MCID: CYS014
MIFTS: 54

Cystadenocarcinoma malady

Cancer diseases category
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Summaries for Cystadenocarcinoma

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8Disease Ontology, 65Wikipedia, 33MalaCards
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Disease Ontology:8 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, in which cystic accumulations of retained secretions are formed.

MalaCards: Cystadenocarcinoma, also known as cystadenocarcinoma nos, is related to ovarian mucinous cystadenocarcinoma and cystadenoma. An important gene associated with Cystadenocarcinoma is MUC1 (mucin 1, cell surface associated), and among its related pathways are O-linked glycosylation of mucins and EGFR Signaling Pathway. The compounds eosin and s 100 have been mentioned in the context of this disorder. Affiliated tissues include ovary, pancreas and appendix, and related mouse phenotypes are muscle and integument.

Wikipedia:65 Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from... more...

Aliases & Classifications for Cystadenocarcinoma

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8Disease Ontology, 45Novoseek, 62UMLS, 40NCIt, 35MeSH, 58SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

cystadenocarcinoma 8 45 62
cystadenocarcinoma nos 8


External Ids:

Disease Ontology8 DOID:3111
NCIt40 C2971
SNOMED-CT58 189681005, 21008007
MeSH35 D003536

Related Diseases for Cystadenocarcinoma

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17GeneCards, 18GeneDecks
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Diseases related to Cystadenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 155)
idRelated DiseaseScoreTop Affiliating Genes
1ovarian mucinous cystadenocarcinoma31.2FSHR
2cystadenoma31.2FSHR
3pseudomyxoma peritonei30.8MUC2
4giant cell tumor30.4MUC1, VIM
5adenocarcinoma30.2ESR2, VIM, MUC2, MUC1, FSHR, AKT1
6papillary adenocarcinoma30.2MUC2, MUC1
7angiosarcoma29.9VIM, MUC1
8ovarian cancer29.9ESR2, MUC2, BIRC5, PGR, MUC1
9adenosquamous carcinoma29.9MUC2, PGR, MUC1
10leiomyosarcoma29.9PGR, VIM, MUC1
11cholangiocarcinoma29.8MUC1, MUC2
12endometriosis29.8ESR2, PGR, FSHR
13pancreatic cancer29.8BIRC5, AKT1, MUC2
14leiomyoma29.8VIM, PGR, ESR2
15endometrial carcinoma29.8AKT1, ESR2, PGR
16colon cancer29.7AKT1, BIRC5, ESR2, MUC2
17adenoma29.7MUC2, MUC1, FSHR, BIRC5, ESR2
18mucinous cystadenocarcinoma11.1
19serous cystadenocarcinoma10.9
20papillary cystadenocarcinoma10.8
21pancreatitis10.7
22ovarian cystadenocarcinoma10.6
23pancreatic cystadenocarcinoma10.5
24ovarian serous cystadenocarcinoma10.5
25peritonitis10.5
26hepatitis10.5
27acinar cell cystadenocarcinoma10.4
28teratoma10.3
29pancreatic serous cystadenocarcinoma10.3
30bile duct cystadenocarcinoma10.3
31zollinger-ellison syndrome10.3
32cystic teratoma10.3
33prostatitis10.3
34sarcoma10.3
35appendix mucinous cystadenocarcinoma10.2
36pancreatic cystadenoma10.2
37pancreatic non-invasive mucinous cystadenocarcinoma10.1
38ovarian clear cell cystadenocarcinoma10.1
39multilocular clear cell renal cell carcinoma10.1
40breast mucinous cystadenocarcinoma10.1
41hidradenoma10.1MUC1
42syringoma10.1MUC1
43progesterone resistance10.1PGR
44biliary papillomatosis10.1MUC2
45adenomatoid tumor10.1VIM
46glomus tumor10.1VIM
47mammary paget's disease10.1MUC1, PGR
48sertoli-leydig cell tumor10.1MUC1, PGR
49secretory meningioma10.1MUC1, VIM
50clear cell ependymoma10.1VIM, MUC1

Graphical network of the top 20 diseases related to Cystadenocarcinoma:



Diseases related to cystadenocarcinoma

Symptoms for Cystadenocarcinoma

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Drugs & Therapeutics for Cystadenocarcinoma

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Cystadenocarcinoma

Search NIH Clinical Center for Cystadenocarcinoma

Genetic Tests for Cystadenocarcinoma

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Anatomical Context for Cystadenocarcinoma

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33MalaCards
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MalaCards organs/tissues related to Cystadenocarcinoma:

33
Ovary, Pancreas, Appendix, Liver, Salivary gland, Colon, Breast, Lymph node, Prostate, Testis, Lung, Spleen, Kidney, Tongue, Skin, Testes, Bone, Eye, Cervix, Endothelial, Thyroid

Animal Models for Cystadenocarcinoma or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Cystadenocarcinoma:

37 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.2AKT1, VIM, ESR2, PGR
2MP:00107718.1PGR, ESR2, MUC1, FSHR, AKT1
3MP:00020067.8AKT1, PGR, ESR2, MUC2, MUC1, FSHR
4MP:00028737.8BIRC5, AKT1, MUC1, ESR2, PGR
5MP:00053897.7PGR, ESR2, VIM, FSHR, AKT1
6MP:00053797.7PGR, ESR2, MUC2, MUC1, FSHR, AKT1
7MP:00053867.5PGR, ESR2, VIM, FSHR, AKT1
8MP:00053857.5PGR, ESR2, VIM, MUC2, FSHR, AKT1
9MP:00053977.0PGR, ESR2, VIM, MUC2, FSHR, AKT1
10MP:00053877.0PGR, ESR2, VIM, MUC2, FSHR, AKT1
11MP:00053846.9PGR, ESR2, VIM, MUC2, FSHR, AKT1
12MP:00107686.9PGR, ESR2, VIM, MUC2, FSHR, AKT1
13MP:00053766.7PGR, ESR2, VIM, MUC2, MUC1, FSHR

Publications for Cystadenocarcinoma

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Sources:
52PubMed
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Articles related to Cystadenocarcinoma:

(show top 50)    (show all 591)
idTitleAuthorsYear
1
Papillary cystadenocarcinoma of the mammary gland with metastases to the gastrointestinal tract in a Himalayan brown bear (Ursus arctos). (23805565)
2013
2
Serous papillary cystadenocarcinoma in supernumerary ovary. (23550880)
2013
3
Cytomorphological findings and histological correlation of low-grade cribriform cystadenocarcinoma of salivary gland in fine-needle aspiration: a case study. (24421856)
2013
4
Peritoneal papillary serous cystadenocarcinoma at a previous laparoscopic trocar site. (23040941)
2012
5
Successful surgical management of an extrahepatic biliary cystadenocarcinoma. (22355491)
2011
6
Primary retroperitoneal mucinous cystadenocarcinoma: a case report and review of the literature. (20558993)
2010
7
Successful left hemihepatectomy and perioperative management of a patient with biliary cystadenocarcinoma, complicated with MELAS syndrome: report of a case. (20740354)
2010
8
Cytological features of cystadenocarcinoma in cyst fluid of the parotid gland: Diagnostic pitfalls and literature review. (19927358)
2010
9
Biliary cystadenocarcinoma of the gall bladder: a case report. (19946551)
2009
10
Huge liver abscess radiologically mimicking cystadenocarcinoma. (19725434)
2009
11
Gingival metastasis from ovarian mucinous cystadenocarcinoma as an initial manifestation (a rare case report). (19246966)
2008
12
Papillary cystadenocarcinoma of the prostate: a case report. (17310773)
2007
13
Mucinous cystadenocarcinoma of the pancreas developing during hormone replacement therapy. (17372823)
2007
14
Cystadenocarcinoma of salivary gland presenting as a cystic lesion in the mandible. (16448922)
2006
15
Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma. (17007033)
2006
16
Mucinous cystadenocarcinoma--an extremely rare tumor in a young patient. (16639689)
2006
17
Peritoneal mucinous cystadenocarcinoma of probable urachal origin: a challenging diagnosis. (17021133)
2006
18
Mammary mucinous cystadenocarcinoma. (17163855)
2006
19
Acinar cell cystadenocarcinoma of the pancreas: report of rare case and review of the literature. (15619219)
2004
20
Biliary cystadenocarcinoma associated with atrophy of the left hepatic lobe and hepatolithiasis mimicking intrahepatic cholangiocarcinoma: a case report. (15191223)
2004
21
Plasma cell leukaemia with papillary serous cystadenocarcinoma of ovary--a case report. (15025299)
2003
22
Giant mucinous cystadenocarcinoma: a case report. (12552327)
2003
23
Co-existent ovarian mucinous cystadenocarcinoma and ovarian choriocarcinoma. (12192487)
2002
24
Treatment of a case of primary retroperitoneal mucinous cystadenocarcinoma: is adjuvant hysterectomy and bilateral salpingo-oophorectomy justified? (12114915)
2002
25
DIC-CT findings of biliary cystadenocarcinoma communicating with the bile duct: a case report. (11490785)
2001
26
Renal microcystic tubular lesions in two 1Year-old dogs - an early sign of hereditary renal cystadenocarcinoma? (11032680)
2000
27
Estrogen receptor alpha (ER-alpha) and beta (ER-beta) mRNAs in normal ovary, ovarian serous cystadenocarcinoma and ovarian cancer cell lines: down-regulation of ER-beta in neoplastic tissues. (9506768)
1998
28
Serous cystadenocarcinoma and ovarian teratoma during pregnancy. (8737305)
1996
29
Primary retroperitoneal mucinous cystadenocarcinoma of low malignant potential: a case report and literature review. (8626105)
1996
30
Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. (7644647)
1995
31
Liver metastases from ovarian cystadenocarcinoma masquerading on CT as lobar fatty infiltration. (8370842)
1993
32
Mucinous cystadenocarcinoma of the pancreas with liver metastases. An unusual presentation of a rare tumor. (8239476)
1993
33
Immuno-histological characterization of OVS1 and OVS2 monoclonal antibodies recognizing human ovarian mucinous cystadenocarcinoma. (1284830)
1992
34
Cystadenocarcinoma of the pancreas: neo-adjuvant therapy and CEA monitoring. (2296199)
1990
35
Primary retroperitoneal mucinous cystadenocarcinoma: report of a case. (2075232)
1990
36
Mucinous cystadenocarcinoma of the appendix. A rare tumor of the right iliac fossa]. (2262520)
1990
37
Hyperamylasemia with papillary serous cystadenocarcinoma of the ovary. (2482644)
1989
38
Unique appearance of the duodenal papilla in pancreatic cystadenocarcinoma. (2539985)
1989
39
Cystadenocarcinoma versus pseudocyst of the pancreas: a difficult differential diagnosis. (2666031)
1989
40
Papillary cystadenocarcinoma of the appendiceal stump with mucocele and peritoneal metastases. (2812872)
1989
41
Simultaneous occurrence of a granulosa cell tumour and a serous papillary cystadenocarcinoma in the same ovary. A case report. (4036607)
1985
42
Papillary cystadenocarcinoma of the prostate. (6708240)
1984
43
Spontaneous papillary cystadenocarcinoma of the ovary in Dunkin-Hartley guineapigs. (7359885)
1980
44
Metastatic, papillary cystadenocarcinoma of the mammary gland in a black-footed ferret. (7463613)
1980
45
Intratesticular papillary mucinous cystadenocarcinoma. (483506)
1979
46
Classification and survival rate of patients with serous cystadenocarcinoma of the ovaries. (1004656)
1976
47
An autopsy case of mucinous cystadenocarcinoma of the liver. (1025932)
1976
48
An immunologic comparison between serous cystadenocarcinoma of the ovary and other human gynecologic tumors. (4126800)
1973
49
Papillary cystadenocarcinoma of the pancreas; case report. (12986668)
1952
50
Calcified metastatic deposits in the peritoneal cavity, liver and right lung field from papillary cystadenocarcinoma of the ovary. (14771326)
1950

Variations for Cystadenocarcinoma

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Expression for genes affiliated with Cystadenocarcinoma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cystadenocarcinoma

Search GEO for disease gene expression data for Cystadenocarcinoma.

Pathways for genes affiliated with Cystadenocarcinoma

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50PathCards, 55Reactome, 30KEGG, 57SinoBiological, 38NCBI BioSystems Database, 60Thomson Reuters, 54R&D Systems, 53QIAGEN
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Pathways related to Cystadenocarcinoma according to GeneCards/GeneDecks:

(show all 14)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7MUC1, MUC2
29.6MUC1, AKT1
39.6FSHR, AKT1
4
Show member pathways
Cell cycle ESR1 regulation of G1 S transition60
Immune response MIF JAB1 signaling60
Cell cycle Cell cycle generic schema 60
9.5AKT1, PGR
5
Show member pathways
9.4AKT1, VIM
6
Show member pathways
Signaling by Aurora kinases38
Aurora C signaling38
9.3BIRC5, VIM
79.3BIRC5, AKT1
89.3BIRC5, AKT1
9
Show member pathways
Nuclear Receptors38
9.2ESR2, PGR
109.1AKT1, ESR2
11
Show member pathways
IL-9 Signaling Pathway38
Development Thrombopoietin regulated cell processes60
IL-7 Signaling Pathway38
Immune response IL 9 signaling pathway60
9.0BIRC5, AKT1, MUC1
128.9FSHR, ESR2, PGR
13
Show member pathways
8.6AKT1, VIM, ESR2
14
Show member pathways
8.3ESR2, VIM, MUC1, AKT1

Compounds for genes affiliated with Cystadenocarcinoma

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45Novoseek, 51PharmGKB, 11DrugBank, 24HMDB, 29IUPHAR, 61Tocris Bioscience, 3BitterDB
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Compounds related to Cystadenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 113)
idCompoundScoreTop Affiliating Genes
1eosin459.8MUC1, VIM
2s 100459.6MUC1, VIM
3hematoxylin459.4MUC2, VIM, MUC1
4crcs459.4MUC2, MUC1, BIRC5
5trastuzumab45 51 1111.4PGR, MUC1, BIRC5
6nandrolone45 2410.2PGR, ESR2
7gemcitabine45 51 1111.2BIRC5, AKT1, MUC1
8trilostane45 1110.1PGR, ESR2
9nocodazole45 1110.0VIM, BIRC5, AKT1
10sialic acid459.0FSHR, MUC2, MUC1
115fluorouracil459.0PGR, MUC1, BIRC5, MUC2
12vincristine45 51 1111.0BIRC5, AKT1, VIM
13ribonucleic acid458.9ESR2, FSHR, MUC1, PGR
14progestin458.8PGR, ESR2, VIM, MUC1
15dihydrotestosterone45 29 24 1111.8PGR, MUC1, VIM, ESR2
16paclitaxel45 51 1110.7BIRC5, AKT1, VIM, PGR
17resveratrol45 61 24 1111.7PGR, BIRC5, ESR2
18thymidylate458.7ESR2, VIM, BIRC5
19sb 20358045 619.7BIRC5, MUC2, VIM, AKT1
20mifepristone45 29 61 1111.7MUC1, BIRC5, PGR, ESR2
215-aza-2deoxycytidine458.6VIM, ESR2, PGR, MUC2
224-hydroxytamoxifen458.6VIM, AKT1, ESR2, PGR
23methotrexate51 45 1110.5BIRC5, MUC2, VIM, PGR, MUC1
24adriamycin458.5VIM, PGR, AKT1, BIRC5, MUC1
25agar458.5BIRC5, AKT1, PGR, VIM, MUC1
26threonine458.5FSHR, MUC2, AKT1, MUC1, BIRC5
27butyrate458.4BIRC5, AKT1, MUC1, MUC2, VIM
28gefitinib45 51 1110.4AKT1, VIM, ESR2, BIRC5
29alanine458.3BIRC5, PGR, AKT1, VIM, FSHR
30etoposide45 51 61 1111.3BIRC5, AKT1, VIM, ESR2
31rapamycin458.3BIRC5, ESR2, VIM, AKT1
32gnrh458.2FSHR, PGR, ESR2, VIM, AKT1
33lipid458.2VIM, FSHR, MUC1, BIRC5, AKT1
34adenylate458.2AKT1, PGR, ESR2, VIM, FSHR
35doxorubicin45 51 1110.0BIRC5, PGR, AKT1, VIM, ESR2
36genistein45 29 61 3 24 1113.0VIM, ESR2, PGR, AKT1, BIRC5
37cycloheximide457.9ESR2, PGR, AKT1, VIM, BIRC5
38estradiol45 24 119.8VIM, MUC1, FSHR, BIRC5, ESR2, PGR
39dmso457.7BIRC5, MUC1, MUC2, VIM, ESR2, PGR
40tamoxifen45 51 29 1110.7AKT1, ESR2, VIM, PGR, MUC1, BIRC5
41vegf457.6PGR, ESR2, BIRC5, AKT1, MUC1, VIM
42actinomycin d457.6AKT1, ESR2, VIM, MUC2, MUC1, BIRC5
43cysteine457.4AKT1, VIM, ESR2, PGR, FSHR, MUC1
44progesterone45 29 61 24 1111.4MUC1, ESR2, VIM, MUC2, FSHR, BIRC5
45testosterone45 61 24 1110.3FSHR, PGR, ESR2, VIM, MUC1, AKT1
46paraffin457.2PGR, MUC1, MUC2, VIM, ESR2, BIRC5
47dexamethasone45 51 29 1110.2BIRC5, AKT1, MUC1, VIM, ESR2, PGR
48serine457.2FSHR, VIM, AKT1, MUC1, MUC2, BIRC5
49retinoic acid45 248.2ESR2, VIM, MUC2, PGR, MUC1, AKT1
50estrogen456.9AKT1, PGR, ESR2, VIM, BIRC5, MUC1

GO Terms for genes affiliated with Cystadenocarcinoma

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16Gene Ontology
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Biological processes related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1O-glycan processingGO:0162669.4MUC1, MUC2
2negative regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:0431549.3BIRC5, AKT1
3uterus developmentGO:0600659.2FSHR, ESR2

Molecular functions related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1steroid bindingGO:0054969.2ESR2, PGR
2ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activityGO:0048799.1PGR, ESR2
3steroid hormone receptor activityGO:0037078.9ESR2, PGR
4identical protein bindingGO:0428028.8BIRC5, AKT1, VIM
5enzyme bindingGO:0198998.2BIRC5, AKT1, ESR2, PGR
6protein bindingGO:0055156.5PGR, ESR2, VIM, MUC2, MUC1, FSHR

Products for genes affiliated with Cystadenocarcinoma

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Sources for Cystadenocarcinoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet