MCID: CYT005
MIFTS: 48

Cytomegalovirus Retinitis malady

Rare diseases category

Summaries for Cytomegalovirus Retinitis

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Wikipedia:63 Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that... more...

MalaCards based summary: Cytomegalovirus Retinitis is related to intraocular lymphoma and acquired immunodeficiency syndrome. An important gene associated with Cytomegalovirus Retinitis is IL10RA (interleukin 10 receptor, alpha), and among its related pathways are Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions and Staphylococcus aureus infection. The drugs ganciclovir and ganciclovir sodium and the compounds mdms and mip 1alpha have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and t cells, and related mouse phenotypes are renal/urinary system and vision/eye.

Aliases & Classifications for Cytomegalovirus Retinitis

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Cytomegalovirus Retinitis, Aliases & Descriptions:

Name: Cytomegalovirus Retinitis 41 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Related Diseases for Cytomegalovirus Retinitis

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Diseases related to Cytomegalovirus Retinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 152)
idRelated DiseaseScoreTop Affiliating Genes
1intraocular lymphoma30.8IL10
2acquired immunodeficiency syndrome30.7HLA-B, CSF2, IL2, CCR5, CCR2, CXCL12
3encephalitis30.4CD9, CCR5, HLA-B
4leprosy30.4HLA-DRB1, IL2
5tuberculoid leprosy30.1IL10, IFNG
6common variable immunodeficiency30.1IL2, IL10
7aplastic anemia30.1FASLG, IFNG, CSF2
8uveitis30.1TNF, HLA-A, HLA-B, CCR5, IL10, IFNG
9pneumonia30.0CSF2, TNF, IL10, CD9
10myeloma29.6CXCL12, HLA-B, FASLG, IL2, CSF2, CD9
11leukemia28.7IFNG, CD9, CSF2, HLA-DRB1, TNF, HLA-B
12arthritis28.7CCR5, TNF, IL10, IFNG, CSF2, HLA-A
13systemic lupus erythematosus28.6IL10RA, IL10, IL2, IFNG, CCR5, HLA-A
14tuberculosis28.3IL10, IL2, IFNG, CXCL12, HLA-A, HLA-DQB1
15rheumatoid arthritis27.8IL2, CXCL12, CCR5, IFNG, IL10, IL10RA
16retinitis11.4
17retinal detachment10.7
18periapical granuloma10.6CCR5
19hypersensitivity syndrome, carbamazepine-induced10.5FASLG
20felty's syndrome10.5CSF2
21aphthous stomatitis10.4HLA-B
22thyroiditis10.4FASLG, HLA-DRB1
23blau syndrome10.4TNF
24hematopoietic stem cell transplantation10.4
25vogt-koyanagi-harada disease10.3FASLG, HLA-DRB1
26multiple sclerosis, disease progression, modifier of10.3HLA-DRB1, HLA-DQB1
27stomatitis10.3CSF2
28retinal vein occlusion10.3
29good syndrome10.3
30central retinal vein occlusion10.3
31lupus erythematosus10.3
32lymphoblastic leukemia10.3
33choroiditis10.3
34anterior uveitis10.3
35congenital cytomegalovirus10.3
36human immunodeficiency virus infectious disease10.3HLA-A, FASLG
37autoimmune lymphoproliferative syndrome10.3IL10, FASLG
38capillary leak syndrome10.2CSF2, IL2
39choriocarcinoma10.2FASLG, CD9, CSF2
40agammaglobulinemia10.2IL2, CXCL12
41dementia10.2CD9, CCR5, CXCL12
42familial mediterranean fever, ar10.2TNF, HLA-A
43hepatitis10.2HLA-A, FASLG, HLA-DRB1
44alcoholic hepatitis10.2IL10, TNF
45aids dementia complex10.2CCR5, TNF, CXCL12
46cataract10.2
47neuritis10.2
48optic neuritis10.2
49cytomegalovirus infection10.2
50blindness10.2

Graphical network of the top 20 diseases related to Cytomegalovirus Retinitis:



Diseases related to cytomegalovirus retinitis

Symptoms for Cytomegalovirus Retinitis

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Drugs & Therapeutics for Cytomegalovirus Retinitis

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Drug clinical trials:

Search ClinicalTrials for Cytomegalovirus Retinitis

Search NIH Clinical Center for Cytomegalovirus Retinitis

Inferred drug relations via UMLS60/NDF-RT39:

Genetic Tests for Cytomegalovirus Retinitis

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Anatomical Context for Cytomegalovirus Retinitis

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MalaCards organs/tissues related to Cytomegalovirus Retinitis:

31
Eye, Retina, T cells, Bone, Bone marrow, Testes, Liver, Endothelial, Heart, Lung, Nk cells

Animal Models for Cytomegalovirus Retinitis or affiliated genes

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MGI Mouse Phenotypes related to Cytomegalovirus Retinitis:

35 (show all 20)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.8CSF2, CCR2, FASLG, HLA-DQB1, IFNG
2MP:00053917.8IL10, IFNG, TNF, FASLG, CCR5, CCR2
3MP:00053697.6IFNG, HLA-DQB1, TNF, CXCL12, CCR5, IL10
4MP:00053907.3TNF, FASLG, CCR2, IFNG, IL10, CSF2
5MP:00053797.3CSF2, IL10, IL2, FASLG, TNF, HLA-DQB1
6MP:00020067.3IFNG, IL2, CSF2, IL10, CCR5, CCR2
7MP:00030127.1HLA-B, TNF, CXCL12, CCR2, CCR5, IFNG
8MP:00053817.0IL10, CCR2, HLA-DQB1, FASLG, IL2, IFNG
9MP:00053707.0CXCL12, HLA-DQB1, TNF, FASLG, IL2, CCR2
10MP:00036316.9HLA-B, IL10, IFNG, CCR5, CCR2, TNF
11MP:00053886.7IFNG, IL2, FASLG, TNF, HLA-DQB1, CCR2
12MP:00053866.7HLA-B, HLA-DQB1, IL10, IL2, TNF, CSF2
13MP:00053766.7TNF, FASLG, IFNG, CCR2, IL2, IL10
14MP:00053856.6CXCL12, CCR2, IFNG, IL10, CSF2, FASLG
15MP:00053846.4IL2, CCR2, IFNG, CSF2, CXCL12, IL10RA
16MP:00053896.4IL10, IL2, IFNG, CCR5, CXCL12, FASLG
17MP:00053786.4IFNG, CSF2, TNF, CD9, IL2, IL10
18MP:00107686.2CSF2, CXCL12, CCR5, HLA-B, HLA-DQB1, TNF
19MP:00053975.6CCR5, CSF2, IL10RA, IL10, HLA-B, HLA-DQB1
20MP:00053875.5HLA-DQB1, TNF, CSF2, IL10RA, IL10, IL2

Publications for Cytomegalovirus Retinitis

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Articles related to Cytomegalovirus Retinitis:

(show top 50)    (show all 526)
idTitleAuthorsYear
1
Cytomegalovirus Retinitis in a Human Immunodeficiency Virus-negative Cohort: Long-term Management and Complications. (25760914)
2015
2
Telemedicine diagnosis of cytomegalovirus retinitis by nonophthalmologists. (24945306)
2014
3
Herpetic (non-cytomegalovirus) retinal infections in patients with the acquired immunodeficiency syndrome. (23544389)
2013
4
A messenger at the door: cytomegalovirus retinitis in myeloma patients with progressive disease. (23790037)
2013
5
Telemedicine screening for cytomegalovirus retinitis using digital fundus photography. (23756239)
2013
6
Retinal metastasis simulating cytomegalovirus retinitis. (22938704)
2012
7
Risk factors for cytomegalovirus retinitis in patients with cytomegalovirus viremia after hematopoietic stem cell transplantation. (22657564)
2012
8
Evidence for multiple cell death pathways during development of experimental cytomegalovirus retinitis in mice with retrovirus-induced immunosuppression: apoptosis, necroptosis, and pyroptosis. (22837196)
2012
9
The epidemiology and incidence of cytomegalovirus retinitis in the HIV population in Singapore over 6 years. (23074211)
2012
10
Association of host genetic risk factors with the course of cytomegalovirus retinitis in patients infected with human immunodeficiency virus. (21396623)
2011
11
Cytomegalovirus retinitis in an immunocompromised infant: a case report and review of the literature. (21941498)
2011
12
Evaluation of the United States public health service guidelines for discontinuation of anticytomegalovirus therapy after immune recovery in patients with cytomegalovirus retinitis. (21742304)
2011
13
Mortality associated with resistant cytomegalovirus among patients with cytomegalovirus retinitis and AIDS. (19818505)
2010
14
Intravitreal ganciclovir in the management of non-AIDS-related human cytomegalovirus retinitis. (20379302)
2010
15
Good's syndrome in a patient with cytomegalovirus retinitis. (18382022)
2008
16
Increased incidence of cytomegalovirus retinitis after allogeneic hematopoietic stem cell transplantation. (17220797)
2007
17
Cytomegalovirus retinitis following intravitreal injection of triamcinolone: report of two cases. (17403022)
2007
18
Cytomegalovirus retinitis: the neglected disease of the AIDS pandemic. (18052600)
2007
19
Long-term follow-up of a cohort of HIV-infected patients who discontinued maintenance therapy for cytomegalovirus retinitis. (16632459)
2006
20
Indocyanine green angiographic findings in a cytomegalovirus retinitis patient. (16334614)
2005
21
A case of immune recovery vitritis induced by donor leukocyte infusion for the treatment of cytomegalovirus retinitis. (16146543)
2005
22
PCR with the aqueous humor, blood leukocytes and vitreous of patients affected by cytomegalovirus retinitis and immune recovery uveitis. (14688435)
2004
23
Human cytomegalovirus retinitis: pathogenicity, immune evasion and persistence. (12706995)
2003
24
Interleukin-2 immunotherapy of murine cytomegalovirus retinitis during MAIDS correlates with increased intraocular CD8+ T-cell infiltration. (12711843)
2003
25
Mortality risk for patients with cytomegalovirus retinitis and acquired immune deficiency syndrome. (14583871)
2003
26
Visual loss in patients with cytomegalovirus retinitis and acquired immunodeficiency syndrome before widespread availability of highly active antiretroviral therapy. (12523893)
2003
27
Murine cytomegalovirus retinitis during retrovirus-induced immunodeficiency (MAIDS) in mice: interleukin-2 immunotherapy correlates with increased intraocular levels of perforin mRNA. (12895694)
2003
28
Safety of intravitreous fomivirsen for treatment of cytomegalovirus retinitis in patients with AIDS. (11931782)
2002
29
HIV and cytomegalovirus viral load and clinical outcomes in AIDS and cytomegalovirus retinitis patients: Monoclonal Antibody Cytomegalovirus Retinitis Trial. (11919489)
2002
30
Protease inhibitor therapy is associated with markedly prolonged time to relapse and improved survival in AIDS patients with cytomegalovirus retinitis. (11564333)
2001
31
Cystoid macular edema in patients with acquired immune deficiency syndrome and cytomegalovirus retinitis. (11071031)
2000
32
Highly active antiretroviral therapy-related immune recovery in AIDS patients with cytomegalovirus retinitis. (10811078)
2000
33
HIV associated cytomegalovirus retinitis in Melbourne, Australia. (10961210)
2000
34
Visual and anatomic outcomes associated with posterior segment complications after ganciclovir implant procedures in patients with AIDS and cytomegalovirus retinitis. (10088738)
1999
35
Cystoid macular edema following immune recovery and treatment with cidofovir for cytomegalovirus retinitis. (10541898)
1999
36
Successive intraocular nocardiosis and cytomegalovirus retinitis after cardiac transplantation. (9682720)
1998
37
Optic nerve head neovascularization in a patient with inactive cytomegalovirus retinitis and immune recovery. (9727534)
1998
38
Iritis and hypotony after treatment with intravenous cidofovir for cytomegalovirus retinitis. (9194724)
1997
39
New therapies for cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. (9109331)
1997
40
Successful use of cidofovir in treating AIDS-related cytomegalovirus retinitis, encephalitis, and esophagitis. (9215660)
1997
41
Antibody alone does not prevent experimental cytomegalovirus retinitis in mice with retrovirus-induced immunodeficiency (MAIDS). (9380340)
1997
42
Convenient twice daily foscarnet in induction therapy of AIDS-associated cytomegalovirus retinitis. The Foscarnet Italian Study Group. (9030380)
1997
43
Cytomegalovirus retinitis: diagnosis and status of systemic therapy. (9058611)
1997
44
An economic evaluation of oral compared with intravenous ganciclovir for maintenance treatment of newly diagnosed cytomegalovirus retinitis in AIDS patients. (8829030)
1996
45
Cytomegalovirus retinitis and viral resistance. Prevalence of resistance at diagnosis, 1994. Cytomegalovirus Retinitis and Viral Resistance Study Group. (8660163)
1996
46
Treatment of cytomegalovirus retinitis: A growing number of options. (22514462)
1996
47
Long survival in AIDS-related cytomegalovirus retinitis. (8680895)
1996
48
Effectiveness of entoptic perimetry for locating peripheral scotomas caused by cytomegalovirus retinitis. (8660166)
1996
49
Treatment of cytomegalovirus retinitis in patients with AIDS. (8678370)
1996
50
Effect of foscarnet therapy on human immunodeficiency virus p24 antigen levels in AIDS patients with cytomegalovirus retinitis. (1323624)
1992

Variations for Cytomegalovirus Retinitis

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Expression for genes affiliated with Cytomegalovirus Retinitis

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Search GEO for disease gene expression data for Cytomegalovirus Retinitis.

Pathways for genes affiliated with Cytomegalovirus Retinitis

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Pathways related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7CCR5, CCR2, CXCL12
29.3HLA-DQB1, HLA-DRB1, IL10
3
Show member pathways
Immune response IL 22 signaling pathway58
G protein signaling N RAS regulation pathway58
9.3IL2, HLA-DRB1, HLA-DQB1
4
Show member pathways
9.3IL2, HLA-DRB1, HLA-DQB1
59.0CSF2, IL2, IFNG
69.0HLA-B, HLA-A, HLA-DQB1, HLA-DRB1
79.0HLA-B, HLA-A, HLA-DQB1, HLA-DRB1
8
Show member pathways
9.0HLA-B, HLA-A, HLA-DQB1, HLA-DRB1
99.0IL10RA, IL10, TNF
109.0IL2, IFNG, HLA-DRB1
118.9IFNG, IL2, IL10
128.8IFNG, CCR2, TNF
138.8IFNG, FASLG, TNF
14
Show member pathways
Transcription NF kB signaling pathway58
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response58
8.8TNF, FASLG, IFNG
15
Show member pathways
8.7HLA-A, HLA-DQB1, TNF, FASLG
168.7FASLG, CXCL12, CCR2, IL2, IL10
178.6IL10, IFNG, TNF
188.5IL2, IFNG, TNF
198.5HLA-DRB1, TNF, CSF2, CD9
20
Show member pathways
Type III interferon signaling36
8.4CSF2, IL10RA, IL10, IL2, IFNG
218.3TNF, FASLG, IFNG, IL10
228.3CSF2, IL10, IFNG, TNF
238.3TNF, CCR2, IFNG, IL2
24
Show member pathways
Immune response IL 12 induced IFN gamma production58
8.1HLA-A, HLA-DRB1, FASLG, CCR5, IFNG, IL2
25
Show member pathways
IL27-mediated signaling events36
8.1TNF, IFNG, IL2, IL10
268.1TNF, IFNG, IL2, IL10
27
Show member pathways
Proteasome Degradation36
Immune response Antigen presentation by MHC class I58
8.0HLA-B, HLA-A, TNF, FASLG, IFNG
28
Show member pathways
Calcium signaling in the CD4+ TCR pathway36
8.0TNF, FASLG, IFNG, IL2, CSF2
29
Show member pathways
Ras signaling in the CD4+ TCR pathway36
7.9HLA-A, TNF, FASLG, IFNG, IL2
30
Show member pathways
7.9HLA-DQB1, HLA-DRB1, TNF, IFNG, IL10
31
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
7.8TNF, IFNG, IL2, IL10, IL10RA
32
Show member pathways
7.8IL2, IFNG, TNF, HLA-DRB1, HLA-DQB1
33
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
7.8IL10, IL2, IFNG, FASLG, TNF
347.8HLA-DQB1, HLA-DRB1, TNF, CXCL12, IFNG, CSF2
357.7HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, IFNG, IL10
367.6HLA-DQB1, HLA-DRB1, TNF, IFNG, IL10, IL10RA
37
Show member pathways
7.6HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, IFNG, IL2
38
Show member pathways
7.5TNF, CXCL12, IFNG, IL2, IL10, IL10RA
39
Show member pathways
7.5TNF, FASLG, IFNG, IL2, IL10, CSF2
40
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
7.5TNF, CCR5, IFNG, IL2, IL10, CSF2
417.4HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, TNF, IL2
427.4HLA-DRB1, TNF, IFNG, IL2, IL10, CSF2
43
Show member pathways
7.4TNF, CSF2, IL10RA, IL10, IL2, CCR5
44
Show member pathways
7.4TNF, CXCL12, CCR2, CCR5, IL2, IL10
45
Show member pathways
7.4IL10RA, IL10, IL2, CCR5, CCR2, CXCL12
46
Show member pathways
Immune response CD16 signaling in NK cells58
7.2HLA-B, HLA-A, TNF, FASLG, IFNG, IL2
47
Show member pathways
6.9HLA-DQB1, HLA-DRB1, TNF, CCR5, IFNG, IL2
48
Show member pathways
6.8HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, TNF, FASLG
49
Show member pathways
6.5TNF, FASLG, CXCL12, CCR2, CCR5, IFNG
50
Show member pathways
5.8IL10RA, HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, TNF

Compounds for genes affiliated with Cytomegalovirus Retinitis

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Compounds related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 173)
idCompoundScoreTop Affiliating Genes
1mdms439.1CXCL12, IL10, CD9, CSF2, CCR5
2mip 1alpha439.0CSF2, IL10, CCR5, TNF
3glatiramer acetate43 129.8IL10, IL2, HLA-DRB1, IFNG
4cyclophosphamide43 49 1210.8CXCL12, CSF2, IL2, IL10, FASLG
5groalpha438.7CSF2, TNF, CXCL12, CCR5, IL10
6polysaccharide438.7CSF2, HLA-B, FASLG, CXCL12, CCR5, CD9
75-aza-2deoxycytidine438.5IFNG, HLA-B, HLA-A, CXCL12, FASLG
8zidovudine43 49 1210.5CXCL12, CSF2, IL10, IL2, CCR5, CD9
9ifn-alpha438.5CSF2, IL10, IL2, IFNG, CXCL12, FASLG
10gold sodium thiomalate438.5HLA-DRB1, TNF, IFNG, IL2
11imiquimod43 59 28 1211.5IL10, CSF2, IFNG, FASLG, TNF
125fluorouracil438.5CXCL12, FASLG, HLA-A, IFNG, IL2, CSF2
13interferon gamma438.4IFNG, IL2, IL10, TNF
14ribavirin43 49 1210.4CSF2, IFNG, IL10, CCR5, HLA-B, IL2
15ccl343 289.3IL10, CXCL12, CCR5, IFNG, TNF
16rapamycin438.3IFNG, IL10, IL2, CCR5, CXCL12, FASLG
17cimetidine43 28 1210.3HLA-B, IL10, CD9, IL2
18rituximab43 49 1210.3TNF, CSF2, IL10, IL2, CXCL12, FASLG
19simvastatin43 49 59 28 24 1213.3IL10, TNF, IFNG, CCR5, FASLG
20ivig438.2IL10, CCR5, FASLG, IFNG, CSF2, TNF
21rolipram43 59 2810.2TNF, IFNG, IL10, CD9
22il-12438.2CSF2, IL10, IL2, IFNG, TNF
23tarc438.2TNF, CSF2, IL10, IFNG, CCR5, CXCL12
24okt3438.2CSF2, IL10, IL2, IFNG, TNF
25gm-csf43 289.2IL10, IFNG, IL2, TNF, CSF2
26herbimycin a43 599.1IL2, TNF, CXCL12, IFNG, CSF2
27hydrocortisone43 2 59 1211.0CSF2, IL2, IL10, IFNG, TNF
28sb 20358043 599.0IL10, TNF, FASLG, CSF2, CXCL12, IFNG
29polyinosinic-polycytidylic acid438.0IFNG, IL10, IL2, TNF, HLA-B
302,5-oligoadenylate438.0IL2, IFNG, TNF, HLA-B, IL10
31endotoxin438.0IL10, CSF2, IFNG, TNF, HLA-B, FASLG
32mycophenolate mofetil43 49 1210.0TNF, IFNG, IL10, IL2
33thalidomide43 49 59 1210.9CSF2, IL10, IL2, IFNG, FASLG, TNF
34ionomycin437.9TNF, CSF2, IFNG, IL10, IL2, FASLG
35calcitriol43 59 24 1210.8CSF2, IL10, IFNG, TNF, IL2
36actinomycin d437.8IL2, FASLG, CXCL12, TNF, IFNG, CCR5
37histamine43 28 249.7TNF, CSF2, IL10, IL2, IFNG, CCR5
38il 10437.7IFNG, CCR5, TNF, CSF2, IL10RA, IL10
39pentoxifylline43 128.7CSF2, CD9, IFNG, IL2, IL10, TNF
40neopterin437.7CSF2, IFNG, CD9, TNF, IL10, IL2
41cycloheximide437.5TNF, FASLG, IFNG, IL2, IL10, CSF2
42genistein43 28 59 2 24 1212.5IL2, CD9, CSF2, CXCL12, TNF, FASLG
43tacrolimus43 49 129.5IL10, IL2, HLA-A, FASLG, HLA-B, TNF
44vegf437.3CXCL12, IFNG, IL2, IL10, TNF, CSF2
45thymidine43 248.1IL2, CXCL12, TNF, FASLG, IFNG, IL10
46tyrosine437.0IL2, HLA-B, HLA-DQB1, HLA-DRB1, CXCL12, IL10RA
47pge2437.0IL2, TNF, FASLG, CCR5, IFNG, IL10
48dexamethasone43 49 28 129.9HLA-B, IL10, IL2, IFNG, CCR5, CXCL12
49cyclosporin a43 28 598.9HLA-B, TNF, CSF2, FASLG, CCR5, IFNG
50rantes436.5HLA-B, CCR5, CXCL12, TNF, IL2, CSF2

GO Terms for genes affiliated with Cytomegalovirus Retinitis

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Cellular components related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1MHC class I protein complexGO:00426129.6HLA-B, HLA-A
2MHC class II protein complexGO:00426139.5HLA-DRB1, HLA-DQB1
3integral component of lumenal side of endoplasmic reticulum membraneGO:00715569.2HLA-DRB1, HLA-DQB1, HLA-A, HLA-B
4ER to Golgi transport vesicle membraneGO:00125079.2HLA-B, HLA-A, HLA-DQB1, HLA-DRB1
5Golgi membraneGO:00001399.0HLA-DRB1, HLA-DQB1, HLA-A, HLA-B
6cell surfaceGO:00099868.6CCR5, TNF, HLA-A, HLA-B
7extracellular regionGO:00055767.7TNF, FASLG, CXCL12, IFNG, IL2, CSF2
8external side of plasma membraneGO:00098977.6CD9, HLA-DRB1, TNF, FASLG, CXCL12, CCR5
9integral component of plasma membraneGO:00058877.4HLA-B, HLA-A, HLA-DRB1, TNF, FASLG, CCR2
10extracellular spaceGO:00056157.4TNF, FASLG, CXCL12, IFNG, IL2, IL10
11plasma membraneGO:00058867.1HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, TNF, CCR2

Biological processes related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

(show all 40)
idNameGO IDScoreTop Affiliating Genes
1dendritic cell chemotaxisGO:000240710.2CCR5, CCR2
2immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238110.1HLA-DQB1, HLA-DRB1
3antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independentGO:000248610.1HLA-A, HLA-B
4humoral immune response mediated by circulating immunoglobulinGO:000245510.1HLA-DRB1, HLA-DQB1
5positive regulation of monocyte chemotaxisGO:009002610.1CCR5, CCR2, CXCL12
6chemokine-mediated signaling pathwayGO:007009810.1CCR5, CCR2, CXCL12
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentGO:000248010.0HLA-B, HLA-A
8positive regulation of interleukin-23 productionGO:00327479.9IFNG, CSF2
9chemotaxisGO:00069359.9CXCL12, CCR2, CCR5
10positive regulation of tyrosine phosphorylation of Stat5 proteinGO:00425239.9IL2, CSF2
11positive regulation of T cell mediated cytotoxicityGO:00019169.8HLA-B, HLA-A
12detection of bacteriumGO:00160459.8HLA-B, HLA-A, HLA-DRB1
13necroptotic signaling pathwayGO:00975279.8TNF, FASLG
14positive regulation of podosome assemblyGO:00718039.7TNF, CSF2
15positive regulation of cytosolic calcium ion concentrationGO:00072049.7IL2, CCR5, CCR2
16positive regulation of MHC class II biosynthetic processGO:00453489.7IL10, IFNG
17positive regulation of isotype switching to IgG isotypesGO:00483049.7IFNG, IL2
18receptor biosynthetic processGO:00328009.6IL10, TNF
19negative regulation of cytokine secretion involved in immune responseGO:00027409.6TNF, IL10
20negative regulation of interferon-gamma productionGO:00326899.5IL10, HLA-DRB1
21positive regulation of vitamin D biosynthetic processGO:00605579.4IFNG, TNF
22positive regulation of calcidiol 1-monooxygenase activityGO:00605599.4IFNG, TNF
23cell-cell signalingGO:00072679.3FASLG, CCR5, IL2, IL10
24negative regulation of interleukin-6 productionGO:00327159.3TNF, IL10
25positive regulation of chemokine biosynthetic processGO:00450809.3IFNG, TNF
26positive regulation of membrane protein ectodomain proteolysisGO:00510449.3IFNG, TNF
27cellular response to lipopolysaccharideGO:00712229.3CCR5, IFNG, IL10, CSF2
28viral processGO:00160329.2HLA-B, HLA-A, CCR2, CCR5
29positive regulation of osteoclast differentiationGO:00456729.2IFNG, TNF
30response to activityGO:00148239.2IL10, TNF
31extrinsic apoptotic signaling pathwayGO:00971919.2TNF, FASLG, IFNG
32protein import into nucleus, translocationGO:00000609.1IFNG, TNF
33inflammatory responseGO:00069549.0TNF, CCR2, CCR5, IL10
34response to virusGO:00096159.0IFNG, CXCL12, TNF
35negative regulation of growth of symbiont in hostGO:00441309.0TNF, IFNG, IL10
36positive regulation of interferon-gamma productionGO:00327299.0HLA-A, TNF, CCR2, IL2
37positive regulation of cytokine secretionGO:00507158.9IL10, TNF
38interferon-gamma-mediated signaling pathwayGO:00603338.8HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, IFNG
39cytokine-mediated signaling pathwayGO:00192218.4HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, CCR2, IFNG
40immune responseGO:00069557.6CSF2, HLA-B, HLA-A, HLA-DQB1, HLA-DRB1, FASLG

Molecular functions related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1C-C chemokine receptor activityGO:001649310.0CCR2, CCR5
2TAP bindingGO:00469779.8HLA-B, HLA-A
3MHC class II receptor activityGO:00323959.7HLA-DRB1, HLA-DQB1
4chemokine receptor activityGO:00049509.7CCR5, CCR2
5peptide antigen bindingGO:00426059.5HLA-B, HLA-A, HLA-DRB1
6tumor necrosis factor receptor bindingGO:00051649.4FASLG, TNF
7receptor bindingGO:00051029.2CXCL12, FASLG, HLA-A, HLA-B
8growth factor activityGO:00080839.1CSF2, IL10, IL2, CXCL12
9cytokine activityGO:00051257.7CSF2, IL10, IL2, IFNG, FASLG, TNF

Products for genes affiliated with Cytomegalovirus Retinitis

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3CDC
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