MCID: CYS017
MIFTS: 43

Cystic Teratoma malady

Cancer diseases category
Download this MalaCard

Summaries for Cystic Teratoma

About this section


Fully expand this MalaCard
MalaCards based summary: Cystic Teratoma is related to teratoma and pseudomyxoma peritonei. An important gene associated with Cystic Teratoma is TP53 (tumor protein p53), and among its related pathways are Peptide hormone metabolism and Selected targets of Oct 3 4. The compounds dutp and bleomycin have been mentioned in the context of this disorder. Affiliated tissues include ovary, pancreas and liver, and related mouse phenotypes are limbs/digits/tail and tumorigenesis.

Aliases & Classifications for Cystic Teratoma

About this section

Cystic Teratoma, Aliases & Descriptions:

Name: Cystic Teratoma 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:2660
SNOMED-CT57 42717009
NCIt39 C9014

Related Diseases for Cystic Teratoma

About this section

Diseases in the Cystic Teratoma family:

Adult Cystic Teratoma

Diseases related to Cystic Teratoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 137)
idRelated DiseaseScoreTop Affiliating Genes
1teratoma32.3ACTC1, CGB
2pseudomyxoma peritonei30.9CDX2, MUC2
3melanoma30.7CGB, CDX2, ACTC1, TP53
4endometrial carcinoma30.4CDX2, TP53
5papilloma30.3KRT10, ACTC1, TP53
6sarcoma30.2CGB, ACTC1, TP53
7cervical cancer30.2KRT10, TP53
8rhabdomyosarcoma30.2TP53, ACTC1
9papillary carcinoma30.0ACTC1, MUC2
10adenocarcinoma30.0TP53, MUC2, ACTC1, KRT10, CDX2, CGB
11ovarian cancer29.9TP53, MUC2, CDX2
12breast cancer29.7TP53, MUC2, CDX2, CGB
13adenoma29.6TP53, MUC2, ACTC1, CDX2, CGB
14ovarian cystic teratoma10.9
15mediastinitis10.7
16teratoma with malignant transformation10.5
17thyroiditis10.5
18ductal carcinoma in situ10.5TP53
19mucinous adenocarcinoma10.4
20cystadenocarcinoma10.4
21mucinous cystadenocarcinoma10.4
22peritonitis10.4
23adult cystic teratoma10.3
24cystadenoma10.3
25neuroectodermal tumor10.3
26prostatitis10.3
27ectopic pregnancy10.3
28dermoid cyst of ovary10.3
29hypercalcemia10.3
30adenosquamous carcinoma10.3
31ovarian mucinous cystadenocarcinoma10.3
32encephalitis10.3
33neuroblastoma10.3
34pancreatitis10.3
35malignant mixed mullerian tumor10.2TP53, ACTC1
36gastritis10.2TP53, CDX2
37neuroendocrine carcinoma10.2
38small cell carcinoma10.2
39paraganglioma10.2
40cystic lymphangioma10.2
41angiosarcoma10.2
42endodermal sinus tumor10.2
43intestinal obstruction10.2
44leiomyoma10.2
45lipoma10.2
46lymphangioma10.2
47oligodendroglioma10.2
48osteosarcoma10.2
49vaginitis10.2
50renal dysplasia10.2

Graphical network of the top 20 diseases related to Cystic Teratoma:



Diseases related to cystic teratoma

Symptoms for Cystic Teratoma

About this section

Drugs & Therapeutics for Cystic Teratoma

About this section

Drug clinical trials:

Search ClinicalTrials for Cystic Teratoma

Search NIH Clinical Center for Cystic Teratoma

Genetic Tests for Cystic Teratoma

About this section

Anatomical Context for Cystic Teratoma

About this section

MalaCards organs/tissues related to Cystic Teratoma:

32
Ovary, Pancreas, Liver, Thyroid, Colon, Testis, Lung, Prostate, Skin, Appendix, Pituitary, Small intestine, Breast, Uterus, Spleen, Thymus, Brain, Cerebellum, Heart, Kidney, Salivary gland, Adrenal gland, Testes, Cervix, Pineal, Lymph node

Animal Models for Cystic Teratoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Cystic Teratoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053719.1CDX2, KRT10, TP53
2MP:00020068.3CDX2, KRT10, MUC2, TP53
3MP:00053858.0CDX2, ACTC1, MUC2, TP53
4MP:00053787.7TP53, MUC2, ACTC1, KRT10, CDX2
5MP:00107687.6TP53, MUC2, ACTC1, KRT10, CDX2

Publications for Cystic Teratoma

About this section

Articles related to Cystic Teratoma:

(show top 50)    (show all 539)
idTitleAuthorsYear
1
Unusually High Levels of CA19-9 Associated with Mature Cystic Teratoma of the Ovary. (25276448)
2014
2
Clinical experience in ovarian squamous cell carcinoma arising from mature cystic teratoma: A rare entity. (25105100)
2014
3
Intrapericardial mature cystic teratoma in an adult: case presentation. (23007804)
2013
4
Benign mature cystic teratoma mimicking normal mandibular development. (24246392)
2013
5
Primary lymphoma arising in a mature cystic teratoma of the ovary. (23163645)
2012
6
Large cell neuroendocrine carcinoma arising in mature cystic teratoma: a case report and review of the literature. (23091901)
2012
7
Mucinous adenocarcinoma of the intestinal type arising from mature cystic teratoma of the ovary: a rare case report and review of the literature. (23216975)
2012
8
Concomitant squamous cell and thyroid carcinoma in a case of bilateral mature cystic teratoma. (21439712)
2011
9
Origin of uterine teratoma differs from that of ovarian teratoma: a case of uterine mature cystic teratoma. (21979590)
2011
10
Mediastinal mature cystic teratoma perforating into the lung. (20876619)
2010
11
Mature cystic teratoma of the fallopian tube. (20627241)
2010
12
Primary adenocarcinoid tumor of the ovary arising in mature cystic teratoma. A case report. (19317273)
2009
13
Mature cystic teratoma: Unusual presentation as dysphagia. (20108063)
2009
14
Angiosarcoma arising in mature cystic teratoma of the ovary: a case report and review of the literature. (19696615)
2009
15
Malignant transformation of mature cystic teratoma of the ovary: experience at a single institution. (18823690)
2008
16
Irregular dental structures in a benign ovarian cystic teratoma (dermoid cyst): case report. (18581775)
2008
17
Coexistence of interstitial cell of Cajal hyperplasia and microcarcinoidosis in a mature cystic teratoma of the ovary. (18036169)
2008
18
Severe chemical peritonitis caused by spontaneous rupture of an ovarian mature cystic teratoma: a case report. (17977177)
2007
19
Chylopericardium presenting as cardiac tamponade secondary to an anterior mediastinal cystic teratoma. (17948094)
2007
20
Mature cystic teratoma in the falciform ligament of the liver. (17244973)
2007
21
Interstitial cells of Cajal (ICC) in mature cystic teratoma of the ovary. (16405675)
2006
22
Mature cystic teratoma in the anterior mediastinum containing a carcinoid. (16538161)
2006
23
"Primary" benign retroperitoneal and intraspinal dumbbell-shaped cystic teratoma: case report. (16094263)
2005
24
Ovarian mature cystic teratoma exhibiting well-differentiated cerebellum in a 14-year-old female. (15747101)
2005
25
Mediastinal cystic teratoma. (15276587)
2004
26
Retrorectal benign cystic teratoma misdiagnosed with high lying pararectal abscess. (15244193)
2003
27
An adolescent with ovarian osteosarcoma arising in a cystic teratoma. (12759630)
2003
28
Mature cystic teratoma of the ovary associated with complete colonic wall and mucinous cystadenoma. (14584762)
2003
29
Large, complex, benign cystic teratoma in an adolescent. (12002202)
2002
30
Heterotopic omental ossification in response to spilled contents of a mature cystic teratoma: an unusual reaction. (12460211)
2002
31
Immunohistochemical detection of parathyroid hormone-related protein in a squamous cell carcinoma arising from mature cystic teratoma causing humoral hypercalcemia of malignancy. (11104629)
2000
32
Benign cystic teratoma of the ovary : a review of 608 patients. (11075967)
2000
33
Mature cystic teratoma of the mediastinum containing a carcinoid. A case report. (10323087)
1998
34
Cystic teratoma of the greater omentum: a case report and review of the literature. (9311177)
1997
35
Preoperative evaluation of cystic teratoma: what does color Doppler add? (9142626)
1997
36
CA19-9 in mature cystic teratoma. (8073424)
1994
37
Mature cystic teratoma: a clinicopathologic evaluation of 517 cases and review of the literature. (8008317)
1994
38
Well-differentiated adenocarcinoma arising from mature cystic teratoma of the mediastinum (teratoma with malignant transformation). Report of a surgical case. (8160647)
1994
39
Combined cystic teratoma and hepatoblastoma of the liver. Probable divergent differentiation of an uncommitted hepatic precursor cell. (8221556)
1993
40
Adenocarcinoma in a benign cystic teratoma of the ovary: report of a case with a long survival period. (8381377)
1993
41
Case of the day. Presacral cystic teratoma. (8497035)
1993
42
Mature cystic teratoma of the uterine cervix. (2099732)
1990
43
Sertoli-Leydig cell tumor associated with a mature cystic teratoma in a single ovary. (2587573)
1989
44
A young woman with vague lower abdominal pain. Benign cystic teratoma (dermoid cyst). (2735042)
1989
45
Cystic teratoma in the bare area of liver. (3294587)
1987
46
Stage II benign cystic teratoma with malignant squamous degeneration. (3859769)
1985
47
A cystic teratoma in skin. (3842792)
1985
48
Benign cystic teratoma of the ovary: a 6-year review. (4027793)
1985
49
A follicular adenoma arising from the thyroid tissue of a benign cystic teratoma during pregnancy--lightmicroscopical, ultrastructural and endocrinological studies. (7240873)
1980
50
Squamous cell carcinoma in situ arising in adult cystic teratoma of the ovary. (5009017)
1972

Variations for Cystic Teratoma

About this section

Expression for genes affiliated with Cystic Teratoma

About this section
Expression patterns in normal tissues for genes affiliated with Cystic Teratoma

Search GEO for disease gene expression data for Cystic Teratoma.

Pathways for genes affiliated with Cystic Teratoma

About this section

Pathways related to Cystic Teratoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.4CGB, CDX2
29.0CGB, CDX2, TP53
3
Show member pathways
8.6CGB, CDX2, MUC2

Compounds for genes affiliated with Cystic Teratoma

About this section

Compounds related to Cystic Teratoma according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
1dutp449.8KRT10, TP53
2bleomycin44 1110.7CGB, TP53
3crcs449.5TP53, MUC2
4vincristine44 50 1111.5CGB, TP53
5deoxycholic acid44 28 24 1112.5CDX2, MUC2
6cyclophosphamide44 50 1111.3TP53, CGB
7steroid449.2ACTC1, KRT10, CDX2
85-aza-2deoxycytidine449.1TP53, MUC2, CDX2
9butyrate449.1CDX2, MUC2, TP53
10vegf449.0TP53, ACTC1, CGB
11proline449.0KRT10, MUC2, TP53
12oligonucleotide449.0CDX2, MUC2, TP53
13hematoxylin448.9KRT10, ACTC1, MUC2
14dexamethasone44 50 28 1111.8KRT10, ACTC1, MUC2
15glucose448.5CGB, ACTC1, MUC2
16retinoic acid44 249.5TP53, MUC2, ACTC1, KRT10
17cysteine448.3CGB, CDX2, MUC2
18calcium44 50 24 1111.2CDX2, KRT10, ACTC1, MUC2
19paraffin448.1TP53, MUC2, ACTC1, KRT10, CDX2
20progesterone44 28 61 24 1111.5CGB, CDX2, KRT10, ACTC1, MUC2, TP53
21estrogen447.5TP53, MUC2, ACTC1, KRT10, CDX2, CGB

GO Terms for genes affiliated with Cystic Teratoma

About this section

Biological processes related to Cystic Teratoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1apoptotic processGO:0069158.9CGB, ACTC1, TP53

Products for genes affiliated with Cystic Teratoma

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Cystic Teratoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet