Dementia, Early-onset Progressive, Autosomal Recessive malady

MalaCards: Dementia, Early-onset Progressive, Autosomal Recessive, also known as dementia, is related to frontotemporal dementia and parkinson's disease. An important gene associated with Dementia, Early-onset Progressive, Autosomal Recessive is APP (amyloid beta (A4) precursor protein). The drugs citalopram hydrobromide and citalopram have been mentioned in the context of this disorder.

dementia, early-onset progressive, autosomal recessive 33 dementia 43

Diseases related to dementia, early-onset progressive, autosomal recessive by text searches and GeneDecks gene sharing:

(show top 50)    (show all 161)

id	Related Disease	Score	Top Affiliating Genes
1	frontotemporal dementia	11.7
2	parkinson's disease	10.4
3	lewy body dementia	9.3
4	amyotrophic lateral sclerosis	8.9
5	lateral sclerosis	8.8
6	aids dementia complex	8.8
7	down syndrome	8.8
8	cadasil	8.6
9	grn-related frontotemporal dementia	8.4
10	myopathy	8.2
11	tauopathy	8.0
12	immunodeficiency	7.9
13	inclusion body myopathy with early-onset paget disease and frontotemporal dementia	7.9
14	inclusion body myopathy	7.9
15	motor neuron disease	7.9
16	semantic dementia	7.9
17	frontotemporal dementia, chromosome 3-linked	7.8
18	frontotemporal dementia with parkinsonism-17	7.8
19	paget's disease of bone	7.8
20	pick's disease	7.5
21	binswanger's disease	7.5
22	inclusion body myopathy with paget disease of bone and/or frontotemporal dementia	7.4
23	schizophrenia	7.3
24	amyotrophic lateral sclerosis with frontotemporal dementia	7.1
25	nasu-hakola disease	7.1
26	supranuclear palsy	7.1
27	ataxia	7.0
28	cerebral atrophy	7.0
29	dementia, familial danish	7.0
30	multiple system atrophy	7.0
31	progressive supranuclear palsy	7.0
32	dementia - subcortical	6.7
33	frontotemporal dementia, ubiquitin-positive	6.7
34	gerstmann-straussler-scheinker disease	6.7
35	aphasia	6.5
36	dnmt1-related dementia, deafness, and sensory neuropathy	6.5
37	neuropathy	6.5
38	primary progressive aphasia	6.5
39	amyotrophic lateral sclerosis-parkinsonism/dementia complex 1	6.2
40	corticobasal degeneration	6.2
41	gliosis	6.2
42	jensen syndrome	6.2
43	normal pressure hydrocephalus	6.2
44	adult polyglucosan body disease	5.8
45	spasticity	5.8
46	tardbp-related frontotemporal dementia	5.8
47	chorea and dementia	5.8
48	creutzfeldt-jakob syndrome	5.8
49	dementia with epilepsy, mapt-related	5.8
50	ubqln2-related amyotrophic lateral sclerosis/frontotemporal dementia	5.8

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 citalopram, citalopram hydrobromide, prochlorperazine, prochlorperazine edisylate, prochlorperazine maleate, risperidone

Genes related to dementia, early-onset progressive, autosomal recessive according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	APP	amyloid beta (A4) precursor protein	11.1	Disorders