MCID: CYT005
MIFTS: 47

Cytomegalovirus Retinitis

Categories: Rare diseases, Eye diseases

Aliases & Classifications for Cytomegalovirus Retinitis

MalaCards integrated aliases for Cytomegalovirus Retinitis:

Name: Cytomegalovirus Retinitis 12 50 42 14 69
Cmv Retinitis 12 52

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology 12 DOID:0080160
MeSH 42 D017726

Summaries for Cytomegalovirus Retinitis

Disease Ontology : 12 A retinitis that has material basis in Cytomegalovirus.

MalaCards based summary : Cytomegalovirus Retinitis, also known as cmv retinitis, is related to cataract and autoimmune retinopathy. An important gene associated with Cytomegalovirus Retinitis is IL10RA (Interleukin 10 Receptor Subunit Alpha), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Cidofovir and Ganciclovir have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and t cells, and related phenotypes are cellular and hematopoietic system

Wikipedia : 72 Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that... more...

Related Diseases for Cytomegalovirus Retinitis

Diseases related to Cytomegalovirus Retinitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 164)
id Related Disease Score Top Affiliating Genes
1 cataract 30.2 CSF2 TNF
2 autoimmune retinopathy 29.9 HLA-DQB1 TNF
3 rheumatoid arthritis 26.8 CCR2 CSF2 HLA-B HLA-DQB1 IFNG TNF
4 retinitis 10.9
5 gigantism 10.6 HLA-B IL10RA
6 idiopathic subglottic tracheal stenosis 10.5 HLA-B HLA-DQB1
7 progressive myoclonus epilepsy 10.5 HLA-B HLA-DQB1
8 biemond syndrome 10.4 HLA-DQB1 TNF
9 primary biliary cirrhosis 10.4 IL10RA TNF
10 idiopathic dilatation of the pulmonary artery 10.4 HLA-DQB1 TNF
11 limb-body wall complex 10.4 HLA-DQB1 TNF
12 migraine with brainstem aura 10.4 HLA-B TNF
13 antigen-peptide-transporter 2 deficiency 10.4 HLA-B TNF
14 endocarditis 10.3 HLA-DQB1 TNF
15 not otherwise specified 3-mga-uria type 10.3 HLA-B TNF
16 aseptic meningitis 10.3 HLA-B TNF
17 gastroduodenal crohn's disease 10.3 CSF2 TNF
18 acquired immunodeficiency syndrome 10.3
19 ampulla of vater neoplasm 10.3 HLA-DQB1 TNF
20 liver leiomyoma 10.3 CCR5 TNF
21 human monocytic ehrlichiosis 10.2 HLA-DQB1 TNF
22 uveitis 10.2
23 noma 10.2 HLA-B TNF
24 moderately severe hemophilia b 10.2 HLA-DQB1 TNF
25 retinal detachment 10.2
26 high pressure neurological syndrome 10.2 HLA-B TNF
27 cantu sanchez-corona fragoso syndrome 10.1 CSF2 IFNG
28 optic nerve neoplasm 10.1 CSF2 IFNG
29 hunter macpherson syndrome 10.1 CSF2 IFNG
30 periodic paralysis with later-onset distal motor neuropathy 10.1 HLA-DQB1 IFNG
31 classic hairy cell leukemia 10.1 HLA-B HLA-DQB1
32 cutaneous candidiasis 10.1 CSF2 IFNG
33 papillary squamous carcinoma 10.1 HLA-DQB1 IFNG
34 sternal cleft 10.0 IFNG TNF
35 acanthoma 10.0 HLA-B IFNG
36 autoimmune polyglandular syndrome type 3 10.0 IFNG TNF
37 cryptococcosis 10.0 HLA-B HLA-DQB1 TNF
38 anaerobic meningitis 10.0 HLA-B HLA-DQB1 TNF
39 lymphoma 10.0
40 lung superior sulcus carcinoma 10.0 HLA-B HLA-DQB1 TNF
41 plantar wart 10.0 IFNG TNF
42 askin's tumor 10.0 IFNG IL10RA
43 amyotrophic lateral sclerosis type 10 10.0 IFNG TNF
44 leukemia 10.0
45 parametritis 10.0 IFNG TNF
46 polyarteritis nodosa 10.0 IFNG TNF
47 sparse hair ptosis mental retardation 10.0 IFNG TNF
48 spindle cell hemangioma 9.9 IFNG TNF
49 atrichia with papular lesions 9.9 IFNG TNF
50 hepatopulmonary syndrome 9.9 HLA-B HLA-DQB1 TNF

Graphical network of the top 20 diseases related to Cytomegalovirus Retinitis:



Diseases related to Cytomegalovirus Retinitis

Symptoms & Phenotypes for Cytomegalovirus Retinitis

MGI Mouse Phenotypes related to Cytomegalovirus Retinitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.98 CCR2 CCR5 CSF2 HLA-DQB1 IFNG IL10RA
2 hematopoietic system MP:0005397 9.97 CCR2 CCR5 CD9 CSF2 HLA-DQB1 IFNG
3 cardiovascular system MP:0005385 9.93 TNF CCR2 CCR5 CSF2 HLA-DQB1 IFNG
4 immune system MP:0005387 9.92 CCR2 CCR5 CD9 CSF2 HLA-DQB1 IFNG
5 digestive/alimentary MP:0005381 9.88 CCR2 CCR5 HLA-DQB1 IFNG IL10RA TNF
6 liver/biliary system MP:0005370 9.65 CCR2 CCR5 HLA-DQB1 IFNG TNF
7 neoplasm MP:0002006 9.55 CCR2 CCR5 CSF2 IFNG TNF
8 reproductive system MP:0005389 9.43 HLA-DQB1 IFNG TNF CCR5 CD9 CSF2
9 respiratory system MP:0005388 9.1 CCR2 CD9 CSF2 HLA-DQB1 IFNG TNF

Drugs & Therapeutics for Cytomegalovirus Retinitis

Drugs for Cytomegalovirus Retinitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 112)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cidofovir Approved Phase 4,Phase 3,Phase 2,Phase 1 113852-37-2 60613
2
Ganciclovir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 82410-32-0 3454
3
Foscarnet Approved Phase 4,Phase 3,Phase 2,Phase 1 63585-09-1, 4428-95-9 3415
4
Probenecid Approved Phase 4,Phase 2,Phase 1 57-66-9 4911
5
Phosphonoacetic Acid Experimental Phase 4,Phase 3,Phase 2,Phase 1 4408-78-0 546
6 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
7 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1
8 Ganciclovir triphosphate Phase 4,Phase 3,Phase 2,Phase 1
9 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
10 Anti-Retroviral Agents Phase 4,Phase 3,Phase 2,Phase 1
11 Reverse Transcriptase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
12 Antirheumatic Agents Phase 4,Phase 2,Phase 1
13 Renal Agents Phase 4,Phase 2,Phase 1
14
Valganciclovir Approved, Investigational Phase 3,Phase 2 175865-60-8 64147
15 Antibodies Phase 2, Phase 3,Phase 1
16 Antibodies, Monoclonal Phase 2, Phase 3,Phase 1
17 Immunoglobulins Phase 2, Phase 3,Phase 1
18 Acyclovir Phase 3
19
Nelfinavir Approved Phase 2 159989-64-7 64143
20 Fomivirsen Phase 2
21 Anti-HIV Agents Phase 2,Phase 1
22 HIV Protease Inhibitors Phase 2
23
protease inhibitors Phase 2
24 Pharmaceutical Solutions Phase 2
25
Aldesleukin Approved Phase 1 85898-30-2, 110942-02-4
26 Analgesics Phase 1
27 Analgesics, Non-Narcotic Phase 1
28 Interleukin-2 Phase 1
29 Peripheral Nervous System Agents Phase 1
30
Zidovudine Approved 30516-87-1 35370
31
Interferon beta-1b Approved 145155-23-3
32
Alfentanil Approved, Illicit 71195-58-9 51263
33
Aripiprazole Approved, Investigational 129722-12-9 60795
34
Ceftazidime Approved 78439-06-2, 72558-82-8 5481173
35
Ciprofloxacin Approved, Investigational 85721-33-1 2764
36
Clozapine Approved 5786-21-0 2818
37
Dexamethasone Approved, Investigational, Vet_approved 50-02-2 5743
38
Diazepam Approved, Illicit, Vet_approved 439-14-5 3016
39
Epinephrine Approved, Vet_approved 51-43-4 5816
40
Fosphenytoin Approved 93390-81-9 56339
41
Haloperidol Approved 52-86-8 3559
42
Heparin Approved, Investigational 9005-49-6 772 46507594
43
Hydromorphone Approved, Illicit 466-99-9 5284570
44
Meropenem Approved, Investigational 119478-56-7 64778 441130
45
Methylprednisolone Approved, Vet_approved 83-43-2 6741
46
Midazolam Approved, Illicit 59467-70-8 4192
47
Molindone Approved 7416-34-4 23897
48
Morphine Approved, Investigational 57-27-2 5288826
49
Nicardipine Approved 55985-32-5 4474
50
Olanzapine Approved, Investigational 132539-06-1 4585

Interventional clinical trials:

(show top 50) (show all 67)

id Name Status NCT ID Phase Drugs
1 Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis Completed NCT00000894 Phase 4 Cidofovir;Probenecid;Ganciclovir
2 A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium) Completed NCT00002125 Phase 4 Foscarnet sodium
3 Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration Completed NCT01866397 Phase 4
4 Use of Cidofovir for Recurrent Respiratory Papillomatosis Completed NCT00205374 Phase 4 Cidofovir;Placebo
5 Valganciclovir in Patients With CMV Retinitis and AIDS Who Cannot Take Drugs by Injection Unknown status NCT00017784 Phase 3 Valganciclovir
6 A Randomized, Controlled Study of Intravenous Ganciclovir Therapy for Peripheral Cytomegalovirus Retinitis in Patients With AIDS Completed NCT00000688 Phase 3 Ganciclovir
7 Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT) Completed NCT00000134 Phase 3 Ganciclovir;Foscarnet
8 Studies of the Ocular Complications of AIDS (SOCA)--Monoclonal Antibody CMV Retinitis Trial (MACRT) Completed NCT00000135 Phase 2, Phase 3 MSL-109
9 A Treatment Protocol for the Use of Intravenous Ganciclovir in AIDS Patients With Immediately Sight-Threatening CMV Retinitis Completed NCT00000698 Phase 3 Ganciclovir
10 Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT) Completed NCT00000143 Phase 3 Cidofovir intravenous
11 Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT) Completed NCT00000136 Phase 3 Foscarnet;Ganciclovir
12 Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis Completed NCT00002070 Phase 3 Sargramostim;Ganciclovir
13 Studies of the Ocular Complications of AIDS (SOCA)--HPMPC Peripheral CMV Retinitis Trial (HPCRT) Completed NCT00000142 Phase 2, Phase 3 Cidofovir
14 Ganciclovir Implant Study for Cytomegalovirus Retinitis Completed NCT00000118 Phase 3
15 A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes Completed NCT00002377 Phase 3 Valganciclovir;Ganciclovir
16 Valganciclovir in Prevention of Cytomegalovirus (CMV) Reactivation Following Allogeneic-Stem Cell Transplantation (SCT) Completed NCT00330018 Phase 3 Valganciclovir;Acyclovir
17 A Randomized Comparison of Intravitreal ISIS 2922 Plus Ganciclovir Versus Ganciclovir as Treatment for Patients With Cytomegalovirus Retinitis ( CMVR ) Completed NCT00002156 Phase 2 Fomivirsen sodium;Ganciclovir
18 Phase II Randomized Study of Cidofovir for Peripheral Cytomegalovirus Retinitis Completed NCT00004794 Phase 2 cidofovir
19 A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure Completed NCT00000691 Phase 2 Foscarnet sodium
20 CMV Retinitis Retreatment Trial Completed NCT00000766 Phase 2 Foscarnet sodium;Ganciclovir
21 The Safety and Effectiveness of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Completed NCT00002437 Phase 2 Cidofovir;Probenecid
22 The Safety and Effectiveness of ISIS 2922 in Patients With AIDS Who Have Cytomegalovirus (CMV) of the Eyes Completed NCT00002356 Phase 2 Fomivirsen sodium
23 A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis Completed NCT00002169 Phase 2 Nelfinavir mesylate
24 A Phase II/III Trial of Human Anti-CMV Monoclonal Antibody MSL 109 (MACRT) Completed NCT00000836 Phase 2 Sevirumab
25 Comparison of Two Methods in the Treatment of Cytomegalovirus of the Eyes in Patients With AIDS Completed NCT00001061 Phase 2 Sevirumab;Foscarnet sodium;Ganciclovir
26 The Safety and Effectiveness of Ganciclovir in the Prevention of Cytomegalovirus (CMV) of the Eyes and Disease of the Stomach and Intestines in Patients With HIV Completed NCT00001034 Phase 2 Ganciclovir
27 Congenital CMV and Hearing Loss in Children up to 4 Years of Age: Treating With Valganciclovir Therapy Recruiting NCT01649869 Phase 2 Valcyte (Valganciclovir hydrochloride) Powder for oral solution;Placebo
28 A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Cannot Use Ganciclovir Withdrawn NCT00000697 Phase 2 Foscarnet sodium
29 A Phase I/II Open-Labelled Trial of Intravitreal Ganciclovir Salvage Therapy for AIDS Patients With Active CMV Retinitis Who Are Intolerant of Systemic Therapy Completed NCT00000673 Phase 1 Ganciclovir
30 A Phase I/II Trial to Assess the Safety and Tolerance of Escalating Doses of a Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Retinitis Completed NCT00002016 Phase 1 Sevirumab
31 Foscarnet Treatment of Serious CMV Retinitis Infection in Patients With Acquired Immunodeficiency Syndrome Completed NCT00000726 Phase 1 Foscarnet sodium
32 A Study of Ganciclovir in the Treatment of Cytomegalovirus of the Eyes Completed NCT00001062 Phase 1 Ganciclovir
33 A Study of Foscarnet Plus Ganciclovir in the Treatment of Cytomegalovirus of the Eye in Patients With AIDS Who Have Already Been Treated With Ganciclovir Completed NCT00000970 Phase 1 Foscarnet sodium;Ganciclovir
34 A Phase I Study of the Safety of Proleukin (Aldesleukin) in Combination With Ganciclovir and Antiretroviral Therapy in HIV Seropositive Patients With Cytomegalovirus (CMV) Retinitis Completed NCT00002321 Phase 1 Aldesleukin
35 A Phase I Pharmacokinetic and Tolerance Study of 28-Day Regimens of Oral Ganciclovir Completed NCT00000668 Phase 1 Ganciclovir
36 A Pharmacokinetic and Tolerance Study of Oral Ganciclovir in HIV-Infected Children With Asymptomatic Cytomegalovirus Infection and Low CD4 Cell Counts or Quiescent Cytomegalovirus Disease Completed NCT00000805 Phase 1 Ganciclovir
37 A Study of Cidofovir in HIV-Infected Children With Cytomegalovirus (CMV) Disease Withdrawn NCT00000881 Phase 1 Cidofovir;Probenecid
38 A Study of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Unknown status NCT00002384 Cidofovir
39 A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir Unknown status NCT00002301 Foscarnet sodium
40 Suppression of Cytomegalovirus Retinitis Utilizing High Dose Intravenous Acyclovir and Oral Zidovudine in Patients With AIDS Completed NCT00000693 Zidovudine;Acyclovir
41 A Randomized Controlled Study of the Efficacy and Safety of Maintenance Treatment With Oral Ganciclovir for Newly Diagnosed Cytomegalovirus Retinitis in People With AIDS Completed NCT00002257 Ganciclovir
42 A Randomized, Controlled Study of the Safety and Preventive Efficacy of Oral Ganciclovir When Used in Conjunction With An Intravitreal Ganciclovir Implant in the Treatment of Cytomegalovirus Retinitis Completed NCT00002134 Ganciclovir
43 A Randomized Study Comparing the Safety and Efficacy of Two Regimens of Oral Ganciclovir to Intravenous Ganciclovir Maintenance Therapy for Cytomegalovirus Retinitis in People With AIDS Who Have Received Prior Ganciclovir Therapy Completed NCT00002247 Ganciclovir
44 A Study of the Safety and Tolerance of Long-Term Therapy With Intravenous Cytovene (Ganciclovir Sodium) for Cytomegalovirus Retinitis in Persons With AIDS Completed NCT00002034 Zidovudine;Ganciclovir
45 A Study of ISIS 2922 in the Treatment of Advanced Cytomegalovirus Retinitis Completed NCT00002187 Fomivirsen sodium
46 An Open-Label Study of the Safety and Efficacy of Cidofovir for the Treatment of Relapsing Cytomegalovirus Retinitis in Patients With AIDS Completed NCT00002142 Cidofovir;Probenecid
47 Efficacy of Elevated CD4 Counts on CMV Retinitis Completed NCT00091884
48 Studies of the Ocular Complications of AIDS (SOCA) CMV Retinitis Trial: Foscarnet-Ganciclovir Component Completed NCT00000665 Foscarnet sodium;Ganciclovir
49 A Study of Valganciclovir in the Treatment of Cytomegalovirus (CMV) Retinitis in Patients With AIDS Completed NCT00002222 Valganciclovir
50 HPMPC (Cidofovir) Peripheral CMV Retinitis Trial Protocol Completed NCT00000799 Cidofovir;Probenecid

Search NIH Clinical Center for Cytomegalovirus Retinitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: cytomegalovirus retinitis

Genetic Tests for Cytomegalovirus Retinitis

Anatomical Context for Cytomegalovirus Retinitis

MalaCards organs/tissues related to Cytomegalovirus Retinitis:

39
Eye, Retina, T Cells, Bone, Bone Marrow, Testes, Endothelial

Publications for Cytomegalovirus Retinitis

Articles related to Cytomegalovirus Retinitis:

(show top 50) (show all 578)
id Title Authors Year
1
Cytomegalovirus retinitis in Cape Town, South Africa: Clinical management and outcomes. ( 28604324 )
2017
2
OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN CYTOMEGALOVIRUS RETINITIS: A Longitudinal Study. ( 28145973 )
2017
3
Cytomegalovirus Retinitis: A Review. ( 28355091 )
2017
4
CYTOMEGALOVIRUS RETINITIS ASSOCIATED WITH OCCLUSIVE VASCULOPATHY IN AN ELDERLY, HUMAN IMMUNODEFICIENCY VIRUS-NEGATIVE MAN. ( 28937523 )
2017
5
Cytomegalovirus retinitis followed by immune recovery uveitis in an elderly patient with rheumatoid arthritis undergoing administration of methotrexate and tofacitinib combination therapy. ( 28389165 )
2017
6
Cytokine Profiles in Aqueous Humor and Plasma of HIV-infected Individuals with Ocular Syphilis or Cytomegalovirus Retinitis. ( 28081374 )
2017
7
Incidence Rates and Risk Factors for Vision Loss among AIDS-Related Cytomegalovirus Retinitis Patients in Southern Thailand. ( 28323489 )
2017
8
Cytomegalovirus Retinitis in Patients With Acquired Immunodeficiency Syndrome After Initiating Antiretroviral Therapy. ( 27984023 )
2017
9
COMPARISON OF VISUAL PROGNOSIS AND CLINICAL FEATURES OF CYTOMEGALOVIRUS RETINITIS IN HIV AND NON-HIV PATIENTS. ( 28118285 )
2017
10
Comparative analysis of cytomegalovirus retinitis and microvascular retinopathy in patients with acquired immunodeficiency syndrome. ( 28944199 )
2017
11
Cytomegalovirus retinitis in relapsed or refractory low-grade B cell lymphoma patients treated with bendamustine. ( 28447162 )
2017
12
Reduced frequency of murine cytomegalovirus retinitis in C57BL/6 mice correlates with low levels of suppressor of cytokine signaling (SOCS)1 and SOCS3 expression within the eye during corticosteroid-induced immunosuppression. ( 28558309 )
2017
13
Cytomegalovirus retinitis in a patient with secondary acute lymphosarcoma leukemia undergoing allogeneic hematopoietic stem-cell transplantation: A rare case report: a care-compliant article. ( 28489788 )
2017
14
Bilateral cytomegalovirus retinitis in a healthy infant. ( 28367531 )
2017
15
SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN MACULA-INVOLVING CYTOMEGALOVIRUS RETINITIS. ( 28376042 )
2017
16
Treatment outcomes of reduced-dose intravitreal ganciclovir for cytomegalovirus retinitis. ( 27090644 )
2016
17
Frosted branch angiitis in acquired immunodeficiency syndrome patients with cytomegalovirus retinitis. ( 27640360 )
2016
18
Management of Cytomegalovirus Retinitis in HIV and Non-HIV Patients. ( 26878441 )
2016
19
Cytomegalovirus retinitis in an immunocompetent patient: A case report. ( 27331155 )
2016
20
In Response to: Jeon and Lee's 'Cytomegalovirus Retinitis in a Human Immunodeficiency Virus-negative Cohort: Long-term Management and Complications'. ( 26943724 )
2016
21
Frosted Branch Angiitis Associated with Cytomegalovirus Retinitis. ( 26902566 )
2016
22
Immune recovery uveitis in HIV patients with cytomegalovirus retinitis in the era of HAART therapy-a 5-year study from Singapore. ( 27822743 )
2016
23
Good syndrome and other causes of cytomegalovirus retinitis in HIV-negative patients-case report and comprehensive review of the literature. ( 26809342 )
2016
24
Atypical Retinitis in the Setting of Prior Cytomegalovirus Retinitis. ( 27100908 )
2016
25
Long-term Follow-up of Cytomegalovirus Retinitis in Non-HIV Immunocompromised Patients: Clinical Features and Visual Prognosis. ( 27005706 )
2016
26
Dual Intravitreal Injections With Foscarnet and Ganciclovir for Ganciclovir-Resistant Recurrent Cytomegalovirus Retinitis in a Congenitally Infected Infant. ( 27783090 )
2016
27
Cytomegalovirus Retinitis as the First Manifestation of Good Syndrome. ( 27715373 )
2016
28
Leukaemic infiltration and cytomegalovirus retinitis in a patient with acute T-cell lymphoblastic leukaemia in complete remission. ( 27402450 )
2016
29
Diagnostic Utility of Ocular Symptoms and Vision for Cytomegalovirus Retinitis. ( 27788232 )
2016
30
Bilateral Cytomegalovirus Retinitis in a Patient with Systemic Lupus Erythematosus. ( 27462259 )
2016
31
Cytomegalovirus retinitis. ( 26684874 )
2016
32
Sensitivity of the Cytomegalovirus Antigenemia Assay to Diagnose Cytomegalovirus Retinitis. ( 27883376 )
2016
33
Cytomegalovirus Retinitis in a Patient Who Received Ruxolitinib. ( 26789901 )
2016
34
Cytomegalovirus retinitis in pediatric stem cell transplants: report of a recent cluster and the development of a screening protocol. ( 27746296 )
2016
35
Cytomegalovirus Retinitis and Uveitis. ( 26471353 )
2015
36
Effective treatment of cytomegalovirus retinitis and neuritis with retrobulbar ganciclovir after treosulfan-based autologous bone marrow transplant. ( 26638547 )
2015
37
Incidence Rate and Risk Factors for Contralateral Eye Involvement among Patients with AIDS and Cytomegalovirus Retinitis Treated with Local Therapy. ( 26327465 )
2015
38
Long-term Outcomes of Cytomegalovirus Retinitis in the Era of Modern Antiretroviral Therapy: Results from a United States Cohort. ( 25892019 )
2015
39
Retinal detachment associated with AIDS-related cytomegalovirus retinitis: risk factors in a resource-limited setting. ( 25448999 )
2015
40
Cytomegalovirus Retinitis in HIV-Negative Patients: A Practical Management Approach. ( 25556113 )
2015
41
Immune recovery uveitis in a patient with previously undiagnosed cytomegalovirus retinitis. ( 26531739 )
2015
42
Incidence Rate and Risk Factors for Contralateral Eye Involvement among Patients with AIDS and Cytomegalovirus Retinitis Treated with Local Therapy. ( 26258284 )
2015
43
Management of cytomegalovirus retinitis in HIV infection in the era of highly active antiretroviral therapy. ( 26232735 )
2015
44
Retrospective study of cytomegalovirus retinitis complicated with acquired immunodeficiency syndrome. ( 26309620 )
2015
45
Clinical Outcomes of Retinal Detachment Surgery following Cytomegalovirus Retinitis in Patients on Highly Active Anti-retroviral Therapy for Acquired Immune Deficiency Syndrome. ( 26221740 )
2015
46
Utility of Leflunomide in the Treatment of Drug Resistant Cytomegalovirus Retinitis. ( 26652481 )
2015
47
Cytomegalovirus Retinitis in a Human Immunodeficiency Virus-negative Cohort: Long-term Management and Complications. ( 25760914 )
2015
48
Retinal structural features of cytomegalovirus retinitis with acquired immunodeficiency syndrome: an adaptive optics imaging and optical coherence tomography study. ( 26148637 )
2015
49
Treatment of cytomegalovirus retinitis with cytomegalovirus-specific T-lymphocyte infusion. ( 25559515 )
2015
50
Cytomegalovirus Retinitis in Three Pediatric Cases with Acute Lymphoblastic Leukemia: Case Series and Review of the Literature. ( 26567834 )
2015

Variations for Cytomegalovirus Retinitis

Expression for Cytomegalovirus Retinitis

Search GEO for disease gene expression data for Cytomegalovirus Retinitis.

Pathways for Cytomegalovirus Retinitis

Pathways related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

(show all 35)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.78 CCR2 CCR5 CSF2 HLA-B HLA-DQB1 IFNG
2
Show member pathways
13.44 CCR2 CCR5 CSF2 IFNG IL10RA TNF
3
Show member pathways
13.2 CCR2 CCR5 CSF2 IL10RA TNF
4
Show member pathways
13.1 CCR2 CCR5 CSF2 IL10RA TNF
5
Show member pathways
12.67 HLA-B HLA-DQB1 IFNG TNF
6
Show member pathways
12.67 CCR2 CCR5 CSF2 HLA-B HLA-DQB1 IFNG
7
Show member pathways
12.62 HLA-B HLA-DQB1 IFNG TNF
8
Show member pathways
12.46 HLA-DQB1 IFNG IL10RA TNF
9
Show member pathways
12.36 CSF2 HLA-B IFNG TNF
10
Show member pathways
12.26 CCR5 CSF2 IFNG TNF
11 12.25 CSF2 HLA-B HLA-DQB1 TNF
12
Show member pathways
12.16 CSF2 IFNG TNF
13 12.09 HLA-B HLA-DQB1 IFNG IL10RA
14
Show member pathways
12.06 CSF2 IFNG IL10RA
15 12.01 HLA-DQB1 IFNG IL10RA TNF
16
Show member pathways
12 HLA-B IFNG TNF
17 11.87 CCR2 IFNG TNF
18 11.84 CSF2 IFNG TNF
19
Show member pathways
11.83 CCR5 HLA-DQB1 IFNG IL10RA TNF
20 11.75 CSF2 IFNG TNF
21
Show member pathways
11.62 CSF2 IFNG TNF
22 11.61 CSF2 IFNG TNF
23 11.61 CCR2 CCR5 IFNG IL10RA
24 11.61 CD9 CSF2 HLA-DQB1 TNF
25 11.51 CSF2 HLA-DQB1 IFNG TNF
26 11.5 CCR2 CSF2 TNF
27
Show member pathways
11.49 CSF2 IFNG TNF
28 11.35 CCR2 IFNG TNF
29 11.23 HLA-B IFNG
30 11.21 IFNG TNF
31
Show member pathways
11.21 CSF2 IFNG TNF
32 11.2 IL10RA TNF
33 11.16 IFNG TNF
34 11.06 CSF2 IFNG TNF
35 10.71 CCR2 CCR5 CSF2 IL10RA TNF

GO Terms for Cytomegalovirus Retinitis

Cellular components related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.65 CCR2 CCR5 CD9 HLA-B TNF
2 clathrin-coated endocytic vesicle membrane GO:0030669 9.32 CD9 HLA-DQB1
3 cell surface GO:0009986 9.26 CCR5 CD9 HLA-B TNF
4 integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 9.16 HLA-B HLA-DQB1
5 external side of plasma membrane GO:0009897 8.92 CCR5 CD9 IFNG TNF

Biological processes related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

(show all 21)
id Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.76 CCR5 CSF2 TNF
2 cell surface receptor signaling pathway GO:0007166 9.75 CCR5 CD9 IFNG
3 positive regulation of nitric oxide biosynthetic process GO:0045429 9.6 IFNG TNF
4 positive regulation of interferon-gamma production GO:0032729 9.59 CCR2 TNF
5 interferon-gamma-mediated signaling pathway GO:0060333 9.58 HLA-B HLA-DQB1 IFNG
6 extrinsic apoptotic signaling pathway GO:0097191 9.57 IFNG TNF
7 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.56 CSF2 TNF
8 protein import into nucleus, translocation GO:0000060 9.55 IFNG TNF
9 positive regulation of protein complex assembly GO:0031334 9.54 IFNG TNF
10 positive regulation of osteoclast differentiation GO:0045672 9.52 IFNG TNF
11 dendritic cell chemotaxis GO:0002407 9.51 CCR2 CCR5
12 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.49 IFNG TNF
13 negative regulation of growth of symbiont in host GO:0044130 9.48 IFNG TNF
14 positive regulation of podosome assembly GO:0071803 9.46 CSF2 TNF
15 positive regulation of chemokine biosynthetic process GO:0045080 9.43 IFNG TNF
16 antigen processing and presentation GO:0019882 9.43 HLA-B HLA-DQB1 IFNG
17 positive regulation of interleukin-23 production GO:0032747 9.37 CSF2 IFNG
18 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.32 IFNG TNF
19 cellular response to lipopolysaccharide GO:0071222 9.26 CCR5 CSF2 IFNG TNF
20 immune response GO:0006955 9.17 CCR2 CCR5 CSF2 HLA-B HLA-DQB1 IFNG
21 positive regulation of vitamin D biosynthetic process GO:0060557 9.16 IFNG TNF

Molecular functions related to Cytomegalovirus Retinitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.43 CSF2 IFNG TNF
2 peptide antigen binding GO:0042605 9.16 HLA-B HLA-DQB1
3 chemokine receptor activity GO:0004950 8.96 CCR2 CCR5
4 C-C chemokine receptor activity GO:0016493 8.62 CCR2 CCR5

Sources for Cytomegalovirus Retinitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
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36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
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52 Novoseek
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59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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