Aliases & Classifications for Dacryoadenitis

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Aliases & Descriptions for Dacryoadenitis:

Name: Dacryoadenitis 11 49 13 67
 
Dacryocystitis 38 67

Classifications:



External Ids:

Disease Ontology11 DOID:950
ICD1029 H04.0, H04.00
ICD9CM31 375.0, 375.00
MeSH38 D003607
NCIt44 C26971

Summaries for Dacryoadenitis

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Wikipedia:70 Dacryoadenitis is inflammation of the lacrimal glands (the tear-producing glands). more...

MalaCards based summary: Dacryoadenitis, also known as dacryocystitis, is related to keratoconjunctivitis and dacryocystitis, and has symptoms including eyelid margin crusting, meibomian gland discharge and lid margin discharge. An important gene associated with Dacryoadenitis is IL21 (Interleukin 21), and among its related pathways are B Cell Development Pathways and CTLA4 Signaling. Affiliated tissues include eye, t cells and b cells, and related mouse phenotype normal.

Related Diseases for Dacryoadenitis

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Diseases in the Dacryoadenitis family:

Chronic Dacryoadenitis Acute Dacryoadenitis

Diseases related to Dacryoadenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 139)
idRelated DiseaseScoreTop Affiliating Genes
1keratoconjunctivitis30.3CD4, CD8A
2dacryocystitis12.3
3acute dacryocystitis12.0
4chronic dacryocystitis12.0
5acute dacryoadenitis12.0
6igg4-related dacryoadenitis and sialadenitis12.0
7chronic dacryoadenitis11.9
8phlegmonous dacryocystitis11.9
9osteopoikilosis and dacryocystitis11.9
10lacrimal duct defect10.9
11mucocele of salivary gland10.4AQP5, IL21
12endocarditis10.4CD4, HSPG2
13ophthalmia neonatorum10.4
14ocular hypertension10.3CD4, CD8A
15arteriovenous malformation10.3CD4, CD8A
16actinobacillosis10.3CD4, CD8A
17meckel's diverticulitis10.3CD4, CD8A
18scrotum squamous cell carcinoma10.3CD4, CD8A
19acute cystitis10.3CD4, CD8A
20folliculitis10.3CD4, CD8A
21cd3gamma deficiency10.3CD4, CD8A
22vaccinia10.3CD4, CD8A
23esophagus carcinoma in situ10.3CD4, CD8A
24intestinal disaccharidase deficiency10.3CD4, CD8A
25penis basal cell carcinoma10.3CD4, CD8A
26psoriasis10.3CD4, CD8A
27inhalation anthrax10.3CD4, CD8A
28neurotic excoriation10.3CD4, CD8A
29total internal ophthalmoplegia10.3CD4, CD8A
30soft palate cancer10.3CD4, CD8A
31agammaglobulinemia, microcephaly, and severe dermatitis10.3CD4, CD8A
32malignant eyelid melanoma10.3CD4, CD8A
33scleral disease10.3CD4, CD8A
34conventional leiomyosarcoma10.3CD4, CD8A
35complex partial epilepsy10.3CD4, CD8A
36kidney rhabdoid cancer10.3CD4, CD8A
37endometrioid ovary carcinoma10.3CD4, CD8A
38postcricoid region cancer10.3CD4, CD8A
39cauda equina syndrome10.3CD4, CD8A
40pneumonic tularemia10.3CD4, CD8A
41capgras syndrome10.3CD4, CD8A
42yellow fever10.3CD4, CD8A
43alkhurma hemorrhagic fever10.3CD4, CD8A
44autonomic peripheral neuropathy10.3CD4, CD8A
45vaginal squamous tumor10.3CD4, CD8A
46malignant histiocytosis10.3CD4, CD8A
47cd3delta deficiency10.3CD4, CD8A
48white piedra10.3CD4, CD8A
49neurilemmoma10.3CD4, CD8A
50mediastinum neurofibroma10.3CD4, CD8A

Graphical network of the top 20 diseases related to Dacryoadenitis:



Diseases related to dacryoadenitis

Symptoms for Dacryoadenitis

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UMLS symptoms related to Dacryoadenitis:


eyelid margin crusting, meibomian gland discharge, lid margin discharge, eyelid erythema

Drugs & Therapeutics for Dacryoadenitis

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Drugs for Dacryoadenitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1ImmunoglobulinsEarly Phase 16045
2Immunoglobulin GEarly Phase 1265
3AntibodiesEarly Phase 16045

Interventional clinical trials:

idNameStatusNCT IDPhase
1Cohort Study of IgG4RDUnknown statusNCT01670695Early Phase 1
2Evaluation and Treatment of Patients With Corneal and External DiseasesCompletedNCT00008541

Search NIH Clinical Center for Dacryoadenitis


Cochrane evidence based reviews: dacryocystitis

Genetic Tests for Dacryoadenitis

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Anatomical Context for Dacryoadenitis

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MalaCards organs/tissues related to Dacryoadenitis:

35
Eye, T cells, B cells, Tonsil, Myeloid, Skin, Salivary gland

Animal Models for Dacryoadenitis or affiliated genes

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MGI Mouse Phenotypes related to Dacryoadenitis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028737.9CD4, CD8A, CTSZ, IL21, VIL1

Publications for Dacryoadenitis

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Articles related to Dacryoadenitis:

(show top 50)    (show all 158)
idTitleAuthorsYear
1
Changes in Tear Film Characteristics in Patients with Idiopathic Dacryoadenitis. (26863039)
2016
2
Dacryoadenitis and extraocular muscle inflammation associated with contact lens-related Acanthamoeba keratitis: A case report and review of the literature. (27874294)
2016
3
The many facets of dacryoadenitis. (26247137)
2015
4
Resolution of elevated circulating regulatory T cells by corticosteroids in patients with IgG4-related dacryoadenitis and sialoadenitis. (26385129)
2015
5
A case of mantle cell lymphoma presenting as IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. (26205396)
2015
6
Innate Immune Signaling Induces IL-7 Production, Early Inflammatory Responses, and SjAPgren's-Like Dacryoadenitis in C57BL/6 Mice. (26658504)
2015
7
Bilateral dacryoadenitis as a presenting symptom of an extra-ocular disease. (24930462)
2014
8
The role of cytotoxic T cells in IgG4-related dacryoadenitis and sialadenitis, the so-called Mikulicz's disease. (24593171)
2014
9
Clinical Recognition and Management of an Atypical Dacryoadenitis. (25469005)
2014
10
Granulomatous dacryoadenitis in regional enteritis (crohn disease). (25036879)
2014
11
Ocular Surface Disease and Dacryoadenitis in Aging C57BL/6 Mice. (24389165)
2014
12
NK/T-cell lymphoma of the nasal cavity causing contralateral dacryoadenitis. (23663138)
2013
13
A case of IgG4-related dacryoadenitis that regressed without systemic steroid administration. (23801134)
2013
14
Dacryoadenitis as first presenting feature in systemic lupus erythematosus. (23884982)
2013
15
Acute suppurative bacterial dacryoadenitis: a case series. (23603486)
2013
16
Spontaneous regression of IgG4-related dacryoadenitis. (22886524)
2013
17
Deletion of interferon-I^ delays onset and severity of dacryoadenitis in CD25KO mice. (23116218)
2012
18
Simultaneous occurrence of IgG4-related chronic sclerosing dacryoadenitis and chronic sclerosing sialadenitis associated with lymph node involvement and Warthin's tumor. (19117975)
2011
19
Tuberculous dacryoadenitis in a child. (21876602)
2011
20
Na(+)/K(+)-ATPase in the lacrimal glands of rabbits and its changes during induced autoimmune dacryoadenitis. (21921989)
2011
21
Dacryoadenitis and diffuse orbital inflammation: unusual first presentations of Churg-Strauss syndrome. (21574807)
2011
22
Relationship between chronic sclerosing dacryoadenitis with high level of IgG4 and Castleman disease. (21311653)
2010
23
Expression of interleukin-17 in autoimmune dacryoadenitis in MRL/lpr mice. (20858106)
2010
24
Dacryoadenitis as a presenting feature of the Churg Strauss syndrome. (19444294)
2010
25
Bilateral dacryoadenitis: a new addition to the spectrum of reactive arthritis? (19300169)
2009
26
Autoimmune dacryoadenitis and keratoconjunctivitis induced in rabbits by subcutaneous injection of autologous lymphocytes activated ex vivo against lacrimal antigens. (18534818)
2008
27
Complication of IgG4-related chronic sclerosing dacryoadenitis by lymphoma. (18695125)
2008
28
Chronic sclerosing dacryoadenitis: part of the spectrum of IgG4-related Sclerosing disease? (17414116)
2007
29
Dacryoadenitis associated with Acanthamoeba keratitis. (16966617)
2006
30
Expression of TNF inhibitor gene in the lacrimal gland promotes recovery of tear production and tear stability and reduced immunopathology in rabbits with induced autoimmune dacryoadenitis. (15985164)
2005
31
Intralesional steroid injection for management of acute idiopathic dacryoadenitis: a preliminary result. (15778669)
2005
32
Tumor necrosis factor inhibitor gene expression suppresses lacrimal gland immunopathology in a rabbit model of autoimmune dacryoadenitis. (12792478)
2003
33
Lacrimal histopathology and ocular surface disease in a rabbit model of autoimmune dacryoadenitis. (12502944)
2003
34
Herpes simplex virus dacryoadenitis in an immunocompromised patient. (12796273)
2003
35
A case of acute dacryoadenitis associated with herpes zoster ophthalmicus. (12586188)
2003
36
Localized orbital inflammation: a case of dacryoadenitis. (10772228)
2000
37
Chronic dacryoadenitis misdiagnosed as eyelid edema and allergic conjunctivitis. (10340792)
1999
38
Pseudomonas dacryoadenitis secondary to a lacrimal gland ductule stone. (9185196)
1997
39
Adoptive transfer of experimental autoimmune dacryoadenitis in susceptible and resistant mice. (8370074)
1993
40
Wegener's granulomatosis presenting as dacryoadenitis. (1782785)
1991
41
Experimental autoimmune dacryoadenitis. I. Lacrimal gland disease in the rat. (8591907)
1987
42
Experimental autoimmune dacryoadenitis. II. Harderian gland disease in the rat. (8591908)
1987
43
Clinical and histocytopathological study of chronic dacryoadenitis. (6313486)
1983
44
Acute suppurative dacryoadenitis caused by a cysticercus cellulosa. (7097460)
1982
45
Harderian gland dacryoadenitis in rats resulting from orbital bleeding. (513634)
1979
46
Dacryoadenitis, conjunctivitis, and facial dermatitis of the mouse. (853714)
1977
47
Trachomatous acute palpebral dacryoadenitis. (6043485)
1967
48
A CASE OF ACUTE DACRYOADENITIS. (20321761)
1940
49
Acute Dacryoadenitis Caused by Focal Infection. (16692717)
1925
50
A Case of Acute Suppurative Dacryoadenitis. (16692254)
1912

Variations for Dacryoadenitis

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Expression for genes affiliated with Dacryoadenitis

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Search GEO for disease gene expression data for Dacryoadenitis.

Pathways for genes affiliated with Dacryoadenitis

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Pathways related to Dacryoadenitis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7CD4, IL21
29.5CD4, CD8A
39.5CD4, CD8A

GO Terms for genes affiliated with Dacryoadenitis

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Cellular components related to Dacryoadenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1T cell receptor complexGO:00421019.7CD4, CD8A
2microvillusGO:00059029.5AQP5, VIL1

Biological processes related to Dacryoadenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of calcium-mediated signalingGO:005085010.0CD4, CD8A
2positive regulation of T cell proliferationGO:00421029.7CD4, IL21
3T cell activationGO:00421109.5CD4, CD8A
4immune responseGO:00069558.9CD4, CD8A, IL21

Molecular functions related to Dacryoadenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1coreceptor activityGO:00150269.5CD4, CD8A

Sources for Dacryoadenitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet