MCID: CYT005
MIFTS: 51

Cytomegalovirus Retinitis

Categories: Rare diseases, Eye diseases

Aliases & Classifications for Cytomegalovirus Retinitis

MalaCards integrated aliases for Cytomegalovirus Retinitis:

Name: Cytomegalovirus Retinitis 12 49 41 14 69
Cmv Retinitis 12 51

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology 12 DOID:0080160
MeSH 41 D017726
UMLS 69 C0206178

Summaries for Cytomegalovirus Retinitis

Disease Ontology : 12 A retinitis that has material basis in Cytomegalovirus.

MalaCards based summary : Cytomegalovirus Retinitis, also known as cmv retinitis, is related to anterior uveitis and uveitis. An important gene associated with Cytomegalovirus Retinitis is IL10RA (Interleukin 10 Receptor Subunit Alpha), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Cidofovir and Ganciclovir have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and t cells, and related phenotypes are cellular and hematopoietic system

Wikipedia : 72 Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that... more...

Related Diseases for Cytomegalovirus Retinitis

Diseases related to Cytomegalovirus Retinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 176)
# Related Disease Score Top Affiliating Genes
1 anterior uveitis 29.9 HLA-B TNF
2 uveitis 29.9 HLA-B IFNG TNF
3 hematopoietic stem cell transplantation 29.4 HLA-B IFNG TNF
4 cytomegalovirus infection 29.4 IFNG TNF
5 optic neuritis 29.3 CCR5 TNF
6 arthritis 28.7 CSF2 HLA-DQB1 IFNG TNF
7 systemic lupus erythematosus 28.5 CCR5 HLA-DQB1 IFNG TNF
8 aplastic anemia 28.4 CSF2 HLA-B IFNG TNF
9 acquired immunodeficiency syndrome 28.3 CCR2 CCR5 CSF2 HLA-B IFNG TNF
10 rheumatoid arthritis 27.5 CCR2 CSF2 HLA-B HLA-DQB1 IFNG TNF
11 human immunodeficiency virus type 1 27.2 CCR2 CCR5 CD9 HLA-B IFNG TNF
12 retinitis 11.0
13 giant cell myocarditis 10.4 HLA-B IL10RA
14 idiopathic inflammatory myopathy 10.3 HLA-B HLA-DQB1
15 pityriasis rosea 10.3 HLA-B HLA-DQB1
16 burns 10.3 CSF2 TNF
17 post-transplant lymphoproliferative disease 10.3 IL10RA TNF
18 retinal detachment 10.3
19 beryllium disease 10.3 HLA-DQB1 TNF
20 autoimmune pancreatitis 10.3 HLA-DQB1 TNF
21 idiopathic achalasia 10.2 HLA-DQB1 TNF
22 lichen sclerosus 10.2 HLA-DQB1 TNF
23 granulocytopenia 10.2 CSF2 TNF
24 microscopic polyangiitis 10.2 HLA-B TNF
25 sialadenitis 10.2 HLA-DQB1 TNF
26 nontuberculous mycobacterial lung disease 10.2 HLA-B TNF
27 alveolar echinococcosis 10.2 HLA-B TNF
28 endometritis 10.2 HLA-DQB1 TNF
29 mucocutaneous leishmaniasis 10.2 CCR5 TNF
30 severe hemophilia a 10.1 HLA-DQB1 TNF
31 ileitis 10.1 CSF2 TNF
32 aphthous stomatitis 10.1 HLA-B TNF
33 hydrops, lactic acidosis, and sideroblastic anemia 10.1
34 leukemia 10.1
35 lymphoma 10.1
36 macular retinal edema 10.1
37 candida glabrata 10.0 CSF2 IFNG
38 cyclic neutropenia 10.0 CSF2 IFNG
39 carotid artery thrombosis 10.0 CSF2 IFNG
40 human t-cell leukemia virus type 2 10.0 CSF2 IFNG
41 refractory celiac disease 10.0 HLA-DQB1 IFNG
42 cryptococcal meningitis 10.0 CSF2 IFNG
43 good syndrome 10.0
44 lymphoblastic leukemia 10.0
45 paraneoplastic pemphigus 10.0 HLA-B HLA-DQB1
46 complex regional pain syndrome 10.0 HLA-B TNF
47 peanut allergy 10.0 HLA-DQB1 IFNG
48 staphylococcal toxic shock syndrome 10.0 IFNG TNF
49 autoimmune myocarditis 10.0 IFNG TNF
50 histoplasmosis 10.0 HLA-B IFNG

Graphical network of the top 20 diseases related to Cytomegalovirus Retinitis:



Diseases related to Cytomegalovirus Retinitis

Symptoms & Phenotypes for Cytomegalovirus Retinitis

MGI Mouse Phenotypes related to Cytomegalovirus Retinitis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.98 TNF HLA-DQB1 CCR2 IFNG CCR5 IL10RA
2 hematopoietic system MP:0005397 9.97 HLA-DQB1 CCR2 IFNG CCR5 IL10RA CD9
3 cardiovascular system MP:0005385 9.93 TNF CSF2 HLA-DQB1 CCR2 IFNG CCR5
4 immune system MP:0005387 9.92 HLA-DQB1 CCR2 IFNG CCR5 IL10RA CD9
5 digestive/alimentary MP:0005381 9.88 HLA-DQB1 CCR2 IFNG CCR5 IL10RA TNF
6 liver/biliary system MP:0005370 9.65 TNF HLA-DQB1 CCR2 IFNG CCR5
7 neoplasm MP:0002006 9.55 CCR2 IFNG CCR5 CSF2 TNF
8 reproductive system MP:0005389 9.43 HLA-DQB1 IFNG CCR5 CD9 CSF2 TNF
9 respiratory system MP:0005388 9.1 HLA-DQB1 CCR2 IFNG CD9 TNF CSF2

Drugs & Therapeutics for Cytomegalovirus Retinitis

Drugs for Cytomegalovirus Retinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 111)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cidofovir Approved Phase 4,Phase 3,Phase 2,Phase 1 113852-37-2 60613
2
Ganciclovir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 82410-32-0 3454
3
Foscarnet Approved Phase 4,Phase 3,Phase 2,Phase 1 4428-95-9, 63585-09-1 3415
4
Probenecid Approved, Investigational Phase 4,Phase 2,Phase 1 57-66-9 4911
5
Phosphonoacetic Acid Experimental Phase 4,Phase 3,Phase 2,Phase 1 4408-78-0 546
6 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
7 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1
8 Ganciclovir triphosphate Phase 4,Phase 3,Phase 2,Phase 1
9 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
10 Anti-Retroviral Agents Phase 4,Phase 3,Phase 2,Phase 1
11 Reverse Transcriptase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
12 Antirheumatic Agents Phase 4,Phase 2,Phase 1
13 Renal Agents Phase 4,Phase 2,Phase 1
14
Valganciclovir Approved, Investigational Phase 3 175865-60-8 64147
15 Antibodies Phase 2, Phase 3,Phase 1
16 Antibodies, Monoclonal Phase 2, Phase 3,Phase 1
17 Immunoglobulins Phase 2, Phase 3,Phase 1
18 Acyclovir Phase 3
19
Nelfinavir Approved Phase 2 159989-64-7 64143
20 Fomivirsen Phase 2
21 Anti-HIV Agents Phase 2,Phase 1
22 HIV Protease Inhibitors Phase 2
23
protease inhibitors Phase 2
24
Aldesleukin Approved Phase 1 110942-02-4, 85898-30-2
25 Analgesics Phase 1
26 Analgesics, Non-Narcotic Phase 1
27 Interleukin-2 Phase 1
28 Peripheral Nervous System Agents Phase 1
29
Zidovudine Approved 30516-87-1 35370
30
Interferon beta-1b Approved 145155-23-3
31
Alfentanil Approved, Illicit 71195-58-9 51263
32
Aripiprazole Approved, Investigational 129722-12-9 60795
33
Ceftazidime Approved 72558-82-8, 78439-06-2 5481173
34
Ciprofloxacin Approved, Investigational 85721-33-1 2764
35
Clozapine Approved 5786-21-0 2818
36
Dexamethasone Approved, Investigational, Vet_approved 50-02-2 5743
37
Diazepam Approved, Illicit, Investigational, Vet_approved 439-14-5 3016
38
Epinephrine Approved, Vet_approved 51-43-4 5816
39
Fosphenytoin Approved, Investigational 93390-81-9 56339
40
Haloperidol Approved 52-86-8 3559
41
Heparin Approved, Investigational 9005-49-6 46507594 772
42
Hydromorphone Approved, Illicit 466-99-9 5284570
43
Meropenem Approved, Investigational 119478-56-7 441130 64778
44
Methylprednisolone Approved, Vet_approved 83-43-2 6741
45
Midazolam Approved, Illicit 59467-70-8 4192
46
Molindone Approved 7416-34-4 23897
47
Morphine Approved, Investigational 57-27-2 5288826
48
Nicardipine Approved, Investigational 55985-32-5 4474
49
Olanzapine Approved, Investigational 132539-06-1 4585
50
Oseltamivir Approved 196618-13-0, 204255-11-8 65028

Interventional clinical trials:

(show top 50) (show all 66)

# Name Status NCT ID Phase Drugs
1 Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis Completed NCT00000894 Phase 4 Cidofovir;Probenecid;Ganciclovir
2 A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium) Completed NCT00002125 Phase 4 Foscarnet sodium
3 Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration Completed NCT01866397 Phase 4
4 Use of Cidofovir for Recurrent Respiratory Papillomatosis Completed NCT00205374 Phase 4 Cidofovir;Placebo
5 Valganciclovir in Patients With CMV Retinitis and AIDS Who Cannot Take Drugs by Injection Unknown status NCT00017784 Phase 3 Valganciclovir
6 A Randomized, Controlled Study of Intravenous Ganciclovir Therapy for Peripheral Cytomegalovirus Retinitis in Patients With AIDS Completed NCT00000688 Phase 3 Ganciclovir
7 Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT) Completed NCT00000134 Phase 3 Ganciclovir;Foscarnet
8 Studies of the Ocular Complications of AIDS (SOCA)--Monoclonal Antibody CMV Retinitis Trial (MACRT) Completed NCT00000135 Phase 2, Phase 3 MSL-109
9 A Treatment Protocol for the Use of Intravenous Ganciclovir in AIDS Patients With Immediately Sight-Threatening CMV Retinitis Completed NCT00000698 Phase 3 Ganciclovir
10 Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT) Completed NCT00000143 Phase 3 Cidofovir intravenous
11 Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT) Completed NCT00000136 Phase 3 Foscarnet;Ganciclovir
12 Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis Completed NCT00002070 Phase 3 Sargramostim;Ganciclovir
13 Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT) Completed NCT00000142 Phase 2, Phase 3 Cidofovir
14 Ganciclovir Implant Study for Cytomegalovirus Retinitis Completed NCT00000118 Phase 3
15 A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes Completed NCT00002377 Phase 3 Valganciclovir;Ganciclovir
16 Valganciclovir in Prevention of Cytomegalovirus (CMV) Reactivation Following Allogeneic-Stem Cell Transplantation (SCT) Completed NCT00330018 Phase 3 Valganciclovir;Acyclovir
17 A Randomized Comparison of Intravitreal ISIS 2922 Plus Ganciclovir Versus Ganciclovir as Treatment for Patients With Cytomegalovirus Retinitis ( CMVR ) Completed NCT00002156 Phase 2 Fomivirsen sodium;Ganciclovir
18 Phase II Randomized Study of Cidofovir for Peripheral Cytomegalovirus Retinitis Completed NCT00004794 Phase 2 cidofovir
19 A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure Completed NCT00000691 Phase 2 Foscarnet sodium
20 CMV Retinitis Retreatment Trial Completed NCT00000766 Phase 2 Foscarnet sodium;Ganciclovir
21 The Safety and Effectiveness of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Completed NCT00002437 Phase 2 Cidofovir;Probenecid
22 The Safety and Effectiveness of ISIS 2922 in Patients With AIDS Who Have Cytomegalovirus (CMV) of the Eyes Completed NCT00002356 Phase 2 Fomivirsen sodium
23 A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis Completed NCT00002169 Phase 2 Nelfinavir mesylate
24 A Phase II/III Trial of Human Anti-CMV Monoclonal Antibody MSL 109 (MACRT) Completed NCT00000836 Phase 2 Sevirumab
25 Comparison of Two Methods in the Treatment of Cytomegalovirus of the Eyes in Patients With AIDS Completed NCT00001061 Phase 2 Sevirumab;Foscarnet sodium;Ganciclovir
26 The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIV Completed NCT00001034 Phase 2 Ganciclovir
27 A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Cannot Use Ganciclovir Withdrawn NCT00000697 Phase 2 Foscarnet sodium
28 A Phase I/II Open-Labelled Trial of Intravitreal Ganciclovir Salvage Therapy for AIDS Patients With Active CMV Retinitis Who Are Intolerant of Systemic Therapy Completed NCT00000673 Phase 1 Ganciclovir
29 A Phase I/II Trial to Assess the Safety and Tolerance of Escalating Doses of a Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Retinitis Completed NCT00002016 Phase 1 Sevirumab
30 Foscarnet Treatment of Serious CMV Retinitis Infection in Patients With Acquired Immunodeficiency Syndrome Completed NCT00000726 Phase 1 Foscarnet sodium
31 A Study of Ganciclovir in the Treatment of Cytomegalovirus of the Eyes Completed NCT00001062 Phase 1 Ganciclovir
32 A Study of Foscarnet Plus Ganciclovir in the Treatment of Cytomegalovirus of the Eye in Patients With AIDS Who Have Already Been Treated With Ganciclovir Completed NCT00000970 Phase 1 Foscarnet sodium;Ganciclovir
33 A Phase I Study of the Safety of Proleukin (Aldesleukin) in Combination With Ganciclovir and Antiretroviral Therapy in HIV Seropositive Patients With Cytomegalovirus (CMV) Retinitis Completed NCT00002321 Phase 1 Aldesleukin
34 A Phase I Pharmacokinetic and Tolerance Study of 28-Day Regimens of Oral Ganciclovir Completed NCT00000668 Phase 1 Ganciclovir
35 A Pharmacokinetic and Tolerance Study of Oral Ganciclovir in HIV-Infected Children With Asymptomatic Cytomegalovirus Infection and Low CD4 Cell Counts or Quiescent Cytomegalovirus Disease Completed NCT00000805 Phase 1 Ganciclovir
36 A Study of Cidofovir in HIV-Infected Children With Cytomegalovirus (CMV) Disease Withdrawn NCT00000881 Phase 1 Cidofovir;Probenecid
37 A Study of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Unknown status NCT00002384 Cidofovir
38 A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir Unknown status NCT00002301 Foscarnet sodium
39 Suppression of Cytomegalovirus Retinitis Utilizing High Dose Intravenous Acyclovir and Oral Zidovudine in Patients With AIDS Completed NCT00000693 Zidovudine;Acyclovir
40 A Randomized Controlled Study of the Efficacy and Safety of Maintenance Treatment With Oral Ganciclovir for Newly Diagnosed Cytomegalovirus Retinitis in People With AIDS Completed NCT00002257 Ganciclovir
41 A Randomized, Controlled Study of the Safety and Preventive Efficacy of Oral Ganciclovir When Used in Conjunction With An Intravitreal Ganciclovir Implant in the Treatment of Cytomegalovirus Retinitis Completed NCT00002134 Ganciclovir
42 A Study of the Safety and Tolerance of Long-Term Therapy With Intravenous Cytovene (Ganciclovir Sodium) for Cytomegalovirus Retinitis in Persons With AIDS Completed NCT00002034 Zidovudine;Ganciclovir
43 A Randomized Study Comparing the Safety and Efficacy of Two Regimens of Oral Ganciclovir to Intravenous Ganciclovir Maintenance Therapy for Cytomegalovirus Retinitis in People With AIDS Who Have Received Prior Ganciclovir Therapy Completed NCT00002247 Ganciclovir
44 A Study of ISIS 2922 in the Treatment of Advanced Cytomegalovirus Retinitis Completed NCT00002187 Fomivirsen sodium
45 An Open-Label Study of the Safety and Efficacy of Cidofovir for the Treatment of Relapsing Cytomegalovirus Retinitis in Patients With AIDS Completed NCT00002142 Cidofovir;Probenecid
46 Efficacy of Elevated CD4 Counts on CMV Retinitis Completed NCT00091884
47 Studies of the Ocular Complications of AIDS (SOCA) CMV Retinitis Trial: Foscarnet-Ganciclovir Component Completed NCT00000665 Foscarnet sodium;Ganciclovir
48 A Study of Valganciclovir in the Treatment of Cytomegalovirus (CMV) Retinitis in Patients With AIDS Completed NCT00002222 Valganciclovir
49 HPMPC (Cidofovir) Peripheral CMV Retinitis Trial Protocol Completed NCT00000799 Cidofovir;Probenecid
50 An Open-Label Safety Study of Oral Ganciclovir Maintenance Treatment of CMV Retinitis in People With Limited Venous Access Completed NCT00002135 Ganciclovir

Search NIH Clinical Center for Cytomegalovirus Retinitis

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: cytomegalovirus retinitis

Genetic Tests for Cytomegalovirus Retinitis

Anatomical Context for Cytomegalovirus Retinitis

MalaCards organs/tissues related to Cytomegalovirus Retinitis:

38
Eye, Retina, T Cells, Bone, Bone Marrow, Testes, Endothelial

Publications for Cytomegalovirus Retinitis

Articles related to Cytomegalovirus Retinitis:

(show top 50) (show all 586)
# Title Authors Year
1
Spectral domain optical coherence tomography and fundus autofluorescence findings in cytomegalovirus retinitis in HIV-infected patients. ( 29445945 )
2018
2
Synthesis, physicochemical properties and ocular pharmacokinetics of thermosensitive in situ hydrogels for ganciclovir in cytomegalovirus retinitis treatment. ( 29228826 )
2018
3
Cytomegalovirus Retinitis in Patients With Acquired Immunodeficiency Syndrome After Initiating Antiretroviral Therapy. ( 27984023 )
2017
4
Treatment of unilateral zone I cytomegalovirus retinitis in acute lymphoblastic leukemia with oral valganciclovir and intravitreal ganciclovir. ( 29118508 )
2017
5
OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN CYTOMEGALOVIRUS RETINITIS: A Longitudinal Study. ( 28145973 )
2017
6
Cytomegalovirus retinitis followed by immune recovery uveitis in an elderly patient with rheumatoid arthritis undergoing administration of methotrexate and tofacitinib combination therapy. ( 28389165 )
2017
7
Cytomegalovirus retinitis in Cape Town, South Africa: Clinical management and outcomes. ( 28604324 )
2017
8
Cytomegalovirus retinitis and HIV: Case reviews from KwaZulu-Natal Province, South Africa. ( 29022526 )
2017
9
Bilateral cytomegalovirus retinitis in a healthy infant. ( 28367531 )
2017
10
Cytomegalovirus Retinitis in Immunocompetent Young Male. ( 28969754 )
2017
11
Cytomegalovirus retinitis in a patient with secondary acute lymphosarcoma leukemia undergoing allogeneic hematopoietic stem-cell transplantation: A rare case report: a care-compliant article. ( 28489788 )
2017
12
Cytomegalovirus Retinitis: A Review. ( 28355091 )
2017
13
Reduced frequency of murine cytomegalovirus retinitis in C57BL/6 mice correlates with low levels of suppressor of cytokine signaling (SOCS)1 and SOCS3 expression within the eye during corticosteroid-induced immunosuppression. ( 28558309 )
2017
14
CYTOMEGALOVIRUS RETINITIS ASSOCIATED WITH OCCLUSIVE VASCULOPATHY IN AN ELDERLY, HUMAN IMMUNODEFICIENCY VIRUS-NEGATIVE MAN. ( 28937523 )
2017
15
Bilateral retinal detachment associated with cytomegalovirus retinitis. ( 29054478 )
2017
16
Cytomegalovirus Retinitis as a Presenting Feature of Multisystem Disorder: Dyskeratosis Congenita. ( 29422759 )
2017
17
COMPARISON OF VISUAL PROGNOSIS AND CLINICAL FEATURES OF CYTOMEGALOVIRUS RETINITIS IN HIV AND NON-HIV PATIENTS. ( 28118285 )
2017
18
Comparative analysis of cytomegalovirus retinitis and microvascular retinopathy in patients with acquired immunodeficiency syndrome. ( 28944199 )
2017
19
Cytokine Profiles in Aqueous Humor and Plasma of HIV-infected Individuals with Ocular Syphilis or Cytomegalovirus Retinitis. ( 28081374 )
2017
20
SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN MACULA-INVOLVING CYTOMEGALOVIRUS RETINITIS. ( 28376042 )
2017
21
Cytomegalovirus retinitis in relapsed or refractory low-grade B cell lymphoma patients treated with bendamustine. ( 28447162 )
2017
22
Cytomegalovirus retinitis in HIV-negative patients - associated conditions, clinical presentation, diagnostic methods and treatment strategy. ( 29068151 )
2017
23
Incidence Rates and Risk Factors for Vision Loss among AIDS-Related Cytomegalovirus Retinitis Patients in Southern Thailand. ( 28323489 )
2017
24
Management of Cytomegalovirus Retinitis in HIV and Non-HIV Patients. ( 26878441 )
2016
25
Good syndrome and other causes of cytomegalovirus retinitis in HIV-negative patients-case report and comprehensive review of the literature. ( 26809342 )
2016
26
Dual Intravitreal Injections With Foscarnet and Ganciclovir for Ganciclovir-Resistant Recurrent Cytomegalovirus Retinitis in a Congenitally Infected Infant. ( 27783090 )
2016
27
Sensitivity of the Cytomegalovirus Antigenemia Assay to Diagnose Cytomegalovirus Retinitis. ( 27883376 )
2016
28
Immune recovery uveitis in HIV patients with cytomegalovirus retinitis in the era of HAART therapy-a 5-year study from Singapore. ( 27822743 )
2016
29
Long-term Follow-up of Cytomegalovirus Retinitis in Non-HIV Immunocompromised Patients: Clinical Features and Visual Prognosis. ( 27005706 )
2016
30
Atypical Retinitis in the Setting of Prior Cytomegalovirus Retinitis. ( 27100908 )
2016
31
Treatment outcomes of reduced-dose intravitreal ganciclovir for cytomegalovirus retinitis. ( 27090644 )
2016
32
In Response to: Jeon and Lee's 'Cytomegalovirus Retinitis in a Human Immunodeficiency Virus-negative Cohort: Long-term Management and Complications'. ( 26943724 )
2016
33
Cytomegalovirus retinitis in pediatric stem cell transplants: report of a recent cluster and the development of a screening protocol. ( 27746296 )
2016
34
Frosted branch angiitis in acquired immunodeficiency syndrome patients with cytomegalovirus retinitis. ( 27640360 )
2016
35
Leukaemic infiltration and cytomegalovirus retinitis in a patient with acute T-cell lymphoblastic leukaemia in complete remission. ( 27402450 )
2016
36
Cytomegalovirus retinitis in an immunocompetent patient: A case report. ( 27331155 )
2016
37
Frosted Branch Angiitis Associated with Cytomegalovirus Retinitis. ( 26902566 )
2016
38
Cytomegalovirus Retinitis as the First Manifestation of Good Syndrome. ( 27715373 )
2016
39
Diagnostic Utility of Ocular Symptoms and Vision for Cytomegalovirus Retinitis. ( 27788232 )
2016
40
Cytomegalovirus retinitis. ( 26684874 )
2016
41
Bilateral Cytomegalovirus Retinitis in a Patient with Systemic Lupus Erythematosus. ( 27462259 )
2016
42
Cytomegalovirus Retinitis in a Patient Who Received Ruxolitinib. ( 26789901 )
2016
43
Retrospective study of cytomegalovirus retinitis complicated with acquired immunodeficiency syndrome. ( 26309620 )
2015
44
Cytomegalovirus Retinitis in a Human Immunodeficiency Virus-negative Cohort: Long-term Management and Complications. ( 25760914 )
2015
45
Clinical Outcomes of Retinal Detachment Surgery following Cytomegalovirus Retinitis in Patients on Highly Active Anti-retroviral Therapy for Acquired Immune Deficiency Syndrome. ( 26221740 )
2015
46
Effective treatment of cytomegalovirus retinitis and neuritis with retrobulbar ganciclovir after treosulfan-based autologous bone marrow transplant. ( 26638547 )
2015
47
Unilateral Ischemic Maculopathy Associated with Cytomegalovirus Retinitis in Patients with AIDS: Optical Coherence Tomography Findings. ( 27051496 )
2015
48
Retinal detachment associated with AIDS-related cytomegalovirus retinitis: risk factors in a resource-limited setting. ( 25448999 )
2015
49
Retinal structural features of cytomegalovirus retinitis with acquired immunodeficiency syndrome: an adaptive optics imaging and optical coherence tomography study. ( 26148637 )
2015
50
Treatment of cytomegalovirus retinitis with cytomegalovirus-specific T-lymphocyte infusion. ( 25559515 )
2015

Variations for Cytomegalovirus Retinitis

Expression for Cytomegalovirus Retinitis

Search GEO for disease gene expression data for Cytomegalovirus Retinitis.

Pathways for Cytomegalovirus Retinitis

Pathways related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

(show all 37)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.78 CCR2 CCR5 CSF2 HLA-B HLA-DQB1 IFNG
2
Show member pathways
13.45 CCR2 CCR5 CSF2 IFNG IL10RA TNF
3
Show member pathways
13.2 CCR2 CCR5 CSF2 IL10RA TNF
4
Show member pathways
13.1 CCR2 CCR5 CSF2 IL10RA TNF
5
Show member pathways
12.68 HLA-B HLA-DQB1 IFNG TNF
6
Show member pathways
12.67 CCR2 CCR5 CSF2 HLA-B HLA-DQB1 IFNG
7
Show member pathways
12.62 HLA-B HLA-DQB1 IFNG TNF
8
Show member pathways
12.46 HLA-DQB1 IFNG IL10RA TNF
9
Show member pathways
12.41 CCR5 CSF2 HLA-B TNF
10
Show member pathways
12.36 CSF2 HLA-B IFNG TNF
11
Show member pathways
12.26 CCR5 CSF2 IFNG TNF
12 12.24 CSF2 HLA-B HLA-DQB1 TNF
13
Show member pathways
12.2 CSF2 IFNG IL10RA
14
Show member pathways
12.16 CSF2 IFNG TNF
15 12.09 HLA-B HLA-DQB1 IFNG IL10RA
16
Show member pathways
12.01 HLA-B IFNG TNF
17 12.01 HLA-DQB1 IFNG IL10RA TNF
18 11.87 CCR2 IFNG TNF
19 11.85 CSF2 IFNG TNF
20
Show member pathways
11.83 CCR5 HLA-DQB1 IFNG IL10RA TNF
21 11.76 CSF2 IFNG TNF
22
Show member pathways
11.62 CSF2 IFNG TNF
23 11.61 CD9 CSF2 HLA-DQB1 TNF
24 11.6 CSF2 IFNG TNF
25 11.58 CCR2 CCR5 IFNG IL10RA
26 11.51 CSF2 HLA-DQB1 IFNG TNF
27 11.5 CCR2 CSF2 TNF
28
Show member pathways
11.49 CSF2 IFNG TNF
29 11.35 CCR2 IFNG TNF
30 11.33 IFNG TNF
31 11.24 HLA-B IFNG
32 11.21 IFNG TNF
33 11.21 IL10RA TNF
34
Show member pathways
11.17 CSF2 IFNG TNF
35 11.16 IFNG TNF
36 11.06 CSF2 IFNG TNF
37 10.71 CCR2 CCR5 CSF2 IL10RA TNF

GO Terms for Cytomegalovirus Retinitis

Cellular components related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.65 CCR2 CCR5 CD9 HLA-B TNF
2 clathrin-coated endocytic vesicle membrane GO:0030669 9.32 CD9 HLA-DQB1
3 cell surface GO:0009986 9.26 CCR5 CD9 HLA-B TNF
4 integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 9.16 HLA-B HLA-DQB1
5 external side of plasma membrane GO:0009897 8.92 CCR2 CCR5 CD9 TNF

Biological processes related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.74 CCR5 CSF2 TNF
2 cell surface receptor signaling pathway GO:0007166 9.73 CCR5 CD9 IFNG
3 cellular response to lipopolysaccharide GO:0071222 9.61 CCR5 CSF2 TNF
4 positive regulation of interferon-gamma production GO:0032729 9.59 CCR2 TNF
5 positive regulation of nitric oxide biosynthetic process GO:0045429 9.58 IFNG TNF
6 antigen processing and presentation GO:0019882 9.58 HLA-B HLA-DQB1
7 extrinsic apoptotic signaling pathway GO:0097191 9.55 IFNG TNF
8 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.54 CSF2 TNF
9 interferon-gamma-mediated signaling pathway GO:0060333 9.54 HLA-B HLA-DQB1 IFNG
10 protein import into nucleus, translocation GO:0000060 9.52 IFNG TNF
11 positive regulation of protein complex assembly GO:0031334 9.51 IFNG TNF
12 positive regulation of osteoclast differentiation GO:0045672 9.49 IFNG TNF
13 dendritic cell chemotaxis GO:0002407 9.48 CCR2 CCR5
14 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.46 IFNG TNF
15 humoral immune response GO:0006959 9.43 CCR2 IFNG TNF
16 positive regulation of podosome assembly GO:0071803 9.4 CSF2 TNF
17 positive regulation of interleukin-23 production GO:0032747 9.32 CSF2 IFNG
18 immune response GO:0006955 9.17 CCR2 CCR5 CSF2 HLA-B HLA-DQB1 IFNG
19 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.16 IFNG TNF
20 positive regulation of vitamin D biosynthetic process GO:0060557 8.96 IFNG TNF

Molecular functions related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.43 CSF2 IFNG TNF
2 peptide antigen binding GO:0042605 9.16 HLA-B HLA-DQB1
3 chemokine receptor activity GO:0004950 8.96 CCR2 CCR5
4 C-C chemokine receptor activity GO:0016493 8.62 CCR2 CCR5

Sources for Cytomegalovirus Retinitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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