MCID: CYS014
MIFTS: 45

Cystadenocarcinoma malady

Summaries for Cystadenocarcinoma

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 An adenocarcinoma that derives from epithelial cells originating in glandular tissue, in which cystic accumulations of retained secretions are formed.

MalaCards: Cystadenocarcinoma, also known as cystadenocarcinoma nos, is related to mucinous cystadenocarcinoma and ovarian mucinous cystadenocarcinoma. An important gene associated with Cystadenocarcinoma is FSHR (follicle stimulating hormone receptor), and among its related pathways are Ovarian Infertility Genes and O-linked glycosylation of mucins. The compounds estrogen and butyrate have been mentioned in the context of this disorder. Related mouse phenotypes are homeostasis/metabolism and tumorigenesis.

Wikipedia:64 Cystadenocarcinoma is a malignant form of a cystadenoma and is a malignant neoplasm derived from... more...

Aliases & Classifications for Cystadenocarcinoma

Sources:
8Disease Ontology, 45Novoseek, 61UMLS, 40NCIt, 35MeSH, 57SNOMED-CT
See all sources

Aliases & Descriptions:

cystadenocarcinoma 8 45 61
cystadenocarcinoma nos 8


External Ids:

Disease Ontology8 DOID:3111
NCIt40 C2971
SNOMED-CT57 21008007, 189681005
MeSH35 D003536

Related Diseases for Cystadenocarcinoma

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Cystadenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 176)
idRelated DiseaseScoreTop Affiliating Genes
1mucinous cystadenocarcinoma31.6MUC16, MUC1, CEACAM7, CEACAM3
2ovarian mucinous cystadenocarcinoma31.1LMX1A, FSHR
3cystadenoma31.0FSHR, CEACAM3
4ovarian serous cystadenocarcinoma30.9UBE4A, USP14, USP2, MUC16, ZNF217
5pseudomyxoma peritonei30.6MUC2
6adenocarcinoma30.5MUC16, MUC2, AKT1, GAST, VIM, MUC1
7papillary carcinoma30.2CEACAM3, PGR, MUC1, MUC16, MUC2
8squamous cell carcinoma30.0VIM, AKT1, MUC2, MUC16, MUC1, BIRC5
9adenosquamous carcinoma29.8MUC2, MUC1, PGR, CEACAM7
10adenoma29.8GAST, MUC2, MUC1, BIRC5, FSHR, ESR2
11renal clear cell carcinoma29.8VIM, MUC1, BIRC5
12papillary cystadenocarcinoma10.9
13serous cystadenocarcinoma10.9
14appendix mucinous cystadenocarcinoma10.6
15breast mucinous cystadenocarcinoma10.4
16bile duct cystadenocarcinoma10.4
17pancreatic serous cystadenocarcinoma10.4
18acinar cell cystadenocarcinoma10.4
19malignant ovarian cyst10.3
20teratoma10.3
21zollinger-ellison syndrome10.3
22urachal cyst10.3
23parovarian cyst10.2
24mucinous adenocarcinoma10.2
25appendix adenocarcinoma10.2
26pancreatic non-invasive mucinous cystadenocarcinoma10.1
27multilocular clear cell renal cell carcinoma10.1
28ovarian cystic teratoma10.1
29ovarian clear cell cystadenocarcinoma10.1
30peritoneal carcinoma10.1
31pancreatic invasive mucinous cystadenocarcinoma10.0
32obstructive jaundice10.0
33cribriform carcinoma10.0
34ovary papillary carcinoma10.0
35peutz-jeghers syndrome10.0
36appendix cancer10.0
37peutz–jeghers syndrome10.0
38peritonitis10.0MUC16
39pericardial effusion10.0MUC16
40bladder carcinoma10.0MUC2
41ductal carcinoma in situ10.0PGR
42esophagitis10.0GAST
43stomach cancer10.0GAST
44thyroid cancer10.0AKT1
45syringoma10.0MUC1, CEACAM3
46bronchogenic cyst10.0MUC16
47gastritis10.0GAST
48sertoli-leydig cell tumor10.0PGR, MUC1
49secretory meningioma10.0VIM, MUC1
50li-fraumeni syndrome10.0PGR

Graphical network of the top 20 diseases related to Cystadenocarcinoma:



Diseases related to cystadenocarcinoma

Clinical Features for Cystadenocarcinoma

Drugs & Therapeutics for Cystadenocarcinoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Cystadenocarcinoma

Drug clinical trials:

Search ClinicalTrials for Cystadenocarcinoma

Search NIH Clinical Center for Cystadenocarcinoma

Search CenterWatch for Cystadenocarcinoma

Genetic Tests for Cystadenocarcinoma

Anatomical Context for Cystadenocarcinoma

Animal Models for Cystadenocarcinoma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Cystadenocarcinoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537610.1GAST, AKT1, MUC2, PGR, FSHR, USP14
2MP:000200610.0MUC1, PGR, FSHR, ESR2, MUC2, AKT1
3MP:00053899.9USP2, FSHR, AKT1, USP14
4MP:00053799.8ESR2, MUC2, GAST, FSHR, USP2, AKT1

Publications for Cystadenocarcinoma

Sources:
51PubMed
See all sources

Articles related to Cystadenocarcinoma:

(show top 50)    (show all 594)
idTitleAuthorsYear
1
Serous papillary cystadenocarcinoma in supernumerary ovary. (23550880)
2013
2
Cytologic features of low-grade cribriform cystadenocarcinoma of the submandibular gland: a case report. (23406647)
2013
3
Cystadenocarcinoma of the parotid: case report of a BRAF inhibitor treatment. (24386625)
2013
4
Retraction. LMX1A as a prognostic marker in ovarian mucinous cystadenocarcinoma. (22706874)
2012
5
Neoplastic transformation of endocervicosis into an extraovarian mucinous cystadenocarcinoma. (21237491)
2011
6
Imaging of pancreatic serous cystadenocarcinoma. (22009426)
2011
7
A rare renal epithelial tumor: mucinous cystadenocarcinoma case report and review of the literature. (22110514)
2011
8
Biliary cystadenocarcinoma of the gall bladder: a case report. (19946551)
2009
9
F-18 FDG PET/CT scan in biliary cystadenocarcinoma. (19542961)
2009
10
Peritoneal implantations of papillary serous ovarian cystadenocarcinoma 13 days after initial laparoscopic treatment for a presumed benign ovarian cyst. (19317271)
2009
11
Papillary cystadenocarcinoma: report of a case of high-grade histopathologic malignancy. (17045438)
2007
12
Mucinous cystadenocarcinoma of the appendix invading the ascending colon with fistula formation: report of a case. (17713739)
2007
13
Multilocular cystadenoma and cystadenocarcinoma of the prostate. (17208134)
2007
14
Cystadenocarcinoma of salivary gland presenting as a cystic lesion in the mandible. (16448922)
2006
15
Primary hepatic malignant fibrous histiocytoma mimicking cystadenocarcinoma: a case report. (17085355)
2006
16
Cystadenocarcinoma of the gallbladder. (17139440)
2006
17
Cystadenocarcinoma (papillary cystadenocarcinoma) of the submandibular gland. (16995970)
2006
18
Papillary ovarian cystadenocarcinoma in a dog. (15900901)
2005
19
Urachal mucinous cystadenocarcinoma with a cystic ovarian metastasis. (12646487)
2003
20
Multilocular cystic hepatocellular carcinoma (CHCC) mimicking mucinous cystadenocarcinoma. (12749223)
2003
21
Immunohistochemical localization of aromatase and apoptosis-associated proteins in ovarian serous cystadenocarcinoma arising from ovarian endometriosis. (11516810)
2001
22
An osteoclast-like giant cell tumor pattern in a mucinous cystadenocarcinoma of the pancreas with lymph node metastasis in a patient surviving over 10 years. (11407484)
2001
23
Borderline serous cystadenocarcinoma with coexistent angiosarcoma: an unusual form of ovarian carcinosarcoma. (12574850)
2001
24
Mucinous cystadenocarcinoma of the retroperitoneum: report of a case. (11510618)
2001
25
Oncocytic biliary cystadenocarcinoma is a form of intraductal oncocytic papillary neoplasm of the liver. (11743055)
2001
26
Ruptured retroperitoneal mucinous cystadenocarcinoma with synchronous gastric carcinoma and a long postoperative survival: case report. (10649275)
2000
27
Krukenberg tumor of ovary with features of mucinous cystadenocarcinoma. (10921229)
1999
28
Serous cystadenocarcinoma of the pancreas with liver metastases. (9931400)
1998
29
Cystadenocarcinoma of the pancreas: characteristics and surgical strategy. (9356844)
1997
30
Estrogen and progesterone receptor status as prognostic indicators in patients with optimally cytoreduced stage IIIc serous cystadenocarcinoma of the ovary. (8774651)
1996
31
Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. (7644647)
1995
32
Ovarian mucinous cystadenocarcinoma with sarcoma-like mural nodules. (7534853)
1995
33
Colonic carcinoma metastasis to ovary having serous cystadenocarcinoma -- an unusual case of double ovarian malignancy. (8932579)
1995
34
Lymphadenectomy in stage-III serous cystadenocarcinoma of the ovary. (8745090)
1995
35
Papillary cystadenocarcinoma of salivary-glands - an immunohistochemical study. (21566964)
1994
36
Stage III papillary serous cystadenocarcinoma of the ovary in a 15-year-old female. (8188094)
1994
37
Fine-needle aspiration biopsy of hepatic papillary cystadenocarcinoma in Caroli's disease. (1568414)
1992
38
A case of biliary cystadenocarcinoma arising in the liver with a congenital retention of indocyanine green. (1332426)
1992
39
Unique appearance of the duodenal papilla in pancreatic cystadenocarcinoma. (2539985)
1989
40
Cystadenocarcinoma of the pancreas 9 years after a pancreatic cyst operation: report of a case. (2703062)
1989
41
Parovarian serous cystadenocarcinoma of borderline malignancy diagnosed during pregnancy. (3240895)
1988
42
Biliary cystadenocarcinoma of extrahepatic duct origin arising in previously benign cystadenoma. (3318405)
1987
43
Cytogenetics of a cell line derived from an ovarian papillary serous cystadenocarcinoma. (6744227)
1984
44
Mucinous cystadenocarcinoma of the ovary associated with pregnancy, case report and review. (7144725)
1982
45
Metastatic, papillary cystadenocarcinoma of the mammary gland in a black-footed ferret. (7463613)
1980
46
Kinetics of growth and ectopic production of human chorionic gonadotropin by an ovarian cystadenocarcinoma cell line maintained in vitro. (626979)
1978
47
Pancreatic cystadenocarcinoma: CT body scan and gray scale ultrasound appearance. (98023)
1978
48
Mucinous cystadenoma and cystadenocarcinoma of the vermiform appendix with particular reference to mucocele and pseudomyxoma peritonei. (4718966)
1973
49
Ultrastructure of ovarian tumors. I. Papillary serous cystadenocarcinoma. (4910128)
1970
50
Disseminated endosalpingiosis associated with bilateral papillary serous cystadenocarcinoma of the ovaries. A case report. (13909448)
1962

Genetic Variations for Cystadenocarcinoma

Expression for genes affiliated with Cystadenocarcinoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cystadenocarcinoma

Search GEO for disease gene expression data for Cystadenocarcinoma.

Pathways for genes affiliated with Cystadenocarcinoma

Sources:
38NCBI BioSystems Database, 54Reactome, 30KEGG
See all sources

Pathways related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.3FSHR, PGR, ESR2
2
Hide members
10.3MUC1, MUC16, MUC2
310.2AKT1, AMY1C, AMY1B, AMY1A
4
Hide members
10.1GAST, AMY1C, AMY1B, AMY1A

Compounds for genes affiliated with Cystadenocarcinoma

Sources:
45Novoseek, 50PharmGKB, 29IUPHAR, 11DrugBank, 60Tocris Bioscience, 24HMDB, 2BitterDB
See all sources

Compounds related to Cystadenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 69)
idCompoundScoreTop Affiliating Genes
1estrogen4510.9CEACAM7
2butyrate4510.8CEACAM7
3sialic acid4510.7CEACAM3, FSHR
4cycloheximide4510.7CEACAM7
5dexamethasone45 50 29 1113.7AKT1, MUC2, MUC16, BIRC5
6mucicarmine4510.6CEACAM3, CEACAM7, MUC1, VIM
7metronidazole45 1111.6GAST, MUC1, CEACAM3
84-hydroxytamoxifen4510.6VIM, AKT1, ESR2, PGR
9progestin4510.6ESR2, PGR, MUC1, VIM
10dtpa4510.6GAST, MUC1, CEACAM3
11hematoxylin4510.6VIM, MUC2, MUC16, MUC1, CEACAM3
12b 7234510.6MUC1, CEACAM3, CEACAM7, MUC16, VIM
13creatinine4510.6GAST, MUC16, CEACAM3
14resveratrol45 60 11 2413.6GAST, PGR
15mifepristone45 60 29 1113.6ESR2, BIRC5, MUC1, PGR
16gefitinib45 50 1112.6ESR2, CEACAM7, AKT1, VIM, BIRC5
17crcs4510.6MUC1, BIRC5, MUC2
18agar4510.5BIRC5, PGR, AKT1, VIM, MUC1
19adriamycin4510.5PGR, MUC1, CEACAM3, BIRC5, VIM, AKT1
20dmso4510.5MUC2, ESR2, BIRC5, VIM, MUC1, PGR
21thymidylate4510.5CEACAM3, ESR2, BIRC5, VIM
22methotrexate45 50 1112.5PGR, MUC1, BIRC5, CEACAM3, MUC2, VIM
23paclitaxel45 50 1112.5PGR, BIRC5, MUC16, AKT1
245fluorouracil4510.5PGR, MUC2, MUC1, CEACAM3, CEACAM7, BIRC5
25gnrh4510.5ESR2, PGR, FSHR, GAST, VIM, AKT1
26tamoxifen45 50 29 1113.5BIRC5, CEACAM3, ESR2, VIM, AKT1, MUC1
27estradiol45 11 2412.5PGR, VIM, MUC16, MUC1, BIRC5, FSHR
28actinomycin d4510.5MUC2, BIRC5, ESR2, CEACAM7, MUC1, AKT1
29dihydrotestosterone45 29 11 2413.5ESR2, VIM, MUC1, PGR
30sb 20358045 6011.5BIRC5, MUC2, GAST, VIM, AKT1
31doxorubicin45 50 1112.4MUC16, PGR, BIRC5, CEACAM3, ESR2, AKT1
32thymidine45 2411.4CEACAM3, FSHR, MUC1, GAST, CEACAM7, BIRC5
33adenylate4510.4VIM, PGR, AKT1, GAST, FSHR, ESR2
34steroid4510.4CEACAM3, FSHR, BIRC5, MUC16
35retinoic acid45 2411.4BIRC5, VIM, AKT1, MUC2, MUC1, PGR
36paraffin4510.4MUC2, MUC1, BIRC5, ESR2, AKT1, VIM
37thyroxine45 2411.3PGR, CEACAM7, CEACAM3, GAST
38testosterone45 60 11 2413.3ESR2, MUC16, MUC1, BIRC5, PGR, FSHR
39alanine4510.3FSHR, BIRC5, PGR, GAST, VIM, AKT1
40vegf4510.3MUC1, PGR, BIRC5, ESR2, CEACAM3, MUC16
415-aza-2deoxycytidine4510.3VIM, MUC2, PGR, ESR2
42cysteine4510.3FSHR, PGR, VIM, AKT1, MUC1, MUC2
43progesterone45 60 29 11 2414.3CEACAM3, VIM, MUC2, MUC16, MUC1, PGR
44genistein45 29 60 2 11 2415.3VIM, AKT1, PGR, BIRC5, ESR2
45serine4510.3BIRC5, MUC1, MUC16, MUC2, AKT1, GAST
46indium4510.2CEACAM3, MUC1
47folate4510.2PGR, MUC1, GAST, VIM
48glucose4510.2AKT1, MUC2, CEACAM3, BIRC5, MUC16, MUC1
49threonine4510.1AKT1, FSHR, MUC1, MUC16, MUC2, BIRC5
50fundal4510.0GAST, PGR

GO Terms for genes affiliated with Cystadenocarcinoma

Sources:
16Gene Ontology
See all sources

Cellular components related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:00579610.3MUC1, MUC16, MUC2

Biological processes related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1O-glycan processingGO:01626610.3MUC1, MUC16, MUC2

Molecular functions related to Cystadenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1enzyme bindingGO:01989910.2ESR2, BIRC5, PGR, AKT1
2protein bindingGO:0055159.1ESR2, VIM, AMY1C, UBE4A, GAST, USP14

Products for genes affiliated with Cystadenocarcinoma

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Sources for Cystadenocarcinoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet