MCID: CYS017
MIFTS: 38

Cystic Teratoma malady

Summaries for Cystic Teratoma

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MalaCards based summary: Cystic Teratoma, also known as mature teratoma, is related to teratoma and pseudomyxoma peritonei. An important gene associated with Cystic Teratoma is TP53 (tumor protein p53), and among its related pathways are Peptide hormone metabolism and Selected targets of Oct 3 4. The compounds dutp and bleomycin have been mentioned in the context of this disorder. Affiliated tissues include ovary, pancreas and liver, and related mouse phenotypes are limbs/digits/tail and tumorigenesis.

Aliases & Classifications for Cystic Teratoma

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Cystic Teratoma, Aliases & Descriptions:

Name: Cystic Teratoma 9 60
Mature Teratoma 60
 
Dermoid Cyst 60


External Ids:

Disease Ontology9 DOID:2660
SNOMED-CT55 42717009
NCIt38 C9014

Related Diseases for Cystic Teratoma

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Diseases in the Cystic Teratoma family:

Adult Cystic Teratoma

Diseases related to Cystic Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 134)
idRelated DiseaseScoreTop Affiliating Genes
1teratoma32.3ACTC1, CGB
2pseudomyxoma peritonei30.9CDX2, MUC2
3melanoma30.7CGB, CDX2, ACTC1, TP53
4papilloma30.3KRT10, ACTC1, TP53
5sarcoma30.2CGB, ACTC1, TP53
6rhabdomyosarcoma30.2TP53, ACTC1
7papillary carcinoma30.0ACTC1, MUC2
8adenocarcinoma30.0TP53, MUC2, ACTC1, KRT10, CDX2, CGB
9breast cancer29.7TP53, MUC2, CDX2, CGB
10adenoma29.6TP53, MUC2, ACTC1, CDX2, CGB
11ovarian cystic teratoma11.0
12mediastinitis10.7
13teratoma with malignant transformation10.5
14thyroiditis10.5
15ductal carcinoma in situ10.4TP53
16mucinous adenocarcinoma10.4
17cystadenocarcinoma10.4
18adult cystic teratoma10.4
19mucinous cystadenocarcinoma10.4
20peritonitis10.4
21neuroectodermal tumor10.4
22prostatitis10.4
23ectopic pregnancy10.4
24neuroblastoma10.3
25cystadenoma10.3
26dermoid cyst of ovary10.3
27hypercalcemia10.3
28ovarian mucinous cystadenocarcinoma10.3
29adenosquamous carcinoma10.3
30encephalitis10.3
31pancreatitis10.3
32endometrial cancer10.2CDX2, TP53
33malignant mixed mullerian tumor10.2TP53, ACTC1
34lipoma10.2
35neuroendocrine carcinoma10.2
36ovarian squamous cell carcinoma10.2
37cystic lymphangioma10.2
38small cell carcinoma10.2
39paraganglioma10.2
40angiosarcoma10.2
41endodermal sinus tumor10.2
42intestinal obstruction10.2
43leiomyoma10.2
44lymphangioma10.2
45oligodendroglioma10.2
46vaginitis10.2
47renal dysplasia10.2
48gastritis10.2TP53, CDX2
49leiomyosarcoma10.2ACTC1, TP53
50carcinoid syndrome10.1CDX2, ACTC1

Graphical network of the top 20 diseases related to Cystic Teratoma:



Diseases related to cystic teratoma

Symptoms for Cystic Teratoma

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Drugs & Therapeutics for Cystic Teratoma

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Drug clinical trials:

Search ClinicalTrials for Cystic Teratoma

Search NIH Clinical Center for Cystic Teratoma

Genetic Tests for Cystic Teratoma

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Anatomical Context for Cystic Teratoma

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MalaCards organs/tissues related to Cystic Teratoma:

31
Ovary, Pancreas, Liver, Thyroid, Colon, Testis, Lung, Skin, Prostate, Appendix, Pituitary, Small intestine, Breast, Uterus, Spleen, Thymus, Brain, Cerebellum, Heart, Kidney, Salivary gland, Adrenal gland, Testes, Cervix, B cells, Pineal, Lymph node

Animal Models for Cystic Teratoma or affiliated genes

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MGI Mouse Phenotypes related to Cystic Teratoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053719.1CDX2, KRT10, TP53
2MP:00020068.3CDX2, KRT10, MUC2, TP53
3MP:00053858.0CDX2, ACTC1, MUC2, TP53
4MP:00053787.7TP53, MUC2, ACTC1, KRT10, CDX2
5MP:00107687.6TP53, MUC2, ACTC1, KRT10, CDX2

Publications for Cystic Teratoma

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Articles related to Cystic Teratoma:

(show top 50)    (show all 550)
idTitleAuthorsYear
1
Significant simultaneous changes in serum CA19-9 and CA125 due to prolonged torsion of mature cystic teratoma of the ovary. (25416055)
2014
2
Unusually High Levels of CA19-9 Associated with Mature Cystic Teratoma of the Ovary. (25276448)
2014
3
Clinical experience in ovarian squamous cell carcinoma arising from mature cystic teratoma: A rare entity. (25105100)
2014
4
Intrapericardial mature cystic teratoma in an adult: case presentation. (23007804)
2013
5
Benign mature cystic teratoma mimicking normal mandibular development. (24246392)
2013
6
Primary lymphoma arising in a mature cystic teratoma of the ovary. (23163645)
2012
7
Large cell neuroendocrine carcinoma arising in mature cystic teratoma: a case report and review of the literature. (23091901)
2012
8
Mucinous adenocarcinoma of the intestinal type arising from mature cystic teratoma of the ovary: a rare case report and review of the literature. (23216975)
2012
9
Concomitant squamous cell and thyroid carcinoma in a case of bilateral mature cystic teratoma. (21439712)
2011
10
Origin of uterine teratoma differs from that of ovarian teratoma: a case of uterine mature cystic teratoma. (21979590)
2011
11
Mediastinal mature cystic teratoma perforating into the lung. (20876619)
2010
12
Mature cystic teratoma of the fallopian tube. (20627241)
2010
13
Primary adenocarcinoid tumor of the ovary arising in mature cystic teratoma. A case report. (19317273)
2009
14
Mature cystic teratoma: Unusual presentation as dysphagia. (20108063)
2009
15
Angiosarcoma arising in mature cystic teratoma of the ovary: a case report and review of the literature. (19696615)
2009
16
Malignant transformation of mature cystic teratoma of the ovary: experience at a single institution. (18823690)
2008
17
Irregular dental structures in a benign ovarian cystic teratoma (dermoid cyst): case report. (18581775)
2008
18
Coexistence of interstitial cell of Cajal hyperplasia and microcarcinoidosis in a mature cystic teratoma of the ovary. (18036169)
2008
19
Severe chemical peritonitis caused by spontaneous rupture of an ovarian mature cystic teratoma: a case report. (17977177)
2007
20
Chylopericardium presenting as cardiac tamponade secondary to an anterior mediastinal cystic teratoma. (17948094)
2007
21
Mature cystic teratoma in the falciform ligament of the liver. (17244973)
2007
22
Interstitial cells of Cajal (ICC) in mature cystic teratoma of the ovary. (16405675)
2006
23
Mature cystic teratoma in the anterior mediastinum containing a carcinoid. (16538161)
2006
24
"Primary" benign retroperitoneal and intraspinal dumbbell-shaped cystic teratoma: case report. (16094263)
2005
25
Ovarian mature cystic teratoma exhibiting well-differentiated cerebellum in a 14-year-old female. (15747101)
2005
26
Mediastinal cystic teratoma. (15276587)
2004
27
Retrorectal benign cystic teratoma misdiagnosed with high lying pararectal abscess. (15244193)
2003
28
An adolescent with ovarian osteosarcoma arising in a cystic teratoma. (12759630)
2003
29
Mature cystic teratoma of the ovary associated with complete colonic wall and mucinous cystadenoma. (14584762)
2003
30
Large, complex, benign cystic teratoma in an adolescent. (12002202)
2002
31
Heterotopic omental ossification in response to spilled contents of a mature cystic teratoma: an unusual reaction. (12460211)
2002
32
Immunohistochemical detection of parathyroid hormone-related protein in a squamous cell carcinoma arising from mature cystic teratoma causing humoral hypercalcemia of malignancy. (11104629)
2000
33
Benign cystic teratoma of the ovary : a review of 608 patients. (11075967)
2000
34
Mature cystic teratoma of the mediastinum containing a carcinoid. A case report. (10323087)
1998
35
Cystic teratoma of the greater omentum: a case report and review of the literature. (9311177)
1997
36
Preoperative evaluation of cystic teratoma: what does color Doppler add? (9142626)
1997
37
CA19-9 in mature cystic teratoma. (8073424)
1994
38
Well-differentiated adenocarcinoma arising from mature cystic teratoma of the mediastinum (teratoma with malignant transformation). Report of a surgical case. (8160647)
1994
39
Combined cystic teratoma and hepatoblastoma of the liver. Probable divergent differentiation of an uncommitted hepatic precursor cell. (8221556)
1993
40
Adenocarcinoma in a benign cystic teratoma of the ovary: report of a case with a long survival period. (8381377)
1993
41
Case of the day. Presacral cystic teratoma. (8497035)
1993
42
Mature cystic teratoma of the uterine cervix. (2099732)
1990
43
Sertoli-Leydig cell tumor associated with a mature cystic teratoma in a single ovary. (2587573)
1989
44
A young woman with vague lower abdominal pain. Benign cystic teratoma (dermoid cyst). (2735042)
1989
45
Cystic teratoma in the bare area of liver. (3294587)
1987
46
Stage II benign cystic teratoma with malignant squamous degeneration. (3859769)
1985
47
A cystic teratoma in skin. (3842792)
1985
48
Benign cystic teratoma of the ovary: a 6-year review. (4027793)
1985
49
A follicular adenoma arising from the thyroid tissue of a benign cystic teratoma during pregnancy--lightmicroscopical, ultrastructural and endocrinological studies. (7240873)
1980
50
Squamous cell carcinoma in situ arising in adult cystic teratoma of the ovary. (5009017)
1972

Variations for Cystic Teratoma

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Expression for genes affiliated with Cystic Teratoma

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Search GEO for disease gene expression data for Cystic Teratoma.

Pathways for genes affiliated with Cystic Teratoma

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Pathways related to Cystic Teratoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.4CGB, CDX2
2
Show member pathways
8.6CGB, CDX2, MUC2

Compounds for genes affiliated with Cystic Teratoma

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Compounds related to Cystic Teratoma according to GeneCards Suite gene sharing:

(show all 21)
idCompoundScoreTop Affiliating Genes
1dutp439.8KRT10, TP53
2bleomycin43 1210.7CGB, TP53
3crcs439.5TP53, MUC2
4vincristine43 49 1211.5CGB, TP53
5deoxycholic acid43 28 24 1212.5CDX2, MUC2
6cyclophosphamide43 49 1211.3TP53, CGB
7steroid439.2ACTC1, KRT10, CDX2
85-aza-2deoxycytidine439.1TP53, MUC2, CDX2
9butyrate439.1CDX2, MUC2, TP53
10vegf439.0TP53, ACTC1, CGB
11proline439.0KRT10, MUC2, TP53
12oligonucleotide439.0CDX2, MUC2, TP53
13hematoxylin438.9KRT10, ACTC1, MUC2
14dexamethasone43 49 28 1211.8KRT10, ACTC1, MUC2
15glucose438.5CGB, ACTC1, MUC2
16retinoic acid43 249.5TP53, MUC2, ACTC1, KRT10
17cysteine438.3CGB, CDX2, MUC2
18calcium43 49 24 1211.2CDX2, KRT10, ACTC1, MUC2
19paraffin438.1TP53, MUC2, ACTC1, KRT10, CDX2
20progesterone43 28 59 24 1211.5CGB, CDX2, KRT10, ACTC1, MUC2, TP53
21estrogen437.5TP53, MUC2, ACTC1, KRT10, CDX2, CGB

GO Terms for genes affiliated with Cystic Teratoma

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Biological processes related to Cystic Teratoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1apoptotic processGO:00069158.9CGB, ACTC1, TP53

Products for genes affiliated with Cystic Teratoma

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Sources for Cystic Teratoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
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50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
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