MCID: CYS017
MIFTS: 44

Cystic Teratoma malady

Cancer diseases category
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Summaries for Cystic Teratoma

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33MalaCards
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MalaCards: Cystic Teratoma, also known as cystic teratoma, nos, is related to teratoma and melanoma. An important gene associated with Cystic Teratoma is TP53 (tumor protein p53), and among its related pathways are Peptide hormone metabolism and Selected targets of Oct 3 4. The compounds dutp and bleomycin have been mentioned in the context of this disorder. Affiliated tissues include ovary, pancreas and liver, and related mouse phenotypes are limbs/digits/tail and tumorigenesis.

Aliases & Classifications for Cystic Teratoma

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8Disease Ontology, 62UMLS, 40NCIt, 58SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

cystic teratoma 8 62
cystic teratoma, nos 8


External Ids:

Disease Ontology8 DOID:2660
SNOMED-CT58 42717009
NCIt40 C9014

Related Diseases for Cystic Teratoma

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17GeneCards, 18GeneDecks
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Diseases in the Cystic Teratoma family:

Adult Cystic Teratoma

Diseases related to Cystic Teratoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 134)
idRelated DiseaseScoreTop Affiliating Genes
1teratoma32.1ACTC1, CGB
2melanoma30.9CGB, CDX2, ACTC1, TP53
3adenocarcinoma30.9ACTC1, TP53, KRT10, CGB, CDX2, MUC2
4pseudomyxoma peritonei30.7CDX2, MUC2
5papilloma30.3KRT10, TP53, ACTC1
6sarcoma30.3TP53, ACTC1, CGB
7breast cancer30.1CGB, CDX2, MUC2, TP53
8adenoma30.1CGB, ACTC1, MUC2, CDX2, TP53
9cervical cancer30.1TP53, KRT10
10rhabdomyosarcoma30.1TP53, ACTC1
11papillary carcinoma30.0ACTC1, MUC2
12ovarian cancer30.0CDX2, MUC2, TP53
13ovarian cystic teratoma10.9
14mediastinitis10.6
15teratoma with malignant transformation10.5
16thyroiditis10.5
17mucinous adenocarcinoma10.4
18cystadenocarcinoma10.4
19mucinous cystadenocarcinoma10.4
20peritonitis10.4
21adult cystic teratoma10.3
22prostatitis10.3
23ectopic pregnancy10.3
24cystadenoma10.3
25hypercalcemia10.3
26ovarian mucinous cystadenocarcinoma10.3
27adenosquamous carcinoma10.3
28pancreatitis10.3
29dermoid cyst of ovary10.2
30cystic lymphangioma10.2
31small cell carcinoma10.2
32paraganglioma10.2
33angiosarcoma10.2
34encephalitis10.2
35endodermal sinus tumor10.2
36intestinal obstruction10.2
37leiomyoma10.2
38lipoma10.2
39lymphangioma10.2
40osteosarcoma10.2
41primitive neuroectodermal tumor10.2
42renal dysplasia10.2
43ductal carcinoma in situ10.1TP53
44malignant mixed mullerian tumor10.1TP53, ACTC1
45endometrial carcinoma10.1CDX2, TP53
46gastritis10.0TP53, CDX2
47leiomyosarcoma10.0TP53, ACTC1
48cardiac tamponade10.0
49neuroendocrine carcinoma10.0
50blastoma10.0

Graphical network of the top 20 diseases related to Cystic Teratoma:



Diseases related to cystic teratoma

Symptoms for Cystic Teratoma

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Drugs & Therapeutics for Cystic Teratoma

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Cystic Teratoma

Search NIH Clinical Center for Cystic Teratoma

Genetic Tests for Cystic Teratoma

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Anatomical Context for Cystic Teratoma

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33MalaCards
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MalaCards organs/tissues related to Cystic Teratoma:

33
Ovary, Pancreas, Liver, Thyroid, Colon, Testis, Prostate, Lung, Appendix, Breast, Pituitary, Small intestine, Skin, Uterus, Pineal, Testes, Cervix, Adrenal gland, Salivary gland, Kidney, Heart, Cerebellum, Brain, Thymus, Lymph node

Animal Models for Cystic Teratoma or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Cystic Teratoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053719.1CDX2, KRT10, TP53
2MP:00020068.3CDX2, KRT10, MUC2, TP53
3MP:00053858.0CDX2, ACTC1, MUC2, TP53
4MP:00053787.7TP53, MUC2, ACTC1, KRT10, CDX2
5MP:00107687.6TP53, MUC2, ACTC1, KRT10, CDX2

Publications for Cystic Teratoma

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52PubMed
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Articles related to Cystic Teratoma:

(show top 50)    (show all 508)
idTitleAuthorsYear
1
Intrapericardial mature cystic teratoma in an adult: case presentation. (23007804)
2013
2
Benign mature cystic teratoma mimicking normal mandibular development. (24246392)
2013
3
Primary lymphoma arising in a mature cystic teratoma of the ovary. (23163645)
2012
4
Large cell neuroendocrine carcinoma arising in mature cystic teratoma: a case report and review of the literature. (23091901)
2012
5
Mucinous adenocarcinoma of the intestinal type arising from mature cystic teratoma of the ovary: a rare case report and review of the literature. (23216975)
2012
6
Concomitant squamous cell and thyroid carcinoma in a case of bilateral mature cystic teratoma. (21439712)
2011
7
Origin of uterine teratoma differs from that of ovarian teratoma: a case of uterine mature cystic teratoma. (21979590)
2011
8
Mediastinal mature cystic teratoma perforating into the lung. (20876619)
2010
9
Mature cystic teratoma of the fallopian tube. (20627241)
2010
10
Primary adenocarcinoid tumor of the ovary arising in mature cystic teratoma. A case report. (19317273)
2009
11
Mature cystic teratoma: Unusual presentation as dysphagia. (20108063)
2009
12
Angiosarcoma arising in mature cystic teratoma of the ovary: a case report and review of the literature. (19696615)
2009
13
Malignant transformation of mature cystic teratoma of the ovary: experience at a single institution. (18823690)
2008
14
Irregular dental structures in a benign ovarian cystic teratoma (dermoid cyst): case report. (18581775)
2008
15
Coexistence of interstitial cell of Cajal hyperplasia and microcarcinoidosis in a mature cystic teratoma of the ovary. (18036169)
2008
16
Severe chemical peritonitis caused by spontaneous rupture of an ovarian mature cystic teratoma: a case report. (17977177)
2007
17
Chylopericardium presenting as cardiac tamponade secondary to an anterior mediastinal cystic teratoma. (17948094)
2007
18
Mature cystic teratoma in the falciform ligament of the liver. (17244973)
2007
19
Interstitial cells of Cajal (ICC) in mature cystic teratoma of the ovary. (16405675)
2006
20
Mature cystic teratoma in the anterior mediastinum containing a carcinoid. (16538161)
2006
21
"Primary" benign retroperitoneal and intraspinal dumbbell-shaped cystic teratoma: case report. (16094263)
2005
22
Ovarian mature cystic teratoma exhibiting well-differentiated cerebellum in a 14-year-old female. (15747101)
2005
23
Mediastinal cystic teratoma. (15276587)
2004
24
Retrorectal benign cystic teratoma misdiagnosed with high lying pararectal abscess. (15244193)
2003
25
An adolescent with ovarian osteosarcoma arising in a cystic teratoma. (12759630)
2003
26
Mature cystic teratoma of the ovary associated with complete colonic wall and mucinous cystadenoma. (14584762)
2003
27
Granulosa cell tumor co-existing with a mature cystic teratoma of the ovary. (12918483)
2003
28
Large, complex, benign cystic teratoma in an adolescent. (12002202)
2002
29
Heterotopic omental ossification in response to spilled contents of a mature cystic teratoma: an unusual reaction. (12460211)
2002
30
Immunohistochemical detection of parathyroid hormone-related protein in a squamous cell carcinoma arising from mature cystic teratoma causing humoral hypercalcemia of malignancy. (11104629)
2000
31
Benign cystic teratoma of the ovary : a review of 608 patients. (11075967)
2000
32
Mature cystic teratoma of the mediastinum containing a carcinoid. A case report. (10323087)
1998
33
Cystic teratoma of the greater omentum: a case report and review of the literature. (9311177)
1997
34
Preoperative evaluation of cystic teratoma: what does color Doppler add? (9142626)
1997
35
CA19-9 in mature cystic teratoma. (8073424)
1994
36
Mature cystic teratoma: a clinicopathologic evaluation of 517 cases and review of the literature. (8008317)
1994
37
Well-differentiated adenocarcinoma arising from mature cystic teratoma of the mediastinum (teratoma with malignant transformation). Report of a surgical case. (8160647)
1994
38
Combined cystic teratoma and hepatoblastoma of the liver. Probable divergent differentiation of an uncommitted hepatic precursor cell. (8221556)
1993
39
Adenocarcinoma in a benign cystic teratoma of the ovary: report of a case with a long survival period. (8381377)
1993
40
Case of the day. Presacral cystic teratoma. (8497035)
1993
41
Benign cystic teratoma manifested as an umbilical hernia. (2000537)
1991
42
Mature cystic teratoma of the uterine cervix. (2099732)
1990
43
Sertoli-Leydig cell tumor associated with a mature cystic teratoma in a single ovary. (2587573)
1989
44
A young woman with vague lower abdominal pain. Benign cystic teratoma (dermoid cyst). (2735042)
1989
45
A filarial worm in the wall of a cystic teratoma of the ovary--(a case report). (2641522)
1989
46
Cystic teratoma in the bare area of liver. (3294587)
1987
47
Stage II benign cystic teratoma with malignant squamous degeneration. (3859769)
1985
48
Benign cystic teratoma of the ovary: a 6-year review. (4027793)
1985
49
A follicular adenoma arising from the thyroid tissue of a benign cystic teratoma during pregnancy--lightmicroscopical, ultrastructural and endocrinological studies. (7240873)
1980
50
Squamous cell carcinoma in situ arising in adult cystic teratoma of the ovary. (5009017)
1972

Variations for Cystic Teratoma

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Expression for genes affiliated with Cystic Teratoma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cystic Teratoma

Search GEO for disease gene expression data for Cystic Teratoma.

Pathways for genes affiliated with Cystic Teratoma

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50PathCards, 55Reactome, 38NCBI BioSystems Database, 12EMD Millipore, 30KEGG
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Pathways related to Cystic Teratoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.4CGB, CDX2
29.0CGB, CDX2, TP53
3
Show member pathways
8.6CGB, CDX2, MUC2

Compounds for genes affiliated with Cystic Teratoma

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45Novoseek, 11DrugBank, 51PharmGKB, 29IUPHAR, 24HMDB, 61Tocris Bioscience
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Compounds related to Cystic Teratoma according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
1dutp459.8KRT10, TP53
2bleomycin45 1110.7CGB, TP53
3crcs459.5TP53, MUC2
4vincristine45 51 1111.5CGB, TP53
5deoxycholic acid45 29 24 1112.5CDX2, MUC2
6cyclophosphamide45 51 1111.3TP53, CGB
7steroid459.2ACTC1, KRT10, CDX2
85-aza-2deoxycytidine459.1TP53, MUC2, CDX2
9butyrate459.1CDX2, MUC2, TP53
10vegf459.0TP53, ACTC1, CGB
11proline459.0KRT10, MUC2, TP53
12oligonucleotide459.0CDX2, MUC2, TP53
13hematoxylin458.9KRT10, ACTC1, MUC2
14dexamethasone45 51 29 1111.8KRT10, ACTC1, MUC2
15glucose458.5CGB, ACTC1, MUC2
16retinoic acid45 249.5TP53, MUC2, ACTC1, KRT10
17cysteine458.3CGB, CDX2, MUC2
18calcium45 51 24 1111.2CDX2, KRT10, ACTC1, MUC2
19paraffin458.1TP53, MUC2, ACTC1, KRT10, CDX2
20progesterone45 29 61 24 1111.5CGB, CDX2, KRT10, ACTC1, MUC2, TP53
21estrogen457.5TP53, MUC2, ACTC1, KRT10, CDX2, CGB

GO Terms for genes affiliated with Cystic Teratoma

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16Gene Ontology
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Biological processes related to Cystic Teratoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1apoptotic processGO:0069158.9CGB, ACTC1, TP53

Products for genes affiliated with Cystic Teratoma

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Sources for Cystic Teratoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet