MCID: CYS014
MIFTS: 55

Cystadenocarcinoma malady

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Summaries for Cystadenocarcinoma

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Disease Ontology:8 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, in which cystic accumulations of retained secretions are formed.

MalaCards based summary: Cystadenocarcinoma, also known as cystadenocarcinoma nos, is related to ovarian mucinous cystadenocarcinoma and cystadenoma. An important gene associated with Cystadenocarcinoma is MUC1 (mucin 1, cell surface associated), and among its related pathways are O-linked glycosylation of mucins and EGFR Signaling Pathway. The compounds eosin and s 100 have been mentioned in the context of this disorder. Affiliated tissues include ovary, pancreas and liver, and related mouse phenotypes are muscle and integument.

Wikipedia:65 Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from... more...

Aliases & Classifications for Cystadenocarcinoma

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Sources:
8Disease Ontology, 44Novoseek, 62UMLS, 57SNOMED-CT, 34MeSH, 39NCIt
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Cystadenocarcinoma, Aliases & Descriptions:

Name: Cystadenocarcinoma 8 44 62
 
Cystadenocarcinoma Nos 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:3111
MeSH34 D003536
SNOMED-CT57 21008007, 189681005
NCIt39 C2971

Related Diseases for Cystadenocarcinoma

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Diseases related to Cystadenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 161)
idRelated DiseaseScoreTop Affiliating Genes
1ovarian mucinous cystadenocarcinoma31.8FSHR
2cystadenoma31.8FSHR
3pseudomyxoma peritonei31.3MUC2
4giant cell tumor30.8MUC1, VIM
5papillary adenocarcinoma30.5MUC2, MUC1
6angiosarcoma30.2VIM, MUC1
7adenosquamous carcinoma30.1MUC2, PGR, MUC1
8leiomyosarcoma30.0PGR, VIM, MUC1
9cholangiocarcinoma29.8MUC1, MUC2
10endometriosis29.8ESR2, PGR, FSHR
11pancreatic cancer29.8BIRC5, AKT1, MUC2
12leiomyoma29.7VIM, PGR, ESR2
13endometrial carcinoma29.7AKT1, ESR2, PGR
14ovarian cancer29.4ESR2, MUC2, BIRC5, PGR, MUC1
15adenoma29.2MUC2, MUC1, FSHR, BIRC5, ESR2
16adenocarcinoma29.0ESR2, VIM, MUC2, MUC1, FSHR, AKT1
17mucinous cystadenocarcinoma11.1
18serous cystadenocarcinoma10.9
19papillary cystadenocarcinoma10.9
20pancreatitis10.7
21ovarian cystadenocarcinoma10.7
22pancreatic cystadenocarcinoma10.6
23ovarian serous cystadenocarcinoma10.5
24hidradenoma10.5MUC1
25syringoma10.5MUC1
26peritonitis10.5
27progesterone resistance10.5PGR
28hepatitis10.5
29biliary papillomatosis10.5MUC2
30adenomatoid tumor10.4VIM
31paraganglioma10.4VIM
32acinar cell cystadenocarcinoma10.4
33pancreatic serous cystadenocarcinoma10.3
34teratoma10.3
35mammary paget's disease10.3MUC1, PGR
36sertoli-leydig cell tumor10.3MUC1, PGR
37secretory meningioma10.3MUC1, VIM
38clear cell ependymoma10.3VIM, MUC1
39mesenchymal chondrosarcoma10.3MUC1, VIM
40spindle cell sarcoma10.3MUC1, VIM
41zollinger-ellison syndrome10.3
42bile duct cystadenocarcinoma10.3
43cystic teratoma10.3
44prostatitis10.3
45epithelioid sarcoma10.3MUC1, VIM
46dermatofibrosarcoma protuberans10.3VIM, MUC1
47rhabdoid tumor10.3MUC1, VIM
48perineurioma10.3VIM, MUC1
49hemangiopericytoma10.3VIM, MUC1
50malignant mixed mullerian tumor10.3VIM, PGR

Graphical network of the top 20 diseases related to Cystadenocarcinoma:



Diseases related to cystadenocarcinoma

Symptoms for Cystadenocarcinoma

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Drugs & Therapeutics for Cystadenocarcinoma

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Drug clinical trials:

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Genetic Tests for Cystadenocarcinoma

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Anatomical Context for Cystadenocarcinoma

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MalaCards organs/tissues related to Cystadenocarcinoma:

32
Ovary, Pancreas, Liver, Appendix, Salivary gland, Breast, Colon, Lymph node, Prostate, Testis, Lung, Spleen, Kidney, Skin, Tongue, Eye, Bone, Testes, Small intestine, Thyroid, Cervix, Endothelial

Animal Models for Cystadenocarcinoma or affiliated genes

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MGI Mouse Phenotypes related to Cystadenocarcinoma:

36 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.2AKT1, VIM, ESR2, PGR
2MP:00107718.1PGR, ESR2, MUC1, FSHR, AKT1
3MP:00020067.8AKT1, PGR, ESR2, MUC2, MUC1, FSHR
4MP:00028737.8BIRC5, AKT1, MUC1, ESR2, PGR
5MP:00053897.7PGR, ESR2, VIM, FSHR, AKT1
6MP:00053797.7PGR, ESR2, MUC2, MUC1, FSHR, AKT1
7MP:00053867.5PGR, ESR2, VIM, FSHR, AKT1
8MP:00053857.5PGR, ESR2, VIM, MUC2, FSHR, AKT1
9MP:00053977.0PGR, ESR2, VIM, MUC2, FSHR, AKT1
10MP:00053877.0PGR, ESR2, VIM, MUC2, FSHR, AKT1
11MP:00053846.9PGR, ESR2, VIM, MUC2, FSHR, AKT1
12MP:00107686.9PGR, ESR2, VIM, MUC2, FSHR, AKT1
13MP:00053766.7PGR, ESR2, VIM, MUC2, MUC1, FSHR

Publications for Cystadenocarcinoma

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Articles related to Cystadenocarcinoma:

(show top 50)    (show all 615)
idTitleAuthorsYear
1
Paratesticular papillary serous cystadenocarcinoma: A rare entity in Indian population. (25308020)
2014
2
Primary mucinous cystadenocarcinoma of the breast with amplification of the HER2 gene confirmed by FISH - case report and review of the literature. (25119013)
2014
3
Papillary cystadenocarcinoma of the mammary gland with metastases to the gastrointestinal tract in a Himalayan brown bear (Ursus arctos). (23805565)
2013
4
Serous papillary cystadenocarcinoma in supernumerary ovary. (23550880)
2013
5
Peritoneal papillary serous cystadenocarcinoma at a previous laparoscopic trocar site. (23040941)
2012
6
Successful surgical management of an extrahepatic biliary cystadenocarcinoma. (22355491)
2011
7
Primary retroperitoneal mucinous cystadenocarcinoma: a case report and review of the literature. (20558993)
2010
8
Successful left hemihepatectomy and perioperative management of a patient with biliary cystadenocarcinoma, complicated with MELAS syndrome: report of a case. (20740354)
2010
9
Cytological features of cystadenocarcinoma in cyst fluid of the parotid gland: Diagnostic pitfalls and literature review. (19927358)
2010
10
Biliary cystadenocarcinoma of the gall bladder: a case report. (19946551)
2009
11
Huge liver abscess radiologically mimicking cystadenocarcinoma. (19725434)
2009
12
Gingival metastasis from ovarian mucinous cystadenocarcinoma as an initial manifestation (a rare case report). (19246966)
2008
13
Papillary cystadenocarcinoma of the prostate: a case report. (17310773)
2007
14
Mucinous cystadenocarcinoma of the pancreas developing during hormone replacement therapy. (17372823)
2007
15
Cystadenocarcinoma of salivary gland presenting as a cystic lesion in the mandible. (16448922)
2006
16
Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma. (17007033)
2006
17
Mucinous cystadenocarcinoma--an extremely rare tumor in a young patient. (16639689)
2006
18
Peritoneal mucinous cystadenocarcinoma of probable urachal origin: a challenging diagnosis. (17021133)
2006
19
Mammary mucinous cystadenocarcinoma. (17163855)
2006
20
Acinar cell cystadenocarcinoma of the pancreas: report of rare case and review of the literature. (15619219)
2004
21
Biliary cystadenocarcinoma associated with atrophy of the left hepatic lobe and hepatolithiasis mimicking intrahepatic cholangiocarcinoma: a case report. (15191223)
2004
22
Plasma cell leukaemia with papillary serous cystadenocarcinoma of ovary--a case report. (15025299)
2003
23
Giant mucinous cystadenocarcinoma: a case report. (12552327)
2003
24
Co-existent ovarian mucinous cystadenocarcinoma and ovarian choriocarcinoma. (12192487)
2002
25
Treatment of a case of primary retroperitoneal mucinous cystadenocarcinoma: is adjuvant hysterectomy and bilateral salpingo-oophorectomy justified? (12114915)
2002
26
DIC-CT findings of biliary cystadenocarcinoma communicating with the bile duct: a case report. (11490785)
2001
27
Renal microcystic tubular lesions in two 1Year-old dogs - an early sign of hereditary renal cystadenocarcinoma? (11032680)
2000
28
Estrogen receptor alpha (ER-alpha) and beta (ER-beta) mRNAs in normal ovary, ovarian serous cystadenocarcinoma and ovarian cancer cell lines: down-regulation of ER-beta in neoplastic tissues. (9506768)
1998
29
Serous cystadenocarcinoma and ovarian teratoma during pregnancy. (8737305)
1996
30
Primary retroperitoneal mucinous cystadenocarcinoma of low malignant potential: a case report and literature review. (8626105)
1996
31
Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. (7644647)
1995
32
Liver metastases from ovarian cystadenocarcinoma masquerading on CT as lobar fatty infiltration. (8370842)
1993
33
Mucinous cystadenocarcinoma of the pancreas with liver metastases. An unusual presentation of a rare tumor. (8239476)
1993
34
Immuno-histological characterization of OVS1 and OVS2 monoclonal antibodies recognizing human ovarian mucinous cystadenocarcinoma. (1284830)
1992
35
Cystadenocarcinoma of the pancreas: neo-adjuvant therapy and CEA monitoring. (2296199)
1990
36
Primary retroperitoneal mucinous cystadenocarcinoma: report of a case. (2075232)
1990
37
Mucinous cystadenocarcinoma of the appendix. A rare tumor of the right iliac fossa]. (2262520)
1990
38
Hyperamylasemia with papillary serous cystadenocarcinoma of the ovary. (2482644)
1989
39
Unique appearance of the duodenal papilla in pancreatic cystadenocarcinoma. (2539985)
1989
40
Cystadenocarcinoma versus pseudocyst of the pancreas: a difficult differential diagnosis. (2666031)
1989
41
Simultaneous occurrence of a granulosa cell tumour and a serous papillary cystadenocarcinoma in the same ovary. A case report. (4036607)
1985
42
Papillary cystadenocarcinoma of the prostate. (6708240)
1984
43
Spontaneous papillary cystadenocarcinoma of the ovary in Dunkin-Hartley guineapigs. (7359885)
1980
44
Metastatic, papillary cystadenocarcinoma of the mammary gland in a black-footed ferret. (7463613)
1980
45
Intratesticular papillary mucinous cystadenocarcinoma. (483506)
1979
46
Classification and survival rate of patients with serous cystadenocarcinoma of the ovaries. (1004656)
1976
47
An autopsy case of mucinous cystadenocarcinoma of the liver. (1025932)
1976
48
An immunologic comparison between serous cystadenocarcinoma of the ovary and other human gynecologic tumors. (4126800)
1973
49
Papillary cystadenocarcinoma of the pancreas; case report. (12986668)
1952
50
Calcified metastatic deposits in the peritoneal cavity, liver and right lung field from papillary cystadenocarcinoma of the ovary. (14771326)
1950

Variations for Cystadenocarcinoma

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Expression for genes affiliated with Cystadenocarcinoma

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Expression patterns in normal tissues for genes affiliated with Cystadenocarcinoma

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Pathways for genes affiliated with Cystadenocarcinoma

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Pathways related to Cystadenocarcinoma according to GeneCards/GeneDecks:

(show all 14)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7MUC1, MUC2
29.6MUC1, AKT1
39.6FSHR, AKT1
4
Show member pathways
Cell cycle ESR1 regulation of G1 S transition60
Immune response MIF JAB1 signaling60
Cell cycle Cell cycle generic schema 60
9.5AKT1, PGR
5
Show member pathways
9.4AKT1, VIM
6
Show member pathways
Signaling by Aurora kinases37
Aurora C signaling37
9.3BIRC5, VIM
79.3BIRC5, AKT1
89.3BIRC5, AKT1
9
Show member pathways
Nuclear Receptors37
9.2ESR2, PGR
109.1AKT1, ESR2
11
Show member pathways
IL-9 Signaling Pathway37
Development Thrombopoietin regulated cell processes60
IL-7 Signaling Pathway37
Immune response IL 9 signaling pathway60
9.0BIRC5, AKT1, MUC1
128.9FSHR, ESR2, PGR
13
Show member pathways
8.6AKT1, VIM, ESR2
14
Show member pathways
8.3ESR2, VIM, MUC1, AKT1

Compounds for genes affiliated with Cystadenocarcinoma

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Compounds related to Cystadenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 113)
idCompoundScoreTop Affiliating Genes
1eosin449.8MUC1, VIM
2s 100449.6MUC1, VIM
3hematoxylin449.4MUC2, VIM, MUC1
4crcs449.4MUC2, MUC1, BIRC5
5trastuzumab44 50 1111.4PGR, MUC1, BIRC5
6nandrolone44 2410.2PGR, ESR2
7gemcitabine44 50 1111.2BIRC5, AKT1, MUC1
8trilostane44 1110.1PGR, ESR2
9nocodazole44 1110.0VIM, BIRC5, AKT1
10sialic acid449.0FSHR, MUC2, MUC1
115fluorouracil449.0PGR, MUC1, BIRC5, MUC2
12vincristine44 50 1111.0BIRC5, AKT1, VIM
13ribonucleic acid448.9ESR2, FSHR, MUC1, PGR
14progestin448.8PGR, ESR2, VIM, MUC1
15dihydrotestosterone44 28 24 1111.8PGR, MUC1, VIM, ESR2
16paclitaxel44 50 1110.7BIRC5, AKT1, VIM, PGR
17resveratrol44 61 24 1111.7PGR, BIRC5, ESR2
18thymidylate448.7ESR2, VIM, BIRC5
19sb 20358044 619.7BIRC5, MUC2, VIM, AKT1
20mifepristone44 28 61 1111.7MUC1, BIRC5, PGR, ESR2
215-aza-2deoxycytidine448.6VIM, ESR2, PGR, MUC2
224-hydroxytamoxifen448.6VIM, AKT1, ESR2, PGR
23methotrexate50 44 1110.5BIRC5, MUC2, VIM, PGR, MUC1
24adriamycin448.5VIM, PGR, AKT1, BIRC5, MUC1
25agar448.5BIRC5, AKT1, PGR, VIM, MUC1
26threonine448.5FSHR, MUC2, AKT1, MUC1, BIRC5
27butyrate448.4BIRC5, AKT1, MUC1, MUC2, VIM
28gefitinib44 50 1110.4AKT1, VIM, ESR2, BIRC5
29alanine448.3BIRC5, PGR, AKT1, VIM, FSHR
30etoposide44 50 61 1111.3BIRC5, AKT1, VIM, ESR2
31rapamycin448.3BIRC5, ESR2, VIM, AKT1
32gnrh448.2FSHR, PGR, ESR2, VIM, AKT1
33lipid448.2VIM, FSHR, MUC1, BIRC5, AKT1
34adenylate448.2AKT1, PGR, ESR2, VIM, FSHR
35doxorubicin44 50 1110.0BIRC5, PGR, AKT1, VIM, ESR2
36genistein44 28 61 2 24 1113.0VIM, ESR2, PGR, AKT1, BIRC5
37cycloheximide447.9ESR2, PGR, AKT1, VIM, BIRC5
38estradiol44 24 119.8VIM, MUC1, FSHR, BIRC5, ESR2, PGR
39dmso447.7BIRC5, MUC1, MUC2, VIM, ESR2, PGR
40tamoxifen44 50 28 1110.7AKT1, ESR2, VIM, PGR, MUC1, BIRC5
41vegf447.6PGR, ESR2, BIRC5, AKT1, MUC1, VIM
42actinomycin d447.6AKT1, ESR2, VIM, MUC2, MUC1, BIRC5
43cysteine447.4AKT1, VIM, ESR2, PGR, FSHR, MUC1
44progesterone44 28 61 24 1111.4MUC1, ESR2, VIM, MUC2, FSHR, BIRC5
45testosterone44 61 24 1110.3FSHR, PGR, ESR2, VIM, MUC1, AKT1
46paraffin447.2PGR, MUC1, MUC2, VIM, ESR2, BIRC5
47dexamethasone44 50 28 1110.2BIRC5, AKT1, MUC1, VIM, ESR2, PGR
48serine447.2FSHR, VIM, AKT1, MUC1, MUC2, BIRC5
49retinoic acid44 248.2ESR2, VIM, MUC2, PGR, MUC1, AKT1
50estrogen446.9AKT1, PGR, ESR2, VIM, BIRC5, MUC1

GO Terms for genes affiliated with Cystadenocarcinoma

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Biological processes related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1O-glycan processingGO:0162669.4MUC1, MUC2
2negative regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:0431549.3BIRC5, AKT1
3uterus developmentGO:0600659.2FSHR, ESR2

Molecular functions related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1steroid bindingGO:0054969.2ESR2, PGR
2ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activityGO:0048799.1PGR, ESR2
3steroid hormone receptor activityGO:0037078.9ESR2, PGR
4identical protein bindingGO:0428028.8BIRC5, AKT1, VIM
5enzyme bindingGO:0198998.2BIRC5, AKT1, ESR2, PGR
6protein bindingGO:0055156.5PGR, ESR2, VIM, MUC2, MUC1, FSHR

Products for genes affiliated with Cystadenocarcinoma

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Sources for Cystadenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet