroxismal disorder of brain-gut interaction. (9285854)
1997
46
Management of cyclic vomiting syndrome. (8708870)
1995
47
Cyclic vomiting syndrome. Introduction. (8708858)
1995
48
Prophylactic therapy in cyclic vomiting syndrome. (8708871)
1995
49
The relationship between cyclic vomiting syndrome and abdominal migraine. (8708867)
1995
50
Cyclic vomiting syndrome: a pediatric Rorschach test. (8145085)
1993

Variations for Cyclic Vomiting Syndrome

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Clinvar genetic disease variations for Cyclic Vomiting Syndrome:

6
id Gene Variation Type Significance SNP ID Assembly Location
1MT-TL1m.3243A> Gsingle nucleotide variantPathogenicrs199474657GRCh37Chr MT, 3243: 3243

Expression for genes affiliated with Cyclic Vomiting Syndrome

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Search GEO for disease gene expression data for Cyclic Vomiting Syndrome.

Pathways for genes affiliated with Cyclic Vomiting Syndrome

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Pathways related to Cyclic Vomiting Syndrome according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.0IL6, HTR3A
29.0IL6, HTR3A

Compounds for genes affiliated with Cyclic Vomiting Syndrome

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Sources:
43Novoseek, 49PharmGKB, 28IUPHAR, 12DrugBank, 24HMDB
See all sources

Compounds related to Cyclic Vomiting Syndrome according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1dexamethasone43 49 28 1212.0IL6, HTR3A
2norepinephrine43 24 1210.9IL6, HTR3A
3histamine43 28 2410.7IL6, HTR3A

GO Terms for genes affiliated with Cyclic Vomiting Syndrome

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Products for genes affiliated with Cyclic Vomiting Syndrome

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Sources for Cyclic Vomiting Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet