MCID: CYT005
MIFTS: 52

Cytomegalovirus Retinitis malady

Summaries for Cytomegalovirus Retinitis

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that... more...

MalaCards: Cytomegalovirus Retinitis is related to acquired immunodeficiency syndrome and uveitis. An important gene associated with Cytomegalovirus Retinitis is IL10RA (interleukin 10 receptor, alpha), and among its related pathways are Rheumatoid arthritis and Cytokines and Inflammatory Response. The drugs ganciclovir and ganciclovir sodium and the compounds endotoxin and tacrolimus have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, retina and heart, and related mouse phenotypes are no phenotypic analysis and nervous system.

Aliases & Classifications for Cytomegalovirus Retinitis

Sources:
43NIH Rare Diseases, 61UMLS
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Aliases & Descriptions:

cytomegalovirus retinitis 43 61


Related Diseases for Cytomegalovirus Retinitis

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Cytomegalovirus Retinitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 241)
idRelated DiseaseScoreTop Affiliating Genes
1acquired immunodeficiency syndrome31.0IL2, CXCL12, HLA-B, CSF2, CCR5, CCR2
2uveitis30.9IL10, HLA-A, HLA-B, TNF, IFNG, CCR5
3acute leukemia30.4IL2, CXCL12, HDAC9, CSF2
4systemic lupus erythematosus30.4IL2, IL10, IL10RA, HLA-A, HLA-DRB1, HLA-DQB1
5intraocular lymphoma30.2IL10
6herpes zoster30.0CD9
7thymoma30.0IL2
8thrombocytopenia30.0IL2, CSF2
9aplastic anemia30.0FASLG, CSF2, IFNG
10vasculitis30.0HLA-B, TNF
11tuberculoid leprosy29.9IL10, IFNG
12t-cell leukemia29.9IL2, HDAC9, HLA-B, FASLG
13tuberculosis29.9IL2, IL10, CXCL12, CD9, HLA-A, HLA-DRB1
14arthritis29.9IL10, HDAC9, HLA-A, HLA-DRB1, HLA-B, TNF
15cytomegalovirus infection10.5
16cystoid macular edema10.4
17good syndrome10.4
18central retinal vein occlusion10.3
19anterior uveitis10.3
20hematopoietic stem cell transplantation10.3
21n syndrome10.2
22congenital cytomegalovirus10.2
23common variable immunodeficiency10.1
24vein disease10.1
25iritis10.0
26choroiditis10.0
27acute t cell leukemia10.0
28acute retinal necrosis syndrome10.0
29diabetes insipidus10.0
30nocardiosis10.0
31scotoma10.0
32nephrogenic diabetes insipidus10.0
33posterior uveitis10.0
34hemophilia10.0
35char syndrome10.0
36acute lymphoblastic leukemia, childhood10.0
37charles bonnet syndrome10.0
38blindness10.0
39toxoplasmosis10.0CD9
40sjogren's syndrome10.0FASLG
41myocarditis10.0IFNB1
42optic neuritis10.0IFNB1
43chagas disease10.0CCR5
44toxic epidermal necrolysis10.0FASLG
45guillain-barre syndrome10.0CCR5
46glomerulonephritis10.0CCR5
47neuromyelitis optica10.0IFNB1
48silicosis10.0FASLG
49stomatitis10.0CSF2
50multiple myeloma10.0CXCL12

Graphical network of the top 20 diseases related to Cytomegalovirus Retinitis:



Diseases related to cytomegalovirus retinitis

Clinical Features for Cytomegalovirus Retinitis

Drugs & Therapeutics for Cytomegalovirus Retinitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Cytomegalovirus Retinitis

Drug clinical trials:

Search ClinicalTrials for Cytomegalovirus Retinitis

Search NIH Clinical Center for Cytomegalovirus Retinitis

Search CenterWatch for Cytomegalovirus Retinitis

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Cytomegalovirus Retinitis

Anatomical Context for Cytomegalovirus Retinitis

Sources:
33MalaCards
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MalaCards organs/tissues related to Cytomegalovirus Retinitis:

33
Bone marrow, Retina, Heart, Liver, Lung, Nk cells, T cells, B lymphoblasts, B cells, Endothelial

Animal Models for Cytomegalovirus Retinitis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

Publications for Cytomegalovirus Retinitis

Sources:
51PubMed
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Articles related to Cytomegalovirus Retinitis:

(show top 50)    (show all 518)
idTitleAuthorsYear
1
Cytomegalovirus Retinitis in an ALL child on exclusive chemotherapy treated successfully with intravitreal ganciclovir alone. (23042013)
2013
2
Sustained-release ganciclovir implant as prophylaxis for cytomegalovirus retinitis in a child undergoing bone marrow transplantation. (23619214)
2013
3
Multiple intravitreal injections of ganciclovir for cytomegalovirus retinitis after stem-cell transplantation. (23665863)
2013
4
The epidemiology and incidence of cytomegalovirus retinitis in the HIV population in Singapore over 6 years. (23074211)
2012
5
Association of host genetic risk factors with the course of cytomegalovirus retinitis in patients infected with human immunodeficiency virus. (21396623)
2011
6
Prevalence of cytomegalovirus retinitis in Tanzanians with low CD4 levels. (21106992)
2011
7
Fluocinolone acetonide implant (Retisert) for chronic cystoid macular edema in two patients with AIDS and a history of cytomegalovirus retinitis. (21595537)
2011
8
Cytomegalovirus retinitis associated with acquired immunodeficiency syndrome. (21542985)
2011
9
Valganciclovir in the treatment of cytomegalovirus retinitis in HIV-infected patients. (20234777)
2010
10
Fundus autofluorescence changes in cytomegalovirus retinitis. (19996825)
2010
11
Clinical features and outcomes of cytomegalovirus retinitis after transplantation. (17511815)
2008
12
Cytomegalovirus retinitis after hematopoietic stem cell transplantation with alemtuzumab. (18562004)
2008
13
Cytomegalovirus retinitis in chronic lymphocytic leukaemia. (16921344)
2007
14
The immediate early 2 protein of human cytomegalovirus (HCMV) mediates the apoptotic control in HCMV retinitis through up-regulation of the cellular FLICE-inhibitory protein expression. (17056549)
2006
15
Cytomegalovirus retinitis in a patient with non-Hodgkin's lymphoma: a diagnostic dilemma. (15751258)
2005
16
Cytomegalovirus retinitis after intravitreous triamcinolone in an immunocompetent patient. (16376669)
2005
17
Cytomegalovirus retinitis in an immunocompetent patient. (15824240)
2005
18
Valgancyclovir as maintenance therapy for cytomegalovirus retinitis in a lung transplant patient--a case report. (15621160)
2004
19
Human cytomegalovirus retinitis: pathogenicity, immune evasion and persistence. (12706995)
2003
20
Effect of anti-cytomegalovirus therapy on the incidence of immune recovery uveitis in AIDS patients with healed cytomegalovirus retinitis. (14516810)
2003
21
Endophthalmitis after ganciclovir implant in patients with AIDS and cytomegalovirus retinitis. (14516804)
2003
22
Long term visual outcome of patients with cytomegalovirus retinitis treated with highly active antiretroviral therapy. (12812884)
2003
23
Genotypic analysis of cytomegalovirus retinitis poorly responsive to intravenous ganciclovir but responsive to the ganciclovir implant. (12504692)
2003
24
Protease inhibitor therapy is associated with markedly prolonged time to relapse and improved survival in AIDS patients with cytomegalovirus retinitis. (11564333)
2001
25
Immune recovery uveitis in patients with AIDS and cytomegalovirus retinitis after highly active antiretroviral therapy. (10844056)
2000
26
Long-term sustained release of ganciclovir from biodegradable scleral implant for the treatment of cytomegalovirus retinitis. (10925134)
2000
27
Retinal pigment epithelial dysfunction in human immunodeficiency virus-infected patients with cytomegalovirus retinitis. (10201604)
1999
28
Cytomegalovirus retinitis in the era of highly active antiretroviral therapy (HAART). (10334120)
1999
29
Anterior uveitis associated with intravenous cidofovir use in patients with cytomegalovirus retinitis. (10502577)
1999
30
Ocular complications of intravenous cidofovir for cytomegalovirus retinitis in patients with AIDS. (10624432)
1999
31
Monitoring cytomegalovirus retinitis prevalence in an HIV-seropositive cohort: the assessment of improvements observed following the introduction of highly active antiretroviral triple therapy. (10582631)
1999
32
NK cell modulation of murine cytomegalovirus retinitis. (9637493)
1998
33
Cystoid macular edema associated with cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. (9512171)
1998
34
Survival of HIV-infected patients with cytomegalovirus retinitis under highly active antiretroviral therapy. Groupe d'EpidAcmiologie Clinique du SIDA en Aquitaine. (9875592)
1998
35
Increasing survival in AIDS patients with cytomegalovirus retinitis treated with combination antiretroviral therapy including HIV protease inhibitors. (9583601)
1998
36
High-dose (2000-microgram) intravitreous ganciclovir in the treatment of cytomegalovirus retinitis. (9709750)
1998
37
Lack of efficacy of cidofovir in treating AIDS-related cytomegalovirus retinitis after long-term treatment with ganciclovir. (9583613)
1998
38
Parenteral cidofovir for cytomegalovirus retinitis in patients with AIDS: the HPMPC peripheral cytomegalovirus retinitis trial. A randomized, controlled trial. Studies of Ocular complications of AIDS Research Group in Collaboration with the AIDS Clinical Trials Group. (9036798)
1997
39
Cytomegalovirus retinitis: decreased risk of bilaterality with increased use of systemic treatment. Swiss HIV Cohort Study Group. (9145735)
1997
40
Treatment of cytomegalovirus retinitis with the intraocular ganciclovir implant. (10168898)
1997
41
Treatment of cytomegalovirus retinitis: A growing number of options. (22514462)
1996
42
Treatment of cytomegalovirus retinitis in patients with AIDS. (8678370)
1996
43
Screening for cytomegalovirus retinitis in children. (8904861)
1996
44
An economic exploration of oral and intravenous ganciclovir in the induction and maintenance treatment of AIDS-related cytomegalovirus retinitis. (8940670)
1996
45
Oral ganciclovir for cytomegalovirus retinitis in patients with AIDS: results of two randomized studies. (9110065)
1996
46
Once-weekly intraocular injections of ganciclovir for maintenance therapy of cytomegalovirus retinitis: clinical and ocular outcome. (8699072)
1996
47
'Creeping' cytomegalovirus retinitis in AIDS. (8949729)
1996
48
Evidence of active cytomegalovirus infection in clinically stable HIV-infected individuals with CD4+ lymphocyte counts below 100/microliters of blood: features and relation to risk of subsequent CMV retinitis. (7552494)
1995
49
Combination of ganciclovir and granulocyte-macrophage colony-stimulating factor in the treatment of cytomegalovirus retinitis in AIDS patients. The ACTG 073 Team. (7875151)
1994
50
Nephrogenic diabetes insipidus associated with foscarnet treatment of cytomegalovirus retinitis. (2160217)
1990

Genetic Variations for Cytomegalovirus Retinitis

Expression for genes affiliated with Cytomegalovirus Retinitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cytomegalovirus Retinitis

Search GEO for disease gene expression data for Cytomegalovirus Retinitis.

Pathways for genes affiliated with Cytomegalovirus Retinitis

Sources:
30KEGG, 38NCBI BioSystems Database, 12EMD Millipore, 54Reactome, 52QIAGEN, 56SinoBiological, 53R&D Systems, 4Cell Signaling Technology
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Pathways related to Cytomegalovirus Retinitis according to GeneCards/GeneDecks:

(show top 50)    (show all 54)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2CSF2
210.1HLA-DRB1
3
Transcription Role of VDR in regulation of genes involved in osteoporosis
Hide members
9.9FASLG, IFNG
49.7CCR2, CCR5, CXCL12
59.5IL2, HLA-DRB1, HLA-DQB1
69.5TNF, IFNG, CCR2
7
Immune response Bacterial infections in normal airways
9.5IFNG, TNF, FASLG
89.5IL2, TNF, CCR2
99.4IFNG, HLA-DRB1, IL2
10
Hide members
9.4IL2, IL10RA, IFNB1
11
Hide members
9.4CCR5, HLA-DQB1, HLA-DRB1, IL10RA
129.4IFNG, TNF, IL2
139.3HLA-DQB1, HLA-DRB1, IL10
149.3IL10, IL10RA, TNF
159.3IL2, IL10, IFNG
16
Hide members
9.3IL10RA, CXCL12, CSF2, CCR5, CCR2
17
Hide members
9.3IL10RA, CXCL12, CSF2, CCR5, CCR2
18
Immune response IFN alpha/beta signaling pathway
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9.2HLA-A, HLA-B, IFNB1
19
Hide members
9.2HLA-A, HLA-DQB1, FASLG, TNF
209.2HLA-B, IFNB1, IFNG
219.2CSF2, HLA-DQB1, HLA-B, IL2
229.1HLA-DQB1, HLA-B, HLA-DRB1, HLA-A
239.1HLA-DQB1, HLA-B, HLA-DRB1, HLA-A
248.9IFNG, CSF2, TNF, IL10
258.9CCR5, HLA-B, HLA-A, HDAC9
26
Hide members
8.9IFNG, CSF2, TNF, FASLG, IL2
27
Hide members
8.8IFNG, TNF, IL10, IL2
288.8IFNG, TNF, FASLG, HLA-A, IL2
29
Hide members
8.8IFNG, TNF, FASLG, HLA-B, HLA-A
308.7IL10, FASLG, TNF, IFNG, IDO1
31
Hide members
8.7IFNG, TNF, HLA-DQB1, HLA-DRB1, IL2
328.7CCR2, IDO1, FASLG, CXCL12, IL10, IL2
33
Hide members
8.7CCR5, IFNG, FASLG, HLA-DRB1, HLA-A, IL2
34
Development PDGF signaling via STATs and NF-kB
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8.6IFNG, TNF, IL10RA, IL10, IL2
358.6CSF2, TNF, HLA-DRB1, CD9
36
Hide members
8.3IFNG, CSF2, TNF, FASLG, IL10, IL2
37
Hide members
8.3CCR5, IFNG, CSF2, TNF, IL10, IL2
388.3IL2, IL10, TNF, IFNB1, IFNG
398.3IFNG, IFNB1, CSF2, IL10RA, IL10, IL2
408.1IFNB1, TNF, HLA-DQB1, HLA-DRB1, IL10RA, IL10
418.1IFNG, HLA-DQB1, HLA-B, HLA-DRB1, HLA-A, IL10RA
42
Hide members
8.1IFNG, IFNB1, TNF, FASLG, IL10, IL2
43
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7.9CCR2, CCR5, CSF2, TNF, CXCL12, IL10RA
44
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7.9HDAC9, HLA-DRB1, HLA-DQB1, TNF, IFNG, IL10
45
Hide members
7.9CCR2, CCR5, IFNB1, CSF2, FASLG, HDAC9
46
Hide members
7.7IFNG, IFNB1, CSF2, HLA-DQB1, HLA-B, HLA-DRB1
47
Hide members
7.6IFNG, IFNB1, CSF2, TNF, FASLG, HLA-B
48
Hide members
7.5CCR2, IFNG, IFNB1, CSF2, HLA-DQB1, HLA-B
49
Hide members
7.3IFNG, IFNB1, TNF, FASLG, HLA-DQB1, HLA-B
50
Hide members
7.1IL10, IFNG, TNF, FASLG, HLA-DQB1, HLA-B

Compounds for genes affiliated with Cytomegalovirus Retinitis

Sources:
45Novoseek, 50PharmGKB, 11DrugBank, 29IUPHAR, 60Tocris Bioscience, 2BitterDB, 24HMDB
See all sources

Compounds related to Cytomegalovirus Retinitis according to GeneCards/GeneDecks:

(show top 50)    (show all 157)
idCompoundScoreTop Affiliating Genes
1endotoxin4510.6FASLG
2tacrolimus45 50 1111.9IFNG, FASLG, IL2
3cyclosporin a45 29 6011.8HLA-A, IFNG, HLA-B
4cycloheximide459.8IFNB1, FASLG, CXCL12
5pentoxifylline45 1110.8CSF2, CD9
6pge2459.7CSF2, HDAC9, IL2
7gm-csf45 2910.5IFNG, IL10, TNF
8mip 1alpha459.2CCR5, CSF2, TNF, IL10
9interferon gamma459.2IFNG, TNF, IL10, IL2
10quinine45 29 2 1112.1IL10, CXCL12, CSF2, IDO1, CCR5
11gold sodium thiomalate459.1IL2, HLA-DRB1, TNF, IFNG
12dexamethasone45 50 29 1112.0IDO1, IFNB1, CXCL12, HDAC9, FASLG
13groalpha459.0IL10, CSF2, TNF, CXCL12, CCR5
14cyclophosphamide45 50 1111.0CXCL12, CSF2, IL2, FASLG, IFNB1
15poly(i-c)459.0TNF, CSF2, IFNB1, IDO1, IFNG
162,5-oligoadenylate459.0IFNB1, TNF, HLA-B, IL2, IDO1
17il-12458.9CSF2, TNF, IFNG, IL2, IL10
18okt3458.9IL2, IFNG, CSF2, TNF, IL10
19glatiramer acetate45 119.8IL10, IL2, IFNG, IFNB1, HLA-DRB1
20rituximab45 50 1110.7IL2, CSF2, IL10, FASLG, TNF, CXCL12
21mdms458.7CCR5, CSF2, CD9, CXCL12, IL10
22natalizumab45 119.7IL10, TNF, IFNB1, IFNG
23ganciclovir45 119.6IFNB1, CD9, FASLG
24imiquimod45 29 60 1111.6IFNB1, IL10, TNF, FASLG, CSF2, IFNG
25ccl345 299.5IFNG, IL10, CXCL12, TNF, CCR5, IFNB1
26herbimycin a45 609.5CSF2, IFNB1, IFNG, TNF, CXCL12, IL2
27simvastatin45 50 60 29 11 2413.4IL10, FASLG, IFNB1, IFNG, CCR5, TNF
28ifn-alpha458.4CSF2, FASLG, IFNB1, IL2, IL10, CXCL12
29ionomycin458.4FASLG, IL10, CSF2, IFNG, IL2, TNF
30ivig458.3CCR5, IFNG, IFNB1, CSF2, TNF, FASLG
31polyinosinic-polycytidylic acid458.3IFNG, IL2, IL10, HLA-B, TNF, IFNB1
32tarc458.3CXCL12, CCR5, IFNG, IFNB1, CSF2, TNF
33ribavirin45 50 1110.3IL2, CCR5, IFNG, IL10, HLA-B, CSF2
34actinomycin d458.2IFNG, CCR5, FASLG, IFNB1, CSF2, TNF
355-aza-2deoxycytidine458.1CXCL12, HLA-B, FASLG, IFNB1, IFNG, HDAC9
36thalidomide45 50 60 1111.1IFNG, IL2, FASLG, HDAC9, IL10, TNF
37il 10458.0IL2, IL10, IL10RA, TNF, CSF2, CCR5
385fluorouracil458.0CSF2, FASLG, IFNG, IFNB1, HLA-A, CXCL12
39polysaccharide458.0HLA-B, CD9, FASLG, CSF2, IFNB1, CXCL12
40calcitriol45 60 11 2410.9IFNG, CSF2, HDAC9, TNF, IL2, IL10
41zidovudine45 118.9CCR5, IFNB1, CD9, IL10, CSF2, CXCL12
42sb 20358045 608.6IL10, TNF, FASLG, IFNG, HDAC9, CXCL12
43genistein45 29 60 2 11 2412.5CD9, IFNB1, CSF2, TNF, FASLG, CXCL12
44neopterin457.5IL10, CD9, TNF, CSF2, IDO1, IFNG
45vegf457.2TNF, CXCL12, IL2, IFNG, IFNB1, CSF2
46rantes457.1IDO1, IFNG, IFNB1, CSF2, TNF, FASLG
47oligonucleotide457.0CD9, FASLG, IDO1, HLA-DQB1, HLA-B, IFNB1
48ly294002456.9IFNB1, TNF, FASLG, HDAC9, CD9, CXCL12
49thymidine45 247.9IDO1, IFNG, IFNB1, CSF2, FASLG, CD9
50tyrosine455.8IDO1, CCR5, CXCL12, FASLG, HLA-DRB1, IFNB1

GO Terms for genes affiliated with Cytomegalovirus Retinitis

Sources:
16Gene Ontology
See all sources

Cellular components related to Cytomegalovirus Retinitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MHC class I protein complexGO:0426129.8HLA-A, HLA-B
2integral to lumenal side of endoplasmic reticulum membraneGO:0715569.3HLA-DQB1, HLA-B, HLA-DRB1, HLA-A
3ER to Golgi transport vesicle membraneGO:0125079.2HLA-DQB1, HLA-B, HLA-DRB1, HLA-A
4external side of plasma membraneGO:0098977.9CXCL12, CD9, HLA-DRB1, FASLG, TNF, IFNG
5extracellular regionGO:0055767.7IFNG, IFNB1, CSF2, TNF, FASLG, CXCL12
6extracellular spaceGO:0056157.5IFNG, IFNB1, CSF2, TNF, FASLG, CXCL12
7integral to plasma membraneGO:0058877.3CCR2, CCR5, TNF, FASLG, HLA-B, HLA-DRB1

Biological processes related to Cytomegalovirus Retinitis according to GeneCards/GeneDecks:

(show all 33)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of interleukin-23 productionGO:03274710.2IFNG, CSF2
2activation of necroptosis by extracellular signalsGO:06055510.1TNF, FASLG
3chemokine-mediated signaling pathwayGO:07009810.1CXCL12, CCR5, CCR2
4immunoglobulin production involved in immunoglobulin mediated immune responseGO:00238110.1HLA-DQB1, HLA-DRB1
5necrotic cell deathGO:07026510.1TNF, FASLG
6positive regulation of isotype switching to IgG isotypesGO:04830410.1IFNG, IL2
7positive regulation of vitamin D biosynthetic processGO:06055710.1TNF, IFNG
8humoral immune response mediated by circulating immunoglobulinGO:00245510.1HLA-DRB1, HLA-DQB1
9positive regulation of calcidiol 1-monooxygenase activityGO:06055910.0IFNG, TNF
10positive regulation of podosome assemblyGO:07180310.0CSF2, TNF
11positive regulation of monocyte chemotaxisGO:09002610.0CXCL12, CCR2
12positive regulation of peptidyl-serine phosphorylation of STAT proteinGO:03314110.0IFNG, IFNB1
13antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentGO:0024809.9HLA-A, HLA-B
14positive regulation of chemokine biosynthetic processGO:0450809.9TNF, IFNG
15positive regulation of MHC class II biosynthetic processGO:0453489.9IFNG, IL10
16receptor biosynthetic processGO:0328009.8TNF, IL10
17positive regulation of interferon-gamma productionGO:0327299.8CCR2, TNF, IL2
18negative regulation of cytokine secretion involved in immune responseGO:0027409.8TNF, IL10
19detection of bacteriumGO:0160459.8HLA-B, HLA-DRB1, HLA-A
20positive regulation of membrane protein ectodomain proteolysisGO:0510449.7TNF, IFNG
21negative regulation of growth of symbiont in hostGO:0441309.6IFNG, TNF, IL10
22cellular response to lipopolysaccharideGO:0712229.5IL10, CSF2, IFNG, CCR5
23humoral immune responseGO:0069599.5IFNG, IFNB1, TNF
24type I interferon-mediated signaling pathwayGO:0603379.5HLA-A, HLA-B, IFNB1
25elevation of cytosolic calcium ion concentrationGO:0072049.4CCR2, CCR5, IL2
26activation of cysteine-type endopeptidase activity involved in apoptotic processGO:0069199.3IFNB1, TNF, FASLG
27B cell proliferationGO:0421009.3IL10, IFNB1
28cell-cell signalingGO:0072679.3CCR5, FASLG, IL10, IL2
29response to virusGO:0096159.3IFNG, IFNB1, TNF, CXCL12
30interferon-gamma-mediated signaling pathwayGO:0603339.2IFNG, HLA-DQB1, HLA-B, HLA-DRB1, HLA-A
31inflammatory responseGO:0069548.8CCR2, CCR5, TNF, HDAC9, IL10
32cytokine-mediated signaling pathwayGO:0192218.5CCR2, IFNG, IFNB1, HLA-DQB1, HLA-B, HLA-DRB1
33immune responseGO:0069558.0IL2, CCR2, CCR5, CSF2, FASLG, HLA-DQB1

Molecular functions related to Cytomegalovirus Retinitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MHC class II receptor activityGO:0323959.8HLA-DRB1, HLA-DQB1
2C-C chemokine receptor activityGO:0164939.7CCR5, CCR2
3peptide antigen bindingGO:0426059.5HLA-A, HLA-DRB1, HLA-B
4receptor bindingGO:0051029.2FASLG, HLA-B, HLA-A, CXCL12
5growth factor activityGO:0080839.1CSF2, CXCL12, IL10, IL2
6cytokine activityGO:0051257.9IL2, IFNG, IFNB1, CSF2, TNF, FASLG

Products for genes affiliated with Cytomegalovirus Retinitis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cytomegalovirus Retinitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet