MCID: CYS002
MIFTS: 39

Cystic Lymphangioma malady

Rare diseases, Cardiovascular diseases, Skin diseases, Fetal diseases, Cancer diseases, Immune diseases categories

Aliases & Classifications for Cystic Lymphangioma

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Sources:
10Disease Ontology, 45NIH Rare Diseases, 12DISEASES, 51Orphanet, 65UMLS, 36MeSH, 59SNOMED-CT, 42NCIt, 28ICD10 via Orphanet
See all sources

Aliases & Descriptions for Cystic Lymphangioma:

Name: Cystic Lymphangioma 10 12
Cystic Hygroma 10 45 51
 
Lymphangioma, Cystic 65 36


Classifications:



Characteristics (Orphanet epidemiological data):

51
cystic hygroma:
Inheritance: Not applicable; Age of onset: Infancy,Neonatal


External Ids:

Disease Ontology10 DOID:3081
MeSH36 D018191
NCIt42 C3724
Orphanet51 79486
ICD10 via Orphanet28 D18.1

Summaries for Cystic Lymphangioma

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NIH Rare Diseases:45 Cystic hygroma is a birth defect that causes a soft mass, often in the head and neck area. it may be discovered in a fetus during a pregnancy ultrasound, in a newborn, or it may not become evident until later in life. when a cystic hygroma is identified in a fetus, parents are counseled regarding their baby's risk for having a chromosome problem or other birth defect, and are offered additional testing options such as special ultrasound tests or amniocentesis. cystic hygromas in infants, children, or adults may enlarge or become infected, and may require surgery or other therapy to remove or shrink the mass. last updated: 3/4/2010

MalaCards based summary: Cystic Lymphangioma, also known as cystic hygroma, is related to multiple pterygium syndrome, lethal type and lymphangioma. An important gene associated with Cystic Lymphangioma is IFNG (Interferon, Gamma), and among its related pathways are Glucocorticoid receptor regulatory network and . Affiliated tissues include testes, pancreas and colon, and related mouse phenotype respiratory system.

Related Diseases for Cystic Lymphangioma

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Graphical network of the top 20 diseases related to Cystic Lymphangioma:



Diseases related to cystic lymphangioma

Symptoms for Cystic Lymphangioma

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Drugs & Therapeutics for Cystic Lymphangioma

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Drugs for Cystic Lymphangioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1PicibanilPhase 2, Phase 37
2
PancrelipaseapprovedPhase 083953608-75-6
Synonyms:
1,4-alpha-D- glucan glucanohydrolase
Creon
PA
Pancreatic alpha-amylase precursor
Pancreaze
 
Pancrelipase
Pertzye
Polocaine-mpf
Ultresa
Viokace
Zenpep
3pancreatinPhase 0839

Interventional clinical trials:

idNameStatusNCT IDPhase
1Study of Picibanil (OK432) Sclerotherapy in Children With Macrocystic Lymphatic MalformationsCompletedNCT00010452Phase 2, Phase 3
2AVAST Anomalies Vasculaires Associées au Syndrome de Turner (Vascular Abnormalities Associated With Turner Syndrome)RecruitingNCT02250456
3Needle-based Confocal Laser Endomicroscopy on Pancreatic Cystic LesionsRecruitingNCT02494388Phase 0

Search NIH Clinical Center for Cystic Lymphangioma


Cochrane evidence based reviews: Lymphangioma, Cystic

Genetic Tests for Cystic Lymphangioma

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Anatomical Context for Cystic Lymphangioma

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MalaCards organs/tissues related to Cystic Lymphangioma:

33
Testes, Pancreas, Colon, Spleen, Breast, Adrenal gland, Skin

Animal Models for Cystic Lymphangioma or affiliated genes

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MGI Mouse Phenotypes related to Cystic Lymphangioma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.4CHRNG, DOK7, IFNG, NODAL

Publications for Cystic Lymphangioma

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Articles related to Cystic Lymphangioma:

(show top 50)    (show all 376)
idTitleAuthorsYear
1
A sudden pain in the neck: an atypical presentation of cystic lymphangioma. (25795753)
2015
2
Cystic lymphangioma of the chest wall: a case report. (25606029)
2014
3
Unusual sites of cystic lymphangioma in children. (25282458)
2014
4
Cystic lymphangioma of the inguinal and scrotal regions in childhood - report of three cases. (25125963)
2014
5
Pancreatic cystic lymphangioma: diagnostic approach with MDCT and MR imaging. (25073240)
2014
6
Pericardial cystic lymphangioma. (23034994)
2013
7
An unusual cause of abdominal pain: duodenal cystic lymphangioma. (23961273)
2013
8
Differentiating a large abdominal cystic lymphangioma from multicystic mesothelioma: report of a case. (23807639)
2013
9
Intestinal obstruction complicating a mesenteric cystic lymphangioma. (22795361)
2012
10
Huge cystic lymphangioma of the pancreas mimicking pancreatic cystic neoplasm. (23197988)
2012
11
Cystic fibrosis and retroperitoneal cystic lymphangioma: a novel match. (22273284)
2012
12
A case of laparoscopic excision of a huge retroperitoneal cystic lymphangioma. (22606623)
2011
13
Cystic lymphangioma of the breast in a 6-year-old boy. (19853765)
2009
14
Retroperitoneal cystic lymphangioma: a rare presentation in childhood, treated laparoscopically. (19215217)
2009
15
Cystic lymphangioma-like adenomatoid tumor of the adrenal gland: Case presentation and review of the literature. (19851133)
2009
16
Cystic lymphangioma of the gallbladder: report of a case. (18085372)
2008
17
Lingual cystic lymphangioma in an elderly patient. (19052498)
2008
18
Cystic lymphangioma of the lesser sac presenting as acute appendicitis: A case report. (18783617)
2008
19
Cystic lymphangioma of the pancreas. (17368224)
2007
20
Cystic lymphangioma of the lesser sac. (16955953)
2006
21
Prenatal diagnosis of a fetal chest wall cystic lymphangioma using ultrasonography and MRI: a case report with literature review. (16260884)
2005
22
Image of the month. Cystic lymphangioma. (16027339)
2005
23
Mesenteric cystic lymphangioma causing intestinal occlusion in an adult patient. (14722994)
2003
24
Asymptomatic adult cystic lymphangioma of the spleen: case report and review of the literature. (12620551)
2003
25
Antepartum assessment of fetal cystic lymphangioma by magnetic resonance imaging. (12186991)
2002
26
Abdominal cystic lymphangioma: a rare cause of acute abdomen in a neonate. (11737721)
2001
27
Giant cystic lymphangioma of the stomach. (11841086)
2001
28
Huge cystic lymphangioma of the pancreas: report of a case. (11510617)
2001
29
Abdominal cystic lymphangioma in a woman at 14 weeks' gestation: case report. (11055491)
2000
30
Cystic lymphangioma in an asymptomatic newborn: an uncommon localization in the ileum. (10204513)
1999
31
Bilateral cystic lymphangioma of the adrenal gland. (10219366)
1999
32
Mediastinal cystic lymphangioma: report of two cases. (9323827)
1997
33
Progressive fetal axillary cystic lymphangioma with coexistent naevus flammeus. (9039304)
1997
34
Prenatal ultrasonographic findings of intra-abdominal cystic lymphangioma: a case report. (9142629)
1997
35
Radiology/pathology conference: mesenteric cystic lymphangioma. (8692443)
1996
36
Abdominal cystic lymphangioma in children: benign lesions that can have a proliferative course. (8861480)
1996
37
Cystic lymphangioma of the transverse colon: report of a case and review of the literature. (8832861)
1996
38
Laparoscopic resection of a retroperitoneal cystic lymphangioma. (7878511)
1994
39
Intra-abdominal cystic lymphangioma. (7927442)
1994
40
Cystic lymphangioma of the kidney: a rare cause of multiloculated renal masses. (1999216)
1991
41
Abdominal cystic lymphangioma. A case report and a review of the literature. (2180901)
1990
42
Hyponatremia resulting from loss of lymphatic fluid in an infant with cystic lymphangioma. (3723245)
1986
43
Sonographic appearance of an abdominal cystic lymphangioma. (6699930)
1984
44
Solitary cystic lymphangioma of the retroperitoneum. (904040)
1977
45
Cystic lymphangioma of the cecum with ileocecal intussusception: Case report. (1163907)
1975
46
Case report: Cystic lymphangioma of the vallecula. (1131722)
1975
47
Symptomatic venous compression from a mediastinal cystic lymphangioma. (4574172)
1973
48
Cystic lymphangioma of the parotid region. (14417246)
1960
49
Ureteral obstruction due to retroperitoneal lymphatic cyst (cystic lymphangioma). (13655395)
1959
50
CYSTIC LYMPHANGIOMA OF THE GREAT OMENTUM. (17863276)
1914

Variations for Cystic Lymphangioma

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Expression for genes affiliated with Cystic Lymphangioma

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Search GEO for disease gene expression data for Cystic Lymphangioma.

Pathways for genes affiliated with Cystic Lymphangioma

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GO Terms for genes affiliated with Cystic Lymphangioma

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Cellular components related to Cystic Lymphangioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1acetylcholine-gated channel complexGO:00058929.1CHRNA1, CHRND, CHRNG
2neuron projectionGO:00430058.9CHRNA1, CHRND, CHRNG
3postsynaptic membraneGO:00452118.7CHRNA1, CHRND, CHRNG
4synapseGO:00452028.3CHRND, CHRNG, DOK7
5cell junctionGO:00300548.1CHRNA1, CHRND, CHRNG, DOK7

Biological processes related to Cystic Lymphangioma according to GeneCards Suite gene sharing:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1neuromuscular processGO:005090510.0CHRNA1, CHRND
2skeletal muscle contractionGO:00030099.9CHRNA1, CHRND
3musculoskeletal movementGO:00508819.9CHRNA1, CHRND
4SMAD protein signal transductionGO:00603959.8AFP, NODAL
5skeletal muscle tissue growthGO:00486309.7CHRNA1, CHRND
6liver developmentGO:00018899.7AFP, NODAL
7neurological system processGO:00508779.4CHRND, CHRNG
8response to nicotineGO:00350949.1CHRNA1, CHRND, CHRNG
9cation transportGO:00068129.1CHRNA1, CHRND, CHRNG
10synaptic transmission, cholinergicGO:00072719.1CHRNA1, CHRND, CHRNG
11neuromuscular synaptic transmissionGO:00072749.1CHRNA1, CHRND, CHRNG
12cation transmembrane transportGO:00986559.1CHRNA1, CHRND, CHRNG
13ion transportGO:00068118.9CHRNA1, CHRND, CHRNG
14regulation of membrane potentialGO:00423918.7CHRNA1, CHRND, CHRNG
15synaptic transmissionGO:00072688.4CHRNA1, CHRND, CHRNG
16transportGO:00068108.3AFP, CHRNA1, CHRND, CHRNG

Molecular functions related to Cystic Lymphangioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1acetylcholine-activated cation-selective channel activityGO:00048898.7CHRNA1, CHRND, CHRNG
2acetylcholine bindingGO:00421668.7CHRNA1, CHRND, CHRNG
3extracellular ligand-gated ion channel activityGO:00052308.6CHRNA1, CHRND, CHRNG
4acetylcholine receptor activityGO:00154648.4CHRNA1, CHRND, CHRNG

Sources for Cystic Lymphangioma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet