MCID: CYS008
MIFTS: 64

Cystic Echinococcosis malady

Infectious diseases, Rare diseases, Respiratory diseases, Liver diseases categories

Summaries for Cystic Echinococcosis

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9Disease Ontology, 34MalaCards
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Disease Ontology:9 An echinococcosis that is caused by the larvae of echinococcus granulosus. hepatic involvement can result in abdominal pain, a mass in the hepatic area, and biliary duct obstruction. pulmonary involvement can produce chest pain, cough, and hemoptysis. rupture of the cysts produce fever, urticaria, eosinophilia, and anaphylactic shock, as well as cyst dissemination. brain, bone, heart can also be infected.

MalaCards: Cystic Echinococcosis, also known as echinococcus granulosus infection, is related to echinococcosis and aspergillosis. An important gene associated with Cystic Echinococcosis is MT-ATP6 (mitochondrially encoded ATP synthase 6), and among its related pathways are TRAF Pathway and Immune response IL 12 signaling pathway. The compounds solium and glucuronoxylomannan have been mentioned in the context of this disorder. Affiliated tissues include thyroid, liver and lung, and related mouse phenotypes are tumorigenesis and skeleton.

Aliases & Classifications for Cystic Echinococcosis

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Sources:
9Disease Ontology, 50Orphanet, 63UMLS, 59SNOMED-CT, 28ICD9CM, 37MESH via Orphanet, 60SNOMED-CT via Orphanet, 64UMLS via Orphanet, 27ICD10 via Orphanet, 26ICD10
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Classifications:



Characteristics (Orphanet epidemiological data):

50
cystic echinococcosis:
Inheritance: Sporadic; Age of onset: Adulthood


Aliases & Descriptions:

cystic echinococcosis 9 50
echinococcus granulosus infection 9 63
echinococcus granulosus infectious disease of thyroid 9
echinococcus granulosus infectious disease of liver 9
echinococcus granulosus infection, unspecified 9
echinococcus granulosus infection of thyroid 9
echinococcus granulosus infectious disease 9
echinococcus granulosus infection of lung 9
unspecified echinococcus granulosus 9
thyroid echinococcus granulosus 9
liver echinococcus granulosus 9
lung echinococcus granulosus 9
unilocular hydatid disease 9
unilocular echinococcosis 9
hydatid disease 50
hydatidosis 50


External Ids:

Disease Ontology9 DOID:1495
ICD9CM28 122.4
MESH via Orphanet37 D004443
SNOMED-CT via Orphanet60 74942003
SNOMED-CT59 187138004, 75006000
UMLS via Orphanet64 C0013502
ICD10 via Orphanet27 B67.0, B67.1, B67.2 B67.3, B67.4, B67.5, B67.6, B67.7, B67.8, B67.9, more

Related Diseases for Cystic Echinococcosis

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Cystic Echinococcosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 150)
idRelated DiseaseScoreTop Affiliating Genes
1echinococcosis32.3MT-CO1
2aspergillosis30.2TLR2, TLR4
3helminthiasis30.1IGHE, RNASE3
4toxocariasis30.1IGHE, RNASE3
5invasive aspergillosis30.0TLR2, TLR4
6sepsis30.0TLR2, TLR4, IL17A, IL10, IL12B, IL6
7eosinophilia29.9IL10, IL2RA, RNASE3, IGHE
8hepatitis10.7
9alveolar echinococcosis10.4
10cysticercosis10.3
11trichinosis10.2
12ankylosing spondylitis10.1HLA-B
13cerebritis10.1
14peritonitis10.1
15thyroiditis10.1
16acute generalized exanthematous pustulosis10.1
17celiac disease10.1HLA-DQB1
18farmer's lung10.1IL2RA
19mitochondrial disorders10.1MT-CO1, MT-ATP6
20horner's syndrome10.1
21polycystic echinococcosis10.1
22sarcoma10.1
23leber hereditary optic neuropathy10.1MT-ATP6
24atopic dermatitis10.1RNASE3, TLR2
25paragonimiasis10.1IGHE
26colorectal cancer10.1TAP2, TAP1
27reactive arthritis10.1HLA-B, TAP2
28leprosy10.1TLR2, HLA-DRB1
29pouchitis10.1TLR2, TLR4
30melioidosis10.1TLR2, TLR4
31multiple sclerosis 110.1HLA-DQB1, HLA-DRB1
32anisakiasis10.1IGHE, RNASE3
33autoimmune thyroiditis10.1HLA-B, IL2RA, IL12B
34neisseria meningitidis infection10.1TLR2, TLR4
35intrinsic asthma10.1IGHE, RNASE3
36allergic conjunctivitis10.1IGHE, RNASE3
37kimura disease10.1IGHE, RNASE3
38eosinophilic pneumonia10.1IGHE, RNASE3
39vogt-koyanagi-harada disease10.1HLA-DRB1, IL2RA
40asthma10.1IGHE, RNASE3
41pulmonary eosinophilia10.1IGHE, RNASE3
42conjunctivitis10.0IGHE, RNASE3
43sjogren's syndrome10.0IL2RA, TAP1, TAP2
44allergic rhinitis10.0RNASE3, IGHE
45herpes simplex10.0HLA-B, TLR2, EEF1D, IL12B
46food allergy10.0IGHE, RNASE3
47meningitis10.0IL6, TLR2, HLA-B
48immunoglobulin alpha deficiency10.0HLA-DQB1, IGHE
49vernal keratoconjunctivitis10.0IGHE, RNASE3
50keratitis10.0IL17A, TLR4, TLR2

Graphical network of the top 20 diseases related to Cystic Echinococcosis:



Diseases related to cystic echinococcosis

Symptoms for Cystic Echinococcosis

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Drugs & Therapeutics for Cystic Echinococcosis

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Cystic Echinococcosis

Drug clinical trials:

Search ClinicalTrials for Cystic Echinococcosis

Search NIH Clinical Center for Cystic Echinococcosis

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Genetic Tests for Cystic Echinococcosis

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Anatomical Context for Cystic Echinococcosis

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34MalaCards
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MalaCards organs/tissues related to Cystic Echinococcosis:

34
Thyroid, Liver, Lung, Heart, Brain, Bone, Testes, Spleen, Skin, Tongue, T cells

Animal Models for Cystic Echinococcosis or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Cystic Echinococcosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.1TLR2, TLR4, IL10, IL12B, IL6, TAP1
2MP:00053908.1IL6, IL12B, IL10, IL17A, TLR4, TLR2
3MP:00053887.8HLA-DQB1, TLR2, TLR4, IL17A, IL10, IL12B
4MP:00053697.7HLA-DQB1, TLR2, TLR4, MT-CO1, IL10, IL6
5MP:00053817.5HLA-DQB1, TLR2, TLR4, IL2RA, IL17A, IL10
6MP:00053766.9IGHE, HLA-DQB1, TLR2, TLR4, MT-CO1, IL17A
7MP:00107686.8HLA-B, HLA-DQB1, TLR2, TLR4, IL2RA, IL17A
8MP:00053976.2TLR4, TLR2, HLA-DQB1, HLA-B, IGHE, IL2RA
9MP:00053876.0TAP2, IGHE, HLA-B, HLA-DQB1, TLR2, TLR4

Publications for Cystic Echinococcosis

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53PubMed
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Articles related to Cystic Echinococcosis:

(show top 50)    (show all 381)
idTitleAuthorsYear
1
Detection of hydatid-specific antibodies in the serum and urine for the diagnosis of cystic echinococcosis in patients from the Kashmir Valley, India. (24429044)
2014
2
Humoral Immune Response and Pathological Analysis in Patients with False Immune Diagnosis of Cystic Echinococcosis. (24372157)
2013
3
A review of the global prevalence, molecular epidemiology and economics of cystic echinococcosis in production animals. (23084536)
2013
4
Human cystic echinococcosis in west azerbaijan, northwest iran: a retrospective hospital based survey from 2000 to 2009. (23914247)
2013
5
High resolution melting technique for molecular epidemiological studies of cystic echinococcosis: differentiating G1, G3, and G6 genotypes of Echinococcus granulosus sensu lato. (23832641)
2013
6
Molecular diagnosis of cystic echinococcosis in humans from central Poland. (23535071)
2013
7
A systematic review of the literature on cystic echinococcosis frequency worldwide and its associated clinical manifestations. (23546806)
2013
8
Host-parasite relationship in cystic echinococcosis: an evolving story. (22110535)
2012
9
Cystic echinococcosis in sheep in Sardinia. Changing pattern and present status. (22178675)
2012
10
Development and evaluation of flow through technique for diagnosis of cystic echinococcosis in sheep. (21507576)
2011
11
Community survey, treatment and long-term follow-up for human cystic echinococcosis in northwest China. (22040575)
2011
12
TLR2 and TLR4 expression in peripheral blood mononuclear cells of patients with chronic cystic echinococcosis and its relationship with IL-10. (21923667)
2011
13
A case of pulmonary and hepatic cystic Echinococcosis of CE1 stage in a healthy Japanese female that was suspected to have been acquired during her stay in the United Kingdom. (21896804)
2011
14
Cystic echinococcosis in Romania: the pediatric approach. (21284521)
2011
15
Isolated type I pelvic cystic echinococcosis mimicking ovarian tumor. (22540100)
2011
16
Cystic echinococcosis of the pelvic bone with recurrences: a case report. (22072828)
2011
17
Programme for ultrasound diagnoses and treatment with albendazole of cystic echinococcosis in asymptomatic carriers: 10 years of follow-up of cases. (20832386)
2011
18
Epidemiology and epizootology of cystic echinococcosis in Romania 1862-2007. (20156088)
2010
19
TAP1 and TAP2 gene polymorphisms in childhood cystic echinococcosis. (20193774)
2010
20
Chemotherapy and surgery in children with cystic echinococcosis. (20574405)
2010
21
Evaluation of antibodies against hydatid cyst fluid antigens in the post-treatment follow-up of cystic echinococcosis patients. (19333201)
2009
22
Estimating the production losses due to cystic echinococcosis in ruminants in Turkey. (19482428)
2009
23
Molecular update on cystic echinococcosis in cattle and water buffaloes of southern Italy. (18234031)
2008
24
Post-surgical follow-up (by ELISA and immunoblotting) of cured versus non-cured cystic echinococcosis in young patients. (17767795)
2008
25
Heterogeneous distribution of human cystic echinococcosis after a long-term control program in NeuquAcn, Patagonia Argentina. (17317277)
2007
26
Liver cystic echinococcosis: which cysts are correlated with false negative indirect passive hemagglutination (IHA)? (17657919)
2007
27
Specific antibody detection in serum, urine and saliva samples for the diagnosis of cystic echinococcosis. (17335765)
2007
28
Cardiac manifestation of cystic echinococcosis: comparison of dual-source cardio-computed tomography and cardiac magnetic resonance imaging and their impact on disease management. (17984345)
2007
29
Comparative evaluation of western blotting in hepatic and pulmonary cystic echinococcosis. (17285854)
2006
30
Genotyping of human cystic echinococcosis in Xinjiang, PR China. (16836793)
2006
31
Cystic echinococcosis: analysis of the serological profile related to the risk factors in individuals without ultrasound liver changes living in an endemic area of TacuarembA^, Uruguay. (15830820)
2005
32
Postoperative changes in serum cytokines profile and nitric oxide levels in patients with cystic echinococcosis. (16218215)
2005
33
Epidemiological evaluations of the efficacy of slow-released praziquantel-medicated bars for dogs in the prevention and control of cystic echinococcosis in man and animals. (16231860)
2005
34
Echinococcus granulosus cattle strain identification in an autochthonous case of cystic echinococcosis in central Mexico. (15533292)
2004
35
Cystic echinococcosis in Sardinia: the current role of sheep. (16044699)
2004
36
Human cystic echinococcosis in Sardinia during the 20th century. (16044696)
2004
37
Cystic echinococcosis in the Berber of the Mid Atlas mountains, Morocco: new insights into the natural history of the disease in humans. (15257798)
2004
38
Evaluation of use of recombinant Em18 and affinity-purified Em18 for serological differentiation of alveolar echinococcosis from cystic echinococcosis and other parasitic infections. (12843091)
2003
39
Rapid dot-ELISA for the detection of specific antigens in the cyst fluid from human cases of cystic echinococcosis. (12537630)
2002
40
Prevalence, intensity, and fertility of ovine cystic echinococcosis in the central Peruvian Andes. (11579878)
2001
41
Estimating the economic effects of cystic echinococcosis. Part 3: Jordan, a developing country with lower-middle income. (11672465)
2001
42
Risk factors associated with human cystic echinococcosis in Jordan: results of a case-control study. (10723525)
2000
43
Native and recombinant antigens in the immunodiagnosis of human cystic echinococcosis. (11116435)
2000
44
Editorial response: Treatment of cystic echinococcosis--improving but still limited. (10476733)
1999
45
Short report: An imported case of cystic echinococcosis in Japan diagnosed by imaging and serology with confirmation of Echinococcus granulosus-specific DNA sequences. (9660465)
1998
46
T-lymphocyte cytokine mRNA expression in cystic echinococcosis. (9095287)
1997
47
Public health importance of cystic echinococcosis in Latin America. (9236943)
1997
48
Principles of the surgical approach in human liver cystic echinococcosis. (9095292)
1997
49
A retrospective study of human cystic echinococcosis in Jordan. (7487227)
1995
50
Multicentre clinical trials of benzimidazole-carbamates in human cystic echinococcosis (phase 2). (2692867)
1989

Variations for Cystic Echinococcosis

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Expression for genes affiliated with Cystic Echinococcosis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cystic Echinococcosis

Search GEO for disease gene expression data for Cystic Echinococcosis.

Pathways for genes affiliated with Cystic Echinococcosis

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Sources:
51PathCards, 54QIAGEN, 61Thomson Reuters, 56Reactome, 31KEGG, 39NCBI BioSystems Database, 58SinoBiological, 55R&D Systems, 62Tocris Bioscience, 5Cell Signaling Technology
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Pathways related to Cystic Echinococcosis according to GeneCards/GeneDecks:

(show all 45)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.9IL12B, TLR2
29.9IL12B, IL2RA
3
Show member pathways
9.7TAP2, TAP1, HLA-B
49.5TLR2, TLR4, IL12B
59.4HLA-B, HLA-DQB1, HLA-DRB1
6
Show member pathways
Immune response IL 12 induced IFN gamma production61
9.4IL12B, IL2RA, HLA-DRB1
7
Show member pathways
9.4HLA-DQB1, TLR2, TLR4
8
Show member pathways
9.4TLR2, TLR4, IL2RA
9
Show member pathways
9.3HLA-DQB1, HLA-DRB1, IL2RA
10
Show member pathways
9.2TLR2, IL17A, IL6
119.2IL10, HLA-DRB1, HLA-DQB1
12
Show member pathways
Immune response T cell receptor signaling pathway61
Immune response CD28 signaling61
Immune response ICOS pathway in T helper cell61
9.2IGHE, HLA-DQB1, HLA-DRB1
139.1IL6, TLR4, TLR2
14
Show member pathways
Transcription NF kB signaling pathway61
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response61
9.1IL6, TLR4, TLR2
159.1IL10, IL12B, IL6
169.1IL10, IL12B, IL6
17
Show member pathways
Immune response IL 22 signaling pathway61
G protein signaling N RAS regulation pathway61
9.1IL12B, IL2RA, HLA-DRB1, HLA-DQB1
189.0IL2RA, IL10, TAP1, TAP2
199.0HLA-DRB1, IL2RA, IL6
208.9TLR4, IL10, IL6
218.9HLA-B, HLA-DQB1, HLA-DRB1, IL10
22
Show member pathways
8.9TLR4, IL17A, IL12B, IL6
23
Show member pathways
8.9HLA-B, HLA-DQB1, HLA-DRB1, TAP1, TAP2
248.9IL6, IL12B, TLR4, TLR2
25
Show member pathways
IL23-mediated signaling events39
Immune response IL 10 signaling pathway61
Angiopoietin receptor Tie2-mediated signaling39
Development PDGF signaling via STATs and NF kB61
Development Angiopoietin Tie2 signaling61
8.8IL6, IL12B, IL10, IL17A
268.7IL6, IL2RA, TLR4, TLR2
27
Show member pathways
Type III interferon signaling39
8.7IL6, IL12B, IL10, IL2RA
288.7TLR4, IL10, IL12B, IL6
298.6HLA-DRB1, IL10, IL12B, IL6
308.6IL6, IL10, TLR4, TLR2
31
Show member pathways
8.6TLR2, TLR4, IL17A, IL12B, IL6
32
Show member pathways
8.6HLA-DQB1, HLA-DRB1, TLR2, TLR4, IL2RA
33
Show member pathways
8.4HLA-B, HLA-DQB1, HLA-DRB1, IL2RA, IL6
348.4HLA-B, HLA-DQB1, HLA-DRB1, IL2RA, IL6
358.4TLR2, TLR4, IL10, IL12B, IL6
36
Show member pathways
Toll-like receptor signaling pathway39
Regulation of toll-like receptor signaling pathway39
8.4TLR2, TLR4, IL10, IL12B, IL6
378.2HLA-B, HLA-DQB1, HLA-DRB1, TLR2, TLR4, TAP1
38
Show member pathways
IL27-mediated signaling events39
8.1TLR2, TLR4, IL17A, IL10, IL12B, IL6
398.0HLA-DQB1, HLA-DRB1, TLR2, TLR4, IL17A, IL6
40
Show member pathways
8.0TLR4, IL2RA, IL17A, IL10, IL12B, IL6
41
Show member pathways
8.0TLR2, TLR4, IL2RA, IL10, IL12B, IL6
427.6HLA-DQB1, HLA-DRB1, TLR2, TLR4, IL10, IL12B
43
Show member pathways
7.3HLA-DQB1, HLA-DRB1, TLR2, TLR4, IL17A, IL10
44
Show member pathways
6.9TAP1, IL6, IL12B, IL10, IL2RA, RNASE3
45
Show member pathways
6.1TAP2, HLA-B, TAP1, IL6, IL12B, IL2RA

Compounds for genes affiliated with Cystic Echinococcosis

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Sources:
46Novoseek, 12DrugBank, 52PharmGKB, 30IUPHAR, 62Tocris Bioscience, 25HMDB
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Compounds related to Cystic Echinococcosis according to GeneCards/GeneDecks:

(show top 50)    (show all 144)
idCompoundScoreTop Affiliating Genes
1solium4610.2MT-ATP6, HLA-B, MT-CO1
2glucuronoxylomannan469.6TLR4, TLR2, IL10
3gliadin469.4HLA-DQB1, RNASE3, IGHE
45 aminosalicylic acid469.3IL2RA, IL12B, IL10
5praziquantel46 1210.3IL10, RNASE3, IGHE
6hbd2469.3IL6, TLR2, TLR4
7poly(i-c)469.2TLR4, TLR2, IL6, IL12B
8montelukast46 52 30 1212.2IGHE, RNASE3, IL10, IL2RA
9latex469.1TLR4, IGHE, TLR2, HLA-B, RNASE3
10pentoxifylline46 1210.0IL6, IL12B, IL10, IL2RA
11polymyxin b469.0TLR2, TLR4, IL6, IL10
12ccl346 309.9IL10, TLR4, IL6, TLR2
13il-12468.8IL10, IL12B, IL6
14imiquimod46 62 30 1211.8IL10, IL12B, TLR4, TLR2, IL6
15peptidoglycan46 309.8IL6, TLR2, TLR4, IL12B, IL10
16ivig468.7IL10, IGHE, IL2RA, IL6
172,5-oligoadenylate468.7IL10, IL2RA, TLR4, IL6, HLA-B
18tacrolimus46 52 1210.7TLR2, HLA-B, TLR4, IL2RA, IL17A, IL10
19allergens468.7TLR4, HLA-DRB1, IGHE, IL10, RNASE3
20polysaccharide468.7IL2RA, RNASE3, TLR4, TLR2, HLA-B, IGHE
21h2o2468.7TLR4, TLR2, PRDX4, IL2RA, HLA-B, RNASE3
22oligonucleotide468.7RNASE3, HLA-DQB1, TAP1, TAP2, HLA-DRB1, HLA-B
23lipoteichoic acid468.6TLR4, IL10, IL12B, IL6, HLA-B, TLR2
24polyinosinic-polycytidylic acid468.6TLR4, TLR2, IL10, HLA-B, IL6, IL12B
25fibrinogen468.5RNASE3, HLA-B, IL6, TLR2, TLR4
26prednisolone46 30 1210.5IL2RA, IGHE, IL10, IL6, RNASE3
27calcitriol46 62 25 1211.5TLR4, TLR2, IL2RA, IL10, IL6
28lactate468.5RNASE3, IGHE, HLA-B, TLR4, IL6, PRDX4
29il 10468.4IL6, TLR4, IL2RA, IL10, IL12B, TLR2
30sb 20358046 629.4TLR4, IL6, IL12B, IL10, IL17A, TLR2
31n acetylcysteine468.4IL2RA, TLR4, IGHE, IL6, RNASE3
32ifn-alpha468.4TLR4, TAP1, IL2RA, IL17A, IL10, IL6
33creatinine468.3RNASE3, IGHE, IL6, IL17A, HLA-B, IL2RA
34aspartate468.3HLA-DQB1, TLR4, HLA-B, IL2RA, IGHE, IL10
35infliximab46 52 1210.2IGHE, TLR4, IL2RA, IL10, IL6, IL17A
36atp46 309.0PRDX4, MT-CO1, MT-ATP6, TAP2, HLA-DRB1, HLA-B
37endotoxin468.0TLR4, TLR2, HLA-B, RNASE3, IL12B, IL6
38cycloheximide468.0TLR2, IL10, IL6, IL12B, IGHE, TLR4
39nitric oxide46 25 1210.0IL17A, IL10, IL6, RNASE3, TLR4, TLR2
40vitamin d467.9IL6, IL12B, IGHE, TLR2, IL10, TLR4
41histamine46 30 259.9IL2RA, RNASE3, TLR4, TLR2, IGHE, IL10
42alanine467.8HLA-DRB1, TLR2, TLR4, IL6, TAP1, TAP2
43methotrexate52 46 129.7IL17A, IGHE, HLA-DRB1, TLR4, IL6, IL10
44rantes467.7IL2RA, IL10, IL17A, IL6, RNASE3, TLR4
45pge2467.6RNASE3, TLR4, IL6, IL12B, IL10, IL17A
46vegf467.5IL6, TLR4, IGHE, TLR2, RNASE3, IL2RA
47lipid467.4PRDX4, RNASE3, TLR2, HLA-B, TLR4, EEF1D
48cyclosporin a46 30 629.4IGHE, HLA-B, TLR2, TLR4, IL6, IL10
49dexamethasone46 52 30 1210.3IL6, IL10, IGHE, HLA-B, TLR2, TLR4
50tyrosine466.7HLA-DRB1, HLA-DQB1, HLA-B, TLR2, EEF1D, IL2RA

GO Terms for genes affiliated with Cystic Echinococcosis

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Sources:
17Gene Ontology
See all sources

Cellular components related to Cystic Echinococcosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1TAP complexGO:0428259.9TAP2, TAP1
2MHC class II protein complexGO:0426139.6HLA-DQB1, HLA-DRB1
3integral component of lumenal side of endoplasmic reticulum membraneGO:0715569.6HLA-B, HLA-DQB1, HLA-DRB1
4ER to Golgi transport vesicle membraneGO:0125079.5HLA-DRB1, HLA-DQB1, HLA-B
5extracellular spaceGO:0056158.6IL6, IL12B, IL10, IL17A, PRDX4
6external side of plasma membraneGO:0098978.1IL6, IL17A, IL2RA, TLR4, TLR2, HLA-DRB1
7plasma membraneGO:0058867.5HLA-B, HLA-DQB1, HLA-DRB1, TLR2, TLR4, IL2RA

Biological processes related to Cystic Echinococcosis according to GeneCards/GeneDecks:

(show all 49)
idNameGO IDScoreTop Affiliating Genes
1cytosol to ER transportGO:04696710.3TAP2, TAP1
2oligopeptide transmembrane transportGO:03567210.3TAP2, TAP1
3intracellular transport of viral protein in host cellGO:01906010.3TAP2, TAP1
4antigen processing and presentation of endogenous peptide antigen via MHC class IGO:01988510.3TAP2, TAP1
5peptide transportGO:01583310.3TAP1, TAP2
6cellular response to lipoteichoic acidGO:07122310.1TLR2, TLR4
7positive regulation of macrophage cytokine productionGO:06090710.1TLR2, TLR4
8immunoglobulin production involved in immunoglobulin mediated immune responseGO:00238110.0HLA-DRB1, HLA-DQB1
9positive regulation of tumor necrosis factor biosynthetic processGO:04253510.0TLR4, TLR2
10antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentGO:00247910.0HLA-B, TAP1, TAP2
11antigen processing and presentation of exogenous peptide antigen via MHC class IGO:04259010.0TAP2, TAP1, HLA-B
12positive regulation of nitric-oxide synthase biosynthetic processGO:05177010.0TLR4, TLR2
13positive regulation of osteoclast differentiationGO:04567210.0IL17A, IL12B
14detection of bacteriumGO:01604510.0HLA-B, HLA-DRB1
15humoral immune response mediated by circulating immunoglobulinGO:00245510.0HLA-DQB1, HLA-DRB1
16I-kappaB phosphorylationGO:00725210.0TLR2, TLR4, PRDX4
17antigen processing and presentation of peptide antigen via MHC class IGO:00247410.0TAP2, TAP1, HLA-B
18negative regulation of interleukin-17 productionGO:0327009.9IL12B, TLR4, TLR2
19positive regulation of interleukin-10 productionGO:0327339.9TLR2, TLR4, IL12B
20positive regulation of NF-kappaB import into nucleusGO:0423469.9IL12B, TLR4, TLR2
21positive regulation of interleukin-12 productionGO:0327359.9IL12B, TLR4, TLR2
22positive regulation of tumor necrosis factor productionGO:0327609.9TLR2, TLR4, IL12B
23positive regulation of inflammatory responseGO:0507299.9IL12B, TLR4, TLR2
24positive regulation of T cell mediated cytotoxicityGO:0019169.9HLA-B, IL12B, TAP1, TAP2
25positive regulation of MHC class II biosynthetic processGO:0453489.9TLR4, IL10
26negative regulation of interleukin-12 productionGO:0326959.9IL10, TLR2
27negative regulation of growth of symbiont in hostGO:0441309.8TLR2, IL10, IL12B
28inflammatory response to antigenic stimulusGO:0024379.8HLA-DRB1, IL2RA
29interferon-gamma-mediated signaling pathwayGO:0603339.8HLA-DRB1, HLA-DQB1, HLA-B
30T-helper 1 type immune responseGO:0420889.8IL12B, TLR4, HLA-DRB1
31positive regulation of interleukin-8 productionGO:0327579.7TLR4, TLR2
32positive regulation of interferon-beta productionGO:0327289.7TLR4, TLR2
33defense response to protozoanGO:0428329.7IL6, IL12B
34cellular response to lipopolysaccharideGO:0712229.7TLR4, IL10, IL12B
35defense response to Gram-negative bacteriumGO:0508299.6TLR4, IL12B, IL6
36positive regulation of activated T cell proliferationGO:0421049.6IL12B, IL2RA
37positive regulation of chemokine productionGO:0327229.6TLR2, TLR4, IL6
38positive regulation of nitric oxide biosynthetic processGO:0454299.5TLR2, TLR4, IL6
39negative regulation of T cell proliferationGO:0421309.5HLA-DRB1, IL2RA, IL10
40defense response to bacteriumGO:0427429.5TLR4, RNASE3, IL10
41positive regulation of interleukin-6 productionGO:0327559.5IL6, TLR4, TLR2
42negative regulation of interferon-gamma productionGO:0326899.5HLA-DRB1, TLR4, IL10
43negative regulation of interleukin-6 productionGO:0327159.4IL10, TLR4
44response to insulinGO:0328689.4TLR2, IL10, IL6
45positive regulation of NF-kappaB transcription factor activityGO:0510929.3IL6, TLR4, TLR2
46cytokine-mediated signaling pathwayGO:0192219.2HLA-B, HLA-DQB1, HLA-DRB1, IL6
47inflammatory responseGO:0069549.0IL6, IL10, IL17A, TLR2
48positive regulation of transcription from RNA polymerase II promoterGO:0459448.6TLR2, TLR4, IL17A, IL10, IL6
49immune responseGO:0069558.0IL17A, IGHE, HLA-B, HLA-DQB1, HLA-DRB1, TLR2

Molecular functions related to Cystic Echinococcosis according to GeneCards/GeneDecks:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1peptide transporter activityGO:01519710.1TAP2, TAP1
2MHC class Ib protein bindingGO:02302910.1TAP2, TAP1
3tapasin bindingGO:04698010.1TAP2, TAP1
4oligopeptide-transporting ATPase activityGO:01542110.1TAP1, TAP2
5TAP1 bindingGO:04697810.0TAP2, TAP1
6TAP2 bindingGO:0469799.9TAP2, TAP1
7lipopolysaccharide receptor activityGO:0018759.9TLR4, TLR2
8MHC class I protein bindingGO:0422889.6TAP2, TAP1
9MHC class II receptor activityGO:0323959.6HLA-DQB1, HLA-DRB1
10peptide antigen bindingGO:0426059.5TAP2, TAP1, HLA-DRB1, HLA-B
11growth factor activityGO:0080839.1IL6, IL12B, IL10
12cytokine activityGO:0051259.0IL17A, IL10, IL12B, IL6

Products for genes affiliated with Cystic Echinococcosis

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Sources for Cystic Echinococcosis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet