MCID: CYT003
MIFTS: 11

Cytokine Receptor Deficiency malady

Summaries for Cytokine Receptor Deficiency

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64Wikipedia, 33MalaCards
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Wikipedia:64 Cytokine receptors are receptors that bind cytokines. more...

MalaCards: Cytokine Receptor Deficiency is related to encephalitis and hyperglycemia. An important gene associated with Cytokine Receptor Deficiency is IL18R1 (interleukin 18 receptor 1), and among its related pathways are Leishmaniasis and Development PDGF signaling via STATs and NF-kB. The compounds vesnarinone and endotoxin have been mentioned in the context of this disorder. Affiliated tissues include t cells.

Aliases & Classifications for Cytokine Receptor Deficiency

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43NIH Rare Diseases
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Aliases & Descriptions:

cytokine receptor deficiency 43


Related Diseases for Cytokine Receptor Deficiency

Sources:
17GeneCards, 18GeneDecks
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Graphical network of diseases related to Cytokine Receptor Deficiency:



Diseases related to cytokine receptor deficiency

Clinical Features for Cytokine Receptor Deficiency

Drugs & Therapeutics for Cytokine Receptor Deficiency

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Cytokine Receptor Deficiency

Drug clinical trials:

Search ClinicalTrials for Cytokine Receptor Deficiency

Search NIH Clinical Center for Cytokine Receptor Deficiency

Search CenterWatch for Cytokine Receptor Deficiency

Genetic Tests for Cytokine Receptor Deficiency

Anatomical Context for Cytokine Receptor Deficiency

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33MalaCards
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MalaCards organs/tissues related to Cytokine Receptor Deficiency:

33
T cells

Animal Models for Cytokine Receptor Deficiency or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Cytokine Receptor Deficiency

Sources:
51PubMed
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Articles related to Cytokine Receptor Deficiency:

idTitleAuthorsYear
1
KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors. (19592277)
2009
2
Severe cutaneous papillomavirus disease after haemopoietic stem-cell transplantation in patients with severe combined immune deficiency caused by common gammac cytokine receptor subunit or JAK-3 deficiency. (15207958)
2004
3
T-lymphocyte differentiation and proliferation in the absence of the cytoplasmic tail of the common cytokine receptor gamma c chain in a severe combined immune deficiency X1 patient. (8781427)
1996

Genetic Variations for Cytokine Receptor Deficiency

Expression for genes affiliated with Cytokine Receptor Deficiency

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cytokine Receptor Deficiency

Search GEO for disease gene expression data for Cytokine Receptor Deficiency.

Pathways for genes affiliated with Cytokine Receptor Deficiency

Sources:
30KEGG, 38NCBI BioSystems Database
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Pathways related to Cytokine Receptor Deficiency according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.1NOS2, IL18R1
2
Development PDGF signaling via STATs and NF-kB
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9.1NOS2, IL18R1

Compounds for genes affiliated with Cytokine Receptor Deficiency

Sources:
45Novoseek
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Compounds related to Cytokine Receptor Deficiency according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1vesnarinone459.2IL18R1, NOS2
2endotoxin459.1IL18R1, NOS2
3adenylate459.1NOS2, IL18R1
4ly294002459.0NOS2, IL18R1
5pge2458.8NOS2, IL18R1

GO Terms for genes affiliated with Cytokine Receptor Deficiency

Products for genes affiliated with Cytokine Receptor Deficiency

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cytokine Receptor Deficiency

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet