MCID: CYS009
MIFTS: 51

Cystadenoma malady

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Summaries for Cystadenoma

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Wikipedia:65 Cystadenoma (or \"cystoma\") refers to a type of cystic adenoma. more...

MalaCards based summary: Cystadenoma, also known as cystoma, is related to ovarian cystadenoma and ovarian serous cystadenocarcinoma. An important gene associated with Cystadenoma is CLU (clusterin), and among its related pathways are Validated targets of C-MYC transcriptional repression and ATF-2 transcription factor network. The compounds ctp and agarose have been mentioned in the context of this disorder. Affiliated tissues include pancreas, appendix and ovary, and related mouse phenotypes are other and renal/urinary system.

Disease Ontology:8 An adenoma that is a cystic.

Aliases & Classifications for Cystadenoma

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 39NCIt, 57SNOMED-CT, 34MeSH
See all sources

Cystadenoma, Aliases & Descriptions:

Name: Cystadenoma 8 10 44 62
 
Cystoma 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:2634
NCIt39 C2972
SNOMED-CT57 189680006, 47620003
MeSH34 D003537

Related Diseases for Cystadenoma

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Diseases related to Cystadenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 165)
idRelated DiseaseScoreTop Affiliating Genes
1ovarian cystadenoma31.2SELE, CLU, BRCA1
2ovarian serous cystadenocarcinoma30.3FSHR, BRAF
3adenoma30.2FSHR, BRAF, BRCA1
4leiomyomatosis30.1PGR, FH
5adenosarcoma30.1PGR, MME
6smooth muscle tumor30.0PGR, MME
7polycystic kidney disease29.9CLU, BRAF
8leiomyoma29.9PGR, MME, FH
9hypothyroidism29.8BRAF, FSHR
10cholangiocarcinoma29.6MME, BRAF
11ovarian cancer29.6CLU, BRCA1, BRAF, PGR
12adenocarcinoma29.6CLU, BRCA1, BRAF, PGR, MME, FSHR
13breast cancer29.1MME, PGR, BRAF, BRCA1, CLU
14pancreatitis10.9
15cystadenocarcinoma10.7
16pancreatic serous cystadenoma10.7
17pancreatic cystadenoma10.6
18pancreatic mucinous cystadenoma10.5
19hepatitis10.5
20leukostasis10.4SELE
21von hippel-lindau disease10.4
22prostatitis10.4
23obstructive jaundice10.4
24mucinous ovarian cystadenoma10.4
25kidney cancer10.4FH
26microcystic adenoma10.3
27hidrocystoma10.3
28familial colorectal cancer10.3FH, BRCA1
29membranous glomerulonephritis10.3MME, CLU
30bile duct cystadenoma10.3
31intussusception10.3
32pseudomyxoma peritonei10.3
33oxyphilic adenoma10.2FH, MME
34renal clear cell carcinoma10.2MME, FH
35bilateral breast cancer10.2PGR, BRCA1
36seminal vesicle cystadenoma10.2
37zollinger-ellison syndrome10.2
38extrahepatic bile duct cystadenoma10.2
39endometriosis10.2
40peritonitis10.2
41warthin tumor10.2
42teratoma10.2
43male breast cancer10.2PGR, BRCA1
44sickle cell disease10.2BRCA1, SELE
45myoma10.2FH, PGR
46malignant mixed mullerian tumor10.2MME, PGR
47breast cancer, invasive ductal10.2PGR, BRCA1
48phyllode tumor10.2PGR, MME
49ductal carcinoma in situ10.2BRCA1, PGR
50gynecomastia10.2BRCA1, PGR

Graphical network of the top 20 diseases related to Cystadenoma:



Diseases related to cystadenoma

Symptoms for Cystadenoma

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Drugs & Therapeutics for Cystadenoma

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Drug clinical trials:

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Search NIH Clinical Center for Cystadenoma

Genetic Tests for Cystadenoma

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Anatomical Context for Cystadenoma

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MalaCards organs/tissues related to Cystadenoma:

32
Pancreas, Appendix, Ovary, Liver, Prostate, Colon, Testis, Kidney, Lung, Salivary gland, Spleen, Thyroid, Breast, Smooth muscle, Bone, Endothelial, Tongue, Pituitary

Animal Models for Cystadenoma or affiliated genes

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MGI Mouse Phenotypes related to Cystadenoma:

36 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053959.3CLU, MME, FSHR
2MP:00053678.7FH, BRAF, BRCA1, CLU
3MP:00053698.4PGR, BRAF, BRCA1, CLU
4MP:00020068.3FSHR, PGR, BRAF, BRCA1
5MP:00053977.6SELE, BRCA1, BRAF, PGR, FSHR
6MP:00053857.6SELE, CLU, BRCA1, BRAF, PGR, FSHR
7MP:00107717.5SELE, BRCA1, BRAF, PGR, MME, FSHR
8MP:00053847.5SELE, BRCA1, BRAF, PGR, FSHR, FH
9MP:00053867.4SELE, BRCA1, BRAF, PGR, FSHR
10MP:00107687.3SELE, BRCA1, BRAF, PGR, FSHR, FH
11MP:00053877.2SELE, CLU, BRCA1, BRAF, PGR, MME
12MP:00053766.9FH, SELE, CLU, BRCA1, BRAF, PGR

Publications for Cystadenoma

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Articles related to Cystadenoma:

(show top 50)    (show all 656)
idTitleAuthorsYear
1
MRI in differentiating ovarian borderline from benign mucinous cystadenoma: Pathological correlation. (24123278)
2014
2
Multiple bilateral nonpapillary serous cystadenoma of the epididymis. (23987181)
2013
3
Hepatobiliary cystadenoma: a rare pediatric tumor. (23483342)
2013
4
Pancreas serous cystadenoma: typical imaging aspect of a rare tumor. (23847830)
2013
5
Rate of growth of pancreatic serous cystadenoma as an indication for resection. (24074417)
2013
6
Re: coexistence of struma ovarii and serous cystadenoma of the ovary. (23202789)
2013
7
An unexpected finding of a rare intrascrotal lesion: the sertoliform cystadenoma of the rete testis. (23429025)
2013
8
Congenital biliary tract malformation resembling biliary cystadenoma in a captive juvenile African lion (Panthera leo). (23272363)
2012
9
Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells. (21792894)
2012
10
Differentiating pancreatic ductal adenocarcinoma from pancreatic serous cystadenoma, mucinous cystadenoma, and a pseudocyst with detailed analysis of cystic features on CT scans: a preliminary study. (21430935)
2011
11
Giant mucinous cystadenoma: case report. (20499763)
2010
12
Papillary cystadenoma of the epididymis. (20367315)
2010
13
A rare case of primary mucinous cystadenoma of spleen. (22461876)
2009
14
Diffuse pancreatic serous cystadenoma associated with neuroendocrine carcinoma: a case report and review of literature. (19129617)
2009
15
Predictive value of multi-detector computed tomography for accurate diagnosis of serous cystadenoma: radiologic-pathologic correlation. (19522024)
2009
16
Clinical challenges and images in GI. Extrahepatic biliary cystadenoma with mesenchymal stroma. (18471506)
2008
17
Massive mucinous cystadenoma of the appendix with intussusception in an adult: usefulness of reconstructed computed tomography images. (18301985)
2008
18
Cystadenoma of the palate: immunohistochemistry of mucins. (18705774)
2008
19
Large multilocular serous cystadenoma of the pancreatic head. (18457108)
2008
20
Biliary cystadenoma of the left intrahepatic duct (2007: 2b). (17356842)
2007
21
Papillary cystadenoma of the nasal cavity. (17967660)
2007
22
Serous cystadenoma of the epididymis of common epithelial ovarian type: case report with an immunohistochemical study. (17318978)
2006
23
Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma. (17007033)
2006
24
Successful cystic fenestration for a macrocystic serous cystadenoma of the pancreas causing obstructive jaundice: report of a case. (16378203)
2006
25
Clinical significance of N-acetyl-L-aspartate resonance in ovarian mucinous cystadenoma. (16445669)
2006
26
Unusual imaging appearances of pancreatic serous cystadenoma: correlation with surgery and pathologic analysis. (15759200)
2005
27
Mixed serous cystadenoma with mucinous cystadenoma of the pancreas. (15968256)
2005
28
Young woman with jaundice and itching. Bilary cystadenoma. (15887662)
2005
29
Mucinous cystadenoma of the pancreas with predominant stroma creating a solid tumor. (16146567)
2005
30
Contrast-enhanced ultrasonography in the characterization of pancreatic mucinous cystadenoma. (15284474)
2004
31
Mucinous cystadenoma of the pancreas in a one-year-old child. (15486909)
2004
32
Molecular genetic analysis of ovarian serous cystadenomas. (15077125)
2004
33
Sarcoma-like mural nodule in an ovarian mucinous cystadenoma: a case report. (16295477)
2004
34
Mucinous cystadenoma of the testis. (15201756)
2004
35
Ovarian mucinous cystadenoma in a female with Turner syndrome. (15448783)
2004
36
Ovarian yolk sac tumor associated with endometrioid carcinoma and mucinous cystadenoma of the ovary. (14571433)
2003
37
Mature cystic teratoma of the ovary associated with complete colonic wall and mucinous cystadenoma. (14584762)
2003
38
Serous microcystic adenoma (glycogen-rich cystadenoma) of the pancreas: study of 11 cases showing clinicopathological and immunohistochemical correlations. (12031087)
2002
39
Immunohistochemical analysis of cytokeratin expression in apocrine cystadenoma or hidrocystoma. (10472758)
1999
40
Periampullary carcinoma with bilateral ovarian cystadenoma in pregnancy. (9563228)
1998
41
Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. (7644647)
1995
42
Clinicostatistical study of low potential malignancy ovarian cystadenoma (borderline cases). (1867577)
1991
43
Neonatal cytomegalovirus infection with pancreatic cystadenoma and nephrotic syndrome. (3035523)
1986
44
Zollinger-Ellison syndrome due to a gastrin secreting ovarian mucinous cystadenoma. Case report. (4027214)
1985
45
Cystadenoma of the epididymis associated with hydrocele. (7148594)
1982
46
Conservative management of the Zollinger-Ellison syndrome. Ectopic gastrin production by an ovarian cystadenoma. (7365959)
1980
47
Sertoli-Leydig cell tumor of the ovary, with an associated mucinous cystadenoma. An ultrastructural and endocrine study. (4280005)
1974
48
A retroperitoneal mesonephric cystadenoma with features of the adenomatoid tumor of the genital tract. (4713358)
1973
49
Chromosomal aberrations in an ovarian cystadenoma. (4185609)
1969
50
Pancreatic cystadenoma in childhood. Report of a case. (5803827)
1969

Variations for Cystadenoma

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Expression for genes affiliated with Cystadenoma

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Expression patterns in normal tissues for genes affiliated with Cystadenoma

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Pathways for genes affiliated with Cystadenoma

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Pathways related to Cystadenoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8BRCA1, CLU
29.7BRCA1, SELE
3
Show member pathways
Development VEGF signaling via VEGFR2 generic cascades60
9.7SELE, BRCA1
49.3FSHR, PGR
59.3FH, BRAF

Compounds for genes affiliated with Cystadenoma

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Compounds related to Cystadenoma according to GeneCards/GeneDecks:

(show top 50)    (show all 66)
idCompoundScoreTop Affiliating Genes
1ctp449.9FSHR, CLU
2agarose449.6FSHR, BRCA1, CLU
34-hydroxytamoxifen449.6CLU, BRCA1, PGR
4tibolone449.6PGR, SELE
53beta-hydroxysteroid449.5PGR, CLU
6docetaxel44 50 61 1112.5CLU, BRCA1, PGR
7sialic acid449.5SELE, CLU, FSHR
85-aza-2deoxycytidine449.5PGR, BRCA1, CLU
9etoposide44 50 61 1112.5SELE, CLU, BRCA1
10polyacrylamide449.5BRCA1, FSHR, FH
11adriamycin449.5MME, PGR, BRCA1
12guanine44 24 1111.4FSHR, BRCA1, SELE
13cyclophosphamide44 50 1111.4SELE, BRCA1, PGR
14methotrexate50 44 1111.3SELE, BRCA1, PGR
15crcs449.3BRAF, MME
165fluorouracil449.3PGR, BRCA1, SELE
17fluticasone propionate44 50 61 1112.3SELE, PGR
18lactate449.3FH, MME, CLU, SELE
19vitamin a44 24 1111.3SELE, PGR, MME
20thymidine44 2410.3CLU, BRCA1, MME, FSHR
21folate449.2PGR, BRCA1, CLU, SELE
22tamoxifen44 50 28 1112.1SELE, CLU, BRCA1, PGR
23oxygen44 2410.1FH, MME, BRCA1, CLU
24estradiol44 24 1111.1FSHR, PGR, BRCA1, CLU
25gnrh449.0FSHR, MME, PGR, CLU
26ribonucleic acid449.0CLU, PGR, MME, FSHR
27actinomycin d449.0MME, CLU, SELE
28agar448.9BRCA1, BRAF, PGR
29matrigel448.9MME, BRAF, CLU, SELE
30adenylate448.8SELE, PGR, MME, FSHR
31oligonucleotide448.8CLU, BRCA1, BRAF, FSHR
32paclitaxel44 50 1110.8PGR, BRAF, BRCA1, CLU
33doxorubicin44 50 1110.8SELE, CLU, BRCA1, PGR, MME
34cycloheximide448.8SELE, CLU, BRCA1, PGR, MME
35steroid448.7CLU, BRCA1, PGR, MME, FSHR
36fatty acid448.6CLU, BRCA1, BRAF, MME, FH
37cysteine448.6CLU, BRCA1, PGR, MME, FSHR
38atp44 289.6FH, BRAF, BRCA1, CLU
39phosphatidylinositol448.6BRCA1, BRAF, MME, FSHR
40aspartate448.6SELE, BRAF, PGR, FH
41paraffin448.4CLU, BRCA1, BRAF, PGR, MME
42retinoic acid44 249.3CLU, BRCA1, BRAF, PGR, MME
43testosterone44 61 24 1111.2SELE, CLU, BRCA1, PGR, MME, FSHR
44alanine448.1SELE, BRCA1, BRAF, PGR, FSHR
45tyrosine448.1FH, FSHR, MME, BRAF, BRCA1, CLU
46lipid448.0SELE, CLU, BRCA1, BRAF, MME, FSHR
47serine448.0SELE, CLU, BRCA1, BRAF, MME, FSHR
48vegf447.9SELE, CLU, BRCA1, BRAF, PGR, MME
49progesterone44 28 61 24 1111.9FSHR, MME, PGR, BRAF, BRCA1, CLU
50estrogen447.9CLU, BRCA1, BRAF, PGR, MME, FSHR

GO Terms for genes affiliated with Cystadenoma

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Molecular functions related to Cystadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.0FSHR, MME, PGR, BRAF, BRCA1, CLU

Products for genes affiliated with Cystadenoma

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Sources for Cystadenoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet