MCID: CYS001
MIFTS: 87

Cystic Fibrosis malady

Categories: Genetic diseases, Rare diseases, Metabolic diseases, Gastrointestinal diseases, Liver diseases, Reproductive diseases, Respiratory diseases, Endocrine diseases

Aliases & Classifications for Cystic Fibrosis

About this section
Sources:
50OMIM, 33LifeMap Discovery®, 11Disease Ontology, 69Wikipedia, 46NIH Rare Diseases, 23GeneTests, 24Genetics Home Reference, 13DISEASES, 52Orphanet, 68UniProtKB/Swiss-Prot, 25GTR, 12diseasecard, 48Novoseek, 36MedlinePlus, 37MeSH, 66UMLS, 28ICD10, 30ICD9CM, 43NCIt, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 35MedGen, 60SNOMED-CT, 62The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Cystic Fibrosis:

Name: Cystic Fibrosis 50 33 11 69 46 23 24 13 52 68 25 12 48 36 37 66
Mucoviscidosis 11 46 23 24 52 68
Pseudomonas Aeruginosa Chronic Infection by, in Cystic Fibrosis 50
 
Cystic Fibrosis Lung Disease, Modifier of 50
Fibrocystic Disease of Pancreas 24
Cystic Fibrosis of Pancreas 24

Characteristics:

Orphanet epidemiological data:

52
cystic fibrosis:
Inheritance: Autosomal recessive; Age of onset: All ages; Age of death: adult,young Adult

HPO:

62
cystic fibrosis:
Inheritance: autosomal recessive inheritance


Classifications:



External Ids:

OMIM50 219700
Disease Ontology11 DOID:1485
ICD1028 E84, E84.9
ICD9CM30 277.0
MeSH37 D003550
NCIt43 C2975
Orphanet52 ORPHA586
ICD10 via Orphanet29 E84.0, E84.1, E84.8 E84.9, more
MESH via Orphanet38 D003550
UMLS via Orphanet67 C0010674
MedGen35 C0010674

Summaries for Cystic Fibrosis

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MedlinePlus:36 Cystic fibrosis (cf) is an inherited disease of the mucus and sweat glands. it affects mostly your lungs, pancreas, liver, intestines, sinuses, and sex organs. cf causes your mucus to be thick and sticky. the mucus clogs the lungs, causing breathing problems and making it easy for bacteria to grow. this can lead to repeated lung infections and lung damage. the symptoms and severity of cf can vary. some people have serious problems from birth. others have a milder version of the disease that doesn't show up until they are teens or young adults. sometimes you will have few symptoms, but later you may have more symptoms. cf is diagnosed through various tests, such as gene, blood, and sweat tests. there is no cure for cf, but treatments have improved greatly in recent years. in the past, most deaths from cf were in children and teenagers. today, with improved treatments, some people who have cf are living into their forties, fifties, or older. treatments may include chest physical therapy, nutritional and respiratory therapies, medicines, and exercise. nih: national heart, lung, and blood institute

MalaCards based summary: Cystic Fibrosis, also known as cf, is related to bronchiectasis with or without elevated sweat chloride 2 and bronchiectasis with or without elevated sweat chloride 3, and has symptoms including abnormality of the pancreas, malabsorption and recurrent respiratory infections. An important gene associated with Cystic Fibrosis is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator), and among its related pathways are Cytokine production by Th17 cells in CF and Spinal Cord Injury. The drugs acetylcysteine and amiloride have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and pancreas, and related mouse phenotypes are digestive/alimentary and homeostasis/metabolism.

Disease Ontology:11 An autosomal recessive disease that is characterized by the buildup of thick, sticky mucus that can damage many organs.

NIH Rare Diseases:46 Cystic fibrosis (cf) is an inherited condition that causes mucus to build up and clog some of the organs in the body, particularly in the lungs and pancreas. when mucus clogs the lungs, it can make breathing very difficult. the thick mucus also causes bacteria to get stuck in the airways, which causes inflammation and infections. these infections can cause chronic coughing, and wheezing. over time, mucus buildup and infections can lead to permanent lung damage, including the formation of scar tissue (fibrosis) and cysts in the lungs. mucus can also block the digestive tract and pancreas, leading to digestive problems. cf is caused by mutations in the cftr gene and is inherited in an autosomal recessive pattern. last updated: 4/4/2013

UniProtKB/Swiss-Prot:68 Cystic fibrosis: A common generalized disorder of the exocrine glands which impairs clearance of secretions in a variety of organs. It is characterized by the triad of chronic bronchopulmonary disease (with recurrent respiratory infections), pancreatic insufficiency (which leads to malabsorption and growth retardation) and elevated sweat electrolytes. It is the most common genetic disease in Caucasians, with a prevalence of about 1 in 2'000 live births. Inheritance is autosomal recessive.

Genetics Home Reference:24 Cystic fibrosis is an inherited disease characterized by the buildup of thick, sticky mucus that can damage many of the body's organs. The disorder's most common signs and symptoms include progressive damage to the respiratory system and chronic digestive system problems. The features of the disorder and their severity varies among affected individuals.

OMIM:50 Formerly known as cystic fibrosis of the pancreas, this entity has increasingly been labeled simply 'cystic fibrosis.'... (219700) more...

Wikipedia:69 Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver,... more...

Related Diseases for Cystic Fibrosis

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Diseases related to Cystic Fibrosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 340)
idRelated DiseaseScoreTop Affiliating Genes
1bronchiectasis with or without elevated sweat chloride 233.9SCNN1A, SCNN1B, SCNN1G
2bronchiectasis with or without elevated sweat chloride 333.7CFTR, SCNN1A, SCNN1B, SCNN1G
3pulmonary fibrosis31.4SCNN1A, SCNN1B, SCNN1G
4tropical calcific pancreatitis30.1ABCC10, CFTR, ELANE
5congenital bilateral absence of vas deferens29.7ABCC10, CFTR, CLCA1, CLCA2, CLCA4, CXCL8
6cystic fibrosis with helicobacter pylori gastritis, megaloblastic anemia, and mental retardation12.2
7follicular hamartoma-alopecia-cystic fibrosis syndrome12.0
8bronchiectasis with or without elevated sweat chloride 111.3
9lubani-al saleh-teebi syndrome11.2
10aseptic osteitis11.1CFTR, SCNN1A, SCNN1B, SCNN1G
11choanal atresia11.1CFTR, CXCL8, ELANE, SCNN1A, SCNN1B, SCNN1G
12laryngeal tuberculosis11.1CFTR, CXCL8, ELANE, TGFB1
13chd2-related neurodevelopmental disorders11.1CFTR, TGFB1
14fundus dystrophy11.1CFTR, CXCL8, ELANE, TGFB1
15lymphopenia11.1CFTR, CXCL8, ELANE
16congenital fibrosis of the extraocular muscles 1a11.1CFTR, TGFB1
17pancreatitis11.0
18bronchiectasis11.0
19nonspecific interstitial pneumonia11.0CXCL8, ELANE, TGFB1
20allergic bronchopulmonary aspergillosis11.0
21perianal skin paget's disease11.0CXCL8, S100A8, TGFB1
22aspergillosis11.0
23palmoplantar keratosis11.0CXCL8, DEFB1, ELANE
24bladder disease11.0CLCA1, CLCA2, CLCA4
25meconium ileus10.9
26basaloid squamous cell carcinoma10.9CXCL8, ELANE, TGFB1
27cardiocranial syndrome10.9CXCL8, ELANE
28lymphangiectasia, intestinal10.8CXCL8, ELANE
29orbital plasma cell granuloma10.8CXCL8, ELANE
30chronic rhinitis10.8CXCL8, ELANE, FCGR2A
31exocrine pancreatic insufficiency10.7
32addison's disease10.7CXCL8, TGFB1
33pancreatic ductal adenocarcinoma10.7
34hyperuricemic nephropathy, familial juvenile 110.6ABCC10, CFTR, SCNN1B
35lung disease10.6
36hyperlysinemia10.6ABCC10, CFTR
37proliferative glomerulonephritis10.5ELANE, TGFB1
38stenotrophomonas maltophilia infection10.5
39shwachman-diamond syndrome10.4
40respiratory failure10.4
41keratomalacia10.4
42nontuberculous mycobacterial lung disease10.4
43mycobacterium abscessus10.4
44liver disease10.3
45diabetes mellitus, noninsulin-dependent10.3
46alcoholic hepatitis10.3
47chromophobe renal cell carcinoma10.3
48renal oncocytoma10.3
49asthma10.3
50intestinal obstruction10.3

Graphical network of the top 20 diseases related to Cystic Fibrosis:



Diseases related to cystic fibrosis

Symptoms for Cystic Fibrosis

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Symptoms by clinical synopsis from OMIM:

219700

Clinical features from OMIM:

219700

Symptoms:

 52 (show all 8)
  • exocrine pancreatic insufficiency
  • malabsorption
  • recurrent respiratory infections
  • pulmonary fibrosis
  • hepatomegaly
  • biliary cirrhosis
  • immunodeficiency
  • hypogammaglobulinemia

HPO human phenotypes related to Cystic Fibrosis:

(show all 21)
id Description Frequency HPO Source Accession
1 abnormality of the pancreas hallmark (90%) HP:0001732
2 malabsorption hallmark (90%) HP:0002024
3 recurrent respiratory infections hallmark (90%) HP:0002205
4 pulmonary fibrosis hallmark (90%) HP:0002206
5 decreased antibody level in blood hallmark (90%) HP:0004313
6 exocrine pancreatic insufficiency common (75%) HP:0001738
7 hepatomegaly occasional (7.5%) HP:0002240
8 failure to thrive HP:0001508
9 cor pulmonale HP:0001648
10 dehydration HP:0001944
11 rectal prolapse HP:0002035
12 asthma HP:0002099
13 bronchiectasis HP:0002110
14 hypercalciuria HP:0002150
15 biliary cirrhosis HP:0002613
16 male infertility HP:0003251
17 meconium ileus HP:0004401
18 chronic lung disease HP:0006528
19 recurrent pneumonia HP:0006532
20 recurrent bronchopulmonary infections HP:0006538
21 elevated sweat chloride HP:0012236

UMLS symptoms related to Cystic Fibrosis:


coughing, hemoptysis, snoring, wheezing

Drugs & Therapeutics for Cystic Fibrosis

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FDA approved drugs:

id Drug Name Active Ingredient(s)16 Company Approval Date
1
Cayston16 AZTREONAM Gilead February 2010
FDA Label: Cayston
Disease/s that Drug Treats:cystic fibrosis patients with Pseudomonas aeruginosa
Indications and Usage:16 CAYSTON is a monobactam antibacterial indicated to improve respiratory symptoms in cystic fibrosis (CF) patients with Pseudomonas aeruginosa. Safety and effectiveness have not been established in pediatric patients below the age of 7 years, patients with FEV1 <25% or >75% predicted, or patients colonized with Burkholderia cepacia. (1)
DrugBank Targets:14 Penicillin-binding protein 3|Beta-lactamase
Mechanism of Action:16 
Target: penicillin binding proteins of susceptible bacteria
Action: inhibition of bacterial cell wall synthesis
FDA: Aztreonam is an antibacterial drug [see Clinical Pharmacology (12.4)]. Aztreonam exhibits activity in vitro against Gram-negative aerobic pathogens including P. aeruginosa. Aztreonam binds to penicillinbinding proteins of susceptible bacteria, which leads to inhibition of bacterial cell wall synthesis and death of the cell. Aztreonam activity is not decreased in the presence of CF lung secretions.
2
Kalydeco16 IVACAFTOR Vertex Pharmaceuticals January of 2012
FDA Label: Kalydeco
Disease/s that Drug Treats:cystic fibrosis with the G551D mutation in the CFTR gene
Indications and Usage:16 KALYDECO is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator indicated for the treatment of cystic fibrosis (CF) in patients age 6 years and older who have one of the following mutations in the CFTR gene: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N, or S549R. KALYDECO is indicated for the treatment of CF in patients age 6 years and older who have an R117H mutation in the CFTR gene. If the patient’s genotype is unknown, an FDA-cleared CF mutation test should be used to detect the presence of a CFTR mutation followed by verification with bi-directional sequencing when recommended by the mutation test instructions for use. (1) Limitations of Use: * Not effective in patients with CF who are homozygous for the F508del mutation in the CFTR gene. (1, 14)
DrugBank Targets:14 Cystic fibrosis transmembrane conductance regulator
Mechanism of Action:16 
Target: cystic fibrosis transmembrane conductance regulator (CFTR)
Action: potentiator
FDA: Ivacaftor is a potentiator of the CFTR protein. The CFTR protein is a chloride channel present at the surface of epithelial cells in multiple organs. Ivacaftor facilitates increased chloride transport by potentiating the channel-open probability (or gating) of the CFTR protein. In vitro, ivacaftor increased CFTR-mediated transepithelial current (IT) in rodent cells expressing the G551D-CFTR protein following addition of a cyclic adenosine monophosphate (cAMP) agonist with an EC50 of 100 ± 47 nM; however, ivacaftor did not increase IT in the absence of cAMP agonist. Ivacaftor also increased IT in human bronchial epithelial cells expressing G551D-CFTR protein following addition of a cAMP agonist by 10-fold with an EC50 of 236 ± 200 nM. Ivacaftor increased the open probability of G551D-CFTR protein in single channel patch clamp experiments using membrane patches from rodent cells expressing G551D-CFTR protein by 6-fold versus untreated cells after addition of PKA and ATP. In addition to G551D-CFTR, ivacaftor increased the channel-open probability of other mutant CFTR forms expressed in rodent cells, resulting in enhanced CFTR-mediated IT. These mutant CFTR forms included G178R-, S549N-, S549R-, G551S-, G970R-, G1244E-, S1251N-, S1255P-, and G1349D-CFTR. Ivacaftor also potentiated the channel-open probability of R117H-CFTR, which has low channel-open probability (gating) and reduced channel current amplitude (conductance) compared to normal CFTR. In vitro responses do not necessarily correspond to in vivo pharmacodynamic response or clinical benefit.
3
Orkambi16 IVACAFTOR; LUMACAFTOR Vertex Pharmaceuticals July 2015
FDA Label: Orkambi
Disease/s that Drug Treats:cystic fibrosis
Indications and Usage:16 ORKAMBI is a combination of lumacaftor and ivacaftor, a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, indicated for the treatment of cystic fibrosis (CF) in patients age 12 years and older who are homozygous for the F508del mutation in the CFTR gene. If the patient’s genotype is unknown, an FDA-cleared CF mutation test should be used to detect the presence of the F508del mutation on both alleles of the CFTR gene. (1) Limitations of Use: The efficacy and safety of ORKAMBI have not been established in patients with CF other than those homozygous for the F508del mutation. (1)
DrugBank Targets:14 Cystic fibrosis transmembrane conductance regulator
Mechanism of Action:16 
Target: cystic fibrosis transmembrane conductance regulator (CFTR)
Action: oral regulators
FDA: The CFTR protein is a chloride channel present at the surface of epithelial cells in multiple organs. The F508del mutation results in protein misfolding, causing a defect in cellular processing and trafficking that targets the protein for degradation and therefore reduces the quantity of CFTR at the cell surface. The small amount of F508del-CFTR that reaches the cell surface is less stable and has low channel-open probability (defective gating activity) compared to wild-type CFTR protein. Lumacaftor improves the conformational stability of F508del-CFTR, resulting in increased processing and trafficking of mature protein to the cell surface. Ivacaftor is a CFTR potentiator that facilitates increased chloride transport by potentiating the channel-open probability (or gating) of the CFTR protein at the cell surface. In vitro studies have demonstrated that both lumacaftor and ivacaftor act directly on the CFTR protein in primary human bronchial epithelial cultures and other cell lines harboring the F508del-CFTR mutation to increase the quantity, stability, and function of F508del-CFTR at the cell surface, resulting in increased chloride ion transport. In vitro responses do not necessarily correspond to in vivo pharmacodynamic response or clinical benefit.
4
Pulmozyme16 DORNASE ALFA Genentech December 1996| March 1998
FDA Label: Pulmozyme
Disease/s that Drug Treats:cystic fibrosis
Indications and Usage:16 PULMOZYME is a recombinant DNase enzyme indicated in conjunction with standard therapies for the management of cystic fibrosis (CF) patients to improve pulmonary function. (1)
DrugBank Targets:14 DNA
Mechanism of Action:16 
Target: -
Action: -
FDA: PULMOZYME is recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. In preclinical in vitro studies, PULMOZYME hydrolyzes the DNA in sputum of CF patients and reduces sputum viscoelasticity. In CF patients, retention of viscous purulent secretions in the airways contributes both to reduced pulmonary function and to exacerbations of infection. Purulent pulmonary secretions contain very high concentrations of extracellular DNA released by degenerating leukocytes that accumulate in response to infection.
5
Tobi16 TOBRAMYCIN PathoGenesis December 1997
FDA Label: Tobi
Disease/s that Drug Treats:cystic fibrosis
Indications and Usage:16 TOBI is indicated for the management of cystic fibrosis patients with P. aeruginosa. Safety and efficacy have not been demonstrated in patients under the age of 6 years, patients with forced expiratory volume in 1 second (FEV1) <25% or >75% predicted, or patients colonized with Burkholderia cepacia (see CLINICAL STUDIES).
DrugBank Targets:14 30S ribosomal protein S12|16S rRNA
Mechanism of Action:16 
Target: -
Action: -
FDA: Tobramycin is an aminoglycoside antibiotic produced by Streptomyces tenebrarius. (1) It acts primarily by disrupting protein synthesis, leading to altered cell membrane permeability, progressive disruption of the cell envelope, and eventual cell death.(3) Tobramycin has in vitro activity against a wide range of gram-negative organisms including Pseudomonas aeruginosa. It is bactericidal at concentrations equal to or slightly greater than inhibitory concentrations.

Drugs for Cystic Fibrosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 190)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AztreonamPhase 4, Phase 3, Phase 24478110-38-05362041, 5742832
Synonyms:
(Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid
2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene]amino}oxy)-2-methylpropanoic acid
2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-{[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino}-2-oxoethylidene]amino}oxy)-2-methylpropanoic acid
2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid
78110-38-0
AC-4330
AC1NX3U2
AZT
Ambap78110-38-0
Azactam
Aztreonam
Aztreonamum
Aztréonam
BIDD:GT0765
BPBio1_000121
BRD-K62607865-001-03-0
 
BSPBio_000109
CHEBI:161680
CHEMBL158
CID5742832
HMS1568F11
HMS2090K09
MolPort-003-886-345
Monobactam, SQ 26776, Squibb 26776, Aztreonam
NCGC00179656-01
NSC646279
Prestwick2_000185
Prestwick3_000185
Prestwick_914
Primbactam
S1505_Selleck
SQ-26776
[2S-[2alpha,3beta(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid
aztreonam
2Risedronate SodiumPhase 498115436-72-1
3
TamoxifenPhase 436810540-29-12733526
Synonyms:
(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene
(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(4-(1,2-diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine
(Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine (IUPAC)
(Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE
(Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
,citrate
1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-p-.beta.-Dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
10540-29-1
1ya4
2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
54965-24-1 (citrate)
AC1MBZ3R
Apo-Tamox
Apo-tamox
BIDD:ER0008
BIDD:GT0009
BIDD:PXR0003
BPBio1_000278
BRD-K93754473-001-02-9
BRD-K93754473-048-05-3
BSPBio_000252
BSPBio_001150
BSPBio_001982
C07108
C26H29NO
CCRIS 3275
CHEBI:41774
CHEMBL83
CID2733526
Citofen
Crisafeno
D08559
DB00675
Diemon
EINECS 234-118-0
Gen-Tamoxifen
Gen-tamoxifen
HMS1362J11
HMS1792J11
HMS1990J11
HMS2090N08
HSDB 6782
ICI 47699
ICI-46,474
ICI-47699
IDI1_000258
IDI1_002170
Istubol
Kessar
L024126
LS-393
Lopac0_001203
MLS001332535
MLS001332536
MolPort-003-850-384
 
NCGC00024928-01
NCGC00024928-03
NCGC00024928-04
NCGC00024928-05
NCGC00024928-07
NCGC00024928-08
NCGC00024928-09
NCGC00024928-12
NSC727681
Noltam
Nolvadex
Nolvadex-D
Nourytam
Novaldex
Novo-Tamoxifen
Oncomox
PMS-Tamoxifen
Pms-Tamoxifen
Prestwick2_000146
Prestwick3_000146
QTL1_000079
Retaxim
SMR000059172
ST50511785
Spectrum5_001417
Spectrum5_002043
T5648_SIGMA
TAMOXIFEN (TAMOXIFEN CITRATE (54965-24-1))
TRANS FORM OF TAMOXIFEN
Tamizam
Tamofen
Tamone
Tamoplex (TN)
Tamoxasta
Tamoxen
Tamoxifen
Tamoxifen (INN)
Tamoxifen (TN)
Tamoxifen (Z)
Tamoxifen Citrate
Tamoxifen [INN:BAN]
Tamoxifen and its salts
Tamoxifene
Tamoxifene [INN-French]
Tamoxifeno
Tamoxifeno [INN-Spanish]
Tamoxifenum
Tamoxifenum [INN-Latin]
Tamoxifène
Tocris-0999
Tomaxithen
Trans-Tamoxifen
UNII-094ZI81Y45
UPCMLD-DP027
Valodex
Zemide
cMAP_000044
nchembio.140-comp7
nchembio.76-comp1
nchembio732-comp3
tamoxifen
trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
trans-Tamoxifen
4
MethylprednisolonePhase 4, Phase 1, Phase 2111883-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
5
NicotinePhase 4101654-11-5942, 89594
Synonyms:
(−
(+)-Nicotine
(+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine
(+-)-Nicotine
(-)-3-(1-Methyl-2-pyrrolidyl)pyridine
(-)-3-(N-Methylpyrrolidino)pyridine
(-)-Nicotine
(-)-Nicotine solution
(2S) 3-(1-Methyl-pyrrolidin-2-yl)-pyridine
(R)-3-(1-Methyl-2-pyrrolidinyl)pyridine
(R,S)-Nicotine
(R,S)-nicotine
(RS)-nicotine
(S)-(-)-NICOTINE, 3-[(2S)-1-METHYL-2-PYRROLIDINYL] PYRIDINE
(S)-(-)-Nicotine
(S)-3-(1-methylpyrrolidin-2-yl)pyridine
(S)-3-(N-methylpyrrolidin-2-yl)pyridine
(S)-Nicotine
(±)-nicotine
)-1-Methyl-2-(3-pyridyl)pyrrolidine
)-Nicotine
)-Nicotine solution
1-Methyl-2-(3-pyridal)-Pyrrolidine
1-Methyl-2-(3-pyridal)-pyrrolidene
1-Methyl-2-(3-pyridiyl)pyrrolidine
1-Methyl-2-(3-pyridyl)pyrrolidine
1uw6
2'-beta-H-Nicotine
3-(1-Methyl-2-pyrollidinyl)pyridine
3-(1-Methyl-2-pyrrolidinyl)-Pyridine
3-(1-Methyl-2-pyrrolidinyl)pyridine
3-(1-Methylpyrrolidin-2-yl)pyridine
3-(2-(N-methylpyrrolidinyl))pyridine
3-(N-Methylpyrollidino)pyridine
3-(N-Methylpyrrolidino)pyridine
3-N-Methylpyrrolidine
3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
36733_FLUKA
36733_RIEDEL
434F7990-3240-4A43-ACEC-E6CC1E495FA0
46343_FLUKA
46343_RIEDEL
54-11-5
AC1L3I79
AC1Q3ZOC
AI3-03424
BB_NC-0777
BIDD:GT0599
BRD-K05395900-322-02-1
Black Leaf
Black Leaf 40
C00745
CCRIS 1637
CHEBI:17688
CHEMBL3
CID89594
CPD000059074
Campbell's Nico-Soap
Caswell No. 597
Commit
D-Nicotine
D03365
DL-tetrahydronicotyrine
Destruxol
Destruxol Orchid Spray
EINECS 200-193-3
ENT 3,424
EPA Pesticide Chemical Code 056702
Emo-Nik
Flux Maag
Fumeto bac
Fumetobac
HSDB 1107
Habitrol
Habitrol (TN)
L(-)-nicotine
L-3-(1-Methyl-2-pyrrolidyl)pyridine
 
L-Nicotine
LS-202
MLS001055457
MLS001335905
Mach-Nic
Methyl-2-pyrrolidinyl)pyridine
Micotine
MolPort-000-744-731
N3876_SIGMA
N5511_FLUKA
N5511_SIGMA
NCGC00090693-01
NCGC00090693-02
NCGC00090693-03
NCGC00090693-04
NCGC00090693-05
NCGC00090693-06
NCGC00090693-07
NCT
NICOTINE AND SALTS
NSC 5065
NSC97238
Niagara P.A. Dust
Nic-Sal
Nico-Dust
Nico-Fume
Nicocide
Nicoderm
Nicoderm Cq
Nicoderm Patch
Nicorette
Nicorette Plus
Nicotin
Nicotina
Nicotina [Italian]
Nicotine
Nicotine (USP)
Nicotine (compounds related to)
Nicotine Alkaloid
Nicotine Patch
Nicotine Polacrilex
Nicotine [BSI:ISO]
Nicotine [UN1654]
Nicotine [UN1654] [Poison]
Nicotine [USAN]
Nicotrol
Nicotrol Inhaler
Nicotrol Ns
Nictoine patch
Nikotin
Nikotin [German]
Nikotyna
Nikotyna [Polish]
Ortho N-4 Dust
Ortho N-5 Dust
PDSP1_000113
PDSP1_000465
PDSP2_000463
PDSP2_000555
Prostep
R)-(+)-Nicotine
RCRA waste no. P075
RCRA waste number P075
SAM002564224
SDCCGMLS-0066911.P001
SMR000059074
Tendust
Transdermal Nicotine
UN1654
a -N-Methylpyrrolidine
a-N-Methylpyrrolidine
alpha-N-Methylpyrrolidine
beta-Pyridyl-alpha-N-methyl pyrrolidine
beta-Pyridyl-alpha-N-methylpyrrolidine
bmse000105
delta-Nicotine
nicotine
nicotine replacement patch
6
PrednisolonePhase 4, Phase 1, Phase 2111850-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
7insulinPhase 4, Phase 3, Phase 2, Phase 1, Phase 04401
8
Insulin GlarginePhase 4, Phase 3509160337-95-1
Synonyms:
 
Insulin Glargine (rDNA origin)
Insulin glargine recombinant
9
DoxycyclinePhase 4, Phase 2232564-25-054671203
Synonyms:
(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(4S,4AR,5S,5ar,6R,12as)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
10597-92-9
17086-28-1 (mono-hydrate)
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)
24390-14-5
41411-66-9 (6-epimer, mono-hydrochloride)
5-Hydroxy-alpha-6-deoxytetracycline
564-25-0
6-Deoxyoxytetracycline
6-Deoxytetracycline
6-alpha-Deoxy-5-oxytetracycline
6-alpha-deoxy-5-oxytetracycline
69935-17-7 (mono-hydrochloride, di-hydrate)
6alpha-Deoxy-5-oxytetracycline
6α-deoxy-5-oxytetracycline
7164-70-7
7264-10-0
94088-85-4 (calcium salt (1:2))
AB08 (*Fosfatex)
AC1NQXW7
AC1NS4CW
AC1NUYS8
AC1O8PYM
Alti-Doxycycline
Apo-Doxy
Atridox
Azudoxat
BCBcMAP01_000024
BIDD:GT0146
BMY-28689
BPBio1_000951
BSPBio_000863
BSPBio_001936
BU-3839T
C06973
CHEBI:50845
CHEMBL1433
CID5281011
CID5353597
CID5463943
CID6713981
CPD001550033
D07876
DB00254
DMSC (*Fosfatex)
DOXCYCLINE ANHYDROUS
DOXY
DOXYCYCLINE CALCIUM
DOXYCYCLINE MONOHYDRATE
Deoxymykoin
DivK1c_000345
Dossiciclina
Dossiciclina [DCIT]
Doxcycline anhydrous
Doxiciclina
Doxiciclina [INN-Spanish]
Doxiciclina [Italian]
Doxitard
Doxivetin
Doxy-Caps
Doxy-Puren
Doxy-Tabs
Doxycen
Doxychel
Doxychel (TN)
Doxycin
Doxycyclin
Doxycycline (200mg/day) or Placebo
Doxycycline (INN)
 
Doxycycline (TN)
Doxycycline (anhydrous)
Doxycycline (internal use)
Doxycycline Hyclate
Doxycycline Monohydrate
Doxycycline anhydrous
Doxycycline hyclate
Doxycycline-Chinoin
Doxycyclinum
Doxycyclinum [INN-Latin]
Doxysol
Doxytec
Doxytetracycline
EINECS 209-271-1
GS-3065 (*monohydrate)
HMS2090E06
HSDB 3071
Hydramycin
IDI1_000345
Investin
Jenacyclin
KBio1_000345
KBio2_001287
KBio2_003855
KBio2_006423
KBio3_001156
KBioGR_001133
KBioSS_001287
LS-187766
LS-93868
Liviatin
Lopac0_000405
MolPort-002-507-423
Monodox
Monodox (*monohydrate)
NCGC00161602-01
NCGC00161602-03
NCGC00161602-04
NCGC00167961-01
NCGC00179395-01
NINDS_000345
NSC633557
Novo-Doxylin
Nu-Doxycycline
Oracea
Prestwick0_000852
Prestwick1_000852
Prestwick2_000852
Prestwick3_000852
Ronaxan
SAM002589932
SMP1_000107
SPBio_000246
SPBio_002784
STOCK1N-34341
Spanor
Spectrum2_000143
Spectrum3_000408
Spectrum4_000527
Spectrum5_000947
Spectrum_000807
Supracyclin
UNII-334895S862
UPCMLD-DP021
UPCMLD-DP021:001
Vibra-tabs
Vibramycin
Vibramycin (*monohydrate)
Vibramycin Novum
Vibramycine
Vibravenos
Vivox (*Hyclate)
alpha-6-Deoxy-5-hydroxytetracycline
alpha-6-Deoxyoxytetracycline
alpha-Doxycycline
doxycycline
10PREDNISOLONE ACETATEPhase 4, Phase 1, Phase 21118
11Clavulanic AcidPhase 4161
12
TicarcillinPhase 41034787-01-436921
Synonyms:
(2S,5R,6R)-6-[[(2R)-3-hydroxy-3-oxo-2-thiophen-3-ylpropanoyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-6-{[(2R)-2-carboxy-2-(3-thienyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-6-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
17778_FLUKA
34787-01-4
6beta-{[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino}-2,2-dimethylpenam-3alpha-carboxylic acid
AC1L1WMX
AC1Q5QWE
BRL-2288
C07139
C15H16N2O6S2
CHEBI:9587
CHEMBL1449
CID36921
D08593
DB01607
EINECS 252-213-5
LS-174491
MolPort-003-927-225
Prestwick0_001067
Prestwick1_001067
 
Prestwick2_001067
SPBio_002967
TICARCILLIN
TIPC
Ticarcilina
Ticarcilina [INN-Spanish]
Ticarcilina [inn-spanish]
Ticarcillin (INN)
Ticarcillin Supplement
Ticarcillin [INN:BAN]
Ticarcillin supplement
Ticarcilline
Ticarcilline [INN-French]
Ticarcilline [inn-french]
Ticarcillinum
Ticarcillinum [INN-Latin]
Ticarcillinum [inn-latin]
Ticillin [veterinary]
Ticillin [veterinary] (TN)
UNII-F93UJX4SWT
a-carboxy-3-thienylmethylpenicillin
alpha-Carboxy-3-thienylmethylpenicillin
alpha-carboxy-3-thienylmethylpenicillin
13
CeftazidimePhase 4, Phase 16278439-06-25481173
Synonyms:
(6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
7-[[2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
72558-82-8
7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-3-(pyridinium-1-ylmethyl)-3,4-didehydrocepham-4-carboxylate
AB00513848
AC1L1E5K
AC1L3MNA
AC1NUK7U
AC1NUN9Q
BIDD:GT0734
BRN 4344904
C06889
C2225
C22H22N6O7S2
CAZ
CEFTAZIDIME (ARGININE FORMULATION)
CHEBI:3508
CHEMBL201
CID2650
CID5481173
CID5484131
 
Ceftazidim
Ceftazidima
Ceftazidima [INN-Spanish]
Ceftazidime
Ceftazidime (INN)
Ceftazidime (TN)
Ceftazidime Sodium In Plastic Container
Ceftazidime anhydrous
Ceftazidime pentahydrate
Ceftazidimum
Ceftazidimum [INN-Latin]
Ceptaz
Ceptaz (TN)
D07654
DB00438
EINECS 276-715-9
Fortaz
Fortaz (TN)
Fortaz In Plastic Container
HMS2090M13
I06-1102
LS-132194
SN 401
UNII-9M416Z9QNR
ceftazidima
ceftazidime
ceftazidimum
14
AcetylcysteinePhase 4, Phase 2, Phase 1304616-91-112035
Synonyms:
(2R)-2-acetylamino-3-Sulfanylpropanoic acid
(R)-2-acetylamino-3-Mercaptopropanoic acid
(R)-Mercapturic acid
2-Acetylamino-3-mercapto-propionate
2-Acetylamino-3-mercapto-propionic acid
ACC
Acetadote
Acetilcisteina
Acetylcysteine
Acetylcysteinum
Fluimicil Infantil
Fluimucetin
Fluimucil
Flumucetin
 
Fluprowit
L-Acetylcysteine
L-alpha-acetamido-beta-Mercaptopropionic acid
Lysox
Mercapturic acid
Mucolysin
Mucomyst
N-ACETYL-L-cysteine
N-Acety-L-Cysteine
N-Acetyl-3-mercaptoalanine
N-Acetyl-L-(+)-cysteine
N-Acetylcysteine
N-acetylcysteine
NAC
Parvolex
Sodium 2-acetamido-3-mercaptopropionate
15
protease inhibitorsPhase 4, Phase 3, Phase 2, Phase 15157
Synonyms:
 
protease inhibitors
16
FosfomycinPhase 4, Phase 23123155-02-4446987
Synonyms:
(−
(-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid
(1R,2S)(-)-(1,2-Epoxypropyl)phosphonic acid disodium salt
(1R,2S)-Epoxypropylphosphonic acid
(1R,2S)-epoxypropylphosphonate
(1R,2S)-epoxypropylphosphonic acid
(2R-cis)-(3-Methyloxiranyl)phosphonic acid
(2R-cis)-(3-Methyloxiranyl)phosphonic acid disodium salt
)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid
1R-cis-(1,2-Epoxypropyl)phosphonic acid
23155-02-4
26016-99-9
34089_FLUKA
34089_RIEDEL
6F066DFF-696A-4A94-AF78-A28430EBE5BA
AC1L2JXY
AC1L9KC0
AC1Q1URS
AR-1I6648
BIDD:GT0448
BRN 1680831, Fosfocina
C06454
CHEBI:681859
CHEMBL1757
CID446987
CID73491
CPD0-1113
D02188
D04253
DB00828
Disodium (1R,2S)-(1,2-epoxypropyl)phosphonate
Disodium fosfomycin
Disodium phosphonomycin
EINECS 247-409-2
FCM
FOM-Na
FOSFOMYCIN
 
Fosfocina
Fosfocina disodium salt
Fosfomicina
Fosfomycin (USAN/INN)
Fosfomycin disodium
Fosfomycin disodium salt
Fosfomycin sodium
Fosfomycin sodium (JP15)
Fosfomycin sodium salt
Fosfomycine
Fosfomycinum
Fosfonomycin
Fosmicin S
Fosmicin S (TN)
I06-1211
L-cis-1,2-Epoxypropylphosphonic acid
L-cis-1,2-epoxypropylphosphonic acid
LS-106593
MK 955
MolPort-003-847-502
NSC 136017
P5396_SIGMA
Phosphomycin
Phosphomycin disodium salt
Phosphonemycin
Phosphonic acid, (3-methyloxiranyl)-, disodium salt, (2R-cis)- (9CI)
Phosphonomycin
Phosphonomycin disodium salt
Phosphonomycin sodium
Priomicina
Sodium fosfomycin
Veramina
ZINC19594585
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid
cis-(1R,2S)-Epoxypropylphosphonic acid
disodium[(2r,3s)-3-methyloxiran-2-yl]phosphonate
nchem.1024-comp6
phosphomycin
17
RifampicinPhase 4, Phase 2, Phase 132813292-46-15458213, 5381226
Synonyms:
1-b]furan-21-yl acetate
13292-46-1
3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin
3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin sv
3-(4-Methylpiperazinyliminomethyl)-rifamycin SV
3-(4-Methylpiperazinyliminomethyl)rifamycin SV
3-([(4-Methyl-1-piperazinyl)imino]methyl)rifamycin SV
3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV
3-[[(4-Methyl-1-piperazinyl)imino]-methyl]rifamycin
46713_FLUKA
46713_RIEDEL
62534-43-4
8-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
8-(4-Methylpiperazinyliminomethyl) rifamycin SV
8-[[(4-Methyl-1-piperazinyl)imino[methyl]rifamycin
8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin sv
8-[[(4-Methylpiperazinyl)imino]methyl]rifamycin sv
83907_FLUKA
83907_SIGMA
8CI)
AZT + Rifampin
Abrifam
Archidyn
Arficin
Arzide
BA-41166E
BIDD:PXR0014
BPBio1_000561
BSPBio_000509
Ba 41166
Ba 41166/E
Benemicin
Benemycin
Bio-0621
C06688
C43H58N4O12
CAS-13292-46-1
CCRIS 551
CHEBI:28077
CHEBI:455936
CHEMBL180
CID5381226
CID5388984
CID5458213
CID5702112
CID6604339
CID6708473
CID6842115
CID6912767
CID6913622
CPD001906767
D00211
DB01045
DRG-0109
Dione 21-acetate
Dipicin
DivK1c_000550
Doloresum
EINECS 236-312-0
Eremfat
Famcin
Fenampicin
HMS1569J11
HMS1920P08
HMS2089F12
HMS2092G09
HMS501L12
HSDB 3181
KBio1_000550
KBio2_000919
KBio2_003487
KBio2_006055
KBio3_003018
KBioGR_001780
KBioSS_000919
L-5103
L-5103 Lepetit
LS-7689
MLS000028552
MLS001148237
MLS001333745
MolPort-000-767-051
MolPort-002-513-586
MolPort-003-666-281
MolPort-006-395-891
NCGC00016699-01
NCGC00017365-01
NCGC00018178-01
NCGC00022678-03
NCGC00022678-04
NCGC00022678-05
NCGC00160500-01
 
NCI60_000309
NINDS_000550
NSC 113926
NSC-113926
NSC113926
Piperine & Rifampicin
Prestwick0_000525
Prestwick1_000525
Prestwick2_000525
Prestwick3_000525
Prestwick_833
R-Cin
R/AMP
R0079
R3501_SIAL
R3501_SIGMA
R5777_SIGMA
R7382_SIGMA
RAMP
RFP
RMP
Ramp
Reserpine & Rifampicin
Rf
Rfamipicin
Rifa
Rifadin
Rifadin (TN)
Rifadin I.V
Rifadin I.V.
Rifadin IV
Rifadin Iv
Rifadin, Rimactane, Rifampicin, Rifampin
Rifadine
Rifagen
Rifaldazin
Rifaldazine
Rifaldin
Rifam
Rifamicin AMP
Rifamor
Rifampicin
Rifampicin & EEP
Rifampicin & Propolis
Rifampicin (JP15/INN)
Rifampicin SV
Rifampicin [INN:BAN:JAN]
Rifampicina
Rifampicina [INN-Spanish]
Rifampicine
Rifampicine [French]
Rifampicinum
Rifampicinum [INN-Latin]
Rifampin
Rifampin (USP)
Rifampin [USAN]
Rifamsolin
Rifamycin
Rifamycin AMP
Rifamycin Amp
Rifaprodin
Rifcin
Rifinah
Rifobac
Rifoldin
Rifoldine
Riforal
Rimactan
Rimactane
Rimactane (TN)
Rimactazid
Rimactin
Rimactizid
Rimazid
Rimycin
Rofact
S1764_Selleck
SAM002264646
SMR000058322
SMR000653525
SPBio_002430
SPECTRUM1500529
STK080143
Sinerdol
Spectrum3_001837
Spectrum4_001250
Spectrum5_002018
Spectrum_000439
TNP00313
Tubocin
UNII-VJT6J7R4TR
WLN: V1 WQ A&1 E&1 E1UN- AT6N DNTJ D1
nchembio884-comp4
rifampin
18
MentholPhase 4, Phase 3, Phase 121842216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
19
ItraconazolePhase 4, Phase 2, Phase 114584625-61-655283
Synonyms:
(+-)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup 2)-1,2,4-triazolin-5-one
(+/-)-1-[( R *)- sec -butyl]-4-[ p -[4-[ p -[[(2 R *,4 S *)-2-(2,4-dichlorophenyl)-2-(1 H -1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-(DELTA) 2 1,2,4-triazolin-5-one mixture with (+/-)-1-[( R *)- sec -butyl]-4-[ p -[4- [ p -[[(2 S *,4 R *)-2-(2,4-dichlorophenyl)-2-(1 H -1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl] phenyl]-(DELTA) 2 -1,2,4-triazolin-5-one
(1)-cis-4-(4-(4-(4-((2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2,4-dihydro-2-sec-butyl-3H-1,2,4-triazol-3-one
2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one
2-butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
2-butan-2-yl-4-[4-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-pipera-zinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)
4-(4-{4-[4-({[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl}oxy)phenyl]piperazin-1-yl}phenyl)-2-(1-methylpropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
84604-65-9
84625-61-6
AC-542
AC1L1GQ5
AC1L1IRU
AC1OCEL7
AC1Q6EZ3
AKOS000280875
Ambap84625-61-6
BIDD:GT0796
BRN 6042047
C35H38Cl2N8O4
CHEBI:6076
CHEMBL22587
CHEMBL882
CID3793
CID55283
CID6917738
CID9961741
CPD000058959
Canadiol
D00350
DB01167
EINECS 283-347-2
FT-0082511
HMS2051K14
HMS2090M20
Hyphanox
I01-1043
I0732
ITC
ITCZ
ITZ
Intraconazole
 
Itraconazol
Itraconazol [Spanish]
Itraconazole
Itraconazole & Bovine Lactoferrin
Itraconazole & Nyotran
Itraconazole & Nyotran(Liposomal Nystatin)
Itraconazole (JAN/USAN)
Itraconazole [USAN:BAN:INN:JAN]
Itraconazole oral solution
Itraconazolum
Itraconazolum [Latin]
Itrizole
Itrizole (TN)
Itrizole (tn)
LS-1843
MLS000028582
MLS000759472
MLS000863291
MLS001148245
MolPort-000-883-864
MolPort-003-848-295
NCGC00089812-03
Oriconazole
Oriconazole, R51211, Sporanox
Orungal
Prokanazol
R 51211
R-51211
S2476_Selleck
SAM001246679
SMR000058959
Sempera
Spherazole
Sporal
Sporanos
Sporanox
Sporanox (TN)
Sporanox (tn)
Sporonox
TL8005525
Triasporn
UNII-304NUG5GF4
cis-Itraconazole
itraconazole
20
MiconazolePhase 4, Phase 3, Phase 2, Phase 1357322916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
21
AlendronatePhase 4, Phase 3157121268-17-5, 66376-36-12088
Synonyms:
(4-Amino-1-hydroxybutylidene)bisphosphonic acid
(4-Amino-1-hydroxybutylidene)diphosphonic acid
(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid
(4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid)
(4-amino-1-hydroxybutylidene)bisphosphonic acid
121268-17-5 (mono-hydrochloride salt, trihydrate)
1yhm
4-Amino-1-hydroxybutane-1,1-diphosphonate
4-Amino-1-hydroxybutane-1,1-diphosphonic Acid
4-Amino-1-hydroxybutylidene-1,1-bis(phosphonic acid)
4-Amino-1-hydroxybutylidene-1,1-bisphosphonate
4-amino-1-hydroxybutane-1,1-diphosphonic acid
66376-36-1
ABDP
AC1L1CW3
AKOS001015793
ALENDRONATE SODIUM
ALENDRONIC ACID
Acide Alendronique
Acide Alendronique [INN-French]
Acide alendronique
Acide alendronique [INN-French]
Acido Alendronico
Acido Alendronico [INN-Spanish]
Acido alendronico
Acido alendronico [INN-Spanish]
Acidum Alendronicum
Acidum Alendronicum [INN-Latin]
Acidum alendronicum
Acidum alendronicum [INN-Latin]
Adronat
 
Alendronate
Alendronate Sodium
Alendronate sodium hydrate
Alendronic acid
Alendronic acid (INN)
Alendronic acid [INN:BAN]
Alendros
Arendal
BIDD:GT0180
C07752
CHEBI:2567
CHEMBL870
CID2088
D07119
DB00630
Fosamax
Fosamax Plus D
HSCI1_000337
LS-106421
MK 217
MK-217
MolPort-000-421-410
NCGC00096054-01
NCGC00096054-03
NCGC00096054-04
Onclast
Oprea1_422906
Phosphonic acid, (4-amino-1-hydroxybutylidene)bis
SPECTRUM1505166
ST50036159
UNII-X1J18R4W8P
alendronate
bisphosphonate, 65
22hydroxyitraconazolePhase 4, Phase 2, Phase 1145
23
TobramycinPhase 4, Phase 3, Phase 2, Phase 111632986-56-45496, 36294
Synonyms:
1-Epitobramycin
11098-01-4
11111-45-8
3'-Deoxykanamycin B
3'-Deoxykanamycin b
32986-56-4
34337-51-4
37321-13-4
49842-07-1 (Sulfate)
54330-95-9
70322-33-7
79645-27-5
A 12253A
AB00513858
AC1L1KGY
AC1L1VI0
AC1O7GFJ
AC1Q2AOW
AKOS000715235
Aktob
BAS 00463364
BIDD:GT0503
BPBio1_000647
BRN 1357507
BSPBio_000587
BSPBio_002036
Brulamycin
C00397
C18H37N5O9
CAS-32986-56-4
CHEBI:28864
CHEBI:533587
CHEMBL1747
CID11340303
CID36294
CID5496
CID6604388
CID9804613
CID9934285
CPD000058793
D00063
DB00684
Deoxykanamycin B
Distobram
EINECS 251-322-5
Gotabiotic
HMS1569N09
HMS2090B16
HMS2092M17
HSDB 3259
KBio2_001552
KBio2_004120
KBio2_006688
KBio3_001536
KBioGR_001104
KBioSS_001552
LS-146940
LS-187329
Lilly 47663
MLS000069544
MolPort-001-934-131
MolPort-003-665-548
MolPort-003-939-629
NCGC00016814-01
NCGC00178852-01
NCGC00178852-02
NEBRAMYCIN
NF 6
NSC 180514
 
NSC180514
Nebcin
Nebcin (Sulfate)
Nebicin
Nebramycin 6
Nebramycin VI
Nebramycin factir 6
Nebramycin factor 6
Nebramycin-Faktor 6
O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamine
Obracin
Obramycin
Prestwick0_000544
Prestwick1_000544
Prestwick2_000544
Prestwick3_000544
Prestwick_850
S2514_Selleck
SAM001246911
SMR000058793
SPBio_000295
SPBio_002508
SPECTRUM1500579
SPRC-AB01
STK182610
Spectrum2_000078
Spectrum3_000588
Spectrum4_000752
Spectrum5_001038
Spectrum_001072
Sybryx
T4014_SIGMA
TOA-(1-6)2TB-(4-1)TOC
TOA-(1-6)TOB-(4-1)TOC
TOBRAMYCIN SULFATE
TOY
Tenebrimycin
Tenemycin
Tobacin
Tobi
Tobracin
Tobracin (TN)
Tobracin (tn)
Tobradex
Tobradistin
Tobralex
Tobramaxin
Tobramicin
Tobramicina
Tobramicina [INN-Spanish]
Tobramitsetin
Tobramycetin
Tobramycin
Tobramycin (JP15/USP)
Tobramycin Sulfate
Tobramycin [USAN:BAN:INN:JAN]
Tobramycin for Inhalation
Tobramycin solution for inhalation
Tobramycin, Free Base
Tobramycine
Tobramycine [INN-French]
Tobramycinum
Tobramycinum [INN-Latin]
Tobrased
Tobrasone
Tobrex
Tobrex (TN)
Tobrex (tn)
UNII-VZ8RRZ51VK
tobramycin
tobramycin solution for inhalation
24
PiperacillinPhase 49066258-76-243672
Synonyms:
(2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S-(2alpha,5alpha,6beta(S*)))-6-(((((4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl)amino)phenylacetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
4-ethyl-2,3-dioxopiperazine carbonyl ampicillin
59703-84-3
59703-84-3 (mono-hydrochloride salt)
6-(D-(-)-alpha-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)phenylacetamido)penicillanic acid
61477-96-1
6beta-{(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylic acid
AC1L2ACR
AC1Q5QXJ
BIDD:GT0167
BPBio1_000848
BRD-K86873305-236-03-0
BSPBio_000770
C14034
C23H27N5O7S
CCRIS 7362
CHEBI:8232
CHEMBL702
CID43672
Cl-227193
D08380
EINECS 262-811-8
HMS2090H19
LS-149794
 
PIPC
PIPERACILLIN SODIUM
Peperacillin
Peracin
Peracin (TN)
Piperacilina
Piperacillin
Piperacillin (INN)
Piperacillin (anhydrous)
Piperacillin Anhydrous
Piperacillin Monosodium Salt
Piperacillin anhydrous
Piperacillina
Piperacillinum
Pipercillin
Pipracil
Pipracil, Piper
Pipril
Pipéracilline
Prestwick0_000755
Prestwick1_000755
Prestwick2_000755
Prestwick3_000755
SPBio_002709
T-1220
UNII-9I628532GX
piperacillin
25
TazobactamPhase 49289786-04-9123630
Synonyms:
(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4
(2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
89785-84-2
89786-04-9
AC-7620
AC1L3X07
BIDD:GT0212
C07771
CHEBI:100207
CHEMBL404
 
CID123630
CL-298741
CL298741
D00660
DB01606
MolPort-002-500-123
TAZ
Tazobactam
Tazobactam (JAN/USAN/INN)
YTR-830H
YTR830H
26
AltretaminePhase 458645-05-62123
Synonyms:
2,4, 6-Tris(dimethylamino)-1,3,5-triazine
2,4,6-Tris(dimethylami
2,4,6-Tris(dimethylamino)-1,3,5-triazine
2,4,6-Tris(dimethylamino)-S-triazine
2,4,6-Tris(dimethylamino)-s-triazine
2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine
549835_ALDRICH
645-05-6
A 8723
A0567/0026158
A8723_SIGMA
AB00052308
AC-12006
AC1L1CYX
AI3-50852
AKOS001729401
Altretamin
Altretamina
Altretamina [INN-Spanish]
Altretamine (USP/INN)
Altretamine Bellon Brand
Altretamine Chiesi Brand
Altretamine Wassermann Brand
Altretamine [USAN:INN:BAN]
Altretaminum
Altretaminum [INN-Latin]
Altrétamine
BPBio1_001004
BRD-K67043667-001-04-1
BRN 0195058
BSPBio_000912
Bellon Brand of Altretamine
C9H18N6
CAS-654-05-6
CCRIS 5492
CHEBI:24564
CHEMBL1455
CID2123
CPD000058181
ChemDiv2_005185
Chiesi Brand of Altretamine
D006585
D02841
DB00488
DivK1c_000772
EINECS 211-428-4
ENT 50852
EU-0100083
FT-0083576
HEXAMETHYLMELAMINE
HMM
HMS1383L15
HMS1570N14
HMS1922C05
HMS2090G17
HMS2092H16
HMS502G14
HSDB 7559
HTM
HXM
Hemel
Hexalen
Hexalen (TN)
Hexalen, Altretamine
 
Hexamethylmelamine
Hexastat
Hexinawas
I06-0604
IDI1_000772
IDI1_003900
InChI=1/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H
KB-913
KBio1_000772
KBio2_001788
KBio2_004356
KBio2_006924
KBio3_002042
KBioGR_001388
KBioSS_001788
LS-1549
Lopac-A-8723
Lopac0_000083
MGI Pharma Brand of Altretamine
MLS000069621
MLS001076123
MolPort-002-111-210
N,N,N',N',N'',N''-hexamethyl-1,3,5-triazine-2,4,6-triamine
NC 195
NCGC00015100-01
NCGC00015100-02
NCGC00015100-03
NCGC00015100-06
NCGC00015100-11
NCGC00021216-03
NCGC00021216-04
NCGC00021216-05
NCGC00021216-06
NCGC00021216-07
NCI-C50259
NCI60_000871
NINDS_000772
NSC 13875
NSC-13875
NSC13875
N~2~,N~2~,N~4~,N~4~,N~6~,N~6~-Hexamethyl-1,3,5-triazine-2,4,6-triamine
Prestwick0_000946
Prestwick1_000946
Prestwick2_000946
Prestwick3_000946
Rhone Poulenc Rorer Brand of Altretamine
Rhone-Poulenc Rorer Brand of Altretamine
S1278_Selleck
SAM002564241
SMR000058181
SPBio_000754
SPBio_003071
SPECTRUM1503065
ST086739
STK749184
Spectrum2_000907
Spectrum3_000951
Spectrum4_001064
Spectrum5_001092
Spectrum_001308
UNII-Q8BIH59O7H
WLN: T6N CN ENJ BN1&1 DN1&1 FN1&1
Wassermann Brand of Altretamine
ZINC00000905
altretamine
no)-s-triazine
27
Mycophenolic acidPhase 4, Phase 391924280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
28
CiprofloxacinPhase 4, Phase 2, Phase 122185721-33-12764
Synonyms:
1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
1-CYCLOPROPYL-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperzinyl)-3-quinolinecarboxylic acid HCl H2O
1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinoline carboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
17850_FLUKA
3-Quinolinecarboxylic acid,1,4-dihydro-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)
33434_FLUKA
33434_RIEDEL
85721-33-1
AC-7613
AC1L1EEW
AKOS000269653
ARONIS020379
Alcon Cilox
BAS 06989041
BAY q 3939
BAY-Q-3939
BAYQ3939
BIDD:GT0205
BPBio1_000140
BRD-K04804440-311-02-3
BRN 3568352
BSPBio_000126
BSPBio_003344
Bacquinor
Baflox
Bay o 9867
Bay o 9867 (*Hydrochloride*)
Bay-09867
Baycip
Bernoflox
Bi-Cipro
Bio-0540
C05349
C17H18FN3O3
CAS-93107-08-5
CBMicro_048498
CCRIS 5241
CHEBI:100241
CHEMBL8
CID2764
CIPRO IN DEXTROSE 5% IN PLASTIC CONTAINER
CIPRO IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
CPF
CPFX
CRL-1605 & Ciprofloxacin
Ciflox
Cifloxin
Cilab
Ciloxan
Ciloxan (*Hydrochloride*)
Ciplus
Ciprecu
Ciprinol
Cipro
Cipro (*Hydrochloride*)
Cipro (TN)
Cipro I.V.
Cipro IV
Cipro XL
Cipro XR
Ciprobay
Ciprobay Uro
Ciprocinol
Ciprodar
Ciproflox
Ciprofloxacin
Ciprofloxacin (JAN/USP/INN)
Ciprofloxacin HCl
Ciprofloxacin Hydrchloride
Ciprofloxacin [USAN:INN:BAN]
Ciprofloxacin dihydrochloride
Ciprofloxacin hydrochloride
Ciprofloxacin monohydrochloride
Ciprofloxacina
Ciprofloxacine
Ciprofloxacine [INN-French]
Ciprofloxacino
 
Ciprofloxacino [INN-Spanish]
Ciprofloxacinum
Ciprofloxacinum [INN-Latin]
Ciprogis
Ciprolin
Ciprolon
Cipromycin
Ciproquinol
Ciprowin
Ciproxan
Ciproxin
Ciproxina
Ciproxine
Ciriax
Citopcin
Cixan
Corsacin
Cycin
Cyprobay
D00186
DB00537
DivK1c_000095
Eni
Fimoflox
Flociprin
Floxin
HMS1922E18
HMS2090O07
HMS2093I03
HMS500E17
HSDB 6987
IDI1_000095
Ipiflox
Italnik
KBio1_000095
KBio2_000642
KBio2_003210
KBio2_005778
KBio3_002846
KBioGR_001567
KBioSS_000642
LS-141563
Liposomal-ciprofloxacin
Loxan
MLS001336035
MolPort-000-819-654
NCGC00016959-01
NCGC00095058-01
NCGC00095058-02
NCGC00178128-01
NINDS_000095
NSC620634
Ocuflox
Oprea1_008239
Oprea1_313572
Prestwick0_000113
Prestwick1_000113
Prestwick2_000113
Prestwick3_000113
Probiox
Proflaxin
Proflox
Proksi 250
Proksi 500
Proquin XR
Quinolid
Quintor
Rancif
Roxytal
SMP1_000125
SMR000471901
SPBio_001474
SPBio_002065
SPECTRUM1503614
STK021082
Septicide
Sophixin Ofteno
Spectrum2_001567
Spectrum3_001872
Spectrum4_000874
Spectrum5_001089
Spectrum_000162
Spitacin
Superocin
UNII-5E8K9I0O4U
Unex
Velomonit
Zumaflox
ciprofloxacin
nchembio820-comp1
29
ColistinPhase 4, Phase 2, Phase 1591264-72-8, 1066-17-75311054
Synonyms:
1066-17-7
AC1NSJWT
CID5311054
Colistin
Colistin sulfate, nonsterile
Colistin sulphate
 
Colistina
Colistine
Colistinum
DB00803
N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-5-methylheptanamide
Polymyxin E
Polymyxin E. Sulfate
colistin
30
AzithromycinPhase 4, Phase 3, Phase 2, Phase 133083905-01-555185, 53477736, 447043
Synonyms:
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one
1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*
121470-24-4
75199_FLUKA
83905-01-5
9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A
AC-16014
AC1L9KEG
Aritromicina
Azasite
Azenil
Azifast
Azigram
Azimakrol
Azithramycine
Azithromycin
Azithromycin & Tumor Necrosis Factor
Azithromycin (AIDS Initiative)
Azithromycin (anhydrous)
Azithromycin Dihydrate
Azithromycin Monohydrate
Azithromycin Sterile
Azithromycin dihydrate
Azithromycin plus Tumor Necrosis Factor
Azithromycine
Azithromycine [French]
Azithromycinum
Azithromycinum [Latin]
Azitrocin
Azitromax
Azitromicina
Azitromicina [Spanish]
Azitromin
Azythromycin
BIDD:GT0792
BRN 5387583
BSPBio_002285
Bio-0676
C38H72N2O12
CCRIS 1961
CHEBI:2955
CHEMBL529
CID447043
CP-62993
CP62,993
CPD000471864
DCH3
DRG-0104
 
DivK1c_000233
HMS1922G12
HMS2094M11
HMS500L15
HSDB 7205
Hemomycin
IDI1_000233
KBio1_000233
KBio2_000787
KBio2_003355
KBio2_005923
KBio3_001505
KBioGR_000731
KBioSS_000787
LS-1834
MLS001055353
MLS001066331
MLS001201763
MLS001304005
MLS001332499
MLS001332500
Misultina
MolPort-002-507-426
N,N-Dimethyl-4-amino-benzaldehyde
NCGC00090753-01
NCGC00090753-02
NINDS_000233
NSC643732
SAM002589961
SMR000471864
SPBio_001544
SPECTRUM1503679
Spectrum2_001582
Spectrum3_000653
Spectrum4_000186
Spectrum5_001867
Spectrum_000307
Sumamed
Tromix
UNII-JTE4MNN1MD
XZ-450
Z-Pak
ZIT
Zentavion
Zithromac
Zithromax
Zithromax IV
Zithromycin
Zitromax
Zitromax Avium 600
Zmas
Zmax
azithromycin
31
PancrelipasePhase 4, Phase 3, Phase 291753608-75-6
Synonyms:
1,4-alpha-D- glucan glucanohydrolase
PA
 
Pancreatic alpha-amylase precursor
Pancrelipase (amylase
lipase
protease)
32pancreatinPhase 4, Phase 3, Phase 2917
33
Mycophenolate mofetilPhase 4, Phase 3919128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
34vitamin dPhase 4, Phase 3, Phase 1, Phase 21607
35
MeropenemPhase 485119478-56-764778, 441130
Synonyms:
(1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate
(1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid
(2S,3R,4R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid
(4R,5S,6S)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5S,6S)-3-((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-ylthio)-6-((S)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid
96036-03-2
AB00514051
AB1004614
AC1L9ALL
Ambap119478-56-7
Antibiotic SM 7338
Antibiotic sm 7338
BIDD:GT0851
BPBio1_001334
BSPBio_001212
CHEBI:43968
CHEMBL127
CID441130
CPD000469184
D08185
HMS1571M14
HMS2051G08
HMS2090C05
 
ICI-194660
MEPM
MERONEM
MLS001401437
Meronem (TN)
Meropen
Meropenem
Meropenem (INN)
Meropenem Hydrate
Meropenem anhydrous
Meropenem trihydrate
Meropenemum
Meropenemum [INN-Latin]
Meropenemum trihydricum
Merrem
Merrem I.V. (TN)
MolPort-006-709-417
NCGC00179259-01
Prestwick0_001106
Prestwick1_001106
Prestwick2_001106
Prestwick3_001106
SAM001246650
SM-7338
SMR000469184
SPBio_003086
36
ProcaterolPhase 43172332-33-3688561
Synonyms:
(R*,S*)-(+-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone
5-[1-hydroxy-2-(propan-2-ylamino)butyl]quinoline-2,8-diol
60443-17-6
62929-91-3 (mono-hydrochloride)
72332-33-3
8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone
8-hydroxy-5-[1-hydroxy-2-(propan-2-ylamino)butyl]-1H-quinolin-2-one
AC-13705
AC1L1J8G
AC1Q6I3X
AR-1J3938
BRD-A22684332-003-02-3
BSPBio_003239
CHEMBL160519
CI-888
CID4916
D08424
EINECS 276-590-0
KBio3_002739
L023776
 
LS-142797
Meptin
Meptin (TN)
MolPort-005-934-511
NSC 308904
NSC308904
OPC-2009
PROCATEROL
Pro-Air
Procaterol (INN)
Procaterol Monohydrochloride
Procaterol [INN:BAN]
Procaterolo
Procaterolo [DCIT]
Procaterolum
Procaterolum [INN-Latin]
Procaterolum [Latin]
SPBio_001400
STK632659
Spectrum2_001550
Spectrum3_001770
37
CefepimePhase 43588040-23-75479537
Synonyms:
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
1-(((6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-1-methylpyrrolidinium hydroxide, inner salt, 7(sup 2)-(Z)-(O-methyloxime)
7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methylpyrrolidinium-1-yl)methyl]-3,4-didehydrocepham-4-carboxylate
88040-23-7
AC1NUIFH
Axepim
BMY 28142
BMY-28142
C08111
C19H24N6O5S2
CFPM
CHEBI:478164
CHEMBL186
CID5479537
Cefepima
Cefepima [Spanish]
 
Cefepima [spanish]
Cefepime
Cefepime (USAN/INN)
Cefepime [USAN:INN]
Cefepimum
Cefepimum [Latin]
Cefepimum [latin]
Cepimax
Cepimex
D02376
DB01413
HMS2089M18
LS-178033
Maxcef
Maxipime
UNII-807PW4VQE3
ZINC03871924
cefepime
38AvibactamPhase 4261192500-31-4
39
PosaconazolePhase 452171228-49-2147912
Synonyms:
1-((1S,2S)-1-Ethyl-2-hydroxypropyl)-4-{4-[4-(4-{[(5S,3R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazolylmethyl)oxolan-3-yl]methoxy}phenyl)piperazinyl]phenyl}-1,2,4-triazolin-5-one
171228-49-2
177571-33-4
4-(p-(4-(p-(((3R,5R)-5-(2,4-Difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furyl)methoxy)phenyl)-1-piperazinyl)phenyl)-1-((1S,2S)-1-ethyl-2-hydroxypropyl)-delta(sup 2)-1,2,4-triazolin-5-one
4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one
4-[4-[4-[4-[[(5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one
AC-1350
AC1L3W34
AC1LAHLQ
AKOS005145917
CHEBI:434337
CHEMBL1397
CHEMBL371938
CHEMBL371939
CID10532764
CID11520437
CID11542142
CID147912
CID468595
D02555
 
DB01263
HSDB 7421
LS-186118
LS-186988
LS-187630
MolPort-006-666-426
Noxafil
Noxafil (TN)
Noxafil, Posaconazole
Posaconazole
Posaconazole (USAN/INN)
Posaconazole SP
Posaconazole [USAN:INN:BAN]
Posaconazole in combination with MGCD290
S1257_Selleck
SCH-56592
SCH56592
Sch 56592
Spriafil
UNII-6TK1G07BHZ
X2N
posaconazole
40
OmalizumabPhase 4139242138-07-4
Synonyms:
242138-07-4
D05251
Ig gamma-1 chain C region
Omalizumab
 
Omalizumab (USAN/INN)
Omalizumab (genetical recombination)
Omalizumab (genetical recombination) (JAN)
Xolair
Xolair (TN)
41
TacrolimusPhase 41058104987-11-3445643, 439492
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
Anhydrous tacrolimus
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
 
FR900506
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus anhydrous
Tacrolimus hydrate
Tacrolimus, anhydrous
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
42
CholecalciferolNutraceuticalPhase 4, Phase 3, Phase 1, Phase 282667-97-06221, 10883523, 5280795
Synonyms:
()-Vitamin D3
(+)-Vitamin D3
(+)-vitamin D3
(1S,3Z)-3-[(2e)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol
(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7e)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol
(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(5Z,7e)-(3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
1406-16-2
25(OH)D
3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol
47763_SUPELCO
57651-82-8
67-97-0
7-Dehydrocholesterol activated
7-Dehydrocholesterol, Activated
7-Dehydrocholesterol, irradiated
7-Dehydrocholestrol, activated
8024-19-9
8050-67-7
89193_FLUKA
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol
9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol
9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol
9,10-Secocholesta-5,7,10(19)-trien-3-ol
9,10-Secocholesta-5,7,10-trien-3-ol
AB1002422
AC-11697
AC1L1ECK
AC1L1M23
AC1LU7IZ
AC1NQXLN
AC1NR2UO
AC1NR2UR
AC1NR2UU
AC1NS4AJ
AC1NSHJX
AC1O5EOF
AC1O7GAV
AC1O7GQ3
AC1O8FEU
AC1O8PWJ
AC1OF2GI
AC1OF2GL
AC1OIEW5
AC1OIEWB
ACon1_001997
Activated 7-dehydrocholesterol
Arachitol
BPBio1_000460
BSPBio_000418
BSPBio_002408
Bio-0845
C05443
C1357_SIAL
C27H44O
C9756_SIGMA
C9774_SIAL
CAS-67-97-0
CC
CCRIS 5813
CCRIS 6286
CHEBI:283119
CHEBI:28940
CHEMBL1042
CHEMBL432780
CID10000117
CID10045875
CID10340013
CID10883523
CID10894379
CID11014566
CID11025493
CID11058152
CID11463269
CID1548921
CID2735
CID5280795
CID5283710
CID5283711
CID5283712
CID5353527
CID5363362
CID6221
CID6432644
CID6604201
CID6604662
CID6708595
CID6713938
CID6992015
CID6992016
CID7067439
CID7067440
CID7251172
CID7251174
CID9821465
Calciol
Cholecalciferol
Cholecalciferol (D3)
Cholecalciferol (JP15/USP)
Cholecalciferol D3
Cholecalciferol [USAN:BAN:JAN]
Cholecalciferol, D3
Cholecalciferolum
 
Colecalciferol
Colecalciferol (INN)
Colecalciferolo
Colecalciferolo [DCIT]
Colecalciferolum
Colecalciferolum [INN-Latin]
Colecalcipherol
D00188
D3-Vicotrat
D3-Vigantol
DB00169
Delsterol
Delta-D
Delta-D (TN)
Deparal
Devaron
DivK1c_006276
Duphafral D3 1000
EINECS 200-673-2
EINECS 215-797-2
EPA Pesticide Chemical Code 202901
Ebivit
FeraCol
Granuvit D3
HMS1569E20
HMS2092M12
HSDB 820
I05-0041
Irradiated 7-dehydrocholesterol
KBio1_001220
KBio2_001643
KBio2_004211
KBio2_006779
KBio3_001628
KBioGR_001602
KBioSS_001643
LMST03020001
LMST03020219
LMST03020220
LMST03020221
LS-1570
LS-825
LT00244775
MEGxm0_000458
Micro-dee
MolPort-001-740-051
MolPort-001-785-972
MolPort-003-666-021
MolPort-004-946-964
NCGC00016301-01
NCGC00017328-01
NCGC00091072-01
NCGC00142511-01
NCGC00159331-02
NCGC00159331-04
NCGC00178668-01
NCGC00179565-01
NCGC00179565-02
NEO Dohyfral D3
NSC 375571
NSC-375571
NSC375571
Oleovitamin D3
Prestwick0_000429
Prestwick1_000429
Prestwick2_000429
Prestwick3_000429
Prestwick_63
Provitamine
Provitina
Quintox
Rampage
Ricketon
SMP1_000068
SPBio_001298
SPBio_002357
SR-05000001559
SR-05000001559-3
ST057172
SpecPlus_000180
Spectrum2_001369
Spectrum3_000764
Spectrum4_001201
Spectrum_001163
TNP00266
Trivitan
UNII-1C6V77QF41
UPCMLD-DP152
UPCMLD-DP152:001
VITAMIN D
VITAMIN D3 POWDER
VITAMIN_D3
Vi-De3
Vi-de-3-hydrosol
VidDe-3-hydrosol
Videkhol
Vigantol
Vigorsan
Vitamin D3
Vitamin D3 emulsifiable
Vitinc Dan-Dee-3
ZINC04474460
ZINC04492874
ZINC04492875
ZINC04492876
ZINC04492878
bmse000507
calciol
cholecalciferol
delta-D
vitamin d-3
43serineNutraceuticalPhase 4, Phase 2, Phase 1883
44cysteineNutraceuticalPhase 4, Phase 1, Phase 2166
45
ErgocalciferolNutraceuticalPhase 4, Phase 3, Phase 1, Phase 2121150-14-65280793
Synonyms:
'Ergosterol irradiated'
(+)-Vitamin D2
(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol
31316-19-5
4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol
47768_SUPELCO
50-14-6
7489-18-1
7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87
8017-28-5
9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol
9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol
95220_FLUKA
95220_SIGMA
AC-1355
AC1L1FIE
AC1NQXLH
AC1NS4DE
AC1NS9GI
AC1NSSVD
AC1NWAM3
AC1O5EDK
AC1O6WAM
ACon1_002187
Activated ergosterol
BPBio1_000418
BSPBio_000380
BSPBio_001974
Buco-D
C05441
C28H44O
CALCIFEROL IN A GELATIN MATRIX
CALCIFEROL, U.S.P.
CHEBI:28934
CHEMBL1536
CID11003810
CID3249
CID5280793
CID5315257
CID5353610
CID5356615
CID5702050
CID6432478
CID6536972
Calciferol
Calciferol (TN)
Calciferol (vitamin D2)
Calciferolum
Calciferon 2
Condacaps
Condocaps
Condol
Crtron
Crystallina
D-Arthin
D-Tracetten
D00187
DB00153
Daral
Davitamon D
Davitin
De-rat concentrate
Decaps
Dee-Osterol
Dee-Ron
Dee-Ronal
Dee-Roual
Deltalin
Deratol
Detalup
Diactol
Divit urto
Doral
Drisdol
Drisdol (TN)
E5750_SIGMA
EINECS 200-014-9
Ercalciol
Ergocalciferol
Ergocalciferol (D2)
Ergocalciferol (JP15/USP)
Ergocalciferol [INN:BAN:JAN]
Ergocalciferol oil
Ergocalciferol: Vitamin D
 
Ergocalciferolo
Ergocalciferolo [DCIT]
Ergocalciferols
Ergocalciferolum
Ergocalciferolum [INN-Latin]
Ergorone
Ergosterol activated
Ergosterol irradiated
Ergosterol, irradiated
Ertron
Fortodyl
Geltabs
Geltabs Vitamin D
HMS1920K20
HMS2091B19
HMS502I07
HSDB 819
Haliver
Hi-Deratol
Hyperkil
I05-0022
IDI1_000805
Infron
Irradiated ergosta-5,7,22-trien-3-beta-ol
Irradiated ergosta-5,7,22-trien-3.beta.-ol
Irradiated ergosta-5,7,22-trien-3beta-ol
Irradiated ergosterol
LMST03010001
LMST03010014
LS-3228
MEGxm0_000466
MLS001332467
MLS001332468
Metadee
Mina D2
MolPort-001-740-057
MolPort-001-793-930
MolPort-002-526-645
MolPort-003-666-178
MolPort-006-822-629
Mulsiferol
Mykostin
NCGC00142497-01
NCGC00179579-01
NCGC00179579-02
NSC 62792
NSC62792
Novovitamin-D
Oleovitamin D
Oleovitamin D, Synthetic
Oleovitamin D2
Osteil
Ostelin
Prestwick3_000420
Prestwick_554
Radiostol
Radstein
Radsterin
Rodine C
Rodinec
SMR000857106
SPECTRUM1500276
ST057150
STOCK1N-53397
Shock-ferol
Shock-ferol sterogyl
Sorex C.R
Sorex C.R.
Spectrum5_000666
Sterogyl
Synthetic Vitamin D
UNII-VS041H42XC
Uvesterol D
Uvesterol-D
VITAMIN D2
VITAMIN D2 WATER DISPERSABLE U.S.P.
VITAMIN_D2
Vigantol
Vio D
Vio-D
Viostdrol
Viosterol
Viosterol in Oil
Vitamin D2
Vitamin- D2
Vitamin-?D2
Vitamina D2
Vitavel-D
WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ
ZINC04474571
ZINC04629876
beta-Ol
bmse000510
component of Geltabs Vitamin D
delta-Arthin
delta-Tracetten
ergocalciferol
vitamin d-2
46ACIDOPHILUSNutraceuticalPhase 4, Phase 3502
47
OfloxacinPhase 3, Phase 2, Phase 121582419-36-14583
Synonyms:
( -)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazin-6-carbonsaeure
(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperaz inyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7- -oxo-7H-pyrido(1,2,3-de)- -1,4-benzoxazine-6-carboxylic acid
(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
(+/-)-Floxin
118120-51-7 (hydrochloride)
33703_FLUKA
33703_RIEDEL
8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
82419-36-1
83380-47-6
85344-55-4
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
AB00513820
AC-7616
AC1L1IHM
AKOS001033517
BB_SC-1252
BPBio1_000345
BRD-A24228527-001-05-9
BRN 3657947
BSPBio_000313
BSPBio_003117
Bactocin
C07321
C18H20FN3O4
CCRIS 5233
CHEBI:7731
CHEMBL4
CID4583
CPD000058192
D00453
DB01165
DEXTROFLOXACINE
DL 8280
DL-8280
DL-8280, HOE-280, Exocin, Flobacin, Floxin, Floxil, Monoflocet, Ofloxacin
Danoflox
DivK1c_000721
EU-0100904
Effexin
Exocin
Exocine
FLOXIN IN DEXTROSE 5%
FLOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER
Flobacin
Flodemex
Flotavid
Flovid
Floxal
Floxil
Floxin
Floxin (TN)
Floxin otic
Floxstat
Fugacin
HMS1568P15
HMS1921H12
HMS2090F07
HMS2092B10
HMS502E03
HOE 280
Hoe-280
I06-0112
I06-0380
IDI1_000721
Inoflox
KBio1_000721
KBio2_001666
KBio2_004234
KBio2_006802
KBio3_002617
KBioGR_000667
KBioSS_001666
Kinflocin
Kinoxacin
LS-133259
Liflox
Lopac0_000904
Loxinter
MLS000028749
MLS001074203
Marfloxacin
Medofloxine
Mergexin
MolPort-000-422-241
MolPort-000-873-068
NCGC00015772-02
NCGC00015772-10
 
NCGC00094219-01
NCGC00094219-02
NCGC00094219-03
NCGC00094219-04
NCGC00094219-05
NCGC00094219-06
NCGC00178284-01
NCGC00178284-02
NINDS_000721
NSC727071
Novecin
Nufafloqo
O 8757
O-Flox
O8757_SIGMA
OFLX
OFX
ORF 18489
ORF-28489
Obide
Occidal
Ocuflox
Ofcin
Oflin
Oflocee
Oflocet
Oflocin
Oflodal
Oflodex
Oflodura
Oflox
Ofloxacin (JP15/USP/INN)
Ofloxacin Otic
Ofloxacin [USAN:BAN:INN:JAN]
Ofloxacin, (S)-Isomer
Ofloxacina
Ofloxacina [DCIT]
Ofloxacine
Ofloxacine [French]
Ofloxacino
Ofloxacino [Spanish]
Ofloxacinum
Ofloxacinum [Latin]
Ofloxin
Ofus
Onexacin
Operan
Oprea1_242882
Orocin
Otonil
Oxaldin
PT 01
Pharflox
Praxin
Prestwick0_000237
Prestwick1_000237
Prestwick2_000237
Prestwick3_000237
Puiritol
Qinolon
Qipro
Quinolon
Quotavil
Rilox
Ru-43280
S1463_Selleck
SAM002264629
SMR000058192
SPBio_001387
SPBio_002234
SPECTRUM1502044
STK256723
Sinflo
Spectrum2_001464
Spectrum3_001499
Spectrum4_000324
Spectrum5_001063
Spectrum_001186
Tabrin
Taravid
Tariflox
Tarivid
Telbit
Tructum
UNII-A4P49JAZ9H
Uro Tarivid
Viotisone
Visiren
WP-0405
XED
Zanocin
ofloxacin
48
LevofloxacinPhase 3, Phase 2, Phase 1215100986-85-4149096
Synonyms:
(−
(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyridol[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate
(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7Hpyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate
(-)-Ofloxacin
(3S)-(-)-9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(R)-isomer
(S)-(-)-9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid
(S)-(-)-Ofloxacin
(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(S)-Ofloxacin
)-Ofloxacin
100986-85-4
100986-86-5
28266_FLUKA
28266_SIGMA
AC-7593
AC1L3YF8
Aeroquin
Ambap100986-85-4
BRD-K09471561-001-06-7
BSPBio_002689
C07660
C18H20FN3O4
C18H20FN3O4.H2O
CCRIS 4073
CCRIS 4074
CHEMBL33
CID149096
CPD000466387
Cravit
Cravit (TN)
Cravit Ophthalmic
D08120
DB01137
DR 3354
DR-3355
DR-3355: L-isomer of ofloxacin
DR3355
Elequine
Floxacin
Floxel
Floxin
HMS1922J07
HMS2051G04
HMS2090O10
HMS2093E18
HR 355
HR-355
Iquix
KBio2_002199
KBio2_004767
KBio2_007335
KBio3_001909
 
KBioGR_001605
KBioSS_002199
L-Ofloxacin
L-ofloxacin
L0193
LEVAQUIN IN DEXTROSE 5% IN PLASTIC CONTAINER
LEVOFLOXACIN
LFX
LS-133260
LS-171761
LVX
Leroxacin
Lesacin
Levaquin
Levofloxacin
Levofloxacin (INN)
Levofloxacin [USAN:INN:JAN]
Levofloxacin hydrate
Levofloxacin tablet, suspension or intravenous
Levofloxacine
Levofloxacine [INN-French]
Levofloxacino
Levofloxacino [INN-Spanish]
Levofloxacinum
Levofloxacinum [INN-Latin]
Levokacin
Levox
Levoxacin
MLS000759524
MLS001165709
MLS001423977
MP-376
MolPort-002-885-835
Mosardal
NCGC00178529-01
Nofaxin
Ofloxacin
Ofloxacin S-(-)-form
Oftaquix
Quixin
R-Ofloxacin
RWJ 25213-097
RWJ-25213
Reskuin
S-(-)-Ofloxacin
S1940_Selleck
SAM001246758
SMR000466387
SPBio_001891
SPECTRUM1504260
Spectrum2_001676
Spectrum3_000995
Spectrum4_001123
Spectrum5_001438
Spectrum_001719
Tavanic
Volequin
d-Levofloxacin
49
lactitolPhase 3325585-86-43871
Synonyms:
4-O-b-D-Galactopyranosyl-D-glucitol, 9CI
E966
Emportal
 
Floralac
Importal
Oponaf
Portolac
50
MiglustatPhase 2, Phase 32172599-27-051634
Synonyms:
(2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
1,5-Dideoxy-1,5-N-butylimino-D-glucitol
134282-77-2
72599-27-0
AC1L1BHJ
BuDNJ
Butyldeoxynojirimycin
CHEBI:49779
CHEBI:50381
CHEMBL1029
CID51634
D05032
DB00419
HMS2090N20
LS-116261
Miglustat
Miglustat (USAN/INN)
Miglustat [USAN]
Miglustat, Hydrochloride
Miglustatum
N-(N-Butyl)deoxynojirimycin
N-(n-Butyl)deoxynojirimycin
N-(n-butyl)-1,5-dideoxy-1,5-imino-D-glucitol
 
N-Bu-DNJ
N-Butyl deoxynojirimycin
N-Butyl-1-deoxynojirimycin
N-Butyl-DNJ
N-Butyl-deoxynojirimycin
N-Butyldeoxynojirimycin
N-Butylmoranoline
N-butyl-1-deoxynojirimycin
NB-DNJ
NB-dnj
NBV
OGT 918
OGT-918
SC 48334
SC-48334
SC48334
UNII-ADN3S497AZ
Vevesca
Zavesca
Zavesca (TN)
miglustatum
n-Butyl deoxynojirimycin
n-Butyl dnj
nchembio.81-comp12
nchembio850-comp5

Interventional clinical trials:

(show top 50)    (show all 900)
idNameStatusNCT IDPhase
1Cohort Study Evaluating the Clinical Effectiveness, Safety and Immunogenicity to the Pandemic Influenza VaccinationCompletedNCT01499914Phase 4
2Study of Alendronate to Prevent and Treat Osteoporosis in Cystic Fibrosis PatientsCompletedNCT00157690Phase 4
3Pharmacokinetics of Piperacillin, Given as Continuous Infusion to Patients With Cystic FibrosisCompletedNCT01983787Phase 4
4Tobramycin 300 mg Once-a-day (o.d.) Aerosol in Adults With Cystic FibrosisCompletedNCT01608555Phase 4
5Study of Long-term Treatment With Hypertonic Saline in Patients With Cystic FibrosisCompletedNCT01377792Phase 4
6Treatment of Aspergillus Fumigatus (a Fungal Infection) in Patients With Cystic FibrosisCompletedNCT00528190Phase 4
7Circadian Rhythm In Tobramycin Elimination In Cystic FibrosisCompletedNCT01207245Phase 4
8Comparison of Absorption of Vitamin D in Cystic FibrosisCompletedNCT01880346Phase 4
9The Effect of rhDNase on Ventilation Inhomogeneity in Patients With Cystic FibrosisCompletedNCT00557089Phase 4
10Should Any One Airway Clearance Technique be Recommended for People With Cystic Fibrosis?CompletedNCT00890370Phase 4
11Effect of Lactobacillus Reuteri in Cystic FibrosisCompletedNCT01737983Phase 4
12Population Pharmacokinetics of Prolonged Infusion Meropenem in Cystic Fibrosis (CF) ChildrenCompletedNCT01429259Phase 4
13Control of Steatorrhea in Participants With Cystic Fibrosis and Exocrine Pancreatic InsufficiencyCompletedNCT01327703Phase 4
14Comparison of 2 Treatment Regimens for Eradication of P Aeruginosa Infection in Children With Cystic FibrosisCompletedNCT01400750Phase 4
15Long Term Safety of Tobramycin Inhalation Powder in Patients With Cystic FibrosisCompletedNCT01519661Phase 4
16Effect of Azithromycin on Lung Function in 6-18 Year-olds With Cystic Fibrosis (CF) Not Infected With P. AeruginosaCompletedNCT00431964Phase 4
17Cystic Fibrosis and Totally Implantable Vascular Access DevicesCompletedNCT00244270Phase 4
18Scandinavian Cystic Fibrosis Azithromycin StudyCompletedNCT00411736Phase 4
19Comparison of Airway Clearance Therapy in Cystic Fibrosis Using the Same VEST Therapy Device But With Different SettingsCompletedNCT00685035Phase 4
20Doxycycline Effects on Inflammation in Cystic FibrosisCompletedNCT01323101Phase 4
21Eficacy of Long-term Suplementation With Docosahexaenoic Acid in Patients With Cystic FibrosisCompletedNCT01783613Phase 4
22A Study of the Comparable Efficacy and Safety of Pulmozyme (Dornase Alfa) Delivered by the eRapid Nebulizer System in Patients With Cystic FibrosisCompletedNCT01712334Phase 4
23Ease of Use and Microbial Contamination of Tobramycin Inhalation Powder (TIP) Versus Nebulised Tobramycin Inhalation Solution (TIS) and Nebulised Colistimethate (COLI)CompletedNCT01844778Phase 4
24One Year Glargine Treatment in CFRD Children and AdolescentsCompletedNCT00483769Phase 4
25A Study to Determine the Variability of a 6-Minute Walk Test in Cystic Fibrosis Subjects With Advanced Lung DiseaseCompletedNCT00311506Phase 4
26Study to Validate the Instructions for Use of TOBI® Podhaler™ in Cystic Fibrosis PatientsCompletedNCT02178540Phase 4
27A Study to Evaluate the Mode of Administration and Safety of EUR-1008 (APT-1008) in Infants 1 to 12 Months of AgeCompletedNCT01100606Phase 4
28PR-018: An Open-Label, Safety Extension of Study PR-011CompletedNCT01131507Phase 4
29Clinical Study With an Enteral Formula With Symbiotic and DHA for Malnourished ChildrenCompletedNCT02128984Phase 4
30Assessment of Response to Treatment of Osteoporosis With Oral Bisphosphonates in Patients With Muscular DystrophyCompletedNCT01882400Phase 4
31Malabsorption Blood Test:Toward a Novel Approach to Quantify SteatorrheaCompletedNCT00572975Phase 4
32Electro Flo 5000 and Vest TherapyCompletedNCT02277626Phase 4
33Effects of Tamoxifen in Premenopausal Women With Benign Breast Disease Not at High-Risk of Developing Breast CancerCompletedNCT00999921Phase 4
34Ext. Long-term Safety Study in CF Patients: Single Arm TIPCompletedNCT01775137Phase 4
35Effectiveness and Safety of Inhaling Hypertonic Saline in Patients With Chronic Obstructive Pulmonary DiseaseCompletedNCT00639236Phase 4
36Impact of Immunonutrition on the Patients With Cystic FibrosisRecruitingNCT02048592Phase 4
37Backpack Carrying in Children With Cystic FibrosisRecruitingNCT02700282Phase 4
38Population Pharmacokinetics and Safety of Intravenous Ceftolozane/Tazobactam in Adult Cystic Fibrosis PatientsRecruitingNCT02421120Phase 4
39Lung Disease and Its Affect on the Work of White Blood Cells in the LungsRecruitingNCT01851642Phase 4
40Evaluation of Lung Clearance Index in Cystic Fibrosis (CF) Patients, Infected With P.AeruginosaRecruitingNCT02248922Phase 4
41EASY: Extended Access to Sollpura Over YearsRecruitingNCT02823964Phase 4
42Testing the Effect of Adding Chronic Oral Azithromycin to Inhaled Tobramycin in People With CFRecruitingNCT02677701Phase 4
43Effects of a Partially Supervised Conditioning Program in CFRecruitingNCT01744561Phase 4
44A Pilot Study to Evaluate the Use of Smart Adherence Technology to Measure Medication Adherence in CF Subjects Who Are Homozygous for the F508del CFTR MutationRecruitingNCT02823470Phase 4
45IV Colistin for Pulmonary Exacerbations: Improving Safety and EfficacyRecruitingNCT02918409Phase 4
46Azithromycin for Children Hospitalized With AsthmaRecruitingNCT02003911Phase 4
47The Use of Oral N-Acetyl Cysteine for the Treatment of Chronic Sinonasal SymptomsRecruitingNCT00866866Phase 4
48A Study Comparing Continuous Infusion Antibiotics to Standard Treatment for Lung Infections in Cystic FibrosisActive, not recruitingNCT01667094Phase 4
49A Study to Confirm the Long-term Safety and Effectiveness of Kalydeco in Patients With Cystic Fibrosis Who Have an R117H-CFTR Mutation, Including Pediatric PatientsActive, not recruitingNCT02722057Phase 4
50CPET in CF Patients With One G551D Mutation Taking VX770Active, not recruitingNCT01937325Phase 4

Search NIH Clinical Center for Cystic Fibrosis

Inferred drug relations via UMLS66/NDF-RT44:

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Cystic Fibrosis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Cystic Fibrosis:
Mesenchymal stem cells for cystic fibrosis
Embryonic/Adult Cultured Cells Related to Cystic Fibrosis:
Mouse bone marrow-derived mesenchymal stem cells (family), PMIDs: 21658631, 20801416


Cochrane evidence based reviews: cystic fibrosis

Genetic Tests for Cystic Fibrosis

About this section

Genetic tests related to Cystic Fibrosis:

id Genetic test Affiliating Genes
1 Cystic Fibrosis25 23

Anatomical Context for Cystic Fibrosis

About this section

MalaCards organs/tissues related to Cystic Fibrosis:

34
Lung, Testes, Pancreas, Liver, Neutrophil, Colon, Bone

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Cystic Fibrosis:
id TissueAnatomical CompartmentCell Relevance
1 LungRespiratory BronchiolesBasal Cells Potential therapeutic candidate
2 LungRespiratory BronchiolesCilliated Cells Potential therapeutic candidate, affected by disease
3 LungSubmucosal Glands  Affected by disease

Animal Models for Cystic Fibrosis or affiliated genes

About this section

MGI Mouse Phenotypes related to Cystic Fibrosis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000538110.4CFTR, IFT122, SCNN1A, SCNN1B, SCNN1G, SLC9A3R1
2MP:000537610.3ABCC10, CFTR, CLCA1, DNASE1, ELANE, IFT122
3MP:001076810.0ABCC10, CFTR, DNASE1, ELANE, FCGR2A, IFT122

Publications for Cystic Fibrosis

About this section

Articles related to Cystic Fibrosis:

(show top 50)    (show all 3694)
idTitleAuthorsYear
1
High ambient temperature and risk of intestinal obstruction in cystic fibrosis. (27145507)
2016
2
Association of polymorphisms in genes of factors involved in regulation of splicing of cystic fibrosis transmembrane conductance regulator mRNA with acute respiratory distress syndrome in children with pneumonia. (27596159)
2016
3
Association between serum YKL-40 level and dysglycemia in cystic fibrosis. (25497736)
2015
4
Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity. (26079370)
2015
5
Preliminary study of haplotypes linked to the rare cystic fibrosis E1104X mutation. (25481366)
2015
6
674: IMPACT OF INFECTIOUS COMPLICATIONS ON OUTCOMES IN CHILDREN HOSPITALIZED DUE TO CYSTIC FIBROSIS. (26570335)
2015
7
Genotypes and phenotypes in cystic fibrosis and cystic fibrosis transmembrane regulator-related disorders. (25826586)
2015
8
Neonates with cystic fibrosis have a reduced nasal liquid pH; A small pilot study. (24418186)
2014
9
Analysis of cystic fibrosis gene mutations in children with cystic fibrosis and in 964 infertile couples within the region of Basilicata, Italy: a research study. (25304080)
2014
10
Short communication: novel truncating mutations in the CFTR gene causing a severe form of cystic fibrosis in Italian patients. (25501174)
2014
11
Conserved allosteric hot spots in the transmembrane domains of cystic fibrosis transmembrane conductance regulator (CFTR) channels and multidrug resistance protein (MRP) pumps. (24876383)
2014
12
Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes. (23894309)
2013
13
Colonic Atresia Presenting as Neonatal Bowel Obstruction in Cystic Fibrosis. (23059642)
2012
14
The cystic fibrosis F508del mutation in Crohn's disease. (21131241)
2011
15
Thermally unstable gating of the most common cystic fibrosis mutant channel (I9F508): &quot;rescue&quot; by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops. (21965669)
2011
16
Gray hair and acrodermatitis enteropathica-like dermatitis: an unexpected presentation of cystic fibrosis. (21424670)
2011
17
17Beta-estradiol inhibits IL-8 in cystic fibrosis by up-regulating secretory leucoprotease inhibitor. (20378727)
2010
18
Butyl-p-hydroxybenzoate stimulates cystic fibrosis transmembrane conductance regulator Cl- transport]. (19350818)
2009
19
The study of cystic fibrosis transmembrane conductance regulator gene mutations in a group of patients from Romania. (18467194)
2008
20
Potential role of high-mobility group box 1 in cystic fibrosis airway disease. (18658107)
2008
21
The expression of the mitochondrial gene MT-ND4 is downregulated in cystic fibrosis. (17382898)
2007
22
Dysfunction of the non-neuronal cholinergic system in the airways and blood cells of patients with cystic fibrosis. (17346753)
2007
23
Asians with cystic fibrosis in the UK have worse disease outcomes than clinic matched white homozygous delta F508 controls. (15752682)
2005
24
Thrombophilia in children with cystic fibrosis. (15678507)
2005
25
The role of cystic fibrosis gene mutations in determining susceptibility to chronic pancreatitis. (15528020)
2004
26
Induced sputum in cystic fibrosis: within-week reproducibility of inflammatory markers. (15498533)
2004
27
Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and chronic respiratory tract diseases]. (14593914)
2003
28
Development of a diagnostic PCR assay that targets a heat-shock protein gene (groES) for detection of Pseudomonas spp. in cystic fibrosis patients. (12909651)
2003
29
Antineutrophil cytoplasmic antibodies directed against bactericidal/permeability-increasing protein detected in children with cystic fibrosis inhibit neutrophil-mediated killing of Pseudomonas aeruginosa. (12593970)
2003
30
Emerging drug treatments for cystic fibrosis. (14662004)
2003
31
Progress toward generating a ferret model of cystic fibrosis by somatic cell nuclear transfer. (14613541)
2003
32
Mannose-binding lectin (MBL) therapy in an MBL-deficient patient with severe cystic fibrosis lung disease. (11836800)
2002
33
Cystic fibrosis transmembrane conductance regulator and H+ permeability in regulation of Golgi pH. (11875264)
2001
34
Restoration of bacterial killing activity of human respiratory cystic fibrosis cells through cationic vector-mediated cystic fibrosis transmembrane conductance regulator gene transfer. (10466626)
1999
35
Effects of short-term inhaled fluticasone on oxidative burst of sputum cells in cystic fibrosis patients. (10596705)
1999
36
Immunoreactive pancreatic Reg protein in sera from cystic fibrosis patients with and without pancreatic insufficiency. (10075963)
1999
37
Detection of a cystic fibrosis modifier locus for meconium ileus on human chromosome 19q13. (10369249)
1999
38
Comparison of fecal elastase-1 determination with the secretin-cholecystokinin test in patients with cystic fibrosis. (10192202)
1999
39
Regulation of electrogenic anion secretion in normal and cystic fibrosis gallbladder mucosa. (9862842)
1999
40
Channel-lining residues in the M3 membrane-spanning segment of the cystic fibrosis transmembrane conductance regulator. (9724537)
1998
41
Cystic fibrosis transmembrane conductance regulator expression in human hypothalamus. (9592064)
1998
42
Degradation of annexin I in bronchoalveolar lavage fluid from patients with cystic fibrosis. (9448053)
1998
43
Subdural empyema due to Burkholderia cepacia: an unusual complication after lung transplantation for cystic fibrosis. (9204013)
1997
44
Surfactant composition in infants and young children with cystic fibrosis. (9230741)
1997
45
Prevalence of allergic bronchopulmonary aspergillosis and atopy in adult patients with cystic fibrosis. (8769507)
1996
46
Clinical denouement and mutation analysis of patients with cystic fibrosis undergoing liver transplantation for biliary cirrhosis. (8523183)
1995
47
Two novel rare frameshift mutations (2423 del G in exon 13 and 1215 del G in exon 7) and one novel rare sequence variation (3271 + 18 C or T) identified in a patient with cystic fibrosis. (7524910)
1994
48
Molecular biology of cystic fibrosis. (7693108)
1993
49
Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line. (1569186)
1992
50
Expression patterns of genes encoding elastase and controlling mucoidy: co-ordinate regulation of two virulence factors in Pseudomonas aeruginosa isolates from cystic fibrosis. (2128528)
1990

Variations for Cystic Fibrosis

About this section

UniProtKB/Swiss-Prot genetic disease variations for Cystic Fibrosis:

68 (show all 133)
id Symbol AA change Variation ID SNP ID
1CFTRp.Ser13PheVAR_000101
2CFTRp.Arg31LeuVAR_000103
3CFTRp.Ser42PheVAR_000104
4CFTRp.Asp44GlyVAR_000105
5CFTRp.Trp57GlyVAR_000108
6CFTRp.Pro67LeuVAR_000109
7CFTRp.Arg74TrpVAR_000110rs115545701
8CFTRp.Gly85GluVAR_000112
9CFTRp.Phe87LeuVAR_000113
10CFTRp.Gly91ArgVAR_000114
11CFTRp.Glu92LysVAR_000115
12CFTRp.Gln98ArgVAR_000116
13CFTRp.Ile105SerVAR_000117
14CFTRp.Tyr109CysVAR_000118
15CFTRp.Asp110HisVAR_000119
16CFTRp.Arg117CysVAR_000121
17CFTRp.Arg117HisVAR_000122
18CFTRp.Arg117LeuVAR_000123
19CFTRp.Arg117ProVAR_000124
20CFTRp.Ala120ThrVAR_000125
21CFTRp.His139ArgVAR_000126
22CFTRp.Ala141AspVAR_000127
23CFTRp.Ile148ThrVAR_000128rs35516286
24CFTRp.Gly178ArgVAR_000130
25CFTRp.Glu193LysVAR_000132
26CFTRp.His199GlnVAR_000133
27CFTRp.His199TyrVAR_000134
28CFTRp.Pro205SerVAR_000135
29CFTRp.Leu206TrpVAR_000136
30CFTRp.Cys225ArgVAR_000137
31CFTRp.Asn287TyrVAR_000140
32CFTRp.Arg297GlnVAR_000141
33CFTRp.Tyr301CysVAR_000142rs150691494
34CFTRp.Ser307AsnVAR_000143
35CFTRp.Phe311LeuVAR_000144
36CFTRp.Gly314GluVAR_000146
37CFTRp.Gly314ArgVAR_000147
38CFTRp.Arg334TrpVAR_000148rs121909011
39CFTRp.Ile336LysVAR_000150
40CFTRp.Thr338IleVAR_000151
41CFTRp.Leu346ProVAR_000152
42CFTRp.Arg347HisVAR_000153
43CFTRp.Arg347LeuVAR_000154
44CFTRp.Arg347ProVAR_000155
45CFTRp.Arg352GlnVAR_000156
46CFTRp.Gln359LysVAR_000157
47CFTRp.Ala455GluVAR_000160
48CFTRp.Val456PheVAR_000161
49CFTRp.Gly458ValVAR_000162
50CFTRp.Gly480CysVAR_000165
51CFTRp.Ser492PheVAR_000166
52CFTRp.Glu504GlnVAR_000167
53CFTRp.Val520PheVAR_000174rs77646904
54CFTRp.Ser549AsnVAR_000176
55CFTRp.Ser549IleVAR_000177
56CFTRp.Ser549ArgVAR_000178
57CFTRp.Gly551AspVAR_000179
58CFTRp.Gly551SerVAR_000180
59CFTRp.Arg553GlnVAR_000181
60CFTRp.Leu558SerVAR_000182
61CFTRp.Ala559ThrVAR_000183
62CFTRp.Arg560LysVAR_000184
63CFTRp.Arg560SerVAR_000185
64CFTRp.Arg560ThrVAR_000186
65CFTRp.Val562LeuVAR_000188rs1800097
66CFTRp.Tyr563AsnVAR_000189
67CFTRp.Tyr569CysVAR_000190
68CFTRp.Tyr569AspVAR_000191
69CFTRp.Tyr569HisVAR_000192
70CFTRp.Leu571SerVAR_000193
71CFTRp.Asp572AsnVAR_000194
72CFTRp.Pro574HisVAR_000195
73CFTRp.Asp579GlyVAR_000197
74CFTRp.Ile601PheVAR_000198
75CFTRp.Leu610SerVAR_000199
76CFTRp.Ala613ThrVAR_000200rs201978662
77CFTRp.Asp614GlyVAR_000201rs201124247
78CFTRp.Ile618ThrVAR_000202
79CFTRp.Leu619SerVAR_000203
80CFTRp.His620ProVAR_000204
81CFTRp.His620GlnVAR_000205
82CFTRp.Gly628ArgVAR_000207
83CFTRp.Leu633ProVAR_000208
84CFTRp.Asp648ValVAR_000209
85CFTRp.Asp651AsnVAR_000210
86CFTRp.Thr665SerVAR_000211
87CFTRp.Val754MetVAR_000214rs150157202
88CFTRp.Glu822LysVAR_000219
89CFTRp.Cys866TyrVAR_000221
90CFTRp.Tyr913CysVAR_000223
91CFTRp.Tyr917CysVAR_000224
92CFTRp.His949TyrVAR_000225
93CFTRp.Met952IleVAR_000226
94CFTRp.Leu997PheVAR_000227rs1800111
95CFTRp.Ile1005ArgVAR_000228
96CFTRp.Ala1006GluVAR_000229
97CFTRp.Pro1013LeuVAR_000230
98CFTRp.Met1028IleVAR_000231
99CFTRp.Phe1052ValVAR_000232
100CFTRp.Gly1061ArgVAR_000233rs142394380
101CFTRp.Leu1065ProVAR_000234
102CFTRp.Leu1065ArgVAR_000235
103CFTRp.Arg1066CysVAR_000236
104CFTRp.Arg1066HisVAR_000237
105CFTRp.Arg1066LeuVAR_000238
106CFTRp.Ala1067ThrVAR_000239
107CFTRp.Arg1070GlnVAR_000241
108CFTRp.Arg1070ProVAR_000242
109CFTRp.Gln1071ProVAR_000243
110CFTRp.Pro1072LeuVAR_000244
111CFTRp.Leu1077ProVAR_000245
112CFTRp.His1085ArgVAR_000246
113CFTRp.Trp1098ArgVAR_000247
114CFTRp.Met1101LysVAR_000248rs36210737
115CFTRp.Met1137ValVAR_000249
116CFTRp.Asp1152HisVAR_000251
117CFTRp.Ile1234ValVAR_000254
118CFTRp.Ser1235ArgVAR_000255rs34911792
119CFTRp.Gly1244GluVAR_000256
120CFTRp.Gly1249GluVAR_000257
121CFTRp.Ser1251AsnVAR_000258
122CFTRp.Ser1255ProVAR_000259
123CFTRp.Asp1270AsnVAR_000260rs11971167
124CFTRp.Trp1282ArgVAR_000261
125CFTRp.Arg1283MetVAR_000262
126CFTRp.Phe1286SerVAR_000263
127CFTRp.Gln1291HisVAR_000264
128CFTRp.Gln1291ArgVAR_000265
129CFTRp.Asn1303HisVAR_000266
130CFTRp.Asn1303LysVAR_000267rs80034486
131CFTRp.Gly1349AspVAR_000268
132CFTRp.Val1397GluVAR_000270
133CFTRp.Met1101ArgVAR_011565

Clinvar genetic disease variations for Cystic Fibrosis:

5 (show all 363)
id Gene Variation Type Significance SNP ID Assembly Location
1TGFB1NM_000660.6(TGFB1): c.29C> T (p.Pro10Leu)single nucleotide variantrisk factorrs1800470GRCh37Chr 19, 41858921: 41858921
2CFTRNM_000492.3(CFTR): c.3963+1G> Asingle nucleotide variantPathogenicrs672601314GRCh38Chr 7, 117652932: 117652932
3CFTRNM_000492.3(CFTR): c.2700T> A (p.Asn900Lys)single nucleotide variantPathogenicrs672601315GRCh38Chr 7, 117603574: 117603574
4CFTRNM_000492.3(CFTR): c.1117G> A (p.Asp373Asn)single nucleotide variantPathogenicrs556880586GRCh38Chr 7, 117542016: 117542016
5CFTRNM_000492.3(CFTR): c.2443G> T (p.Glu815Ter)single nucleotide variantPathogenicrs672601316GRCh37Chr 7, 117232664: 117232664
6CFTRNM_000492.3(CFTR): c.830G> A (p.Trp277Ter)single nucleotide variantPathogenicrs672601317GRCh38Chr 7, 117536634: 117536634
7CFTRNM_000492.3(CFTR): c.1210-11T> Gsingle nucleotide variantLikely pathogenicrs73715573GRCh37Chr 7, 117188684: 117188684
8CFTRNM_000492.3(CFTR): c.1210-7_1210-6delTTdeletionPathogenicrs727504486GRCh37Chr 7, 117188688: 117188689
9CFTRNM_000492.3(CFTR): c.3368-2A> Gsingle nucleotide variantPathogenicrs755416052GRCh37Chr 7, 117254665: 117254665
10CFTRNM_000492.3(CFTR): c.1327_1330dupGATA (p.Ile444Argfs)duplicationPathogenicrs397508189GRCh37Chr 7, 117188812: 117188815
11CFTRNM_000492.3(CFTR): c.850dupA (p.Met284Asnfs)duplicationLikely pathogenicrs786204693GRCh37Chr 7, 117176708: 117176708
12CFTRNM_000492.3(CFTR): c.220C> T (p.Arg74Trp)single nucleotide variantLikely pathogenicrs115545701GRCh37Chr 7, 117149143: 117149143
13CFTRNM_000492.3(CFTR): c.848_860delAAATGATTGAAAAinsTG (p.Lys283Metfs)indelPathogenicrs796065332GRCh37Chr 7, 117176706: 117176718
14CFTRNM_000492.3(CFTR): c.2462_2463delGT (p.Ser821Argfs)deletionPathogenicrs797045156GRCh37Chr 7, 117232683: 117232684
15CFTRNM_000492.3(CFTR): c.2658-1G> Csingle nucleotide variantPathogenicrs397508416GRCh38Chr 7, 117603531: 117603531
16CFTRNM_000492.3(CFTR): c.2423_2424dupAT (p.Ser809Ilefs)duplicationPathogenicrs387906359GRCh37Chr 7, 117232644: 117232645
17CFTRNM_000492.3(CFTR): c.350G> A (p.Arg117His)single nucleotide variantPathogenicrs78655421GRCh37Chr 7, 117171029: 117171029
18CFTRNM_000492.3(CFTR): c.(2988+1_2989-1)_(3468+1_3469-1)deldeletionPathogenic
19CFTRNM_000492.3(CFTR): c.(53+1_54-1)_(164+1_165-1)deldeletionPathogenic
20CFTRNM_000492.3(CFTR): c.(3963+1_3964-1)_(*1_?)deldeletionPathogenic
21CFTRNM_000492.3(CFTR): c.(2619+1_2620-1)_(3367+1_3368-1)deldeletionPathogenic
22CFTRNM_000492.3(CFTR): c.(2988+1_2989-1)_(3367+1_3368-1)deldeletionPathogenic
23CFTRNM_000492.3(CFTR): c.(743+1_744-1)_(1584+1_1585-1)dupduplicationPathogenic
24CFTRNM_000492.3(CFTR): c.3899dupT (p.Arg1301Terfs)duplicationPathogenicrs797045158GRCh37Chr 7, 117292921: 117292921
25CFTRNM_000492.3(CFTR): c.(2908+1_2909-1)_(3367+1_3368-1)deldeletionPathogenic
26CFTRNM_000492.3(CFTR): c.3747delG (p.Lys1250Argfs)deletionPathogenicrs797045159GRCh37Chr 7, 117282521: 117282521
27CFTRNM_000492.3(CFTR): c.3294G> A (p.Trp1098Ter)single nucleotide variantPathogenicrs397508533GRCh37Chr 7, 117251789: 117251789
28CFTRNM_000492.3(CFTR): c.(3468+1_3469-1)_(3717+1_3718-1)deldeletionPathogenic
29CFTRNM_000492.3(CFTR): c.1117-1G> Asingle nucleotide variantPathogenicrs797045160GRCh37Chr 7, 117182069: 117182069
30CFTRNM_000492.3(CFTR): c.(?_1)_(53+1_54-1)deldeletionPathogenic
31CFTRNM_000492.3(CFTR): c.1365_1366delGG (p.Val456Cysfs)deletionPathogenicrs797045161GRCh38Chr 7, 117548796: 117548797
32CFTRNM_000492.3(CFTR): c.(273+1_274-1)_(1116+1_1117-1)deldeletionPathogenic
33CFTRNM_000492.3(CFTR)deletionPathogenic
34CFTRNM_000492.3(CFTR): c.(1584+1_1585-1)_(1679+1_1680-1)deldeletionPathogenic
35CFTRNM_000492.3(CFTR): c.(53+1_54-1)_(489+1_490-1)deldeletionPathogenic
36CFTRNM_000492.3(CFTR): c.2053dupC (p.Gln685Profs)duplicationPathogenicrs797045162GRCh37Chr 7, 117232274: 117232274
37CFTRNM_000492.3(CFTR): c.(1766+1_1767-1)_(2619+1_2620-1)deldeletionPathogenic
38CFTRNM_000492.3(CFTR): c.114C> G (p.Tyr38Ter)single nucleotide variantLikely pathogenicrs193922498GRCh37Chr 7, 117144367: 117144367
39CFTRNM_000492.3(CFTR): c.1367T> C (p.Val456Ala)single nucleotide variantLikely pathogenicrs193922500GRCh37Chr 7, 117188852: 117188852
40CFTRNM_000492.3(CFTR): c.1397C> G (p.Ser466Ter)single nucleotide variantPathogenicrs121908805GRCh37Chr 7, 117199522: 117199522
41CFTRNM_000492.3(CFTR): c.1400T> C (p.Leu467Pro)single nucleotide variantPathogenicrs139573311GRCh37Chr 7, 117199525: 117199525
42CFTRNM_000492.3(CFTR): c.14C> T (p.Pro5Leu)single nucleotide variantLikely pathogenic, Pathogenicrs193922501GRCh37Chr 7, 117120162: 117120162
43CFTRNM_000492.3(CFTR): c.1585-8G> Asingle nucleotide variantPathogenicrs193922503GRCh37Chr 7, 117227785: 117227785
44CFTRNM_000492.3(CFTR): c.1673T> C (p.Leu558Ser)single nucleotide variantLikely pathogenicrs193922504GRCh37Chr 7, 117227881: 117227881
45CFTRNM_000492.3(CFTR): c.1692delA (p.Asp565Metfs)deletionPathogenicrs193922505GRCh37Chr 7, 117230419: 117230419
46CFTRNM_000492.3(CFTR): c.1865G> A (p.Gly622Asp)single nucleotide variantPathogenicrs121908759GRCh37Chr 7, 117232086: 117232086
47CFTRNM_000492.3(CFTR): c.1911delG (p.Gln637Hisfs)deletionPathogenicrs121908778GRCh37Chr 7, 117232132: 117232132
48CFTRNM_000492.3(CFTR): c.2012delT (p.Leu671Terfs)deletionPathogenicrs121908812GRCh37Chr 7, 117232233: 117232233
49CFTRNM_000492.3(CFTR): c.2051_2052delAAinsG (p.Lys684Serfs)indelPathogenicGRCh37Chr 7, 117232272: 117232273
50CFTRNM_000492.3(CFTR): c.2052dupA (p.Gln685Thrfs)duplicationPathogenicrs121908786GRCh37Chr 7, 117232273: 117232273
51CFTRNM_000492.3(CFTR): c.273+3A> Csingle nucleotide variantPathogenicrs74467662GRCh37Chr 7, 117149199: 117149199
52CFTRNM_000492.3(CFTR): c.2768C> A (p.Ala923Asp)single nucleotide variantLikely pathogenicrs193922509GRCh37Chr 7, 117243696: 117243696
53CFTRNM_000492.3(CFTR): c.2810dupT (p.Val938Glyfs)duplicationPathogenicrs193922510GRCh37Chr 7, 117243738: 117243738
54CFTRNM_000492.3(CFTR): c.2813T> G (p.Val938Gly)single nucleotide variantPathogenicrs193922511GRCh37Chr 7, 117243741: 117243741
55CFTRNM_000492.3(CFTR): c.2909G> A (p.Gly970Asp)single nucleotide variantLikely pathogenicrs386134230GRCh37Chr 7, 117246728: 117246728
56CFTRNM_000492.3(CFTR): c.2932A> T (p.Lys978Ter)single nucleotide variantLikely pathogenicrs193922514GRCh37Chr 7, 117246751: 117246751
57CFTRNM_000492.3(CFTR): c.2988G> A (p.Gln996=)single nucleotide variantPathogenicrs121908797GRCh37Chr 7, 117246807: 117246807
58CFTRNM_000492.3(CFTR): c.2989-2A> Tsingle nucleotide variantLikely pathogenicrs193922515GRCh37Chr 7, 117250571: 117250571
59CFTRNM_000492.3(CFTR): c.3038C> A (p.Pro1013His)single nucleotide variantLikely pathogenicrs193922516GRCh37Chr 7, 117250622: 117250622
60CFTRNM_000492.3(CFTR): c.3095A> G (p.Tyr1032Cys)single nucleotide variantPathogenicrs144055758GRCh37Chr 7, 117250679: 117250679
61CFTRNM_000492.3(CFTR): c.3140-26A> Gsingle nucleotide variantPathogenicrs76151804GRCh37Chr 7, 117251609: 117251609
62CFTRNM_000492.3(CFTR): c.3154T> G (p.Phe1052Val)single nucleotide variantLikely pathogenic, Pathogenicrs150212784GRCh37Chr 7, 117251649: 117251649
63CFTRNM_000492.3(CFTR): c.3209G> A (p.Arg1070Gln)single nucleotide variantLikely pathogenic, Pathogenicrs78769542GRCh37Chr 7, 117251704: 117251704
64CFTRNM_000492.3(CFTR): c.3454G> C (p.Asp1152His)single nucleotide variantPathogenicrs75541969GRCh37Chr 7, 117254753: 117254753
65CFTRNM_000492.3(CFTR): c.3528delC (p.Lys1177Serfs)deletionPathogenicrs121908747GRCh37Chr 7, 117267635: 117267635
66CFTRNM_000492.3(CFTR): c.355A> G (p.Ile119Val)single nucleotide variantLikely pathogenicrs193922518GRCh37Chr 7, 117171034: 117171034
67CFTRNM_000492.3(CFTR): c.3691delT (p.Ser1231Profs)deletionPathogenicrs121908783GRCh37Chr 7, 117267798: 117267798
68CFTRNM_000492.3(CFTR): c.370G> C (p.Gly124Arg)single nucleotide variantLikely pathogenicrs193922519GRCh37Chr 7, 117171049: 117171049
69CFTRNM_000492.3(CFTR): c.3717+5G> Asingle nucleotide variantLikely pathogenicrs193922520GRCh37Chr 7, 117267829: 117267829
70CFTRNM_000492.3(CFTR): c.380_382dupTAT (p.Leu127_Cys128insLeu)duplicationLikely pathogenicrs193922521GRCh37Chr 7, 117171059: 117171061
71CFTRNM_000492.3(CFTR): c.3957_3958insAGGG (p.Asp1320Argfs)insertionLikely pathogenicrs193922523GRCh37Chr 7, 117292979: 117292980
72CFTRNM_000492.3(CFTR): c.3997G> T (p.Gly1333Trp)single nucleotide variantLikely pathogenicrs193922524GRCh37Chr 7, 117304775: 117304775
73CFTRNM_000492.3(CFTR): c.4046G> A (p.Gly1349Asp)single nucleotide variantPathogenic, drug responsers193922525GRCh37Chr 7, 117304824: 117304824
74CFTRNM_000492.3(CFTR): c.4242+2T> Csingle nucleotide variantLikely pathogenicrs193922526GRCh37Chr 7, 117305620: 117305620
75CFTRNM_000492.3(CFTR): c.4280T> C (p.Ile1427Thr)single nucleotide variantLikely pathogenicrs193922528GRCh37Chr 7, 117306999: 117306999
76CFTRNM_000492.3(CFTR): c.592G> A (p.Ala198Thr)single nucleotide variantLikely pathogenicrs193922529GRCh37Chr 7, 117175314: 117175314
77CFTRNM_000492.3(CFTR): c.825C> G (p.Tyr275Ter)single nucleotide variantPathogenicrs193922532GRCh37Chr 7, 117176683: 117176683
78CFTRNM_000492.3(CFTR): c.846A> T (p.Glu282Asp)single nucleotide variantLikely pathogenicrs142864834GRCh37Chr 7, 117176704: 117176704
79CFTRNM_000492.3(CFTR): c.997C> T (p.Leu333Phe)single nucleotide variantLikely pathogenicrs193922533GRCh37Chr 7, 117180281: 117180281
80CFTRNM_000492.3(CFTR): c.3067_3072delATAGTG (p.Ile1023_Val1024del)deletionPathogenicrs121908767GRCh37Chr 7, 117250651: 117250656
81CFTRNM_000492.3(CFTR): c.2052delA (p.Lys684Asnfs)deletionPathogenicrs121908746GRCh37Chr 7, 117232273: 117232273
82CFTRNM_000492.3(CFTR): c.579+1G> Tsingle nucleotide variantPathogenicrs77188391GRCh37Chr 7, 117174420: 117174420
83CFTRNM_000492.3(CFTR): c.2657+5G> Asingle nucleotide variantPathogenicrs80224560GRCh37Chr 7, 117242922: 117242922
84CFTRNM_000492.3(CFTR): c.3773dupT (p.Leu1258Phefs)duplicationPathogenicrs121908789GRCh37Chr 7, 117282547: 117282547
85CFTRNM_000492.3(CFTR): c.3276C> A (p.Tyr1092Ter)single nucleotide variantPathogenicrs121908761GRCh37Chr 7, 117251771: 117251771
86CFTRNM_000492.3(CFTR): c.178G> T (p.Glu60Ter)single nucleotide variantPathogenicrs77284892GRCh37Chr 7, 117149101: 117149101
87CFTRNM_000492.3(CFTR): c.1645A> C (p.Ser549Arg)single nucleotide variantPathogenic, drug responsers121908757GRCh37Chr 7, 117227853: 117227853
88CFTRNM_000492.3(CFTR): c.1923_1931delCTCAAAACTinsA (p.Ser641Argfs)indelPathogenicrs121908779GRCh37Chr 7, 117232144: 117232152
89CFTRNM_000492.3(CFTR): c.489+1G> Tsingle nucleotide variantPathogenicrs78756941GRCh37Chr 7, 117171169: 117171169
90CFTRNM_000492.3(CFTR): c.366T> A (p.Tyr122Ter)single nucleotide variantPathogenicrs79660178GRCh37Chr 7, 117171045: 117171045
91CFTRNM_000492.3(CFTR): c.3302T> A (p.Met1101Lys)single nucleotide variantPathogenicrs36210737GRCh37Chr 7, 117251797: 117251797
92CFTRNM_000492.3(CFTR): c.3276C> G (p.Tyr1092Ter)single nucleotide variantPathogenicrs121908761GRCh37Chr 7, 117251771: 117251771
93CFTRNM_000492.3(CFTR): c.1647T> G (p.Ser549Arg)single nucleotide variantPathogenic, drug responsers121909005GRCh37Chr 7, 117227855: 117227855
94CFTRNM_000492.3(CFTR): c.223C> T (p.Arg75Ter)single nucleotide variantPathogenicrs121908749GRCh37Chr 7, 117149146: 117149146
95CFTRNM_000492.3(CFTR): c.3587C> G (p.Ser1196Ter)single nucleotide variantPathogenicrs121908763GRCh37Chr 7, 117267694: 117267694
96CFTRNM_000492.3(CFTR): c.274-1G> Asingle nucleotide variantPathogenicrs121908792GRCh37Chr 7, 117170952: 117170952
97CFTRNM_000492.3(CFTR): c.1680-1G> Asingle nucleotide variantPathogenicrs121908794GRCh37Chr 7, 117230406: 117230406
98CFTRNM_000492.3(CFTR): c.313delA (p.Ile105Serfs)deletionPathogenicrs121908801GRCh37Chr 7, 117170992: 117170992
99CFTRNM_000492.3(CFTR): c.349C> T (p.Arg117Cys)single nucleotide variantPathogenicrs77834169GRCh37Chr 7, 117171028: 117171028
100CFTRNM_000492.3(CFTR): c.532G> A (p.Gly178Arg)single nucleotide variantPathogenic, drug responsers80282562GRCh37Chr 7, 117174372: 117174372
101CFTRNM_000492.3(CFTR): c.803delA (p.Asn268Ilefs)deletionPathogenicrs121908772GRCh37Chr 7, 117176661: 117176661
102CFTRNM_000492.3(CFTR): c.935_937delTCT (p.Phe312del)deletionPathogenicrs121908768GRCh37Chr 7, 117180219: 117180221
103CFTRNM_000492.3(CFTR): c.988G> T (p.Gly330Ter)single nucleotide variantPathogenicrs79031340GRCh37Chr 7, 117180272: 117180272
104CFTRNM_000492.3(CFTR): c.2989-977_3367+248deldeletionPathogenicGRCh37Chr 7, 117249596: 117252110
105CFTRNM_000492.3(CFTR): c.-9_14del23deletionPathogenicrs397508136GRCh37Chr 7, 117120140: 117120162
106CFTRNM_000492.3(CFTR): c.1006_1007insG (p.Ile336Serfs)insertionPathogenicrs397508138GRCh37Chr 7, 117180290: 117180291
107CFTRNM_000492.3(CFTR): c.1007T> A (p.Ile336Lys)single nucleotide variantPathogenicrs397508139GRCh37Chr 7, 117180291: 117180291
108CFTRNM_000492.3(CFTR): c.1021T> C (p.Ser341Pro)single nucleotide variantPathogenicrs397508144GRCh37Chr 7, 117180305: 117180305
109CFTRNM_000492.3(CFTR): c.1029delC (p.Cys343Terfs)deletionPathogenicrs121908774GRCh37Chr 7, 117180313: 117180313
110CFTRNM_000492.3(CFTR): c.1116+1G> Asingle nucleotide variantPathogenicrs397508158GRCh37Chr 7, 117180401: 117180401
111CFTRNM_000492.3(CFTR): c.1128dupA (p.Gln378Alafs)duplicationPathogenicrs397508163GRCh37Chr 7, 117182081: 117182081
112CFTRNM_000492.3(CFTR): c.1152_1153dupAT (p.Asn386Ilefs)duplicationPathogenicrs121908785GRCh37Chr 7, 117182105: 117182106
113CFTRNM_000492.3(CFTR): c.115C> T (p.Gln39Ter)single nucleotide variantPathogenicrs397508168GRCh37Chr 7, 117144368: 117144368
114CFTRNM_000492.3(CFTR): c.11C> A (p.Ser4Ter)single nucleotide variantPathogenicrs397508173GRCh37Chr 7, 117120159: 117120159
115CFTRNM_000492.3(CFTR): c.1202G> A (p.Trp401Ter)single nucleotide variantPathogenicrs397508174GRCh37Chr 7, 117182155: 117182155
116CFTRNM_000492.3(CFTR): c.1203G> A (p.Trp401Ter)single nucleotide variantPathogenicrs397508175GRCh37Chr 7, 117182156: 117182156
117CFTRNM_000492.3(CFTR): c.1209+1G> Asingle nucleotide variantPathogenicrs397508176GRCh37Chr 7, 117182163: 117182163
118CFTRNM_000492.3(CFTR): c.1240C> T (p.Gln414Ter)single nucleotide variantPathogenicrs397508183GRCh37Chr 7, 117188725: 117188725
119CFTRNM_000492.3(CFTR): c.1327G> T (p.Asp443Tyr)single nucleotide variantPathogenicrs147422190GRCh37Chr 7, 117188812: 117188812
120CFTRNM_000492.3(CFTR): c.1340delA (p.Lys447Argfs)deletionPathogenicrs397508192GRCh37Chr 7, 117188825: 117188825
121CFTRNM_000492.3(CFTR): c.137C> A (p.Ala46Asp)single nucleotide variantPathogenicrs151020603GRCh37Chr 7, 117144390: 117144390
122CFTRNM_000492.3(CFTR): c.1393-1G> Asingle nucleotide variantPathogenicrs397508200GRCh37Chr 7, 117199517: 117199517
123CFTRNM_000492.3(CFTR): c.1393-2A> Gsingle nucleotide variantPathogenicrs397508201GRCh37Chr 7, 117199516: 117199516
124CFTRNM_000492.3(CFTR): c.1397C> A (p.Ser466Ter)single nucleotide variantPathogenicrs121908805GRCh37Chr 7, 117199522: 117199522
125CFTRNM_000492.3(CFTR): c.1418delG (p.Gly473Glufs)deletionPathogenicrs397508205GRCh37Chr 7, 117199543: 117199543
126CFTRNM_000492.3(CFTR): c.1466C> A (p.Ser489Ter)single nucleotide variantPathogenicrs397508211GRCh37Chr 7, 117199591: 117199591
127CFTRNM_000492.3(CFTR): c.1518C> G (p.Ile506Met)single nucleotide variantPathogenicrs1800092GRCh37Chr 7, 117199643: 117199643
128CFTRNM_000492.3(CFTR): c.1573C> T (p.Gln525Ter)single nucleotide variantPathogenicrs397508227GRCh37Chr 7, 117199698: 117199698
129CFTRNM_000492.3(CFTR): c.164+1G> Asingle nucleotide variantPathogenicrs397508243GRCh37Chr 7, 117144418: 117144418
130CFTRNM_000492.3(CFTR): c.1648G> T (p.Gly550Ter)single nucleotide variantPathogenicrs397508247GRCh37Chr 7, 117227856: 117227856
131CFTRNM_000492.3(CFTR): c.165-1G> Asingle nucleotide variantPathogenicrs397508249GRCh37Chr 7, 117149087: 117149087
132CFTRNM_000492.3(CFTR): c.165-3C> Tsingle nucleotide variantLikely pathogenicrs200337193GRCh37Chr 7, 117149085: 117149085
133CFTRNM_000492.3(CFTR): c.1650delA (p.Gly551Valfs)deletionPathogenicrs397508251GRCh37Chr 7, 117227858: 117227858
134CFTRNM_000492.3(CFTR): c.166G> A (p.Glu56Lys)single nucleotide variantPathogenicrs397508256GRCh37Chr 7, 117149089: 117149089
135CFTRNM_000492.3(CFTR): c.1679+1G> Csingle nucleotide variantPathogenicrs397508263GRCh37Chr 7, 117227888: 117227888
136CFTRNM_000492.3(CFTR): c.1705T> G (p.Tyr569Asp)single nucleotide variantPathogenicrs397508276GRCh37Chr 7, 117230432: 117230432
137CFTRNM_000492.3(CFTR): c.170G> A (p.Trp57Ter)single nucleotide variantPathogenicrs397508279GRCh37Chr 7, 117149093: 117149093
138CFTRNM_000492.3(CFTR): c.175dupA (p.Arg59Lysfs)duplicationPathogenicrs397508294GRCh37Chr 7, 117149098: 117149098
139CFTRNM_000492.3(CFTR): c.1753G> T (p.Glu585Ter)single nucleotide variantPathogenicrs397508296GRCh37Chr 7, 117230480: 117230480
140CFTRNM_000492.3(CFTR): c.1766+1G> Csingle nucleotide variantPathogenicrs121908748GRCh37Chr 7, 117230494: 117230494
141CFTRNM_000492.3(CFTR): c.1766+3A> Gsingle nucleotide variantPathogenicrs397508298GRCh37Chr 7, 117230496: 117230496
142CFTRNM_000492.3(CFTR): c.1792_1798delAAAACTA (p.Lys598Glyfs)deletionPathogenicrs397508303GRCh37Chr 7, 117232013: 117232019
143CFTRNM_000492.3(CFTR): c.1820_1903del84 (p.Met607_Gln634del)deletionLikely pathogenic, Pathogenicrs121908777GRCh37Chr 7, 117232041: 117232124
144CFTRNM_000492.3(CFTR): c.1853T> C (p.Ile618Thr)single nucleotide variantPathogenicrs139468767GRCh37Chr 7, 117232074: 117232074
145CFTRNM_000492.3(CFTR): c.1973_1985delGAAATTCAATCCTinsAGAAA (p.Arg658Lysfs)indelPathogenicrs121908780GRCh37Chr 7, 117232194: 117232206
146CFTRNM_000492.3(CFTR): c.1986_1989delAACT (p.Thr663Argfs)deletionPathogenicrs397508325GRCh37Chr 7, 117232207: 117232210
147CFTRNM_000492.3(CFTR): c.1A> G (p.Met1Val)single nucleotide variantPathogenicrs397508328GRCh37Chr 7, 117120149: 117120149
148CFTRNM_000492.3(CFTR): c.200C> T (p.Pro67Leu)single nucleotide variantPathogenicrs368505753GRCh37Chr 7, 117149123: 117149123
149CFTRNM_000492.3(CFTR): c.2017G> T (p.Gly673Ter)single nucleotide variantPathogenicrs397508331GRCh37Chr 7, 117232238: 117232238
150CFTRNM_000492.3(CFTR): c.2036G> A (p.Trp679Ter)single nucleotide variantLikely pathogenicrs397508333GRCh37Chr 7, 117232257: 117232257
151CFTRNM_000492.3(CFTR): c.2053C> T (p.Gln685Ter)single nucleotide variantPathogenicrs397508336GRCh37Chr 7, 117232274: 117232274
152CFTRNM_000492.3(CFTR): c.2125C> T (p.Arg709Ter)single nucleotide variantPathogenicrs121908760GRCh37Chr 7, 117232346: 117232346
153CFTRNM_000492.3(CFTR): c.2195T> G (p.Leu732Ter)single nucleotide variantPathogenicrs397508350GRCh37Chr 7, 117232416: 117232416
154CFTRNM_000492.3(CFTR): c.2215delG (p.Val739Tyrfs)deletionPathogenicrs397508353GRCh37Chr 7, 117232436: 117232436
155CFTRNM_000492.3(CFTR): c.2290C> T (p.Arg764Ter)single nucleotide variantPathogenicrs121908810GRCh37Chr 7, 117232511: 117232511
156CFTRNM_000492.3(CFTR): c.233dupT (p.Trp79Leufs)duplicationPathogenicrs397508360GRCh37Chr 7, 117149156: 117149156
157CFTRNM_000492.3(CFTR): c.2353C> T (p.Arg785Ter)single nucleotide variantPathogenicrs374946172GRCh37Chr 7, 117232574: 117232574
158CFTRNM_000492.3(CFTR): c.2374C> T (p.Arg792Ter)single nucleotide variantPathogenicrs145449046GRCh37Chr 7, 117232595: 117232595
159CFTRNM_000492.3(CFTR): c.2464G> T (p.Glu822Ter)single nucleotide variantPathogenicrs397508378GRCh37Chr 7, 117232685: 117232685
160CFTRNM_000492.3(CFTR): c.2491G> T (p.Glu831Ter)single nucleotide variantPathogenicrs397508387GRCh37Chr 7, 117234984: 117234984
161CFTRNM_000492.3(CFTR): c.2506G> T (p.Asp836Tyr)single nucleotide variantLikely pathogenicrs201386642GRCh37Chr 7, 117234999: 117234999
162CFTRNM_000492.3(CFTR): c.2537G> A (p.Trp846Ter)single nucleotide variantPathogenicrs397508393GRCh37Chr 7, 117235030: 117235030
163CFTRNM_000492.3(CFTR): c.2547C> A (p.Tyr849Ter)single nucleotide variantPathogenicrs397508394GRCh37Chr 7, 117235040: 117235040
164CFTRNM_000492.3(CFTR): c.2583delT (p.Phe861Leufs)deletionPathogenicrs397508399GRCh37Chr 7, 117235076: 117235076
165CFTRNM_000492.3(CFTR): c.2589_2599delAATTTGGTGCT (p.Ile864Serfs)deletionPathogenicrs397508400GRCh37Chr 7, 117235082: 117235092
166CFTRNM_000492.3(CFTR): c.2601dupA (p.Val868Serfs)duplicationPathogenicrs397508405GRCh37Chr 7, 117235094: 117235094
167CFTRNM_000492.3(CFTR): c.2657+2_2657+3insAinsertionPathogenicrs397508414GRCh37Chr 7, 117242919: 117242920
168CFTRNM_000492.3(CFTR): c.273+1G> Asingle nucleotide variantPathogenicrs121908791GRCh37Chr 7, 117149197: 117149197
169CFTRNM_000492.3(CFTR): c.2735C> A (p.Ser912Ter)single nucleotide variantPathogenicrs121909034GRCh37Chr 7, 117243663: 117243663
170CFTRNM_000492.3(CFTR): c.2739T> A (p.Tyr913Ter)single nucleotide variantPathogenicrs149790377GRCh37Chr 7, 117243667: 117243667
171CFTRNM_000492.3(CFTR): c.2763_2764dupAG (p.Val922Glufs)duplicationPathogenicrs397508431GRCh37Chr 7, 117243691: 117243692
172CFTRNM_000492.3(CFTR): c.2780T> C (p.Leu927Pro)single nucleotide variantPathogenicrs397508435GRCh37Chr 7, 117243708: 117243708
173CFTRNM_000492.3(CFTR): c.2825delT (p.Ile942Thrfs)deletionPathogenicrs397508441GRCh37Chr 7, 117243753: 117243753
174CFTRNM_000492.3(CFTR): c.2834C> T (p.Ser945Leu)single nucleotide variantPathogenicrs397508442GRCh37Chr 7, 117243762: 117243762
175CFTRNM_000492.3(CFTR): c.2859_2890del32 (p.Leu953Phefs)deletionPathogenicrs397508445GRCh37Chr 7, 117243787: 117243818
176CFTRNM_000492.3(CFTR): c.2875delG (p.Ala959Hisfs)deletionPathogenicrs397508447GRCh37Chr 7, 117243803: 117243803
177CFTRNM_000492.3(CFTR): c.2896delA (p.Thr966Argfs)deletionPathogenicrs397508451GRCh37Chr 7, 117243824: 117243824
178CFTRNM_000492.3(CFTR): c.2908G> C (p.Gly970Arg)single nucleotide variantPathogenicrs397508453GRCh37Chr 7, 117243836: 117243836
179CFTRNM_000492.3(CFTR): c.292C> T (p.Gln98Ter)single nucleotide variantPathogenicrs397508461GRCh37Chr 7, 117170971: 117170971
180CFTRNM_000492.3(CFTR): c.2989-1G> Asingle nucleotide variantPathogenicrs397508470GRCh37Chr 7, 117250572: 117250572
181CFTRNM_000492.3(CFTR): c.2989-2A> Gsingle nucleotide variantPathogenicrs193922515GRCh37Chr 7, 117250571: 117250571
182CFTRNM_000492.3(CFTR): c.2T> C (p.Met1Thr)single nucleotide variantLikely pathogenicrs397508476GRCh37Chr 7, 117120150: 117120150
183CFTRNM_000492.3(CFTR): c.3002_3003delTG (p.Val1001Aspfs)deletionPathogenicrs397508477GRCh37Chr 7, 117250586: 117250587
184CFTRNM_000492.3(CFTR): c.3022delG (p.Val1008Serfs)deletionLikely pathogenicrs397508482GRCh37Chr 7, 117250606: 117250606
185CFTRNM_000492.3(CFTR): c.3039delC (p.Tyr1014Thrfs)deletionPathogenicrs121908781GRCh37Chr 7, 117250623: 117250623
186CFTRNM_000492.3(CFTR): c.310delA (p.Arg104Glufs)deletionPathogenicrs397508499GRCh37Chr 7, 117170989: 117170989
187CFTRNM_000492.3(CFTR): c.3139_3139+1delGGdeletionLikely pathogenicrs397508505GRCh37Chr 7, 117250723: 117250724
188CFTRNM_000492.3(CFTR): c.3160C> G (p.His1054Asp)single nucleotide variantPathogenicrs397508510GRCh37Chr 7, 117251655: 117251655
189CFTRNM_000492.3(CFTR): c.3181G> C (p.Gly1061Arg)single nucleotide variantPathogenicrs142394380GRCh37Chr 7, 117251676: 117251676
190CFTRNM_000492.3(CFTR): c.3208C> T (p.Arg1070Trp)single nucleotide variantPathogenicrs202179988GRCh37Chr 7, 117251703: 117251703
191CFTRNM_000492.3(CFTR): c.3222T> A (p.Phe1074Leu)single nucleotide variantLikely pathogenicrs186045772GRCh37Chr 7, 117251717: 117251717
192CFTRNM_000492.3(CFTR): c.3230T> C (p.Leu1077Pro)single nucleotide variantPathogenicrs139304906GRCh37Chr 7, 117251725: 117251725
193CFTRNM_000492.3(CFTR): c.325_327delTATinsG (p.Tyr109Glyfs)indelPathogenicrs121908798GRCh37Chr 7, 117171004: 117171006
194CFTRNM_000492.3(CFTR): c.3293G> A (p.Trp1098Ter)single nucleotide variantPathogenicrs397508532GRCh37Chr 7, 117251788: 117251788
195CFTRNM_000492.3(CFTR): c.3304A> T (p.Arg1102Ter)single nucleotide variantPathogenicrs397508536GRCh37Chr 7, 117251799: 117251799
196CFTRNM_000492.3(CFTR): c.3310G> T (p.Glu1104Ter)single nucleotide variantPathogenicrs397508538GRCh37Chr 7, 117251805: 117251805
197CFTRNM_000492.3(CFTR): c.3605delA (p.Asp1202Alafs)deletionPathogenicrs397508587GRCh37Chr 7, 117267712: 117267712
198CFTRNM_000492.3(CFTR): c.3612G> A (p.Trp1204Ter)single nucleotide variantPathogenicrs121908765GRCh37Chr 7, 117267719: 117267719
199CFTRNM_000492.3(CFTR): c.3718-3T> Gsingle nucleotide variantPathogenicrs397508596GRCh37Chr 7, 117282489: 117282489
200CFTRNM_000492.3(CFTR): c.3731G> A (p.Gly1244Glu)single nucleotide variantPathogenic, drug responsers267606723GRCh37Chr 7, 117282505: 117282505
201CFTRNM_000492.3(CFTR): c.3761T> G (p.Leu1254Ter)single nucleotide variantPathogenicrs397508604GRCh37Chr 7, 117282535: 117282535
202CFTRNM_000492.3(CFTR): c.3883_3886delATTT (p.Ile1295Phefs)deletionPathogenicrs387906373GRCh37Chr 7, 117292905: 117292908
203CFTRNM_000492.3(CFTR): c.3883delA (p.Ile1295Phefs)deletionPathogenicrs397508630GRCh37Chr 7, 117292905: 117292905
204CFTRNM_000492.3(CFTR): c.3889dupT (p.Ser1297Phefs)duplicationPathogenicrs121908808GRCh37Chr 7, 117292911: 117292911
205CFTRNM_000492.3(CFTR): c.3908delA (p.Asn1303Thrfs)deletionPathogenicrs397508637GRCh37Chr 7, 117292930: 117292930
206CFTRNM_000492.3(CFTR): c.4077_4080delTGTTinsAA (p.Val1360Thrfs)indelPathogenicrs397508668GRCh37Chr 7, 117304855: 117304858
207CFTRNM_000492.3(CFTR): c.4086dupT (p.Lys1363Terfs)duplicationPathogenicrs397508669GRCh37Chr 7, 117304864: 117304864
208CFTRNM_000492.3(CFTR): c.409delC (p.Leu137Serfs)deletionPathogenicrs397508672GRCh37Chr 7, 117171088: 117171088
209CFTRNM_000492.3(CFTR): c.4111G> T (p.Glu1371Ter)single nucleotide variantPathogenicrs397508675GRCh37Chr 7, 117304889: 117304889
210CFTRNM_000492.3(CFTR): c.4144C> T (p.Gln1382Ter)single nucleotide variantPathogenicrs397508684GRCh37Chr 7, 117305520: 117305520
211CFTRNM_000492.3(CFTR): c.4147dupA (p.Ile1383Asnfs)duplicationPathogenicrs397508685GRCh37Chr 7, 117305523: 117305523
212CFTRNM_000492.3(CFTR): c.4196_4197delTC (p.Cys1400Terfs)deletionPathogenicrs397508693GRCh37Chr 7, 117305572: 117305573
213CFTRNM_000492.3(CFTR): c.4231C> T (p.Gln1411Ter)single nucleotide variantPathogenicrs397508701GRCh37Chr 7, 117305607: 117305607
214CFTRNM_000492.3(CFTR): c.4234C> T (p.Gln1412Ter)single nucleotide variantPathogenicrs397508702GRCh37Chr 7, 117305610: 117305610
215CFTRNM_000492.3(CFTR): c.4242+1G> Tsingle nucleotide variantPathogenicrs372227120GRCh37Chr 7, 117305619: 117305619
216CFTRNM_000492.3(CFTR): c.4251delA (p.Glu1418Argfs)deletionPathogenicrs397508706GRCh37Chr 7, 117306970: 117306970
217CFTRNM_000492.3(CFTR): c.4296_4297insGA (p.Ser1435Glyfs)insertionPathogenicrs397508709GRCh37Chr 7, 117307015: 117307016
218CFTRNM_000492.3(CFTR): c.4426C> T (p.Gln1476Ter)single nucleotide variantPathogenicrs374705585GRCh37Chr 7, 117307145: 117307145
219CFTRNM_000492.3(CFTR): c.442delA (p.Ile148Leufs)deletionPathogenicrs121908770GRCh37Chr 7, 117171121: 117171121
220CFTRNM_000492.3(CFTR): c.49_50dupTT (p.Trp19Alafs)duplicationPathogenicrs397508739GRCh37Chr 7, 117120197: 117120198
221CFTRNM_000492.3(CFTR): c.50delT (p.Phe17Serfs)deletionPathogenicrs397508742GRCh37Chr 7, 117120198: 117120198
222CFTRNM_000492.3(CFTR): c.53+1G> Tsingle nucleotide variantPathogenicrs397508746GRCh37Chr 7, 117120202: 117120202
223CFTRNM_000492.3(CFTR): c.531delT (p.Ile177Metfs)deletionPathogenicrs121908771GRCh37Chr 7, 117174371: 117174371
224CFTRNM_000492.3(CFTR): c.543_546delTAGT (p.Leu183Phefs)deletionPathogenicrs397508750GRCh37Chr 7, 117174383: 117174386
225CFTRNM_000492.3(CFTR): c.577G> T (p.Glu193Ter)single nucleotide variantPathogenicrs397508759GRCh37Chr 7, 117174417: 117174417
226CFTRNM_000492.3(CFTR): c.579+3A> Gsingle nucleotide variantPathogenicrs397508761GRCh37Chr 7, 117174422: 117174422
227CFTRNM_000492.3(CFTR): c.579+5G> Asingle nucleotide variantPathogenicrs78440224GRCh37Chr 7, 117174424: 117174424
228CFTRNM_000492.3(CFTR): c.580-1G> Tsingle nucleotide variantPathogenicrs121908793GRCh37Chr 7, 117175301: 117175301
229CFTRNM_000492.3(CFTR): c.595C> T (p.His199Tyr)single nucleotide variantPathogenicrs121908802GRCh37Chr 7, 117175317: 117175317
230CFTRNM_000492.3(CFTR): c.613C> T (p.Pro205Ser)single nucleotide variantPathogenicrs121908803GRCh37Chr 7, 117175335: 117175335
231CFTRNM_000492.3(CFTR): c.658C> T (p.Gln220Ter)single nucleotide variantPathogenicrs397508778GRCh37Chr 7, 117175380: 117175380
232CFTRNM_000492.3(CFTR): c.680T> G (p.Leu227Arg)single nucleotide variantPathogenicrs397508782GRCh37Chr 7, 117175402: 117175402
233CFTRNM_000492.3(CFTR): c.743+1G> Csingle nucleotide variantLikely pathogenicrs397508791GRCh37Chr 7, 117175466: 117175466
234CFTRNM_000492.3(CFTR): c.79G> T (p.Gly27Ter)single nucleotide variantPathogenicrs397508796GRCh37Chr 7, 117144332: 117144332
235CFTRNM_000492.3(CFTR): c.828C> A (p.Cys276Ter)single nucleotide variantPathogenicrs397508799GRCh37Chr 7, 117176686: 117176686
236CFTRNM_000492.3(CFTR): c.861_865delCTTAA (p.Asn287Lysfs)deletionPathogenicrs397508805GRCh37Chr 7, 117176719: 117176723
237CFTRNM_000492.3(CFTR): c.987delA (p.Gly330Glufs)deletionPathogenicrs397508824GRCh37Chr 7, 117180271: 117180271
238CFTRNM_000492.3(CFTR): c.1647T> G (p.Ser549Arg)single nucleotide variantPathogenic, drug responsers121909005GRCh37Chr 7, 117227855: 117227855
239CFTRNM_000492.3: c.1679+1.6kbA> Gundetermined variantPathogenic
240CFTRNM_000492.3(CFTR): c.2453delT (p.Leu818Trpfs)deletionPathogenicrs397515498GRCh37Chr 7, 117232674: 117232674
241CFTRNM_000492.3(CFTR): c.3964-78_4242+577deldeletionPathogenicGRCh38Chr 7, 117664610: 117666141
242CFTRNG_016465.4: g.37530_58609deldeletionPathogenic
243CFTRNM_000492.3(CFTR): c.1521_1523delCTT (p.Phe508delPhe)deletionPathogenic, drug responsers113993960GRCh37Chr 7, 117199646: 117199648
244CFTRNM_000492.3(CFTR): c.1519_1521delATC (p.Ile507del)deletionPathogenicrs121908745GRCh37Chr 7, 117199644: 117199646
245CFTRNM_000492.3(CFTR): c.1477C> T (p.Gln493Ter)single nucleotide variantPathogenicrs77101217GRCh37Chr 7, 117199602: 117199602
246CFTRNM_000492.3(CFTR): c.328G> C (p.Asp110His)single nucleotide variantPathogenicrs113993958GRCh37Chr 7, 117171007: 117171007
247CFTRNM_000492.3(CFTR): c.350G> A (p.Arg117His)single nucleotide variantPathogenicrs78655421GRCh37Chr 7, 117171029: 117171029
248CFTRNM_000492.3(CFTR): c.1040G> C (p.Arg347Pro)single nucleotide variantPathogenicrs77932196GRCh37Chr 7, 117180324: 117180324
249CFTRNM_000492.3(CFTR): c.1364C> A (p.Ala455Glu)single nucleotide variantPathogenicrs74551128GRCh37Chr 7, 117188849: 117188849
250CFTRNM_000492.3(CFTR): c.1585-1G> Asingle nucleotide variantPathogenicrs76713772GRCh37Chr 7, 117227792: 117227792
251CFTRNM_000492.3(CFTR): c.1679G> C (p.Arg560Thr)single nucleotide variantPathogenicrs80055610GRCh37Chr 7, 117227887: 117227887
252CFTRNM_000492.3(CFTR): c.1687T> A (p.Tyr563Asn)single nucleotide variantPathogenicrs121909006GRCh37Chr 7, 117230414: 117230414
253CFTRNM_000492.3(CFTR): c.1624G> T (p.Gly542Ter)single nucleotide variantPathogenicrs113993959GRCh37Chr 7, 117227832: 117227832
254CFTRNM_000492.3(CFTR): c.1646G> A (p.Ser549Asn)single nucleotide variantPathogenic, drug responsers121908755GRCh37Chr 7, 117227854: 117227854
255CFTRNM_000492.3(CFTR): c.1646G> T (p.Ser549Ile)single nucleotide variantPathogenicrs121908755GRCh37Chr 7, 117227854: 117227854
256CFTRNM_000492.3(CFTR): c.1721C> A (p.Pro574His)single nucleotide variantPathogenicrs121908758GRCh37Chr 7, 117230448: 117230448
257CFTRNM_000492.3(CFTR): c.1652G> A (p.Gly551Asp)single nucleotide variantPathogenic, drug responsers75527207GRCh37Chr 7, 117227860: 117227860
258CFTRNM_000492.3(CFTR): c.1657C> T (p.Arg553Ter)single nucleotide variantPathogenicrs74597325GRCh37Chr 7, 117227865: 117227865
259CFTRNM_000492.3(CFTR): c.1675G> A (p.Ala559Thr)single nucleotide variantPathogenicrs75549581GRCh37Chr 7, 117227883: 117227883
260CFTRNM_000492.3(CFTR): c.3659delC (p.Thr1220Lysfs)deletionPathogenicrs121908811GRCh37Chr 7, 117267766: 117267766
261CFTRNM_000492.3(CFTR): c.3764C> A (p.Ser1255Ter)single nucleotide variantPathogenicrs76649725GRCh37Chr 7, 117282538: 117282538
262CFTRNM_000492.3(CFTR): c.2538G> A (p.Trp846Ter)single nucleotide variantPathogenicrs267606722GRCh37Chr 7, 117235031: 117235031
263CFTRNM_000492.3(CFTR): c.2738A> G (p.Tyr913Cys)single nucleotide variantPathogenicrs121909008GRCh37Chr 7, 117243666: 117243666
264CFTRNM_000492.3(CFTR): c.3846G> A (p.Trp1282Ter)single nucleotide variantPathogenicrs77010898GRCh37Chr 7, 117282620: 117282620
265CFTRNM_000492.3(CFTR): c.1373G> T (p.Gly458Val)single nucleotide variantPathogenicrs121909009GRCh37Chr 7, 117188858: 117188858
266CFTRNM_000492.3(CFTR): c.3947G> A (p.Trp1316Ter)single nucleotide variantPathogenicrs121909010GRCh37Chr 7, 117292969: 117292969
267CFTRNM_000492.3(CFTR): c.1021_1022dupTC (p.Phe342Hisfs)duplicationPathogenicrs387906360GRCh37Chr 7, 117180305: 117180306
268CFTRNM_000492.3(CFTR): c.1081delT (p.Trp361Glyfs)deletionPathogenicrs387906361GRCh37Chr 7, 117180365: 117180365
269CFTRNM_000492.3(CFTR): c.3909C> G (p.Asn1303Lys)single nucleotide variantPathogenicrs80034486GRCh37Chr 7, 117292931: 117292931
270CFTRNM_000492.3(CFTR): c.3484C> T (p.Arg1162Ter)single nucleotide variantPathogenicrs74767530GRCh37Chr 7, 117267591: 117267591
271CFTRNM_000492.3(CFTR): c.3717+4A> Gsingle nucleotide variantPathogenicrs387906362GRCh37Chr 7, 117267828: 117267828
272CFTRNM_000492.3(CFTR): c.1000C> T (p.Arg334Trp)single nucleotide variantPathogenicrs121909011GRCh37Chr 7, 117180284: 117180284
273CFTRNM_000492.3(CFTR): c.1545_1546delTA (p.Tyr515Terfs)deletionPathogenicrs121908776GRCh37Chr 7, 117199670: 117199671
274CFTRNM_000492.3(CFTR): c.2551C> T (p.Arg851Ter)single nucleotide variantPathogenicrs121909012GRCh37Chr 7, 117235044: 117235044
275CFTRNM_000492.3(CFTR): c.1651G> A (p.Gly551Ser)single nucleotide variantPathogenic, drug responsers121909013GRCh37Chr 7, 117227859: 117227859
276CFTRNM_000492.3(CFTR): c.254G> A (p.Gly85Glu)single nucleotide variantPathogenicrs75961395GRCh37Chr 7, 117149177: 117149177
277CFTRNM_000492.3(CFTR): c.3472C> T (p.Arg1158Ter)single nucleotide variantPathogenicrs79850223GRCh37Chr 7, 117267579: 117267579
278CFTRNM_000492.3(CFTR): c.720_741del22 (p.Gly241Glufs)deletionPathogenicrs121908804GRCh37Chr 7, 117175442: 117175463
279CFTRNM_000492.3(CFTR): c.424delA (p.Ile142Phefs)deletionPathogenicrs387906363GRCh37Chr 7, 117171103: 117171103
280CFTRNM_000492.3(CFTR): c.429delT (p.Phe143Leufs)deletionPathogenicrs387906364GRCh37Chr 7, 117171108: 117171108
281CFTRNM_000492.3(CFTR): c.2737_2738insG (p.Tyr913Terfs)insertionPathogenicrs121908788GRCh37Chr 7, 117243665: 117243666
282CFTRNM_000492.3(CFTR): c.1558G> T (p.Val520Phe)single nucleotide variantPathogenicrs77646904GRCh37Chr 7, 117199683: 117199683
283CFTRNM_000492.3(CFTR): c.1572C> A (p.Cys524Ter)single nucleotide variantPathogenicrs121908754GRCh37Chr 7, 117199697: 117199697
284CFTRNM_000492.3(CFTR): c.3873G> C (p.Gln1291His)single nucleotide variantPathogenicrs121909015GRCh37Chr 7, 117282647: 117282647
285CFTRNM_000492.3(CFTR): c.933C> G (p.Phe311Leu)single nucleotide variantPathogenicrs121909016GRCh37Chr 7, 117180217: 117180217
286CFTRNM_000492.3(CFTR): c.1093_1094delCT (p.Leu365Trpfs)deletionPathogenicrs387906365GRCh37Chr 7, 117180377: 117180378
287CFTRNM_000492.3(CFTR): c.1475C> T (p.Ser492Phe)single nucleotide variantPathogenicrs121909017GRCh37Chr 7, 117199600: 117199600
288CFTRNM_000492.3(CFTR): c.1679G> A (p.Arg560Lys)single nucleotide variantPathogenicrs80055610GRCh37Chr 7, 117227887: 117227887
289CFTRNM_000492.3(CFTR): c.2479G> T (p.Glu827Ter)single nucleotide variantPathogenicrs121909018GRCh37Chr 7, 117232700: 117232700
290CFTRNM_000492.3(CFTR): c.3197G> A (p.Arg1066His)single nucleotide variantPathogenicrs121909019GRCh37Chr 7, 117251692: 117251692
291CFTRNM_000492.3(CFTR): c.3873+1G> Asingle nucleotide variantPathogenicrs143570767GRCh37Chr 7, 117282648: 117282648
292CFTRNM_000492.3(CFTR): c.3184_3188dupCTATG (p.Trp1063Cysfs)duplicationPathogenicrs387906366GRCh37Chr 7, 117251679: 117251683
293CFTRNM_000492.3(CFTR): c.3196C> T (p.Arg1066Cys)single nucleotide variantPathogenicrs78194216GRCh37Chr 7, 117251691: 117251691
294CFTRNM_000492.3(CFTR): c.948delT (p.Phe316Leufs)deletionPathogenicrs121908744GRCh37Chr 7, 117180232: 117180232
295CFTRNM_000492.3(CFTR): c.1727G> C (p.Gly576Ala)single nucleotide variantPathogenicrs1800098GRCh37Chr 7, 117230454: 117230454
296CFTRNM_000492.3: c.3718-2477C> Tsingle nucleotide variantPathogenicrs75039782GRCh37Chr 7, 117280015: 117280015
297CFTRNM_000492.3(CFTR): c.3848G> T (p.Arg1283Met)single nucleotide variantPathogenicrs77902683GRCh37Chr 7, 117282622: 117282622
298CFTRNM_000492.3(CFTR): c.1766+1G> Asingle nucleotide variantPathogenicrs121908748GRCh37Chr 7, 117230494: 117230494
299CFTRNM_000492.3(CFTR): c.744-14_744-3delTGATTGATTTACdeletionPathogenicrs387906367GRCh37Chr 7, 117176588: 117176599
300CFTRNM_000492.3(CFTR): c.1040G> T (p.Arg347Leu)single nucleotide variantPathogenicrs77932196GRCh37Chr 7, 117180324: 117180324
301CFTRNM_000492.3(CFTR): c.1046C> T (p.Ala349Val)single nucleotide variantPathogenicrs121909021GRCh37Chr 7, 117180330: 117180330
302CFTRNM_000492.3(CFTR): c.1601C> A (p.Ala534Glu)single nucleotide variantPathogenicrs387906368GRCh38Chr 7, 117587755: 117587755
303CFTRNM_000492.3(CFTR): c.2146A> T (p.Lys716Ter)single nucleotide variantPathogenicrs121909023GRCh37Chr 7, 117232367: 117232367
304CFTRNM_000492.3(CFTR): c.2490+1G> Asingle nucleotide variantPathogenicrs141158996GRCh37Chr 7, 117232712: 117232712
305CFTRNM_000492.3(CFTR): c.3712C> T (p.Gln1238Ter)single nucleotide variantPathogenicrs121908766GRCh37Chr 7, 117267819: 117267819
306CFTRNM_000492.3(CFTR): c.3718-1G> Asingle nucleotide variantPathogenicrs387906369GRCh37Chr 7, 117282491: 117282491
307CFTRNM_000492.3(CFTR): c.3767dupC (p.Leu1258Phefs)duplicationPathogenicrs387906370GRCh37Chr 7, 117282541: 117282541
308CFTRNM_000492.3(CFTR): c.171G> A (p.Trp57Ter)single nucleotide variantPathogenicrs121909025GRCh37Chr 7, 117149094: 117149094
309CFTRNM_000492.3(CFTR): c.3937C> T (p.Gln1313Ter)single nucleotide variantPathogenicrs121909026GRCh37Chr 7, 117292959: 117292959
310CFTRNM_000492.3(CFTR): c.274G> A (p.Glu92Lys)single nucleotide variantPathogenicrs121908751GRCh37Chr 7, 117170953: 117170953
311CFTRNM_000492.3(CFTR): c.1040G> A (p.Arg347His)single nucleotide variantPathogenicrs77932196GRCh37Chr 7, 117180324: 117180324
312CFTRNM_000492.3(CFTR): c.271G> A (p.Gly91Arg)single nucleotide variantPathogenicrs121908750GRCh37Chr 7, 117149194: 117149194
313CFTRNM_000492.3(CFTR): c.3857T> C (p.Phe1286Ser)single nucleotide variantPathogenicrs121909028GRCh37Chr 7, 117282631: 117282631
314CFTRNM_000492.3(CFTR): c.2175dupA (p.Glu726Argfs)duplicationPathogenicrs121908787GRCh37Chr 7, 117232396: 117232396
315CFTRNM_000492.3(CFTR): c.274G> T (p.Glu92Ter)single nucleotide variantPathogenicrs121908751GRCh37Chr 7, 117170953: 117170953
316CFTRNM_000492.3(CFTR): c.1438G> T (p.Gly480Cys)single nucleotide variantPathogenicrs79282516GRCh37Chr 7, 117199563: 117199563
317CFTRNM_000492.3(CFTR): c.459_476del18 (p.Ala155_Ile160del)deletionPathogenicrs387906371GRCh37Chr 7, 117171138: 117171155
318CFTRNM_000492.3(CFTR): c.617T> G (p.Leu206Trp)single nucleotide variantPathogenicrs121908752GRCh37Chr 7, 117175339: 117175339
319CFTRCFTR, GLN524HISsingle nucleotide variantPathogenic
320CFTRNM_000492.3(CFTR): c.3763T> C (p.Ser1255Pro)single nucleotide variantPathogenic, drug responsers121909041GRCh37Chr 7, 117282537: 117282537
321CFTRNM_000492.3(CFTR): c.1013C> T (p.Thr338Ile)single nucleotide variantPathogenicrs77409459GRCh37Chr 7, 117180297: 117180297
322CFTRNM_000492.3(CFTR): c.3266G> A (p.Trp1089Ter)single nucleotide variantPathogenicrs78802634GRCh37Chr 7, 117251761: 117251761
323CFTRNM_000492.3(CFTR): c.326A> G (p.Tyr109Cys)single nucleotide variantPathogenicrs121909031GRCh37Chr 7, 117171005: 117171005
324CFTRNM_000492.3(CFTR): c.1055G> A (p.Arg352Gln)single nucleotide variantPathogenicrs121908753GRCh37Chr 7, 117180339: 117180339
325CFTRNM_000492.3(CFTR): c.273+4A> Gsingle nucleotide variantPathogenicrs387906374GRCh37Chr 7, 117149200: 117149200
326CFTRNM_000492.3(CFTR): c.1654C> T (p.Gln552Ter)single nucleotide variantPathogenicrs76554633GRCh37Chr 7, 117227862: 117227862
327CFTRNM_000492.3(CFTR): c.1943A> T (p.Asp648Val)single nucleotide variantPathogenicrs121909033GRCh37Chr 7, 117232164: 117232164
328CFTRNM_000492.3(CFTR): c.2128A> T (p.Lys710Ter)single nucleotide variantPathogenicrs75115087GRCh37Chr 7, 117232349: 117232349
329CFTRNM_000492.3(CFTR): c.2668C> T (p.Gln890Ter)single nucleotide variantPathogenicrs79633941GRCh37Chr 7, 117243596: 117243596
330CFTRNM_000492.3(CFTR): c.805_806delAT (p.Ile269Profs)deletionPathogenicrs121908773GRCh37Chr 7, 117176663: 117176664
331CFTRNM_000492.3(CFTR): c.2845C> T (p.His949Tyr)single nucleotide variantPathogenicrs121909035GRCh37Chr 7, 117243773: 117243773
332CFTRNM_000492.3(CFTR): c.3194T> C (p.Leu1065Pro)single nucleotide variantPathogenicrs121909036GRCh37Chr 7, 117251689: 117251689
333CFTRNM_000492.3(CFTR): c.3212A> C (p.Gln1071Pro)single nucleotide variantPathogenicrs121909037GRCh37Chr 7, 117251707: 117251707
334CFTRNM_000492.3(CFTR): c.3254A> G (p.His1085Arg)single nucleotide variantLikely pathogenic, Pathogenicrs79635528GRCh37Chr 7, 117251749: 117251749
335CFTRNM_000492.3(CFTR): c.3276C> G (p.Tyr1092Ter)single nucleotide variantPathogenicrs121908761GRCh37Chr 7, 117251771: 117251771
336CFTRNM_000492.3(CFTR): c.3611G> A (p.Trp1204Ter)single nucleotide variantPathogenicrs121908764GRCh37Chr 7, 117267718: 117267718
337CFTRNM_000492.3(CFTR): c.1083delG (p.Trp361Cysfs)deletionPathogenicrs387906375GRCh37Chr 7, 117180367: 117180367
338CFTRNM_000492.3(CFTR): c.3659C> T (p.Thr1220Ile)single nucleotide variantPathogenicrs1800123GRCh37Chr 7, 117267766: 117267766
339CFTRNM_000492.3(CFTR): c.3700A> G (p.Ile1234Val)single nucleotide variantPathogenicrs75389940GRCh37Chr 7, 117267807: 117267807
340CFTRNM_000492.3(CFTR): c.3746G> A (p.Gly1249Glu)single nucleotide variantPathogenicrs121909040GRCh37Chr 7, 117282520: 117282520
341CFTRNM_000492.3(CFTR): c.3752G> A (p.Ser1251Asn)single nucleotide variantPathogenic, drug responsers74503330GRCh37Chr 7, 117282526: 117282526
342CFTRNM_000492.3(CFTR): c.3907A> C (p.Asn1303His)single nucleotide variantPathogenicrs121909042GRCh37Chr 7, 117292929: 117292929
343CFTRNM_000492.3(CFTR): c.1477_1478delCA (p.Gln493Valfs)deletionPathogenicrs121908775GRCh37Chr 7, 117199602: 117199603
344CFTRNM_000492.3(CFTR): c.2291delG (p.Arg764Glnfs)deletionPathogenicrs387906376GRCh37Chr 7, 117232512: 117232512
345CFTRNM_000492.3(CFTR): c.3161delA (p.His1054Leufs)deletionPathogenicrs387906377GRCh37Chr 7, 117251656: 117251656
346CFTRNM_000492.3(CFTR): c.3532_3535dupTCAA (p.Thr1179Ilefs)duplicationPathogenicrs387906378GRCh37Chr 7, 117267639: 117267642
347CFTRNM_000492.3(CFTR): c.4364C> G (p.Ser1455Ter)single nucleotide variantPathogenicrs121909043GRCh37Chr 7, 117307083: 117307083
348CFTRNM_000492.3(CFTR): c.2988+1G> Asingle nucleotide variantPathogenicrs75096551GRCh37Chr 7, 117246808: 117246808
349CFTRNM_000492.3(CFTR): c.1658G> A (p.Arg553Gln)single nucleotide variantPathogenicrs121909044GRCh37Chr 7, 117227866: 117227866
350CFTRNM_000492.3(CFTR): c.-102A=single nucleotide variantPathogenicGRCh37Chr 7, 117120047: 117120047
351CFTRNG_016465.3: g.(37526_37529)_(58606_58609)deletionPathogenicGRCh37Chr 7, 117138363: 117159446
352CFTRNM_000492.3(CFTR): c.3469-20T> Csingle nucleotide variantPathogenicrs373002889GRCh37Chr 7, 117267556: 117267556
353CFTRNM_000492.3(CFTR): c.2991G> C (p.Leu997Phe)single nucleotide variantPathogenic, risk factorrs1800111GRCh37Chr 7, 117250575: 117250575
354CFTRNM_000492.3(CFTR): c.3492dupT (p.Lys1165Terfs)duplicationPathogenicrs387906379GRCh37Chr 7, 117267599: 117267599
355CFTRNM_000492.3(CFTR): c.3744delA (p.Lys1250Argfs)deletionPathogenicrs121908784GRCh37Chr 7, 117282518: 117282518
356CFTRNM_000492.3(CFTR): c.262_263delTT (p.Leu88Ilefs)deletionPathogenicrs121908769GRCh37Chr 7, 117149185: 117149186
357CFTRCFTR, HIS1282TERundetermined variantPathogenic
358CFTRCFTR, ALA445GLUundetermined variantPathogenic
359CFTRNM_000492.3(CFTR): c.19G> T (p.Glu7Ter)single nucleotide variantPathogenicrs121909045GRCh37Chr 7, 117120167: 117120167
360CFTRNM_000492.3(CFTR): c.860dupA (p.Asn287Lysfs)duplicationPathogenicrs387906380GRCh37Chr 7, 117176718: 117176718
361CFTRNM_000492.3(CFTR): c.4056G> C (p.Gln1352His)single nucleotide variantPathogenicrs113857788GRCh37Chr 7, 117304834: 117304834
362CFTRNM_000492.3(CFTR): c.650A> G (p.Glu217Gly)single nucleotide variantPathogenicrs121909046GRCh37Chr 7, 117175372: 117175372
363CFTRNM_000492.3(CFTR): c.1682C> A (p.Ala561Glu)single nucleotide variantPathogenicrs121909047GRCh37Chr 7, 117230409: 117230409

Copy number variations for Cystic Fibrosis from CNVD:

6
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
12187577116907252117095954DeletionCFTRCystic fibrosis
22187587116907252117095954DeletionCFTRCystic fibrosis
32337648127300000131500000Copy numberL1Cystic fibrosis

Expression for genes affiliated with Cystic Fibrosis

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LifeMap Discovery
Genes differentially expressed in tissues of Cystic Fibrosis patients vs. healthy controls: 33
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1ALDOBaldolase B, fructose-bisphosphateEpithelial Cells+3.080.000

Search GEO for disease gene expression data for Cystic Fibrosis.

Pathways for genes affiliated with Cystic Fibrosis

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Pathways related to Cystic Fibrosis according to GeneCards Suite gene sharing:

(show all 13)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
10.5CFTR, CXCL8, TGFB1
210.5CXCL8, FCGR2A, TGFB1
310.4CLCA1, CLCA2, CLCA4
4
Show member pathways
10.4CLCA1, CLCA2, CLCA4
510.4CFTR, CLCA1, CLCA2, CLCA4
6
Show member pathways
10.4SCNN1A, SCNN1B, SCNN1G
710.4SCNN1A, SCNN1B, SCNN1G
810.4SCNN1A, SCNN1B, SCNN1G
910.4CFTR, SCNN1A, SCNN1B, SCNN1G
1010.4CFTR, CLCA2, SCNN1A, SCNN1B, SCNN1G, SLC9A3R1
11
Show member pathways
10.4CLCA1, CLCA2, CLCA4, SCNN1A, SCNN1B, SCNN1G
12
Show member pathways
10.4CFTR, CLCA1, CLCA2, CLCA4, SCNN1A, SCNN1B
13
Show member pathways
10.4ABCC10, CFTR, CLCA1, CLCA2, CLCA4, SCNN1A

GO Terms for genes affiliated with Cystic Fibrosis

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Cellular components related to Cystic Fibrosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1sodium channel complexGO:003470611.2SCNN1A, SCNN1B, SCNN1G
2secretory granuleGO:003014111.1CLCA1, ELANE, STX1A, TGFB1
3microvillusGO:000590211.0CLCA1, SLC9A3R1, TGFB1
4sperm midpieceGO:009722511.0DEFB1, SLC9A3R1
5extracellular spaceGO:000561510.6CLCA1, CXCL8, DEFB1, ELANE, S100A8, S100A9
6extracellular regionGO:000557610.6CLCA2, CXCL8, DEFB1, DNASE1, ELANE, S100A8
7extracellular exosomeGO:007006210.5CFTR, CLCA4, DEFB1, DNASE1, ELANE, FCGR2A
8apical plasma membraneGO:001632410.4CFTR, CLCA4, SCNN1A, SCNN1B, SCNN1G, SLC9A3R1
9plasma membraneGO:000588610.3ABCC10, CFTR, CLCA1, CLCA2, CLCA4, FCGR2A

Biological processes related to Cystic Fibrosis according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of peptide secretionGO:000279311.1S100A8, S100A9
2peptidyl-cysteine S-nitrosylationGO:001811911.1S100A8, S100A9
3chemokine productionGO:003260211.1S100A8, S100A9
4neutrophil aggregationGO:007048811.1S100A8, S100A9
5sequestering of zinc ionGO:003211911.1S100A8, S100A9
6multicellular organismal water homeostasisGO:005089111.0SCNN1A, SCNN1B, SCNN1G
7sensory perception of tasteGO:005090911.0SCNN1A, SCNN1B, SCNN1G
8regulation of cytoskeleton organizationGO:005149311.0S100A8, S100A9
9chloride transmembrane transportGO:190247610.9CFTR, CLCA1, CLCA2, CLCA4
10leukocyte migration involved in inflammatory responseGO:000252310.9ELANE, S100A8, S100A9
11sodium ion transmembrane transportGO:003572510.9SCNN1A, SCNN1B, SCNN1G
12neutrophil chemotaxisGO:003059310.9CXCL8, S100A8, S100A9
13sodium ion homeostasisGO:005507810.9SCNN1A, SCNN1B, SCNN1G
14acute inflammatory responseGO:000252610.8DEFB1, S100A8
15defense response to bacteriumGO:004274210.7DEFB1, ELANE, S100A8, S100A9
16defense response to fungusGO:005083210.6ELANE, S100A8, S100A9
17transportGO:000681010.5CFTR, CLCA1, CLCA2, CLCA4
18astrocyte developmentGO:001400210.5S100A8, S100A9
19ion transmembrane transportGO:003422010.3CLCA1, CLCA2, CLCA4, SCNN1A, SCNN1B, SCNN1G
20positive regulation of intrinsic apoptotic signaling pathwayGO:200124410.1S100A8, S100A9, SLC9A3R1

Molecular functions related to Cystic Fibrosis according to GeneCards Suite gene sharing:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1arachidonic acid bindingGO:005054411.0S100A8, S100A9
2RAGE receptor bindingGO:005078611.0S100A8, S100A9
3chloride channel inhibitor activityGO:001986910.9CFTR, STX1A
4anion transmembrane-transporting ATPase activityGO:004322510.9ABCC10, CFTR
5ligand-gated sodium channel activityGO:001528010.9SCNN1A, SCNN1B, SCNN1G
6chloride channel regulator activityGO:001708110.9CFTR, SLC9A3R1
7intracellular calcium activated chloride channel activityGO:000522910.8CLCA1, CLCA2, CLCA4
8metalloendopeptidase activityGO:000422210.8CLCA1, CLCA2, CLCA4
9chloride channel activityGO:000525410.7CFTR, CLCA1, CLCA2, CLCA4
10Toll-like receptor 4 bindingGO:003566210.5S100A8, S100A9
11WW domain bindingGO:005069910.4SCNN1A, SCNN1B, SCNN1G
12protein N-terminus bindingGO:004748510.2DCTN4, STX1A, TGFB1

Sources for Cystic Fibrosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet