Aliases & Classifications for Cystic Teratoma

MalaCards integrated aliases for Cystic Teratoma:

Name: Cystic Teratoma 12 14 69
Benign Teratoma 69
Dermoid Cyst 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2660
NCIt 46 C9014
SNOMED-CT 64 42717009

Summaries for Cystic Teratoma

MalaCards based summary : Cystic Teratoma, also known as benign teratoma, is related to ovarian cystic teratoma and dermoid cyst. An important gene associated with Cystic Teratoma is KRT7 (Keratin 7), and among its related pathways/superpathways is Neuroscience. The drugs Bleomycin and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include ovary, bone marrow and bone.

Related Diseases for Cystic Teratoma

Diseases in the Cystic Teratoma family:

Adult Cystic Teratoma

Diseases related to Cystic Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 423)
# Related Disease Score Top Affiliating Genes
1 ovarian cystic teratoma 33.6 KRT20 KRT7 NKX2-1
2 dermoid cyst 32.6 KRT20 KRT7
3 intestinal obstruction 30.1 CDX2 KRT20 KRT7
4 papilloma 30.1 KRT20 KRT7 TP53
5 ovarian carcinosarcoma 30.0 ENO2 SYP
6 ovarian germ cell teratoma 30.0 KRT7 NKX2-1
7 mucinous cystadenocarcinoma 30.0 KRT20 KRT7 MUC2
8 adenocarcinoma in situ 29.9 CDX2 KRT20 KRT7
9 cystadenocarcinoma 29.9 KRT7 MUC2 TP53
10 ganglioneuroblastoma 29.7 ENO2 SYP
11 papilloma of choroid plexus 29.6 GFAP SYP TP53
12 papillary carcinoma 29.6 KRT20 KRT7 NKX2-1
13 ganglioneuroma 29.6 ENO2 GFAP SYP
14 granular cell tumor 29.6 ENO2 GFAP
15 adenoma 29.6 KRT7 MUC2 TP53
16 blastoma 29.5 NKX2-1 SYP TP53
17 teratoma 29.4 CDX2 ENO2 GFAP KRT20 KRT7 NKX2-1
18 oligodendroglioma 29.4 ENO2 GFAP SYP TP53
19 central neurocytoma 29.4 ENO2 GFAP SYP
20 astrocytoma 29.3 GFAP SYP TP53
21 meningioma, familial 29.3 GFAP SYP TP53
22 ovarian mucinous adenocarcinoma 29.0 CDX2 KRT20 KRT7 MUC2
23 neuroendocrine tumor 29.0 ENO2 KRT20 KRT7 NKX2-1 SYP
24 central nervous system primitive neuroectodermal neoplasm 28.9 ENO2 GFAP SYP TP53
25 endocervical adenocarcinoma 28.9 CDX2 KRT20 KRT7 MUC6 TP53
26 cystadenoma 28.8 KRT20 KRT7 MUC2 MUC6 SYP
27 large cell neuroendocrine carcinoma 28.8 ENO2 KRT20 KRT7 NKX2-1 SYP
28 mucinous adenocarcinoma 28.7 CDX2 KRT20 KRT7 MUC2 NKX2-1 TP53
29 small cell carcinoma 28.7 ENO2 KRT20 KRT7 NKX2-1 SYP TP53
30 horseshoe kidney 28.7 CDX2 ENO2 KRT20 KRT7 NKX2-1 SYP
31 pseudomyxoma peritonei 28.6 CDX2 KRT20 KRT7 MUC2 MUC6 TP53
32 adult cystic teratoma 12.2
33 squamous cell carcinoma 10.6
34 cystic basal cell carcinoma 10.5 KRT20 KRT7
35 seminal vesicle adenocarcinoma 10.5 KRT20 KRT7
36 transverse colon cancer 10.5 KRT20 KRT7
37 eyelid neoplasm 10.5 KRT20 KRT7
38 anal canal adenocarcinoma 10.5 CDX2 KRT7
39 malignant syringoma 10.5 KRT20 KRT7
40 krukenberg carcinoma 10.5 KRT20 KRT7
41 large intestine adenocarcinoma 10.5 KRT20 KRT7
42 linitis plastica 10.5 KRT20 KRT7
43 epithelial predominant wilms' tumor 10.5 CDX2 KRT7
44 adenoid squamous cell carcinoma 10.5 KRT20 KRT7
45 adenoma of the pancreas 10.5 KRT20 SYP
46 vulval paget's disease 10.5 KRT20 KRT7
47 intratubular embryonal carcinoma 10.5 KRT20 KRT7
48 meibomian cyst 10.5 KRT20 KRT7
49 villous adenoma 10.5 CDX2 KRT20
50 bladder lymphoma 10.5 KRT20 KRT7

Graphical network of the top 20 diseases related to Cystic Teratoma:



Diseases related to Cystic Teratoma

Symptoms & Phenotypes for Cystic Teratoma

Drugs & Therapeutics for Cystic Teratoma

Drugs for Cystic Teratoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 87)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bleomycin Approved, Investigational Phase 3,Phase 2 11056-06-7 5360373
2
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 2767 441203 84093
3
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
4
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
5
Mechlorethamine Approved, Investigational Phase 3,Phase 2,Phase 1 51-75-2 4033
6
Oxaliplatin Approved, Investigational Phase 3 61825-94-3 43805 6857599 5310940 9887054
7
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
8
Lenograstim Approved, Investigational Phase 2, Phase 3,Phase 1 135968-09-1
9
Captopril Approved Phase 3 62571-86-2 44093
10
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
11
Palivizumab Approved, Investigational Phase 3 188039-54-5
12
Ribavirin Approved Phase 3 36791-04-5 37542
13
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
14
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
15
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
16
Amphotericin B Approved, Investigational Phase 3 1397-89-3 5280965 14956
17
Caspofungin Approved Phase 3 162808-62-0, 179463-17-3 2826718 468682
18
Vinblastine Approved Phase 3 865-21-4 241903 13342
19 Albumin-Bound Paclitaxel Phase 3,Phase 2,Phase 1
20 Alkylating Agents Phase 3,Phase 2,Phase 1
21 Anti-Bacterial Agents Phase 3,Phase 2
22 Antibiotics, Antitubercular Phase 3,Phase 2
23 Antimitotic Agents Phase 3,Phase 2,Phase 1
24 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
25 Etoposide phosphate Phase 3,Phase 2
26 Isophosphamide mustard Phase 3,Phase 2,Phase 1 0
27 Topoisomerase Inhibitors Phase 3,Phase 2
28 Hormone Antagonists Phase 3,Phase 2,Phase 1
29 Hormones Phase 3,Phase 2,Phase 1
30 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
31 Angiotensin-Converting Enzyme Inhibitors Phase 3
32 Antihypertensive Agents Phase 3
33 Antirheumatic Agents Phase 3
34 HIV Protease Inhibitors Phase 3
35 Immunosuppressive Agents Phase 3,Phase 1,Phase 2
36
protease inhibitors Phase 3
37 Antibodies Phase 3,Phase 2,Phase 1
38 Antibodies, Monoclonal Phase 3,Phase 2,Phase 1
39 Anti-Infective Agents Phase 3,Phase 2
40 Antimetabolites Phase 3
41 Antiviral Agents Phase 3,Phase 2
42 Immunoglobulins Phase 3,Phase 2,Phase 1
43 Antifungal Agents Phase 3
44 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
45 Cytochrome P-450 CYP3A Inhibitors Phase 3
46 Cytochrome P-450 Enzyme Inhibitors Phase 3
47 Hydroxyitraconazole Phase 3
48 Steroid Synthesis Inhibitors Phase 3
49 Antiparasitic Agents Phase 3
50 Antiprotozoal Agents Phase 3

Interventional clinical trials:

(show all 37)

# Name Status NCT ID Phase Drugs
1 Safety and Efficacy of Antiadhesive Barrier GUARDIX-FL for Women After Laparoscopic Cystectomy Unknown status NCT02097446 Phase 3
2 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
3 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
4 Single-port LC Might be Preferable for Managing Ovarian Dermoid Cyst. Completed NCT02009228 Phase 3
5 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
6 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
7 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
8 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
9 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
10 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
11 High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy Unknown status NCT01172912 Phase 2 carboplatin;cisplatin;dexamethasone;etoposide;ifosfamide
12 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
13 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
14 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
15 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2 cisplatin;etoposide
16 Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin Completed NCT00423852 Phase 1, Phase 2 carboplatin;ifosfamide;paclitaxel
17 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2 carboplatin;cisplatin;etoposide phosphate;vincristine sulfate
18 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
19 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
20 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
21 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
22 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
23 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
24 PHASE II TRIAL OF THE CYCLIN-DEPEDENT KINASE INHIBITOR PD 0332991 IN PATIENTS WITH CANCER Recruiting NCT01037790 Phase 2 PD-0332991
25 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
26 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
27 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1 ipilimumab;therapeutic allogeneic lymphocytes
28 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
29 Epidural and Spinal Anesthesia Techniques in Pilonidal Dermoid Sinus Surgeries Unknown status NCT02580500
30 Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK) Unknown status NCT02224677
31 Ovarian Mesial Incision: a New Safe and Fertility-sparing Technique Completed NCT01590030
32 Serum Caspase 3, Annexin a2 and Soluble Fas Levels and Endometriosis Completed NCT03020108
33 Anterior Mediastinum Teratoma: A Case Report Completed NCT00836121
34 Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation Completed NCT00060021
35 Standard Follow-up Compared With Extended Follow-up in Treating Patients Who Have Undergone Stem Cell Transplantation for Cancer Completed NCT00049465
36 Corneal Epithelial Autograft for Limbal Dermoid Recruiting NCT03217461
37 Monitoring Ovarian Cysts in Pregnancy Not yet recruiting NCT03440931

Search NIH Clinical Center for Cystic Teratoma

Genetic Tests for Cystic Teratoma

Anatomical Context for Cystic Teratoma

MalaCards organs/tissues related to Cystic Teratoma:

38
Ovary, Bone Marrow, Bone, Pancreas, Colon, Thyroid, Liver

Publications for Cystic Teratoma

Articles related to Cystic Teratoma:

(show top 50) (show all 656)
# Title Authors Year
1
Bilateral ovarian angiosarcoma arising from the mature cystic teratomas - A case report and review of the literature. ( 29227858 )
2018
2
Mature cystic teratoma with high proportion of solid thyroid tissue: a controversial case with unusual imaging findings. ( 29299099 )
2017
3
Tumor markers and mature cystic teratoma of the ovary. ( 28882729 )
2017
4
Case Report: Low-Grade Astrocytoma Within A Mature Cystic Teratoma In An Adolescent Patient. ( 29107097 )
2017
5
De Novo Tumors of Teratoma: Ganglioneuroma Arising From a Mature Cystic Teratoma of the Ovary. ( 28700440 )
2017
6
Malignant Transformation of Mature Cystic Teratoma Diagnosed after a 10-Year Interval. ( 28607781 )
2017
7
Age-stratified analysis of tumor markers and tumor characteristics in adolescents and young women with mature cystic teratoma. ( 28826726 )
2017
8
Elevated preoperative neutrophil : lymphocyte ratio as a preoperative indicator of mature cystic teratoma with malignant transformation. ( 28370831 )
2017
9
Agenesis of the dorsal pancreas associated with mucinous adenocarcinoma and cystic teratoma: a case report and literature review. ( 28174646 )
2017
10
Mature Cystic Teratoma With an Element of Hepatocellular Carcinoma in Anterior Mediastinum: Magnetic Resonance-Pathologic Correlation. ( 28914742 )
2017
11
Clinicopathological Evaluation of 223 Cases of Mature Cystic Teratoma, Ovary: 25-Year Experience in a Single Tertiary Care Centre in India. ( 28571142 )
2017
12
Mesenteric Cystic Teratoma Masquerading as Acute Abdomen. ( 28432609 )
2017
13
Sebaceous adenoma arising in mature cystic teratoma of the ovary. Case report. ( 28248120 )
2017
14
Primary retroperitoneal mature cystic teratoma (dermoid cyst) in a 51-year-old male:Case report and historical literature review. ( 28540054 )
2017
15
Metastatic Mucinous Adenocarcinoma and Carcinoid Tumor Arising From a Mature Cystic Teratoma of a Horseshoe Kidney. ( 28083486 )
2017
16
Ovarian Adenomatoid Tumor Coexisting with Mature Cystic Teratoma: A Rare Case Report. ( 29085685 )
2017
17
Metastatic Endocervical Adenocarcinoma in a Mature Cystic Teratoma: A Case of a Tumor-to-Tumor Metastasis. ( 29140879 )
2017
18
A Rare Case of Primary Apocrine Adenocarcinoma Arising Within a Mature Cystic Teratoma of the Ovary, Metastatic to a Supraclavicular Lymph Node. ( 28787321 )
2017
19
Atypical presentation of mature cystic teratoma ("floating balls"). ( 28670039 )
2017
20
Melanoma arising in an ovarian cystic teratoma: a systematic review of presentation, treatment, and outcomes. ( 28643027 )
2017
21
Leiomyosarcoma and Squamous Cell Carcinoma Arising in Mature Cystic Teratoma of the Ovary. ( 28751996 )
2017
22
Carcinoid Arising From the Teratomatous Bronchial Mucosa in a Mature Cystic Teratoma of the Ovary: A Case Report. ( 28777098 )
2017
23
Primary malignant melanoma arising in an ovarian cystic teratoma. ( 29016386 )
2017
24
Unusual presentation of plasmablastic lymphoma involving ovarian mature cystic teratoma: a case report. ( 29187222 )
2017
25
Malignant transformation of mature cystic teratoma of the ovary: a case series. ( 28976117 )
2017
26
An ovarian mature cystic teratoma evolving in squamous cell carcinoma: A case report and review of the literature. ( 28050596 )
2017
27
A Rare Case of an Autoamputated Ovary with Mature Cystic Teratoma. ( 28523263 )
2017
28
The Driver Mutational Landscape of Ovarian Squamous Cell Carcinomas Arising in Mature Cystic Teratoma. ( 28954785 )
2017
29
A Cystic Teratoma Mimicking a Hydatid Cyst. ( 28766574 )
2017
30
Malignant transformation of ovarian mature cystic teratoma into squamous cell carcinoma: a Taiwanese Gynecologic Oncology Group (TGOG) study. ( 28657230 )
2017
31
A Case of Mature Cystic Teratoma in an 8-year-old Girl: A Rare Case Report. ( 28900332 )
2017
32
Carcinoid tumor arising from a retroperitoneal mature cystic teratoma. ( 29295805 )
2017
33
Simultaneous Mature Cystic Teratoma and Hydatid Cyst in a Young Female: An Unusual Coincidence. ( 29295660 )
2017
34
Mature Cystic Teratoma: AIRP Best Cases in Radiologic-Pathologic Correlation. ( 28898187 )
2017
35
Gliomatosis peritonei in mature cystic teratoma. ( 29323089 )
2017
36
Retroperitoneal Mature Cystic Teratoma in a Neonate: A Case Report. ( 27123399 )
2016
37
Advanced Mucinous Adenocarcinoma Arising from a Mature Cystic Teratoma: A Case Report and Literature Review. ( 27462234 )
2016
38
Ovarian mature cystic teratoma with fistula formation into the rectum: a case report. ( 27757372 )
2016
39
Relevance of frozen sections and serum markers in invasive squamous cell carcinoma arising from ovarian mature cystic teratoma: two case reports. ( 26801904 )
2016
40
A review of squamous cell carcinoma arising in mature cystic teratoma of the ovary. ( 28485364 )
2016
41
Squamous Cell Carcinoma Arising in Background of Mature Cystic Teratoma. ( 27981940 )
2016
42
Cystic teratoma mimicking recurrent pleural effusion, complicated by Mycobacterium abscessus infection. ( 27516884 )
2016
43
Mature Cystic Teratoma of the Pancreas. ( 26958551 )
2016
44
Rare case of complete colon structure in a mature cystic teratoma of the ovary in menopausal woman: a case report. ( 27793140 )
2016
45
Intestinal-Type Adenocarcinoma Arising in a Mature Cystic Teratoma of the Ovary. ( 26937866 )
2016
46
Primary mature cystic teratoma with carcinoid mimicking an adrenal tumor: Report of a rare association and review of literature. ( 27166041 )
2016
47
Superior mediastinal mature cystic teratoma with gastrointestinal adenocarcinoma transformation: Report of a case. ( 27221036 )
2016
48
Ovarian Carcinosarcoma and Its Association with Mature Cystic Teratoma and Primary Tubal Carcinoma. ( 27807494 )
2016
49
Giant intra-abdominal mature cystic teratoma (dermoid cyst) in an adult male, with male genitourinary tissue including prostatic and penile elements. ( 27038684 )
2016
50
Mature Cystic Teratoma with Co-existent Mucinous Cystadenocarcinoma in the same Ovary-A Diagnostic Dilemma. ( 28208869 )
2016

Variations for Cystic Teratoma

Expression for Cystic Teratoma

Search GEO for disease gene expression data for Cystic Teratoma.

Pathways for Cystic Teratoma

Pathways related to Cystic Teratoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.46 ENO2 GFAP NKX2-1 SYP

GO Terms for Cystic Teratoma

Cellular components related to Cystic Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.8 GFAP KRT20 KRT7

Biological processes related to Cystic Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament organization GO:0045109 8.96 GFAP KRT20
2 maintenance of gastrointestinal epithelium GO:0030277 8.62 MUC2 MUC6

Sources for Cystic Teratoma

3 CDC
7 CNVD
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10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
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47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
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67 TGDB
68 Tocris
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70 UMLS via Orphanet
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