MCID: DLY005
MIFTS: 36

Delayed Sleep Phase Syndrome malady

Genetic diseases (common) category

Aliases & Classifications for Delayed Sleep Phase Syndrome

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Aliases & Descriptions for Delayed Sleep Phase Syndrome:

Name: Delayed Sleep Phase Syndrome 49 47 65 67
Delayed Sleep Phase Syndrome, Susceptibility to 11
 
Dsps 67


Classifications:



External Ids:

OMIM49 614163
MeSH36 D020178

Summaries for Delayed Sleep Phase Syndrome

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OMIM:49 Delayed sleep phase syndrome is a circadian rhythm sleep disorder characterized by sleep-onset insomnia and difficulty... (614163) more...

MalaCards based summary: Delayed Sleep Phase Syndrome, also known as delayed sleep phase syndrome, susceptibility to, is related to arrhythmogenic right ventricular dysplasia 8 and woolly hair-palmoplantar keratoderma-dilated cardiomyopathy syndrome. An important gene associated with Delayed Sleep Phase Syndrome is AANAT (Aralkylamine N-Acetyltransferase), and among its related pathways are Circadian rhythm pathway and Metabolic States and Circadian Oscillators. Affiliated tissues include testes and brain, and related mouse phenotype nervous system.

UniProtKB/Swiss-Prot:67 Delayed sleep phase syndrome: A circadian rhythm sleep disorder characterized by sleep-onset insomnia and difficulty in awakening at the desired time. Patients with DSPS have chronic difficulty in adjusting their sleep-onset and wake-up times to occupational, school, and social activities.

Wikipedia:68 Delayed sleep-phase disorder (DSPD), also known as delayed sleep-phase syndrome (DSPS) or delayed... more...

Related Diseases for Delayed Sleep Phase Syndrome

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Diseases related to Delayed Sleep Phase Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 88)
idRelated DiseaseScoreTop Affiliating Genes
1arrhythmogenic right ventricular dysplasia 810.8
2woolly hair-palmoplantar keratoderma-dilated cardiomyopathy syndrome10.5
3skin fragility-woolly hair syndrome10.5
4skin fragility-woolly hair-palmoplantar keratoderma syndrome10.5
5cardiomyopathy, dilated, with woolly hair and keratoderma10.4
6epidermolysis bullosa, lethal acantholytic10.4
7chronobiology disease10.4
8sleep disorder10.4
9arrhythmogenic right ventricular cardiomyopathy10.4
10dilated cardiomyopathy with woolly hair, keratoderma, and tooth agenesis10.4
11dilated cardiomyopathy10.4
12long qt syndrome10.3
13dsp-related ectodermal dysplasia/skin fragility syndrome10.2
14adult syndrome10.1
15peeling skin syndrome 110.1
16obsessive-compulsive disorder10.1
17peeling skin syndrome 210.1
18exfoliation syndrome10.1
19peeling skin syndrome 310.1
20n syndrome10.1
21child syndrome10.1
22brain injury10.1
23traumatic brain injury10.1
24drug psychosis10.1
25spastic diplegia10.1
26chronic fatigue syndrome10.1
27peeling skin syndrome10.1
28eye accommodation disease10.1
29mood disorder10.1
30personality disorder10.1
31fountain syndrome10.1
32kid syndrome10.1
33young syndrome10.1
34headache10.1
35nevada syndrome10.1
36keratosis palmoplantaris striata ii10.1
37arrhythmogenic right ventricular dysplasia 110.1
38keratosis palmoplantaris striata i, ad10.1
39cardiac arrest10.1
40spinocerebellar ataxia10.1
41cardiomyopathy10.1
42neuroblastoma10.0
43lung cancer10.0
44prostate cancer10.0
45advanced sleep phase syndrome, familial, 110.0
46c syndrome10.0
47iga nephropathy 110.0
48advanced sleep-phase syndrome, familial, 210.0
49alopecia10.0
50cutaneous leishmaniasis10.0

Graphical network of the top 20 diseases related to Delayed Sleep Phase Syndrome:



Diseases related to delayed sleep phase syndrome

Symptoms for Delayed Sleep Phase Syndrome

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Clinical features from OMIM:

614163

Drugs & Therapeutics for Delayed Sleep Phase Syndrome

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Drugs for Delayed Sleep Phase Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Modafinilapproved, investigationalPhase 418968693-11-84236
Synonyms:
Dea No. 1680
Modafinil
Modafinil [USAN:INN]
Modafinil [Usan:Inn]
Modafinilo
Modafinilo [Spanish]
 
Modafinilum
Modafinilum [Latin]
Moderateafinil
Modiodal
Provigil
Sparlon
modafinil
2
Melatoninapproved, nutraceuticalPhase 4, Phase 121573-31-4896
Synonyms:
0E2B08C1-B325-45B1-8939-6F9081EFDFA4
4-ACETAMIDO-4'-ISOTHIO-CYANATOSTILBENE-2,2'-DISULFONIC ACID
5-22-12-00042 (Beilstein Handbook Reference)
5-Methoxy-N-acetyltryptamine
5-methoxy-N-acetyltryptamine
73-31-4
A4039/0172195
AB00053279
AC1L1A9Q
AC1Q4F1W
AC1Q4F1X
AKOS000276269
Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)- (9CI)
Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI)
Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI)
Acetamide, {N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-}
Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-}
BAS 01281092
BIDD:ER0618
BPBio1_000590
BRD-K97530723-001-07-6
BRN 0205542
BSPBio_000536
BSPBio_003006
Bio-0635
C01598
CAS-73-31-4
CCRIS 3472
CHEBI:16796
CHEMBL45
CID896
ChemDiv2_003916
Circadin
D008550
D08170
DB01065
DB08189
DivK1c_000353
EINECS 200-797-7
EU-0100787
HMS1380B22
HMS1569K18
HMS1921E04
HMS2089F09
HMS501B15
HSCI1_000400
HSDB 7509
I05-0076
I10-0345
IDI1_000353
IDI1_002631
IN1244
KBio1_000353
KBio2_000665
KBio2_003233
KBio2_005801
KBio3_002226
KBioGR_000591
KBioSS_000665
L001261
LS-1623
Lopac-M-5250
Lopac0_000787
M 5250
M-1200
M-1250
M1105
M5250_SIGMA
ML1
MLS000859594
MLS001055382
MLS001240204
MT6
Mela-T
Melapure
Melatol
Melatonex
Melatonex, Melatonin
Melatonin
Melatonin (synth.) standard-grade
 
Melatonin (synth.) ultra-pure
Melatonina
Melatonina (TN)
Melatonine
Melovine
MolPort-000-737-883
N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
N-(2-(5-Methoxyindol-3-yl)ethyl)-Acetamide
N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide
N-Acetyl-5-methoxy-tryptamine
N-Acetyl-5-methoxy-tryptamine Melatonine
N-Acetyl-5-methoxytryptamine
N-[2-(5-Methoxy-1H-indol-3-yl)-ethyl]-acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]-Acetamide
N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide
N-[2-(5-Methoxyindol-3-yl)ethyl]-Acetamide
N-[2-(5-Methoxyindol-3-yl)ethyl]acetamide
N-[2-(5-methoxyindol-3-yl)ethyl]acetamide
N-acetyl-5-methoxy-tryptamine
NCGC00015680-01
NCGC00015680-02
NCGC00015680-03
NCGC00015680-06
NCGC00015680-13
NCGC00090727-01
NCGC00090727-02
NCGC00090727-03
NCGC00090727-04
NCGC00090727-05
NCGC00090727-06
NCGC00090727-07
NCGC00090727-08
NCGC00090727-09
NCI60_004378
NINDS_000353
NMR/14327425
NSC 113928
NSC113928
NSC56423
Nature'S Harmony
Night Rest
Oprea1_104553
Oprea1_814234
PREVENTION 1 (MELATONIN) (PREVENTION 1)
PREVENTION 2 (MELATONIN)
PREVENTION 3 (MELATONIN)
PREVENTION 4 (MELATONIN)
PREVENTION 5 (MELATONIN)
Pineal Hormone
Posidorm
Prestwick0_000458
Prestwick1_000458
Prestwick2_000458
Prestwick3_000458
Prestwick_312
Regulin
Revital Melatonin
Rx Balance
S1204_Selleck
SDCCGMLS-0065812.P001
SDCCGMLS-0065812.P002
SMP2_000309
SMR000326666
SPBio_001527
SPBio_002475
SPECTRUM1500690
STK386880
Sleep Right
Spectrum2_001344
Spectrum3_001393
Spectrum4_000066
Spectrum5_001745
Spectrum_000185
TNP00300
UNII-JL5DK93RCL
Vivitas
WLN: T56 BMJ D2MV1 GO1
ZINC00057060
{N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-} Acetamide
{N-[2-(5-methoxyindol-3-yl)ethyl]-} Acetamide
3ArmodafinilPhase 4189
4
OxymetazolineapprovedPhase 23851491-59-44636
Synonyms:
1491-59-4
2-(4-Tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
2-(4-tert-Butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-6-tert-butyl-phenol
3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
3-[(4,5-dihydro-1H-Imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
6-Tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
6-t-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
6-tert-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
6-tert-Butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
AC-6370
AC1L1IM1
Afrin Cherry 12 Hour Nasal Spray
Afrin Extra Moisturizing 12 Hour Nasal Spray
Afrin Original 12 Hour Nasal Spray
Afrin Original 12 Hour Nose Drops
Afrin Original 12 Hour Pump Mist
Afrin Sinus 12 Hour Nasal Spray
BPBio1_000295
BPBio1_000419
BRD-K16195444-001-01-7
BRN 0886303
BSPBio_000267
BSPBio_002145
Biomol-NT_000161
C07363
CAS-151615
CHEBI:142520
CHEMBL762
CID4636
D010109
D08322
DB00935
DivK1c_000567
Dristan Long Lasting Mentholated Nasal Spray
Dristan Long Lasting Nasal Mist
Drixoral Nasal Solution
Duramist Plus Up To 12 Hour Nasal Decongestant Spray
EINECS 216-079-1
FT-0082560
Genasal Nasal Spray Up to 12 Hour Relief
H 990
HMS2089G03
HSDB 3143
Hazol
IDI1_000567
Iliadin
KBio1_000567
KBio2_001531
KBio2_004099
KBio2_006667
KBio3_001645
KBioGR_000908
KBioSS_001531
L000459
LS-104146
Lopac-O-2378
Lopac0_000903
 
MolPort-002-538-313
Mucinex Full Force
Mucinex Moisture Smart
NCGC00015766-01
NCGC00015766-02
NCGC00015766-03
NCGC00015766-10
NCGC00022345-02
NCGC00022345-04
NCGC00022345-05
NCGC00022345-06
NINDS_000567
Nafrine
Nasal Relief 12 Hour Nasal Spray
Navasin
Navisin
Neo-Synephrine 12 Hour Spray
Nezeril
Nostrilla 12 Hour Nasal Decongestant
Operil (TN)
Oximetazolina
Oximetazolina [INN-Spanish]
Oximetazolinum
Oxylazine
Oxymetazolina
Oxymetazoline (INN)
Oxymetazoline Hydrochloride
Oxymetazoline [INN:BAN]
Oxymetazoline hydrochloride
Oxymetazoline hydrochloride crystalline
Oxymetazolinum
Oxymetazolinum [INN-Latin]
Oxymethazoline
Oxymetozoline
Phenol, 3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl- (9CI)
Phenol, 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl- (7CI,8CI)
Prestwick0_000224
Prestwick1_000224
Prestwick2_000224
Prestwick3_000224
Rhinofrenol
Rhinolitan
SPBio_001095
SPBio_002188
Sinerol
Spectrum2_000998
Spectrum3_000533
Spectrum4_000464
Spectrum5_001114
Spectrum_001051
Tocris-1142
UNII-8VLN5B44ZY
Vicks Sinex 12 Hour Nasal Spray
Vicks Sinex 12 Hour Ultra Fine Mist for Sinus Relief
Visine L.R
Visine L.R.
nchembio705-11
oxymeta zoline
oxymetazoline
oxymetazoline hydrochloride crystalline
5
PhenylephrineapprovedPhase 238559-42-76041
Synonyms:
(-)-m-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol
(-)-m-Hydroxy-α-(methylaminomethyl)benzyl alcohol
(R)-2-Hydroxy-2-(3-hydroxyphenyl)-N-methylethylamine
(R)-3-Hydroxy-alpha-((methylamino)methyl)benzenemethanol
1416-03-1
3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol
59-42-7
61-76-7 (hydrochloride)
AC1L1LO9
AC1Q40UF
AI3-02402
AK-Dilate
AK-Nefrin
Adrianol
Ah-Chew
Ak-Dilate
Ak-Nefrin
Ak-dilate
Ak-nefrin
Alcon Efrin
Alcon efrin
Alconefrin Nasal Drops 12
Alconefrin Nasal Drops 25
Alconefrin Nasal Drops 50
Alconefrin Nasal Spray 25
BIDD:GT0157
BSPBio_002420
Benzenemethanol, 3-hydroxy-alpha-((methylamino)methyl)-, (R)- (9CI)
Biomydrin
C07441
CCRIS 8464
CHEBI:8093
CHEMBL1215
CID6041
Cyclomydril
D08365
DB00388
Dilatair
Dimetane
Dionephrine
DivK1c_000597
Doktors
Duration
EINECS 200-424-8
EINECS 215-810-1
Fenilefrina
Fenilefrina [INN-Spanish]
HSDB 3383
Help I Have A Stuffy Nose
I-Phrine
IDI1_000597
Isophrim
Isophrin
Isopto Frin
KBio1_000597
KBio2_001581
KBio2_004149
KBio2_006717
KBio3_001640
KBioGR_001313
KBioSS_001581
L-Phenylephedrine
L-Phenylephrine
LS-43027
Lopac-P-6126
Lopac0_000920
M-Methylaminoethanolphenol
M-Oxedrine
M-Sympathol
M-Sympatol
M-Synephrine
Mesaton
 
Mesatone
Mesatonum
Metaoxedrin
Metaoxedrine
Metaoxedrinum
Metasympatol
Metasynephrine
Metsatonum
Mezaton
Minims Phenylephrine
MolPort-001-792-191
Mydfrin
NCGC00015825-01
NCGC00015825-02
NCGC00024257-03
NCGC00024257-05
NCGC00024257-06
NINDS_000597
Neo-Synephrine
Neo-Synephrine Nasal Drops
Neo-Synephrine Nasal Jelly
Neo-Synephrine Nasal Spray
Neo-Synephrine Pediatric Nasal Drops
Neofrin
Neophryn
Neosynephrine
North Sinus Decongestant
Nostril
Nostril Spray Pump
Nostril Spray Pump Mild
Ocu-Phrin Sterile Eye Drops
Ocu-Phrin Sterile Ophthalmic Solution
Ocugestrin
P0395
PDSP1_001108
PDSP2_001092
Phenoptic
Phenylephrine
Phenylephrine (INN)
Phenylephrine Hydrochloride
Phenylephrine Minims
Phenylephrine Minims (TN)
Phenylephrine [INN:BAN]
Phenylephrine hydrochloride
Phenylephrinum
Phenylephrinum [INN-Latin]
Prefrin
Prefrin Liquifilm
Pyracort D
R(-)-Mezaton
R(-)-Phenylephrine
Relief Eye Drops for Red Eyes
Rhinall
SPBio_001280
Spectrum2_001280
Spectrum3_000770
Spectrum4_000967
Spectrum5_001411
Spectrum_001101
Spersaphrine
Tannins, compds. with (R)-3-hydroxy-alpha-((methylamino)methyl)benzenemethanol
UNII-1WS297W6MV
Vicks Sinex
Visadron
l-(3-Hydroxyphenyl)-N-methylethanolamine
l-1-(m-Hydroxyphenyl)-2-methylaminoethanol
l-alpha-Hydroxy-beta-methylamino-3-hydroxy-L-ethylbenzene
l-m-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol
m-Methylaminoethanolphenol
m-Oxedrine
m-Sympathol
m-Sympatol
m-Synephrine
phenylephrine
6
EpinephrineapprovedPhase 276851-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
Auvi-q
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
Epinephrine chloride
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr
Epipen Jr.
Epipen Jr. Auto-Injector
Epipen jr
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
 
Esphygmogenina
Exadrin
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
Primatene Mist Refill
Prime Asthma Relief
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
7
LidocaineapprovedPhase 2991137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Afterburn
Akten
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bikini Zone Medicated
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Bio-0767
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Bio1_000379
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Burn Relief Leader
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
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Cuivasil
Curacaine Transdermal Corporation
D00358
DB00281
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Diethylaminoaceto-2,6-xylidide
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DivK1c_000174
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EINECS 205-302-8
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FT-0082378
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HMS1791D21
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HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
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I01-2704
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IDI1_033829
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KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
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L0156
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LIDOPEN
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LS-805
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Lmx4
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Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Numb Master Topical Anesthetic
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Ocean Potion Instant Burn Relief Ice
Octocaine
Octocaine-100
Octocaine-50
Plum Smooth Plumb Numb Gelee
Premjact Male Desensitizer Pound International
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Recticare
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Simplicity Desensitizing
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Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Sole Serum
Spectrum2_001343
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Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Walgreens Aloe Vera Pain Relieving
Xilina
Xilocaina
Xilocaina [Italian]
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Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
8RacepinephrinePhase 2768
9Epinephryl boratePhase 2768
10
Cocaineapproved, illicit44150-36-25760, 446220
Synonyms:
(-)-Cocaine
(-)-Cocaine base
(1R,2R,3S,5S)-2-(methoxycarbonyl)tropan-3-yl benzoate
(1R,2R,3S,5S)-2-Methoxycarbonyltropan-3-yl benzoate
(R)-Cocaine
(−)-cocaine
1-Cocaine
1i7z
1q72
2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylate benzoate (ester)
2-beta-Carbomethoxy-3-beta-benzoxytropane
2-beta-Tropanecarboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate (ester)
2beta-Carbomethoxy-3beta-benzoxytropane
3-Tropanylbenzoate-2-carboxylic acid methyl ester
3beta-Hydroxy-2beta-tropanecarboxylic acid methyl ester benzoate (ester)
50-36-2
53-21-4 (hydrochloride)
610089_ALDRICH
610089_FLUKA
AC-16037
AC-20208
AC1L1EK2
AC1L1L2T
AC1L3U2D
AC1L9JBL
Allococaine
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Badrock
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Benzoylmethylecgonine
Bernice
Bernice [Street Name]
Bernies
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Blast
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C01416
C8912_SIGMA
CHEBI:27958
CID11779748
CID2826
CID446220
CID5760
COC
CPD-9776
Cabello
Candy
Carrie
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Charlie
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D00110
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DivK1c_000975
Dust
EINECS 200-032-7
Ecgonine methyl ester benzoate
Ecgonine methyl ester benzoate solution
Ecgonine, methyl ester, benzoate (ester)
 
Eritroxilina
Erytroxylin
Flake
Flake [Street Name]
Flex
Florida Snow
Foo Foo
Freeze
G-Rock
Girl
Girl [Street Name]
Gold Dust
Gold dust
Gold dust [Street Name]
Goofball
Green Gold
Green gold
HSDB 6469
Happy Dust
Happy Powder
Happy Trails
Happy dust
Happy dust [Street Name]
Happy powder
Happy trails
Heaven
Hell
IDI1_000975
Isocaine
Isococain
Isococaine
Jam
KBio1_000975
Kibbles N' Bits
Kibbles n' Bits
Kokain
Kokan
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L000836
LS-157759
Lady
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Leaf
MLS002320697
Methyl 3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
Methyl 3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester)
Methyl Benzoylecgonine
Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
Methyl benzoylecgonine
MolPort-002-535-520
MolPort-003-937-722
Moonrocks
NCGC00159467-02
NINDS_000975
Neurocaine
Nose candy
Pimp's Drug
Pimp's drug
Prime Time
Pseudoallococaine
Pseudococaine
Rock
Rock [Street Name]
SMR001338843
STOCK1N-68258
Sleighride
Snort
Snow
Snow (birds)
Star Dust
Star dust
Star-Spangled Powder
Star-spangled powder
Sugar
Sweet Stuff
Toke
Toot
Toot [Street Name]
Trails
UNII-I5Y540LHVR
White girl or lady
Yeyo
Zip
[1R-(Exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester
beta-Cocain
cocaine
cocainum
d-Pseudococaine
l-Cocain
methyl (1S,4R,5R)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
methyl (3S,4R)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
methyl 3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
nchembio.284-comp4

Interventional clinical trials:

(show all 20)
idNameStatusNCT IDPhase
1Randomized Controlled Trial on the Treatment Effects of Melatonin and Light Therapy on Delayed Sleep Phase SyndromeCompletedNCT00834886Phase 4
2Study to Evaluate Armodafinil Treatment in Improving Prefrontal Cortical Activation and Working Memory PerformanceCompletedNCT00711516Phase 4
3Evaluation of Modafinil vs Placebo for Treatment of Anesthesia Delayed Emergence in Obstructive Sleep ApneaRecruitingNCT02494102Phase 4
4Cognitive Behavioral Insomnia Therapy for Individuals With FibromyalgiaCompletedNCT00321451Phase 2, Phase 3
5Mild Cognitive Impairment and Obstructive Sleep ApneaCompletedNCT01482351Phase 3
6Intranasal Mometasone in Children With Obstructive Sleep Apnea Due to Adenotonsillar HypertrophyWithdrawnNCT01671852Phase 3
7Efficacy of Ramelteon on Speeding Up Sleep in Subjects With Delayed Sleep Phase SyndromeCompletedNCT00593736Phase 2
8Safety, Tolerability, Ascending Dose and Dose Frequency Study of rhHNS Via an IDDD in MPS IIIA PatientsCompletedNCT01155778Phase 1, Phase 2
9Randomized Clinical Trial of Nasal Turbinate Reduction to Improve Continuous Positive Airway Pressure (CPAP) Outcomes for Sleep ApneaCompletedNCT00503802Phase 2
10Extension of Study HGT-SAN-055 Evaluating Administration of rhHNS in Patients With Sanfilippo Syndrome Type A (MPS IIIA)Active, not recruitingNCT01299727Phase 1, Phase 2
11Synchronization and Desynchronization Between Circadian Rhythms in Patients With Delayed Sleep Phase Syndrome (DSPS)RecruitingNCT00282061Phase 1
12Treatment Strategies for Children With Smith-Magenis SyndromeRecruitingNCT00506259Phase 1
13Does Cognitive Behaviour Therapy (CBT) Improve the Effect of Light TherapyCompletedNCT01419938
14Effects of Light Treatment During Sleep on Young MenCompletedNCT00796939
15Sleep Length and Circadian Regulation in HumansCompletedNCT00843843
16Circadian Rhythms and Sleep in Familial DSPS and ASPSRecruitingNCT00246454
17Melatonin Treatment for Induced Transient InsomniaRecruitingNCT00950885
18Comparison of Dialysis Therapies on Cognitive FunctionRecruitingNCT00597103
19CPAP to Treat Cognitive Dysfunction in MSRecruitingNCT02544373
20Recognition and Early Intervention on Prodrome in Bipolar DisordersRecruitingNCT01863628

Search NIH Clinical Center for Delayed Sleep Phase Syndrome

Genetic Tests for Delayed Sleep Phase Syndrome

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Anatomical Context for Delayed Sleep Phase Syndrome

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MalaCards organs/tissues related to Delayed Sleep Phase Syndrome:

33
Testes, Brain

Animal Models for Delayed Sleep Phase Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Delayed Sleep Phase Syndrome:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.9AANAT, CLOCK, PER1, PER2, PER3

Publications for Delayed Sleep Phase Syndrome

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Articles related to Delayed Sleep Phase Syndrome:

(show top 50)    (show all 79)
idTitleAuthorsYear
1
Delayed sleep phase syndrome: a forerunner of psychiatric distress. (24304991)
2013
2
Relation between morningness-eveningness score and depressive symptoms among patients with delayed sleep phase syndrome. (21669551)
2011
3
Delayed sleep phase syndrome is related to seasonal affective disorder. (21601293)
2011
4
Antidepressant action of melatonin in the treatment of Delayed Sleep Phase Syndrome. (20044310)
2010
5
Clinical efficacy of dim light melatonin onset testing in diagnosing delayed sleep phase syndrome. (18725185)
2009
6
Sleep timing and circadian phase in delayed sleep phase syndrome. (19625733)
2009
7
A randomized, placebo-controlled trial of controlled release melatonin treatment of delayed sleep phase syndrome and impaired sleep maintenance in children with neurodevelopmental disabilities. (18078449)
2008
8
Delayed sleep phase syndrome, ADHD, and bright light therapy. (17335340)
2007
9
Constant light housing during nursing causes human DSPS (delayed sleep phase syndrome) behaviour in Clock-mutant mice. (17445238)
2007
10
Who is pre-occupied with sleep? A comparison of attention bias in people with psychophysiological insomnia, delayed sleep phase syndrome and good sleepers using the induced change blindness paradigm. (16704577)
2006
11
Attention bias for sleep-related stimuli in primary insomnia and delayed sleep phase syndrome using the dot-probe task. (17162988)
2006
12
Phase-dependent treatment of delayed sleep phase syndrome with melatonin. (16295212)
2005
13
Association of the length polymorphism in the human Per3 gene with the delayed sleep-phase syndrome: does latitude have an influence upon it? (15700718)
2005
14
Sleep and circadian rhythm disturbances in patients with delayed sleep phase syndrome. (14572116)
2003
15
Significant association of the arylalkylamine N-acetyltransferase (AA-NAT) gene with delayed sleep phase syndrome. (12736803)
2003
16
A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. (12841365)
2003
17
The psychological aspects of patients with delayed sleep phase syndrome (DSPS). (14592284)
2003
18
Hypersensitivity of melatonin suppression in response to light in patients with delayed sleep phase syndrome. (11379666)
2001
19
A pedigree of one family with delayed sleep phase syndrome. (11763990)
2001
20
Predisposing factors in delayed sleep phase syndrome. (11186112)
2000
21
Poor compensatory function for sleep loss as a pathogenic factor in patients with delayed sleep phase syndrome. (10875562)
2000
22
Posttraumatic delayed sleep phase syndrome. (10636163)
2000
23
Post-traumatic delayed sleep phase syndrome. (10994031)
2000
24
Is the delayed sleep phase syndrome a physical or psychological disease? A case report of disappearance following a change of latitude. (11043803)
2000
25
Effects of phototherapy on the phase relationship between sleep and body temperature rhythm in a delayed sleep phase syndrome case. (11186119)
2000
26
Possible association of human leucocyte antigen DR1 with delayed sleep phase syndrome. (10498237)
1999
27
Poor recovery sleep after sleep deprivation in delayed sleep phase syndrome. (10459687)
1999
28
Effects of phototherapy in patients with delayed sleep phase syndrome. (10459696)
1999
29
Light mask 500 lux treatment for delayed sleep phase syndrome. (10368853)
1999
30
Correlation between concentrations of melatonin in saliva and serum in patients with delayed sleep phase syndrome. (9558132)
1998
31
Melatonin-responsive headache in delayed sleep phase syndrome: preliminary observations. (9595871)
1998
32
Frequency of delayed sleep phase syndrome among hospitalized adolescent psychiatric patients. (9720851)
1998
33
Wrist activity rhythm and sleep diary of delayed sleep phase syndrome. (9628183)
1998
34
Vitamin B12 treatment for delayed sleep phase syndrome: a multi-center double-blind study. (9413873)
1997
35
Effects of light and chronotherapy on human circadian rhythms in delayed sleep phase syndrome: cytokines, cortisol, growth hormone, and the sleep-wake cycle. (8894073)
1996
36
Abnormal circadian rhythms of plasma melatonin and body temperature in the delayed sleep phase syndrome. (7897427)
1995
37
Delayed sleep phase syndrome: a review of its clinical aspects. (7694911)
1995
38
Melatonin and delayed sleep phase syndrome: ambulatory polygraphic evaluation. (7703401)
1994
39
Long-term course of adult patients with delayed sleep phase syndrome. (8301870)
1993
40
Successful combined treatment with vitamin B12 and bright artificial light of one case with delayed sleep phase syndrome. (8271628)
1993
41
Successful use of S20098 and melatonin in an animal model of delayed sleep-phase syndrome (DSPS). (8255922)
1993
42
A polysomnographic study on patients with delayed sleep phase syndrome (DSPS). (1635316)
1992
43
When the body clock goes wrong: delayed sleep phase syndrome. (1357304)
1992
44
A case with delayed sleep phase syndrome showing a significant seasonal variation in sleep-wake cycle. (1753481)
1991
45
Two cases of delayed sleep phase syndrome (DSPS). (1753473)
1991
46
Phase-shifting effects of bright morning light as treatment for delayed sleep phase syndrome. (2267478)
1990
47
A treatment trial of delayed sleep phase syndrome with triazolam. (2739169)
1989
48
Delayed sleep phase syndrome in adolescents. (3335467)
1988
49
Body temperature monitoring in subjects with delayed sleep phase syndrome. (3255890)
1988
50
Delayed sleep phase syndrome. A chronobiological disorder with sleep-onset insomnia. (7247637)
1981

Variations for Delayed Sleep Phase Syndrome

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UniProtKB/Swiss-Prot genetic disease variations for Delayed Sleep Phase Syndrome:

67
id Symbol AA change Variation ID SNP ID
1AANATp.Ala129ThrVAR_055086rs28936679

Clinvar genetic disease variations for Delayed Sleep Phase Syndrome:

5
id Gene Variation Type Significance SNP ID Assembly Location
1AANATNM_001166579.1(AANAT): c.520G> A (p.Ala174Thr)single nucleotide variantrisk factorrs28936679GRCh37Chr 17, 74465813: 74465813

Expression for genes affiliated with Delayed Sleep Phase Syndrome

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Search GEO for disease gene expression data for Delayed Sleep Phase Syndrome.

Pathways for genes affiliated with Delayed Sleep Phase Syndrome

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GO Terms for genes affiliated with Delayed Sleep Phase Syndrome

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Biological processes related to Delayed Sleep Phase Syndrome according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1response to light stimulusGO:000941610.1AANAT, PER1
2circadian regulation of translationGO:009716710.1PER1, PER2
3histone H3 deacetylationGO:007093210.0PER1, PER2
4entrainment of circadian clockGO:00096499.9CLOCK, PER1
5regulation of hair cycleGO:00426349.9CLOCK, PER1
6negative regulation of glucocorticoid receptor signaling pathwayGO:20003239.8CLOCK, PER1
7regulation of insulin secretionGO:00507969.8CLOCK, PER2
8regulation of circadian rhythmGO:00427529.8PER1, PER2
9response to cAMPGO:00515919.7AANAT, PER1
10negative regulation of transcription from RNA polymerase II promoterGO:00001228.9PER1, PER2, PER3
11negative regulation of transcription, DNA-templatedGO:00458928.7CLOCK, PER1, PER2
12circadian regulation of gene expressionGO:00329228.6CLOCK, PER1, PER2, PER3
13circadian rhythmGO:00076238.2AANAT, CLOCK, PER1, PER2, PER3
14transcription, DNA-templatedGO:00063518.1CLOCK, PER1, PER2, PER3

Molecular functions related to Delayed Sleep Phase Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcription regulatory region sequence-specific DNA bindingGO:00009769.6PER1, PER2
2chromatin DNA bindingGO:00314909.5CLOCK, PER1
3E-box bindingGO:00708889.5CLOCK, PER1
4kinase bindingGO:00199009.5PER1, PER3
5transcription factor activity, transcription factor bindingGO:00009899.3PER1, PER2

Sources for Delayed Sleep Phase Syndrome

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet