MCID: CYS014
MIFTS: 52

Cystadenocarcinoma malady

Summaries for Cystadenocarcinoma

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, in which cystic accumulations of retained secretions are formed.

MalaCards: Cystadenocarcinoma, also known as cystadenocarcinoma nos, is related to mucinous cystadenocarcinoma and ovarian mucinous cystadenocarcinoma. An important gene associated with Cystadenocarcinoma is FSHR (follicle stimulating hormone receptor), and among its related pathways are Ovarian Infertility Genes and O-linked glycosylation of mucins. The compounds estrogen and butyrate have been mentioned in the context of this disorder. Affiliated tissues include ovary, pancreas and appendix, and related mouse phenotypes are homeostasis/metabolism and tumorigenesis.

Wikipedia:63 Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from... more...

Aliases & Classifications for Cystadenocarcinoma

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8Disease Ontology, 44Novoseek, 60UMLS, 39NCIt, 34MeSH, 56SNOMED-CT
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Aliases & Descriptions:

cystadenocarcinoma 8 44 60
cystadenocarcinoma nos 8


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Disease Ontology8 DOID:3111
NCIt39 C2971
SNOMED-CT56 21008007, 189681005
MeSH34 D003536

Related Diseases for Cystadenocarcinoma

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17GeneCards, 18GeneDecks
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Diseases related to Cystadenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 201)
idRelated DiseaseScoreTop Affiliating Genes
1mucinous cystadenocarcinoma31.5CEACAM7, MUC1, MUC16, CEACAM3
2ovarian mucinous cystadenocarcinoma31.0LMX1A, FSHR
3cystadenoma30.9FSHR, CEACAM3
4ovarian serous cystadenocarcinoma30.9ZNF217, USP2, USP14, UBE4A, MUC16
5peritonitis30.6MUC16
6pseudomyxoma peritonei30.5MUC2
7adenocarcinoma30.4CEACAM3, GAST, AKT1, MUC2, MUC16, MUC1
8sarcoma30.3MUC1, VIM
9giant cell tumor30.3CEACAM3, VIM, MUC1
10papillary carcinoma30.2MUC1, MUC16, CEACAM3, PGR, MUC2
11papillary adenocarcinoma30.1MUC2, MUC16, MUC1
12ovarian cancer30.1ESR2, PGR, AKT1, MUC16, MUC1, CEACAM3
13duodenitis29.9GAST
14ovarian cyst29.9CEACAM3, MUC16, ESR2
15colon adenocarcinoma29.9MUC2, ESR2, CEACAM7
16squamous cell carcinoma29.9MUC16, CEACAM3, CEACAM7, VIM, AKT1, MUC1
17cholangiocarcinoma29.7MUC2, CEACAM3, MUC1
18endometriosis29.7FSHR, MUC16, PGR, ESR2
19leiomyosarcoma29.7VIM, MUC16, MUC1, PGR
20rhabdomyosarcoma29.7VIM, AKT1
21pancreas disease29.7GAST
22adenosquamous carcinoma29.7MUC2, MUC1, CEACAM7, PGR
23leiomyoma29.7VIM, ESR2, PGR
24osteosarcoma29.7BIRC5, ESR2
25hepatocellular carcinoma29.7CEACAM3, CEACAM7, BIRC5, AKT1, MUC2
26endometrial carcinoma29.7ESR2, PGR, MUC16, AKT1
27pancreatic cancer29.7CEACAM3, MUC2, GAST, AKT1, BIRC5, MUC1
28adenoma29.7CEACAM3, GAST, MUC2, ESR2, MUC1, BIRC5
29colon cancer29.7CEACAM3, CEACAM7, GAST, AKT1, MUC2, ESR2
30renal clear cell carcinoma29.7BIRC5, VIM, MUC1
31papillary cystadenocarcinoma10.9
32serous cystadenocarcinoma10.8
33ovarian cystadenocarcinoma10.8
34pancreatic cystadenocarcinoma10.7
35pancreatitis10.6
36appendix mucinous cystadenocarcinoma10.5
37hepatitis10.4
38breast mucinous cystadenocarcinoma10.4
39bile duct cystadenocarcinoma10.3
40pancreatic serous cystadenocarcinoma10.3
41acinar cell cystadenocarcinoma10.3
42zollinger-ellison syndrome10.2
43cystic teratoma10.2
44mature teratoma10.2
45prostatitis10.2
46pancreatic cystadenoma10.2
47mucinous adenocarcinoma10.1
48hepatitis a10.1
49appendix adenocarcinoma10.1
50breast mucinous carcinoma10.1

Graphical network of the top 20 diseases related to Cystadenocarcinoma:



Diseases related to cystadenocarcinoma

Clinical Features for Cystadenocarcinoma

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Drugs & Therapeutics for Cystadenocarcinoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Cystadenocarcinoma

Drug clinical trials:

Search ClinicalTrials for Cystadenocarcinoma

Search NIH Clinical Center for Cystadenocarcinoma

Search CenterWatch for Cystadenocarcinoma

Genetic Tests for Cystadenocarcinoma

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Anatomical Context for Cystadenocarcinoma

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32MalaCards
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MalaCards organs/tissues related to Cystadenocarcinoma:

32
Ovary, Pancreas, Appendix, Liver, Salivary gland, Colon, Breast, Lymph node, Prostate, Testis, Lung, Spleen, Kidney, Tongue, Skin, Bone, Testes, Eye, Endothelial, Cervix, Thyroid

Animal Models for Cystadenocarcinoma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Cystadenocarcinoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537610.1FSHR, PGR, MUC2, AKT1, USP14, GAST
2MP:000200610.0ESR2, GAST, AKT1, MUC2, MUC1, PGR
3MP:00053899.9USP14, USP2, AKT1, FSHR
4MP:00053799.8GAST, USP2, AKT1, MUC2, MUC1, PGR

Publications for Cystadenocarcinoma

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50PubMed
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Articles related to Cystadenocarcinoma:

(show top 50)    (show all 594)
idTitleAuthorsYear
1
Papillary cystadenocarcinoma of the mammary gland with metastases to the gastrointestinal tract in a Himalayan brown bear (Ursus arctos). (23805565)
2013
2
Central cystadenocarcinoma of the mandible. (22571862)
2012
3
Pancreatic Mucinous Cystadenocarcinoma Presenting with Splenic Infarction in a Young Female. (22222557)
2012
4
Successful surgical management of an extrahepatic biliary cystadenocarcinoma. (22355491)
2011
5
Intraductal carcinoma of salivary gland (so-called low-grade cribriform cystadenocarcinoma) arising in an intraparotid lymph node. (21442195)
2011
6
Primary intrahepatic biliary cystadenocarcinoma. (21679623)
2011
7
A case of intratesticular endometrioid papillary cystadenocarcinoma. (21474549)
2011
8
Serous papillary cystadenocarcinoma arising from autografted ovary of the abdominal wall. (19147508)
2010
9
Papillary serous cystadenocarcinoma of the stomach, peritoneum and ovary. (20163045)
2009
10
Collision tumor: serous cystadenocarcinoma and dermoid cyst in the same ovary. (18818939)
2009
11
Laparoscopic treatment of cystadenocarcinoma of the appendix penetrating in the sigmoid colon. (19793493)
2009
12
Serous cystadenocarcinoma of the ovary in an 11-year-old girl with extensive dissemination and chylothorax: a case report and a brief review of literature. (19564753)
2009
13
An extremely rare cause of acute abdomen in pregnancy: ruptured pancreatic mucinous cystadenocarcinoma. (17446849)
2007
14
Improved early diagnosis of cystadenocarcinoma of the pancreas. (17287173)
2007
15
Immunohistochemical identification of primary peritoneal serous cystadenocarcinoma mimicking advanced colorectal carcinoma: a case report. (18036260)
2007
16
Acinar cell cystadenocarcinoma of the pancreas in a 4-year-old child. (17003655)
2006
17
Hepatobiliary cystadenocarcinoma without mesenchymal stroma showing a good prognosis. (16872329)
2006
18
Multifocal biliary cystadenocarcinoma of the liver: CT and pathologic findings. (17036531)
2006
19
Papillary cystadenocarcinoma arising in the floor of the mouth: report of a case. (16631500)
2006
20
Is there a role for chemoradiation in the management of cystadenocarcinoma of the pancreas? (15968257)
2005
21
Mucinous cystadenocarcinoma of the pancreas in an adolescent with cystic fibrosis. (16010483)
2005
22
Cystadenoma and cystadenocarcinoma of the liver: a single center experience. (15848365)
2005
23
Cystadenocarcinoma in the ovary of a Thoroughbred mare. (15957389)
2005
24
Biliary cystadenocarcinoma associated with atrophy of the left hepatic lobe and hepatolithiasis mimicking intrahepatic cholangiocarcinoma: a case report. (15191223)
2004
25
Mucinous cystadenocarcinoma of the breast coexisting with infiltrating ductal carcinoma. (15482568)
2004
26
Pulmonary mucinous cystadenocarcinoma: report of a case and review of the literature. (14602331)
2003
27
Calcified "Sister Mary Joseph" umbilical metastasis from ovarian cystadenocarcinoma seen on an MDP bone scintigram. (11786748)
2002
28
Thyroid cystadenocarcinoma in a saker falcon (Falco cherrug). (11558665)
2001
29
Virilization during pregnancy caused by ovarian mucinous cystadenocarcinoma. (11328230)
2001
30
Ovarian mucinous cystadenocarcinoma with yolk sac tumor in a 71-year-old woman. (12090598)
1999
31
Mucinous cystadenocarcinoma of the spleen presenting a point mutation of the Kirsten-ras oncogene at codon 12. (10219836)
1999
32
Mucinous cystic neoplasm (mucinous cystadenocarcinoma of low-grade malignant potential) of the pancreas: a clinicopathologic study of 130 cases. (9888699)
1999
33
Ovarian mucinous cystadenocarcinoma with malignant mural nodules. (9736414)
1998
34
Mucinous cystadenocarcinoma of the lung. (9803072)
1998
35
Mucinous biliary cystadenocarcinoma containing gas bubbles secondary to duodenal invasion. (9849396)
1998
36
High-grade papillary cystadenocarcinoma of the tongue. (9279572)
1997
37
Peritoneal fluid cytology in advanced mucinous cystadenocarcinoma of the pancreas. (8629396)
1996
38
Asymptomatic primary mucinous cystadenocarcinoma of the appendix with a large abdominal mass: report of a case. (7894191)
1994
39
Establishment and characterization of a human ovarian serous cystadenocarcinoma cell line that produces the tumor markers CA-125 and tissue polypeptide antigen. (2314830)
1990
40
Osseous metaplasia in ovarian papillary serous cystadenocarcinoma. (2121630)
1990
41
Cystadenocarcinoma versus pseudocyst of the pancreas: a difficult differential diagnosis. (2666031)
1989
42
Gastrin-producing ovarian cystadenocarcinoma: sensitivity to secretin and SMS 201-995. (2473000)
1989
43
Parovarian cystadenocarcinoma of low-malignant potential. (3371747)
1988
44
Ovarian mucinous cystadenocarcinoma producing alpha-fetoprotein. (2456275)
1988
45
Primary retroperitoneal mucinous cystadenocarcinoma. (3282642)
1988
46
Papillary cystadenocarcinoma of the prostate. (6708240)
1984
47
Characterization of a cell line derived from the ascites of a patient with papillary serous cystadenocarcinoma of the ovary. (6583437)
1984
48
A clinicopathologic study of 21 cases of pancreatic cystadenocarcinoma. (718294)
1978
49
Mucosal hyperplasia, mucinous cystadenoma, and mucinous cystadenocarcinoma of the appendix. A re-evaluation of appendiceal "mucocele". (4757938)
1973
50
Papillary cystadenocarcinoma of the pancreas; case report. (12986668)
1952

Genetic Variations for Cystadenocarcinoma

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Expression for genes affiliated with Cystadenocarcinoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cystadenocarcinoma

Search GEO for disease gene expression data for Cystadenocarcinoma.

Pathways for genes affiliated with Cystadenocarcinoma

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37NCBI BioSystems Database, 53Reactome, 29KEGG
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Pathways related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.3FSHR, PGR, ESR2
2
Hide members
10.3MUC1, MUC16, MUC2
310.2AKT1, AMY1C, AMY1B, AMY1A
4
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10.1GAST, AMY1C, AMY1B, AMY1A

Compounds for genes affiliated with Cystadenocarcinoma

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44Novoseek, 49PharmGKB, 28IUPHAR, 11DrugBank, 59Tocris Bioscience, 24HMDB, 2BitterDB
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Compounds related to Cystadenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 69)
idCompoundScoreTop Affiliating Genes
1estrogen4410.9CEACAM7
2butyrate4410.8CEACAM7
3sialic acid4410.7CEACAM3, FSHR
4cycloheximide4410.7CEACAM7
5dexamethasone44 49 28 1113.7AKT1, MUC2, MUC16, BIRC5
6mucicarmine4410.6CEACAM3, CEACAM7, MUC1, VIM
7metronidazole44 1111.6GAST, MUC1, CEACAM3
84-hydroxytamoxifen4410.6VIM, AKT1, ESR2, PGR
9progestin4410.6ESR2, PGR, MUC1, VIM
10dtpa4410.6GAST, MUC1, CEACAM3
11hematoxylin4410.6VIM, MUC2, MUC16, MUC1, CEACAM3
12b 7234410.6MUC1, CEACAM3, CEACAM7, MUC16, VIM
13creatinine4410.6GAST, MUC16, CEACAM3
14resveratrol44 59 11 2413.6GAST, PGR
15mifepristone44 59 28 1113.6ESR2, BIRC5, MUC1, PGR
16gefitinib44 49 1112.6ESR2, CEACAM7, AKT1, VIM, BIRC5
17crcs4410.6MUC1, BIRC5, MUC2
18agar4410.5BIRC5, PGR, AKT1, VIM, MUC1
19adriamycin4410.5PGR, MUC1, CEACAM3, BIRC5, VIM, AKT1
20dmso4410.5MUC2, ESR2, BIRC5, VIM, MUC1, PGR
21thymidylate4410.5CEACAM3, ESR2, BIRC5, VIM
22methotrexate44 49 1112.5PGR, MUC1, BIRC5, CEACAM3, MUC2, VIM
23paclitaxel44 49 1112.5PGR, BIRC5, MUC16, AKT1
245fluorouracil4410.5PGR, MUC2, MUC1, CEACAM3, CEACAM7, BIRC5
25gnrh4410.5ESR2, PGR, FSHR, GAST, VIM, AKT1
26tamoxifen44 49 28 1113.5BIRC5, CEACAM3, ESR2, VIM, AKT1, MUC1
27estradiol44 11 2412.5PGR, VIM, MUC16, MUC1, BIRC5, FSHR
28actinomycin d4410.5MUC2, BIRC5, ESR2, CEACAM7, MUC1, AKT1
29dihydrotestosterone44 28 11 2413.5ESR2, VIM, MUC1, PGR
30sb 20358044 5911.5BIRC5, MUC2, GAST, VIM, AKT1
31doxorubicin44 49 1112.4MUC16, PGR, BIRC5, CEACAM3, ESR2, AKT1
32thymidine44 2411.4CEACAM3, FSHR, MUC1, GAST, CEACAM7, BIRC5
33adenylate4410.4VIM, PGR, AKT1, GAST, FSHR, ESR2
34steroid4410.4CEACAM3, FSHR, BIRC5, MUC16
35retinoic acid44 2411.4BIRC5, VIM, AKT1, MUC2, MUC1, PGR
36paraffin4410.4MUC2, MUC1, BIRC5, ESR2, AKT1, VIM
37thyroxine44 2411.3PGR, CEACAM7, CEACAM3, GAST
38testosterone44 59 11 2413.3ESR2, MUC16, MUC1, BIRC5, PGR, FSHR
39alanine4410.3FSHR, BIRC5, PGR, GAST, VIM, AKT1
40vegf4410.3MUC1, PGR, BIRC5, ESR2, CEACAM3, MUC16
415-aza-2deoxycytidine4410.3VIM, MUC2, PGR, ESR2
42cysteine4410.3FSHR, PGR, VIM, AKT1, MUC1, MUC2
43progesterone44 59 28 11 2414.3CEACAM3, VIM, MUC2, MUC16, MUC1, PGR
44genistein44 28 59 2 11 2415.3VIM, AKT1, PGR, BIRC5, ESR2
45serine4410.3BIRC5, MUC1, MUC16, MUC2, AKT1, GAST
46indium4410.2CEACAM3, MUC1
47folate4410.2PGR, MUC1, GAST, VIM
48glucose4410.2AKT1, MUC2, CEACAM3, BIRC5, MUC16, MUC1
49threonine4410.1AKT1, FSHR, MUC1, MUC16, MUC2, BIRC5
50fundal4410.0GAST, PGR

GO Terms for genes affiliated with Cystadenocarcinoma

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16Gene Ontology
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Cellular components related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:00579610.3MUC1, MUC16, MUC2

Biological processes related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1O-glycan processingGO:01626610.3MUC1, MUC16, MUC2

Molecular functions related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1enzyme bindingGO:01989910.2ESR2, BIRC5, PGR, AKT1
2protein bindingGO:0055159.1ESR2, VIM, AMY1C, UBE4A, GAST, USP14

Products for genes affiliated with Cystadenocarcinoma

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Sources for Cystadenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet