MCID: CYS014
MIFTS: 46

Cystadenocarcinoma malady

Summaries for Cystadenocarcinoma

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Disease Ontology:9 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, in which cystic accumulations of retained secretions are formed.

MalaCards based summary: Cystadenocarcinoma, also known as cystadenocarcinoma nos, is related to ovarian mucinous cystadenocarcinoma and cystadenoma. An important gene associated with Cystadenocarcinoma is MUC1 (mucin 1, cell surface associated), and among its related pathways are O-linked glycosylation of mucins and EGFR Signaling Pathway. The compounds eosin and s 100 have been mentioned in the context of this disorder. Affiliated tissues include ovary, pancreas and liver, and related mouse phenotypes are muscle and integument.

Wikipedia:63 Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from... more...

Aliases & Classifications for Cystadenocarcinoma

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Sources:
9Disease Ontology, 43Novoseek, 60UMLS, 55SNOMED-CT, 38NCIt, 33MeSH
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Cystadenocarcinoma, Aliases & Descriptions:

Name: Cystadenocarcinoma 9 43 60
 
Cystadenocarcinoma Nos 9


External Ids:

Disease Ontology9 DOID:3111
NCIt38 C2971
SNOMED-CT55 21008007, 189681005
MeSH33 D003536

Related Diseases for Cystadenocarcinoma

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Diseases related to Cystadenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 158)
idRelated DiseaseScoreTop Affiliating Genes
1ovarian mucinous cystadenocarcinoma31.8FSHR
2cystadenoma31.8FSHR
3pseudomyxoma peritonei31.3MUC2
4giant cell tumor30.8VIM, MUC1
5papillary adenocarcinoma30.5MUC2, MUC1
6mesothelioma30.3MUC1, VIM
7angiosarcoma30.2VIM, MUC1
8adenosquamous carcinoma30.1PGR, MUC2, MUC1
9leiomyosarcoma30.0PGR, VIM, MUC1
10cholangiocarcinoma29.8MUC1, MUC2
11endometriosis29.8FSHR, ESR2, PGR
12pancreatic cancer29.8MUC2, AKT1, BIRC5
13leiomyoma29.7VIM, ESR2, PGR
14adenoma29.1ESR2, MUC2, MUC1, FSHR, BIRC5
15adenocarcinoma29.0PGR, ESR2, VIM, MUC2, MUC1, FSHR
16mucinous cystadenocarcinoma11.1
17serous cystadenocarcinoma10.9
18papillary cystadenocarcinoma10.9
19pancreatitis10.7
20ovarian cystadenocarcinoma10.7
21pancreatic cystadenocarcinoma10.6
22ovarian serous cystadenocarcinoma10.5
23hidradenoma10.5MUC1
24peritonitis10.5
25syringoma10.5MUC1
26progesterone resistance10.5PGR
27hepatitis10.5
28biliary papillomatosis10.5MUC2
29adenomatoid tumor10.4VIM
30glomus tumor10.4VIM
31acinar cell cystadenocarcinoma10.4
32teratoma10.3
33mammary paget's disease10.3PGR, MUC1
34sertoli-leydig cell tumor10.3PGR, MUC1
35bile duct cystadenocarcinoma10.3
36pancreatic serous cystadenocarcinoma10.3
37secretory meningioma10.3MUC1, VIM
38clear cell ependymoma10.3MUC1, VIM
39mesenchymal chondrosarcoma10.3VIM, MUC1
40zollinger-ellison syndrome10.3
41cystic teratoma10.3
42prostatitis10.3
43sarcoma10.3
44spindle cell sarcoma10.3VIM, MUC1
45epithelioid sarcoma10.3MUC1, VIM
46dermatofibrosarcoma protuberans10.3MUC1, VIM
47rhabdoid tumor10.3VIM, MUC1
48perineurioma10.3VIM, MUC1
49hemangiopericytoma10.3MUC1, VIM
50malignant mixed mullerian tumor10.3VIM, PGR

Graphical network of the top 20 diseases related to Cystadenocarcinoma:



Diseases related to cystadenocarcinoma

Symptoms for Cystadenocarcinoma

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Drugs & Therapeutics for Cystadenocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Cystadenocarcinoma

Search NIH Clinical Center for Cystadenocarcinoma

Genetic Tests for Cystadenocarcinoma

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Anatomical Context for Cystadenocarcinoma

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MalaCards organs/tissues related to Cystadenocarcinoma:

31
Ovary, Pancreas, Liver, Appendix, Breast, Salivary gland, Colon, Lymph node, Prostate, Testis, Kidney, Lung, Spleen, Skin, Tongue, Eye, Bone, Testes, Small intestine, Thyroid, Cervix, Endothelial

Animal Models for Cystadenocarcinoma or affiliated genes

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MGI Mouse Phenotypes related to Cystadenocarcinoma:

35 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.2AKT1, VIM, ESR2, PGR
2MP:00107718.1PGR, ESR2, MUC1, FSHR, AKT1
3MP:00020067.8AKT1, PGR, ESR2, MUC2, MUC1, FSHR
4MP:00028737.8BIRC5, AKT1, MUC1, ESR2, PGR
5MP:00053897.7PGR, ESR2, VIM, FSHR, AKT1
6MP:00053797.7PGR, ESR2, MUC2, MUC1, FSHR, AKT1
7MP:00053867.5PGR, ESR2, VIM, FSHR, AKT1
8MP:00053857.5PGR, ESR2, VIM, MUC2, FSHR, AKT1
9MP:00053977.0PGR, ESR2, VIM, MUC2, FSHR, AKT1
10MP:00053877.0PGR, ESR2, VIM, MUC2, FSHR, AKT1
11MP:00053846.9PGR, ESR2, VIM, MUC2, FSHR, AKT1
12MP:00107686.9PGR, ESR2, VIM, MUC2, FSHR, AKT1
13MP:00053766.7PGR, ESR2, VIM, MUC2, MUC1, FSHR

Publications for Cystadenocarcinoma

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Articles related to Cystadenocarcinoma:

(show top 50)    (show all 617)
idTitleAuthorsYear
1
Paratesticular papillary serous cystadenocarcinoma: A rare entity in Indian population. (25308020)
2014
2
Primary mucinous cystadenocarcinoma of the breast with amplification of the HER2 gene confirmed by FISH - case report and review of the literature. (25119013)
2014
3
Papillary cystadenocarcinoma of the mammary gland with metastases to the gastrointestinal tract in a Himalayan brown bear (Ursus arctos). (23805565)
2013
4
Serous papillary cystadenocarcinoma in supernumerary ovary. (23550880)
2013
5
Cytomorphological findings and histological correlation of low-grade cribriform cystadenocarcinoma of salivary gland in fine-needle aspiration: a case study. (24421856)
2013
6
Peritoneal papillary serous cystadenocarcinoma at a previous laparoscopic trocar site. (23040941)
2012
7
Successful surgical management of an extrahepatic biliary cystadenocarcinoma. (22355491)
2011
8
Successful left hemihepatectomy and perioperative management of a patient with biliary cystadenocarcinoma, complicated with MELAS syndrome: report of a case. (20740354)
2010
9
Cytological features of cystadenocarcinoma in cyst fluid of the parotid gland: Diagnostic pitfalls and literature review. (19927358)
2010
10
Biliary cystadenocarcinoma of the gall bladder: a case report. (19946551)
2009
11
Huge liver abscess radiologically mimicking cystadenocarcinoma. (19725434)
2009
12
Gingival metastasis from ovarian mucinous cystadenocarcinoma as an initial manifestation (a rare case report). (19246966)
2008
13
Papillary cystadenocarcinoma of the prostate: a case report. (17310773)
2007
14
Mucinous cystadenocarcinoma of the pancreas developing during hormone replacement therapy. (17372823)
2007
15
Cystadenocarcinoma of salivary gland presenting as a cystic lesion in the mandible. (16448922)
2006
16
Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma. (17007033)
2006
17
Mucinous cystadenocarcinoma--an extremely rare tumor in a young patient. (16639689)
2006
18
Peritoneal mucinous cystadenocarcinoma of probable urachal origin: a challenging diagnosis. (17021133)
2006
19
Mammary mucinous cystadenocarcinoma. (17163855)
2006
20
Acinar cell cystadenocarcinoma of the pancreas: report of rare case and review of the literature. (15619219)
2004
21
Biliary cystadenocarcinoma associated with atrophy of the left hepatic lobe and hepatolithiasis mimicking intrahepatic cholangiocarcinoma: a case report. (15191223)
2004
22
Plasma cell leukaemia with papillary serous cystadenocarcinoma of ovary--a case report. (15025299)
2003
23
Giant mucinous cystadenocarcinoma: a case report. (12552327)
2003
24
Co-existent ovarian mucinous cystadenocarcinoma and ovarian choriocarcinoma. (12192487)
2002
25
Treatment of a case of primary retroperitoneal mucinous cystadenocarcinoma: is adjuvant hysterectomy and bilateral salpingo-oophorectomy justified? (12114915)
2002
26
DIC-CT findings of biliary cystadenocarcinoma communicating with the bile duct: a case report. (11490785)
2001
27
Renal microcystic tubular lesions in two 1Year-old dogs - an early sign of hereditary renal cystadenocarcinoma? (11032680)
2000
28
Estrogen receptor alpha (ER-alpha) and beta (ER-beta) mRNAs in normal ovary, ovarian serous cystadenocarcinoma and ovarian cancer cell lines: down-regulation of ER-beta in neoplastic tissues. (9506768)
1998
29
Serous cystadenocarcinoma and ovarian teratoma during pregnancy. (8737305)
1996
30
Primary retroperitoneal mucinous cystadenocarcinoma of low malignant potential: a case report and literature review. (8626105)
1996
31
Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. (7644647)
1995
32
Liver metastases from ovarian cystadenocarcinoma masquerading on CT as lobar fatty infiltration. (8370842)
1993
33
Mucinous cystadenocarcinoma of the pancreas with liver metastases. An unusual presentation of a rare tumor. (8239476)
1993
34
Immuno-histological characterization of OVS1 and OVS2 monoclonal antibodies recognizing human ovarian mucinous cystadenocarcinoma. (1284830)
1992
35
Cystadenocarcinoma of the pancreas: neo-adjuvant therapy and CEA monitoring. (2296199)
1990
36
Primary retroperitoneal mucinous cystadenocarcinoma: report of a case. (2075232)
1990
37
Mucinous cystadenocarcinoma of the appendix. A rare tumor of the right iliac fossa]. (2262520)
1990
38
Hyperamylasemia with papillary serous cystadenocarcinoma of the ovary. (2482644)
1989
39
Unique appearance of the duodenal papilla in pancreatic cystadenocarcinoma. (2539985)
1989
40
Cystadenocarcinoma versus pseudocyst of the pancreas: a difficult differential diagnosis. (2666031)
1989
41
Simultaneous occurrence of a granulosa cell tumour and a serous papillary cystadenocarcinoma in the same ovary. A case report. (4036607)
1985
42
Papillary cystadenocarcinoma of the prostate. (6708240)
1984
43
Spontaneous papillary cystadenocarcinoma of the ovary in Dunkin-Hartley guineapigs. (7359885)
1980
44
Metastatic, papillary cystadenocarcinoma of the mammary gland in a black-footed ferret. (7463613)
1980
45
Intratesticular papillary mucinous cystadenocarcinoma. (483506)
1979
46
Classification and survival rate of patients with serous cystadenocarcinoma of the ovaries. (1004656)
1976
47
An autopsy case of mucinous cystadenocarcinoma of the liver. (1025932)
1976
48
An immunologic comparison between serous cystadenocarcinoma of the ovary and other human gynecologic tumors. (4126800)
1973
49
Papillary cystadenocarcinoma of the pancreas; case report. (12986668)
1952
50
Calcified metastatic deposits in the peritoneal cavity, liver and right lung field from papillary cystadenocarcinoma of the ovary. (14771326)
1950

Variations for Cystadenocarcinoma

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Expression for genes affiliated with Cystadenocarcinoma

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Search GEO for disease gene expression data for Cystadenocarcinoma.

Pathways for genes affiliated with Cystadenocarcinoma

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Pathways related to Cystadenocarcinoma according to GeneCards Suite gene sharing:

(show all 14)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7MUC1, MUC2
29.6MUC1, AKT1
39.6FSHR, AKT1
4
Show member pathways
Cell cycle ESR1 regulation of G1 S transition58
Immune response MIF JAB1 signaling58
Cell cycle Cell cycle generic schema 58
9.5AKT1, PGR
5
Show member pathways
9.4AKT1, VIM
6
Show member pathways
Signaling by Aurora kinases36
Aurora C signaling36
9.3BIRC5, VIM
79.3BIRC5, AKT1
89.3BIRC5, AKT1
9
Show member pathways
Nuclear Receptors36
9.2ESR2, PGR
109.1AKT1, ESR2
11
Show member pathways
IL-9 Signaling Pathway36
Development Thrombopoietin regulated cell processes58
IL-7 Signaling Pathway36
Immune response IL 9 signaling pathway58
9.0BIRC5, AKT1, MUC1
128.9FSHR, ESR2, PGR
13
Show member pathways
8.6AKT1, VIM, ESR2
14
Show member pathways
8.3ESR2, VIM, MUC1, AKT1

Compounds for genes affiliated with Cystadenocarcinoma

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Compounds related to Cystadenocarcinoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 113)
idCompoundScoreTop Affiliating Genes
1eosin439.8MUC1, VIM
2s 100439.6MUC1, VIM
3hematoxylin439.4MUC2, MUC1, VIM
4crcs439.4MUC2, MUC1, BIRC5
5trastuzumab43 49 1211.4BIRC5, MUC1, PGR
6estradiol benzoate439.2PGR, ESR2
7gemcitabine43 49 1211.2BIRC5, AKT1, MUC1
8trilostane43 1210.1ESR2, PGR
9nocodazole43 1210.0AKT1, VIM, BIRC5
10sialic acid439.0MUC1, MUC2, FSHR
115fluorouracil439.0MUC2, MUC1, BIRC5, PGR
12vincristine43 49 1211.0BIRC5, AKT1, VIM
13ribonucleic acid438.9FSHR, PGR, ESR2, MUC1
14progestin438.8PGR, ESR2, VIM, MUC1
15dihydrotestosterone43 28 24 1211.8PGR, MUC1, VIM, ESR2
16paclitaxel43 49 1210.7BIRC5, AKT1, VIM, PGR
17resveratrol43 59 24 1211.7BIRC5, PGR, ESR2
18thymidylate438.7VIM, BIRC5, ESR2
19sb 20358043 599.7AKT1, MUC2, VIM, BIRC5
20mifepristone43 28 59 1211.7PGR, BIRC5, ESR2, MUC1
215-aza-2deoxycytidine438.6ESR2, PGR, VIM, MUC2
224-hydroxytamoxifen438.6VIM, AKT1, ESR2, PGR
23methotrexate49 43 1210.5BIRC5, MUC2, VIM, PGR, MUC1
24adriamycin438.5VIM, PGR, AKT1, BIRC5, MUC1
25agar438.5BIRC5, AKT1, PGR, VIM, MUC1
26threonine438.5MUC2, BIRC5, MUC1, AKT1, FSHR
27butyrate438.4BIRC5, AKT1, MUC1, MUC2, VIM
28gefitinib43 49 1210.4AKT1, VIM, ESR2, BIRC5
29alanine438.3FSHR, BIRC5, PGR, VIM, AKT1
30etoposide43 49 59 1211.3AKT1, BIRC5, VIM, ESR2
31rapamycin438.3AKT1, ESR2, VIM, BIRC5
32gnrh438.2FSHR, PGR, ESR2, VIM, AKT1
33lipid438.2AKT1, VIM, MUC1, BIRC5, FSHR
34adenylate438.2AKT1, PGR, ESR2, VIM, FSHR
35doxorubicin43 49 1210.0BIRC5, PGR, AKT1, VIM, ESR2
36genistein43 28 59 2 24 1213.0VIM, ESR2, PGR, AKT1, BIRC5
37cycloheximide437.9ESR2, BIRC5, AKT1, VIM, PGR
38estradiol43 24 129.8VIM, MUC1, FSHR, BIRC5, ESR2, PGR
39dmso437.7BIRC5, MUC1, MUC2, VIM, ESR2, PGR
40tamoxifen43 49 28 1210.7AKT1, ESR2, VIM, PGR, MUC1, BIRC5
41vegf437.6PGR, ESR2, BIRC5, AKT1, MUC1, VIM
42actinomycin d437.6AKT1, ESR2, VIM, MUC2, MUC1, BIRC5
43cysteine437.4AKT1, VIM, ESR2, PGR, FSHR, MUC1
44progesterone43 28 59 24 1211.4MUC1, ESR2, VIM, MUC2, FSHR, BIRC5
45testosterone43 59 24 1210.3FSHR, PGR, ESR2, VIM, MUC1, AKT1
46paraffin437.2PGR, MUC1, MUC2, VIM, ESR2, BIRC5
47dexamethasone43 49 28 1210.2BIRC5, AKT1, MUC1, VIM, ESR2, PGR
48serine437.2FSHR, VIM, AKT1, MUC1, MUC2, BIRC5
49retinoic acid43 248.2ESR2, VIM, MUC2, PGR, MUC1, AKT1
50estrogen436.9AKT1, PGR, ESR2, VIM, BIRC5, MUC1

GO Terms for genes affiliated with Cystadenocarcinoma

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Biological processes related to Cystadenocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1O-glycan processingGO:00162669.4MUC1, MUC2
2negative regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:00431549.3BIRC5, AKT1
3uterus developmentGO:00600659.2FSHR, ESR2

Molecular functions related to Cystadenocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1steroid bindingGO:00054969.2ESR2, PGR
2ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activityGO:00048799.1PGR, ESR2
3steroid hormone receptor activityGO:00037078.9ESR2, PGR
4identical protein bindingGO:00428028.8BIRC5, AKT1, VIM
5enzyme bindingGO:00198998.2BIRC5, AKT1, ESR2, PGR
6protein bindingGO:00055156.5PGR, ESR2, VIM, MUC2, MUC1, FSHR

Products for genes affiliated with Cystadenocarcinoma

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Sources for Cystadenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet