MCID: DCR003
MIFTS: 35

Dacryoadenitis malady

Categories: Eye diseases

Aliases & Classifications for Dacryoadenitis

Aliases & Descriptions for Dacryoadenitis:

Name: Dacryoadenitis 12 52 14 69
Dacryocystitis 42 69

Classifications:



External Ids:

Disease Ontology 12 DOID:950
ICD10 33 H04.0 H04.00
ICD9CM 35 375.0 375.00
MeSH 42 D003607
NCIt 47 C26971
UMLS 69 C0155223

Summaries for Dacryoadenitis

MalaCards based summary : Dacryoadenitis, also known as dacryocystitis, is related to acute dacryoadenitis and tuberculosis. An important gene associated with Dacryoadenitis is IL21 (Interleukin 21), and among its related pathways/superpathways are Innate Lymphoid Cell Differentiation Pathways and Dendritic Cells Developmental Lineage Pathway. The drugs Immunoglobulin G and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include eye, t cells and b cells, and related phenotype is normal.

Wikipedia : 71 Dacryoadenitis is inflammation of the lacrimal glands (the tear-producing... more...

Related Diseases for Dacryoadenitis

Diseases in the Dacryoadenitis family:

Chronic Dacryoadenitis Acute Dacryoadenitis

Diseases related to Dacryoadenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 114)
id Related Disease Score Top Affiliating Genes
1 acute dacryoadenitis 32.7 CD4 CD8A
2 tuberculosis 29.6 CD4 CD8A
3 allergic conjunctivitis 29.3 CD4 CD8A
4 dacryocystitis 12.3
5 acute dacryocystitis 12.0
6 chronic dacryocystitis 12.0
7 igg4-related dacryoadenitis and sialadenitis 11.9
8 chronic dacryoadenitis 11.9
9 phlegmonous dacryocystitis 11.9
10 osteopoikilosis and dacryocystitis 11.9
11 lacrimal duct defect 10.9
12 ophthalmia neonatorum 10.4
13 sialolithiasis 10.2 AQP5 IL21
14 growth hormone insensitivity, partial 10.2 AQP5 HSPG2
15 cellulitis 10.1
16 sialadenitis 10.1
17 hypoparathyroidism-retardation-dysmorphism syndrome 10.0 CD4 HSPG2
18 rheumatoid factor-negative juvenile idiopathic arthritis without anti-nuclear antibodies 10.0 CD4 HSPG2
19 alcoholic pancreatitis 10.0 CD4 CD8A
20 orbital disease 10.0 CD4 CD8A
21 colloid adenoma 10.0 CD4 CD8A
22 orbital cellulitis 10.0
23 retinal microaneurysm 10.0 CD4 CD8A
24 scrotum melanoma 10.0 CD4 CD8A
25 cervix melanoma 10.0 CD4 CD8A
26 coronin-1a deficiency 10.0 CD4 CD8A
27 scrotum squamous cell carcinoma 10.0 CD4 CD8A
28 eczema herpeticum 10.0 CD4 CD8A
29 infundibulocystic basal cell carcinoma 10.0 CD4 CD8A
30 mixed germ cell cancer 10.0 CD4 CD8A
31 vestibule of mouth cancer 10.0 CD4 CD8A
32 autoimmune polyendocrine syndrome type 1 10.0 CD4 CD8A
33 neuropathy, hereditary thermosensitive 10.0 CD4 CD8A
34 non-suppurative otitis media 10.0 CD4 CD8A
35 human immunodeficiency virus infectious disease 10.0 CD4 CD8A
36 lambda 5 deficiency 10.0 CD4 CD8A
37 cerebrum cancer 10.0 CD4 CD8A
38 herpetic whitlow 10.0 CD4 CD8A
39 dysentery 10.0 CD4 CD8A
40 dysplastic nevus syndrome 10.0 CD4 CD8A
41 extragonadal seminoma 10.0 CD4 CD8A
42 congenital hypothyroidism 10.0 CD4 CD8A
43 perinatal necrotizing enterocolitis 10.0 CD4 CD8A
44 sensory organ benign neoplasm 10.0 CD4 CD8A
45 bladder diverticulum 10.0 CD4 CD8A
46 phlyctenulosis 10.0 CD4 CD8A
47 rectum lymphoma 10.0 CD4 CD8A
48 tularemia 10.0 CD4 CD8A
49 rosacea conjunctivitis 10.0 CD4 CD8A
50 gluten allergy 10.0 CD4 CD8A

Graphical network of the top 20 diseases related to Dacryoadenitis:



Diseases related to Dacryoadenitis

Symptoms & Phenotypes for Dacryoadenitis

MGI Mouse Phenotypes related to Dacryoadenitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 normal MP:0002873 9.02 CD4 CD8A CTSZ IL21 VIL1

Drugs & Therapeutics for Dacryoadenitis

Drugs for Dacryoadenitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunoglobulin G
2 Immunoglobulins
3 Antibodies

Interventional clinical trials:


id Name Status NCT ID Phase
1 Evaluation and Treatment of Patients With Corneal and External Diseases Completed NCT00008541
2 A Prospective Cohort Study of IgG4RD in China Recruiting NCT01670695

Search NIH Clinical Center for Dacryoadenitis

Cochrane evidence based reviews: dacryocystitis

Genetic Tests for Dacryoadenitis

Anatomical Context for Dacryoadenitis

MalaCards organs/tissues related to Dacryoadenitis:

39
Eye, T Cells, B Cells, Skin, Myeloid, Salivary Gland, Tonsil

Publications for Dacryoadenitis

Articles related to Dacryoadenitis:

(show top 50) (show all 158)
id Title Authors Year
1
Bilateral Dacryoadenitis: Don't Forget Tuberculosis! ( 27956729 )
2017
2
Dacryoadenitis associated with IgG4-related disease in an Afro-Colombian adolescent. ( 27989497 )
2016
3
Idiopathic Dacryoadenitis: Clinical Features, Histopathology, and Treatment Outcomes. ( 26701269 )
2016
4
Lesional CD4+ IFN-I^+ cytotoxic T lymphocytes in IgG4-related dacryoadenitis and sialoadenitis. ( 27358392 )
2016
5
Adipose-Derived Mesenchymal Stem Cells Reduce Lymphocytic Infiltration in a Rabbit Model of Induced Autoimmune Dacryoadenitis. ( 27699412 )
2016
6
The pathological features of ectopic lymphoid neogenesis in idiopathic dacryoadenitis. ( 27230507 )
2016
7
Dacryoadenitis and extraocular muscle inflammation associated with contact lens-related Acanthamoeba keratitis: A case report and review of the literature. ( 27874294 )
2016
8
[Ophthalmoplegia without severe painful eyelid swelling in acute dacryoadenitis: a case report]. ( 26616487 )
2016
9
Relationship between dacryoadenitis subtype of idiopathic orbital inflammatory pseudotumor and paranasal sinusitis. ( 27158618 )
2016
10
Changes in Tear Film Characteristics in Patients with Idiopathic Dacryoadenitis. ( 26863039 )
2016
11
Acute Painful Ptosis Secondary to IgG4 Dacryoadenitis. ( 27293410 )
2016
12
First case report of isolated aspergillus dacryoadenitis. ( 27488157 )
2016
13
Bilateral dacryoadenitis as initial presentation of a locally aggressive and unresponsive limited form of orbital granulomatosis with polyangiitis. ( 27170605 )
2016
14
Preferential M2 macrophages contribute to fibrosis in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. ( 25450336 )
2015
15
Resolution of elevated circulating regulatory T cells by corticosteroids in patients with IgG4-related dacryoadenitis and sialoadenitis. ( 26385129 )
2015
16
The stiff elastographic change of submandibular glands rapidly improves after the introduction of glucocorticoid treatment in patients with IgG4-related dacryoadenitis and sialoadenitis. ( 26471698 )
2015
17
Immune complexome analysis of antigens in circulating immune complexes isolated from patients with IgG4-related dacryoadenitis and/or sialadenitis. ( 26166493 )
2015
18
Effectiveness of imaging modalities for screening IgG4-related dacryoadenitis and sialadenitis (Mikulicz's disease) and for differentiating it from SjAPgren's syndrome (SS), with an emphasis on sonography. ( 26298875 )
2015
19
Contact Lens-Related Acanthamoeba Keratitis and Accompanying Dacryoadenitis. ( 25603441 )
2015
20
Reversible lacrimal gland-protective regulatory T cell dysfunction underlies male-specific autoimmune dacryoadenitis in the nonobese diabetic mouse model of SjAPgren syndrome. ( 25581706 )
2015
21
Innate Immune Signaling Induces IL-7 Production, Early Inflammatory Responses, and SjAPgren's-Like Dacryoadenitis in C57BL/6 Mice. ( 26658504 )
2015
22
A case of marginal zone B cell lymphoma mimicking IgG4-related dacryoadenitis and sialoadenitis. ( 25889621 )
2015
23
Unique case of orbital myositis and dacryoadenitis preceding the vesicular rash of herpes zoster ophthalmicus. ( 26222135 )
2015
24
Dacryoadenitis associated with adenoviral keratoconjunctivitis. ( 26302257 )
2015
25
The many facets of dacryoadenitis. ( 26247137 )
2015
26
A case of mantle cell lymphoma presenting as IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. ( 26205396 )
2015
27
IgG4-Related Dacryoadenitis in a 13-Year-Old Girl. ( 24814270 )
2014
28
Granulomatous dacryoadenitis in regional enteritis (crohn disease). ( 25036879 )
2014
29
Methicillin-resistant Staphylococcus aureus dacryoadenitis. ( 24875129 )
2014
30
The role of cytotoxic T cells in IgG4-related dacryoadenitis and sialadenitis, the so-called Mikulicz's disease. ( 24593171 )
2014
31
Ocular Surface Disease and Dacryoadenitis in Aging C57BL/6 Mice. ( 24389165 )
2014
32
Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadenitis: Results from the SMART database. ( 25159154 )
2014
33
Surgical debulking for idiopathic dacryoadenitis: a diagnosis and a cure. ( 24572677 )
2014
34
Acute infantile dacryoadenitis. ( 24119874 )
2014
35
The diagnostic utility of biopsies from the submandibular and labial salivary glands in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. ( 25062551 )
2014
36
Bilateral dacryoadenitis as a presenting symptom of an extra-ocular disease. ( 24930462 )
2014
37
Idiopathic dacryoadenitis mimicking a primary intraocular tumour in a young girl. ( 24533840 )
2014
38
Bilateral self-inflicted infectious dacryoadenitis. ( 25208047 )
2014
39
Clinical relevance of KA1ttner tumour and IgG4-related dacryoadenitis and sialoadenitis. ( 24844187 )
2014
40
IgG4-related dacryoadenitis evolving into an extra-nodal, marginal zone B-cell lymphoma (EMZL): a tale of two lacrimal glands. ( 24977741 )
2014
41
Clinical Recognition and Management of an Atypical Dacryoadenitis. ( 25469005 )
2014
42
Acute suppurative bacterial dacryoadenitis: a rare case report. ( 24585426 )
2014
43
Tuberculous dacryoadenitis unveils HIV infection. ( 24093205 )
2013
44
A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of SjAPgren's syndrome. ( 23892265 )
2013
45
A case of IgG4-related dacryoadenitis that regressed without systemic steroid administration. ( 23801134 )
2013
46
Acute suppurative bacterial dacryoadenitis: a case series. ( 23603486 )
2013
47
T helper subsets in SjAPgren's syndrome and IgG4-related dacryoadenitis and sialoadenitis: A critical review. ( 23920005 )
2013
48
NK/T-cell lymphoma of the nasal cavity causing contralateral dacryoadenitis. ( 23663138 )
2013
49
Spontaneous regression of IgG4-related dacryoadenitis. ( 22886524 )
2013
50
Clinical features of IgG4-related dacryoadenitis. ( 24318531 )
2013

Variations for Dacryoadenitis

Expression for Dacryoadenitis

Search GEO for disease gene expression data for Dacryoadenitis.

Pathways for Dacryoadenitis

Pathways related to Dacryoadenitis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.22 CD4 CD8A
2 11.14 CD4 CD8A
3 11.01 CD4 CD8A
4 10.68 CD4 IL21
5 10.19 CD4 CD8A

GO Terms for Dacryoadenitis

Cellular components related to Dacryoadenitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 microvillus GO:0005902 8.96 AQP5 VIL1
2 T cell receptor complex GO:0042101 8.62 CD4 CD8A

Biological processes related to Dacryoadenitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of T cell proliferation GO:0042102 9.16 CD4 IL21
2 T cell activation GO:0042110 8.96 CD4 CD8A
3 positive regulation of calcium-mediated signaling GO:0050850 8.62 CD4 CD8A

Molecular functions related to Dacryoadenitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 coreceptor activity GO:0015026 8.62 CD4 CD8A

Sources for Dacryoadenitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....