CVS
MCID: CYC008
MIFTS: 33

Cyclic Vomiting Syndrome (CVS) malady

Genetic diseases, Rare diseases categories

Summaries for Cyclic Vomiting Syndrome

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44NIH Rare Diseases, 22Genetics Home Reference, 66Wikipedia, 34MalaCards
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NIH Rare Diseases:44 Cyclic vomiting syndrome (cvs) is a disorder with recurrent episodes of severe nausea and vomiting interspersed with symptom free periods. the cycles of severe nausea and vomiting can last for hours or even days. each episode is similar to the previous ones. the episodes tend to start at about the same time of day, last the same length of time, and present the same symptoms at the same level of intensity. although cyclic vomiting syndrome can begin at any age in children and adults, it usually starts between the ages of 3 and 7. although the underlying cause of cyclic vomiting syndrome is not known, some cases appear to be to be linked to migraines. treatment with migraine medications often helps.         last updated: 12/19/2013

MalaCards: Cyclic Vomiting Syndrome, also known as cyclical vomiting syndrome, is related to leukemia and migraine. An important gene associated with Cyclic Vomiting Syndrome is HTR3A (5-hydroxytryptamine (serotonin) receptor 3A, ionotropic), and among its related pathways are CREB Pathway and SIDS Susceptibility Pathways. The compounds dexamethasone and norepinephrine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and heart, and related mouse phenotype renal/urinary system.

Genetics Home Reference:22 Cyclic vomiting syndrome is a disorder that causes recurrent episodes of nausea, vomiting, and tiredness (lethargy). This condition is diagnosed most often in young children, but it can affect people of any age.

Wikipedia:66 Cyclic vomiting syndrome (US English) or cyclical vomiting syndrome (UK English) (CVS) is a chronic... more...

Aliases & Classifications for Cyclic Vomiting Syndrome

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44NIH Rare Diseases, 22Genetics Home Reference, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases


Aliases & Descriptions:

cyclic vomiting syndrome 44 22
cyclical vomiting syndrome 22 63
cvs 44 22
familial cyclic vomiting syndrome 44
abdominal migraine 22
cyclical vomiting 22
periodic vomiting 22


Related Diseases for Cyclic Vomiting Syndrome

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Cyclic Vomiting Syndrome:



Diseases related to cyclic vomiting syndrome

Symptoms for Cyclic Vomiting Syndrome

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Drugs & Therapeutics for Cyclic Vomiting Syndrome

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Cyclic Vomiting Syndrome

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Anatomical Context for Cyclic Vomiting Syndrome

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34MalaCards
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MalaCards organs/tissues related to Cyclic Vomiting Syndrome:

34
Brain, Testes, Heart

Animal Models for Cyclic Vomiting Syndrome or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Cyclic Vomiting Syndrome:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053679.0IL6, HTR3A

Publications for Cyclic Vomiting Syndrome

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53PubMed
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Articles related to Cyclic Vomiting Syndrome:

(show top 50)    (show all 121)
idTitleAuthorsYear
1
Cyclic vomiting syndrome: A common, underrecognized disorder. (24170626)
2013
2
Rapid Response to Mirtazapine in Cyclic Vomiting Syndrome Refractory to Conventional Prokinetics. (24360530)
2013
3
Cyclic vomiting syndrome masking a fatal metabolic disease. (23052622)
2013
4
From heave to leave: understanding cyclic vomiting syndrome. (24304524)
2013
5
Cyclic Vomiting Syndrome (CVS): is there a difference based on onset of symptoms--pediatric versus adult? (22639867)
2012
6
Cyclic vomiting syndrome in 28 patients: demographics, features and outcomes. (22617361)
2012
7
Cyclic vomiting syndrome and functional vomiting in adults: association with cannabinoid use in males. (21951771)
2012
8
Cyclic vomiting syndrome: a physiological response to a pathologic substrate? (21138501)
2011
9
Sumatriptan as a treatment for cyclic vomiting syndrome: a clinical trial. (21147834)
2011
10
A case of cyclic vomiting syndrome responding to gonadotropin-releasing hormone analogue. (20535330)
2010
11
Adult cyclic vomiting syndrome successfully treated with intranasal sumatriptan. (19911235)
2010
12
Treatment of cyclic vomiting syndrome with co-enzyme Q10 and amitriptyline, a retrospective study. (20109231)
2010
13
Autonomic nerve function in adults with cyclic vomiting syndrome: a prospective study. (20667005)
2010
14
Efficacy of tricyclic antidepressant therapy in adults with cyclic vomiting syndrome: a two-year follow-up study. (20027010)
2010
15
A comparison of dysautonomias comorbid with cyclic vomiting syndrome and with migraine. (20111731)
2009
16
Two cases of cyclic vomiting syndrome in systemic autoimmune conditions: SLE and autoimmune hepatitis. (19433469)
2009
17
Cyclic vomiting syndrome: what does it mean? (19824494)
2009
18
Successful treatment with sumatriptan in a case with cyclic vomiting syndrome combined with 18q- syndrome. (19794103)
2009
19
An adult case of cyclic vomiting syndrome successfully responding to valproic acid. (18458864)
2008
20
Cyclic vomiting syndrome in children: experience with 181 cases from southern Iran. (17465476)
2007
21
An oral complication in a patient with cyclic vomiting syndrome: a case report and review. (17134074)
2006
22
An adult case of cyclic vomiting syndrome in which tricyclic antidepressant was effective]. (17260810)
2006
23
Dihydroergotamine-associated intestinal ischemia in a child with cyclic vomiting syndrome. (16707983)
2006
24
Maternal inheritance in cyclic vomiting syndrome. (15643622)
2005
25
The clinical profile of cyclic vomiting syndrome in a regional hospital, Saudi Arabia. (16512460)
2005
26
Mitochondrial DNA control region sequence variation in migraine headache and cyclic vomiting syndrome. (15368478)
2004
27
Gastric emptying time in cyclic vomiting syndrome in children. (15745390)
2004
28
Cyclic vomiting syndrome: anticipatory stress response in migraine? (14979896)
2004
29
Cyclic vomiting syndrome: a brain-gut disorder. (14562585)
2003
30
Cyclic vomiting syndrome, migraine, and epilepsy: a common underlying disorder? (12656714)
2003
31
Familial cyclic vomiting syndrome. (12230597)
2002
32
Cyclic vomiting syndrome in Thai children. (12403255)
2002
33
Cyclic vomiting syndrome: in vitro nitric oxide and interleukin-6 release by esophageal and gastric mucosa. (11330420)
2001
34
Cyclic Vomiting Syndrome. (11096600)
2000
35
Cyclic vomiting syndrome and food allergy/intolerance in seven children: a possible association. (10834522)
2000
36
Psychological and social characteristics and precipitants of vomiting in children with cyclic vomiting syndrome. (10490034)
1999
37
Electrogastrography in cyclic vomiting syndrome. (10490042)
1999
38
Mitochondrial fatty acid oxidation disorders and cyclic vomiting syndrome. (10490047)
1999
39
Cyclic vomiting syndrome and migraine. (10228283)
1999
40
Cyclic vomiting syndrome in adults: clinical features and response to tricyclic antidepressants. (10520833)
1999
41
Cyclic vomiting syndrome: timing, targets, and treatment--a basic science perspective. (10490037)
1999
42
Evaluation of neurocardiac signals in pediatric patients with cyclic vomiting syndrome through power spectral analysis of heart rate variability. (10484804)
1999
43
Cyclic vomiting syndrome in South-East Asian children. (9928652)
1998
44
Cyclic vomiting syndrome and mitochondrial DNA mutations. (9357417)
1997
45
Cyclic vomiting syndrome: a paroxismal disorder of brain-gut interaction. (9285854)
1997
46
Management of cyclic vomiting syndrome. (8708870)
1995
47
Cyclic vomiting syndrome. Introduction. (8708858)
1995
48
Prophylactic therapy in cyclic vomiting syndrome. (8708871)
1995
49
The relationship between cyclic vomiting syndrome and abdominal migraine. (8708867)
1995
50
Cyclic vomiting syndrome: a pediatric Rorschach test. (8145085)
1993

Variations for Cyclic Vomiting Syndrome

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1 National Center for Biotechnology Information (Clinvar)
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Clinvar genetic disease variations for Cyclic Vomiting Syndrome:

1
id Gene Name Type Significance SNP ID Assembly Location
1MT-TL1m.3243A> Gsingle nucleotide variantPathogenicrs199474657GRCh37Chr MT, 3243: 3243

Expression for genes affiliated with Cyclic Vomiting Syndrome

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cyclic Vomiting Syndrome

Search GEO for disease gene expression data for Cyclic Vomiting Syndrome.

Pathways for genes affiliated with Cyclic Vomiting Syndrome

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51PathCards, 54QIAGEN, 39NCBI BioSystems Database
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Pathways related to Cyclic Vomiting Syndrome according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.0IL6, HTR3A
29.0IL6, HTR3A

Compounds for genes affiliated with Cyclic Vomiting Syndrome

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46Novoseek, 52PharmGKB, 30IUPHAR, 12DrugBank, 25HMDB
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Compounds related to Cyclic Vomiting Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1dexamethasone46 52 30 1212.0IL6, HTR3A
2norepinephrine46 25 1210.9IL6, HTR3A
3histamine46 30 2510.7IL6, HTR3A

GO Terms for genes affiliated with Cyclic Vomiting Syndrome

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Products for genes affiliated with Cyclic Vomiting Syndrome

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  • Antibodies
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  • Lysates
  • Antibodies

Sources for Cyclic Vomiting Syndrome

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet