Aliases & Classifications for Dacryoadenitis

MalaCards integrated aliases for Dacryoadenitis:

Name: Dacryoadenitis 12 51 14 69
Dacryocystitis 41 69

Classifications:



External Ids:

Disease Ontology 12 DOID:950
ICD10 32 H04.0 H04.00
ICD9CM 34 375.0 375.00
MeSH 41 D003607
NCIt 46 C26971
UMLS 69 C0155223

Summaries for Dacryoadenitis

MalaCards based summary : Dacryoadenitis, also known as dacryocystitis, is related to sialadenitis and igg4-related dacryoadenitis and sialadenitis. An important gene associated with Dacryoadenitis is IL21 (Interleukin 21), and among its related pathways/superpathways is G-protein signaling_Rap2B regulation pathway. The drugs Immunoglobulins and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include eye, t cells and thyroid, and related phenotype is digestive/alimentary.

Wikipedia : 72 Dacryoadenitis is inflammation of the lacrimal glands (the tear-producing... more...

Related Diseases for Dacryoadenitis

Diseases in the Dacryoadenitis family:

Acute Dacryoadenitis

Diseases related to Dacryoadenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)
# Related Disease Score Top Affiliating Genes
1 sialadenitis 30.1 AQP5 HSPG2
2 igg4-related dacryoadenitis and sialadenitis 12.4
3 osteopoikilosis and dacryocystitis 12.2
4 dacryocystitis 12.2
5 acute dacryocystitis 12.2
6 chronic dacryocystitis 12.1
7 acute dacryoadenitis 12.1
8 chronic dacryoadenitis 12.1
9 phlegmonous dacryocystitis 12.1
10 lacrimal duct defect 11.3
11 ophthalmia neonatorum 10.5
12 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.4
13 cellulitis 10.2
14 orbital cellulitis 10.1
15 mikulicz disease 10.1 AQP5 IL21
16 lymphoma 10.1
17 salivary gland disease 10.1 AQP5 HSPG2
18 aplasia of lacrimal and salivary glands 10.0 AQP5 HSPG2
19 keratoconjunctivitis 10.0
20 crohn's disease 9.9
21 keratitis, hereditary 9.9
22 mycobacterium tuberculosis 1 9.9
23 churg-strauss syndrome 9.9
24 conjunctivitis 9.9
25 acanthamoeba keratitis 9.9
26 lymphocytic hypophysitis 9.9
27 myositis 9.8
28 sjogren syndrome 9.8
29 meester-loeys syndrome 9.8
30 aging 9.8
31 wegener granulomatosis 9.8
32 episodic pain syndrome, familial, 1 9.8
33 b-cell lymphomas 9.8
34 marginal zone b-cell lymphoma 9.8
35 ptosis 9.8
36 keratoconjunctivitis sicca 9.8
37 thyroiditis 9.8
38 herpes zoster 9.8
39 herpes zoster ophthalmicus 9.8
40 lacrimal apparatus disease 9.8 AQP5 HSPG2
41 fibrosis of extraocular muscles, congenital, 1 9.6
42 systemic lupus erythematosus 9.6
43 body mass index quantitative trait locus 11 9.6
44 combined immunodeficiency, x-linked 9.6
45 leukemia, acute myeloid 9.6
46 body mass index quantitative trait locus 9 9.6
47 body mass index quantitative trait locus 8 9.6
48 body mass index quantitative trait locus 4 9.6
49 body mass index quantitative trait locus 10 9.6
50 body mass index quantitative trait locus 7 9.6

Graphical network of the top 20 diseases related to Dacryoadenitis:



Diseases related to Dacryoadenitis

Symptoms & Phenotypes for Dacryoadenitis

MGI Mouse Phenotypes related to Dacryoadenitis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 8.92 AQP5 CLCN2 HSPG2 IL13

Drugs & Therapeutics for Dacryoadenitis

Drugs for Dacryoadenitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunoglobulins
2 Antibodies

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation and Treatment of Patients With Corneal and External Diseases Completed NCT00008541
2 A Prospective Cohort Study of IgG4RD in China Recruiting NCT01670695

Search NIH Clinical Center for Dacryoadenitis

Cochrane evidence based reviews: dacryocystitis

Genetic Tests for Dacryoadenitis

Anatomical Context for Dacryoadenitis

MalaCards organs/tissues related to Dacryoadenitis:

38
Eye, T Cells, Thyroid, B Cells, Myeloid, Tonsil, Salivary Gland

Publications for Dacryoadenitis

Articles related to Dacryoadenitis:

(show top 50) (show all 168)
# Title Authors Year
1
Stage Classification of IgG4-related dacryoadenitis and sialadenitis by the Serum Cytokine Environment. ( 29385874 )
2018
2
Dacryoadenitis as the Initial Presentation of a Natural Killer T-Cell Lymphoma. ( 28328558 )
2017
3
Sarcoidosis presenting with acute dacryoadenitis. ( 29257721 )
2017
4
Bilateral Infiltrative Dacryoadenitis and Granulomatous Pneumonia in an 11-Year-Old Boy: A Case Report. ( 28444655 )
2017
5
Mesenchymal stem cells for treating autoimmune dacryoadenitis. ( 28583168 )
2017
6
A case of concurrent silent sinus syndrome, thyroid eye disease, idiopathic orbital inflammatory syndrome, and dacryoadenitis. ( 28812921 )
2017
7
Adipose-Derived Mesenchymal Stem Cells Reduce Lymphocytic Infiltration in a Rabbit Model of Induced Autoimmune Dacryoadenitis: Some Discussions. ( 28288268 )
2017
8
Interleukin-1 Inhibitors and Dacryoadenitis in Adult-Onset Still Disease. ( 29230477 )
2017
9
Bilateral subacute lacrimal gland enlargement mimicking dacryoadenitis in a 7-year-old boy: a rare adverse effect of valproic acid (sodium valproate). ( 28359767 )
2017
10
Bilateral Dacryoadenitis: Don't Forget Tuberculosis! ( 27956729 )
2017
11
Dacryoadenitis with Ptosis and Diplopia as the Initial Presentation of Granulomatosis with Polyangiitis. ( 28883246 )
2017
12
The pathological features of ectopic lymphoid neogenesis in idiopathic dacryoadenitis. ( 27230507 )
2016
13
Lesional CD4+ IFN-I^+ cytotoxic T lymphocytes in IgG4-related dacryoadenitis and sialoadenitis. ( 27358392 )
2016
14
Idiopathic Dacryoadenitis: Clinical Features, Histopathology, and Treatment Outcomes. ( 26701269 )
2016
15
Relationship between dacryoadenitis subtype of idiopathic orbital inflammatory pseudotumor and paranasal sinusitis. ( 27158618 )
2016
16
First case report of isolated aspergillus dacryoadenitis. ( 27488157 )
2016
17
Bilateral dacryoadenitis as initial presentation of a locally aggressive and unresponsive limited form of orbital granulomatosis with polyangiitis. ( 27170605 )
2016
18
Dacryoadenitis and extraocular muscle inflammation associated with contact lens-related Acanthamoeba keratitis: A case report and review of the literature. ( 27874294 )
2016
19
[Ophthalmoplegia without severe painful eyelid swelling in acute dacryoadenitis: a case report]. ( 26616487 )
2016
20
Adipose-Derived Mesenchymal Stem Cells Reduce Lymphocytic Infiltration in a Rabbit Model of Induced Autoimmune Dacryoadenitis. ( 27699412 )
2016
21
Dacryoadenitis associated with IgG4-related disease in an Afro-Colombian adolescent. ( 27989497 )
2016
22
Changes in Tear Film Characteristics in Patients with Idiopathic Dacryoadenitis. ( 26863039 )
2016
23
Acute Painful Ptosis Secondary to IgG4 Dacryoadenitis. ( 27293410 )
2016
24
A case of mantle cell lymphoma presenting as IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. ( 26205396 )
2015
25
Reversible lacrimal gland-protective regulatory T cell dysfunction underlies male-specific autoimmune dacryoadenitis in the nonobese diabetic mouse model of SjAPgren syndrome. ( 25581706 )
2015
26
Preferential M2 macrophages contribute to fibrosis in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. ( 25450336 )
2015
27
Contact Lens-Related Acanthamoeba Keratitis and Accompanying Dacryoadenitis. ( 25603441 )
2015
28
Unique case of orbital myositis and dacryoadenitis preceding the vesicular rash of herpes zoster ophthalmicus. ( 26222135 )
2015
29
Immune complexome analysis of antigens in circulating immune complexes isolated from patients with IgG4-related dacryoadenitis and/or sialadenitis. ( 26166493 )
2015
30
Resolution of elevated circulating regulatory T cells by corticosteroids in patients with IgG4-related dacryoadenitis and sialoadenitis. ( 26385129 )
2015
31
A case of marginal zone B cell lymphoma mimicking IgG4-related dacryoadenitis and sialoadenitis. ( 25889621 )
2015
32
Effectiveness of imaging modalities for screening IgG4-related dacryoadenitis and sialadenitis (Mikulicz's disease) and for differentiating it from SjAPgren's syndrome (SS), with an emphasis on sonography. ( 26298875 )
2015
33
Innate Immune Signaling Induces IL-7 Production, Early Inflammatory Responses, and SjAPgren's-Like Dacryoadenitis in C57BL/6 Mice. ( 26658504 )
2015
34
Dacryoadenitis associated with adenoviral keratoconjunctivitis. ( 26302257 )
2015
35
The stiff elastographic change of submandibular glands rapidly improves after the introduction of glucocorticoid treatment in patients with IgG4-related dacryoadenitis and sialoadenitis. ( 26471698 )
2015
36
The many facets of dacryoadenitis. ( 26247137 )
2015
37
Clinical relevance of KA1ttner tumour and IgG4-related dacryoadenitis and sialoadenitis. ( 24844187 )
2014
38
Methicillin-resistant Staphylococcus aureus dacryoadenitis. ( 24875129 )
2014
39
Bilateral self-inflicted infectious dacryoadenitis. ( 25208047 )
2014
40
Clinical Recognition and Management of an Atypical Dacryoadenitis. ( 25469005 )
2014
41
Bilateral dacryoadenitis as a presenting symptom of an extra-ocular disease. ( 24930462 )
2014
42
IgG4-related dacryoadenitis evolving into an extra-nodal, marginal zone B-cell lymphoma (EMZL): a tale of two lacrimal glands. ( 24977741 )
2014
43
The diagnostic utility of biopsies from the submandibular and labial salivary glands in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease. ( 25062551 )
2014
44
Granulomatous dacryoadenitis in regional enteritis (crohn disease). ( 25036879 )
2014
45
Ocular Surface Disease and Dacryoadenitis in Aging C57BL/6 Mice. ( 24389165 )
2014
46
Acute suppurative bacterial dacryoadenitis: a rare case report. ( 24585426 )
2014
47
Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadenitis: Results from the SMART database. ( 25159154 )
2014
48
Surgical debulking for idiopathic dacryoadenitis: a diagnosis and a cure. ( 24572677 )
2014
49
IgG4-Related Dacryoadenitis in a 13-Year-Old Girl. ( 24814270 )
2014
50
Acute infantile dacryoadenitis. ( 24119874 )
2014

Variations for Dacryoadenitis

Expression for Dacryoadenitis

Search GEO for disease gene expression data for Dacryoadenitis.

Pathways for Dacryoadenitis

Pathways related to Dacryoadenitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.7 HSPG2 IL13 IL21

GO Terms for Dacryoadenitis

Cellular components related to Dacryoadenitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 microvillus GO:0005902 8.62 AQP5 VIL1

Biological processes related to Dacryoadenitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 8.96 IL13 IL21
2 positive regulation of B cell proliferation GO:0030890 8.62 IL13 IL21

Molecular functions related to Dacryoadenitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine receptor binding GO:0005126 8.62 IL13 IL21

Sources for Dacryoadenitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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