MCID: CYS014
MIFTS: 52

Cystadenocarcinoma malady

Summaries for Cystadenocarcinoma

About this section
Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Disease Ontology:8 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, in which cystic accumulations of retained secretions are formed.

MalaCards: Cystadenocarcinoma, also known as cystadenocarcinoma nos, is related to mucinous cystadenocarcinoma and ovarian mucinous cystadenocarcinoma. An important gene associated with Cystadenocarcinoma is FSHR (follicle stimulating hormone receptor), and among its related pathways are Ovarian Infertility Genes and O-linked glycosylation of mucins. The compounds estrogen and butyrate have been mentioned in the context of this disorder. Affiliated tissues include ovary, pancreas and appendix, and related mouse phenotypes are homeostasis/metabolism and tumorigenesis.

Wikipedia:63 Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from... more...

Aliases & Classifications for Cystadenocarcinoma

About this section
Sources:
8Disease Ontology, 44Novoseek, 60UMLS, 39NCIt, 34MeSH, 56SNOMED-CT
See all sources

Aliases & Descriptions:

cystadenocarcinoma 8 44 60
cystadenocarcinoma nos 8


External Ids:

Disease Ontology8 DOID:3111
NCIt39 C2971
SNOMED-CT56 21008007, 189681005
MeSH34 D003536

Related Diseases for Cystadenocarcinoma

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Cystadenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 201)
idRelated DiseaseScoreTop Affiliating Genes
1mucinous cystadenocarcinoma31.5CEACAM7, MUC1, MUC16, CEACAM3
2ovarian mucinous cystadenocarcinoma31.0LMX1A, FSHR
3cystadenoma30.9FSHR, CEACAM3
4ovarian serous cystadenocarcinoma30.9ZNF217, USP2, USP14, UBE4A, MUC16
5peritonitis30.6MUC16
6pseudomyxoma peritonei30.5MUC2
7adenocarcinoma30.4CEACAM3, GAST, AKT1, MUC2, MUC16, MUC1
8sarcoma30.3MUC1, VIM
9giant cell tumor30.3CEACAM3, VIM, MUC1
10papillary carcinoma30.2MUC1, MUC16, CEACAM3, PGR, MUC2
11papillary adenocarcinoma30.1MUC2, MUC16, MUC1
12ovarian cancer30.1ESR2, PGR, AKT1, MUC16, MUC1, CEACAM3
13duodenitis29.9GAST
14ovarian cyst29.9CEACAM3, MUC16, ESR2
15colon adenocarcinoma29.9MUC2, ESR2, CEACAM7
16squamous cell carcinoma29.9MUC16, CEACAM3, CEACAM7, VIM, AKT1, MUC1
17cholangiocarcinoma29.7MUC2, CEACAM3, MUC1
18endometriosis29.7FSHR, MUC16, PGR, ESR2
19leiomyosarcoma29.7VIM, MUC16, MUC1, PGR
20rhabdomyosarcoma29.7VIM, AKT1
21pancreas disease29.7GAST
22adenosquamous carcinoma29.7MUC2, MUC1, CEACAM7, PGR
23leiomyoma29.7VIM, ESR2, PGR
24osteosarcoma29.7BIRC5, ESR2
25hepatocellular carcinoma29.7CEACAM3, CEACAM7, BIRC5, AKT1, MUC2
26endometrial carcinoma29.7ESR2, PGR, MUC16, AKT1
27pancreatic cancer29.7CEACAM3, MUC2, GAST, AKT1, BIRC5, MUC1
28adenoma29.7CEACAM3, GAST, MUC2, ESR2, MUC1, BIRC5
29colon cancer29.7CEACAM3, CEACAM7, GAST, AKT1, MUC2, ESR2
30renal clear cell carcinoma29.7BIRC5, VIM, MUC1
31papillary cystadenocarcinoma10.9
32serous cystadenocarcinoma10.8
33ovarian cystadenocarcinoma10.8
34pancreatic cystadenocarcinoma10.7
35pancreatitis10.6
36appendix mucinous cystadenocarcinoma10.5
37hepatitis10.4
38breast mucinous cystadenocarcinoma10.4
39bile duct cystadenocarcinoma10.3
40pancreatic serous cystadenocarcinoma10.3
41acinar cell cystadenocarcinoma10.3
42zollinger-ellison syndrome10.2
43cystic teratoma10.2
44mature teratoma10.2
45prostatitis10.2
46pancreatic cystadenoma10.2
47mucinous adenocarcinoma10.1
48hepatitis a10.1
49appendix adenocarcinoma10.1
50breast mucinous carcinoma10.1

Graphical network of the top 20 diseases related to Cystadenocarcinoma:



Diseases related to cystadenocarcinoma

Clinical Features for Cystadenocarcinoma

About this section

Drugs & Therapeutics for Cystadenocarcinoma

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Cystadenocarcinoma

Drug clinical trials:

Search ClinicalTrials for Cystadenocarcinoma

Search NIH Clinical Center for Cystadenocarcinoma

Search CenterWatch for Cystadenocarcinoma

Genetic Tests for Cystadenocarcinoma

About this section

Anatomical Context for Cystadenocarcinoma

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Cystadenocarcinoma:

32
Ovary, Pancreas, Appendix, Liver, Salivary gland, Colon, Breast, Lymph node, Prostate, Testis, Lung, Spleen, Kidney, Tongue, Skin, Testes, Bone, Eye, Cervix, Endothelial, Thyroid

Animal Models for Cystadenocarcinoma or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Cystadenocarcinoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537610.1FSHR, PGR, MUC2, AKT1, USP14, GAST
2MP:000200610.0ESR2, GAST, AKT1, MUC2, MUC1, PGR
3MP:00053899.9USP14, USP2, AKT1, FSHR
4MP:00053799.8GAST, USP2, AKT1, MUC2, MUC1, PGR

Publications for Cystadenocarcinoma

About this section
Sources:
50PubMed
See all sources

Articles related to Cystadenocarcinoma:

(show top 50)    (show all 594)
idTitleAuthorsYear
1
Cytomorphological findings and histological correlation of low-grade cribriform cystadenocarcinoma of salivary gland in fine-needle aspiration: a case study. (24421856)
2013
2
Peritoneal papillary serous cystadenocarcinoma at a previous laparoscopic trocar site. (23040941)
2012
3
Imaging features of intrahepatic biliary cystadenoma and cystadenocarcinoma on B-mode and contrast-enhanced ultrasound. (23154870)
2012
4
Appendiceal mucinous cystadenocarcinoma with implantation metastasis to the incision scar and cutaneous fistula. (20585997)
2012
5
Primary pulmonary mucinous cystadenocarcinoma: presentation of a case and a review of the literature. (21439701)
2011
6
Biliary cystadenocarcinoma diagnosed with real-time contrast-enhanced ultrasonography: report of a case with diagnostic features. (20039461)
2010
7
Recurrent pneumonia due to an appendiceal mucinous cystadenocarcinoma: a rare presentation of a rare malignancy. (20689604)
2009
8
Mucinous cystadenocarcinoma of the renal pelvis: a case report and clues to histogenesis. (21686862)
2009
9
Gingival metastasis from ovarian mucinous cystadenocarcinoma as an initial manifestation (a rare case report). (19246966)
2008
10
Cystadenocarcinoma and leiomyoma in a peregrine falcon (Falco peregrinus brookei). (18587064)
2008
11
Fine-needle aspiration cytology of pulmonary mucinous cystadenocarcinoma. (18618726)
2008
12
Primary retroperitoneal mucinous cystadenocarcinoma associated with pregnancy. (18028384)
2008
13
Primary retroperitoneal mucinous cystadenocarcinoma: report of two cases. (17224073)
2007
14
Retroperitoneal mucinous cystadenocarcinoma in a man: case report and review of the literature. (17208139)
2007
15
Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma. (17007033)
2006
16
Effects of antisense oligodeoxynucleotide to follicle-stimulating hormone receptor on the expression of proliferating cell nuclear antigen and vascular endothelial growth factor in primary culture cells derived from human ovarian mucinous cystadenocarcinoma. (16711022)
2006
17
Paratesticular papillary serous cystadenocarcinoma--a case report. (16625973)
2006
18
Primary retroperitoneal mucinous cystadenocarcinoma in a male patient. (16731606)
2006
19
Biliary cystadenocarcinoma presenting as recurrent cholangitis. (16546513)
2006
20
Osteoclast-like giant cell tumor in mucinous cystadenocarcinoma of the pancreas: an immunohistochemical and molecular analysis. (15734212)
2005
21
Successful complete resection of biliary cystadenocarcinoma after percutaneous transhepatic portal embolization. (15855934)
2005
22
Hilar biliary cystadenocarcinoma: an uncommon hepatic neoplasm. (15471326)
2004
23
Paratesticular mucinous cystadenocarcinoma: metastasis from pancreatic cancer. (15663694)
2004
24
Late complication of a large simple cyst of the liver mimicking cystadenocarcinoma after sclerotherapy. (12876027)
2003
25
Management of hepatobiliary cystadenocarcinoma. (12637809)
2003
26
Intrahepatic cystadenocarcinoma with pleural dissemination: a case report. (15179833)
2003
27
Hepatic resection of metastatic tumor from serous cystadenocarcinoma of the ovary. (12068151)
2002
28
Intraductal papillary mucinous cystadenocarcinoma of the pancreas with intrapancreatic perineural invasion. (11893941)
2002
29
Papillary cystadenocarcinoma arising from minor salivary glands in the anterior portion of the tongue: a case report. (11772498)
2002
30
Liver cystadenocarcinoma--case report. (12211739)
2001
31
Renal microcystic tubular lesions in two 1Year-old dogs - an early sign of hereditary renal cystadenocarcinoma? (11032680)
2000
32
A case of biliary cystadenocarcinoma. (9159050)
1997
33
Anaplastic carcinoma showing rhabdoid features combined with mucinous cystadenocarcinoma of the pancreas. (9341593)
1997
34
Primary retroperitoneal mucinous cystadenocarcinoma of low malignant potential: a case report and literature review. (8626105)
1996
35
Ovarian-type papillary serous cystadenocarcinoma of the testis. (8653294)
1996
36
Comparison between a newly established pancreatic cystadenocarcinoma cell-line, ocup-1 and cells derived from pancreatic ductal carcinoma. (21567058)
1994
37
Papillary cystadenocarcinoma of the sublingual gland presenting as a ranula. (1510905)
1992
38
A case of primary retroperitoneal mucinous cystadenocarcinoma. (1561906)
1992
39
Cytoreductive surgery and intraperitoneal chemotherapy with peritoneal spread of cystadenocarcinoma. (1720053)
1991
40
Metastatic ovarian cystadenocarcinoma in a gilt. (2076079)
1990
41
A case of primary mucinous cystadenocarcinoma of the appendix with elevated serum carcinoembryonic antigen (CEA). (2101417)
1990
42
Imaging diagnosis of bile duct cystadenocarcinoma. (3276394)
1988
43
A case of mucinous cystadenocarcinoma of the ovary associated with virilization: pre and post-operative steroid plasma levels. (2933445)
1985
44
Collision tumors: papillary mucinous cystadenocarcinoma of ovary and endometrial carcinoma. (312422)
1979
45
Bullous pemphigoid and ovarian cystadenocarcinoma. Immunologic studies. (78684)
1978
46
Detection of tumor-specific antigens in human mucinous cystadenocarcinoma of the ovary by immunodiffusion. (13019)
1976
47
An immunologic comparison between serous cystadenocarcinoma of the ovary and other human gynecologic tumors. (4126800)
1973
48
Immunologic studies of human serous cystadenocarcinoma of ovary. Demonstration of tumor-associated antigens. (4632680)
1973
49
Antigenicity of papillary serous cystadenocarcinoma tissue culture cells. (4970936)
1968
50
Papillary cystadenocarcinoma of the ovary. (13490866)
1957

Genetic Variations for Cystadenocarcinoma

About this section

Expression for genes affiliated with Cystadenocarcinoma

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Cystadenocarcinoma

Search GEO for disease gene expression data for Cystadenocarcinoma.

Pathways for genes affiliated with Cystadenocarcinoma

About this section
Sources:
37NCBI BioSystems Database, 53Reactome, 29KEGG
See all sources

Pathways related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.3ESR2, FSHR, PGR
2
Hide members
10.3MUC1, MUC16, MUC2
310.2AKT1, AMY1A, AMY1B, AMY1C
4
Hide members
10.1AMY1C, AMY1B, AMY1A, GAST

Compounds for genes affiliated with Cystadenocarcinoma

About this section
Sources:
44Novoseek, 49PharmGKB, 28IUPHAR, 11DrugBank, 59Tocris Bioscience, 24HMDB, 2BitterDB
See all sources

Compounds related to Cystadenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 69)
idCompoundScoreTop Affiliating Genes
1estrogen4410.9CEACAM7
2butyrate4410.8CEACAM7
3sialic acid4410.7CEACAM3, FSHR
4cycloheximide4410.7CEACAM7
5dexamethasone44 49 28 1113.7AKT1, MUC2, MUC16, BIRC5
6mucicarmine4410.6CEACAM3, CEACAM7, MUC1, VIM
7metronidazole44 1111.6GAST, MUC1, CEACAM3
84-hydroxytamoxifen4410.6VIM, AKT1, ESR2, PGR
9progestin4410.6ESR2, PGR, MUC1, VIM
10dtpa4410.6GAST, MUC1, CEACAM3
11hematoxylin4410.6VIM, MUC2, MUC16, MUC1, CEACAM3
12b 7234410.6MUC1, CEACAM3, CEACAM7, MUC16, VIM
13creatinine4410.6GAST, MUC16, CEACAM3
14resveratrol44 59 11 2413.6GAST, PGR
15mifepristone44 59 28 1113.6ESR2, BIRC5, MUC1, PGR
16gefitinib44 49 1112.6ESR2, CEACAM7, AKT1, VIM, BIRC5
17crcs4410.6MUC1, BIRC5, MUC2
18agar4410.5BIRC5, PGR, AKT1, VIM, MUC1
19adriamycin4410.5PGR, MUC1, CEACAM3, BIRC5, VIM, AKT1
20dmso4410.5MUC2, ESR2, BIRC5, VIM, MUC1, PGR
21thymidylate4410.5CEACAM3, ESR2, BIRC5, VIM
22methotrexate44 49 1112.5PGR, MUC1, BIRC5, CEACAM3, MUC2, VIM
23paclitaxel44 49 1112.5PGR, BIRC5, MUC16, AKT1
245fluorouracil4410.5PGR, MUC2, MUC1, CEACAM3, CEACAM7, BIRC5
25gnrh4410.5ESR2, PGR, FSHR, GAST, VIM, AKT1
26tamoxifen44 49 28 1113.5BIRC5, CEACAM3, ESR2, VIM, AKT1, MUC1
27estradiol44 11 2412.5PGR, VIM, MUC16, MUC1, BIRC5, FSHR
28actinomycin d4410.5MUC2, BIRC5, ESR2, CEACAM7, MUC1, AKT1
29dihydrotestosterone44 28 11 2413.5ESR2, VIM, MUC1, PGR
30sb 20358044 5911.5BIRC5, MUC2, GAST, VIM, AKT1
31doxorubicin44 49 1112.4MUC16, PGR, BIRC5, CEACAM3, ESR2, AKT1
32thymidine44 2411.4CEACAM3, FSHR, MUC1, GAST, CEACAM7, BIRC5
33adenylate4410.4VIM, PGR, AKT1, GAST, FSHR, ESR2
34steroid4410.4CEACAM3, FSHR, BIRC5, MUC16
35retinoic acid44 2411.4BIRC5, VIM, AKT1, MUC2, MUC1, PGR
36paraffin4410.4MUC2, MUC1, BIRC5, ESR2, AKT1, VIM
37thyroxine44 2411.3PGR, CEACAM7, CEACAM3, GAST
38testosterone44 59 11 2413.3ESR2, MUC16, MUC1, BIRC5, PGR, FSHR
39alanine4410.3FSHR, BIRC5, PGR, GAST, VIM, AKT1
40vegf4410.3MUC1, PGR, BIRC5, ESR2, CEACAM3, MUC16
415-aza-2deoxycytidine4410.3VIM, MUC2, PGR, ESR2
42cysteine4410.3FSHR, PGR, VIM, AKT1, MUC1, MUC2
43progesterone44 59 28 11 2414.3CEACAM3, VIM, MUC2, MUC16, MUC1, PGR
44genistein44 28 59 2 11 2415.3VIM, AKT1, PGR, BIRC5, ESR2
45serine4410.3BIRC5, MUC1, MUC16, MUC2, AKT1, GAST
46indium4410.2CEACAM3, MUC1
47folate4410.2PGR, MUC1, GAST, VIM
48glucose4410.2AKT1, MUC2, CEACAM3, BIRC5, MUC16, MUC1
49threonine4410.1AKT1, FSHR, MUC1, MUC16, MUC2, BIRC5
50fundal4410.0GAST, PGR

GO Terms for genes affiliated with Cystadenocarcinoma

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:00579610.3MUC1, MUC16, MUC2

Biological processes related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1O-glycan processingGO:01626610.3MUC1, MUC16, MUC2

Molecular functions related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1enzyme bindingGO:01989910.2ESR2, BIRC5, PGR, AKT1
2protein bindingGO:0055159.1ESR2, VIM, AMY1C, UBE4A, GAST, USP14

Products for genes affiliated with Cystadenocarcinoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cystadenocarcinoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet