MCID: CYS018
MIFTS: 52

Cystitis malady

Categories: Nephrological diseases

Aliases & Classifications for Cystitis

Aliases & Descriptions for Cystitis:

Name: Cystitis 12 52 42 14 69
Infective Cystitis 69

Classifications:



External Ids:

Disease Ontology 12 DOID:1679
ICD10 33 N30 N30.9
ICD9CM 35 595 595.9
MeSH 42 D003556
NCIt 47 C26738
UMLS 69 C0010692

Summaries for Cystitis

MalaCards based summary : Cystitis, also known as infective cystitis, is related to pyelonephritis and splenic marginal zone lymphoma. An important gene associated with Cystitis is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Influenza A and NF-KappaB Family Pathway. The drugs Hyaluronic acid and Acetylcholine have been mentioned in the context of this disorder. Affiliated tissues include kidney, prostate and bone, and related phenotypes are behavior/neurological and cardiovascular system

Wikipedia : 71 A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects... more...

Related Diseases for Cystitis

Diseases in the Cystitis family:

Acute Cystitis Chronic Cystitis

Diseases related to Cystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 312)
id Related Disease Score Top Affiliating Genes
1 pyelonephritis 30.3 CRP CXCL8 TNF
2 splenic marginal zone lymphoma 29.3 CXCL8 IL6 TNF
3 rheumatoid arthritis 29.2 CRP CXCL8 IL6 PTGS2 TLR4 TNF
4 collagenous colitis 28.9 CRP CXCL8 IL6 PTGS2 TLR4 TNF
5 interstitial cystitis 12.4
6 acute cystitis 12.3
7 hemorrhagic cystitis 12.2
8 eosinophilic cystitis 12.2
9 radiation cystitis 12.1
10 chronic cystitis 12.1
11 chronic interstitial cystitis 12.0
12 acute gonococcal cystitis 12.0
13 glandular cystitis 12.0
14 cystitis cystica 11.9
15 diphtheritic cystitis 11.9
16 urinary schistosomiasis 11.3
17 bladder disease 11.3
18 urethral syndrome 11.2
19 bacteriuria 11.1
20 pelvic lipomatosis 11.1
21 chronic pain 11.1
22 bladder tuberculosis 11.1
23 premature menopause 10.3 CRP EGF IL6
24 fallopian tube serous adenocarcinoma 10.3 CRP CXCL8 IL6
25 mixed mineral dust pneumoconiosis 10.3 CRP CXCL8 IL6
26 allergic bronchopulmonary aspergillosis 10.3 CRP CXCL8 IL6
27 secretory diarrhea myopathy and deafness 10.3 CRP IL6 KNG1
28 larynx leiomyoma 10.3 CXCL8 IL6 TLR4
29 lateral cystocele 10.3 CXCL8 IL6 TLR4
30 generalized epilepsy with febrile seizures plus 10.2 NGF TAC1 TRPV1
31 appendiceal l-cell glucagon-like peptide producing tumor 10.2 CRP CXCL8 TLR4
32 systolic heart failure 10.2 CRP UMOD UPK3A
33 testicular leydig cell tumor 10.2 NGF TAC1 TRPV1
34 hidradenitis 10.2 CRP CXCL8 PTGS2
35 vps11-related autosomal recessive hypomyelinating leukodystrophy 10.2 IL6 TNF
36 inhalation anthrax 10.2 CRP TAC1 TRPV1
37 malignant renovascular hypertension 10.2 NGF TAC1
38 gait apraxia 10.2 CRP IL6 TLR4
39 coloboma of iris 10.2 CRP IL6
40 eyelid neoplasm 10.2 CXCL8 TAC1 TRPV1
41 thymic neuroendocrine carcinoma 10.2 CXCL8 IL6 TNF
42 esophagus lymphoma 10.2 CXCL8 IL6 TNF
43 acute necrotizing encephalitis 10.2 HBEGF PTGS2 UMOD
44 trichomalacia 10.2 CXCL8 IL6 TNF
45 gastric dilatation 10.2 CXCL8 IL6 TNF
46 orthostatic proteinuria 10.2 CXCL8 IL6 TNF
47 erb-duchenne and dejerine-klumpke palsies 10.2 CXCL8 IL6 TNF
48 mandibular cancer 10.2 CXCL8 PTGS2 TRPV1
49 unilateral multicystic dysplastic kidney 10.2 CRP IL6 TNF
50 swine influenza 10.2 CRP IL6 TNF

Comorbidity relations with Cystitis via Phenotypic Disease Network (PDN): (show all 32)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Alzheimer Disease
Bladder Neck Obstruction Bronchitis
Chronic Kidney Failure Chronic Myocardial Ischemia
Decubitus Ulcer Deficiency Anemia
Esophagitis Familial Atrial Fibrillation
Generalized Atherosclerosis Heart Disease
Hydronephrosis Hypertension, Essential
Hypothyroidism Iron Deficiency Anemia
Ischemic Heart Disease Neurogenic Bladder
Osteoporosis Paralytic Ileus
Parkinson Disease, Late-Onset Prostatic Hypertrophy
Protein-Energy Malnutrition Pyelonephritis
Radiation Cystitis Schizophreniform Disorder
Transient Cerebral Ischemia Urethral Stricture
Urethritis Urinary Bladder Cancer

Graphical network of the top 20 diseases related to Cystitis:



Diseases related to Cystitis

Symptoms & Phenotypes for Cystitis

MGI Mouse Phenotypes related to Cystitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10 HBEGF IL6 NGF P2RX3 PTGS2 TAC1
2 cardiovascular system MP:0005385 9.9 IL6 NGF P2RX3 PTGS2 TAC1 TACR1
3 integument MP:0010771 9.73 CKAP4 EGF HBEGF IL6 NGF P2RX3
4 renal/urinary system MP:0005367 9.23 FZD8 IL6 PTGS2 TAC1 TLR4 TRPV1

Drugs & Therapeutics for Cystitis

Drugs for Cystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 296)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 2 9004-61-9 53477741 24759
2
Acetylcholine Approved Phase 4,Phase 2,Phase 1,Early Phase 1 51-84-3 187
3
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
4
Oxytocin Approved, Vet_approved Phase 4 50-56-6 439302 53477758
5
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
6
Ciprofloxacin Approved, Investigational Phase 4,Phase 3 85721-33-1 2764
7
Nitrofurantoin Approved, Vet_approved Phase 4,Phase 2 67-20-9 5353830
8
Acetaminophen Approved Phase 4,Phase 2 103-90-2 1983
9
Cycloserine Approved Phase 4 68-41-7 401 6234
10
Levofloxacin Approved, Investigational Phase 4,Phase 3 100986-85-4 149096
11
Ofloxacin Approved Phase 4,Phase 3 82419-36-1 4583
12
Cefotaxime Approved Phase 4 63527-52-6 456256 5742673
13
Cefoxitin Approved Phase 4 35607-66-0 441199
14
Cilastatin Approved Phase 4 82009-34-5 5280454 6435415
15
Imipenem Approved Phase 4 74431-23-5 104838
16
Fosfomycin Approved Phase 4 23155-02-4 446987
17
Lornoxicam Approved Phase 4 70374-39-9 5282204
18
Piroxicam Approved, Investigational Phase 4 36322-90-4 5280452 54676228
19
Morphine Approved, Investigational Phase 4 57-27-2 5288826
20
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
21
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
22 Adjuvants, Immunologic Phase 4,Phase 2,Phase 1
23 Protective Agents Phase 4,Phase 3,Phase 2,Early Phase 1
24 Viscosupplements Phase 4,Phase 2
25 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
26 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
27 Gentamicins Phase 4,Phase 2
28 Pharmaceutical Solutions Phase 4,Phase 2,Phase 1
29 Anticoagulants Phase 4,Phase 2,Phase 1
30 Pentosan Sulfuric Polyester Phase 4
31 abobotulinumtoxinA Phase 4,Phase 2,Phase 1,Early Phase 1
32 Botulinum Toxins Phase 4,Phase 2,Phase 1,Early Phase 1
33 Botulinum Toxins, Type A Phase 4,Phase 2,Phase 1,Early Phase 1
34 Cholinergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
35 incobotulinumtoxinA Phase 4,Phase 2,Phase 1,Early Phase 1
36 Neuromuscular Agents Phase 4,Phase 2,Phase 1,Early Phase 1
37 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
38 onabotulinumtoxinA Phase 4,Phase 2,Phase 1,Early Phase 1
39 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
40 Central Nervous System Depressants Phase 4,Phase 3,Phase 2
41 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1
42 Renal Agents Phase 4,Phase 3,Phase 2,Phase 1
43 Antimetabolites Phase 4,Phase 3,Phase 2
44 Adrenergic Agents Phase 4,Phase 3
45 Adrenergic Agonists Phase 4,Phase 3
46 Adrenergic alpha-2 Receptor Agonists Phase 4
47 Adrenergic alpha-Agonists Phase 4
48 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
49 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1
50 Anti-Anxiety Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 223)
id Name Status NCT ID Phase
1 Efficacy of Combined Intravesical Therapy With Hyaluronic Acid and Chondroitin Sulphate in the Treatment of Recurrent Cystitis Refractory to Escherichia Coli Extract Unknown status NCT02366676 Phase 4
2 Gentamicin Bladder Instillation Trial Unknown status NCT01884467 Phase 4
3 Functional Electrical Stimulation-Assisted Walking: Reduction of Secondary Complications Due to Spinal Cord Injury Unknown status NCT00201968 Phase 4
4 Efficacy Study of Pentosan Polysulfate Sodium,Hydrodistension and Combination Therapy for Bladder Pain Syndrome Unknown status NCT01895153 Phase 4
5 Botulinum A Toxin in the Treatment of Patients With Painful Bladder Syndrome Unknown status NCT01157507 Phase 4
6 Usefulness of Dexmedetomidine on Post-operative Pain Management in Patients With Interstitial Cystitis Completed NCT01195116 Phase 4
7 Intranasal Oxytocin for the Treatment of Pain Associated With Interstitial Cystitis Completed NCT00919802 Phase 4
8 Intranasal Ketorolac Tromethamine (Sprix) for Acute Pain of Interstitial Cystitis Flare of Pain Completed NCT02000401 Phase 4
9 Botox as a Treatment for Interstitial Cystitis in Women Completed NCT00194610 Phase 4
10 Management of Urinary Tract Infections in Primary Care Facilities. Completed NCT01132131 Phase 4
11 A Pilot Comparison of Short-course Nitrofurantoin in Females With Uncomplicated Bacterial Cystitis in the Emergency Department Completed NCT01749605 Phase 4
12 Treating Urological Chronic Pelvic Pain Syndrome (UCPPS) Pain Completed NCT02385266 Phase 4
13 A Safety and Efficacy Study of Doripenem in Participants With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Urinary Tract Infections Completed NCT00965848 Phase 4
14 Intravesicular Onabotulinumtoxin A in Interstitial Cystitis Recruiting NCT02297100 Phase 4
15 Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome Recruiting NCT01312259 Phase 4
16 Evaluation of the Non-inferiority of Cefoxitin Versus Imipenem/Cilastatin in the Treatment of Urinary Tract Infections Caused by ESBL-producing Escherichia Coli Recruiting NCT02474706 Phase 4
17 Chronic Pain Risk Associated With Menstrual Period Pain Recruiting NCT02214550 Phase 4
18 Study Comparing Nitrofurantoin to Fosfomycin for Acute Urinary Tract Infection in Women Active, not recruiting NCT01966653 Phase 4
19 Solifenacin, Levofloxacin or Lornoxicam, Which Is Ideal for Management of Intravesical Instillation BCG Side Effects? Active, not recruiting NCT03038321 Phase 4
20 Reduction of Bladder Injection Pain With Belladonna Opiate Suppository Enrolling by invitation NCT02600715 Phase 4
21 Effectiveness and Safety Study of Pentosan Polysulfate Sodium for the Treatment of Interstitial Cystitis Terminated NCT00086684 Phase 4
22 Efficacy of Gralise® for Chronic Pelvic Pain Terminated NCT01678911 Phase 4
23 The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study Terminated NCT00164099 Phase 4
24 Trial of Viagra' in Men With Chronic Pelvic Pain Syndrome Type III Terminated NCT00194597 Phase 4
25 Chronic Bladder Pain Syndrome in Women: Can Doxycycline Help? A Prospective Study Terminated NCT01879930 Phase 4
26 Nitrofurantoin Macrocrystals 3 Days Versus 7 Days in the Treatment of Women With Uncomplicated Cystitis Withdrawn NCT00361998 Phase 4
27 Acupuncture for the Treatment of Interstitial Cystitis (IC) Symptoms Unknown status NCT00094874 Phase 3
28 Comparison of Cy-Atg vs Flu-Atg for the Conditioning Therapy in Allo-HCT for Adult Aplastic Anemia Unknown status NCT01145976 Phase 3
29 Efficacy Study of Adalimumab to Treat Interstitial Cystitis Completed NCT01295814 Phase 3
30 Omalizumab in Interstitial Cystitis/Bladder Pain Syndrome Completed NCT01294878 Phase 3
31 URACYST® For the Treatment of GAG Deficient Interstitial Cystitis Completed NCT00150488 Phase 2, Phase 3
32 Efficacy and Safety of Cefditoren Pivoxil Versus Ciprofloxacin in Acute Uncomplicated Cystitis Completed NCT00598403 Phase 3
33 Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS) Completed NCT00124306 Phase 3
34 D Mannose in Recurrent Urinary Tract Infections Completed NCT01808755 Phase 3
35 A Comparison of the Effectiveness and Safety of Levofloxacin to That of Ciprofloxacin in Treating Complicated Urinary Tract Infection and Acute Pyelonephritis. Completed NCT00210886 Phase 3
36 A Pilot Study of the Effects of Mirabegron on Symptoms in Patients With Interstitial Cystitis Recruiting NCT02787083 Phase 3
37 Radiation Induced Cystitis Treated With Hyperbaric Oxygen - A Randomized Controlled Trial Recruiting NCT01659723 Phase 2, Phase 3
38 Efficacy and Safety of 2 Doses of AQX-1125 in Subjects With Interstitial Cystitis / Bladder Pain Syndrome Recruiting NCT02858453 Phase 3
39 A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression Recruiting NCT02497287 Phase 3
40 Cyclophosphamide for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Recruiting NCT02460588 Phase 3
41 Pilot Study Evaluating the Efficacy of Certolizumab Pegol for Interstitial Cystitis Active, not recruiting NCT02497976 Phase 3
42 A Randomized Multicenter Double-Blind CT to Evaluate the Efficacy and Safety of Mycophenolate Mofetil . . . Terminated NCT00451867 Phase 3
43 Efficacy of Antimicrobial Prophylaxis for Shock Wave Lithotripsy (SWL) on Reducing Urinary Tract Infection (UTI) Terminated NCT01873690 Phase 3
44 Study to Determine if Hyperbaric Oxygen Therapy is Helpful for Treating Radiation Tissue Injuries Terminated NCT00134628 Phase 3
45 Chemotherapy With or Without Total-Body Irradiation Prior to Bone Marrow Transplantation in Treating Children With Acute Lymphoblastic Leukemia Terminated NCT00002961 Phase 3
46 Comparison in the Treatment of Acute Cystitis Using Cephalosporin and Norfloxacin (CECI) Withdrawn NCT01527019 Phase 3
47 Efficacy of Botulinum Toxin Type A in Patients With Bladder Pain Syndrome/Intersticial Cystitis and Hunners' Lesions Unknown status NCT01437579 Phase 2
48 A Double Blind Randomized Study Using Placenta Derived Decidual Stromal Cells for Hemorrhagic Cystitis Unknown status NCT02174536 Phase 2
49 Effect of Adjuvant Treatment With Compound Cranberry Extract Tablets in Acute Bacterial Cystitis. Unknown status NCT00305071 Phase 2
50 Cyclosporine in Interstitial Cystitis: Efficacy, Safety and Mechanism of Action Completed NCT01990898 Phase 2

Search NIH Clinical Center for Cystitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: cystitis

Genetic Tests for Cystitis

Anatomical Context for Cystitis

MalaCards organs/tissues related to Cystitis:

39
Kidney, Prostate, Bone, Bone Marrow, Testes, Endothelial, Spinal Cord

Publications for Cystitis

Articles related to Cystitis:

(show top 50) (show all 1251)
id Title Authors Year
1
Transurethral Resection Alone Vs Resection Combined With Therapeutic Hydrodistention as Treatment for Ulcerative Interstitial Cystitis: Initial Experience With Propensity Score Matching Studies. ( 27720770 )
2017
2
Emphysematous Cystitis and Infectious Exacerbation of COPD. A Highly Unusual Finding. ( 28069294 )
2017
3
Fulranumab in patients with interstitial cystitis/bladder pain syndrome: observations from a randomized, double-blind, placebo-controlled study. ( 28056917 )
2017
4
Preferential Use of Nitrofurantoin Over Fluoroquinolones for Acute Uncomplicated Cystitis and Outpatient Escherichia coli Resistance in an Integrated Healthcare System. ( 28052786 )
2017
5
Re: Heparin and Alkalinized Lidocaine versus Alkalinized Lidocaine for Treatment of Interstitial Cystitis Symptoms. ( 27979536 )
2017
6
BKV-specific T-cells in the treatment of severe refractory haemorrhagic cystitis after HLA-haploidentical haematopoietic cell transplantation. ( 28083990 )
2017
7
Revisiting the Role of Potassium Sensitivity Testing and Cystoscopic Hydrodistention for the Diagnosis of Interstitial Cystitis. ( 26999787 )
2016
8
Clinical phenotyping does not differentiate Hunner's lesion subtype of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS): A relook at the role of cystoscopy. ( 27117441 )
2016
9
A Phase II Study of Efficacy and Safety of a Novel, Oral SHIP1 Activator, AQX-1125, in Subjects with Moderate to Severe Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS). ( 26968644 )
2016
10
Studies of human polyomaviruses, with HPyV7, BKPyV, and JCPyV present in urine of allogeneic hematopoietic stem cell transplanted patients with or without hemorrhagic cystitis. ( 26809742 )
2016
11
Evidence for the Role of Mast Cells in Cystitis-Associated Lower Urinary Tract Dysfunction: A Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network Animal Model Study. ( 28002455 )
2016
12
Benefits of Preventive Administration of Chlorella sp. on Visceral Pain and Cystitis Induced by a Single Administration of Cyclophosphamide in Female Wistar Rat. ( 27152976 )
2016
13
Re: Yildiz et al: Evaluation of Hyperbaric Oxygen Therapy in the Treatment of Radiation-induced Hemorrhagic Cystitis (Urology 2016;doi:10.1016/j.urology.2016.05.063). ( 27369819 )
2016
14
Protective Effect of Intravesical Platelet-Rich Plasma on Cyclophosphamide-Induced Hemorrhagic Cystitis. ( 27917814 )
2016
15
Sensory hyperinnervation distinguishes bladder pain syndrome/interstitial cystitis from overactive bladder syndrome. ( 27378135 )
2016
16
Incidence of sterile hemorrhagic cystitis in tumor-bearing dogs concurrently treated with oral metronomic cyclophosphamide chemotherapy and furosemide: 55 cases (2009-2015). ( 27901449 )
2016
17
Eosinophilic cystitis and haematuria: Case report of a rare disease and common presentation. ( 27179336 )
2016
18
Differences in Urodynamic Parameters between Women with Interstitial Cystitis/Bladder Pain Syndrome and Severe Overactive Bladder. ( 27130264 )
2016
19
Intravesical treatment for interstitial cystitis/painful bladder syndrome: a network meta-analysis. ( 27614759 )
2016
20
The Acute Cystitis Symptom Score for Patient-Reported Outcome Assessment. ( 27591987 )
2016
21
Hydrodistention of the bladder for the treatment of bladder pain syndrome/interstitial cystitis (BPS/IC). ( 27092957 )
2016
22
Study of the apoptotic effect of urine as a diagnostic biomarker in patients with interstitial cystitis. ( 27174573 )
2016
23
Efficacy and safety of botulinum toxin injection for interstitial cystitis/bladder pain syndrome: a systematic review and meta-analysis. ( 27139498 )
2016
24
A Phase II Clinical Trial Evaluating the Preventive Effectiveness of Lactobacillus Vaginal Suppositories in Patients with Recurrent Cystitis. ( 27549677 )
2016
25
Re: Fibrin Glue Therapy for Severe Hemorrhagic Cystitis after Allogeneic Hematopoietic Stem Cell Transplantation. ( 26887714 )
2016
26
Acute cystitis caused by commensal Neisseria oralis: A case report and review of the literature. ( 27889997 )
2016
27
Differential Expression of Renal Outer Medullary K(+) Channel and Voltage-gated K(+) Channel 7.1 in Bladder Urothelium of Patients With Interstitial Cystitis/Painful Bladder Syndrome. ( 27856205 )
2016
28
Risk Factors Associated with Severity and Outcomes in Pediatric Patients with Hemorrhagic Cystitis. ( 26926552 )
2016
29
Urothelial Functional Protein and Sensory Receptors in Patients with Interstitial Cystitis/Bladder Pain Syndrome with and Without Hunner's Lesion. ( 27575016 )
2016
30
Elevated level of nerve growth factor in the bladder pain syndrome/interstitial cystitis: a meta-analysis. ( 27462520 )
2016
31
Interstitial cystitis: Another rotation of the kaleidoscope of autoimmunity? ( 27235121 )
2016
32
Remarks about the study of eosinophilic cystitis and idiopathic hyper-eosinophilic syndrome in a eight-year-old girl. ( 27215264 )
2016
33
A case of BK virus nephropathy without hemorrhagic cystitis after hematopoietic stem cell transplantation. ( 27278550 )
2016
34
Re: A Novel Approach for the Treatment of Radiation-Induced Hemorrhagic Cystitis with the GreenLighta8c XPS Laser. ( 27597093 )
2016
35
The Role of Immunoglobulin E in the Pathogenesis of Ketamine Related Cystitis and Ulcerative Interstitial Cystitis: An Immunohistochemical Study. ( 27228524 )
2016
36
Pregnancy With a Successful Vaginal Delivery Following Augmentation Enterocystoplasty for Ketamine Cystitis: A Case Report. ( 28043107 )
2016
37
Long-term outcomes of intravesical dimethyl sulfoxide/heparin/hydrocortisone therapy for interstitial cystitis/bladder pain syndrome. ( 27987022 )
2016
38
Evaluating the Role of Urinalysis for Suspected Cystitis in Women Undergoing Pelvic Radiotherapy. ( 27101588 )
2016
39
CUA guideline: Diagnosis and treatment of interstitial cystitis/bladder pain syndrome. ( 27790294 )
2016
40
Stool-based biomarkers of interstitial cystitis/bladder pain syndrome. ( 27188581 )
2016
41
Hemostatic Efficacy and Histopathological Effects of Ankaferd Blood Stopper(Ar) in an Experimental Rat Model of Cyclophosphamide-Induced Hemorrhagic Cystitis. ( 27215482 )
2016
42
F16357, a novel PAR1 antagonist improves urodynamic parameters in a rat model of Interstitial Cystitis. ( 27111354 )
2016
43
Urologic Outcomes of Children With Hemorrhagic Cystitis After Bone Marrow Transplant at a Single Institution. ( 27793653 )
2016
44
Protective Effect of Intravesical Platelet-Rich Plasma on Cyclophosphamide-Induced Hemorrhagic Cystitis. ( 27917804 )
2016
45
Urinary alkalisers for cystitis-fact or fiction? ( 27977660 )
2016
46
Prevalence of antibiotic susceptibility and resistance of Escherichia coli in acute uncomplicated cystitis in Korea: Systematic review and meta-analysis. ( 27603359 )
2016
47
Bladder Distension Increases Blood Flow in Pain-Related Brain Structures in Subjects With Interstitial Cystitis. ( 27018508 )
2016
48
Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis. ( 27995963 )
2016
49
Challenges and Opportunities in Radiation-induced Hemorrhagic Cystitis. ( 27601964 )
2016
50
Protective Effect of Thymoquinone against Cyclophosphamide-Induced Hemorrhagic Cystitis through Inhibiting DNA Damage and Upregulation of Nrf2 Expression. ( 27489498 )
2016

Variations for Cystitis

Expression for Cystitis

Search GEO for disease gene expression data for Cystitis.

Pathways for Cystitis

Pathways related to Cystitis according to GeneCards Suite gene sharing:

(show all 34)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.75 CXCL8 IL6 TACR1 TLR4 TNF
2
Show member pathways
12.64 EGF IL6 NGF TLR4 TNF
3 12.61 CXCL8 EGF FZD8 IL6 PTGS2
4
Show member pathways
12.28 CRP IL6 PTGS2 TNF
5
Show member pathways
12.28 CXCL8 IL6 PTGS2 TNF
6 12.25 FZD8 HBEGF TLR4 TNF
7
Show member pathways
12.2 CXCL8 IL6 TLR4 TNF
8
Show member pathways
12.17 CXCL8 IL6 PTGS2 TLR4 TNF
9
Show member pathways
12.11 CXCL8 IL6 TLR4 TNF
10
Show member pathways
12.04 EGF FZD8 HBEGF IL6
11 11.95 EGF FZD8 IL6 PTGS2 TLR4 TNF
12 11.92 CXCL8 IL6 PTGS2 TNF
13 11.85 CXCL8 IL6 NGF TAC1 TACR1 TNF
14 11.83 CXCL8 IL6 TLR4 TNF
15 11.82 CXCL8 PTGS2 TLR4 TNF
16 11.78 CXCL8 IL6 TLR4 TNF
17 11.77 CXCL8 IL6 TLR4
18
Show member pathways
11.71 CXCL8 PTGS2 TNF
19 11.69 CXCL8 IL6 TLR4 TNF
20 11.66 IL6 TLR4 TNF
21 11.66 CXCL8 EGF HBEGF UPK3A
22 11.62 CXCL8 HBEGF IL6
23 11.56 CXCL8 EGF IL6 TNF
24
Show member pathways
11.53 CXCL8 IL6 PTGS2 TNF
25 11.51 CXCL8 IL6 PTGS2 TACR1 TLR4 TNF
26 11.49 CXCL8 IL6 PTGS2
27 11.48 HBEGF IL6 TNF
28 11.45 CXCL8 IL6 TLR4 TNF
29 11.44 IL6 KNG1 TNF
30 11.36 CXCL8 IL6 PTGS2 TNF
31 11.31 CXCL8 IL6 TLR4 TNF
32 11.29 IL6 TLR4 TNF
33 10.46 TAC1 TACR1
34 10.3 CRP CXCL8 IL6 PTGS2 TNF

GO Terms for Cystitis

Cellular components related to Cystitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.97 CKAP4 EGF FZD8 HBEGF KNG1 P2RX3
2 extracellular space GO:0005615 9.56 CRP CXCL8 EGF HBEGF IL6 KNG1
3 extracellular region GO:0005576 9.32 CRP CXCL8 EGF HBEGF IL6 KNG1

Biological processes related to Cystitis according to GeneCards Suite gene sharing:

(show all 38)
id Name GO ID Score Top Affiliating Genes
1 angiogenesis GO:0001525 9.96 CXCL8 EGF FZD8 PTGS2
2 positive regulation of apoptotic process GO:0043065 9.93 IL6 KNG1 NGF PTGS2 TNF TRPV1
3 response to lipopolysaccharide GO:0032496 9.92 IL6 PTGS2 TAC1 TLR4
4 positive regulation of protein kinase B signaling GO:0051897 9.85 HBEGF IL6 TNF
5 positive regulation of cytosolic calcium ion concentration GO:0007204 9.85 KNG1 TAC1 TACR1 TRPV1
6 cellular response to lipopolysaccharide GO:0071222 9.84 CXCL8 IL6 TLR4 TNF
7 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.83 IL6 PTGS2 TNF
8 response to glucocorticoid GO:0051384 9.83 IL6 PTGS2 TNF
9 defense response to Gram-positive bacterium GO:0050830 9.82 CRP IL6 TNF
10 regulation of blood pressure GO:0008217 9.82 PTGS2 TAC1 TACR1
11 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 9.81 IL6 NGF PTGS2
12 positive regulation of interleukin-6 production GO:0032755 9.75 IL6 TLR4 TNF
13 positive regulation of smooth muscle cell proliferation GO:0048661 9.73 HBEGF IL6 PTGS2 TNF
14 positive regulation of NF-kappaB import into nucleus GO:0042346 9.69 PTGS2 TLR4 TNF
15 positive regulation of renal sodium excretion GO:0035815 9.68 TAC1 TACR1
16 positive regulation of synaptic transmission, GABAergic GO:0032230 9.67 TAC1 TACR1
17 response to auditory stimulus GO:0010996 9.67 IL6 TACR1
18 response to pain GO:0048265 9.67 TAC1 TACR1 TRPV1
19 sensory perception of pain GO:0019233 9.67 PTGS2 TAC1 TACR1 TRPV1
20 positive regulation of acute inflammatory response GO:0002675 9.65 IL6 TAC1
21 positive regulation of chemokine production GO:0032722 9.65 IL6 TLR4 TNF
22 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.63 TLR4 TNF
23 tachykinin receptor signaling pathway GO:0007217 9.63 TAC1 TACR1
24 positive regulation of action potential GO:0045760 9.62 TAC1 TACR1
25 response to heat GO:0009408 9.62 IL6 P2RX3 TACR1 TRPV1
26 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.61 IL6 TNF
27 urinary bladder smooth muscle contraction GO:0014832 9.6 P2RX3 TRPV1
28 positive regulation of synaptic transmission, cholinergic GO:0032224 9.59 TAC1 TACR1
29 positive regulation of fever generation GO:0031622 9.58 PTGS2 TNF
30 behavioral response to pain GO:0048266 9.58 P2RX3 TACR1 TRPV1
31 positive regulation of saliva secretion GO:0046878 9.57 TAC1 TACR1
32 detection of abiotic stimulus GO:0009582 9.56 TAC1 TACR1
33 smooth muscle contraction involved in micturition GO:0060083 9.52 TACR1 TRPV1
34 negative regulation of lipid storage GO:0010888 9.43 CRP IL6 TNF
35 positive regulation of nitric oxide biosynthetic process GO:0045429 9.35 IL6 PTGS2 TLR4 TNF TRPV1
36 positive regulation of lymphocyte proliferation GO:0050671 9.33 TAC1 TACR1 TLR4
37 inflammatory response GO:0006954 9.32 CRP CXCL8 IL6 KNG1 PTGS2 TAC1
38 positive regulation of gene expression GO:0010628 10 CRP IL6 NGF TLR4 TNF

Molecular functions related to Cystitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 8.92 EGF HBEGF IL6 NGF

Sources for Cystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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