MCID: CYS014
MIFTS: 52

Cystadenocarcinoma malady

Summaries for Cystadenocarcinoma

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, in which cystic accumulations of retained secretions are formed.

MalaCards: Cystadenocarcinoma, also known as cystadenocarcinoma nos, is related to mucinous cystadenocarcinoma and ovarian mucinous cystadenocarcinoma. An important gene associated with Cystadenocarcinoma is FSHR (follicle stimulating hormone receptor), and among its related pathways are Ovarian Infertility Genes and O-linked glycosylation of mucins. The compounds estrogen and butyrate have been mentioned in the context of this disorder. Affiliated tissues include ovary, pancreas and appendix, and related mouse phenotypes are homeostasis/metabolism and tumorigenesis.

Wikipedia:63 Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from... more...

Aliases & Classifications for Cystadenocarcinoma

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8Disease Ontology, 44Novoseek, 60UMLS, 39NCIt, 34MeSH, 56SNOMED-CT
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Aliases & Descriptions:

cystadenocarcinoma 8 44 60
cystadenocarcinoma nos 8


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Disease Ontology8 DOID:3111
NCIt39 C2971
SNOMED-CT56 21008007, 189681005
MeSH34 D003536

Related Diseases for Cystadenocarcinoma

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17GeneCards, 18GeneDecks
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Diseases related to Cystadenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 201)
idRelated DiseaseScoreTop Affiliating Genes
1mucinous cystadenocarcinoma31.5CEACAM7, MUC1, MUC16, CEACAM3
2ovarian mucinous cystadenocarcinoma31.0LMX1A, FSHR
3cystadenoma30.9FSHR, CEACAM3
4ovarian serous cystadenocarcinoma30.9ZNF217, USP2, USP14, UBE4A, MUC16
5peritonitis30.6MUC16
6pseudomyxoma peritonei30.5MUC2
7adenocarcinoma30.4CEACAM3, GAST, AKT1, MUC2, MUC16, MUC1
8sarcoma30.3MUC1, VIM
9giant cell tumor30.3CEACAM3, VIM, MUC1
10papillary carcinoma30.2MUC1, MUC16, CEACAM3, PGR, MUC2
11papillary adenocarcinoma30.1MUC2, MUC16, MUC1
12ovarian cancer30.1ESR2, PGR, AKT1, MUC16, MUC1, CEACAM3
13duodenitis29.9GAST
14ovarian cyst29.9CEACAM3, MUC16, ESR2
15colon adenocarcinoma29.9MUC2, ESR2, CEACAM7
16squamous cell carcinoma29.9MUC16, CEACAM3, CEACAM7, VIM, AKT1, MUC1
17cholangiocarcinoma29.7MUC2, CEACAM3, MUC1
18endometriosis29.7FSHR, MUC16, PGR, ESR2
19leiomyosarcoma29.7VIM, MUC16, MUC1, PGR
20rhabdomyosarcoma29.7VIM, AKT1
21pancreas disease29.7GAST
22adenosquamous carcinoma29.7MUC2, MUC1, CEACAM7, PGR
23leiomyoma29.7VIM, ESR2, PGR
24osteosarcoma29.7BIRC5, ESR2
25hepatocellular carcinoma29.7CEACAM3, CEACAM7, BIRC5, AKT1, MUC2
26endometrial carcinoma29.7ESR2, PGR, MUC16, AKT1
27pancreatic cancer29.7CEACAM3, MUC2, GAST, AKT1, BIRC5, MUC1
28adenoma29.7CEACAM3, GAST, MUC2, ESR2, MUC1, BIRC5
29colon cancer29.7CEACAM3, CEACAM7, GAST, AKT1, MUC2, ESR2
30renal clear cell carcinoma29.7BIRC5, VIM, MUC1
31papillary cystadenocarcinoma10.9
32serous cystadenocarcinoma10.8
33ovarian cystadenocarcinoma10.8
34pancreatic cystadenocarcinoma10.7
35pancreatitis10.6
36appendix mucinous cystadenocarcinoma10.5
37hepatitis10.4
38breast mucinous cystadenocarcinoma10.4
39bile duct cystadenocarcinoma10.3
40pancreatic serous cystadenocarcinoma10.3
41acinar cell cystadenocarcinoma10.3
42zollinger-ellison syndrome10.2
43cystic teratoma10.2
44mature teratoma10.2
45prostatitis10.2
46pancreatic cystadenoma10.2
47mucinous adenocarcinoma10.1
48hepatitis a10.1
49appendix adenocarcinoma10.1
50breast mucinous carcinoma10.1

Graphical network of the top 20 diseases related to Cystadenocarcinoma:



Diseases related to cystadenocarcinoma

Clinical Features for Cystadenocarcinoma

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Drugs & Therapeutics for Cystadenocarcinoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Cystadenocarcinoma

Drug clinical trials:

Search ClinicalTrials for Cystadenocarcinoma

Search NIH Clinical Center for Cystadenocarcinoma

Search CenterWatch for Cystadenocarcinoma

Genetic Tests for Cystadenocarcinoma

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Anatomical Context for Cystadenocarcinoma

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32MalaCards
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MalaCards organs/tissues related to Cystadenocarcinoma:

32
Ovary, Pancreas, Appendix, Liver, Salivary gland, Colon, Breast, Lymph node, Prostate, Testis, Lung, Spleen, Kidney, Tongue, Skin, Testes, Bone, Eye, Cervix, Endothelial, Thyroid

Animal Models for Cystadenocarcinoma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Cystadenocarcinoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537610.1FSHR, PGR, MUC2, AKT1, USP14, GAST
2MP:000200610.0ESR2, GAST, AKT1, MUC2, MUC1, PGR
3MP:00053899.9USP14, USP2, AKT1, FSHR
4MP:00053799.8GAST, USP2, AKT1, MUC2, MUC1, PGR

Publications for Cystadenocarcinoma

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50PubMed
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Articles related to Cystadenocarcinoma:

(show top 50)    (show all 594)
idTitleAuthorsYear
1
Fine-needle aspiration cytology of low-grade cribriform cystadenocarcinoma with many psammoma bodies of the salivary gland. (24255638)
2013
2
A case of mucinous cystadenocarcinoma of the pancreas with spontaneous rupture diagnosed by endoscopic retrograde pancreatography. (23526506)
2013
3
A complicated, metastatic, humeral air sac cystadenocarcinoma in a timneh African grey parrot (Psittacus erithacus timneh). (23772455)
2013
4
Synchronous papillary cystadenocarcinoma of ovary and squamous cell carcinoma of lower vagina: first report of an unusual chance occurrence. (23314878)
2013
5
Pulmonary mucinous cystadenocarcinoma: report a case and review of CT findings. (23483761)
2013
6
Serous cystadenocarcinoma of the pancreas: report of a case and management reflections. (22400805)
2012
7
Primary Mucinous Cystadenocarcinoma of the Breast: Cytologic Finding and Expression of MUC5 Are Different from Mucinous Carcinoma. (23323116)
2012
8
Primary retroperitoneal mucinous cystadenocarcinoma: a case report and review of the literature. (20558993)
2010
9
Mucinous cystadenocarcinoma of the breast with amplification of the HER2-gene confirmed by FISH: The first case reported. (20338619)
2010
10
Serous cystadenocarcinoma of the pancreas with portal thrombosis. (20499029)
2010
11
Huge liver abscess radiologically mimicking cystadenocarcinoma. (19725434)
2009
12
Mucinous Cystadenocarcinoma of the Colon during Pregnancy. (20651964)
2009
13
Cystadenocarcinoma of the appendix: an incidental perioperatory finding in a patient with adenocarcinoma of the ascending and sigmoid colon: case report and review of literature. (20387715)
2009
14
Primary retroperitoneal endometrial cystadenocarcinoma presenting as pelvic abscess on ultrasound. (18504785)
2008
15
Primary retroperitoneal mucinous cystadenocarcinoma: a case report and review of the literature. (18309690)
2007
16
Combination of tunicamycin with anticancer drugs synergistically enhances their toxicity in multidrug-resistant human ovarian cystadenocarcinoma cells. (17439664)
2007
17
Acinar cell cystadenocarcinoma of the pancreas: report of rare case and review of the literature. (15619219)
2004
18
A primary retroperitoneal serous cystadenocarcinoma with clinically aggressive behavior. (14551796)
2004
19
Primary cystadenocarcinoma of the lacrimal gland. (14522780)
2003
20
Cystadenocarcinoma of the appendix: an incidental imaging finding in a patient with adenocarcinomas of the ascending and the sigmoid colon. (14572318)
2003
21
Treatment of a case of primary retroperitoneal mucinous cystadenocarcinoma: is adjuvant hysterectomy and bilateral salpingo-oophorectomy justified? (12114915)
2002
22
DIC-CT findings of biliary cystadenocarcinoma communicating with the bile duct: a case report. (11490785)
2001
23
Complete response of a stage IV mucinous cystadenocarcinoma of the ovary to systemic chemotherapy employing paclitaxel and carboplatin. (11598367)
2001
24
Hormone replacement therapy after invasive ovarian serous cystadenocarcinoma treatment: the effect on survival. (11201519)
2001
25
Liver cystadenocarcinoma originating in cystadenoma without mesenchymal stroma. Therapeutic strategy in case of atypical radiological criteria. A case report. (11268975)
2001
26
Mucinous cystadenocarcinoma of the parotid gland: report of a case with fine needle aspiration findings and histologic correlation. (11480726)
2001
27
Mucinous appendicular cystadenocarcinoma and pregnancy. (11414527)
2001
28
Chondrosarcomatous differentiation in metastatic deposit of serous papillary cystadenocarcinoma. (10886727)
2000
29
Transplantation of a human ovarian cystadenocarcinoma into severe combined immunodeficient (SCID) mice--formation of metastases without significant alteration of the tumour cell phenotype. (8977374)
1996
30
Primitive mucinous cystadenocarcinoma of the retroperitoneum. Case report and diagnostic considerations. (8744823)
1996
31
A case of extrahepatic biliary cystadenocarcinoma arising in the hepatoduodenal ligament. (7801926)
1995
32
Needle aspiration cytology in the diagnosis of mucinous cystadenocarcinoma of pancreas. A study of five cases with an emphasis on utility and differential diagnosis. (7520925)
1994
33
An alpha-fetoprotein producing pancreatic cystadenocarcinoma. (7522067)
1994
34
Parovarian cystadenocarcinoma of low malignant potential. (1819876)
1991
35
Hyperamylasemia with papillary serous cystadenocarcinoma of the ovary. (2482644)
1989
36
A case of biliary cystadenocarcinoma with morphologic and histochemical features of hepatocytes. (2548702)
1989
37
Papillary cystadenocarcinoma of the bile ducts resulting in hemobilia. (2688401)
1989
38
Mucinous cystadenocarcinoma of the colon. Report of a case. (2920632)
1989
39
Serous cystadenocarcinoma of the pancreas: a new entity? (2909198)
1989
40
Osteosarcoma of the myometrium synchronous with bilateral papillary cystadenocarcinoma of the ovary and papillary adenocarcinoma of the cervix. (3163444)
1988
41
Ovarian mucinous cystadenocarcinoma of low malignant potential associated with a mature cystic teratoma. (3338676)
1988
42
Mucinous cystadenocarcinoma of the pancreas. Morphologic and immunocytochemical observations. (3789255)
1987
43
Hyperamylasemia with papillary serous cystadenocarcinoma of the ovary. (6206939)
1984
44
Pancreatic cystadenocarcinoma--a diagnostic problem. (6850233)
1983
45
Zollinger-Ellison syndrome due to a gastrin-producing ovarian cystadenocarcinoma. (7296246)
1981
46
Mucinous cystadenocarcinoma of the retroperitoneum. (854250)
1977
47
Hypoglycemia associated with serous cystadenocarcinoma of the ovary. (4189963)
1970
48
Argentaffin cells in mucinous cystadenocarcinoma of the ovary. (5921071)
1966
49
The incidence and appearance of roentgenologically visible psammomatous calcification of papillary cystadenocarcinoma of the ovaries. (14019282)
1962
50
The factors influencing prognosis in the treatment of papillary cystadenocarcinoma of the ovary. (13136384)
1953

Genetic Variations for Cystadenocarcinoma

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Expression for genes affiliated with Cystadenocarcinoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cystadenocarcinoma

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Pathways for genes affiliated with Cystadenocarcinoma

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37NCBI BioSystems Database, 53Reactome, 29KEGG
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Pathways related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.3ESR2, FSHR, PGR
2
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10.3MUC1, MUC16, MUC2
310.2AKT1, AMY1A, AMY1B, AMY1C
4
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10.1AMY1C, AMY1B, AMY1A, GAST

Compounds for genes affiliated with Cystadenocarcinoma

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44Novoseek, 49PharmGKB, 28IUPHAR, 11DrugBank, 59Tocris Bioscience, 24HMDB, 2BitterDB
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Compounds related to Cystadenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 69)
idCompoundScoreTop Affiliating Genes
1estrogen4410.9CEACAM7
2butyrate4410.8CEACAM7
3sialic acid4410.7CEACAM3, FSHR
4cycloheximide4410.7CEACAM7
5dexamethasone44 49 28 1113.7AKT1, MUC2, MUC16, BIRC5
6mucicarmine4410.6CEACAM3, CEACAM7, MUC1, VIM
7metronidazole44 1111.6GAST, MUC1, CEACAM3
84-hydroxytamoxifen4410.6VIM, AKT1, ESR2, PGR
9progestin4410.6ESR2, PGR, MUC1, VIM
10dtpa4410.6GAST, MUC1, CEACAM3
11hematoxylin4410.6VIM, MUC2, MUC16, MUC1, CEACAM3
12b 7234410.6MUC1, CEACAM3, CEACAM7, MUC16, VIM
13creatinine4410.6GAST, MUC16, CEACAM3
14resveratrol44 59 11 2413.6GAST, PGR
15mifepristone44 59 28 1113.6ESR2, BIRC5, MUC1, PGR
16gefitinib44 49 1112.6ESR2, CEACAM7, AKT1, VIM, BIRC5
17crcs4410.6MUC1, BIRC5, MUC2
18agar4410.5BIRC5, PGR, AKT1, VIM, MUC1
19adriamycin4410.5PGR, MUC1, CEACAM3, BIRC5, VIM, AKT1
20dmso4410.5MUC2, ESR2, BIRC5, VIM, MUC1, PGR
21thymidylate4410.5CEACAM3, ESR2, BIRC5, VIM
22methotrexate44 49 1112.5PGR, MUC1, BIRC5, CEACAM3, MUC2, VIM
23paclitaxel44 49 1112.5PGR, BIRC5, MUC16, AKT1
245fluorouracil4410.5PGR, MUC2, MUC1, CEACAM3, CEACAM7, BIRC5
25gnrh4410.5ESR2, PGR, FSHR, GAST, VIM, AKT1
26tamoxifen44 49 28 1113.5BIRC5, CEACAM3, ESR2, VIM, AKT1, MUC1
27estradiol44 11 2412.5PGR, VIM, MUC16, MUC1, BIRC5, FSHR
28actinomycin d4410.5MUC2, BIRC5, ESR2, CEACAM7, MUC1, AKT1
29dihydrotestosterone44 28 11 2413.5ESR2, VIM, MUC1, PGR
30sb 20358044 5911.5BIRC5, MUC2, GAST, VIM, AKT1
31doxorubicin44 49 1112.4MUC16, PGR, BIRC5, CEACAM3, ESR2, AKT1
32thymidine44 2411.4CEACAM3, FSHR, MUC1, GAST, CEACAM7, BIRC5
33adenylate4410.4VIM, PGR, AKT1, GAST, FSHR, ESR2
34steroid4410.4CEACAM3, FSHR, BIRC5, MUC16
35retinoic acid44 2411.4BIRC5, VIM, AKT1, MUC2, MUC1, PGR
36paraffin4410.4MUC2, MUC1, BIRC5, ESR2, AKT1, VIM
37thyroxine44 2411.3PGR, CEACAM7, CEACAM3, GAST
38testosterone44 59 11 2413.3ESR2, MUC16, MUC1, BIRC5, PGR, FSHR
39alanine4410.3FSHR, BIRC5, PGR, GAST, VIM, AKT1
40vegf4410.3MUC1, PGR, BIRC5, ESR2, CEACAM3, MUC16
415-aza-2deoxycytidine4410.3VIM, MUC2, PGR, ESR2
42cysteine4410.3FSHR, PGR, VIM, AKT1, MUC1, MUC2
43progesterone44 59 28 11 2414.3CEACAM3, VIM, MUC2, MUC16, MUC1, PGR
44genistein44 28 59 2 11 2415.3VIM, AKT1, PGR, BIRC5, ESR2
45serine4410.3BIRC5, MUC1, MUC16, MUC2, AKT1, GAST
46indium4410.2CEACAM3, MUC1
47folate4410.2PGR, MUC1, GAST, VIM
48glucose4410.2AKT1, MUC2, CEACAM3, BIRC5, MUC16, MUC1
49threonine4410.1AKT1, FSHR, MUC1, MUC16, MUC2, BIRC5
50fundal4410.0GAST, PGR

GO Terms for genes affiliated with Cystadenocarcinoma

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16Gene Ontology
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Cellular components related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:00579610.3MUC1, MUC16, MUC2

Biological processes related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1O-glycan processingGO:01626610.3MUC1, MUC16, MUC2

Molecular functions related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1enzyme bindingGO:01989910.2ESR2, BIRC5, PGR, AKT1
2protein bindingGO:0055159.1ESR2, VIM, AMY1C, UBE4A, GAST, USP14

Products for genes affiliated with Cystadenocarcinoma

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Sources for Cystadenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet