MCID: CYS002
MIFTS: 46

Cystic Lymphangioma malady

Rare diseases, Cardiovascular diseases, Skin diseases, Fetal diseases, Cancer diseases, Immune diseases categories

Aliases & Classifications for Cystic Lymphangioma

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Sources:
9Disease Ontology, 41NIH Rare Diseases, 11DISEASES, 47Orphanet, 60UMLS, 55SNOMED-CT, 33MeSH, 38NCIt, 26ICD10 via Orphanet
See all sources

Cystic Lymphangioma, Aliases & Descriptions:

Name: Cystic Lymphangioma 9 11
Cystic Hygroma 9 41 47
 
Lymphangioma, Cystic 60


Classifications:



Characteristics (Orphanet epidemiological data):

47
cystic hygroma:
Inheritance: Not applicable; Age of onset: Infancy,Neonatal


External Ids:

Disease Ontology9 DOID:3081
MeSH33 D018191
NCIt38 C3724
Orphanet47 79486
ICD10 via Orphanet26 D18.1

Summaries for Cystic Lymphangioma

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NIH Rare Diseases:41 Cystic hygroma is a birth defect that causes a soft mass, often in the head and neck area. it may be discovered in a fetus during a pregnancy ultrasound, in a newborn, or it may not become evident until later in life. when a cystic hygroma is identified in a fetus, parents are counseled regarding their baby's risk for having a chromosome problem or other birth defect, and are offered additional testing options such as special ultrasound tests or amniocentesis. cystic hygromas in infants, children, or adults may enlarge or become infected, and may require surgery or other therapy to remove or shrink the mass. last updated: 3/4/2010

MalaCards based summary: Cystic Lymphangioma, also known as cystic hygroma, is related to multiple pterygium syndrome, lethal type and hepatitis. An important gene associated with Cystic Lymphangioma is CHRNG (cholinergic receptor, nicotinic, gamma (muscle)), and among its related pathways are Activation of Nicotinic Acetylcholine Receptors and Calcium channels. The compounds galantamine and acyclovir have been mentioned in the context of this disorder. Affiliated tissues include testes, pancreas and colon, and related mouse phenotypes are tumorigenesis and vision/eye.

Related Diseases for Cystic Lymphangioma

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Graphical network of the top 20 diseases related to Cystic Lymphangioma:



Diseases related to cystic lymphangioma

Symptoms for Cystic Lymphangioma

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Drugs & Therapeutics for Cystic Lymphangioma

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Drug clinical trials:

Search ClinicalTrials for Cystic Lymphangioma

Search NIH Clinical Center for Cystic Lymphangioma

Genetic Tests for Cystic Lymphangioma

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Anatomical Context for Cystic Lymphangioma

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MalaCards organs/tissues related to Cystic Lymphangioma:

31
Testes, Pancreas, Colon, Spleen, Breast, Adrenal gland, Skin, Tongue, Kidney, Liver, Heart, Lung, Thyroid, Testis

Animal Models for Cystic Lymphangioma or affiliated genes

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Publications for Cystic Lymphangioma

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Articles related to Cystic Lymphangioma:

(show top 50)    (show all 368)
idTitleAuthorsYear
1
A sudden pain in the neck: an atypical presentation of cystic lymphangioma. (25795753)
2015
2
Cystic lymphangioma of the chest wall: a case report. (25606029)
2014
3
Unusual sites of cystic lymphangioma in children. (25282458)
2014
4
Cystic lymphangioma of the inguinal and scrotal regions in childhood - report of three cases. (25125963)
2014
5
Pancreatic cystic lymphangioma: diagnostic approach with MDCT and MR imaging. (25073240)
2014
6
Pericardial cystic lymphangioma. (23034994)
2013
7
An unusual cause of abdominal pain: duodenal cystic lymphangioma. (23961273)
2013
8
Differentiating a large abdominal cystic lymphangioma from multicystic mesothelioma: report of a case. (23807639)
2013
9
Intestinal obstruction complicating a mesenteric cystic lymphangioma. (22795361)
2012
10
Huge cystic lymphangioma of the pancreas mimicking pancreatic cystic neoplasm. (23197988)
2012
11
Cystic fibrosis and retroperitoneal cystic lymphangioma: a novel match. (22273284)
2012
12
A case of laparoscopic excision of a huge retroperitoneal cystic lymphangioma. (22606623)
2011
13
Cystic lymphangioma of the breast in a 6-year-old boy. (19853765)
2009
14
Retroperitoneal cystic lymphangioma: a rare presentation in childhood, treated laparoscopically. (19215217)
2009
15
Cystic lymphangioma-like adenomatoid tumor of the adrenal gland: Case presentation and review of the literature. (19851133)
2009
16
Cystic lymphangioma of the gallbladder: report of a case. (18085372)
2008
17
Lingual cystic lymphangioma in an elderly patient. (19052498)
2008
18
Cystic lymphangioma of the lesser sac presenting as acute appendicitis: A case report. (18783617)
2008
19
Cystic lymphangioma of the pancreas. (17368224)
2007
20
Cystic lymphangioma of the lesser sac. (16955953)
2006
21
Prenatal diagnosis of a fetal chest wall cystic lymphangioma using ultrasonography and MRI: a case report with literature review. (16260884)
2005
22
Image of the month. Cystic lymphangioma. (16027339)
2005
23
Mesenteric cystic lymphangioma causing intestinal occlusion in an adult patient. (14722994)
2003
24
Asymptomatic adult cystic lymphangioma of the spleen: case report and review of the literature. (12620551)
2003
25
Antepartum assessment of fetal cystic lymphangioma by magnetic resonance imaging. (12186991)
2002
26
Abdominal cystic lymphangioma: a rare cause of acute abdomen in a neonate. (11737721)
2001
27
Giant cystic lymphangioma of the stomach. (11841086)
2001
28
Huge cystic lymphangioma of the pancreas: report of a case. (11510617)
2001
29
Abdominal cystic lymphangioma in a woman at 14 weeks' gestation: case report. (11055491)
2000
30
Cystic lymphangioma in an asymptomatic newborn: an uncommon localization in the ileum. (10204513)
1999
31
Bilateral cystic lymphangioma of the adrenal gland. (10219366)
1999
32
Mediastinal cystic lymphangioma: report of two cases. (9323827)
1997
33
Progressive fetal axillary cystic lymphangioma with coexistent naevus flammeus. (9039304)
1997
34
Prenatal ultrasonographic findings of intra-abdominal cystic lymphangioma: a case report. (9142629)
1997
35
Radiology/pathology conference: mesenteric cystic lymphangioma. (8692443)
1996
36
Abdominal cystic lymphangioma in children: benign lesions that can have a proliferative course. (8861480)
1996
37
Cystic lymphangioma of the transverse colon: report of a case and review of the literature. (8832861)
1996
38
Laparoscopic resection of a retroperitoneal cystic lymphangioma. (7878511)
1994
39
Intra-abdominal cystic lymphangioma. (7927442)
1994
40
Cystic lymphangioma of the kidney: a rare cause of multiloculated renal masses. (1999216)
1991
41
Abdominal cystic lymphangioma. A case report and a review of the literature. (2180901)
1990
42
Hyponatremia resulting from loss of lymphatic fluid in an infant with cystic lymphangioma. (3723245)
1986
43
Sonographic appearance of an abdominal cystic lymphangioma. (6699930)
1984
44
Solitary cystic lymphangioma of the retroperitoneum. (904040)
1977
45
Cystic lymphangioma of the cecum with ileocecal intussusception: Case report. (1163907)
1975
46
Case report: Cystic lymphangioma of the vallecula. (1131722)
1975
47
Symptomatic venous compression from a mediastinal cystic lymphangioma. (4574172)
1973
48
Cystic lymphangioma of the parotid region. (14417246)
1960
49
Ureteral obstruction due to retroperitoneal lymphatic cyst (cystic lymphangioma). (13655395)
1959
50
CYSTIC LYMPHANGIOMA OF THE GREAT OMENTUM. (17863276)
1914

Variations for Cystic Lymphangioma

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Expression for genes affiliated with Cystic Lymphangioma

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Search GEO for disease gene expression data for Cystic Lymphangioma.

Pathways for genes affiliated with Cystic Lymphangioma

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Pathways related to Cystic Lymphangioma according to GeneCards Suite gene sharing:

(show all 16)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.9CHRNG, CHRND
29.7AFP, IFNG
39.7TGFB1, PTCH1
4
Show member pathways
9.6IFNG, TGFB1
59.6IFNG, TGFB1
69.6IFNG, TGFB1
7
Show member pathways
9.6IFNG, TGFB1
8
Show member pathways
9.6IFNG, TGFB1
99.6IFNG, TGFB1
109.6IFNG, TGFB1
119.6IFNG, TGFB1
129.6TGFB1, IFNG
13
Show member pathways
IL27-mediated signaling events36
9.6IFNG, TGFB1
14
Show member pathways
9.4CHRNG, CHRND, TGFB1
15
Show member pathways
9.4CHRNG, CHRND, TGFB1

Compounds for genes affiliated with Cystic Lymphangioma

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Compounds related to Cystic Lymphangioma according to GeneCards Suite gene sharing:

(show all 21)
idCompoundScoreTop Affiliating Genes
1galantamine43 49 1212.2CHRNG, CHRND
2acyclovir43 1211.0IFNG, AFP
3con a4310.0IFNG, AFP
4tranilast439.9IFNG, TGFB1
5pirfenidone43 5910.9TGFB1, IFNG
6gm-csf43 2810.9IFNG, TGFB1
7anti-fungal439.9IFNG, AFP
8methylcellulose439.9TGFB1, IFNG
9ribavirin43 49 1211.8IFNG, AFP
10il 10439.8IFNG, TGFB1
114-hydroxytamoxifen439.7TGFB1, IFNG
12polyethylene glycol439.6TGFB1, AFP
13pdtc439.6IFNG, TGFB1
14bleomycin43 1210.5AFP, TGFB1
15butyrate439.5AFP, TGFB1, IFNG
16paraffin439.5AFP, PTCH1, TGFB1
17actinomycin d439.5IFNG, TGFB1, AFP
18carboplatin43 49 1211.4IFNG, DSCAM, AFP
19thalidomide43 49 59 1212.4IFNG, AFP
20thymidine43 2410.3IFNG, TGFB1, AFP
21paclitaxel43 49 1211.3AFP, TGFB1, DSCAM

GO Terms for genes affiliated with Cystic Lymphangioma

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Cellular components related to Cystic Lymphangioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1acetylcholine-gated channel complexGO:00058929.9CHRNG, CHRND

Biological processes related to Cystic Lymphangioma according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1muscle contractionGO:00069369.9CHRNG, CHRND
2protein import into nucleus, translocationGO:00000609.8IFNG, TGFB1
3extrinsic apoptotic signaling pathwayGO:00971919.8IFNG, TGFB1
4regulation of membrane potentialGO:00423919.8CHRNG, CHRND
5negative regulation of epithelial cell proliferationGO:00506809.7TGFB1, PTCH1
6transportGO:00068109.6CHRNG, CHRND, AFP
7response to estradiolGO:00323559.4TGFB1, PTCH1
8response to drugGO:00424939.3PTCH1, TGFB1, IFNG

Molecular functions related to Cystic Lymphangioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1acetylcholine-activated cation-selective channel activityGO:00048899.9CHRNG, CHRND

Products for genes affiliated with Cystic Lymphangioma

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Sources for Cystic Lymphangioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet