MCID: CYT018
MIFTS: 13

Cytochrome P450 2d6 Variant

Categories: Rare diseases

Aliases & Classifications for Cytochrome P450 2d6 Variant

MalaCards integrated aliases for Cytochrome P450 2d6 Variant:

Name: Cytochrome P450 2d6 Variant 49
Human Cytochrome P450 2d6 49
Cytochrome P450 49
Cyp2d6 49

Classifications:



Summaries for Cytochrome P450 2d6 Variant

MalaCards based summary : Cytochrome P450 2d6 Variant, also known as human cytochrome p450 2d6, is related to cytochrome p450 oxidoreductase deficiency and disordered steroidogenesis due to cytochrome p450 oxidoreductase deficiency. Affiliated tissues include liver.

Wikipedia : 72 Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene. CYP2D6 is... more...

Related Diseases for Cytochrome P450 2d6 Variant

Diseases related to Cytochrome P450 2d6 Variant via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 125)
# Related Disease Score Top Affiliating Genes
1 cytochrome p450 oxidoreductase deficiency 12.6
2 disordered steroidogenesis due to cytochrome p450 oxidoreductase deficiency 12.6
3 aromatase deficiency 11.6
4 antley-bixler syndrome with genital anomalies and disordered steroidogenesis 11.5
5 anxiety 11.4
6 autoimmune hepatitis 11.3
7 neuroleptic malignant syndrome 11.3
8 major depressive disorder 11.3
9 schizophrenia 11.3
10 basal cell carcinoma 11.3
11 substance abuse 11.3
12 multiple chemical sensitivity 11.3
13 tardive dyskinesia 11.2
14 serotonin syndrome 11.2
15 obsessive-compulsive disorder 11.2
16 migraine with or without aura 1 11.2
17 parkinson disease, late-onset 11.2
18 hypersomnia 11.2
19 corticosterone methyloxidase type i deficiency 11.2
20 dementia, lewy body 10.9
21 attention deficit-hyperactivity disorder 10.9
22 drug-induced hepatitis 10.9
23 gastroparesis 10.9
24 hepatitis d 10.9
25 codeine toxicity 10.9
26 acetaminophen metabolism 10.9
27 amelogenesis imperfecta, type ib 10.9
28 galactorrhea 10.9
29 amelogenesis imperfecta, type ie 10.9
30 drug metabolism, poor, cyp2d6-related 10.9
31 human immunodeficiency virus type 1 10.9
32 leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism 10.9
33 leukodystrophy, hypomyelinating, 13 10.9
34 female stress incontinence 10.9
35 autoimmune disease of gastrointestinal tract 10.9
36 central nervous system disease 10.9
37 substance dependence 10.9
38 pseudobulbar affect 10.9
39 toxic oil syndrome 10.9
40 disease of mental health 10.7
41 mental depression 10.7
42 resistance to tamoxifene 10.7
43 antidepressant or antipsychotic toxicity or dose selection 10.7
44 breast cancer 10.3
45 lung cancer 10.2
46 hepatitis 10.2
47 alzheimer disease 10.1
48 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.1
49 aging 10.0
50 hepatitis c 10.0

Graphical network of the top 20 diseases related to Cytochrome P450 2d6 Variant:



Diseases related to Cytochrome P450 2d6 Variant

Symptoms & Phenotypes for Cytochrome P450 2d6 Variant

Drugs & Therapeutics for Cytochrome P450 2d6 Variant

Search Clinical Trials , NIH Clinical Center for Cytochrome P450 2d6 Variant

Genetic Tests for Cytochrome P450 2d6 Variant

Anatomical Context for Cytochrome P450 2d6 Variant

MalaCards organs/tissues related to Cytochrome P450 2d6 Variant:

38
Liver

Publications for Cytochrome P450 2d6 Variant

Articles related to Cytochrome P450 2d6 Variant:

# Title Authors Year
1
Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. ( 9012401 )
1997

Variations for Cytochrome P450 2d6 Variant

Expression for Cytochrome P450 2d6 Variant

Search GEO for disease gene expression data for Cytochrome P450 2d6 Variant.

Pathways for Cytochrome P450 2d6 Variant

GO Terms for Cytochrome P450 2d6 Variant

Sources for Cytochrome P450 2d6 Variant

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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