MCID: CYT005
MIFTS: 57

Cytomegalovirus Retinitis malady

Rare diseases category
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Summaries for Cytomegalovirus Retinitis

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Wikipedia:65 Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that... more...

MalaCards based summary: Cytomegalovirus Retinitis is related to intraocular lymphoma and acquired immunodeficiency syndrome. An important gene associated with Cytomegalovirus Retinitis is IL10RA (interleukin 10 receptor, alpha), and among its related pathways are Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions and Staphylococcus aureus infection. The drugs ganciclovir and ganciclovir sodium and the compounds mdms and mip 1alpha have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and t cells, and related mouse phenotypes are renal/urinary system and vision/eye.

Aliases & Classifications for Cytomegalovirus Retinitis

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Cytomegalovirus Retinitis, Aliases & Descriptions:

Name: Cytomegalovirus Retinitis 42 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Related Diseases for Cytomegalovirus Retinitis

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Diseases related to Cytomegalovirus Retinitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 167)
idRelated DiseaseScoreTop Affiliating Genes
1intraocular lymphoma30.8IL10
2acquired immunodeficiency syndrome30.7CSF2, IL2, CCR5, CCR2, CXCL12, HLA-B
3acute lymphoblastic leukemia30.6HLA-B, CXCL12, CSF2, CD9
4encephalitis30.4CD9, CCR5, HLA-B
5leprosy30.4HLA-DRB1, IL2
6tuberculoid leprosy30.1IFNG, IL10
7common variable immunodeficiency30.1IL10, IL2
8hodgkin's lymphoma30.1HLA-B, HLA-A, IL2, CSF2
9aplastic anemia30.1FASLG, IFNG, CSF2
10uveitis30.1IL10, IFNG, CCR5, TNF, HLA-A, HLA-B
11pneumonia30.0CD9, CSF2, IL10, TNF
12diabetes mellitus29.7HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, TNF
13myeloma29.6HLA-B, FASLG, CXCL12, IL2, CSF2, CD9
14leukemia28.8HLA-B, HLA-A, CD9, CSF2, IL2, IFNG
15arthritis28.7HLA-B, HLA-A, HLA-DRB1, TNF, CCR5, IFNG
16systemic lupus erythematosus28.7IL10RA, IL10, IL2, IFNG, CCR5, FASLG
17tuberculosis28.3CD9, IL10, IL2, IFNG, CXCL12, TNF
18rheumatoid arthritis27.8CXCL12, FASLG, TNF, HLA-DRB1, HLA-DQB1, HLA-A
19retinitis11.4
20retinal detachment10.6
21periapical granuloma10.6CCR5
22toxic epidermal necrolysis10.5FASLG
23felty's syndrome10.5CSF2
24cystoid macular edema10.5
25aphthous stomatitis10.4HLA-B
26thyroiditis10.4HLA-DRB1, FASLG
27blau syndrome10.4TNF
28hematopoietic stem cell transplantation10.4
29stomatitis10.4CSF2
30vogt-koyanagi-harada disease10.3HLA-DRB1, FASLG
31multiple sclerosis 110.3HLA-DQB1, HLA-DRB1
32retinal vein occlusion10.3
33central retinal vein occlusion10.3
34good syndrome10.3
35lupus erythematosus10.3
36lymphoblastic leukemia10.3
37human immunodeficiency virus infectious disease10.3HLA-A, FASLG
38autoimmune lymphoproliferative syndrome10.3FASLG, IL10
39hiv/aids10.3
40wegener's granulomatosis10.3
41choroiditis10.3
42anterior uveitis10.3
43congenital cytomegalovirus10.3
44capillary leak syndrome10.2IL2, CSF2
45choriocarcinoma10.2CD9, CSF2, FASLG
46bruton-type agammaglobulinemia10.2CXCL12, IL2
47dementia10.2CD9, CCR5, CXCL12
48familial mediterranean fever10.2HLA-A, TNF
49stevens-johnson syndrome10.2FASLG, HLA-A, HLA-B
50hepatitis10.2FASLG, HLA-DRB1, HLA-A

Graphical network of the top 20 diseases related to Cytomegalovirus Retinitis:



Diseases related to cytomegalovirus retinitis

Symptoms for Cytomegalovirus Retinitis

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Drugs & Therapeutics for Cytomegalovirus Retinitis

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Drug clinical trials:

Search ClinicalTrials for Cytomegalovirus Retinitis

Search NIH Clinical Center for Cytomegalovirus Retinitis

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Cytomegalovirus Retinitis

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Anatomical Context for Cytomegalovirus Retinitis

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MalaCards organs/tissues related to Cytomegalovirus Retinitis:

32
Eye, Retina, T cells, Bone, Bone marrow, Testes, Liver, Endothelial, Heart, Lung, Nk cells

Animal Models for Cytomegalovirus Retinitis or affiliated genes

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MGI Mouse Phenotypes related to Cytomegalovirus Retinitis:

36 (show all 20)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.8CSF2, IFNG, CCR2, FASLG, HLA-DQB1
2MP:00053917.8TNF, FASLG, CCR2, CCR5, IFNG, IL10
3MP:00053697.6HLA-DQB1, TNF, CXCL12, CCR5, IFNG, IL10
4MP:00053907.3TNF, FASLG, CCR2, IFNG, IL10, CSF2
5MP:00053797.3HLA-DQB1, TNF, FASLG, IFNG, IL2, IL10
6MP:00020067.3TNF, FASLG, CCR2, CCR5, IFNG, IL2
7MP:00030127.1HLA-B, TNF, CXCL12, CCR2, CCR5, IFNG
8MP:00053817.0HLA-DQB1, TNF, FASLG, CCR2, CCR5, IFNG
9MP:00053707.0HLA-DQB1, TNF, FASLG, CXCL12, CCR2, CCR5
10MP:00036316.9HLA-B, HLA-DQB1, TNF, FASLG, CXCL12, CCR2
11MP:00053886.7HLA-DQB1, TNF, FASLG, CCR2, IFNG, IL2
12MP:00053866.7HLA-B, HLA-DQB1, TNF, CCR2, CCR5, IFNG
13MP:00053766.7CCR2, FASLG, TNF, HLA-DQB1, CCR5, IFNG
14MP:00053856.6HLA-DQB1, TNF, FASLG, CXCL12, CCR2, CCR5
15MP:00053846.4CXCL12, FASLG, TNF, HLA-DQB1, CCR2, CCR5
16MP:00053896.4HLA-DQB1, TNF, FASLG, CXCL12, CCR5, IFNG
17MP:00053786.4HLA-DQB1, TNF, CCR2, IFNG, IL2, IL10
18MP:00107686.2HLA-B, HLA-DQB1, TNF, FASLG, CXCL12, CCR2
19MP:00053975.6CD9, HLA-B, HLA-DQB1, TNF, FASLG, CXCL12
20MP:00053875.5CXCL12, FASLG, TNF, HLA-DQB1, HLA-B, CCR2

Publications for Cytomegalovirus Retinitis

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Articles related to Cytomegalovirus Retinitis:

(show top 50)    (show all 517)
idTitleAuthorsYear
1
Telemedicine diagnosis of cytomegalovirus retinitis by nonophthalmologists. (24945306)
2014
2
Herpetic (non-cytomegalovirus) retinal infections in patients with the acquired immunodeficiency syndrome. (23544389)
2013
3
A messenger at the door: cytomegalovirus retinitis in myeloma patients with progressive disease. (23790037)
2013
4
Telemedicine screening for cytomegalovirus retinitis using digital fundus photography. (23756239)
2013
5
Retinal metastasis simulating cytomegalovirus retinitis. (22938704)
2012
6
Risk factors for cytomegalovirus retinitis in patients with cytomegalovirus viremia after hematopoietic stem cell transplantation. (22657564)
2012
7
Evidence for multiple cell death pathways during development of experimental cytomegalovirus retinitis in mice with retrovirus-induced immunosuppression: apoptosis, necroptosis, and pyroptosis. (22837196)
2012
8
The epidemiology and incidence of cytomegalovirus retinitis in the HIV population in Singapore over 6 years. (23074211)
2012
9
Association of host genetic risk factors with the course of cytomegalovirus retinitis in patients infected with human immunodeficiency virus. (21396623)
2011
10
Cytomegalovirus retinitis in an immunocompromised infant: a case report and review of the literature. (21941498)
2011
11
Evaluation of the United States public health service guidelines for discontinuation of anticytomegalovirus therapy after immune recovery in patients with cytomegalovirus retinitis. (21742304)
2011
12
Mortality associated with resistant cytomegalovirus among patients with cytomegalovirus retinitis and AIDS. (19818505)
2010
13
Intravitreal ganciclovir in the management of non-AIDS-related human cytomegalovirus retinitis. (20379302)
2010
14
Good's syndrome in a patient with cytomegalovirus retinitis. (18382022)
2008
15
Increased incidence of cytomegalovirus retinitis after allogeneic hematopoietic stem cell transplantation. (17220797)
2007
16
Cytomegalovirus retinitis following intravitreal injection of triamcinolone: report of two cases. (17403022)
2007
17
Cytomegalovirus retinitis: the neglected disease of the AIDS pandemic. (18052600)
2007
18
Long-term follow-up of a cohort of HIV-infected patients who discontinued maintenance therapy for cytomegalovirus retinitis. (16632459)
2006
19
Indocyanine green angiographic findings in a cytomegalovirus retinitis patient. (16334614)
2005
20
A case of immune recovery vitritis induced by donor leukocyte infusion for the treatment of cytomegalovirus retinitis. (16146543)
2005
21
PCR with the aqueous humor, blood leukocytes and vitreous of patients affected by cytomegalovirus retinitis and immune recovery uveitis. (14688435)
2004
22
Human cytomegalovirus retinitis: pathogenicity, immune evasion and persistence. (12706995)
2003
23
Interleukin-2 immunotherapy of murine cytomegalovirus retinitis during MAIDS correlates with increased intraocular CD8+ T-cell infiltration. (12711843)
2003
24
Mortality risk for patients with cytomegalovirus retinitis and acquired immune deficiency syndrome. (14583871)
2003
25
Visual loss in patients with cytomegalovirus retinitis and acquired immunodeficiency syndrome before widespread availability of highly active antiretroviral therapy. (12523893)
2003
26
Murine cytomegalovirus retinitis during retrovirus-induced immunodeficiency (MAIDS) in mice: interleukin-2 immunotherapy correlates with increased intraocular levels of perforin mRNA. (12895694)
2003
27
Incidence and management of cataract after retinal detachment repair with silicone oil in immune compromised patients with cytomegalovirus retinitis. (14644210)
2003
28
Safety of intravitreous fomivirsen for treatment of cytomegalovirus retinitis in patients with AIDS. (11931782)
2002
29
HIV and cytomegalovirus viral load and clinical outcomes in AIDS and cytomegalovirus retinitis patients: Monoclonal Antibody Cytomegalovirus Retinitis Trial. (11919489)
2002
30
Protease inhibitor therapy is associated with markedly prolonged time to relapse and improved survival in AIDS patients with cytomegalovirus retinitis. (11564333)
2001
31
Cystoid macular edema in patients with acquired immune deficiency syndrome and cytomegalovirus retinitis. (11071031)
2000
32
Highly active antiretroviral therapy-related immune recovery in AIDS patients with cytomegalovirus retinitis. (10811078)
2000
33
HIV associated cytomegalovirus retinitis in Melbourne, Australia. (10961210)
2000
34
Visual and anatomic outcomes associated with posterior segment complications after ganciclovir implant procedures in patients with AIDS and cytomegalovirus retinitis. (10088738)
1999
35
Cystoid macular edema following immune recovery and treatment with cidofovir for cytomegalovirus retinitis. (10541898)
1999
36
Successive intraocular nocardiosis and cytomegalovirus retinitis after cardiac transplantation. (9682720)
1998
37
Optic nerve head neovascularization in a patient with inactive cytomegalovirus retinitis and immune recovery. (9727534)
1998
38
Iritis and hypotony after treatment with intravenous cidofovir for cytomegalovirus retinitis. (9194724)
1997
39
New therapies for cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. (9109331)
1997
40
Successful use of cidofovir in treating AIDS-related cytomegalovirus retinitis, encephalitis, and esophagitis. (9215660)
1997
41
Antibody alone does not prevent experimental cytomegalovirus retinitis in mice with retrovirus-induced immunodeficiency (MAIDS). (9380340)
1997
42
Convenient twice daily foscarnet in induction therapy of AIDS-associated cytomegalovirus retinitis. The Foscarnet Italian Study Group. (9030380)
1997
43
Cytomegalovirus retinitis: diagnosis and status of systemic therapy. (9058611)
1997
44
An economic evaluation of oral compared with intravenous ganciclovir for maintenance treatment of newly diagnosed cytomegalovirus retinitis in AIDS patients. (8829030)
1996
45
Cytomegalovirus retinitis and viral resistance. Prevalence of resistance at diagnosis, 1994. Cytomegalovirus Retinitis and Viral Resistance Study Group. (8660163)
1996
46
Treatment of cytomegalovirus retinitis: A growing number of options. (22514462)
1996
47
Long survival in AIDS-related cytomegalovirus retinitis. (8680895)
1996
48
Effectiveness of entoptic perimetry for locating peripheral scotomas caused by cytomegalovirus retinitis. (8660166)
1996
49
Treatment of cytomegalovirus retinitis in patients with AIDS. (8678370)
1996
50
Effect of foscarnet therapy on human immunodeficiency virus p24 antigen levels in AIDS patients with cytomegalovirus retinitis. (1323624)
1992

Variations for Cytomegalovirus Retinitis

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Expression for genes affiliated with Cytomegalovirus Retinitis

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Expression patterns in normal tissues for genes affiliated with Cytomegalovirus Retinitis

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Pathways for genes affiliated with Cytomegalovirus Retinitis

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Pathways related to Cytomegalovirus Retinitis according to GeneCards/GeneDecks:

(show top 50)    (show all 56)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7CCR5, CCR2, CXCL12
29.3HLA-DQB1, HLA-DRB1, IL10
3
Show member pathways
Immune response IL 22 signaling pathway60
G protein signaling N RAS regulation pathway60
9.3IL2, HLA-DRB1, HLA-DQB1
4
Show member pathways
9.3IL2, HLA-DRB1, HLA-DQB1
59.0CSF2, IL2, IFNG
69.0HLA-B, HLA-A, HLA-DQB1, HLA-DRB1
79.0HLA-B, HLA-A, HLA-DQB1, HLA-DRB1
8
Show member pathways
9.0HLA-B, HLA-A, HLA-DQB1, HLA-DRB1
99.0IL10RA, IL10, TNF
109.0IL2, IFNG, HLA-DRB1
118.9IFNG, IL2, IL10
128.8IFNG, CCR2, TNF
138.8IFNG, FASLG, TNF
14
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
8.8TNF, FASLG, IFNG
15
Show member pathways
8.7HLA-A, HLA-DQB1, TNF, FASLG
168.7FASLG, CXCL12, CCR2, IL2, IL10
178.6IL10, IFNG, TNF
188.5IL2, IFNG, TNF
198.5HLA-DRB1, TNF, CSF2, CD9
20
Show member pathways
Type III interferon signaling37
8.4CSF2, IL10RA, IL10, IL2, IFNG
218.3TNF, FASLG, IFNG, IL10
228.3CSF2, IL10, IFNG, TNF
238.3TNF, CCR2, IFNG, IL2
24
Show member pathways
Immune response IL 12 induced IFN gamma production60
8.1HLA-A, HLA-DRB1, FASLG, CCR5, IFNG, IL2
25
Show member pathways
IL27-mediated signaling events37
8.1TNF, IFNG, IL2, IL10
268.1TNF, IFNG, IL2, IL10
27
Show member pathways
Proteasome Degradation37
Immune response Antigen presentation by MHC class I60
8.0HLA-B, HLA-A, TNF, FASLG, IFNG
28
Show member pathways
Calcium signaling in the CD4+ TCR pathway37
8.0TNF, FASLG, IFNG, IL2, CSF2
29
Show member pathways
Ras signaling in the CD4+ TCR pathway37
7.9HLA-A, TNF, FASLG, IFNG, IL2
30
Show member pathways
7.9HLA-DQB1, HLA-DRB1, TNF, IFNG, IL10
31
Show member pathways
IL23-mediated signaling events37
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling37
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
7.8TNF, IFNG, IL2, IL10, IL10RA
32
Show member pathways
7.8IL2, IFNG, TNF, HLA-DRB1, HLA-DQB1
33
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
7.8IL10, IL2, IFNG, FASLG, TNF
347.8HLA-DQB1, HLA-DRB1, TNF, CXCL12, IFNG, CSF2
357.7HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, IFNG, IL10
367.6HLA-DQB1, HLA-DRB1, TNF, IFNG, IL10, IL10RA
37
Show member pathways
7.6HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, IFNG, IL2
38
Show member pathways
7.5TNF, CXCL12, IFNG, IL2, IL10, IL10RA
39
Show member pathways
7.5TNF, FASLG, IFNG, IL2, IL10, CSF2
40
Show member pathways
BCR signaling pathway37
TCR Signaling Pathway37
7.5TNF, CCR5, IFNG, IL2, IL10, CSF2
417.4HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, TNF, IL2
427.4HLA-DRB1, TNF, IFNG, IL2, IL10, CSF2
43
Show member pathways
7.4TNF, CSF2, IL10RA, IL10, IL2, CCR5
44
Show member pathways
7.4TNF, CXCL12, CCR2, CCR5, IL2, IL10
45
Show member pathways
7.4IL10RA, IL10, IL2, CCR5, CCR2, CXCL12
46
Show member pathways
Immune response CD16 signaling in NK cells60
7.2HLA-B, HLA-A, TNF, FASLG, IFNG, IL2
47
Show member pathways
6.9HLA-DQB1, HLA-DRB1, TNF, CCR5, IFNG, IL2
48
Show member pathways
6.8HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, TNF, FASLG
49
Show member pathways
6.5TNF, FASLG, CXCL12, CCR2, CCR5, IFNG
50
Show member pathways
5.8IL10RA, HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, TNF

Compounds for genes affiliated with Cytomegalovirus Retinitis

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Compounds related to Cytomegalovirus Retinitis according to GeneCards/GeneDecks:

(show top 50)    (show all 173)
idCompoundScoreTop Affiliating Genes
1mdms449.1CXCL12, IL10, CD9, CSF2, CCR5
2mip 1alpha449.0CSF2, IL10, CCR5, TNF
3glatiramer acetate44 119.8IL10, IL2, HLA-DRB1, IFNG
4cyclophosphamide44 50 1110.8CXCL12, CSF2, IL2, IL10, FASLG
5groalpha448.7CSF2, TNF, CXCL12, CCR5, IL10
6polysaccharide448.7CSF2, HLA-B, FASLG, CXCL12, CCR5, CD9
75-aza-2deoxycytidine448.5IFNG, HLA-B, HLA-A, CXCL12, FASLG
8zidovudine44 50 1110.5CXCL12, CSF2, IL10, IL2, CCR5, CD9
9ifn-alpha448.5CSF2, IL10, IL2, IFNG, CXCL12, FASLG
10gold sodium thiomalate448.5HLA-DRB1, TNF, IFNG, IL2
11imiquimod44 61 28 1111.5IL10, CSF2, IFNG, FASLG, TNF
125fluorouracil448.5CXCL12, FASLG, HLA-A, IFNG, IL2, CSF2
13interferon gamma448.4IFNG, IL2, IL10, TNF
14ribavirin44 50 1110.4CSF2, IFNG, IL10, CCR5, HLA-B, IL2
15ccl344 289.3IL10, CXCL12, CCR5, IFNG, TNF
16rapamycin448.3IFNG, IL10, IL2, CCR5, CXCL12, FASLG
17cimetidine44 28 1110.3HLA-B, IL10, CD9, IL2
18rituximab44 50 1110.3TNF, CSF2, IL10, IL2, CXCL12, FASLG
19simvastatin44 50 61 28 24 1113.3IL10, TNF, IFNG, CCR5, FASLG
20ivig448.2IL10, CCR5, FASLG, IFNG, CSF2, TNF
21rolipram44 61 2810.2TNF, IFNG, IL10, CD9
22il-12448.2CSF2, IL10, IL2, IFNG, TNF
23tarc448.2TNF, CSF2, IL10, IFNG, CCR5, CXCL12
24okt3448.2CSF2, IL10, IL2, IFNG, TNF
25gm-csf44 289.2IL10, IFNG, IL2, TNF, CSF2
26herbimycin a44 619.1IL2, TNF, CXCL12, IFNG, CSF2
27hydrocortisone44 2 61 1111.0CSF2, IL2, IL10, IFNG, TNF
28sb 20358044 619.0IL10, TNF, FASLG, CSF2, CXCL12, IFNG
29polyinosinic-polycytidylic acid448.0IFNG, IL10, IL2, TNF, HLA-B
302,5-oligoadenylate448.0IL2, IFNG, TNF, HLA-B, IL10
31endotoxin448.0IL10, CSF2, IFNG, TNF, HLA-B, FASLG
32mycophenolate mofetil44 50 1110.0TNF, IFNG, IL10, IL2
33thalidomide44 50 61 1110.9CSF2, IL10, IL2, IFNG, FASLG, TNF
34ionomycin447.9TNF, CSF2, IFNG, IL10, IL2, FASLG
35calcitriol44 61 24 1110.8CSF2, IL10, IFNG, TNF, IL2
36actinomycin d447.8IL2, FASLG, CXCL12, TNF, IFNG, CCR5
37histamine44 28 249.7TNF, CSF2, IL10, IL2, IFNG, CCR5
38il 10447.7IFNG, CCR5, TNF, CSF2, IL10RA, IL10
39pentoxifylline44 118.7CSF2, CD9, IFNG, IL2, IL10, TNF
40neopterin447.7CSF2, IFNG, CD9, TNF, IL10, IL2
41cycloheximide447.5TNF, FASLG, IFNG, IL2, IL10, CSF2
42genistein44 28 61 2 24 1112.5IL2, CD9, CSF2, CXCL12, TNF, FASLG
43tacrolimus44 50 119.5IL10, IL2, HLA-A, FASLG, HLA-B, TNF
44vegf447.3CXCL12, IFNG, IL2, IL10, TNF, CSF2
45thymidine44 248.1IL2, CXCL12, TNF, FASLG, IFNG, IL10
46tyrosine447.0IL2, HLA-B, HLA-DQB1, HLA-DRB1, CXCL12, IL10RA
47pge2447.0IL2, TNF, FASLG, CCR5, IFNG, IL10
48dexamethasone44 50 28 119.9HLA-B, IL10, IL2, IFNG, CCR5, CXCL12
49cyclosporin a44 28 618.9HLA-B, TNF, CSF2, FASLG, CCR5, IFNG
50rantes446.5HLA-B, CCR5, CXCL12, TNF, IL2, CSF2

GO Terms for genes affiliated with Cytomegalovirus Retinitis

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Cellular components related to Cytomegalovirus Retinitis according to GeneCards/GeneDecks:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1MHC class I protein complexGO:0426129.6HLA-B, HLA-A
2MHC class II protein complexGO:0426139.5HLA-DRB1, HLA-DQB1
3integral component of lumenal side of endoplasmic reticulum membraneGO:0715569.2HLA-DRB1, HLA-DQB1, HLA-A, HLA-B
4ER to Golgi transport vesicle membraneGO:0125079.2HLA-B, HLA-A, HLA-DQB1, HLA-DRB1
5Golgi membraneGO:0001399.0HLA-DRB1, HLA-DQB1, HLA-A, HLA-B
6cell surfaceGO:0099868.6CCR5, TNF, HLA-A, HLA-B
7extracellular regionGO:0055767.7TNF, FASLG, CXCL12, IFNG, IL2, CSF2
8external side of plasma membraneGO:0098977.6CD9, HLA-DRB1, TNF, FASLG, CXCL12, CCR5
9integral component of plasma membraneGO:0058877.4HLA-B, HLA-A, HLA-DRB1, TNF, FASLG, CCR2
10extracellular spaceGO:0056157.4TNF, FASLG, CXCL12, IFNG, IL2, IL10
11plasma membraneGO:0058867.1HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, TNF, CCR2

Biological processes related to Cytomegalovirus Retinitis according to GeneCards/GeneDecks:

(show all 40)
idNameGO IDScoreTop Affiliating Genes
1dendritic cell chemotaxisGO:00240710.2CCR5, CCR2
2immunoglobulin production involved in immunoglobulin mediated immune responseGO:00238110.1HLA-DQB1, HLA-DRB1
3antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independentGO:00248610.1HLA-A, HLA-B
4humoral immune response mediated by circulating immunoglobulinGO:00245510.1HLA-DRB1, HLA-DQB1
5positive regulation of monocyte chemotaxisGO:09002610.1CCR5, CCR2, CXCL12
6chemokine-mediated signaling pathwayGO:07009810.1CCR5, CCR2, CXCL12
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentGO:00248010.0HLA-B, HLA-A
8positive regulation of interleukin-23 productionGO:0327479.9IFNG, CSF2
9chemotaxisGO:0069359.9CXCL12, CCR2, CCR5
10positive regulation of tyrosine phosphorylation of Stat5 proteinGO:0425239.9IL2, CSF2
11positive regulation of T cell mediated cytotoxicityGO:0019169.8HLA-B, HLA-A
12detection of bacteriumGO:0160459.8HLA-B, HLA-A, HLA-DRB1
13necroptotic signaling pathwayGO:0975279.8TNF, FASLG
14positive regulation of podosome assemblyGO:0718039.7TNF, CSF2
15positive regulation of cytosolic calcium ion concentrationGO:0072049.7IL2, CCR5, CCR2
16positive regulation of MHC class II biosynthetic processGO:0453489.7IL10, IFNG
17positive regulation of isotype switching to IgG isotypesGO:0483049.7IFNG, IL2
18receptor biosynthetic processGO:0328009.6IL10, TNF
19negative regulation of cytokine secretion involved in immune responseGO:0027409.6TNF, IL10
20negative regulation of interferon-gamma productionGO:0326899.5IL10, HLA-DRB1
21positive regulation of vitamin D biosynthetic processGO:0605579.4IFNG, TNF
22positive regulation of calcidiol 1-monooxygenase activityGO:0605599.4IFNG, TNF
23cell-cell signalingGO:0072679.3FASLG, CCR5, IL2, IL10
24negative regulation of interleukin-6 productionGO:0327159.3TNF, IL10
25positive regulation of chemokine biosynthetic processGO:0450809.3IFNG, TNF
26positive regulation of membrane protein ectodomain proteolysisGO:0510449.3IFNG, TNF
27cellular response to lipopolysaccharideGO:0712229.3CCR5, IFNG, IL10, CSF2
28viral processGO:0160329.2HLA-B, HLA-A, CCR2, CCR5
29positive regulation of osteoclast differentiationGO:0456729.2IFNG, TNF
30response to activityGO:0148239.2IL10, TNF
31extrinsic apoptotic signaling pathwayGO:0971919.2TNF, FASLG, IFNG
32protein import into nucleus, translocationGO:0000609.1IFNG, TNF
33inflammatory responseGO:0069549.0TNF, CCR2, CCR5, IL10
34response to virusGO:0096159.0IFNG, CXCL12, TNF
35negative regulation of growth of symbiont in hostGO:0441309.0TNF, IFNG, IL10
36positive regulation of interferon-gamma productionGO:0327299.0HLA-A, TNF, CCR2, IL2
37positive regulation of cytokine secretionGO:0507158.9IL10, TNF
38interferon-gamma-mediated signaling pathwayGO:0603338.8HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, IFNG
39cytokine-mediated signaling pathwayGO:0192218.4HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, CCR2, IFNG
40immune responseGO:0069557.6CSF2, HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, FASLG

Molecular functions related to Cytomegalovirus Retinitis according to GeneCards/GeneDecks:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1C-C chemokine receptor activityGO:01649310.0CCR2, CCR5
2TAP bindingGO:0469779.8HLA-B, HLA-A
3MHC class II receptor activityGO:0323959.7HLA-DRB1, HLA-DQB1
4chemokine receptor activityGO:0049509.7CCR5, CCR2
5peptide antigen bindingGO:0426059.5HLA-B, HLA-A, HLA-DRB1
6tumor necrosis factor receptor bindingGO:0051649.4FASLG, TNF
7receptor bindingGO:0051029.2CXCL12, FASLG, HLA-A, HLA-B
8growth factor activityGO:0080839.1CSF2, IL10, IL2, CXCL12
9cytokine activityGO:0051257.7CSF2, IL10, IL2, IFNG, FASLG, TNF

Products for genes affiliated with Cytomegalovirus Retinitis

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Sources for Cytomegalovirus Retinitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
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51PubMed
52QIAGEN
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62UMLS
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