MCID: CYS009
MIFTS: 50

Cystadenoma malady

Cancer diseases category
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Summaries for Cystadenoma

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8Disease Ontology, 65Wikipedia, 33MalaCards
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Wikipedia:65 Cystadenoma (or \"cystoma\") refers to a type of cystic adenoma. more...

MalaCards: Cystadenoma, also known as cystoma, is related to ovarian cystadenoma and adenoma. An important gene associated with Cystadenoma is CLU (clusterin), and among its related pathways are Validated targets of C-MYC transcriptional repression and Development VEGF signaling and activation. The compounds ctp and agarose have been mentioned in the context of this disorder. Affiliated tissues include pancreas, appendix and ovary, and related mouse phenotypes are other and renal/urinary system.

Disease Ontology:8 An adenoma that is a cystic.

Aliases & Classifications for Cystadenoma

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8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 40NCIt, 58SNOMED-CT, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

cystadenoma 8 10 45 62
cystoma 8


External Ids:

Disease Ontology8 DOID:2634
NCIt40 C2972
SNOMED-CT58 189680006, 47620003
MeSH35 D003537

Related Diseases for Cystadenoma

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17GeneCards, 18GeneDecks
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Diseases related to Cystadenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 161)
idRelated DiseaseScoreTop Affiliating Genes
1ovarian cystadenoma31.0SELE, CLU, BRCA1
2adenoma30.5BRCA1, FSHR, BRAF
3adenocarcinoma30.4PGR, MME, BRCA1, CLU, BRAF, FSHR
4ovarian cancer29.9BRCA1, CLU, BRAF, PGR
5leiomyomatosis29.9PGR, FH
6adenosarcoma29.9MME, PGR
7smooth muscle tumor29.8MME, PGR
8polycystic kidney disease29.8BRAF, CLU
9leiomyoma29.8FH, MME, PGR
10hypothyroidism29.8BRAF, FSHR
11cholangiocarcinoma29.7MME, BRAF
12colon cancer29.7CLU, BRAF, BRCA1, SELE
13breast cancer29.6BRAF, MME, BRCA1, CLU, PGR
14pancreatitis10.8
15cystadenocarcinoma10.7
16pancreatic serous cystadenoma10.6
17pancreatic cystadenoma10.6
18pancreatic mucinous cystadenoma10.5
19hepatitis10.4
20prostatitis10.4
21von hippel-lindau disease10.3
22microcystic adenoma10.3
23obstructive jaundice10.3
24mucinous ovarian cystadenoma10.3
25hidrocystoma10.3
26intussusception10.2
27pseudomyxoma peritonei10.2
28bile duct cystadenoma10.2
29seminal vesicle cystadenoma10.2
30zollinger-ellison syndrome10.2
31endometriosis10.2
32peritonitis10.2
33extrahepatic bile duct cystadenoma10.2
34intrahepatic bile duct cystadenoma10.2
35ovarian papillary cystadenoma10.2
36struma ovarii10.2
37warthin tumor10.2
38teratoma10.2
39epididymitis10.2
40leukostasis10.1SELE
41ovarian endometrioid cystadenoma10.1
42sertoli-leydig cell tumor10.1
43pancreatic colloid cystadenoma10.1
44mucinous cystadenocarcinoma10.1
45rete ovarii cystadenoma10.1
46uterine ligament papillary cystadenoma10.1
47compartment syndrome10.1
48cystic teratoma10.1
49leydig cell tumor10.1
50pancreatic ductal adenocarcinoma10.1

Graphical network of the top 20 diseases related to Cystadenoma:



Diseases related to cystadenoma

Symptoms for Cystadenoma

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Drugs & Therapeutics for Cystadenoma

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Cystadenoma

Search NIH Clinical Center for Cystadenoma

Genetic Tests for Cystadenoma

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Anatomical Context for Cystadenoma

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33MalaCards
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MalaCards organs/tissues related to Cystadenoma:

33
Pancreas, Appendix, Ovary, Liver, Prostate, Colon, Testis, Kidney, Lung, Salivary gland, Breast, Thyroid, Spleen, Smooth muscle, Endothelial, Bone, Pituitary

Animal Models for Cystadenoma or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Cystadenoma:

37 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053959.3CLU, MME, FSHR
2MP:00053678.7FH, BRAF, BRCA1, CLU
3MP:00053698.4PGR, BRAF, BRCA1, CLU
4MP:00020068.3FSHR, PGR, BRAF, BRCA1
5MP:00053977.6SELE, BRCA1, BRAF, PGR, FSHR
6MP:00053857.6SELE, CLU, BRCA1, BRAF, PGR, FSHR
7MP:00107717.5SELE, BRCA1, BRAF, PGR, MME, FSHR
8MP:00053847.5SELE, BRCA1, BRAF, PGR, FSHR, FH
9MP:00053867.4SELE, BRCA1, BRAF, PGR, FSHR
10MP:00107687.3SELE, BRCA1, BRAF, PGR, FSHR, FH
11MP:00053877.2SELE, CLU, BRCA1, BRAF, PGR, MME
12MP:00053766.9FH, SELE, CLU, BRCA1, BRAF, PGR

Publications for Cystadenoma

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52PubMed
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Articles related to Cystadenoma:

(show top 50)    (show all 626)
idTitleAuthorsYear
1
MRI in differentiating ovarian borderline from benign mucinous cystadenoma: Pathological correlation. (24123278)
2014
2
Hepatobiliary cystadenoma: a rare pediatric tumor. (23483342)
2013
3
Pancreas serous cystadenoma: typical imaging aspect of a rare tumor. (23847830)
2013
4
Rate of growth of pancreatic serous cystadenoma as an indication for resection. (24074417)
2013
5
Re: coexistence of struma ovarii and serous cystadenoma of the ovary. (23202789)
2013
6
An unexpected finding of a rare intrascrotal lesion: the sertoliform cystadenoma of the rete testis. (23429025)
2013
7
Congenital biliary tract malformation resembling biliary cystadenoma in a captive juvenile African lion (Panthera leo). (23272363)
2012
8
Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells. (21792894)
2012
9
Differentiating pancreatic ductal adenocarcinoma from pancreatic serous cystadenoma, mucinous cystadenoma, and a pseudocyst with detailed analysis of cystic features on CT scans: a preliminary study. (21430935)
2011
10
Voluminous pancreatic mucinous cystadenoma in a non-pregnant woman with rheumatoid arthritis. (22737534)
2011
11
Giant mucinous cystadenoma: case report. (20499763)
2010
12
A rare case of primary mucinous cystadenoma of spleen. (22461876)
2009
13
Diffuse pancreatic serous cystadenoma associated with neuroendocrine carcinoma: a case report and review of literature. (19129617)
2009
14
Predictive value of multi-detector computed tomography for accurate diagnosis of serous cystadenoma: radiologic-pathologic correlation. (19522024)
2009
15
Clinical challenges and images in GI. Extrahepatic biliary cystadenoma with mesenchymal stroma. (18471506)
2008
16
Massive mucinous cystadenoma of the appendix with intussusception in an adult: usefulness of reconstructed computed tomography images. (18301985)
2008
17
Cystadenoma of the palate: immunohistochemistry of mucins. (18705774)
2008
18
Large multilocular serous cystadenoma of the pancreatic head. (18457108)
2008
19
Biliary cystadenoma of the left intrahepatic duct (2007: 2b). (17356842)
2007
20
Papillary cystadenoma of the nasal cavity. (17967660)
2007
21
Serous cystadenoma of the epididymis of common epithelial ovarian type: case report with an immunohistochemical study. (17318978)
2006
22
Obstructive jaundice due to hepatobiliary cystadenoma or cystadenocarcinoma. (17007033)
2006
23
Successful cystic fenestration for a macrocystic serous cystadenoma of the pancreas causing obstructive jaundice: report of a case. (16378203)
2006
24
Clinical significance of N-acetyl-L-aspartate resonance in ovarian mucinous cystadenoma. (16445669)
2006
25
Unusual imaging appearances of pancreatic serous cystadenoma: correlation with surgery and pathologic analysis. (15759200)
2005
26
Mixed serous cystadenoma with mucinous cystadenoma of the pancreas. (15968256)
2005
27
Young woman with jaundice and itching. Bilary cystadenoma. (15887662)
2005
28
Mucinous cystadenoma of the pancreas with predominant stroma creating a solid tumor. (16146567)
2005
29
Contrast-enhanced ultrasonography in the characterization of pancreatic mucinous cystadenoma. (15284474)
2004
30
Mucinous cystadenoma of the pancreas in a one-year-old child. (15486909)
2004
31
Molecular genetic analysis of ovarian serous cystadenomas. (15077125)
2004
32
Sarcoma-like mural nodule in an ovarian mucinous cystadenoma: a case report. (16295477)
2004
33
Mucinous cystadenoma of the testis. (15201756)
2004
34
Ovarian mucinous cystadenoma in a female with Turner syndrome. (15448783)
2004
35
Simultaneous serous cystadenoma of the pancreas and mucinous cystadenoma of the appendix. (15007191)
2004
36
Ovarian yolk sac tumor associated with endometrioid carcinoma and mucinous cystadenoma of the ovary. (14571433)
2003
37
Mature cystic teratoma of the ovary associated with complete colonic wall and mucinous cystadenoma. (14584762)
2003
38
Serous microcystic adenoma (glycogen-rich cystadenoma) of the pancreas: study of 11 cases showing clinicopathological and immunohistochemical correlations. (12031087)
2002
39
Immunohistochemical analysis of cytokeratin expression in apocrine cystadenoma or hidrocystoma. (10472758)
1999
40
Periampullary carcinoma with bilateral ovarian cystadenoma in pregnancy. (9563228)
1998
41
Biliary cystadenoma and cystadenocarcinoma: clinical-imaging-pathologic correlations with emphasis on the importance of ovarian stroma. (7644647)
1995
42
Clinicostatistical study of low potential malignancy ovarian cystadenoma (borderline cases). (1867577)
1991
43
Neonatal cytomegalovirus infection with pancreatic cystadenoma and nephrotic syndrome. (3035523)
1986
44
Zollinger-Ellison syndrome due to a gastrin secreting ovarian mucinous cystadenoma. Case report. (4027214)
1985
45
Cystadenoma of the epididymis associated with hydrocele. (7148594)
1982
46
Conservative management of the Zollinger-Ellison syndrome. Ectopic gastrin production by an ovarian cystadenoma. (7365959)
1980
47
Sertoli-Leydig cell tumor of the ovary, with an associated mucinous cystadenoma. An ultrastructural and endocrine study. (4280005)
1974
48
A retroperitoneal mesonephric cystadenoma with features of the adenomatoid tumor of the genital tract. (4713358)
1973
49
Chromosomal aberrations in an ovarian cystadenoma. (4185609)
1969
50
Pancreatic cystadenoma in childhood. Report of a case. (5803827)
1969

Variations for Cystadenoma

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Expression for genes affiliated with Cystadenoma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cystadenoma

Search GEO for disease gene expression data for Cystadenoma.

Pathways for genes affiliated with Cystadenoma

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50PathCards, 38NCBI BioSystems Database, 60Thomson Reuters, 30KEGG
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Pathways related to Cystadenoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8BRCA1, CLU
2
Show member pathways
Development VEGF signaling via VEGFR2 generic cascades60
9.7BRCA1, SELE
39.7SELE, BRCA1
49.3FSHR, PGR
59.3FH, BRAF

Compounds for genes affiliated with Cystadenoma

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45Novoseek, 51PharmGKB, 61Tocris Bioscience, 11DrugBank, 24HMDB, 29IUPHAR
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Compounds related to Cystadenoma according to GeneCards/GeneDecks:

(show top 50)    (show all 66)
idCompoundScoreTop Affiliating Genes
1ctp459.9FSHR, CLU
2agarose459.6FSHR, BRCA1, CLU
34-hydroxytamoxifen459.6CLU, BRCA1, PGR
4tibolone459.6PGR, SELE
53beta-hydroxysteroid459.5PGR, CLU
6docetaxel45 51 61 1112.5CLU, BRCA1, PGR
7sialic acid459.5SELE, CLU, FSHR
85-aza-2deoxycytidine459.5PGR, BRCA1, CLU
9etoposide45 51 61 1112.5SELE, CLU, BRCA1
10polyacrylamide459.5BRCA1, FSHR, FH
11adriamycin459.5MME, PGR, BRCA1
12guanine45 24 1111.4FSHR, BRCA1, SELE
13cyclophosphamide45 51 1111.4SELE, BRCA1, PGR
14methotrexate51 45 1111.3SELE, BRCA1, PGR
15crcs459.3BRAF, MME
165fluorouracil459.3PGR, BRCA1, SELE
17fluticasone propionate45 51 61 1112.3SELE, PGR
18lactate459.3FH, MME, CLU, SELE
19vitamin a45 24 1111.3SELE, PGR, MME
20thymidine45 2410.3CLU, BRCA1, MME, FSHR
21folate459.2PGR, BRCA1, CLU, SELE
22tamoxifen45 51 29 1112.1SELE, CLU, BRCA1, PGR
23oxygen45 2410.1FH, MME, BRCA1, CLU
24estradiol45 24 1111.1FSHR, PGR, BRCA1, CLU
25gnrh459.0FSHR, MME, PGR, CLU
26ribonucleic acid459.0CLU, PGR, MME, FSHR
27actinomycin d459.0MME, CLU, SELE
28agar458.9BRCA1, BRAF, PGR
29matrigel458.9MME, BRAF, CLU, SELE
30adenylate458.8SELE, PGR, MME, FSHR
31oligonucleotide458.8CLU, BRCA1, BRAF, FSHR
32paclitaxel45 51 1110.8PGR, BRAF, BRCA1, CLU
33doxorubicin45 51 1110.8SELE, CLU, BRCA1, PGR, MME
34cycloheximide458.8SELE, CLU, BRCA1, PGR, MME
35steroid458.7CLU, BRCA1, PGR, MME, FSHR
36fatty acid458.6CLU, BRCA1, BRAF, MME, FH
37cysteine458.6CLU, BRCA1, PGR, MME, FSHR
38atp45 299.6FH, BRAF, BRCA1, CLU
39phosphatidylinositol458.6BRCA1, BRAF, MME, FSHR
40aspartate458.6SELE, BRAF, PGR, FH
41paraffin458.4CLU, BRCA1, BRAF, PGR, MME
42retinoic acid45 249.3CLU, BRCA1, BRAF, PGR, MME
43testosterone45 61 24 1111.2SELE, CLU, BRCA1, PGR, MME, FSHR
44alanine458.1SELE, BRCA1, BRAF, PGR, FSHR
45tyrosine458.1FH, FSHR, MME, BRAF, BRCA1, CLU
46lipid458.0SELE, CLU, BRCA1, BRAF, MME, FSHR
47serine458.0SELE, CLU, BRCA1, BRAF, MME, FSHR
48vegf457.9SELE, CLU, BRCA1, BRAF, PGR, MME
49progesterone45 29 61 24 1111.9FSHR, MME, PGR, BRAF, BRCA1, CLU
50estrogen457.9CLU, BRCA1, BRAF, PGR, MME, FSHR

GO Terms for genes affiliated with Cystadenoma

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16Gene Ontology
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Molecular functions related to Cystadenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.0FSHR, MME, PGR, BRAF, BRCA1, CLU

Products for genes affiliated with Cystadenoma

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Sources for Cystadenoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet