MCID: CYS018
MIFTS: 51

Cystitis malady

Nephrological diseases category
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Summaries for Cystitis

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Wikipedia:65 A urinary tract infection (UTI) (also known as acute cystitis or bladder infection) is an infection that... more...

MalaCards based summary: Cystitis is related to chronic cystitis and chronic interstitial cystitis. An important gene associated with Cystitis is HBEGF (heparin-binding EGF-like growth factor), and among its related pathways is Neuroscience. The drugs mesna and carboprost and the compounds pgj-2 and hcec have been mentioned in the context of this disorder. Affiliated tissues include kidney, prostate and testes, and related mouse phenotype growth/size/body.

Aliases & Classifications for Cystitis

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 57SNOMED-CT, 27ICD9CM, 39NCIt, 34MeSH, 25ICD10
See all sources

Cystitis, Aliases & Descriptions:

Name: Cystitis 8 10 44 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


External Ids:

Disease Ontology8 DOID:1679
ICD9CM27 595, 595.9
NCIt39 C26738
MeSH34 D003556
ICD1025 N30, N30.9

Related Diseases for Cystitis

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Diseases in the Cystitis family:

Acute Cystitis Chronic Cystitis

Diseases related to Cystitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 198)
idRelated DiseaseScoreTop Affiliating Genes
1chronic cystitis31.5PTGS1, NGF
2chronic interstitial cystitis31.3TSPO, HBEGF, SPRR2G
3pyelonephritis30.9UMOD, NAGLU
4eosinophilia30.4RNASE3, NGF
5pneumonia30.1PTGS1, NAGLU
6urinary tract obstruction30.1HBEGF, NAGLU, UMOD
7chronic pyelonephritis29.9UMOD, NAGLU
8vesicoureteral reflux29.9NAGLU, UMOD
9chronic obstructive pulmonary disease29.8PTGS1, RNASE3, TSPO
10asthma29.6NGF, HBEGF, PTGS1, RNASE3, TSPO
11leukemia29.5NGF, HBEGF, PTGS1, RNASE3, GAP43
12diabetes mellitus29.5UMOD, NAGLU, NGF
13rheumatoid arthritis29.4TSPO, RNASE3, NAGLU, PTGS1, HBEGF
14eosinophilic cystitis10.9
15acute cystitis10.8
16hemorrhagic cystitis10.8
17radiation cystitis10.8
18cystitis cystica10.7
19hematopoietic stem cell transplantation10.5
20prostatitis10.5
21pyelitis10.5
22urethritis10.5
23bacteriuria10.4
24keratoconjunctivitis10.4RNASE3
25pelvic lipomatosis10.4
26lipomatosis10.4
27urethral syndrome10.3
28acute pyelonephritis10.3
29adenocarcinoma10.3
30blindness10.3
31rhinitis10.2PTGS1, RNASE3
32vernal keratoconjunctivitis10.2RNASE3, NGF
33spiradenoma10.2TSPO, NGF
34glandular cystitis10.2
35acute gonococcal cystitis10.2
36neurogenic bladder10.2
37proctitis10.2
38lupus erythematosus10.2
39angioedema10.2RNASE3, PTGS1
40respiratory failure10.2RNASE3, PTGS1
41bladder carcinoma10.2
42systemic lupus erythematosus10.2
43nephrogenic adenoma10.2
44diphtheritic cystitis10.2
45neuronitis10.2
46hydronephrosis10.2
47adenoma10.2
48tuberculosis10.2
49vaginitis10.2
50hypereosinophilic syndrome10.2

Graphical network of the top 20 diseases related to Cystitis:



Diseases related to cystitis

Symptoms for Cystitis

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Drugs & Therapeutics for Cystitis

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Drug clinical trials:

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Search NIH Clinical Center for Cystitis

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Cystitis

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Anatomical Context for Cystitis

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MalaCards organs/tissues related to Cystitis:

32
Kidney, Prostate, Testes, Bone marrow, Bone, Spinal cord, Endothelial, Colon, Skin, B cells, Pituitary, Neutrophil, Heart, Thyroid, Breast, Uterus, Cervix, T cells

Animal Models for Cystitis or affiliated genes

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MGI Mouse Phenotypes related to Cystitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053788.2GAP43, UMOD, NAGLU, PTGS1, HBEGF, NGF

Publications for Cystitis

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Articles related to Cystitis:

(show top 50)    (show all 1034)
idTitleAuthorsYear
1
SjAPgren's syndrome accompanied with interstitial cystitis: a case report and review of the literature. (24395198)
2014
2
Coexistence of inflammatory pseudotumour and pseudomembranous cystitis: a histopathological surprise. (24395867)
2014
3
Emphysematous pyelonephritis and cystitis in a renal transplant recipient. (25320257)
2014
4
Risk factors and predictors of severity score and complications of pediatric hemorrhagic cystitis. (23954584)
2014
5
Computed tomography scan in supine and prone positions: an alternative method to detect intramural gas in emphysematous cystitis and to evaluate efficacy after adjuvant continuous intravesical irrigation treatment. (23148785)
2013
6
Maintenance of the response to dimethyl sulfoxide treatment using hyperbaric oxygen in interstitial cystitis/painful bladder syndrome: a prospective, randomized, comparative study. (23485788)
2013
7
Eosinophilic cystitis presented as a manifestation of hypereosinophilic syndrome: a case report and review of the literature. (23573073)
2013
8
Interleukin-6 levels in female rats with protamine sulfate-induced chronic cystitis treated with hyaluronic acid. (23379983)
2013
9
Intravesical heparin: interstitial cystitis (painful bladder syndrome). (24421434)
2013
10
Cystectomy for ulcerative interstitial cystitis: sequelae and patients' perceptions of improvement. (24074977)
2013
11
Elimination of Hunner's Ulcers by Fulguration in Patients With Interstitial Cystitis: Is It Effective and Long Lasting? (24255759)
2013
12
Effects of Tadalafil on Hemorrhagic Cystitis and Testicular Dysfunction Induced by Cyclophosphamide in Rats. (24051982)
2013
13
Nationwide surveillance of bacterial pathogens from patients with acute uncomplicated cystitis conducted by the Japanese surveillance committee during 2009 and 2010: antimicrobial susceptibility of Escherichia coli and Staphylococcus saprophyticus. (23640203)
2013
14
A case of eosinophilic cystitis in patients with abdominal pain, dysuria, genital skin hyperemia and slight toxocariasis. (23820659)
2013
15
Ketamine cystitis: an emerging diagnostic and therapeutic challenge. (23124288)
2012
16
Impact of intravesical hyaluronic acid and chondroitin sulfate on bladder pain syndrome/interstitial cystitis. (21904840)
2012
17
Genotypic Analysis of E. coli Strains Isolated from Patients with Cystitis and Pyelonephritis. (22997556)
2012
18
Effects of CYP-induced cystitis on PACAP/VIP and receptor expression in micturition pathways and bladder function in mice with overexpression of NGF in urothelium. (22700375)
2012
19
Urinary tract analgesics for the treatment of patients with acute cystitis: where is the clinical evidence? (23030327)
2012
20
Effects of intravesical dexpanthenol use on lipid peroxidation and bladder histology in a chemical cystitis animal model. (22546378)
2012
21
Mapping of pain phenotypes in female patients with bladder pain syndrome/interstitial cystitis and controls. (22633363)
2012
22
Polyomavirus BK: possibly associated skin eruption in a patient with hemorrhagic cystitis. (21276065)
2011
23
Clinical features of lupus cystitis complicated with hydroureteronephrosis in a Chinese population. (21239742)
2011
24
Editorial comment to effect of hyaluronic acid on urine nerve growth factor in cyclophosphamide-induced cystitis. (21699581)
2011
25
AUA guideline for the diagnosis and treatment of interstitial cystitis/bladder pain syndrome. (21497847)
2011
26
Sickness behaviors in response to unusual external events in healthy cats and cats with feline interstitial cystitis. (21194324)
2011
27
Trimethoprim-sulfamethoxazole may no longer be acceptable for the treatment of acute uncomplicated cystitis in the United States. (21765092)
2011
28
Eosinophilic cystitis associated with eosinophilic enterocolitis: case reports and review of the literature. (20505026)
2010
29
Penicillin G-induced hemorrhagic cystitis with hydronephrosis. (19755771)
2009
30
CXCL10 blockade protects mice from cyclophosphamide-induced cystitis. (18957084)
2008
31
CD34+ fibrocytes in chronic cystitis and noninvasive and invasive urothelial carcinomas of the urinary bladder. (17149610)
2007
32
Is there a relation between urinary interleukin-6 levels and symptoms before and after intra-vesical glycosaminoglycan substitution therapy in patients with bladder pain syndrome/interstitial cystitis? (17982709)
2007
33
Uronate peaks and urinary hyaluronic acid levels correlate with interstitial cystitis severity. (16890679)
2006
34
Giant botryoid fibroepithelial polyp of bladder with myofibroblastic stroma and cystitis cystica et glandularis. (12574920)
2003
35
Bladder neck obstruction due to bilharzial cystitis as a cause of renal failure in Aden City. (14612029)
2003
36
Antibiotic treatment for five days is effective in children with acute cystitis. (11883819)
2002
37
Eosinophilic cystitis in adults. (11176473)
2001
38
Eosinophilic cystitis in view of two cases. (10935134)
1999
39
Eosinophilic cystitis following an infected urachal remnant. (10369914)
1999
40
Fluoroquinolone use for acute cystitis in an IPA-model managed care organization. (8601266)
1995
41
Eosinophilic cystitis caused by vesical sparganosis: a case report. (8437270)
1993
42
Cyclophosphamide-induced hemorrhagic pyelitis and ureteritis associated with cystitis in marrow transplantation. (2231904)
1990
43
Vaginal discharge and cystitis. (3399160)
1988
44
Urinary tract infection during pregnancy. Asymptomatic bacteriuria, acute cystitis, and acute pyelonephritis. (6374641)
1984
45
Single dose trimethoprim-sulfamethoxazole in acute cystitis. (6413899)
1983
46
A new citrated formulation of nalidixic acid (Mictral U.K.) for the treatment of acute cystitis. (7016625)
1981
47
Chronic interstitial cystitis. (5159574)
1971
48
Psychometric testing with the human figure drawing in chronic cystitis. (5532923)
1970
49
Surgical treatment of chronic cystitis in a bitch. (5812943)
1969
50
Remarks on a New Mode of Affording Permanent Relief to Intractable Chronic Cystitis, and to Confirmed Prostatic Retention of Urine. (20750395)
1882

Variations for Cystitis

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Expression for genes affiliated with Cystitis

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Expression patterns in normal tissues for genes affiliated with Cystitis

Search GEO for disease gene expression data for Cystitis.

Pathways for genes affiliated with Cystitis

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Pathways related to Cystitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4GAP43, PTGS1, NGF

Compounds for genes affiliated with Cystitis

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Compounds related to Cystitis according to GeneCards/GeneDecks:

(show top 50)    (show all 78)
idCompoundScoreTop Affiliating Genes
1pgj-24410.2NGF, PTGS1
2hcec4410.1HBEGF, NGF
3lte44410.1PTGS1, RNASE3
411-dehydrothromboxane b24410.1PTGS1, RNASE3
5zafirlukast44 28 1112.1RNASE3, PTGS1
6calcium oxalate449.9NAGLU, UMOD
7eszopiclone44 1110.9PTGS1, TSPO
8zopiclone44 1110.9PTGS1, TSPO
9oxalate449.9NAGLU, UMOD
10montelukast44 50 28 1112.8PTGS1, RNASE3
11zolpidem28 44 24 1112.8TSPO, PTGS1
12diphenhydramine44 28 2 24 1113.8TSPO, PTGS1
13zymosan449.7NAGLU, RNASE3
14phorbol449.7HBEGF, RNASE3, GAP43
15choline44 24 1111.7NGF, PTGS1, GAP43
16sulfate44 2410.7UMOD, NAGLU, HBEGF
17latex449.6RNASE3, NAGLU, HBEGF
18txb2449.6RNASE3, NAGLU, PTGS1
19aspirin44 50 28 2412.6NGF, PTGS1, RNASE3
20uric acid44 2410.6NAGLU, RNASE3, UMOD
21urea44 24 1111.5UMOD, RNASE3, NAGLU
22theophylline44 28 24 1112.5TSPO, RNASE3, NGF
23hyaluronic acid44 2410.5RNASE3, NAGLU, PTGS1
24polysaccharide449.5UMOD, RNASE3, HBEGF, NGF
25vitamin a44 24 1111.4GAP43, NAGLU, HBEGF
26cocaine44 1110.4GAP43, TSPO, NGF
27ltc4449.4RNASE3, PTGS1
28agar449.4TSPO, PTGS1, HBEGF
2912-o-tetradecanoylphorbol 13-acetate449.4GAP43, HBEGF, NGF
30cycloheximide449.4GAP43, PTGS1, HBEGF, NGF
31n acetylcysteine449.3RNASE3, NAGLU, HBEGF
32vegf449.2RNASE3, PTGS1, HBEGF, NGF
33isoflurane50 44 1111.2TSPO, NAGLU
34dbc-amp449.2NGF, NAGLU, RNASE3, GAP43
35indomethacin44 28 61 1112.2NGF, PTGS1, TSPO
36nmda44 2810.2NGF, PTGS1, TSPO, GAP43
37acetylcholine44 50 28 24 1113.1NGF, RNASE3, TSPO, GAP43
38dexamethasone44 50 28 1112.1NGF, HBEGF, PTGS1, RNASE3, GAP43
39cyclosporin a44 28 6111.0NGF, NAGLU, RNASE3, TSPO
40valproic acid44 50 24 1112.0PTGS1, NAGLU, TSPO, GAP43
41dopamine44 28 24 1112.0NGF, NAGLU, TSPO, GAP43
42alanine448.9NGF, HBEGF, PTGS1, NAGLU, GAP43
43nitric oxide44 24 1110.9GAP43, RNASE3, NAGLU, PTGS1, HBEGF
44heparin44 28 24 1111.9HBEGF, NAGLU, RNASE3, UMOD, GAP43
45glutamate448.9GAP43, TSPO, PTGS1, HBEGF, NGF
46steroid448.7NAGLU, RNASE3, TSPO, GAP43
47creatinine448.7NGF, NAGLU, RNASE3, TSPO, UMOD
48cysteine448.6NGF, HBEGF, PTGS1, NAGLU, UMOD, GAP43
49calcium44 50 24 1111.4NGF, HBEGF, NAGLU, RNASE3, UMOD, GAP43
50h2o2448.3GAP43, TSPO, RNASE3, NAGLU, PTGS1, HBEGF

GO Terms for genes affiliated with Cystitis

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Products for genes affiliated with Cystitis

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Sources for Cystitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet