MCID: CYT006
MIFTS: 22

Cytoplasmic Body Myopathy malady

Summaries for Cytoplasmic Body Myopathy

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32MalaCards
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MalaCards: Cytoplasmic Body Myopathy is related to myopathy and myotonic dystrophy. An important gene associated with Cytoplasmic Body Myopathy is CHKB (choline kinase beta), and among its related pathways are Hypertrophic cardiomyopathy (HCM) and Striated Muscle Contraction. The compounds succinate and alpha-bungarotoxin have been mentioned in the context of this disorder. Related mouse phenotypes are limbs/digits/tail and muscle.

Aliases & Classifications for Cytoplasmic Body Myopathy

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42NIH Rare Diseases
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Aliases & Descriptions:

cytoplasmic body myopathy 42


Related Diseases for Cytoplasmic Body Myopathy

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Cytoplasmic Body Myopathy:



Diseases related to cytoplasmic body myopathy

Clinical Features for Cytoplasmic Body Myopathy

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Drugs & Therapeutics for Cytoplasmic Body Myopathy

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Cytoplasmic Body Myopathy

Search CenterWatch for Cytoplasmic Body Myopathy

Genetic Tests for Cytoplasmic Body Myopathy

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Anatomical Context for Cytoplasmic Body Myopathy

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Animal Models for Cytoplasmic Body Myopathy or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Cytoplasmic Body Myopathy:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.3DMD, SMN1, CHKB
2MP:00053698.0DMD, DES, CHKB, SMN1
3MP:00053768.0CHKB, SMN1, DES, DMD
4MP:00053867.9SMN1, CHKB, DES, DMD

Publications for Cytoplasmic Body Myopathy

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Genetic Variations for Cytoplasmic Body Myopathy

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Expression for genes affiliated with Cytoplasmic Body Myopathy

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Cytoplasmic Body Myopathy

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Pathways for genes affiliated with Cytoplasmic Body Myopathy

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Sources:
29KEGG, 37NCBI BioSystems Database, 53Reactome
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Pathways related to Cytoplasmic Body Myopathy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.3DES, DMD
2
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9.3DES, DMD

Compounds for genes affiliated with Cytoplasmic Body Myopathy

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Sources:
44Novoseek, 59Tocris Bioscience, 24HMDB, 28IUPHAR, 11DrugBank, 49PharmGKB, 2BitterDB
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Compounds related to Cytoplasmic Body Myopathy according to GeneCards/GeneDecks:

(show all 27)
idCompoundScoreTop Affiliating Genes
1succinate449.7CHKB, DMD
2alpha-bungarotoxin44 5910.7DES, DMD
3ornithine44 2410.7CHKB, DMD
4gemfibrozil44 28 1111.7CHKB, DES
5bezafibrate44 28 1111.7DES, CHKB
6prednisolone44 28 1111.7DMD, CHKB
7urea44 11 2411.7CHKB, DMD
8hematoxylin449.6DES, DMD
9azathioprine44 49 2 1112.6CHKB, DES
10biotin44 11 2411.6DES, DMD
11gold449.5DES, DMD
12bromodeoxyuridine449.5DES, DMD
13agarose449.5DMD, CHKB
14aminoglycosides449.5SMN1, DMD
15dihydrotestosterone44 28 11 2412.5DES, CHKB
16tacrolimus44 49 1111.3CHKB, DMD
17nacl449.3CHKB, DES
18polyacrylamide449.2DMD, DES, CHKB
19glycogen44 2410.2CHKB, DES, DMD
20creatinine449.1CHKB, DES, DMD
21heparin44 28 11 2412.1CHKB, DES, DMD
22glycerol44 11 2411.1CHKB, DMD
23adenylate449.1DMD, DES, CHKB
24nitric oxide44 11 2411.1DMD, DES, CHKB
25cysteine448.9CHKB, DES, DMD
26glucose448.8DMD, DES, CHKB
27arginine448.4SMN1, CHKB, DES, DMD

GO Terms for genes affiliated with Cytoplasmic Body Myopathy

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16Gene Ontology
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Cellular components related to Cytoplasmic Body Myopathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Z discGO:0300189.3DES, DMD
2sarcolemmaGO:0423839.0DES, DMD

Biological processes related to Cytoplasmic Body Myopathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:0300499.3DES, DMD

Molecular functions related to Cytoplasmic Body Myopathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:0052009.3DES, DMD

Products for genes affiliated with Cytoplasmic Body Myopathy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Cytoplasmic Body Myopathy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet