MCID: DCR003
MIFTS: 35

Dacryoadenitis malady

Category: Eye diseases

Aliases & Classifications for Dacryoadenitis

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Aliases & Descriptions for Dacryoadenitis:

Name: Dacryoadenitis 11 50 13 68
 
Dacryocystitis 39 68

Classifications:



External Ids:

Disease Ontology11 DOID:950
ICD1030 H04.0, H04.00
ICD9CM32 375.0, 375.00
MeSH39 D003607
NCIt45 C26971

Summaries for Dacryoadenitis

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Wikipedia:71 Dacryoadenitis is inflammation of the lacrimal glands (the tear-producing glands). more...

MalaCards based summary: Dacryoadenitis, also known as dacryocystitis, is related to acute dacryoadenitis and tuberculosis. An important gene associated with Dacryoadenitis is IL21 (Interleukin 21), and among its related pathways are B Cell Development Pathways and Innate Lymphoid Cell Differentiation Pathways. Affiliated tissues include eye, t cells and b cells, and related mouse phenotype normal.

Related Diseases for Dacryoadenitis

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Diseases in the Dacryoadenitis family:

Chronic Dacryoadenitis Acute Dacryoadenitis

Diseases related to Dacryoadenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 114)
idRelated DiseaseScoreTop Affiliating Genes
1acute dacryoadenitis32.7CD4, CD8A
2tuberculosis29.6CD4, CD8A
3allergic conjunctivitis29.3CD4, CD8A
4dacryocystitis12.3
5acute dacryocystitis12.0
6chronic dacryocystitis12.0
7igg4-related dacryoadenitis and sialadenitis11.9
8chronic dacryoadenitis11.9
9phlegmonous dacryocystitis11.9
10osteopoikilosis and dacryocystitis11.9
11lacrimal duct defect10.9
12ophthalmia neonatorum10.4
13sialolithiasis10.2AQP5, IL21
14growth hormone insensitivity, partial10.2AQP5, HSPG2
15cellulitis10.1
16sialadenitis10.1
17hypoparathyroidism-retardation-dysmorphism syndrome10.0CD4, HSPG2
18rheumatoid factor-negative juvenile idiopathic arthritis without anti-nuclear antibodies10.0CD4, HSPG2
19alcoholic pancreatitis10.0CD4, CD8A
20orbital disease10.0CD4, CD8A
21colloid adenoma10.0CD4, CD8A
22orbital cellulitis10.0
23retinal microaneurysm10.0CD4, CD8A
24scrotum melanoma10.0CD4, CD8A
25cervix melanoma10.0CD4, CD8A
26coronin-1a deficiency10.0CD4, CD8A
27scrotum squamous cell carcinoma10.0CD4, CD8A
28eczema herpeticum10.0CD4, CD8A
29infundibulocystic basal cell carcinoma10.0CD4, CD8A
30mixed germ cell cancer10.0CD4, CD8A
31vestibule of mouth cancer10.0CD4, CD8A
32autoimmune polyendocrine syndrome type 110.0CD4, CD8A
33neuropathy, hereditary thermosensitive10.0CD4, CD8A
34non-suppurative otitis media10.0CD4, CD8A
35human immunodeficiency virus infectious disease10.0CD4, CD8A
36lambda 5 deficiency10.0CD4, CD8A
37cerebrum cancer10.0CD4, CD8A
38herpetic whitlow10.0CD4, CD8A
39dysentery10.0CD4, CD8A
40dysplastic nevus syndrome10.0CD4, CD8A
41extragonadal seminoma10.0CD4, CD8A
42congenital hypothyroidism10.0CD4, CD8A
43perinatal necrotizing enterocolitis10.0CD4, CD8A
44sensory organ benign neoplasm10.0CD4, CD8A
45bladder diverticulum10.0CD4, CD8A
46phlyctenulosis10.0CD4, CD8A
47rectum lymphoma10.0CD4, CD8A
48tularemia10.0CD4, CD8A
49rosacea conjunctivitis10.0CD4, CD8A
50gluten allergy10.0CD4, CD8A

Graphical network of the top 20 diseases related to Dacryoadenitis:



Diseases related to dacryoadenitis

Symptoms & Phenotypes for Dacryoadenitis

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MGI Mouse Phenotypes related to Dacryoadenitis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028737.7CD4, CD8A, CTSZ, IL21, VIL1

Drugs & Therapeutics for Dacryoadenitis

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Drugs for Dacryoadenitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Immunoglobulins6394
2Immunoglobulin G275
3Antibodies6394

Interventional clinical trials:

idNameStatusNCT IDPhase
1Evaluation and Treatment of Patients With Corneal and External DiseasesCompletedNCT00008541
2A Prospective Cohort Study of IgG4RD in ChinaRecruitingNCT01670695

Search NIH Clinical Center for Dacryoadenitis


Cochrane evidence based reviews: dacryocystitis

Genetic Tests for Dacryoadenitis

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Anatomical Context for Dacryoadenitis

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MalaCards organs/tissues related to Dacryoadenitis:

36
Eye, T cells, B cells, Tonsil, Myeloid, Skin, Salivary gland

Publications for Dacryoadenitis

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Articles related to Dacryoadenitis:

(show top 50)    (show all 158)
idTitleAuthorsYear
1
Bilateral Dacryoadenitis: Don't Forget Tuberculosis! (27956729)
2017
2
Dacryoadenitis associated with IgG4-related disease in an Afro-Colombian adolescent. (27989497)
2016
3
Idiopathic Dacryoadenitis: Clinical Features, Histopathology, and Treatment Outcomes. (26701269)
2016
4
Lesional CD4+ IFN-I^+ cytotoxic T lymphocytes in IgG4-related dacryoadenitis and sialoadenitis. (27358392)
2016
5
Adipose-Derived Mesenchymal Stem Cells Reduce Lymphocytic Infiltration in a Rabbit Model of Induced Autoimmune Dacryoadenitis. (27699412)
2016
6
The pathological features of ectopic lymphoid neogenesis in idiopathic dacryoadenitis. (27230507)
2016
7
Dacryoadenitis and extraocular muscle inflammation associated with contact lens-related Acanthamoeba keratitis: A case report and review of the literature. (27874294)
2016
8
Ophthalmoplegia without severe painful eyelid swelling in acute dacryoadenitis: a case report]. (26616487)
2016
9
Relationship between dacryoadenitis subtype of idiopathic orbital inflammatory pseudotumor and paranasal sinusitis. (27158618)
2016
10
Changes in Tear Film Characteristics in Patients with Idiopathic Dacryoadenitis. (26863039)
2016
11
Acute Painful Ptosis Secondary to IgG4 Dacryoadenitis. (27293410)
2016
12
First case report of isolated aspergillus dacryoadenitis. (27488157)
2016
13
Bilateral dacryoadenitis as initial presentation of a locally aggressive and unresponsive limited form of orbital granulomatosis with polyangiitis. (27170605)
2016
14
Preferential M2 macrophages contribute to fibrosis in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. (25450336)
2015
15
Resolution of elevated circulating regulatory T cells by corticosteroids in patients with IgG4-related dacryoadenitis and sialoadenitis. (26385129)
2015
16
The stiff elastographic change of submandibular glands rapidly improves after the introduction of glucocorticoid treatment in patients with IgG4-related dacryoadenitis and sialoadenitis. (26471698)
2015
17
Immune complexome analysis of antigens in circulating immune complexes isolated from patients with IgG4-related dacryoadenitis and/or sialadenitis. (26166493)
2015
18
Effectiveness of imaging modalities for screening IgG4-related dacryoadenitis and sialadenitis (Mikulicz's disease) and for differentiating it from SjAPgren's syndrome (SS), with an emphasis on sonography. (26298875)
2015
19
Contact Lens-Related Acanthamoeba Keratitis and Accompanying Dacryoadenitis. (25603441)
2015
20
Reversible lacrimal gland-protective regulatory T cell dysfunction underlies male-specific autoimmune dacryoadenitis in the nonobese diabetic mouse model of SjAPgren syndrome. (25581706)
2015
21
Innate Immune Signaling Induces IL-7 Production, Early Inflammatory Responses, and SjAPgren's-Like Dacryoadenitis in C57BL/6 Mice. (26658504)
2015
22
A case of marginal zone B cell lymphoma mimicking IgG4-related dacryoadenitis and sialoadenitis. (25889621)
2015
23
Unique case of orbital myositis and dacryoadenitis preceding the vesicular rash of herpes zoster ophthalmicus. (26222135)
2015
24
Dacryoadenitis associated with adenoviral keratoconjunctivitis. (26302257)
2015
25
The many facets of dacryoadenitis. (26247137)
2015
26
A case of mantle cell lymphoma presenting as IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. (26205396)
2015
27
IgG4-Related Dacryoadenitis in a 13-Year-Old Girl. (24814270)
2014
28
Granulomatous dacryoadenitis in regional enteritis (crohn disease). (25036879)
2014
29
Methicillin-resistant Staphylococcus aureus dacryoadenitis. (24875129)
2014
30
The role of cytotoxic T cells in IgG4-related dacryoadenitis and sialadenitis, the so-called Mikulicz's disease. (24593171)
2014
31
Ocular Surface Disease and Dacryoadenitis in Aging C57BL/6 Mice. (24389165)
2014
32
Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadenitis: Results from the SMART database. (25159154)
2014
33
Surgical debulking for idiopathic dacryoadenitis: a diagnosis and a cure. (24572677)
2014
34
Acute infantile dacryoadenitis. (24119874)
2014
35
The diagnostic utility of biopsies from the submandibular and labial salivary glands in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. (25062551)
2014
36
Bilateral dacryoadenitis as a presenting symptom of an extra-ocular disease. (24930462)
2014
37
Idiopathic dacryoadenitis mimicking a primary intraocular tumour in a young girl. (24533840)
2014
38
Bilateral self-inflicted infectious dacryoadenitis. (25208047)
2014
39
Clinical relevance of KA1ttner tumour and IgG4-related dacryoadenitis and sialoadenitis. (24844187)
2014
40
IgG4-related dacryoadenitis evolving into an extra-nodal, marginal zone B-cell lymphoma (EMZL): a tale of two lacrimal glands. (24977741)
2014
41
Clinical Recognition and Management of an Atypical Dacryoadenitis. (25469005)
2014
42
Acute suppurative bacterial dacryoadenitis: a rare case report. (24585426)
2014
43
Tuberculous dacryoadenitis unveils HIV infection. (24093205)
2013
44
A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of SjAPgren's syndrome. (23892265)
2013
45
A case of IgG4-related dacryoadenitis that regressed without systemic steroid administration. (23801134)
2013
46
Acute suppurative bacterial dacryoadenitis: a case series. (23603486)
2013
47
T helper subsets in SjAPgren's syndrome and IgG4-related dacryoadenitis and sialoadenitis: A critical review. (23920005)
2013
48
NK/T-cell lymphoma of the nasal cavity causing contralateral dacryoadenitis. (23663138)
2013
49
Spontaneous regression of IgG4-related dacryoadenitis. (22886524)
2013
50
Clinical features of IgG4-related dacryoadenitis. (24318531)
2013

Variations for Dacryoadenitis

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Expression for genes affiliated with Dacryoadenitis

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Search GEO for disease gene expression data for Dacryoadenitis.

Pathways for genes affiliated with Dacryoadenitis

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Pathways related to Dacryoadenitis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3CD4, IL21
29.1CD4, CD8A
39.1CD4, CD8A
49.1CD4, CD8A
59.1CD4, CD8A

GO Terms for genes affiliated with Dacryoadenitis

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Cellular components related to Dacryoadenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1microvillusGO:00059029.9AQP5, VIL1
2T cell receptor complexGO:00421019.1CD4, CD8A

Biological processes related to Dacryoadenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of T cell proliferationGO:00421029.8CD4, IL21
2positive regulation of calcium-mediated signalingGO:00508509.7CD4, CD8A
3T cell activationGO:00421109.1CD4, CD8A

Molecular functions related to Dacryoadenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1coreceptor activityGO:00150269.1CD4, CD8A

Sources for Dacryoadenitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet